BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50086833 CCOc1ccc(cc1OCC)C(CC(N)=O)N1C(=O)c2ccccc2C1=O InChI=1S/C21H22N2O5/c1-3-27-17-10-9-13(11-18(17)28-4-2)16(12-19(22)24)23-20(25)14-7-5-6-8-15(14)21(23)26/h5-11,16H,3-4,12H2,1-2H3,(H2,22,24) WTGUYKUCSLEJTB-UHFFFAOYSA-N 50052595 3-(3,4-Diethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionamide::CHEMBL322553 Tumor necrosis factor Homo sapiens 5600 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052595 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052595&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10091288 103949436 CHEMBL322553 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086834 COC(=O)CC(N1C(=O)c2ccccc2C1=O)c1ccc(OC)c(OC)c1 InChI=1S/C20H19NO6/c1-25-16-9-8-12(10-17(16)26-2)15(11-18(22)27-3)21-19(23)13-6-4-5-7-14(13)20(21)24/h4-10,15H,11H2,1-3H3 GHTLZEXBRLQMFS-UHFFFAOYSA-N 50052596 3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionic acid methyl ester::CHEMBL88935 Tumor necrosis factor Homo sapiens 2900 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052596 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052596&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 461664 103949437 CHEMBL88935 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086835 NC(=O)CC(N1C(=O)c2ccccc2C1=O)c1cccc(c1)C#N InChI=1S/C18H13N3O3/c19-10-11-4-3-5-12(8-11)15(9-16(20)22)21-17(23)13-6-1-2-7-14(13)18(21)24/h1-8,15H,9H2,(H2,20,22) WMITULKCXUQAJI-UHFFFAOYSA-N 50052597 3-(3-Cyano-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionamide::CHEMBL321032 Tumor necrosis factor Homo sapiens 89000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052597 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052597&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10687089 103949438 CHEMBL321032 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086836 COc1ccc(cc1OC)C(CC(=O)NCc1ccccc1)N1C(=O)c2ccccc2C1=O InChI=1S/C26H24N2O5/c1-32-22-13-12-18(14-23(22)33-2)21(15-24(29)27-16-17-8-4-3-5-9-17)28-25(30)19-10-6-7-11-20(19)26(28)31/h3-14,21H,15-16H2,1-2H3,(H,27,29) JWEDWYXWMXOFMA-UHFFFAOYSA-N 50052598 N-Benzyl-3-(3,4-dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionamide::CHEMBL109264 Tumor necrosis factor Homo sapiens 84000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052598 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052598&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10694592 103949439 CHEMBL109264 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086837 COc1ccc(cc1OC)C(CC(N)=O)N1C(=O)c2ccccc2C1=O InChI=1S/C19H18N2O5/c1-25-15-8-7-11(9-16(15)26-2)14(10-17(20)22)21-18(23)12-5-3-4-6-13(12)19(21)24/h3-9,14H,10H2,1-2H3,(H2,20,22) GKPXSGPDRIUIAD-UHFFFAOYSA-N 50052599 3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionamide::CHEMBL89890 Tumor necrosis factor Homo sapiens 12000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052599 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052599&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 461663 103949440 CHEMBL89890 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086838 COc1ccc(cc1)C(CC(N)=O)N1C(=O)c2ccccc2C1=O InChI=1S/C18H16N2O4/c1-24-12-8-6-11(7-9-12)15(10-16(19)21)20-17(22)13-4-2-3-5-14(13)18(20)23/h2-9,15H,10H2,1H3,(H2,19,21) HYAWNYVAQOMCFV-UHFFFAOYSA-N 50052603 3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-(4-methoxy-phenyl)-propionamide::CHEMBL111973 Tumor necrosis factor Homo sapiens 62000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052603 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052603&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 9949152 103949444 CHEMBL111973 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086839 COc1cccc(c1)C(CC(N)=O)N1C(=O)c2ccccc2C1=O InChI=1S/C18H16N2O4/c1-24-12-6-4-5-11(9-12)15(10-16(19)21)20-17(22)13-7-2-3-8-14(13)18(20)23/h2-9,15H,10H2,1H3,(H2,19,21) UMSVYDKBGARKHA-UHFFFAOYSA-N 50052601 3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-methoxy-phenyl)-propionamide::CHEMBL111637 Tumor necrosis factor Homo sapiens 120000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052601 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052601&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 9840218 103949442 CHEMBL111637 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086840 COC(=O)CC(N1C(=O)c2cccc(N)c2C1=O)c1ccc(OC)c(OC)c1 InChI=1S/C20H20N2O6/c1-26-15-8-7-11(9-16(15)27-2)14(10-17(23)28-3)22-19(24)12-5-4-6-13(21)18(12)20(22)25/h4-9,14H,10,21H2,1-3H3 UHHZKWNCNDFRNB-UHFFFAOYSA-N 50052602 3-(4-Amino-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3,4-dimethoxy-phenyl)-propionic acid methyl ester::CHEMBL110421 Tumor necrosis factor Homo sapiens 450 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052602 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052602&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10452587 103949443 CHEMBL110421 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086841 COC(=O)CC(N1C(=O)c2cc(Cl)c(Cl)cc2C1=O)c1ccc(OC)c(OC)c1 InChI=1S/C20H17Cl2NO6/c1-27-16-5-4-10(6-17(16)28-2)15(9-18(24)29-3)23-19(25)11-7-13(21)14(22)8-12(11)20(23)26/h4-8,15H,9H2,1-3H3 JYFJNGGUSZMKLR-UHFFFAOYSA-N 50052600 3-(5,6-Dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3,4-dimethoxy-phenyl)-propionic acid methyl ester::CHEMBL418836 Tumor necrosis factor Homo sapiens 13000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052600 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052600&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10694297 103949441 CHEMBL418836 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086842 COC(=O)CC(N1C(=O)c2cccc(c2C1=O)[N+]([O-])=O)c1ccc(OC)c(OC)c1 InChI=1S/C20H18N2O8/c1-28-15-8-7-11(9-16(15)29-2)14(10-17(23)30-3)21-19(24)12-5-4-6-13(22(26)27)18(12)20(21)25/h4-9,14H,10H2,1-3H3 CTNMKDMXDXFPNV-UHFFFAOYSA-N 50052604 3-(3,4-Dimethoxy-phenyl)-3-(4-nitro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionic acid methyl ester::CHEMBL327083 Tumor necrosis factor Homo sapiens 64000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052604 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052604&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10764262 103949445 CHEMBL327083 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086843 COC(=O)CC(N1C(=O)c2ccc(cc2C1=O)C(C)(C)C)c1ccc(OC)c(OC)c1 InChI=1S/C24H27NO6/c1-24(2,3)15-8-9-16-17(12-15)23(28)25(22(16)27)18(13-21(26)31-6)14-7-10-19(29-4)20(11-14)30-5/h7-12,18H,13H2,1-6H3 NUZQPRQYMWOVKN-UHFFFAOYSA-N 50052605 3-(5-tert-Butyl-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3,4-dimethoxy-phenyl)-propionic acid methyl ester::CHEMBL111111 Tumor necrosis factor Homo sapiens 4200 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052605 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052605&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10836140 103949446 CHEMBL111111 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086844 CCCOc1ccc(cc1OCCC)C(CC(N)=O)N1C(=O)c2ccccc2C1=O InChI=1S/C23H26N2O5/c1-3-11-29-19-10-9-15(13-20(19)30-12-4-2)18(14-21(24)26)25-22(27)16-7-5-6-8-17(16)23(25)28/h5-10,13,18H,3-4,11-12,14H2,1-2H3,(H2,24,26) XIMOSWSBTHUBTM-UHFFFAOYSA-N 50052607 3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-(3,4-dipropoxy-phenyl)-propionamide::CHEMBL110949 Tumor necrosis factor Homo sapiens 55000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052607 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052607&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10573618 103949448 CHEMBL110949 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086845 CNC(=O)CC(N1C(=O)c2ccccc2C1=O)c1ccc(OC)c(OC)c1 InChI=1S/C20H20N2O5/c1-21-18(23)11-15(12-8-9-16(26-2)17(10-12)27-3)22-19(24)13-6-4-5-7-14(13)20(22)25/h4-10,15H,11H2,1-3H3,(H,21,23) USPASZMTYOACPK-UHFFFAOYSA-N 50052606 3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-N-methyl-propionamide::CHEMBL111560 Tumor necrosis factor Homo sapiens 12000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052606 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052606&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10571036 103949447 CHEMBL111560 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086846 COC(=O)CC(N1C(=O)c2cc3ccccc3cc2C1=O)c1ccc(OC)c(OC)c1 InChI=1S/C24H21NO6/c1-29-20-9-8-16(12-21(20)30-2)19(13-22(26)31-3)25-23(27)17-10-14-6-4-5-7-15(14)11-18(17)24(25)28/h4-12,19H,13H2,1-3H3 CRCKHUCOOURRKN-UHFFFAOYSA-N 50052608 3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-benzo[f]isoindol-2-yl)-propionic acid methyl ester::CHEMBL110956 Tumor necrosis factor Homo sapiens 4700 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052608 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052608&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10812014 103949449 CHEMBL110956 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086847 CCNC(=O)CC(N1C(=O)c2ccccc2C1=O)c1ccc(OC)c(OC)c1 InChI=1S/C21H22N2O5/c1-4-22-19(24)12-16(13-9-10-17(27-2)18(11-13)28-3)23-20(25)14-7-5-6-8-15(14)21(23)26/h5-11,16H,4,12H2,1-3H3,(H,22,24) VIFLRPYPHOYEOY-UHFFFAOYSA-N 50052610 3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-N-ethyl-propionamide::CHEMBL111503 Tumor necrosis factor Homo sapiens 53000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052610 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052610&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10619896 103949451 CHEMBL111503 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086848 COc1ccc(cc1OC)C(CCO)N1C(=O)c2ccccc2C1=O InChI=1S/C19H19NO5/c1-24-16-8-7-12(11-17(16)25-2)15(9-10-21)20-18(22)13-5-3-4-6-14(13)19(20)23/h3-8,11,15,21H,9-10H2,1-2H3 NTWLARBDJFXJNZ-UHFFFAOYSA-N 50052611 2-[1-(3,4-Dimethoxy-phenyl)-3-hydroxy-propyl]-isoindole-1,3-dione::CHEMBL110110 Tumor necrosis factor Homo sapiens 7500 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052611 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052611&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 9840925 103949452 CHEMBL110110 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086849 NC(=O)CC(N1C(=O)c2ccccc2C1=O)c1ccc2ccccc2c1 InChI=1S/C21H16N2O3/c22-19(24)12-18(15-10-9-13-5-1-2-6-14(13)11-15)23-20(25)16-7-3-4-8-17(16)21(23)26/h1-11,18H,12H2,(H2,22,24) DRHOOZJDKQHCEL-UHFFFAOYSA-N 50052609 3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-naphthalen-2-yl-propionamide::CHEMBL323009 Tumor necrosis factor Homo sapiens 51000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052609 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052609&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 9841064 103949450 CHEMBL323009 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086850 NC(=O)CC(N1C(=O)c2ccccc2C1=O)c1ccc(cc1)C#N InChI=1S/C18H13N3O3/c19-10-11-5-7-12(8-6-11)15(9-16(20)22)21-17(23)13-3-1-2-4-14(13)18(21)24/h1-8,15H,9H2,(H2,20,22) VPJCFBWLVYCZOX-UHFFFAOYSA-N 50052614 3-(4-Cyano-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionamide::CHEMBL110972 Tumor necrosis factor Homo sapiens 150000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052614 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052614&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 9797095 103949455 CHEMBL110972 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086851 COC(=O)CC(N1C(=O)c2ccc(cc2C1=O)[N+]([O-])=O)c1ccc(OC)c(OC)c1 InChI=1S/C20H18N2O8/c1-28-16-7-4-11(8-17(16)29-2)15(10-18(23)30-3)21-19(24)13-6-5-12(22(26)27)9-14(13)20(21)25/h4-9,15H,10H2,1-3H3 RVAVIVFISJENMD-UHFFFAOYSA-N 50052615 3-(3,4-Dimethoxy-phenyl)-3-(5-nitro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionic acid methyl ester::CHEMBL322814 Tumor necrosis factor Homo sapiens 34000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052615 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052615&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10669458 103949456 CHEMBL322814 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086852 COC(=O)CC(N1C(=O)c2c(C1=O)c(Cl)ccc2Cl)c1ccc(OC)c(OC)c1 InChI=1S/C20H17Cl2NO6/c1-27-14-7-4-10(8-15(14)28-2)13(9-16(24)29-3)23-19(25)17-11(21)5-6-12(22)18(17)20(23)26/h4-8,13H,9H2,1-3H3 OQKIQDAOUNDFRS-UHFFFAOYSA-N 50052613 3-(4,7-Dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3,4-dimethoxy-phenyl)-propionic acid methyl ester::CHEMBL111544 Tumor necrosis factor Homo sapiens 7900 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052613 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052613&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10765443 103949454 CHEMBL111544 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086853 COC(=O)CC(N1C(=O)c2ccc(N)cc2C1=O)c1ccc(OC)c(OC)c1 InChI=1S/C20H20N2O6/c1-26-16-7-4-11(8-17(16)27-2)15(10-18(23)28-3)22-19(24)13-6-5-12(21)9-14(13)20(22)25/h4-9,15H,10,21H2,1-3H3 RPOHNDGOZDRWKA-UHFFFAOYSA-N 50052612 3-(5-Amino-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3,4-dimethoxy-phenyl)-propionic acid methyl ester::CHEMBL114343 Tumor necrosis factor Homo sapiens 380 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052612 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052612&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 461666 103949453 CHEMBL114343 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086854 COc1ccc(cc1OC)C(CC(O)=O)N1C(=O)c2ccccc2C1=O InChI=1S/C19H17NO6/c1-25-15-8-7-11(9-16(15)26-2)14(10-17(21)22)20-18(23)12-5-3-4-6-13(12)19(20)24/h3-9,14H,10H2,1-2H3,(H,21,22) WXRGZYUMDIVFNG-UHFFFAOYSA-N 50052618 3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionic acid::CHEMBL109316 Tumor necrosis factor Homo sapiens 60000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052618 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052618&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10360825 103949459 CHEMBL109316 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086855 COc1cc(OC)cc(c1)C(CC(N)=O)N1C(=O)c2ccccc2C1=O InChI=1S/C19H18N2O5/c1-25-12-7-11(8-13(9-12)26-2)16(10-17(20)22)21-18(23)14-5-3-4-6-15(14)19(21)24/h3-9,16H,10H2,1-2H3,(H2,20,22) KPCSISQFPQWXTP-UHFFFAOYSA-N 50052617 3-(3,5-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionamide::CHEMBL419204 Tumor necrosis factor Homo sapiens 39000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052617 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052617&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10570106 103949458 CHEMBL419204 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086856 NC(=O)CC(N1C(=O)c2ccccc2C1=O)c1ccc(Cl)c(Cl)c1 InChI=1S/C17H12Cl2N2O3/c18-12-6-5-9(7-13(12)19)14(8-15(20)22)21-16(23)10-3-1-2-4-11(10)17(21)24/h1-7,14H,8H2,(H2,20,22) KKDBECFBNZZIPX-UHFFFAOYSA-N 50052616 3-(3,4-Dichloro-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionamide::CHEMBL320347 Tumor necrosis factor Homo sapiens 70000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052616 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052616&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 9907022 103949457 CHEMBL320347 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086857 COC(=O)CC(N1C(=O)c2cccc(O)c2C1=O)c1ccc(OC)c(OC)c1 InChI=1S/C20H19NO7/c1-26-15-8-7-11(9-16(15)27-2)13(10-17(23)28-3)21-19(24)12-5-4-6-14(22)18(12)20(21)25/h4-9,13,22H,10H2,1-3H3 ITXQTSIKZWXBOQ-UHFFFAOYSA-N 50052619 3-(3,4-Dimethoxy-phenyl)-3-(4-hydroxy-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionic acid methyl ester::CHEMBL113442 Tumor necrosis factor Homo sapiens 15000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052619&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 10572133 103949460 CHEMBL113442 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3 50086858 NC(=O)CC(N1C(=O)c2ccccc2C1=O)c1ccccc1 InChI=1S/C17H14N2O3/c18-15(20)10-14(11-6-2-1-3-7-11)19-16(21)12-8-4-5-9-13(12)17(19)22/h1-9,14H,10H2,(H2,18,20) ZJZWDDCSXLSDJG-UHFFFAOYSA-N 50052620 3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionamide::CHEMBL320567 Tumor necrosis factor Homo sapiens 260000 ChEMBL 10.1021/jm9603328 10.7270/Q2V40T9Q 8765505 Muller, GW; Corral, LG; Shire, MG; Wang, H; Moreira, A; Kaplan, G; Stirling, DI 9/26/1996 11/10/2009 Celgene http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052620 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5625&target=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052620&enzyme=Tumor+necrosis+factor&column=ki&startPg=0&Increment=50&submit=Search 461665 103949461 CHEMBL320567 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 5MU8,9OK6,9OJY,9OJS,9OJO,6X86,6X85,6X83,6X82,6X81,5YOY,7JRA,9BN7,8Z8M,6OOZ,6OOY,5WUX,5M2M,5M2J,5M2I,4TWT,4G3Y,9DJW,3IT8,3ALQ,3L9J,2AZ5,7ASY,7QLF Tumor necrosis factor TNFA_HUMAN P01375 O43647 Q9P1Q2 Q9UIV3