BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50090523 CCCC(CCC)C(=O)N[C@@H](CC(=O)OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C=O InChI=1S/C24H42N6O6/c1-4-8-16(9-5-2)21(33)29-18(14-20(32)36-3)23(35)30-13-7-11-19(30)22(34)28-17(15-31)10-6-12-27-24(25)26/h15-19H,4-14H2,1-3H3,(H,28,34)(H,29,33)(H4,25,26,27) ICMSWQUELAGTTR-UHFFFAOYSA-N 50054482 (S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-4-oxo-3-(2-propyl-pentanoylamino)-butyric acid methyl ester::CHEMBL141676 Coagulation factor X Homo sapiens 301 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054482 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054482&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 9806376 103951090 CHEMBL141676 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50090524 CCCC(CCC)C(=O)N[C@@H](CC(=O)OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1CCCN(C1)C(N)=N)C=O InChI=1S/C27H46N6O6/c1-4-8-19(9-5-2)24(36)31-21(15-23(35)39-3)26(38)33-13-7-11-22(33)25(37)30-20(17-34)14-18-10-6-12-32(16-18)27(28)29/h17-22H,4-16H2,1-3H3,(H3,28,29)(H,30,37)(H,31,36) HLEXEFPWIXSUIV-UHFFFAOYSA-N 50054483 (S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethylcarbamoyl]-pyrrolidin-1-yl}-4-oxo-3-(2-propyl-pentanoylamino)-butyric acid methyl ester::CHEMBL342838 Coagulation factor X Homo sapiens >2500 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054483 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054483&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 10325271 103951091 CHEMBL342838 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50090525 NC(=N)NCCC[C@H](NC(=O)CN1CCCC[C@H](NS(=O)(=O)Cc2ccccc2)C1=O)C=O InChI=1S/C21H32N6O5S/c22-21(23)24-11-6-9-17(14-28)25-19(29)13-27-12-5-4-10-18(20(27)30)26-33(31,32)15-16-7-2-1-3-8-16/h1-3,7-8,14,17-18,26H,4-6,9-13,15H2,(H,25,29)(H4,22,23,24) PTYYNQHOHSWREY-UHFFFAOYSA-N 50054484 CVS-1778::N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-azepan-1-yl)-acetamide::CHEMBL344204 Coagulation factor X Homo sapiens 20.6 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054484 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054484&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 9891337 103951092 CHEMBL344204 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50090526 NC(=N)N1CCC[C@H](C[C@H](NC(=O)CN2CCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C=O)C1 InChI=1S/C23H34N6O5S/c24-23(25)29-11-4-8-18(13-29)12-19(15-30)26-21(31)14-28-10-5-9-20(22(28)32)27-35(33,34)16-17-6-2-1-3-7-17/h1-3,6-7,15,18-20,27H,4-5,8-14,16H2,(H3,24,25)(H,26,31) DATYERRDSFNBDN-UHFFFAOYSA-N 50054485 N-[(S)-1-((R)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide::CHEMBL342604 Prothrombin Homo sapiens 28.8 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054485 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054485&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search 10006399 103951093 CHEMBL342604 1 MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU Prothrombin THRB_HUMAN P00734 B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1 50090527 NC(=N)N1CCC[C@H](C[C@H](NC(=O)CN2CCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C=O)C1 InChI=1S/C23H34N6O5S/c24-23(25)29-11-4-8-18(13-29)12-19(15-30)26-21(31)14-28-10-5-9-20(22(28)32)27-35(33,34)16-17-6-2-1-3-7-17/h1-3,6-7,15,18-20,27H,4-5,8-14,16H2,(H3,24,25)(H,26,31) DATYERRDSFNBDN-UHFFFAOYSA-N 50054485 N-[(S)-1-((R)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide::CHEMBL342604 Coagulation factor X Homo sapiens >25000 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054485 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054485&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 10006399 103951093 CHEMBL342604 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50090529 [H]/N=C(\N)/N1CCC[C@H](C1)C[C@@H](C=O)NC(=O)CN2CCC[C@@H](C2=O)NS(=O)(=O)Cc3ccccc3 InChI=1S/C23H34N6O5S/c24-23(25)29-11-4-8-18(13-29)12-19(15-30)26-21(31)14-28-10-5-9-20(22(28)32)27-35(33,34)16-17-6-2-1-3-7-17/h1-3,6-7,15,18-20,27H,4-5,8-14,16H2,(H3,24,25)(H,26,31) DATYERRDSFNBDN-UHFFFAOYSA-N 50054486 N-[(S)-1-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide::CHEMBL141424 Anionic trypsin Bos taurus 64800.0 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054486 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000613&target=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054486&enzyme=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search 0KV 10074927 103951094 CHEMBL141424 1 MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS Anionic trypsin TRY2_BOVIN Q29463 50090530 NC(=N)NCCC[C@H](NC(=O)CN1CCC[C@H](NS(=O)(=O)Cc2ccccc2)C1=O)C=O InChI=1S/C20H30N6O5S/c21-20(22)23-10-4-8-16(13-27)24-18(28)12-26-11-5-9-17(19(26)29)25-32(30,31)14-15-6-2-1-3-7-15/h1-3,6-7,13,16-17,25H,4-5,8-12,14H2,(H,24,28)(H4,21,22,23) WZYFZDIYCCGIQM-UHFFFAOYSA-N 50054488 N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide::CVS-1178::CHEMBL138441 Anionic trypsin Bos taurus 1550 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054488 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000613&target=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054488&enzyme=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search 9847373 103951096 CHEMBL138441 1 MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS Anionic trypsin TRY2_BOVIN Q29463 50090531 NC(=N)N1CCCC(C[C@H](NC(=O)CN2CCCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C=O)C1 InChI=1S/C24H36N6O5S/c25-24(26)30-12-6-9-19(14-30)13-20(16-31)27-22(32)15-29-11-5-4-10-21(23(29)33)28-36(34,35)17-18-7-2-1-3-8-18/h1-3,7-8,16,19-21,28H,4-6,9-15,17H2,(H3,25,26)(H,27,32) JTGAZLYCGWWGII-UHFFFAOYSA-N 50054487 N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-azepan-1-yl)-acetamide::CHEMBL342914 Coagulation factor X Homo sapiens >2500 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054487 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054487&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 15431805 103951095 CHEMBL342914 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50090532 NC(=N)N1CCCC(C[C@H](NC(=O)CN2CCCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C=O)C1 InChI=1S/C24H36N6O5S/c25-24(26)30-12-6-9-19(14-30)13-20(16-31)27-22(32)15-29-11-5-4-10-21(23(29)33)28-36(34,35)17-18-7-2-1-3-8-18/h1-3,7-8,16,19-21,28H,4-6,9-15,17H2,(H3,25,26)(H,27,32) JTGAZLYCGWWGII-UHFFFAOYSA-N 50054487 N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-azepan-1-yl)-acetamide::CHEMBL342914 Prothrombin Homo sapiens 1.8 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054487 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054487&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search 15431805 103951095 CHEMBL342914 1 MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU Prothrombin THRB_HUMAN P00734 B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1 50090533 CCCC(CCC)C(=O)N[C@@H](CC(=O)OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C=O InChI=1S/C24H42N6O6/c1-4-8-16(9-5-2)21(33)29-18(14-20(32)36-3)23(35)30-13-7-11-19(30)22(34)28-17(15-31)10-6-12-27-24(25)26/h15-19H,4-14H2,1-3H3,(H,28,34)(H,29,33)(H4,25,26,27) ICMSWQUELAGTTR-UHFFFAOYSA-N 50054482 (S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-4-oxo-3-(2-propyl-pentanoylamino)-butyric acid methyl ester::CHEMBL141676 Prothrombin Homo sapiens 1.2 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054482 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054482&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search 9806376 103951090 CHEMBL141676 1 MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU Prothrombin THRB_HUMAN P00734 B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1 50090534 CCCC(CCC)C(=O)N[C@@H](CC(=O)OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1CCCN(C1)C(N)=N)C=O InChI=1S/C27H46N6O6/c1-4-8-19(9-5-2)24(36)31-21(15-23(35)39-3)26(38)33-13-7-11-22(33)25(37)30-20(17-34)14-18-10-6-12-32(16-18)27(28)29/h17-22H,4-16H2,1-3H3,(H3,28,29)(H,30,37)(H,31,36) HLEXEFPWIXSUIV-UHFFFAOYSA-N 50054483 (S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethylcarbamoyl]-pyrrolidin-1-yl}-4-oxo-3-(2-propyl-pentanoylamino)-butyric acid methyl ester::CHEMBL342838 Prothrombin Homo sapiens 1.7 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054483 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054483&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search 10325271 103951091 CHEMBL342838 1 MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU Prothrombin THRB_HUMAN P00734 B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1 50090535 [H]/N=C(\N)/N1CCC[C@H](C1)C[C@@H](C=O)NC(=O)CN2CCC[C@@H](C2=O)NS(=O)(=O)Cc3ccccc3 InChI=1S/C23H34N6O5S/c24-23(25)29-11-4-8-18(13-29)12-19(15-30)26-21(31)14-28-10-5-9-20(22(28)32)27-35(33,34)16-17-6-2-1-3-7-17/h1-3,6-7,15,18-20,27H,4-5,8-14,16H2,(H3,24,25)(H,26,31) DATYERRDSFNBDN-UHFFFAOYSA-N 50054486 N-[(S)-1-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide::CHEMBL141424 Coagulation factor X Homo sapiens >25000 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054486 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054486&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 0KV 1CA8,1YYY 10074927 103951094 CHEMBL141424 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50090536 CCCC(CCC)C(=O)N[C@@H](CC(=O)OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1CCCN(C1)C(N)=N)C=O InChI=1S/C27H46N6O6/c1-4-8-19(9-5-2)24(36)31-21(15-23(35)39-3)26(38)33-13-7-11-22(33)25(37)30-20(17-34)14-18-10-6-12-32(16-18)27(28)29/h17-22H,4-16H2,1-3H3,(H3,28,29)(H,30,37)(H,31,36) HLEXEFPWIXSUIV-UHFFFAOYSA-N 50054483 (S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethylcarbamoyl]-pyrrolidin-1-yl}-4-oxo-3-(2-propyl-pentanoylamino)-butyric acid methyl ester::CHEMBL342838 Prothrombin Homo sapiens 1.70 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054483 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054483&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search 10325271 103951091 CHEMBL342838 1 MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU Prothrombin THRB_HUMAN P00734 B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1 50090537 [H]/N=C(\N)/N1CCC[C@H](C1)C[C@@H](C=O)NC(=O)CN2CCC[C@@H](C2=O)NS(=O)(=O)Cc3ccccc3 InChI=1S/C23H34N6O5S/c24-23(25)29-11-4-8-18(13-29)12-19(15-30)26-21(31)14-28-10-5-9-20(22(28)32)27-35(33,34)16-17-6-2-1-3-7-17/h1-3,6-7,15,18-20,27H,4-5,8-14,16H2,(H3,24,25)(H,26,31) DATYERRDSFNBDN-UHFFFAOYSA-N 50054486 N-[(S)-1-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide::CHEMBL141424 Prothrombin Homo sapiens 0.67 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054486 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054486&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search 0KV 1CA8,1YYY 10074927 103951094 CHEMBL141424 1 MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU Prothrombin THRB_HUMAN P00734 B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1 50090538 NC(=N)N1CCC[C@H](C[C@H](NC(=O)CN2CCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C=O)C1 InChI=1S/C23H34N6O5S/c24-23(25)29-11-4-8-18(13-29)12-19(15-30)26-21(31)14-28-10-5-9-20(22(28)32)27-35(33,34)16-17-6-2-1-3-7-17/h1-3,6-7,15,18-20,27H,4-5,8-14,16H2,(H3,24,25)(H,26,31) DATYERRDSFNBDN-UHFFFAOYSA-N 50054485 N-[(S)-1-((R)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide::CHEMBL342604 Anionic trypsin Bos taurus 60700 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054485 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000613&target=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054485&enzyme=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search 10006399 103951093 CHEMBL342604 1 MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS Anionic trypsin TRY2_BOVIN Q29463 50090539 CCCC(CCC)C(=O)N[C@@H](CC(=O)OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C=O InChI=1S/C24H42N6O6/c1-4-8-16(9-5-2)21(33)29-18(14-20(32)36-3)23(35)30-13-7-11-19(30)22(34)28-17(15-31)10-6-12-27-24(25)26/h15-19H,4-14H2,1-3H3,(H,28,34)(H,29,33)(H4,25,26,27) ICMSWQUELAGTTR-UHFFFAOYSA-N 50054482 (S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-4-oxo-3-(2-propyl-pentanoylamino)-butyric acid methyl ester::CHEMBL141676 Anionic trypsin Bos taurus 1.2 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054482 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000613&target=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054482&enzyme=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search 9806376 103951090 CHEMBL141676 1 MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS Anionic trypsin TRY2_BOVIN Q29463 50090540 NC(=N)NCCC[C@H](NC(=O)CN1CCC[C@H](NS(=O)(=O)Cc2ccccc2)C1=O)C=O InChI=1S/C20H30N6O5S/c21-20(22)23-10-4-8-16(13-27)24-18(28)12-26-11-5-9-17(19(26)29)25-32(30,31)14-15-6-2-1-3-7-15/h1-3,6-7,13,16-17,25H,4-5,8-12,14H2,(H,24,28)(H4,21,22,23) WZYFZDIYCCGIQM-UHFFFAOYSA-N 50054488 N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide::CVS-1178::CHEMBL138441 Coagulation factor X Homo sapiens >2500 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054488 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054488&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 9847373 103951096 CHEMBL138441 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50090541 NC(=N)NCCC[C@H](NC(=O)CN1CCC[C@H](NS(=O)(=O)Cc2ccccc2)C1=O)C=O InChI=1S/C20H30N6O5S/c21-20(22)23-10-4-8-16(13-27)24-18(28)12-26-11-5-9-17(19(26)29)25-32(30,31)14-15-6-2-1-3-7-15/h1-3,6-7,13,16-17,25H,4-5,8-12,14H2,(H,24,28)(H4,21,22,23) WZYFZDIYCCGIQM-UHFFFAOYSA-N 50054488 N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide::CVS-1178::CHEMBL138441 Prothrombin Homo sapiens 12.4 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054488 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054488&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search 9847373 103951096 CHEMBL138441 1 MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU Prothrombin THRB_HUMAN P00734 B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1 50090542 NC(=N)N1CCCC(C[C@H](NC(=O)CN2CCCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C=O)C1 InChI=1S/C24H36N6O5S/c25-24(26)30-12-6-9-19(14-30)13-20(16-31)27-22(32)15-29-11-5-4-10-21(23(29)33)28-36(34,35)17-18-7-2-1-3-8-18/h1-3,7-8,16,19-21,28H,4-6,9-15,17H2,(H3,25,26)(H,27,32) JTGAZLYCGWWGII-UHFFFAOYSA-N 50054487 N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-azepan-1-yl)-acetamide::CHEMBL342914 Coagulation factor X Homo sapiens >2500 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054487 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054487&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 15431805 103951095 CHEMBL342914 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50090543 CCCC(CCC)C(=O)N[C@@H](CC(=O)OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1CCCN(C1)C(N)=N)C=O InChI=1S/C27H46N6O6/c1-4-8-19(9-5-2)24(36)31-21(15-23(35)39-3)26(38)33-13-7-11-22(33)25(37)30-20(17-34)14-18-10-6-12-32(16-18)27(28)29/h17-22H,4-16H2,1-3H3,(H3,28,29)(H,30,37)(H,31,36) HLEXEFPWIXSUIV-UHFFFAOYSA-N 50054483 (S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethylcarbamoyl]-pyrrolidin-1-yl}-4-oxo-3-(2-propyl-pentanoylamino)-butyric acid methyl ester::CHEMBL342838 Anionic trypsin Bos taurus 113 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054483 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000613&target=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054483&enzyme=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search 10325271 103951091 CHEMBL342838 1 MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS Anionic trypsin TRY2_BOVIN Q29463 50090544 NC(=N)NCCC[C@H](NC(=O)CN1CCCC[C@H](NS(=O)(=O)Cc2ccccc2)C1=O)C=O InChI=1S/C21H32N6O5S/c22-21(23)24-11-6-9-17(14-28)25-19(29)13-27-12-5-4-10-18(20(27)30)26-33(31,32)15-16-7-2-1-3-8-16/h1-3,7-8,14,17-18,26H,4-6,9-13,15H2,(H,25,29)(H4,22,23,24) PTYYNQHOHSWREY-UHFFFAOYSA-N 50054484 CVS-1778::N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-azepan-1-yl)-acetamide::CHEMBL344204 Prothrombin Homo sapiens 0.71 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054484 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054484&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search 9891337 103951092 CHEMBL344204 1 MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU Prothrombin THRB_HUMAN P00734 B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1 50090545 NC(=N)N1CCCC(C[C@H](NC(=O)CN2CCCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C=O)C1 InChI=1S/C24H36N6O5S/c25-24(26)30-12-6-9-19(14-30)13-20(16-31)27-22(32)15-29-11-5-4-10-21(23(29)33)28-36(34,35)17-18-7-2-1-3-8-18/h1-3,7-8,16,19-21,28H,4-6,9-15,17H2,(H3,25,26)(H,27,32) JTGAZLYCGWWGII-UHFFFAOYSA-N 50054487 N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-azepan-1-yl)-acetamide::CHEMBL342914 Anionic trypsin Bos taurus 15100 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054487 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000613&target=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054487&enzyme=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search 15431805 103951095 CHEMBL342914 1 MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS Anionic trypsin TRY2_BOVIN Q29463 50090546 CCCC(CCC)C(=O)N[C@@H](CC(=O)OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1CCCN(C1)C(N)=N)C=O InChI=1S/C27H46N6O6/c1-4-8-19(9-5-2)24(36)31-21(15-23(35)39-3)26(38)33-13-7-11-22(33)25(37)30-20(17-34)14-18-10-6-12-32(16-18)27(28)29/h17-22H,4-16H2,1-3H3,(H3,28,29)(H,30,37)(H,31,36) HLEXEFPWIXSUIV-UHFFFAOYSA-N 50054483 (S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethylcarbamoyl]-pyrrolidin-1-yl}-4-oxo-3-(2-propyl-pentanoylamino)-butyric acid methyl ester::CHEMBL342838 Anionic trypsin Bos taurus 113 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054483 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000613&target=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054483&enzyme=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search 10325271 103951091 CHEMBL342838 1 MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS Anionic trypsin TRY2_BOVIN Q29463 50090547 NC(=N)NCCC[C@H](NC(=O)CN1CCCC[C@H](NS(=O)(=O)Cc2ccccc2)C1=O)C=O InChI=1S/C21H32N6O5S/c22-21(23)24-11-6-9-17(14-28)25-19(29)13-27-12-5-4-10-18(20(27)30)26-33(31,32)15-16-7-2-1-3-8-16/h1-3,7-8,14,17-18,26H,4-6,9-13,15H2,(H,25,29)(H4,22,23,24) PTYYNQHOHSWREY-UHFFFAOYSA-N 50054484 CVS-1778::N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-azepan-1-yl)-acetamide::CHEMBL344204 Anionic trypsin Bos taurus 329 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054484 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000613&target=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054484&enzyme=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search 9891337 103951092 CHEMBL344204 1 MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS Anionic trypsin TRY2_BOVIN Q29463 50090548 NC(=N)N1CCCC(C[C@H](NC(=O)CN2CCCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C=O)C1 InChI=1S/C24H36N6O5S/c25-24(26)30-12-6-9-19(14-30)13-20(16-31)27-22(32)15-29-11-5-4-10-21(23(29)33)28-36(34,35)17-18-7-2-1-3-8-18/h1-3,7-8,16,19-21,28H,4-6,9-15,17H2,(H3,25,26)(H,27,32) JTGAZLYCGWWGII-UHFFFAOYSA-N 50054487 N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-azepan-1-yl)-acetamide::CHEMBL342914 Anionic trypsin Bos taurus 15100 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054487 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000613&target=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054487&enzyme=Anionic+trypsin&column=ki&startPg=0&Increment=50&submit=Search 15431805 103951095 CHEMBL342914 1 MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS Anionic trypsin TRY2_BOVIN Q29463 50090549 NC(=N)N1CCCC(C[C@H](NC(=O)CN2CCCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C=O)C1 InChI=1S/C24H36N6O5S/c25-24(26)30-12-6-9-19(14-30)13-20(16-31)27-22(32)15-29-11-5-4-10-21(23(29)33)28-36(34,35)17-18-7-2-1-3-8-18/h1-3,7-8,16,19-21,28H,4-6,9-15,17H2,(H3,25,26)(H,27,32) JTGAZLYCGWWGII-UHFFFAOYSA-N 50054487 N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-azepan-1-yl)-acetamide::CHEMBL342914 Prothrombin Homo sapiens 1.80 ChEMBL 10.1021/jm960607j 10.7270/Q2CR5SFV 8917638 Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF 12/26/1996 11/10/2009 Corvas International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054487 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054487&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search 15431805 103951095 CHEMBL342914 1 MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU Prothrombin THRB_HUMAN P00734 B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1