BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
50132298	NC(=N)NCCC[C@H](NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1)C(=O)c1nc2CCCc2s1	InChI=1S/C29H37N7O4S/c30-29(31)32-15-5-9-21(26(39)28-34-20-8-4-10-23(20)41-28)33-27(40)22-13-12-19-16-35(17-25(38)36(19)22)24(37)14-11-18-6-2-1-3-7-18/h1-3,6-7,19,21-22H,4-5,8-17H2,(H,33,40)(H4,30,31,32)	HGZAKQZABFGBLF-UHFFFAOYSA-N	50076012	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-1-(5,6-dihydro-4H-cyclopentathiazole-2-carbonyl)-4-guanidino-butyl]-amide::CHEMBL169291	Prothrombin	Homo sapiens		 18							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076012	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076012&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			44380722	103969010		CHEMBL169291					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132299	NC(=N)NCCC[C@H](NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1)C(=O)c1nccs1	InChI=1S/C26H33N7O4S/c27-26(28)30-12-4-7-19(23(36)25-29-13-14-38-25)31-24(37)20-10-9-18-15-32(16-22(35)33(18)20)21(34)11-8-17-5-2-1-3-6-17/h1-3,5-6,13-14,18-20H,4,7-12,15-16H2,(H,31,37)(H4,27,28,30)	LAGUWJUZJRIYRI-UHFFFAOYSA-N	50072740	(S)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [4-guanidino-1-((S)-thiazole-2-carbonyl)-butyl]-amide::(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-4-guanidino-1-(thiazole-2-carbonyl)-butyl]-amide::(6S,8aS)-N-((S)-5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-yl)-4-oxo-2-(3-phenylpropanoyl)-octahydropyrrolo[1,2-a]pyrazine-6-carboxamide::CHEMBL324413	Prothrombin	Homo sapiens		 5							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072740	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072740&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			9958913	103966342		CHEMBL324413					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132300	NC(=N)NCCC[C@H](NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1)C(=O)c1nc2CCCc2s1	InChI=1S/C29H37N7O4S/c30-29(31)32-15-5-9-21(26(39)28-34-20-8-4-10-23(20)41-28)33-27(40)22-13-12-19-16-35(17-25(38)36(19)22)24(37)14-11-18-6-2-1-3-7-18/h1-3,6-7,19,21-22H,4-5,8-17H2,(H,33,40)(H4,30,31,32)	HGZAKQZABFGBLF-UHFFFAOYSA-N	50076012	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-1-(5,6-dihydro-4H-cyclopentathiazole-2-carbonyl)-4-guanidino-butyl]-amide::CHEMBL169291	Serine protease 1	Homo sapiens		 2							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076012	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076012&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			44380722	103969010		CHEMBL169291					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132301	NC(=N)c1cccc(CC(NC(=O)[C@@H]2CC[C@H]3CN(CC(=O)N23)C(=O)CCc2ccccc2)C(=O)c2nc3ccccc3s2)c1	InChI=1S/C34H34N6O4S/c35-32(36)23-10-6-9-22(17-23)18-26(31(43)34-38-25-11-4-5-12-28(25)45-34)37-33(44)27-15-14-24-19-39(20-30(42)40(24)27)29(41)16-13-21-7-2-1-3-8-21/h1-12,17,24,26-27H,13-16,18-20H2,(H3,35,36)(H,37,44)	GOBFKUOZUDEDMD-UHFFFAOYSA-N	50076013	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [2-benzothiazol-2-yl-1-(3-carbamimidoyl-benzyl)-2-oxo-ethyl]-amide::CHEMBL166543	Prothrombin	Homo sapiens		 57							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076013	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076013&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			44381062	103969011		CHEMBL166543					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132302	Cc1csc(n1)C(=O)C(CCCNC(N)=N)NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1	InChI=1S/C27H35N7O4S/c1-17-16-39-26(31-17)24(37)20(8-5-13-30-27(28)29)32-25(38)21-11-10-19-14-33(15-23(36)34(19)21)22(35)12-9-18-6-3-2-4-7-18/h2-4,6-7,16,19-21H,5,8-15H2,1H3,(H,32,38)(H4,28,29,30)	ALLMDIRYOKTDHH-UHFFFAOYSA-N	50076015	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [4-guanidino-1-(4-methyl-thiazole-2-carbonyl)-butyl]-amide::CHEMBL169067	Serine protease 1	Homo sapiens		 24							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076015	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076015&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			44380662	103969013		CHEMBL169067					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132303	Cn1c(nc2ccccc12)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1	InChI=1S/C35H37N7O4/c1-40-28-13-6-5-12-26(28)38-34(40)32(45)27(19-23-10-7-11-24(18-23)33(36)37)39-35(46)29-16-15-25-20-41(21-31(44)42(25)29)30(43)17-14-22-8-3-2-4-9-22/h2-13,18,25,27,29H,14-17,19-21H2,1H3,(H3,36,37)(H,39,46)	AWCMDTMSPRXSSZ-UHFFFAOYSA-N	50076014	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-1-(3-carbamimidoyl-benzyl)-2-(1-methyl-1H-benzoimidazol-2-yl)-2-oxo-ethyl]-amide::CHEMBL168411	Serine protease 1	Homo sapiens		 18680							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076014&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			44381063	103969012		CHEMBL168411					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132304	NC(=N)N1CCCC(C[C@H](NC(=O)[C@@H]2CC[C@H]3CN(CC(=O)N23)C(=O)CCc2ccccc2)C(=O)c2nc3ccccc3s2)C1	InChI=1S/C33H39N7O4S/c34-33(35)38-16-6-9-22(18-38)17-25(30(43)32-37-24-10-4-5-11-27(24)45-32)36-31(44)26-14-13-23-19-39(20-29(42)40(23)26)28(41)15-12-21-7-2-1-3-8-21/h1-5,7-8,10-11,22-23,25-26H,6,9,12-20H2,(H3,34,35)(H,36,44)	XCVRAVMOZULGSZ-UHFFFAOYSA-N	50076017	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-2-benzothiazol-2-yl-1-(1-carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-amide::CHEMBL433911	Serine protease 1	Homo sapiens		 590							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076017	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076017&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			10009177	103969015		CHEMBL433911					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132305	Cn1c(nc2ccccc12)C(=O)[C@H](CC1CCCN(C1)C(N)=N)NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1	InChI=1S/C34H42N8O4/c1-39-27-12-6-5-11-25(27)37-32(39)31(45)26(18-23-10-7-17-40(19-23)34(35)36)38-33(46)28-15-14-24-20-41(21-30(44)42(24)28)29(43)16-13-22-8-3-2-4-9-22/h2-6,8-9,11-12,23-24,26,28H,7,10,13-21H2,1H3,(H3,35,36)(H,38,46)	AGXPUGADDPTAMM-UHFFFAOYSA-N	50076016	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-1-(1-carbamimidoyl-piperidin-3-ylmethyl)-2-(1-methyl-1H-benzoimidazol-2-yl)-2-oxo-ethyl]-amide::CHEMBL170490	Prothrombin	Homo sapiens		 750							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076016	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076016&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			44380741	103969014		CHEMBL170490					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132306	[#6]-n1c(nc2ccccc12)-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6@H]-2-[#6]-[#7](-[#6]-[#6](=O)-[#7]-1-2)-[#6](=O)-[#6]-[#6]-c1ccccc1	InChI=1S/C31H12N8O4/c1-37-24-12-6-5-10-22(24)35-29(37)28(42)23(11-7-17-34-31(32)33)36-30(43)25-15-14-21-18-38(19-27(41)39(21)25)26(40)16-13-20-8-3-2-4-9-20/h2-6,8-10,12,21,23,25H	AWTZHJRNZLSQHN-UHFFFAOYSA-N	50228718	(6S,8aS)-N-((S)-5-guanidino-1-(1-methyl-1H-benzo[d]imidazol-2-yl)-1-oxopentan-2-yl)-4-oxo-2-(3-phenylpropanoyl)-octahydropyrrolo[1,2-a]pyrazine-6-carboxamide::(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-4-guanidino-1-(1-methyl-1H-benzoimidazole-2-carbonyl)-butyl]-amide::CHEMBL256396	Prothrombin	Homo sapiens		 51							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50228718	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50228718&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			44453663	104097951		CHEMBL256396					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132309	NC(=N)NCCC[C@H](NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1)C(=O)c1ccccn1	InChI=1S/C28H35N7O4/c29-28(30)32-16-6-10-22(26(38)21-9-4-5-15-31-21)33-27(39)23-13-12-20-17-34(18-25(37)35(20)23)24(36)14-11-19-7-2-1-3-8-19/h1-5,7-9,15,20,22-23H,6,10-14,16-18H2,(H,33,39)(H4,29,30,32)	QXCKDSSZBUCQET-UHFFFAOYSA-N	50076020	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-4-guanidino-1-(pyridine-2-carbonyl)-butyl]-amide::(6S,8aS)-N-((S)-5-guanidino-1-oxo-1-(pyridin-2-yl)pentan-2-yl)-4-oxo-2-(3-phenylpropanoyl)-octahydropyrrolo[1,2-a]pyrazine-6-carboxamide::CHEMBL169946	Serine protease 1	Homo sapiens		 160							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076020	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076020&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			44380674	103969017		CHEMBL169946					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132311	Cn1c(nc2ccccc12)C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1	InChI=1S/C31H38N6O4/c1-35-25-13-6-5-11-23(25)33-30(35)29(40)24(12-7-8-18-32)34-31(41)26-16-15-22-19-36(20-28(39)37(22)26)27(38)17-14-21-9-3-2-4-10-21/h2-6,9-11,13,22,24,26H,7-8,12,14-20,32H2,1H3,(H,34,41)	XRXUBCLWSQSKHT-UHFFFAOYSA-N	50076019	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-5-amino-1-(1-methyl-1H-benzoimidazole-2-carbonyl)-pentyl]-amide::CHEMBL168280	Serine protease 1	Homo sapiens		 8490							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076019	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076019&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			44380740	103969016		CHEMBL168280					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132312	[#6]-n1ccnc1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6@H]-2-[#6]-[#7](-[#6]-[#6](=O)-[#7]-1-2)-[#6](=O)-[#6]-[#6]-c1ccccc1	InChI=1S/C27H10N8O4/c1-33-15-14-30-25(33)24(38)20(8-5-13-31-27(28)29)32-26(39)21-11-10-19-16-34(17-23(37)35(19)21)22(36)12-9-18-6-3-2-4-7-18/h2-4,6-7,14-15,19-21H	HUXGNFSKJFYXEL-UHFFFAOYSA-N	50228717	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-4-guanidino-1-(1-methyl-1H-imidazole-2-carbonyl)-butyl]-amide::(6S,8aS)-N-((S)-5-guanidino-1-(1-methyl-1H-imidazol-2-yl)-1-oxopentan-2-yl)-4-oxo-2-(3-phenylpropanoyl)-octahydropyrrolo[1,2-a]pyrazine-6-carboxamide::CHEMBL256030	Serine protease 1	Homo sapiens		 27400							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50228717	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50228717&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			44453904	104097950		CHEMBL256030					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132313	Cn1c(nc2ccccc12)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1	InChI=1S/C35H37N7O4/c1-40-28-13-6-5-12-26(28)38-34(40)32(45)27(19-23-10-7-11-24(18-23)33(36)37)39-35(46)29-16-15-25-20-41(21-31(44)42(25)29)30(43)17-14-22-8-3-2-4-9-22/h2-13,18,25,27,29H,14-17,19-21H2,1H3,(H3,36,37)(H,39,46)	AWCMDTMSPRXSSZ-UHFFFAOYSA-N	50076014	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-1-(3-carbamimidoyl-benzyl)-2-(1-methyl-1H-benzoimidazol-2-yl)-2-oxo-ethyl]-amide::CHEMBL168411	Prothrombin	Homo sapiens		 450							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076014&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			44381063	103969012		CHEMBL168411					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132314	Cc1nc(sc1CCO)C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1	InChI=1S/C29H39N7O5S/c1-18-23(13-15-37)42-28(33-18)26(40)21(8-5-14-32-29(30)31)34-27(41)22-11-10-20-16-35(17-25(39)36(20)22)24(38)12-9-19-6-3-2-4-7-19/h2-4,6-7,20-22,37H,5,8-17H2,1H3,(H,34,41)(H4,30,31,32)	OFNBWUOTBUVGEV-UHFFFAOYSA-N	50076022	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid {(S)-4-guanidino-1-[5-(2-hydroxy-ethyl)-4-methyl-thiazole-2-carbonyl]-butyl}-amide::CHEMBL355428	Prothrombin	Homo sapiens		 15							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076022	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076022&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			44380699	103969018		CHEMBL355428					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132315	NC(=N)NCCC[C@H](NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1)C(=O)c1ccccn1	InChI=1S/C28H35N7O4/c29-28(30)32-16-6-10-22(26(38)21-9-4-5-15-31-21)33-27(39)23-13-12-20-17-34(18-25(37)35(20)23)24(36)14-11-19-7-2-1-3-8-19/h1-5,7-9,15,20,22-23H,6,10-14,16-18H2,(H,33,39)(H4,29,30,32)	QXCKDSSZBUCQET-UHFFFAOYSA-N	50076020	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-4-guanidino-1-(pyridine-2-carbonyl)-butyl]-amide::(6S,8aS)-N-((S)-5-guanidino-1-oxo-1-(pyridin-2-yl)pentan-2-yl)-4-oxo-2-(3-phenylpropanoyl)-octahydropyrrolo[1,2-a]pyrazine-6-carboxamide::CHEMBL169946	Prothrombin	Homo sapiens		 340							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076020	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076020&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			44380674	103969017		CHEMBL169946					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132316	Cc1csc(n1)C(=O)C(CCCNC(N)=N)NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1	InChI=1S/C27H35N7O4S/c1-17-16-39-26(31-17)24(37)20(8-5-13-30-27(28)29)32-25(38)21-11-10-19-14-33(15-23(36)34(19)21)22(35)12-9-18-6-3-2-4-7-18/h2-4,6-7,16,19-21H,5,8-15H2,1H3,(H,32,38)(H4,28,29,30)	ALLMDIRYOKTDHH-UHFFFAOYSA-N	50076015	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [4-guanidino-1-(4-methyl-thiazole-2-carbonyl)-butyl]-amide::CHEMBL169067	Prothrombin	Homo sapiens		 44							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076015	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076015&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			44380662	103969013		CHEMBL169067					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132317	NC(=N)c1cccc(CC(NC(=O)[C@@H]2CC[C@H]3CN(CC(=O)N23)C(=O)CCc2ccccc2)C(=O)c2nc3ccccc3s2)c1	InChI=1S/C34H34N6O4S/c35-32(36)23-10-6-9-22(17-23)18-26(31(43)34-38-25-11-4-5-12-28(25)45-34)37-33(44)27-15-14-24-19-39(20-30(42)40(24)27)29(41)16-13-21-7-2-1-3-8-21/h1-12,17,24,26-27H,13-16,18-20H2,(H3,35,36)(H,37,44)	GOBFKUOZUDEDMD-UHFFFAOYSA-N	50076013	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [2-benzothiazol-2-yl-1-(3-carbamimidoyl-benzyl)-2-oxo-ethyl]-amide::CHEMBL166543	Serine protease 1	Homo sapiens		 970							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076013	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076013&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			44381062	103969011		CHEMBL166543					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132318	Cc1nc(sc1CCO)C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1	InChI=1S/C29H39N7O5S/c1-18-23(13-15-37)42-28(33-18)26(40)21(8-5-14-32-29(30)31)34-27(41)22-11-10-20-16-35(17-25(39)36(20)22)24(38)12-9-19-6-3-2-4-7-19/h2-4,6-7,20-22,37H,5,8-17H2,1H3,(H,34,41)(H4,30,31,32)	OFNBWUOTBUVGEV-UHFFFAOYSA-N	50076022	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid {(S)-4-guanidino-1-[5-(2-hydroxy-ethyl)-4-methyl-thiazole-2-carbonyl]-butyl}-amide::CHEMBL355428	Serine protease 1	Homo sapiens		 12							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076022	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076022&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			44380699	103969018		CHEMBL355428					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132319	NCCCC[C@H](NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1)C(=O)c1nccs1	InChI=1S/C26H33N5O4S/c27-13-5-4-8-20(24(34)26-28-14-15-36-26)29-25(35)21-11-10-19-16-30(17-23(33)31(19)21)22(32)12-9-18-6-2-1-3-7-18/h1-3,6-7,14-15,19-21H,4-5,8-13,16-17,27H2,(H,29,35)	UCMGNZDFXFVZPC-UHFFFAOYSA-N	50076023	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-5-amino-1-(thiazole-2-carbonyl)-pentyl]-amide::CHEMBL355060	Serine protease 1	Homo sapiens		 14							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076023	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076023&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			44381104	103969019		CHEMBL355060					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132320	[#6]-n1ccnc1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6@H]-2-[#6]-[#7](-[#6]-[#6](=O)-[#7]-1-2)-[#6](=O)-[#6]-[#6]-c1ccccc1	InChI=1S/C27H10N8O4/c1-33-15-14-30-25(33)24(38)20(8-5-13-31-27(28)29)32-26(39)21-11-10-19-16-34(17-23(37)35(19)21)22(36)12-9-18-6-3-2-4-7-18/h2-4,6-7,14-15,19-21H	HUXGNFSKJFYXEL-UHFFFAOYSA-N	50228717	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-4-guanidino-1-(1-methyl-1H-imidazole-2-carbonyl)-butyl]-amide::(6S,8aS)-N-((S)-5-guanidino-1-(1-methyl-1H-imidazol-2-yl)-1-oxopentan-2-yl)-4-oxo-2-(3-phenylpropanoyl)-octahydropyrrolo[1,2-a]pyrazine-6-carboxamide::CHEMBL256030	Prothrombin	Homo sapiens		 2370							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50228717	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50228717&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			44453904	104097950		CHEMBL256030					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132321	NCCCC[C@H](NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1)C(=O)c1nccs1	InChI=1S/C26H33N5O4S/c27-13-5-4-8-20(24(34)26-28-14-15-36-26)29-25(35)21-11-10-19-16-30(17-23(33)31(19)21)22(32)12-9-18-6-2-1-3-7-18/h1-3,6-7,14-15,19-21H,4-5,8-13,16-17,27H2,(H,29,35)	UCMGNZDFXFVZPC-UHFFFAOYSA-N	50076023	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-5-amino-1-(thiazole-2-carbonyl)-pentyl]-amide::CHEMBL355060	Prothrombin	Homo sapiens		 77							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076023	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076023&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			44381104	103969019		CHEMBL355060					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132322	[#6]-n1c(nc2ccccc12)-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6@H]-2-[#6]-[#7](-[#6]-[#6](=O)-[#7]-1-2)-[#6](=O)-[#6]-[#6]-c1ccccc1	InChI=1S/C31H12N8O4/c1-37-24-12-6-5-10-22(24)35-29(37)28(42)23(11-7-17-34-31(32)33)36-30(43)25-15-14-21-18-38(19-27(41)39(21)25)26(40)16-13-20-8-3-2-4-9-20/h2-6,8-10,12,21,23,25H	AWTZHJRNZLSQHN-UHFFFAOYSA-N	50228718	(6S,8aS)-N-((S)-5-guanidino-1-(1-methyl-1H-benzo[d]imidazol-2-yl)-1-oxopentan-2-yl)-4-oxo-2-(3-phenylpropanoyl)-octahydropyrrolo[1,2-a]pyrazine-6-carboxamide::(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-4-guanidino-1-(1-methyl-1H-benzoimidazole-2-carbonyl)-butyl]-amide::CHEMBL256396	Serine protease 1	Homo sapiens		 3360							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50228718	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50228718&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			44453663	104097951		CHEMBL256396					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50132323	Cn1c(nc2ccccc12)C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1	InChI=1S/C31H38N6O4/c1-35-25-13-6-5-11-23(25)33-30(35)29(40)24(12-7-8-18-32)34-31(41)26-16-15-22-19-36(20-28(39)37(22)26)27(38)17-14-21-9-3-2-4-10-21/h2-6,9-11,13,22,24,26H,7-8,12,14-20,32H2,1H3,(H,34,41)	XRXUBCLWSQSKHT-UHFFFAOYSA-N	50076019	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-5-amino-1-(1-methyl-1H-benzoimidazole-2-carbonyl)-pentyl]-amide::CHEMBL168280	Prothrombin	Homo sapiens		 2050							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076019	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076019&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			44380740	103969016		CHEMBL168280					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50577711	NC(=N)N1CCCC(C[C@H](NC(=O)[C@@H]2CC[C@H]3CN(CC(=O)N23)C(=O)CCc2ccccc2)C(=O)c2nc3ccccc3s2)C1	InChI=1S/C33H39N7O4S/c34-33(35)38-16-6-9-22(18-38)17-25(30(43)32-37-24-10-4-5-11-27(24)45-32)36-31(44)26-14-13-23-19-39(20-29(42)40(23)26)28(41)15-12-21-7-2-1-3-8-21/h1-5,7-8,10-11,22-23,25-26H,6,9,12-20H2,(H3,34,35)(H,36,44)	XCVRAVMOZULGSZ-UHFFFAOYSA-N	50076017	(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-2-benzothiazol-2-yl-1-(1-carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-amide::CHEMBL433911	Prothrombin	Homo sapiens		<1							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076017	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076017&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			10009177	103969015		CHEMBL433911					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50577712	[H][C@@]12CC[C@H](N1C(=O)CN(C2)C(=O)CCc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1	InChI=1S/C30H35N7O4S/c31-30(32)33-16-6-10-22(27(40)29-35-21-9-4-5-11-24(21)42-29)34-28(41)23-14-13-20-17-36(18-26(39)37(20)23)25(38)15-12-19-7-2-1-3-8-19/h1-5,7-9,11,20,22-23H,6,10,12-18H2,(H,34,41)(H4,31,32,33)	ORLJEHHINDEMRP-UHFFFAOYSA-N	50217503	CHEMBL352928	Prothrombin	Homo sapiens		<1							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=334&target=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217503&enzyme=Prothrombin&column=ki&startPg=0&Increment=50&submit=Search			44380663	376225332		CHEMBL352928					1	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE	9CMO,9CLS,9CLN,8RTN,8UF7,4O03,4NZQ,1XM1,1JWT,1HAG,1DOJ,1NU9,6V5T,2BDY,1D9I,3C1K,1ZRB,1ZGV,1ZGI,1Z71,1TA6,1TA2,1SL3,1NT1,1NM6,1G37,1D6W,9R8Q,9H79,9H5N,9C50,8BW5,8ASF,8ASE,7ZKO,7ZKN,7ZKM,7ZKL,7PHX,7NTU,7MJ5,7KME,7AC9,6ZV8,6ZV7,6ZUX,6ZUW,6ZUU,6ZUN,6ZUH,6ZGO,6Z8X,6Z8W,6Z8V,6Z48,6YSX,6YSJ,6YQV,6YN3,6YMP,6YHJ,6YHG,6YB6,6Y9H,6Y02,6V64,6TKL,6TKJ,6TKI,6TKH,6TKG,6TDT,6T8A,6T89,6T7H,6T57,6T56,6T55,6T54,6T53,6T52,6T4A,6T3Q,6T3M,6I51,6HSX,6GWE,6GN7,6GBW,6EVV,6EO9,6EO8,6EO7,6EO6,6CYM,5NHU,5LPD,5LCE,5L6N,5JZY,5JFD,5GIM,5GDS,5EW2,5EW1,5E8E,5CMX,4YES,4UD9,4THN,4LZ4,4LZ1,4LXB,4I7Y,4HTC,4E7R,4E06,4E05,4DII,4DIH,4CH8,4CH2,4BOH,4BAQ,4BAO,4BAN,4BAM,4BAK,4BAH,3VXF,3VXE,3UWJ,3UTU,3U9A,3U98,3U8T,3U8R,3U8O,3U69,3TU7,3T5F,3SV2,3SI4,3SI3,3SHC,3SHA,3RMO,3RMN,3RMM,3RML,3RM2,3RM0,3RLY,3RLW,3QX5,3QWC,3QTV,3QTO,3QLP,3PMH,3P70,3P6Z,3P17,3LDX,3HTC,3HAT,3F68,3EQ0,3EGK,3E6P,3DUX,3DT0,3DHK,3DA9,3D49,3C27,3BF6,3B23,2ZO3,2ZNK,2ZIQ,2ZI2,2ZHW,2ZHQ,2ZHF,2ZHE,2ZGX,2ZGB,2ZG0,2ZFR,2ZFQ,2ZFP,2ZFF,2ZF0,2ZDV,2ZDA,2ZC9,2UUK,2UUJ,2UUF,2R2M,2JH6,2JH5,2JH0,2HPQ,2HPP,2HGT,2H9T,2GDE,2FES,2FEQ,2C93,2C90,2C8Z,2C8Y,2C8X,2C8W,2BXU,2BXT,2BVX,2BVS,2ANK,2AFQ,2A45,2A2X,1XMN,1WAY,1W7G,1UVS,1UMA,1TOM,1TMU,1TMT,1TMB,1THS,1THR,1TBZ,1T4V,1T4U,1SR5,1QJ7,1QJ6,1QJ1,1QHR,1QBV,1PPB,1P8V,1OYT,1OOK,1O5G,1O2G,1O0D,1NZQ,1NU7,1NRS,1NRR,1NRQ,1NRP,1NRO,1NRN,1NO9,1MUE,1MU8,1MU6,1LHG,1LHF,1LHE,1LHD,1LHC,1KTT,1KTS,1K22,1K21,1IHT,1IHS,1HXF,1HXE,1HUT,1HLT,1HGT,1HDT,1HBT,1HAP,1HAO,1HAI,1HAH,1G32,1G30,1FPH,1FPC,1DWE,1DWD,1DWC,1DWB,1DIT,1DE7,1D4P,1D3T,1D3Q,1D3P,1CA8,1C5O,1C5N,1C5L,1C1W,1C1V,1C1U,1BMN,1BMM,1BCU,1BB0,1BA8,1B5G,1AY6,1AWH,1AWF,1AIX,1AI8,1AHT,1AFE,1AE8,1AD8,1ABJ,1ABI,1A61,1A5G,1A4W,1A46,1A3E,1A3B,1A2C,6PXJ,6ZUG,5DO4,5AHG,5AFZ,5AFY,5AF9,5A2M,4UFG,4UFF,4UFE,4UFD,4UEH,4UE7,4UDW,3DD2,2PW8,1SB1,1GJ5,1GJ4,4LOY,4AZ2,4AYY,4AYV,4AX9,3BIV,3BIU	Prothrombin	THRB_HUMAN	P00734	B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50577713	NC(=N)NCCC[C@H](NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1)C(=O)c1nccs1	InChI=1S/C26H33N7O4S/c27-26(28)30-12-4-7-19(23(36)25-29-13-14-38-25)31-24(37)20-10-9-18-15-32(16-22(35)33(18)20)21(34)11-8-17-5-2-1-3-6-17/h1-3,5-6,13-14,18-20H,4,7-12,15-16H2,(H,31,37)(H4,27,28,30)	LAGUWJUZJRIYRI-UHFFFAOYSA-N	50072740	(S)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [4-guanidino-1-((S)-thiazole-2-carbonyl)-butyl]-amide::(6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-4-guanidino-1-(thiazole-2-carbonyl)-butyl]-amide::(6S,8aS)-N-((S)-5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-yl)-4-oxo-2-(3-phenylpropanoyl)-octahydropyrrolo[1,2-a]pyrazine-6-carboxamide::CHEMBL324413	Serine protease 1	Homo sapiens		<1							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072740	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072740&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			9958913	103966342		CHEMBL324413					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50577714	[H][C@@]12CC[C@H](N1C(=O)CN(C2)C(=O)CCc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1	InChI=1S/C30H35N7O4S/c31-30(32)33-16-6-10-22(27(40)29-35-21-9-4-5-11-24(21)42-29)34-28(41)23-14-13-20-17-36(18-26(39)37(20)23)25(38)15-12-19-7-2-1-3-8-19/h1-5,7-9,11,20,22-23H,6,10,12-18H2,(H,34,41)(H4,31,32,33)	ORLJEHHINDEMRP-UHFFFAOYSA-N	50217503	CHEMBL352928	Serine protease 1	Homo sapiens		<1							ChEMBL	10.1016/s0960-894x(99)00096-7	10.7270/Q25Q4V8V	10206546			Plummer, JS; Berryman, KA; Cai, C; Cody, WL; DiMaio, J; Doherty, AM; Eaton, S; Edmunds, JJ; Holland, DR; Lafleur, D; Levesque, S; Narasimhan, LS; Rubin, JR; Rapundalo, ST; Siddiqui, MA; Susser, A; St-Denis, Y; Winocour, P	6/22/1999	11/10/2009	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217503&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search			44380663	376225332		CHEMBL352928					1	MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS	8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY	Serine protease 1	TRY1_HUMAN	P07477	A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7