BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50046439 Cc1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H15F2NO2S/c1-12-2-4-13(5-3-12)16-10-18(20)19(21)11-17(16)14-6-8-15(9-7-14)25(22,23)24/h2-11H,1H3,(H2,22,23,24) IEPVUPAKSGZBAR-UHFFFAOYSA-N 50049645 4',5'-Difluoro-4-methyl-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::4',5'-Difluoro-4''-methyl-[1,1';2',1'']terphenyl-4-sulfonic acid amide::CHEMBL54370 Prostaglandin G/H synthase 1 Homo sapiens 17000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049645 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049645&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10666170 103979957 CHEMBL54370 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046441 COc1ccc(cc1F)-c1ccccc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H17FO3S/c1-24-20-12-9-15(13-19(20)21)18-6-4-3-5-17(18)14-7-10-16(11-8-14)25(2,22)23/h3-13H,1-2H3 ODBSRLCISKGYTE-UHFFFAOYSA-N 50049664 3-Fluoro-4''-methanesulfonyl-4-methoxy-[1,1';2',1'']terphenyl::CHEMBL54605 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049664 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049664&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10546170 103979976 CHEMBL54605 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046446 NS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc2OCOc2c1 InChI=1S/C19H13F2NO4S/c20-16-8-14(11-1-4-13(5-2-11)27(22,23)24)15(9-17(16)21)12-3-6-18-19(7-12)26-10-25-18/h1-9H,10H2,(H2,22,23,24) FJQRBWIOLPBVTA-UHFFFAOYSA-N 50049622 2'-Benzo[1,3]dioxol-5-yl-4',5'-difluoro-biphenyl-4-sulfonic acid amide::CHEMBL300600 Prostaglandin G/H synthase 1 Homo sapiens 1700 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049622 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049622&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10524370 103979934 CHEMBL300600 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046447 CN(C)c1ccc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H18ClF2NO2S/c1-25(2)21-9-6-14(10-18(21)22)17-12-20(24)19(23)11-16(17)13-4-7-15(8-5-13)28(3,26)27/h4-12H,1-3H3 QZSPOJXXPCQISC-UHFFFAOYSA-N 50049649 (3-Chloro-4',5'-difluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl-4-yl)-dimethyl-amine::CHEMBL299806 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049649 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049649&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10598294 103979961 CHEMBL299806 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046449 COc1ccc(cc1F)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H15F3O3S/c1-26-20-8-5-13(9-19(20)23)16-11-18(22)17(21)10-15(16)12-3-6-14(7-4-12)27(2,24)25/h3-11H,1-2H3 DYJXKHJKHDHNON-UHFFFAOYSA-N 50049634 3,4',5'-Trifluoro-4''-methanesulfonyl-4-methoxy-[1,1';2',1'']terphenyl::CHEMBL54649 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049634 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049634&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10548520 103979946 CHEMBL54649 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046450 CS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)cc1 InChI=1S/C19H15FO2S/c1-23(21,22)17-12-8-15(9-13-17)19-5-3-2-4-18(19)14-6-10-16(20)11-7-14/h2-13H,1H3 RFPZMXMBYMEQHZ-UHFFFAOYSA-N 50049631 4-Fluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::4''-Fluoro-4-methanesulfonyl-[1,1';2',1'']terphenyl::4''''-Fluoro-4-methanesulfonyl-[1,1'';2'',1'''']terphenyl::CHEMBL291912 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049631 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049631&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 9905412 103979943 CHEMBL291912 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046453 COc1c(Cl)cc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H14Cl2F2O3S/c1-27-20-16(21)7-12(8-17(20)22)15-10-19(24)18(23)9-14(15)11-3-5-13(6-4-11)28(2,25)26/h3-10H,1-2H3 ZWAVMLHHOIMTET-UHFFFAOYSA-N 50049648 3,5-Dichloro-4',5'-difluoro-4''-methanesulfonyl-4-methoxy-[1,1';2',1'']terphenyl::CHEMBL55224 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049648 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049648&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10789363 103979960 CHEMBL55224 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046455 Cc1ccc(cn1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C19H15F2NO2S/c1-12-3-4-14(11-22-12)17-10-19(21)18(20)9-16(17)13-5-7-15(8-6-13)25(2,23)24/h3-11H,1-2H3 MKFHCOCWLKUAMC-UHFFFAOYSA-N 50049628 5-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-2-methyl-pyridine::CHEMBL299251 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049628 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049628&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10570444 103979940 CHEMBL299251 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046457 CS(=O)(=O)c1ccc(cc1)-c1nccnc1-c1ccc(F)cc1 InChI=1S/C17H13FN2O2S/c1-23(21,22)15-8-4-13(5-9-15)17-16(19-10-11-20-17)12-2-6-14(18)7-3-12/h2-11H,1H3 KISKVCPIJSLUGE-UHFFFAOYSA-N 50049655 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazine::CHEMBL55189 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049655 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049655&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10735037 103979967 CHEMBL55189 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046459 COc1c(Cl)cc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H13Cl2F2NO3S/c1-27-19-15(20)6-11(7-16(19)21)14-9-18(23)17(22)8-13(14)10-2-4-12(5-3-10)28(24,25)26/h2-9H,1H3,(H2,24,25,26) FHVXNQKGIKQOCB-UHFFFAOYSA-N 50049621 3,5-Dichloro-4',5'-difluoro-4-methoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL300597 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049621 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049621&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 11797537 103979933 CHEMBL300597 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046461 CS(=O)(=O)c1ccc(cc1)-c1cc2OCOc2cc1-c1ccc(F)cc1 InChI=1S/C20H15FO4S/c1-26(22,23)16-8-4-14(5-9-16)18-11-20-19(24-12-25-20)10-17(18)13-2-6-15(21)7-3-13/h2-11H,12H2,1H3 SIGUPSKJHJMMAX-UHFFFAOYSA-N 50049650 5-(4-Fluoro-phenyl)-6-(4-methanesulfonyl-phenyl)-benzo[1,3]dioxole::CHEMBL298729 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049650 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049650&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10761664 103979962 CHEMBL298729 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046462 CS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc2OCCOc2c1 InChI=1S/C21H16F2O4S/c1-28(24,25)15-5-2-13(3-6-15)16-11-18(22)19(23)12-17(16)14-4-7-20-21(10-14)27-9-8-26-20/h2-7,10-12H,8-9H2,1H3 DLEXWYPUXDTMQV-UHFFFAOYSA-N 50049624 6-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-2,3-dihydro-benzo[1,4]dioxine::CHEMBL54746 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049624 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049624&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10597216 103979936 CHEMBL54746 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046463 NS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc2OCCOc2c1 InChI=1S/C20H15F2NO4S/c21-17-10-15(12-1-4-14(5-2-12)28(23,24)25)16(11-18(17)22)13-3-6-19-20(9-13)27-8-7-26-19/h1-6,9-11H,7-8H2,(H2,23,24,25) RKDRZOIGQPIOJE-UHFFFAOYSA-N 50049647 2'-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-4',5'-difluoro-biphenyl-4-sulfonic acid amide::CHEMBL55395 Prostaglandin G/H synthase 1 Homo sapiens 17900 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049647 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049647&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10787338 103979959 CHEMBL55395 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046466 NS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)c(Cl)c1 InChI=1S/C18H13ClFNO2S/c19-17-11-13(7-10-18(17)20)16-4-2-1-3-15(16)12-5-8-14(9-6-12)24(21,22)23/h1-11H,(H2,21,22,23) BRWDKJBTMKFKLU-UHFFFAOYSA-N 50049633 3-Chloro-4-fluoro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::3-Chloro-4-fluoro-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide::CHEMBL54412 Prostaglandin G/H synthase 1 Homo sapiens 9200 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049633 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049633&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10784838 103979945 CHEMBL54412 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046468 COc1ccc(cc1F)-c1ccccc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H16FNO3S/c1-24-19-11-8-14(12-18(19)20)17-5-3-2-4-16(17)13-6-9-15(10-7-13)25(21,22)23/h2-12H,1H3,(H2,21,22,23) VLZYADILQZRSFD-UHFFFAOYSA-N 50049661 3''''-Fluoro-4''''-methoxy-[1,1'';2'',1'''']terphenyl-4-sulfonic acid amide::3-Fluoro-4-methoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL442166 Prostaglandin G/H synthase 1 Homo sapiens 13200 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049661 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049661&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10808251 103979973 CHEMBL442166 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046470 Cc1cc(ccc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H14ClF2NO2S/c1-11-8-13(4-7-17(11)20)16-10-19(22)18(21)9-15(16)12-2-5-14(6-3-12)26(23,24)25/h2-10H,1H3,(H2,23,24,25) QRQGMZAVXNCVOI-UHFFFAOYSA-N 50049653 4-Chloro-4',5'-difluoro-3-methyl-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL55805 Prostaglandin G/H synthase 1 Homo sapiens 3900 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049653 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049653&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10810604 103979965 CHEMBL55805 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046473 COc1ccc(cc1Cl)-c1ccccc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H16ClNO3S/c1-24-19-11-8-14(12-18(19)20)17-5-3-2-4-16(17)13-6-9-15(10-7-13)25(21,22)23/h2-12H,1H3,(H2,21,22,23) YHPIWFZVGYDONZ-UHFFFAOYSA-N 50049618 3-Chloro-4-methoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::3-Chloro-4-methoxy-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide::CHEMBL54039 Prostaglandin G/H synthase 1 Homo sapiens 8200 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049618 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049618&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10523413 103979930 CHEMBL54039 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046475 COc1ccc(cc1Cl)-c1ccccc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H17ClO3S/c1-24-20-12-9-15(13-19(20)21)18-6-4-3-5-17(18)14-7-10-16(11-8-14)25(2,22)23/h3-13H,1-2H3 KZIVRPXSIUTGGU-UHFFFAOYSA-N 50049638 3-Chloro-4''-methanesulfonyl-4-methoxy-[1,1';2',1'']terphenyl::CHEMBL299567 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049638 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049638&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10667040 103979950 CHEMBL299567 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046476 Cc1ccc(nc1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C18H14F2N2O2S/c1-11-2-7-18(22-10-11)15-9-17(20)16(19)8-14(15)12-3-5-13(6-4-12)25(21,23)24/h2-10H,1H3,(H2,21,23,24) ABFBGNCEKVSSJD-UHFFFAOYSA-N 50049620 4',5'-Difluoro-2'-(5-methyl-pyridin-2-yl)-biphenyl-4-sulfonic acid amide::CHEMBL54619 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049620 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049620&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10784741 103979932 CHEMBL54619 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046478 Cc1ccc(nc1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C19H15F2NO2S/c1-12-3-8-19(22-11-12)16-10-18(21)17(20)9-15(16)13-4-6-14(7-5-13)25(2,23)24/h3-11H,1-2H3 YNOSXIZNGZQQRP-UHFFFAOYSA-N 50049626 2-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-5-methyl-pyridine::CHEMBL292607 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049626 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049626&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10522463 103979938 CHEMBL292607 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046479 Cc1ccc(cc1C)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H18F2O2S/c1-13-4-5-16(10-14(13)2)19-12-21(23)20(22)11-18(19)15-6-8-17(9-7-15)26(3,24)25/h4-12H,1-3H3 XUKVJQAMNLZRMM-UHFFFAOYSA-N 50049640 4',5'-Difluoro-4''-methanesulfonyl-3,4-dimethyl-[1,1';2',1'']terphenyl::CHEMBL300601 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049640 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049640&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10595453 103979952 CHEMBL300601 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046481 COc1ccc(cc1C)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H18F2O3S/c1-13-10-15(6-9-21(13)26-2)18-12-20(23)19(22)11-17(18)14-4-7-16(8-5-14)27(3,24)25/h4-12H,1-3H3 WYZSVZCOXZSTPN-UHFFFAOYSA-N 50049636 4',5'-Difluoro-4''-methanesulfonyl-4-methoxy-3-methyl-[1,1';2',1'']terphenyl::CHEMBL418448 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049636 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049636&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10739009 103979948 CHEMBL418448 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046484 Cc1cc(ccc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H15ClF2O2S/c1-12-9-14(5-8-18(12)21)17-11-20(23)19(22)10-16(17)13-3-6-15(7-4-13)26(2,24)25/h3-11H,1-2H3 SXRSLXYKFPVRRL-UHFFFAOYSA-N 50049617 4-Chloro-4',5'-difluoro-4''-methanesulfonyl-3-methyl-[1,1';2',1'']terphenyl::CHEMBL57837 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049617 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049617&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10572620 103979929 CHEMBL57837 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046486 COc1ccc(cc1OC)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C20H17F2NO4S/c1-26-19-8-5-13(9-20(19)27-2)16-11-18(22)17(21)10-15(16)12-3-6-14(7-4-12)28(23,24)25/h3-11H,1-2H3,(H2,23,24,25) DYBYPXGXLZNZQU-UHFFFAOYSA-N 50049616 4',5'-Difluoro-3,4-dimethoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL52888 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049616 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049616&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10621294 103979928 CHEMBL52888 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046487 COc1ccc(cc1OC)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H18F2O4S/c1-26-20-9-6-14(10-21(20)27-2)17-12-19(23)18(22)11-16(17)13-4-7-15(8-5-13)28(3,24)25/h4-12H,1-3H3 LTICETBYOXBZNU-UHFFFAOYSA-N 50049643 4',5'-Difluoro-4''-methanesulfonyl-3,4-dimethoxy-[1,1';2',1'']terphenyl::CHEMBL52889 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049643 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049643&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10668927 103979955 CHEMBL52889 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046488 COc1ccc(cc1C)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C20H17F2NO3S/c1-12-9-14(5-8-20(12)26-2)17-11-19(22)18(21)10-16(17)13-3-6-15(7-4-13)27(23,24)25/h3-11H,1-2H3,(H2,23,24,25) MUGCQDUJQZLPRQ-UHFFFAOYSA-N 50049656 4',5'-Difluoro-4-methoxy-3-methyl-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL51860 Prostaglandin G/H synthase 1 Homo sapiens 10900 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049656 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049656&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10834201 103979968 CHEMBL51860 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046491 NS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc(F)cc1 InChI=1S/C18H12F3NO2S/c19-13-5-1-11(2-6-13)15-9-17(20)18(21)10-16(15)12-3-7-14(8-4-12)25(22,23)24/h1-10H,(H2,22,23,24) HMKMEDJAHJBTLO-UHFFFAOYSA-N 50049659 4,4',5'-Trifluoro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::4',5',4''-Trifluoro-[1,1';2',1'']terphenyl-4-sulfonic acid amide::CHEMBL296384 Prostaglandin G/H synthase 1 Homo sapiens 5700 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049659 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049659&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10316629 103979971 CHEMBL296384 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046492 Cc1cc(ccc1F)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H15F3O2S/c1-12-9-14(5-8-18(12)21)17-11-20(23)19(22)10-16(17)13-3-6-15(7-4-13)26(2,24)25/h3-11H,1-2H3 IRTNTZQNMIEGDE-UHFFFAOYSA-N 50049623 4,4',5'-Trifluoro-4''-methanesulfonyl-3-methyl-[1,1';2',1'']terphenyl::CHEMBL443791 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049623 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049623&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10809519 103979935 CHEMBL443791 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046493 CS(=O)(=O)c1ccc(cc1)-c1cc(Cl)c(Cl)cc1-c1ccc(F)cc1 InChI=1S/C19H13Cl2FO2S/c1-25(23,24)15-8-4-13(5-9-15)17-11-19(21)18(20)10-16(17)12-2-6-14(22)7-3-12/h2-11H,1H3 ANPZZVXVQQYMAD-UHFFFAOYSA-N 50049654 4',5'-Dichloro-4''-fluoro-4-methanesulfonyl-[1,1';2',1'']terphenyl::4',5'-Dichloro-4-fluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::CHEMBL54945 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049654 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049654&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10644380 103979966 CHEMBL54945 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046494 COc1ccc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H14ClF2NO3S/c1-26-19-7-4-12(8-16(19)20)15-10-18(22)17(21)9-14(15)11-2-5-13(6-3-11)27(23,24)25/h2-10H,1H3,(H2,23,24,25) MSULOQJDYOQZPZ-UHFFFAOYSA-N 50049652 3-Chloro-4',5'-difluoro-4-methoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL55348 Prostaglandin G/H synthase 1 Homo sapiens 18900 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049652 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049652&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10179720 103979964 CHEMBL55348 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046497 COc1ccc(cc1F)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H14F3NO3S/c1-26-19-7-4-12(8-18(19)22)15-10-17(21)16(20)9-14(15)11-2-5-13(6-3-11)27(23,24)25/h2-10H,1H3,(H2,23,24,25) XYPOZNYKHAQGHD-UHFFFAOYSA-N 50049639 3,4',5'-Trifluoro-4-methoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL55072 Prostaglandin G/H synthase 1 Homo sapiens 22500 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049639 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049639&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10385880 103979951 CHEMBL55072 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046500 Cc1ccc(cc1C)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C20H17F2NO2S/c1-12-3-4-15(9-13(12)2)18-11-20(22)19(21)10-17(18)14-5-7-16(8-6-14)26(23,24)25/h3-11H,1-2H3,(H2,23,24,25) QGGGJODXPMZGCO-UHFFFAOYSA-N 50049662 4',5'-Difluoro-3,4-dimethyl-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL54326 Prostaglandin G/H synthase 1 Homo sapiens 14600 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049662 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049662&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10547351 103979974 CHEMBL54326 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046502 Cc1ccc(cn1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C18H14F2N2O2S/c1-11-2-3-13(10-22-11)16-9-18(20)17(19)8-15(16)12-4-6-14(7-5-12)25(21,23)24/h2-10H,1H3,(H2,21,23,24) NVDWWXSVMQNLOI-UHFFFAOYSA-N 50049663 4',5'-Difluoro-2'-(6-methyl-pyridin-3-yl)-biphenyl-4-sulfonic acid amide::CHEMBL292413 Prostaglandin G/H synthase 1 Homo sapiens 265000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049663 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049663&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10713528 103979975 CHEMBL292413 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046505 CS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc2OCOc2c1 InChI=1S/C20H14F2O4S/c1-27(23,24)14-5-2-12(3-6-14)15-9-17(21)18(22)10-16(15)13-4-7-19-20(8-13)26-11-25-19/h2-10H,11H2,1H3 GARKKXFHXDZJSG-UHFFFAOYSA-N 50049635 5-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-benzo[1,3]dioxole::CHEMBL416126 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049635 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049635&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10500466 103979947 CHEMBL416126 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046506 Cc1ccc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H14ClF2NO2S/c1-11-2-3-13(8-17(11)20)16-10-19(22)18(21)9-15(16)12-4-6-14(7-5-12)26(23,24)25/h2-10H,1H3,(H2,23,24,25) XSEGDVOAKVYGFX-UHFFFAOYSA-N 50049625 3-Chloro-4',5'-difluoro-4-methyl-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL54327 Prostaglandin G/H synthase 1 Homo sapiens 16500 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049625 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049625&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10644309 103979937 CHEMBL54327 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046507 NS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc(F)c(Cl)c1 InChI=1S/C18H11ClF3NO2S/c19-15-7-11(3-6-16(15)20)14-9-18(22)17(21)8-13(14)10-1-4-12(5-2-10)26(23,24)25/h1-9H,(H2,23,24,25) QZOXMKNWQZCVDE-UHFFFAOYSA-N 50049619 3-Chloro-4,4',5'-trifluoro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL52820 Prostaglandin G/H synthase 1 Homo sapiens 5500 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049619&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10046378 103979931 CHEMBL52820 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046510 CN(C)c1ccc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C20H17ClF2N2O2S/c1-25(2)20-8-5-13(9-17(20)21)16-11-19(23)18(22)10-15(16)12-3-6-14(7-4-12)28(24,26)27/h3-11H,1-2H3,(H2,24,26,27) LLUUVZZXTDQWCM-UHFFFAOYSA-N 50049646 3-Chloro-4-dimethylamino-4',5'-difluoro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL52872 Prostaglandin G/H synthase 1 Homo sapiens 590 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049646 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049646&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 9932045 103979958 CHEMBL52872 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046513 CS(=O)(=O)c1ccc(cc1)-c1cc2ccccc2cc1-c1ccc(F)cc1 InChI=1S/C23H17FO2S/c1-27(25,26)21-12-8-17(9-13-21)23-15-19-5-3-2-4-18(19)14-22(23)16-6-10-20(24)11-7-16/h2-15H,1H3 CGRVXIOZXUPGRG-UHFFFAOYSA-N 50049658 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-naphthalene::CHEMBL294650 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049658 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049658&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10762072 103979970 CHEMBL294650 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046515 Cc1c(c2cc(ccc2n1C(=O)c3ccc(cc3)Cl)OC)CC(=O)O InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 indometacin::Indocin::2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indomethacin::US9271961, Indomethacin::US11478464, Compound Indomethacin::US11786535, Compound Indomethacin Prostaglandin G/H synthase 1 Homo sapiens 100 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search IMN 1S2A,1Z9H,2BXK,2BXM,2BXQ,2DM6,2OTH,2ZB8,3ADS,3ADX,3FO7,3H1X,3IB1,3UG8,3UGR,4COX,4EIX,4IK7,4IKI,4JQ4,4KYK,4XUM,4YIA,7FCG,8XXV,8YG7,9MDF,9MDH 3715 46517802 CHEMBL6 DB00328 C01926 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046521 COc1ccc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H15ClF2O3S/c1-26-20-8-5-13(9-17(20)21)16-11-19(23)18(22)10-15(16)12-3-6-14(7-4-12)27(2,24)25/h3-11H,1-2H3 CUIDMPSXUBHFLG-UHFFFAOYSA-N 50049641 3-Chloro-4',5'-difluoro-4''-methanesulfonyl-4-methoxy-[1,1';2',1'']terphenyl::CHEMBL52019 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049641 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049641&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10716420 103979953 CHEMBL52019 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046522 CS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(Cl)cc1 InChI=1S/C19H15ClO2S/c1-23(21,22)17-12-8-15(9-13-17)19-5-3-2-4-18(19)14-6-10-16(20)11-7-14/h2-13H,1H3 XDXUQXVTDMNRFB-UHFFFAOYSA-N 50049629 4''-Chloro-4-methanesulfonyl-[1,1';2',1'']terphenyl::4''''-Chloro-4-methanesulfonyl-[1,1'';2'',1'''']terphenyl::4-Chloro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::CHEMBL55188 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049629 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049629&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10641092 103979941 CHEMBL55188 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046523 Cc1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H16F2O2S/c1-13-3-5-14(6-4-13)17-11-19(21)20(22)12-18(17)15-7-9-16(10-8-15)25(2,23)24/h3-12H,1-2H3 CFMPDXYFWIFIRY-UHFFFAOYSA-N 50049660 4',5'-Difluoro-4-methanesulfonyl-4''-methyl-[1,1';2',1'']terphenyl::4',5'-Difluoro-4''-methanesulfonyl-4-methyl-[1,1';2',1'']terphenyl::CHEMBL293771 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049660 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049660&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10832238 103979972 CHEMBL293771 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046526 Cc1ccc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H15ClF2O2S/c1-12-3-4-14(9-18(12)21)17-11-20(23)19(22)10-16(17)13-5-7-15(8-6-13)26(2,24)25/h3-11H,1-2H3 ANRYKVMKXLTRQF-UHFFFAOYSA-N 50049637 3-Chloro-4',5'-difluoro-4''-methanesulfonyl-4-methyl-[1,1';2',1'']terphenyl::CHEMBL417748 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049637 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049637&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10524587 103979949 CHEMBL417748 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046529 CS(=O)(=O)c1ccc(cc1)-c1c(F)c(F)c(F)c(F)c1-c1ccc(F)cc1 InChI=1S/C19H11F5O2S/c1-27(25,26)13-8-4-11(5-9-13)15-14(10-2-6-12(20)7-3-10)16(21)18(23)19(24)17(15)22/h2-9H,1H3 YUHFQOJMNNCUAF-UHFFFAOYSA-N 50049627 4,3',4',5',6'-Pentafluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::CHEMBL54367 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049627 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049627&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 11795129 103979939 CHEMBL54367 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046534 Cc1cc(ccc1F)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H14F3NO2S/c1-11-8-13(4-7-17(11)20)16-10-19(22)18(21)9-15(16)12-2-5-14(6-3-12)26(23,24)25/h2-10H,1H3,(H2,23,24,25) OQARYRSGLRPZDG-UHFFFAOYSA-N 50049644 4,4',5'-Trifluoro-3-methyl-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL52020 Prostaglandin G/H synthase 1 Homo sapiens 3700 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049644 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049644&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10571627 103979956 CHEMBL52020 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046535 NS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)cc1 InChI=1S/C18H14FNO2S/c19-15-9-5-13(6-10-15)17-3-1-2-4-18(17)14-7-11-16(12-8-14)23(20,21)22/h1-12H,(H2,20,21,22) JAQSXADRWSRLBT-UHFFFAOYSA-N 50049657 4''-Fluoro-[1,1';2',1'']terphenyl-4-sulfonic acid amide::4-Fluoro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::4-Fluoro-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide::CHEMBL294715 Prostaglandin G/H synthase 1 Homo sapiens 19000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049657 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049657&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10782440 103979969 CHEMBL294715 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046537 CS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc(F)cc1 InChI=1S/C19H13F3O2S/c1-25(23,24)15-8-4-13(5-9-15)17-11-19(22)18(21)10-16(17)12-2-6-14(20)7-3-12/h2-11H,1H3 HNFQHHNIJFTNOS-UHFFFAOYSA-N 50049632 4,4',5'-Trifluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::4',5',4''-Trifluoro-4-methanesulfonyl-[1,1';2',1'']terphenyl::CHEMBL442164 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049632 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049632&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10546567 103979944 CHEMBL442164 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046538 CS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc(F)c(Cl)c1 InChI=1S/C19H12ClF3O2S/c1-26(24,25)13-5-2-11(3-6-13)14-9-18(22)19(23)10-15(14)12-4-7-17(21)16(20)8-12/h2-10H,1H3 FPZPYMHOAMRFET-UHFFFAOYSA-N 50049642 3-Chloro-4,4',5'-trifluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::CHEMBL52760 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049642 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049642&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10786954 103979954 CHEMBL52760 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046539 NS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(Cl)cc1 InChI=1S/C18H14ClNO2S/c19-15-9-5-13(6-10-15)17-3-1-2-4-18(17)14-7-11-16(12-8-14)23(20,21)22/h1-12H,(H2,20,21,22) LKDQUKKEOTYRQL-UHFFFAOYSA-N 50049651 4-Chloro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::4-Chloro-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide::CHEMBL52402 Prostaglandin G/H synthase 1 Homo sapiens 3900 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049651 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049651&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10545354 103979963 CHEMBL52402 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50046540 CS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)c(Cl)c1 InChI=1S/C19H14ClFO2S/c1-24(22,23)15-9-6-13(7-10-15)16-4-2-3-5-17(16)14-8-11-19(21)18(20)12-14/h2-12H,1H3 DRLYABMZPXHNSE-UHFFFAOYSA-N 50049630 3-Chloro-4-fluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::3''''-Chloro-4''''-fluoro-4-methanesulfonyl-[1,1'';2'',1'''']terphenyl::CHEMBL52454 Prostaglandin G/H synthase 1 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049630 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7854&target=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049630&enzyme=Prostaglandin+G%2FH+synthase+1&column=ki&startPg=0&Increment=50&submit=Search 10832407 103979942 CHEMBL52454 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 6Y3C,1PTH,1PGG,1PGF,1PGE,1IGZ,1IGX,1FE2 Prostaglandin G/H synthase 1 PGH1_HUMAN P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8 50080677 COc1ccc(cc1OC)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C20H17F2NO4S/c1-26-19-8-5-13(9-20(19)27-2)16-11-18(22)17(21)10-15(16)12-3-6-14(7-4-12)28(23,24)25/h3-11H,1-2H3,(H2,23,24,25) DYBYPXGXLZNZQU-UHFFFAOYSA-N 50049616 4',5'-Difluoro-3,4-dimethoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL52888 Prostaglandin G/H synthase 2 Homo sapiens 65 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049616 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049616&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10621294 103979928 CHEMBL52888 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080678 COc1c(Cl)cc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H13Cl2F2NO3S/c1-27-19-15(20)6-11(7-16(19)21)14-9-18(23)17(22)8-13(14)10-2-4-12(5-3-10)28(24,25)26/h2-9H,1H3,(H2,24,25,26) FHVXNQKGIKQOCB-UHFFFAOYSA-N 50049621 3,5-Dichloro-4',5'-difluoro-4-methoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL300597 Prostaglandin G/H synthase 2 Homo sapiens 21 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049621 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049621&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11797537 103979933 CHEMBL300597 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080681 Cc1ccc(nc1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C18H14F2N2O2S/c1-11-2-7-18(22-10-11)15-9-17(20)16(19)8-14(15)12-3-5-13(6-4-12)25(21,23)24/h2-10H,1H3,(H2,21,23,24) ABFBGNCEKVSSJD-UHFFFAOYSA-N 50049620 4',5'-Difluoro-2'-(5-methyl-pyridin-2-yl)-biphenyl-4-sulfonic acid amide::CHEMBL54619 Prostaglandin G/H synthase 2 Homo sapiens 330 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049620 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049620&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10784741 103979932 CHEMBL54619 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080682 NS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc2OCOc2c1 InChI=1S/C19H13F2NO4S/c20-16-8-14(11-1-4-13(5-2-11)27(22,23)24)15(9-17(16)21)12-3-6-18-19(7-12)26-10-25-18/h1-9H,10H2,(H2,22,23,24) FJQRBWIOLPBVTA-UHFFFAOYSA-N 50049622 2'-Benzo[1,3]dioxol-5-yl-4',5'-difluoro-biphenyl-4-sulfonic acid amide::CHEMBL300600 Prostaglandin G/H synthase 2 Homo sapiens 4 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049622 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049622&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10524370 103979934 CHEMBL300600 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080684 Cc1cc(ccc1F)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H15F3O2S/c1-12-9-14(5-8-18(12)21)17-11-20(23)19(22)10-16(17)13-3-6-15(7-4-13)26(2,24)25/h3-11H,1-2H3 IRTNTZQNMIEGDE-UHFFFAOYSA-N 50049623 4,4',5'-Trifluoro-4''-methanesulfonyl-3-methyl-[1,1';2',1'']terphenyl::CHEMBL443791 Prostaglandin G/H synthase 2 Homo sapiens 5 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049623 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049623&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10809519 103979935 CHEMBL443791 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080688 Cc1ccc(cn1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C19H15F2NO2S/c1-12-3-4-14(11-22-12)17-10-19(21)18(20)9-16(17)13-5-7-15(8-6-13)25(2,23)24/h3-11H,1-2H3 MKFHCOCWLKUAMC-UHFFFAOYSA-N 50049628 5-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-2-methyl-pyridine::CHEMBL299251 Prostaglandin G/H synthase 2 Homo sapiens 170 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049628 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049628&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10570444 103979940 CHEMBL299251 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080689 Cc1ccc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H14ClF2NO2S/c1-11-2-3-13(8-17(11)20)16-10-19(22)18(21)9-15(16)12-4-6-14(7-5-12)26(23,24)25/h2-10H,1H3,(H2,23,24,25) XSEGDVOAKVYGFX-UHFFFAOYSA-N 50049625 3-Chloro-4',5'-difluoro-4-methyl-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL54327 Prostaglandin G/H synthase 2 Homo sapiens 3 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049625 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049625&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10644309 103979937 CHEMBL54327 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080690 CS(=O)(=O)c1ccc(cc1)-c1c(F)c(F)c(F)c(F)c1-c1ccc(F)cc1 InChI=1S/C19H11F5O2S/c1-27(25,26)13-8-4-11(5-9-13)15-14(10-2-6-12(20)7-3-10)16(21)18(23)19(24)17(15)22/h2-9H,1H3 YUHFQOJMNNCUAF-UHFFFAOYSA-N 50049627 4,3',4',5',6'-Pentafluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::CHEMBL54367 Prostaglandin G/H synthase 2 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049627 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049627&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11795129 103979939 CHEMBL54367 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080692 CS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc(F)cc1 InChI=1S/C19H13F3O2S/c1-25(23,24)15-8-4-13(5-9-15)17-11-19(22)18(21)10-16(17)12-2-6-14(20)7-3-12/h2-11H,1H3 HNFQHHNIJFTNOS-UHFFFAOYSA-N 50049632 4,4',5'-Trifluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::4',5',4''-Trifluoro-4-methanesulfonyl-[1,1';2',1'']terphenyl::CHEMBL442164 Prostaglandin G/H synthase 2 Homo sapiens 14 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049632 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049632&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10546567 103979944 CHEMBL442164 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080694 CS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc2OCOc2c1 InChI=1S/C20H14F2O4S/c1-27(23,24)14-5-2-12(3-6-14)15-9-17(21)18(22)10-16(15)13-4-7-19-20(8-13)26-11-25-19/h2-10H,11H2,1H3 GARKKXFHXDZJSG-UHFFFAOYSA-N 50049635 5-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-benzo[1,3]dioxole::CHEMBL416126 Prostaglandin G/H synthase 2 Homo sapiens 12 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049635 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049635&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10500466 103979947 CHEMBL416126 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080698 Cc1c(c2cc(ccc2n1C(=O)c3ccc(cc3)Cl)OC)CC(=O)O InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 indometacin::Indocin::2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indomethacin::US9271961, Indomethacin::US11478464, Compound Indomethacin::US11786535, Compound Indomethacin Prostaglandin G/H synthase 2 Homo sapiens 900 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 1S2A,1Z9H,2BXK,2BXM,2BXQ,2DM6,2OTH,2ZB8,3ADS,3ADX,3FO7,3H1X,3IB1,3UG8,3UGR,4COX,4EIX,4IK7,4IKI,4JQ4,4KYK,4XUM,4YIA,7FCG,8XXV,8YG7,9MDF,9MDH 3715 46517802 CHEMBL6 DB00328 C01926 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080699 Cc1ccc(nc1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C19H15F2NO2S/c1-12-3-8-19(22-11-12)16-10-18(21)17(20)9-15(16)13-4-6-14(7-5-13)25(2,23)24/h3-11H,1-2H3 YNOSXIZNGZQQRP-UHFFFAOYSA-N 50049626 2-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-5-methyl-pyridine::CHEMBL292607 Prostaglandin G/H synthase 2 Homo sapiens 52300 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049626 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049626&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10522463 103979938 CHEMBL292607 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080702 COc1ccc(cc1Cl)-c1ccccc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H17ClO3S/c1-24-20-12-9-15(13-19(20)21)18-6-4-3-5-17(18)14-7-10-16(11-8-14)25(2,22)23/h3-13H,1-2H3 KZIVRPXSIUTGGU-UHFFFAOYSA-N 50049638 3-Chloro-4''-methanesulfonyl-4-methoxy-[1,1';2',1'']terphenyl::CHEMBL299567 Prostaglandin G/H synthase 2 Homo sapiens 11400 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049638 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10667040 103979950 CHEMBL299567 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080705 COc1ccc(cc1Cl)-c1ccccc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H16ClNO3S/c1-24-19-11-8-14(12-18(19)20)17-5-3-2-4-16(17)13-6-9-15(10-7-13)25(21,22)23/h2-12H,1H3,(H2,21,22,23) YHPIWFZVGYDONZ-UHFFFAOYSA-N 50049618 3-Chloro-4-methoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::3-Chloro-4-methoxy-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide::CHEMBL54039 Prostaglandin G/H synthase 2 Homo sapiens 19 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049618 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049618&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10523413 103979930 CHEMBL54039 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080708 COc1ccc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H15ClF2O3S/c1-26-20-8-5-13(9-17(20)21)16-11-19(23)18(22)10-15(16)12-3-6-14(7-4-12)27(2,24)25/h3-11H,1-2H3 CUIDMPSXUBHFLG-UHFFFAOYSA-N 50049641 3-Chloro-4',5'-difluoro-4''-methanesulfonyl-4-methoxy-[1,1';2',1'']terphenyl::CHEMBL52019 Prostaglandin G/H synthase 2 Homo sapiens 19 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049641 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049641&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10716420 103979953 CHEMBL52019 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080710 COc1ccc(cc1OC)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H18F2O4S/c1-26-20-9-6-14(10-21(20)27-2)17-12-19(23)18(22)11-16(17)13-4-7-15(8-5-13)28(3,24)25/h4-12H,1-3H3 LTICETBYOXBZNU-UHFFFAOYSA-N 50049643 4',5'-Difluoro-4''-methanesulfonyl-3,4-dimethoxy-[1,1';2',1'']terphenyl::CHEMBL52889 Prostaglandin G/H synthase 2 Homo sapiens 340 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049643 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049643&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10668927 103979955 CHEMBL52889 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080711 Cc1cc(ccc1F)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H14F3NO2S/c1-11-8-13(4-7-17(11)20)16-10-19(22)18(21)9-15(16)12-2-5-14(6-3-12)26(23,24)25/h2-10H,1H3,(H2,23,24,25) OQARYRSGLRPZDG-UHFFFAOYSA-N 50049644 4,4',5'-Trifluoro-3-methyl-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL52020 Prostaglandin G/H synthase 2 Homo sapiens 2 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049644 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049644&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10571627 103979956 CHEMBL52020 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080713 COc1ccc(cc1F)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H15F3O3S/c1-26-20-8-5-13(9-19(20)23)16-11-18(22)17(21)10-15(16)12-3-6-14(7-4-12)27(2,24)25/h3-11H,1-2H3 DYJXKHJKHDHNON-UHFFFAOYSA-N 50049634 3,4',5'-Trifluoro-4''-methanesulfonyl-4-methoxy-[1,1';2',1'']terphenyl::CHEMBL54649 Prostaglandin G/H synthase 2 Homo sapiens 21 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049634 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049634&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10548520 103979946 CHEMBL54649 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080714 CN(C)c1ccc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C20H17ClF2N2O2S/c1-25(2)20-8-5-13(9-17(20)21)16-11-19(23)18(22)10-15(16)12-3-6-14(7-4-12)28(24,26)27/h3-11H,1-2H3,(H2,24,26,27) LLUUVZZXTDQWCM-UHFFFAOYSA-N 50049646 3-Chloro-4-dimethylamino-4',5'-difluoro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL52872 Prostaglandin G/H synthase 2 Homo sapiens 6 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049646 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049646&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9932045 103979958 CHEMBL52872 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080718 NS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc2OCCOc2c1 InChI=1S/C20H15F2NO4S/c21-17-10-15(12-1-4-14(5-2-12)28(23,24)25)16(11-18(17)22)13-3-6-19-20(9-13)27-8-7-26-19/h1-6,9-11H,7-8H2,(H2,23,24,25) RKDRZOIGQPIOJE-UHFFFAOYSA-N 50049647 2'-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-4',5'-difluoro-biphenyl-4-sulfonic acid amide::CHEMBL55395 Prostaglandin G/H synthase 2 Homo sapiens 32 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049647 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049647&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10787338 103979959 CHEMBL55395 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080719 COc1c(Cl)cc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H14Cl2F2O3S/c1-27-20-16(21)7-12(8-17(20)22)15-10-19(24)18(23)9-14(15)11-3-5-13(6-4-11)28(2,25)26/h3-10H,1-2H3 ZWAVMLHHOIMTET-UHFFFAOYSA-N 50049648 3,5-Dichloro-4',5'-difluoro-4''-methanesulfonyl-4-methoxy-[1,1';2',1'']terphenyl::CHEMBL55224 Prostaglandin G/H synthase 2 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049648 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049648&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10789363 103979960 CHEMBL55224 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080720 CN(C)c1ccc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H18ClF2NO2S/c1-25(2)21-9-6-14(10-18(21)22)17-12-20(24)19(23)11-16(17)13-4-7-15(8-5-13)28(3,26)27/h4-12H,1-3H3 QZSPOJXXPCQISC-UHFFFAOYSA-N 50049649 (3-Chloro-4',5'-difluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl-4-yl)-dimethyl-amine::CHEMBL299806 Prostaglandin G/H synthase 2 Homo sapiens 8 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049649 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049649&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10598294 103979961 CHEMBL299806 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080721 COc1ccc(cc1C)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H18F2O3S/c1-13-10-15(6-9-21(13)26-2)18-12-20(23)19(22)11-17(18)14-4-7-16(8-5-14)27(3,24)25/h4-12H,1-3H3 WYZSVZCOXZSTPN-UHFFFAOYSA-N 50049636 4',5'-Difluoro-4''-methanesulfonyl-4-methoxy-3-methyl-[1,1';2',1'']terphenyl::CHEMBL418448 Prostaglandin G/H synthase 2 Homo sapiens 13 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049636 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049636&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10739009 103979948 CHEMBL418448 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080722 CS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc(F)c(Cl)c1 InChI=1S/C19H12ClF3O2S/c1-26(24,25)13-5-2-11(3-6-13)14-9-18(22)19(23)10-15(14)12-4-7-17(21)16(20)8-12/h2-10H,1H3 FPZPYMHOAMRFET-UHFFFAOYSA-N 50049642 3-Chloro-4,4',5'-trifluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::CHEMBL52760 Prostaglandin G/H synthase 2 Homo sapiens 10 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049642 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049642&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10786954 103979954 CHEMBL52760 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080723 Cc1cc(ccc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H14ClF2NO2S/c1-11-8-13(4-7-17(11)20)16-10-19(22)18(21)9-15(16)12-2-5-14(6-3-12)26(23,24)25/h2-10H,1H3,(H2,23,24,25) QRQGMZAVXNCVOI-UHFFFAOYSA-N 50049653 4-Chloro-4',5'-difluoro-3-methyl-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL55805 Prostaglandin G/H synthase 2 Homo sapiens 3 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049653 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049653&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10810604 103979965 CHEMBL55805 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080725 Cc1cc(ccc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H15ClF2O2S/c1-12-9-14(5-8-18(12)21)17-11-20(23)19(22)10-16(17)13-3-6-15(7-4-13)26(2,24)25/h3-11H,1-2H3 SXRSLXYKFPVRRL-UHFFFAOYSA-N 50049617 4-Chloro-4',5'-difluoro-4''-methanesulfonyl-3-methyl-[1,1';2',1'']terphenyl::CHEMBL57837 Prostaglandin G/H synthase 2 Homo sapiens 6 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049617 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049617&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10572620 103979929 CHEMBL57837 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080727 CS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(Cl)cc1 InChI=1S/C19H15ClO2S/c1-23(21,22)17-12-8-15(9-13-17)19-5-3-2-4-18(19)14-6-10-16(20)11-7-14/h2-13H,1H3 XDXUQXVTDMNRFB-UHFFFAOYSA-N 50049629 4''-Chloro-4-methanesulfonyl-[1,1';2',1'']terphenyl::4''''-Chloro-4-methanesulfonyl-[1,1'';2'',1'''']terphenyl::4-Chloro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::CHEMBL55188 Prostaglandin G/H synthase 2 Homo sapiens 140 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049629 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049629&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10641092 103979941 CHEMBL55188 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080728 CS(=O)(=O)c1ccc(cc1)-c1cc2OCOc2cc1-c1ccc(F)cc1 InChI=1S/C20H15FO4S/c1-26(22,23)16-8-4-14(5-9-16)18-11-20-19(24-12-25-20)10-17(18)13-2-6-15(21)7-3-13/h2-11H,12H2,1H3 SIGUPSKJHJMMAX-UHFFFAOYSA-N 50049650 5-(4-Fluoro-phenyl)-6-(4-methanesulfonyl-phenyl)-benzo[1,3]dioxole::CHEMBL298729 Prostaglandin G/H synthase 2 Homo sapiens 83 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049650 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049650&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10761664 103979962 CHEMBL298729 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080729 NS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(Cl)cc1 InChI=1S/C18H14ClNO2S/c19-15-9-5-13(6-10-15)17-3-1-2-4-18(17)14-7-11-16(12-8-14)23(20,21)22/h1-12H,(H2,20,21,22) LKDQUKKEOTYRQL-UHFFFAOYSA-N 50049651 4-Chloro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::4-Chloro-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide::CHEMBL52402 Prostaglandin G/H synthase 2 Homo sapiens 6 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049651 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049651&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10545354 103979963 CHEMBL52402 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080730 COc1ccc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H14ClF2NO3S/c1-26-19-7-4-12(8-16(19)20)15-10-18(22)17(21)9-14(15)11-2-5-13(6-3-11)27(23,24)25/h2-10H,1H3,(H2,23,24,25) MSULOQJDYOQZPZ-UHFFFAOYSA-N 50049652 3-Chloro-4',5'-difluoro-4-methoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL55348 Prostaglandin G/H synthase 2 Homo sapiens 13 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049652 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049652&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10179720 103979964 CHEMBL55348 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080734 COc1ccc(cc1C)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C20H17F2NO3S/c1-12-9-14(5-8-20(12)26-2)17-11-19(22)18(21)10-16(17)13-3-6-15(7-4-13)27(23,24)25/h3-11H,1-2H3,(H2,23,24,25) MUGCQDUJQZLPRQ-UHFFFAOYSA-N 50049656 4',5'-Difluoro-4-methoxy-3-methyl-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL51860 Prostaglandin G/H synthase 2 Homo sapiens 5 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049656 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049656&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10834201 103979968 CHEMBL51860 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080735 Cc1ccc(cc1C)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H18F2O2S/c1-13-4-5-16(10-14(13)2)19-12-21(23)20(22)11-18(19)15-6-8-17(9-7-15)26(3,24)25/h4-12H,1-3H3 XUKVJQAMNLZRMM-UHFFFAOYSA-N 50049640 4',5'-Difluoro-4''-methanesulfonyl-3,4-dimethyl-[1,1';2',1'']terphenyl::CHEMBL300601 Prostaglandin G/H synthase 2 Homo sapiens 23 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049640 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049640&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10595453 103979952 CHEMBL300601 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080736 CS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc2OCCOc2c1 InChI=1S/C21H16F2O4S/c1-28(24,25)15-5-2-13(3-6-15)16-11-18(22)19(23)12-17(16)14-4-7-20-21(10-14)27-9-8-26-20/h2-7,10-12H,8-9H2,1H3 DLEXWYPUXDTMQV-UHFFFAOYSA-N 50049624 6-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-2,3-dihydro-benzo[1,4]dioxine::CHEMBL54746 Prostaglandin G/H synthase 2 Homo sapiens 340 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049624 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049624&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10597216 103979936 CHEMBL54746 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080738 NS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)cc1 InChI=1S/C18H14FNO2S/c19-15-9-5-13(6-10-15)17-3-1-2-4-18(17)14-7-11-16(12-8-14)23(20,21)22/h1-12H,(H2,20,21,22) JAQSXADRWSRLBT-UHFFFAOYSA-N 50049657 4''-Fluoro-[1,1';2',1'']terphenyl-4-sulfonic acid amide::4-Fluoro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::4-Fluoro-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide::CHEMBL294715 Prostaglandin G/H synthase 2 Homo sapiens 61 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049657 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049657&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10782440 103979969 CHEMBL294715 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080740 NS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc(F)c(Cl)c1 InChI=1S/C18H11ClF3NO2S/c19-15-7-11(3-6-16(15)20)14-9-18(22)17(21)8-13(14)10-1-4-12(5-2-10)26(23,24)25/h1-9H,(H2,23,24,25) QZOXMKNWQZCVDE-UHFFFAOYSA-N 50049619 3-Chloro-4,4',5'-trifluoro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL52820 Prostaglandin G/H synthase 2 Homo sapiens 2 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049619&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10046378 103979931 CHEMBL52820 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080745 Cc1ccc(cc1C)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C20H17F2NO2S/c1-12-3-4-15(9-13(12)2)18-11-20(22)19(21)10-17(18)14-5-7-16(8-6-14)26(23,24)25/h3-11H,1-2H3,(H2,23,24,25) QGGGJODXPMZGCO-UHFFFAOYSA-N 50049662 4',5'-Difluoro-3,4-dimethyl-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL54326 Prostaglandin G/H synthase 2 Homo sapiens 5 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049662 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049662&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10547351 103979974 CHEMBL54326 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080748 CS(=O)(=O)c1ccc(cc1)-c1cc(Cl)c(Cl)cc1-c1ccc(F)cc1 InChI=1S/C19H13Cl2FO2S/c1-25(23,24)15-8-4-13(5-9-15)17-11-19(21)18(20)10-16(17)12-2-6-14(22)7-3-12/h2-11H,1H3 ANPZZVXVQQYMAD-UHFFFAOYSA-N 50049654 4',5'-Dichloro-4''-fluoro-4-methanesulfonyl-[1,1';2',1'']terphenyl::4',5'-Dichloro-4-fluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::CHEMBL54945 Prostaglandin G/H synthase 2 Homo sapiens 240 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049654 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049654&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10644380 103979966 CHEMBL54945 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080749 Cc1ccc(cc1Cl)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H15ClF2O2S/c1-12-3-4-14(9-18(12)21)17-11-20(23)19(22)10-16(17)13-5-7-15(8-6-13)26(2,24)25/h3-11H,1-2H3 ANRYKVMKXLTRQF-UHFFFAOYSA-N 50049637 3-Chloro-4',5'-difluoro-4''-methanesulfonyl-4-methyl-[1,1';2',1'']terphenyl::CHEMBL417748 Prostaglandin G/H synthase 2 Homo sapiens 13 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049637 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049637&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10524587 103979949 CHEMBL417748 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080751 COc1ccc(cc1F)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H14F3NO3S/c1-26-19-7-4-12(8-18(19)22)15-10-17(21)16(20)9-14(15)11-2-5-13(6-3-11)27(23,24)25/h2-10H,1H3,(H2,23,24,25) XYPOZNYKHAQGHD-UHFFFAOYSA-N 50049639 3,4',5'-Trifluoro-4-methoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL55072 Prostaglandin G/H synthase 2 Homo sapiens 13 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049639 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10385880 103979951 CHEMBL55072 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080752 CS(=O)(=O)c1ccc(cc1)-c1cc2ccccc2cc1-c1ccc(F)cc1 InChI=1S/C23H17FO2S/c1-27(25,26)21-12-8-17(9-13-21)23-15-19-5-3-2-4-18(19)14-22(23)16-6-10-20(24)11-7-16/h2-15H,1H3 CGRVXIOZXUPGRG-UHFFFAOYSA-N 50049658 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-naphthalene::CHEMBL294650 Prostaglandin G/H synthase 2 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049658 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049658&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10762072 103979970 CHEMBL294650 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080754 NS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc(F)cc1 InChI=1S/C18H12F3NO2S/c19-13-5-1-11(2-6-13)15-9-17(20)18(21)10-16(15)12-3-7-14(8-4-12)25(22,23)24/h1-10H,(H2,22,23,24) HMKMEDJAHJBTLO-UHFFFAOYSA-N 50049659 4,4',5'-Trifluoro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::4',5',4''-Trifluoro-[1,1';2',1'']terphenyl-4-sulfonic acid amide::CHEMBL296384 Prostaglandin G/H synthase 2 Homo sapiens 4 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049659 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049659&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10316629 103979971 CHEMBL296384 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080755 CS(=O)(=O)c1ccc(cc1)-c1nccnc1-c1ccc(F)cc1 InChI=1S/C17H13FN2O2S/c1-23(21,22)15-8-4-13(5-9-15)17-16(19-10-11-20-17)12-2-6-14(18)7-3-12/h2-11H,1H3 KISKVCPIJSLUGE-UHFFFAOYSA-N 50049655 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazine::CHEMBL55189 Prostaglandin G/H synthase 2 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049655 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049655&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10735037 103979967 CHEMBL55189 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080759 CS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)cc1 InChI=1S/C19H15FO2S/c1-23(21,22)17-12-8-15(9-13-17)19-5-3-2-4-18(19)14-6-10-16(20)11-7-14/h2-13H,1H3 RFPZMXMBYMEQHZ-UHFFFAOYSA-N 50049631 4-Fluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::4''-Fluoro-4-methanesulfonyl-[1,1';2',1'']terphenyl::4''''-Fluoro-4-methanesulfonyl-[1,1'';2'',1'''']terphenyl::CHEMBL291912 Prostaglandin G/H synthase 2 Homo sapiens 260 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049631 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049631&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9905412 103979943 CHEMBL291912 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080760 COc1ccc(cc1F)-c1ccccc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H17FO3S/c1-24-20-12-9-15(13-19(20)21)18-6-4-3-5-17(18)14-7-10-16(11-8-14)25(2,22)23/h3-13H,1-2H3 ODBSRLCISKGYTE-UHFFFAOYSA-N 50049664 3-Fluoro-4''-methanesulfonyl-4-methoxy-[1,1';2',1'']terphenyl::CHEMBL54605 Prostaglandin G/H synthase 2 Homo sapiens >100000 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049664 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049664&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10546170 103979976 CHEMBL54605 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080761 Cc1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H15F2NO2S/c1-12-2-4-13(5-3-12)16-10-18(20)19(21)11-17(16)14-6-8-15(9-7-14)25(22,23)24/h2-11H,1H3,(H2,22,23,24) IEPVUPAKSGZBAR-UHFFFAOYSA-N 50049645 4',5'-Difluoro-4-methyl-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::4',5'-Difluoro-4''-methyl-[1,1';2',1'']terphenyl-4-sulfonic acid amide::CHEMBL54370 Prostaglandin G/H synthase 2 Homo sapiens 4 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049645 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049645&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10666170 103979957 CHEMBL54370 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080764 CS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)c(Cl)c1 InChI=1S/C19H14ClFO2S/c1-24(22,23)15-9-6-13(7-10-15)16-4-2-3-5-17(16)14-8-11-19(21)18(20)12-14/h2-12H,1H3 DRLYABMZPXHNSE-UHFFFAOYSA-N 50049630 3-Chloro-4-fluoro-4''-methanesulfonyl-[1,1';2',1'']terphenyl::3''''-Chloro-4''''-fluoro-4-methanesulfonyl-[1,1'';2'',1'''']terphenyl::CHEMBL52454 Prostaglandin G/H synthase 2 Homo sapiens 360 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049630 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049630&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10832407 103979942 CHEMBL52454 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080765 NS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)c(Cl)c1 InChI=1S/C18H13ClFNO2S/c19-17-11-13(7-10-18(17)20)16-4-2-1-3-15(16)12-5-8-14(9-6-12)24(21,22)23/h1-11H,(H2,21,22,23) BRWDKJBTMKFKLU-UHFFFAOYSA-N 50049633 3-Chloro-4-fluoro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::3-Chloro-4-fluoro-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide::CHEMBL54412 Prostaglandin G/H synthase 2 Homo sapiens 17 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049633 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049633&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10784838 103979945 CHEMBL54412 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080767 Cc1ccc(cn1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C18H14F2N2O2S/c1-11-2-3-13(10-22-11)16-9-18(20)17(19)8-15(16)12-4-6-14(7-5-12)25(21,23)24/h2-10H,1H3,(H2,21,23,24) NVDWWXSVMQNLOI-UHFFFAOYSA-N 50049663 4',5'-Difluoro-2'-(6-methyl-pyridin-3-yl)-biphenyl-4-sulfonic acid amide::CHEMBL292413 Prostaglandin G/H synthase 2 Homo sapiens 51 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049663 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049663&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10713528 103979975 CHEMBL292413 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080769 COc1ccc(cc1F)-c1ccccc1-c1ccc(cc1)S(N)(=O)=O InChI=1S/C19H16FNO3S/c1-24-19-11-8-14(12-18(19)20)17-5-3-2-4-16(17)13-6-9-15(10-7-13)25(21,22)23/h2-12H,1H3,(H2,21,22,23) VLZYADILQZRSFD-UHFFFAOYSA-N 50049661 3''''-Fluoro-4''''-methoxy-[1,1'';2'',1'''']terphenyl-4-sulfonic acid amide::3-Fluoro-4-methoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL442166 Prostaglandin G/H synthase 2 Homo sapiens 33 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049661 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049661&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10808251 103979973 CHEMBL442166 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876 50080774 Cc1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H16F2O2S/c1-13-3-5-14(6-4-13)17-11-19(21)20(22)12-18(17)15-7-9-16(10-8-15)25(2,23)24/h3-12H,1-2H3 CFMPDXYFWIFIRY-UHFFFAOYSA-N 50049660 4',5'-Difluoro-4-methanesulfonyl-4''-methyl-[1,1';2',1'']terphenyl::4',5'-Difluoro-4''-methanesulfonyl-4-methyl-[1,1';2',1'']terphenyl::CHEMBL293771 Prostaglandin G/H synthase 2 Homo sapiens 7.0 ChEMBL 10.1021/jm950878e 10.7270/Q2Z89BGW 8627608 Li, JJ; Norton, MB; Reinhard, EJ; Anderson, GD; Gregory, SA; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Zhang, Y; Zweifel, BS; Reitz, DB 6/25/1996 11/10/2009 Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049660 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2262&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049660&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10832238 103979972 CHEMBL293771 1 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL 5F1A,5IKV,5IKT,5IKR,5IKQ,5F19,3MDL,4PH9 Prostaglandin G/H synthase 2 PGH2_HUMAN P35354 A8K802 Q16876