BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50793160 CCN(c1nc(C)cc(C)n1)c1ccc(cc1Br)C(C)C InChI=1S/C17H22BrN3/c1-6-21(17-19-12(4)9-13(5)20-17)16-8-7-14(11(2)3)10-15(16)18/h7-11H,6H2,1-5H3 YUEVFPATPSQDPG-UHFFFAOYSA-N 50074350 (2-Bromo-4-isopropyl-phenyl)-(4,6-dimethyl-pyrimidin-2-yl)-ethyl-amine::CHEMBL167264 Corticotropin-releasing factor receptor 1 Rattus norvegicus 46 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074350 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074350&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10831554 103967567 CHEMBL167264 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793161 CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(C)cc(nc12)-c1ccccc1 InChI=1S/C24H20BrN3/c1-15(2)18-9-10-22(20(25)12-18)28-14-19(13-26)23-16(3)11-21(27-24(23)28)17-7-5-4-6-8-17/h4-12,14-15H,1-3H3 KNZLMAKWLCBTLO-UHFFFAOYSA-N 50074415 1-(2-Bromo-4-isopropyl-phenyl)-4-methyl-6-phenyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile::CHEMBL169507 Corticotropin-releasing factor receptor 1 Rattus norvegicus >100000 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074415 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074415&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10741267 103967632 CHEMBL169507 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793162 CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(C)cc(=O)[nH]c12 InChI=1S/C18H16BrN3O/c1-10(2)12-4-5-15(14(19)7-12)22-9-13(8-20)17-11(3)6-16(23)21-18(17)22/h4-7,9-10H,1-3H3,(H,21,23) DZHYYJXOBIBELN-UHFFFAOYSA-N 50074416 1-(2-Bromo-4-isopropyl-phenyl)-6-hydroxy-4-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile::CHEMBL355135 Corticotropin-releasing factor receptor 1 Rattus norvegicus >10000 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074416 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074416&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10809156 103967633 CHEMBL355135 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793163 CCN(c1nc(C)cc(n1)N1CCOCC1)c1ccc(cc1Br)C(C)C InChI=1S/C20H27BrN4O/c1-5-25(18-7-6-16(14(2)3)13-17(18)21)20-22-15(4)12-19(23-20)24-8-10-26-11-9-24/h6-7,12-14H,5,8-11H2,1-4H3 DQSVEQFHEZHQRX-UHFFFAOYSA-N 50074372 (2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-morpholin-4-yl-pyrimidin-2-yl)-amine::CHEMBL432496 Corticotropin-releasing factor receptor 1 Rattus norvegicus 22 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074372 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074372&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10549990 103967589 CHEMBL432496 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793164 CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(C)cc(Cl)nc12 InChI=1S/C18H15BrClN3/c1-10(2)12-4-5-15(14(19)7-12)23-9-13(8-21)17-11(3)6-16(20)22-18(17)23/h4-7,9-10H,1-3H3 QHJTVYSIDYDLIS-UHFFFAOYSA-N 50074417 1-(2-Bromo-4-isopropyl-phenyl)-6-chloro-4-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile::CHEMBL166946 Corticotropin-releasing factor receptor 1 Rattus norvegicus 446 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074417 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074417&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10739049 103967634 CHEMBL166946 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793165 CC(C)c1ccc(N(C)c2nc(C)cc(C)n2)c(Br)c1 InChI=1S/C16H20BrN3/c1-10(2)13-6-7-15(14(17)9-13)20(5)16-18-11(3)8-12(4)19-16/h6-10H,1-5H3 NZHPYWKTCLZWBM-UHFFFAOYSA-N 50074408 (2-Bromo-4-isopropyl-phenyl)-(4,6-dimethyl-pyrimidin-2-yl)-methyl-amine::CHEMBL168568 Corticotropin-releasing factor receptor 1 Rattus norvegicus 96 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074408 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074408&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10616689 103967625 CHEMBL168568 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793166 CCN(c1cc(C)nc(C)n1)c1ccc(cc1Br)C(C)C InChI=1S/C17H22BrN3/c1-6-21(17-9-12(4)19-13(5)20-17)16-8-7-14(11(2)3)10-15(16)18/h7-11H,6H2,1-5H3 AHZVBDFXNOHIAP-UHFFFAOYSA-N 50074418 (2-Bromo-4-isopropyl-phenyl)-(2,6-dimethyl-pyrimidin-4-yl)-ethyl-amine::CHEMBL355289 Corticotropin-releasing factor receptor 1 Rattus norvegicus >1000 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074418 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074418&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44380096 103967635 CHEMBL355289 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793167 CC(C)c1ccc(c(Br)c1)-n1ccc2c(C)cc(Cl)nc12 InChI=1S/C17H16BrClN2/c1-10(2)12-4-5-15(14(18)9-12)21-7-6-13-11(3)8-16(19)20-17(13)21/h4-10H,1-3H3 PNGHDPQUCWMVKJ-UHFFFAOYSA-N 50074419 1-(2-Bromo-4-isopropyl-phenyl)-6-chloro-4-methyl-1H-pyrrolo[2,3-b]pyridine::CHEMBL355882 Corticotropin-releasing factor receptor 1 Rattus norvegicus 79 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074419 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074419&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10666432 103967636 CHEMBL355882 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793168 COc1cc(Br)c(c(OC)c1)-n1cc(C#N)c2c(C)cc(C)nc12 |(12.47,-15.06,;10.97,-14.75,;10.48,-13.3,;11.5,-12.14,;11.01,-10.69,;12.02,-9.53,;9.5,-10.37,;8.48,-11.53,;6.98,-11.21,;5.96,-12.35,;8.97,-12.98,;9.03,-8.92,;9.92,-7.66,;9.01,-6.42,;9.48,-4.95,;9.95,-3.48,;7.54,-6.91,;6.21,-6.14,;6.21,-4.6,;4.88,-6.91,;4.88,-8.45,;3.55,-9.22,;6.21,-9.22,;7.56,-8.45,)| InChI=1S/C18H16BrN3O2/c1-10-5-11(2)21-18-16(10)12(8-20)9-22(18)17-14(19)6-13(23-3)7-15(17)24-4/h5-7,9H,1-4H3 ZMXAHDWFFGRSOY-UHFFFAOYSA-N 50074420 1-(2-Bromo-4,6-dimethoxy-phenyl)-4,6-dimethyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile::CHEMBL169838 Corticotropin-releasing factor receptor 1 Rattus norvegicus 29 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074420 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074420&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10548172 103967637 CHEMBL169838 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793169 CC(C)c1ccc(c(Br)c1)-n1ccc2c(C)cc(nc12)-c1ccccc1 InChI=1S/C23H21BrN2/c1-15(2)18-9-10-22(20(24)14-18)26-12-11-19-16(3)13-21(25-23(19)26)17-7-5-4-6-8-17/h4-15H,1-3H3 LUFGBBKPEKJDQF-UHFFFAOYSA-N 50074422 1-(2-Bromo-4-isopropyl-phenyl)-4-methyl-6-phenyl-1H-pyrrolo[2,3-b]pyridine::CHEMBL169004 Corticotropin-releasing factor receptor 1 Rattus norvegicus >100000 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074422 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074422&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10644965 103967639 CHEMBL169004 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793170 CC(C)c1ccc(c(Br)c1)-n1cc(C(O)=O)c2c(C)cc(C)nc12 InChI=1S/C19H19BrN2O2/c1-10(2)13-5-6-16(15(20)8-13)22-9-14(19(23)24)17-11(3)7-12(4)21-18(17)22/h5-10H,1-4H3,(H,23,24) XMTQGGDMLQSVQZ-UHFFFAOYSA-N 50074421 1-(2-Bromo-4-isopropyl-phenyl)-4,6-dimethyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid::CHEMBL170055 Corticotropin-releasing factor receptor 1 Rattus norvegicus >10000 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074421 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074421&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10715231 103967638 CHEMBL170055 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793171 CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(cc(C)nc12)N1CCOCC1 InChI=1S/C22H23BrN4O/c1-14(2)16-4-5-19(18(23)11-16)27-13-17(12-24)21-20(10-15(3)25-22(21)27)26-6-8-28-9-7-26/h4-5,10-11,13-14H,6-9H2,1-3H3 KACNKJYBUQBAPA-UHFFFAOYSA-N 50074423 1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-4-morpholin-4-yl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile::CHEMBL166760 Corticotropin-releasing factor receptor 1 Rattus norvegicus 112 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074423 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074423&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10551027 103967640 CHEMBL166760 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793172 CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2ccc(C)nc12 InChI=1S/C18H16BrN3/c1-11(2)13-5-7-17(16(19)8-13)22-10-14(9-20)15-6-4-12(3)21-18(15)22/h4-8,10-11H,1-3H3 RIRFTBCYCYBZNQ-UHFFFAOYSA-N 50074424 1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile::CHEMBL354092 Corticotropin-releasing factor receptor 1 Rattus norvegicus 1277 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074424 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074424&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10641825 103967641 CHEMBL354092 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793173 CCN(c1nc(C)cc(C)n1)c1ccc(cc1I)C(C)C InChI=1S/C17H22IN3/c1-6-21(17-19-12(4)9-13(5)20-17)16-8-7-14(11(2)3)10-15(16)18/h7-11H,6H2,1-5H3 XQPGFRBWNCMCSY-UHFFFAOYSA-N 50074351 (4,6-Dimethyl-pyrimidin-2-yl)-ethyl-(2-iodo-4-isopropyl-phenyl)-amine::CHEMBL166162 Corticotropin-releasing factor receptor 1 Rattus norvegicus 38 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074351 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074351&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10786842 103967568 CHEMBL166162 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793174 CC(C)c1ccc(c(Br)c1)-n1ccc2c(C)ccnc12 InChI=1S/C17H17BrN2/c1-11(2)13-4-5-16(15(18)10-13)20-9-7-14-12(3)6-8-19-17(14)20/h4-11H,1-3H3 VUZACCWXHJGWCM-UHFFFAOYSA-N 50074426 1-(2-Bromo-4-isopropyl-phenyl)-4-methyl-1H-pyrrolo[2,3-b]pyridine::CHEMBL168784 Corticotropin-releasing factor receptor 1 Rattus norvegicus >10000 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074426 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074426&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10758707 103967643 CHEMBL168784 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793175 CC(C)c1ccc(c(Br)c1)-n1ccc2c(Cl)cc(C)nc12 InChI=1S/C17H16BrClN2/c1-10(2)12-4-5-16(14(18)9-12)21-7-6-13-15(19)8-11(3)20-17(13)21/h4-10H,1-3H3 PUXGFALKNTZHGS-UHFFFAOYSA-N 50074430 1-(2-Bromo-4-isopropyl-phenyl)-4-chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine::CHEMBL353774 Corticotropin-releasing factor receptor 1 Rattus norvegicus 67 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074430 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074430&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10832559 103967647 CHEMBL353774 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793176 CCN(c1nc(C)cc(C)n1)c1c(Br)cc(OC)cc1OC InChI=1S/C16H20BrN3O2/c1-6-20(16-18-10(2)7-11(3)19-16)15-13(17)8-12(21-4)9-14(15)22-5/h7-9H,6H2,1-5H3 OQFBRKSYUGLJSA-UHFFFAOYSA-N 50074411 (2-Bromo-4,6-dimethoxy-phenyl)-(4,6-dimethyl-pyrimidin-2-yl)-ethyl-amine::CHEMBL46479 Corticotropin-releasing factor receptor 1 Rattus norvegicus 5 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074411 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074411&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9907170 103967628 CHEMBL46479 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793177 CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(cc(C)nc12)-c1ccccc1 InChI=1S/C24H20BrN3/c1-15(2)18-9-10-22(21(25)12-18)28-14-19(13-26)23-20(11-16(3)27-24(23)28)17-7-5-4-6-8-17/h4-12,14-15H,1-3H3 IZPTWDGBBSSUFN-UHFFFAOYSA-N 50074425 1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-4-phenyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile::CHEMBL353916 Corticotropin-releasing factor receptor 1 Rattus norvegicus 34 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074425 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074425&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10502734 103967642 CHEMBL353916 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793178 CC(C)c1ccc(c(Br)c1)-n1ccc2c(cc(C)nc12)-c1ccccc1 InChI=1S/C23H21BrN2/c1-15(2)18-9-10-22(21(24)14-18)26-12-11-19-20(13-16(3)25-23(19)26)17-7-5-4-6-8-17/h4-15H,1-3H3 NIQBQCGMLBLOAL-UHFFFAOYSA-N 50074429 1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-4-phenyl-1H-pyrrolo[2,3-b]pyridine::CHEMBL169359 Corticotropin-releasing factor receptor 1 Rattus norvegicus 36 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074429 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074429&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10787443 103967646 CHEMBL169359 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793179 CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(C)cc(C)nc12 InChI=1S/C19H18BrN3/c1-11(2)14-5-6-17(16(20)8-14)23-10-15(9-21)18-12(3)7-13(4)22-19(18)23/h5-8,10-11H,1-4H3 PIGVJMHCKKTORD-UHFFFAOYSA-N 50074427 1-(2-Bromo-4-isopropyl-phenyl)-4,6-dimethyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile::CHEMBL168590 Corticotropin-releasing factor receptor 1 Rattus norvegicus 363 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074427 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074427&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10737736 103967644 CHEMBL168590 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793180 CC(C)c1ccc(c(Br)c1)-n1ccc2c(cc(C)nc12)N1CCOCC1 InChI=1S/C21H24BrN3O/c1-14(2)16-4-5-19(18(22)13-16)25-7-6-17-20(12-15(3)23-21(17)25)24-8-10-26-11-9-24/h4-7,12-14H,8-11H2,1-3H3 QCBKMFQKFWBGMQ-UHFFFAOYSA-N 50074435 1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-4-morpholin-4-yl-1H-pyrrolo[2,3-b]pyridine::CHEMBL46798 Corticotropin-releasing factor receptor 1 Rattus norvegicus 28 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074435 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074435&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10740490 103967652 CHEMBL46798 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793181 CC(C)c1ccc(c(Br)c1)-n1ccc2c(C)cc(C)nc12 InChI=1S/C18H19BrN2/c1-11(2)14-5-6-17(16(19)10-14)21-8-7-15-12(3)9-13(4)20-18(15)21/h5-11H,1-4H3 QFPQNRRUWQDVHQ-UHFFFAOYSA-N 50074437 1-(2-Bromo-4-isopropyl-phenyl)-4,6-dimethyl-1H-pyrrolo[2,3-b]pyridine::CHEMBL169784 Corticotropin-releasing factor receptor 1 Rattus norvegicus 47 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074437 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074437&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10497535 103967654 CHEMBL169784 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793182 CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2ccc(C)[n+]([O-])c12 InChI=1S/C18H16BrN3O/c1-11(2)13-5-7-17(16(19)8-13)21-10-14(9-20)15-6-4-12(3)22(23)18(15)21/h4-8,10-11H,1-3H3 ZAJNIGMCANZTLM-UHFFFAOYSA-N 50074431 1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-7-oxy-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile::CHEMBL166945 Corticotropin-releasing factor receptor 1 Rattus norvegicus >10000 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074431 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074431&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10595309 103967648 CHEMBL166945 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793183 CC(C)c1ccc(N(C)c2nc(C)cc(C)n2)c(I)c1 InChI=1S/C16H20IN3/c1-10(2)13-6-7-15(14(17)9-13)20(5)16-18-11(3)8-12(4)19-16/h6-10H,1-5H3 ZHKMPZIOTNOMOD-UHFFFAOYSA-N 50074432 (4,6-Dimethyl-pyrimidin-2-yl)-(2-iodo-4-isopropyl-phenyl)-methyl-amine::CHEMBL355624 Corticotropin-releasing factor receptor 1 Rattus norvegicus 48 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074432 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074432&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44380639 103967649 CHEMBL355624 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793184 CC(C)c1ccc(cc1)-n1ccc2c(C)cc(C)nc12 InChI=1S/C18H20N2/c1-12(2)15-5-7-16(8-6-15)20-10-9-17-13(3)11-14(4)19-18(17)20/h5-12H,1-4H3 PCFKEZPOCNMGNB-UHFFFAOYSA-N 50074433 1-(4-Isopropyl-phenyl)-4,6-dimethyl-1H-pyrrolo[2,3-b]pyridine::CHEMBL415752 Corticotropin-releasing factor receptor 1 Rattus norvegicus 2462 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074433 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074433&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10801589 103967650 CHEMBL415752 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793185 CCN(c1nc(C)nc(n1)N1CCOCC1)c1c(Br)cc(OC)cc1OC InChI=1S/C18H24BrN5O3/c1-5-24(16-14(19)10-13(25-3)11-15(16)26-4)18-21-12(2)20-17(22-18)23-6-8-27-9-7-23/h10-11H,5-9H2,1-4H3 FKWFEXHQWCTXFD-UHFFFAOYSA-N 50074353 CHEMBL424204::CHEMBL43216::(2-Bromo-4,6-dimethoxy-phenyl)-ethyl-(4-methyl-6-morpholin-4-yl-[1,3,5]triazin-2-yl)-amine Corticotropin-releasing factor receptor 1 Rattus norvegicus 43 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074353 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074353&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9828535 103967570 CHEMBL43216CHEMBL424204 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793186 CC(C)c1ccc(Nc2nc(C)cc(C)n2)c(Br)c1 InChI=1S/C15H18BrN3/c1-9(2)12-5-6-14(13(16)8-12)19-15-17-10(3)7-11(4)18-15/h5-9H,1-4H3,(H,17,18,19) YQAFFHYPUXODMI-UHFFFAOYSA-N 50074436 (2-Bromo-4-isopropyl-phenyl)-(4,6-dimethyl-pyrimidin-2-yl)-amine::CHEMBL355218 Corticotropin-releasing factor receptor 1 Rattus norvegicus >10000 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074436 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074436&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10591763 103967653 CHEMBL355218 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793187 CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(C)ccnc12 InChI=1S/C18H16BrN3/c1-11(2)13-4-5-16(15(19)8-13)22-10-14(9-20)17-12(3)6-7-21-18(17)22/h4-8,10-11H,1-3H3 BRMLMCCMPKITGY-UHFFFAOYSA-N 50074438 1-(2-Bromo-4-isopropyl-phenyl)-4-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile::CHEMBL165818 Corticotropin-releasing factor receptor 1 Rattus norvegicus >10000 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074438 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074438&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10808015 103967655 CHEMBL165818 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793188 COc1cc(Br)c(c(OC)c1)-n1ccc2c(C)cc(C)nc12 |(12.47,-15.06,;10.97,-14.75,;10.48,-13.3,;11.5,-12.14,;11.01,-10.69,;12.02,-9.53,;9.5,-10.37,;8.48,-11.53,;6.98,-11.21,;5.96,-12.35,;8.97,-12.98,;9.03,-8.92,;9.92,-7.66,;9.01,-6.42,;7.54,-6.91,;6.21,-6.14,;6.21,-4.6,;4.88,-6.91,;4.88,-8.45,;3.55,-9.22,;6.21,-9.22,;7.56,-8.45,)| InChI=1S/C17H17BrN2O2/c1-10-7-11(2)19-17-13(10)5-6-20(17)16-14(18)8-12(21-3)9-15(16)22-4/h5-9H,1-4H3 KPARZMBGRLAYAL-UHFFFAOYSA-N 50074439 1-(2-Bromo-4,6-dimethoxy-phenyl)-4,6-dimethyl-1H-pyrrolo[2,3-b]pyridine::CHEMBL167241 Corticotropin-releasing factor receptor 1 Rattus norvegicus 1 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074439 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074439&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9998661 103967656 CHEMBL167241 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793189 CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(Cl)cc(C)nc12 InChI=1S/C18H15BrClN3/c1-10(2)12-4-5-16(14(19)7-12)23-9-13(8-21)17-15(20)6-11(3)22-18(17)23/h4-7,9-10H,1-3H3 PRRTYZKNYJKSNF-UHFFFAOYSA-N 50074440 1-(2-Bromo-4-isopropyl-phenyl)-4-chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile::CHEMBL166732 Corticotropin-releasing factor receptor 1 Rattus norvegicus 722 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074440 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074440&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10644018 103967657 CHEMBL166732 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793190 CC(C)c1ccc(c(Br)c1)-n1ccc2ccc(C)nc12 InChI=1S/C17H17BrN2/c1-11(2)14-6-7-16(15(18)10-14)20-9-8-13-5-4-12(3)19-17(13)20/h4-11H,1-3H3 GSZLRKKRTKNCQK-UHFFFAOYSA-N 50074442 1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-1H-pyrrolo[2,3-b]pyridine::CHEMBL170487 Corticotropin-releasing factor receptor 1 Rattus norvegicus 222 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074442 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074442&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10782556 103967659 CHEMBL170487 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353 50793191 CC(C)c1ccc(c(Br)c1)-n1cc(C(N)=O)c2c(C)cc(C)nc12 InChI=1S/C19H20BrN3O/c1-10(2)13-5-6-16(15(20)8-13)23-9-14(18(21)24)17-11(3)7-12(4)22-19(17)23/h5-10H,1-4H3,(H2,21,24) UBSCLSRXBDVDMI-UHFFFAOYSA-N 50074441 1-(2-Bromo-4-isopropyl-phenyl)-4,6-dimethyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid amide::CHEMBL355136 Corticotropin-releasing factor receptor 1 Rattus norvegicus >10000 ChEMBL 10.1021/jm980223o 10.7270/Q22V2GT5 10072680 Hodge, CN; Aldrich, PE; Wasserman, ZR; Fernandez, CH; Nemeth, GA; Arvanitis, A; Cheeseman, RS; Chorvat, RJ; Ciganek, E; Christos, TE; Gilligan, PJ; Krenitsky, P; Scholfield, E; Strucely, P 4/13/1999 11/13/2012 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074441 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3623&target=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074441&enzyme=Corticotropin-releasing+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10667845 103967658 CHEMBL355136 1 MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV Corticotropin-releasing factor receptor 1 CRFR1_RAT P35353