BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50011588 COC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C26H28N4O4S/c1-34-26(31)23-16-30(15-22(23)19-5-4-6-20(13-19)25(27)28)14-17-9-11-18(12-10-17)21-7-2-3-8-24(21)35(29,32)33/h2-13,22-23H,14-16H2,1H3,(H3,27,28)(H2,29,32,33) VXVOMLLAAQVNLR-UHFFFAOYSA-N 50076907 (3S,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid methyl ester with 2M of TFA::CHEMBL18225 Serine protease 1 Homo sapiens 63.0 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076907 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076907&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search 15463576 103969772 CHEMBL18225 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY Serine protease 1 TRY1_HUMAN P07477 A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7 50011589 COC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C26H28N4O4S/c1-34-26(31)23-16-30(15-22(23)19-5-4-6-20(13-19)25(27)28)14-17-9-11-18(12-10-17)21-7-2-3-8-24(21)35(29,32)33/h2-13,22-23H,14-16H2,1H3,(H3,27,28)(H2,29,32,33) VXVOMLLAAQVNLR-UHFFFAOYSA-N 50076907 (3S,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid methyl ester with 2M of TFA::CHEMBL18225 Coagulation factor X Homo sapiens 4.80 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076907 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076907&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 15463576 103969772 CHEMBL18225 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134114 COC(=O)[C@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@@H]1c1cccc(c1)C(N)=N InChI=1S/C26H28N4O4S/c1-34-26(31)23-16-30(15-22(23)19-5-4-6-20(13-19)25(27)28)14-17-9-11-18(12-10-17)21-7-2-3-8-24(21)35(29,32)33/h2-13,22-23H,14-16H2,1H3,(H3,27,28)(H2,29,32,33) VXVOMLLAAQVNLR-UHFFFAOYSA-N 50076908 (3R,4S)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid methyl ester with 2M of TFA::CHEMBL277994 Serine protease 1 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076908 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076908&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search 15463577 103969773 CHEMBL277994 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY Serine protease 1 TRY1_HUMAN P07477 A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7 50134115 COC(=O)[C@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@@H]1c1cccc(c1)C(N)=N InChI=1S/C26H28N4O4S/c1-34-26(31)23-16-30(15-22(23)19-5-4-6-20(13-19)25(27)28)14-17-9-11-18(12-10-17)21-7-2-3-8-24(21)35(29,32)33/h2-13,22-23H,14-16H2,1H3,(H3,27,28)(H2,29,32,33) VXVOMLLAAQVNLR-UHFFFAOYSA-N 50076908 (3R,4S)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid methyl ester with 2M of TFA::CHEMBL277994 Coagulation factor X Homo sapiens 13 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076908 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076908&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 15463577 103969773 CHEMBL277994 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134116 COC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C26H28N4O4S/c1-34-26(31)23-16-30(15-22(23)19-5-4-6-20(13-19)25(27)28)14-17-9-11-18(12-10-17)21-7-2-3-8-24(21)35(29,32)33/h2-13,22-23H,14-16H2,1H3,(H3,27,28)(H2,29,32,33) VXVOMLLAAQVNLR-UHFFFAOYSA-N 50076907 (3S,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid methyl ester with 2M of TFA::CHEMBL18225 Serine protease 1 Homo sapiens 63 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076907 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076907&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search 15463576 103969772 CHEMBL18225 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY Serine protease 1 TRY1_HUMAN P07477 A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7 50134117 COC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)O[C@H]1c1cccc(c1)C(N)=N InChI=1S/C25H26N4O5S/c1-33-25(30)21-15-29(34-23(21)18-5-4-6-19(13-18)24(26)27)14-16-9-11-17(12-10-16)20-7-2-3-8-22(20)35(28,31)32/h2-13,21,23H,14-15H2,1H3,(H3,26,27)(H2,28,31,32) IAUMSDOPUSJDIU-UHFFFAOYSA-N 50076909 (4R,5R)-5-(3-Carbamimidoyl-phenyl)-2-(2'-sulfamoyl-biphenyl-4-ylmethyl)-isoxazolidine-4-carboxylic acid methyl ester with 2M of TFA::CHEMBL279267 Serine protease 1 Homo sapiens 69 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076909 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076909&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search 44272562 103969774 CHEMBL279267 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY Serine protease 1 TRY1_HUMAN P07477 A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7 50134118 COC(=O)[C@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C26H28N4O4S/c1-34-26(31)23-16-30(15-22(23)19-5-4-6-20(13-19)25(27)28)14-17-9-11-18(12-10-17)21-7-2-3-8-24(21)35(29,32)33/h2-13,22-23H,14-16H2,1H3,(H3,27,28)(H2,29,32,33) VXVOMLLAAQVNLR-UHFFFAOYSA-N 50076910 (3R,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid methyl ester with 2M of TFA::CHEMBL19075 Serine protease 1 Homo sapiens >1600 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076910 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076910&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search 21968289 103969775 CHEMBL19075 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY Serine protease 1 TRY1_HUMAN P07477 A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7 50134119 CC(C)OC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)O[C@H]1c1cccc(c1)C(N)=N InChI=1S/C27H30N4O5S/c1-17(2)35-27(32)23-16-31(36-25(23)20-6-5-7-21(14-20)26(28)29)15-18-10-12-19(13-11-18)22-8-3-4-9-24(22)37(30,33)34/h3-14,17,23,25H,15-16H2,1-2H3,(H3,28,29)(H2,30,33,34) MPIZHZHLXIHDRD-UHFFFAOYSA-N 50076911 (4R,5R)-5-(3-Carbamimidoyl-phenyl)-2-(2'-sulfamoyl-biphenyl-4-ylmethyl)-isoxazolidine-4-carboxylic acid isopropyl ester with 2M of TFA::CHEMBL18578 Serine protease 1 Homo sapiens 93 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076911 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076911&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search 10075442 103969776 CHEMBL18578 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY Serine protease 1 TRY1_HUMAN P07477 A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7 50134120 CCCCOC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C29H34N4O4S/c1-2-3-15-37-29(34)26-19-33(18-25(26)22-7-6-8-23(16-22)28(30)31)17-20-11-13-21(14-12-20)24-9-4-5-10-27(24)38(32,35)36/h4-14,16,25-26H,2-3,15,17-19H2,1H3,(H3,30,31)(H2,32,35,36) GGSVKXFKOZNQGL-UHFFFAOYSA-N 50076912 (3S,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid butyl ester with 2M of TFA::CHEMBL429068 Coagulation factor X Homo sapiens 12 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076912 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076912&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 15463580 103969777 CHEMBL429068 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134121 NC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C25H27N5O3S/c26-24(27)19-5-3-4-18(12-19)21-14-30(15-22(21)25(28)31)13-16-8-10-17(11-9-16)20-6-1-2-7-23(20)34(29,32)33/h1-12,21-22H,13-15H2,(H3,26,27)(H2,28,31)(H2,29,32,33) XXSUCSCMAHVAOP-UHFFFAOYSA-N 50076913 (3S,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid amide with 2M of TFA::CHEMBL19038 Serine protease 1 Homo sapiens 500 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076913 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076913&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search 44272581 103969778 CHEMBL19038 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY Serine protease 1 TRY1_HUMAN P07477 A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7 50134122 NC(=N)c1cccc(c1)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1C(O)=O InChI=1S/C25H26N4O4S/c26-24(27)19-5-3-4-18(12-19)21-14-29(15-22(21)25(30)31)13-16-8-10-17(11-9-16)20-6-1-2-7-23(20)34(28,32)33/h1-12,21-22H,13-15H2,(H3,26,27)(H,30,31)(H2,28,32,33) ZFAKBHPIEAWJLD-UHFFFAOYSA-N 50076915 (3S,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid with 2M of TFA::CHEMBL435761 Coagulation factor X Homo sapiens 600 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076915 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076915&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 44272560 103969780 CHEMBL435761 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134123 CCOC(=O)[C@]1(C)CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C28H32N4O4S/c1-3-36-27(33)28(2)18-32(17-24(28)21-7-6-8-22(15-21)26(29)30)16-19-11-13-20(14-12-19)23-9-4-5-10-25(23)37(31,34)35/h4-15,24H,3,16-18H2,1-2H3,(H3,29,30)(H2,31,34,35) SVASUNOMHIDAOX-UHFFFAOYSA-N 50076914 (3S,4S)-4-(3-Carbamimidoyl-phenyl)-3-methyl-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid ethyl ester with 2M of TFA::CHEMBL275582 Serine protease 1 Homo sapiens 750 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076914 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076914&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search 15463581 103969779 CHEMBL275582 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY Serine protease 1 TRY1_HUMAN P07477 A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7 50134124 CCOC(=O)[C@]1(C)CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C28H32N4O4S/c1-3-36-27(33)28(2)18-32(17-24(28)21-7-6-8-22(15-21)26(29)30)16-19-11-13-20(14-12-19)23-9-4-5-10-25(23)37(31,34)35/h4-15,24H,3,16-18H2,1-2H3,(H3,29,30)(H2,31,34,35) SVASUNOMHIDAOX-UHFFFAOYSA-N 50076914 (3S,4S)-4-(3-Carbamimidoyl-phenyl)-3-methyl-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid ethyl ester with 2M of TFA::CHEMBL275582 Coagulation factor X Homo sapiens 26 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076914 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076914&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 15463581 103969779 CHEMBL275582 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134125 CC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C26H28N4O3S/c1-17(31)23-15-30(16-24(23)20-5-4-6-21(13-20)26(27)28)14-18-9-11-19(12-10-18)22-7-2-3-8-25(22)34(29,32)33/h2-13,23-24H,14-16H2,1H3,(H3,27,28)(H2,29,32,33) VNMJDJUMSGRWPP-UHFFFAOYSA-N 50076916 3-[(3R,4S)-4-Acetyl-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidin-3-yl]-benzamidine with 2M of TFA::CHEMBL18627 Coagulation factor X Homo sapiens 36 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076916 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076916&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 44272530 103969781 CHEMBL18627 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134127 NC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C25H27N5O3S/c26-24(27)19-5-3-4-18(12-19)21-14-30(15-22(21)25(28)31)13-16-8-10-17(11-9-16)20-6-1-2-7-23(20)34(29,32)33/h1-12,21-22H,13-15H2,(H3,26,27)(H2,28,31)(H2,29,32,33) XXSUCSCMAHVAOP-UHFFFAOYSA-N 50076913 (3S,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid amide with 2M of TFA::CHEMBL19038 Coagulation factor X Homo sapiens 150 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076913 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076913&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 44272581 103969778 CHEMBL19038 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134128 CCCCOC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C29H34N4O4S/c1-2-3-15-37-29(34)26-19-33(18-25(26)22-7-6-8-23(16-22)28(30)31)17-20-11-13-21(14-12-20)24-9-4-5-10-27(24)38(32,35)36/h4-14,16,25-26H,2-3,15,17-19H2,1H3,(H3,30,31)(H2,32,35,36) GGSVKXFKOZNQGL-UHFFFAOYSA-N 50076912 (3S,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid butyl ester with 2M of TFA::CHEMBL429068 Serine protease 1 Homo sapiens 110 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076912 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076912&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search 15463580 103969777 CHEMBL429068 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY Serine protease 1 TRY1_HUMAN P07477 A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7 50134129 COC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C26H28N4O4S/c1-34-26(31)23-16-30(15-22(23)19-5-4-6-20(13-19)25(27)28)14-17-9-11-18(12-10-17)21-7-2-3-8-24(21)35(29,32)33/h2-13,22-23H,14-16H2,1H3,(H3,27,28)(H2,29,32,33) VXVOMLLAAQVNLR-UHFFFAOYSA-N 50076907 (3S,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid methyl ester with 2M of TFA::CHEMBL18225 Coagulation factor X Homo sapiens 4.8 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076907 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076907&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 15463576 103969772 CHEMBL18225 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134130 CC(C)OC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)O[C@H]1c1cccc(c1)C(N)=N InChI=1S/C27H30N4O5S/c1-17(2)35-27(32)23-16-31(36-25(23)20-6-5-7-21(14-20)26(28)29)15-18-10-12-19(13-11-18)22-8-3-4-9-24(22)37(30,33)34/h3-14,17,23,25H,15-16H2,1-2H3,(H3,28,29)(H2,30,33,34) MPIZHZHLXIHDRD-UHFFFAOYSA-N 50076911 (4R,5R)-5-(3-Carbamimidoyl-phenyl)-2-(2'-sulfamoyl-biphenyl-4-ylmethyl)-isoxazolidine-4-carboxylic acid isopropyl ester with 2M of TFA::CHEMBL18578 Coagulation factor X Homo sapiens 1.8 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076911 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076911&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 10075442 103969776 CHEMBL18578 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134131 CC(C)OC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C28H32N4O4S/c1-18(2)36-28(33)25-17-32(16-24(25)21-6-5-7-22(14-21)27(29)30)15-19-10-12-20(13-11-19)23-8-3-4-9-26(23)37(31,34)35/h3-14,18,24-25H,15-17H2,1-2H3,(H3,29,30)(H2,31,34,35) NWNRXYIFWXPWLQ-UHFFFAOYSA-N 50076917 (3S,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid isopropyl ester with 2M of TFA::CHEMBL276782 Serine protease 1 Homo sapiens 98 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076917 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076917&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search 44272532 103969782 CHEMBL276782 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY Serine protease 1 TRY1_HUMAN P07477 A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7 50134132 COC(=O)CN(CCCc1ccc(cc1)-c1ccccc1S(N)(=O)=O)c1cccc(c1)C(N)=N InChI=1S/C25H28N4O4S/c1-33-24(30)17-29(21-8-4-7-20(16-21)25(26)27)15-5-6-18-11-13-19(14-12-18)22-9-2-3-10-23(22)34(28,31)32/h2-4,7-14,16H,5-6,15,17H2,1H3,(H3,26,27)(H2,28,31,32) WTZPFQZXGTVVPM-UHFFFAOYSA-N 50072448 {(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-biphenyl-4-yl)-propyl]-amino}-acetic acid methyl ester; TFA::CHEMBL18767 Coagulation factor X Homo sapiens 1.3 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072448 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072448&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 10054210 103966076 CHEMBL18767 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134133 CC(C)OC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C28H32N4O4S/c1-18(2)36-28(33)25-17-32(16-24(25)21-6-5-7-22(14-21)27(29)30)15-19-10-12-20(13-11-19)23-8-3-4-9-26(23)37(31,34)35/h3-14,18,24-25H,15-17H2,1-2H3,(H3,29,30)(H2,31,34,35) NWNRXYIFWXPWLQ-UHFFFAOYSA-N 50076917 (3S,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid isopropyl ester with 2M of TFA::CHEMBL276782 Coagulation factor X Homo sapiens 5.8 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076917 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076917&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 44272532 103969782 CHEMBL276782 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134134 NC(=N)c1cccc(c1)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@@H]1C(O)=O InChI=1S/C25H26N4O4S/c26-24(27)19-5-3-4-18(12-19)21-14-29(15-22(21)25(30)31)13-16-8-10-17(11-9-16)20-6-1-2-7-23(20)34(28,32)33/h1-12,21-22H,13-15H2,(H3,26,27)(H,30,31)(H2,28,32,33) ZFAKBHPIEAWJLD-UHFFFAOYSA-N 50076918 (3R,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid with 2M of TFA::CHEMBL277366 Coagulation factor X Homo sapiens 460 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076918 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076918&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 15463579 103969783 CHEMBL277366 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134135 CC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C26H28N4O3S/c1-17(31)23-15-30(16-24(23)20-5-4-6-21(13-20)26(27)28)14-18-9-11-19(12-10-18)22-7-2-3-8-25(22)34(29,32)33/h2-13,23-24H,14-16H2,1H3,(H3,27,28)(H2,29,32,33) VNMJDJUMSGRWPP-UHFFFAOYSA-N 50076916 3-[(3R,4S)-4-Acetyl-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidin-3-yl]-benzamidine with 2M of TFA::CHEMBL18627 Serine protease 1 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076916 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1529&target=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076916&enzyme=Serine+protease+1&column=ki&startPg=0&Increment=50&submit=Search 44272530 103969781 CHEMBL18627 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 8ZJ4,8ZIY,8ZIV,8ZI4,8H3S,1TRN,2RA3,4WWY Serine protease 1 TRY1_HUMAN P07477 A1A509 A6NJ71 B2R5I5 Q5NV57 Q7M4N3 Q7M4N4 Q92955 Q9HAN4 Q9HAN5 Q9HAN6 Q9HAN7 50134136 COC(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)O[C@H]1c1cccc(c1)C(N)=N InChI=1S/C25H26N4O5S/c1-33-25(30)21-15-29(34-23(21)18-5-4-6-19(13-18)24(26)27)14-16-9-11-17(12-10-16)20-7-2-3-8-22(20)35(28,31)32/h2-13,21,23H,14-15H2,1H3,(H3,26,27)(H2,28,31,32) IAUMSDOPUSJDIU-UHFFFAOYSA-N 50076909 (4R,5R)-5-(3-Carbamimidoyl-phenyl)-2-(2'-sulfamoyl-biphenyl-4-ylmethyl)-isoxazolidine-4-carboxylic acid methyl ester with 2M of TFA::CHEMBL279267 Coagulation factor X Homo sapiens 3.1 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076909 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076909&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 44272562 103969774 CHEMBL279267 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134137 COC(=O)CC1(CC(=NO1)c1cccc(c1)C(N)=N)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O |c:7| InChI=1S/C26H25N5O6S/c1-36-23(32)15-26(14-21(31-37-26)17-5-4-6-18(13-17)24(27)28)25(33)30-19-11-9-16(10-12-19)20-7-2-3-8-22(20)38(29,34)35/h2-13H,14-15H2,1H3,(H3,27,28)(H,30,33)(H2,29,34,35) QMEXGOMLMAXBEB-UHFFFAOYSA-N 50072445 CHEMBL139063::CHEMBL279628::[3-(3-Carbamimidoyl-phenyl)-5-(2'-sulfamoyl-biphenyl-4-ylcarbamoyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid methyl ester; TFA Coagulation factor X Homo sapiens 6.3 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072445 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072445&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 9936983 103966073 CHEMBL279628CHEMBL139063 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134138 COC(=O)[C@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C26H28N4O4S/c1-34-26(31)23-16-30(15-22(23)19-5-4-6-20(13-19)25(27)28)14-17-9-11-18(12-10-17)21-7-2-3-8-24(21)35(29,32)33/h2-13,22-23H,14-16H2,1H3,(H3,27,28)(H2,29,32,33) VXVOMLLAAQVNLR-UHFFFAOYSA-N 50076910 (3R,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid methyl ester with 2M of TFA::CHEMBL19075 Coagulation factor X Homo sapiens 170 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076910 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076910&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 21968289 103969775 CHEMBL19075 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340 50134139 CN(C)C(=O)[C@@H]1CN(Cc2ccc(cc2)-c2ccccc2S(N)(=O)=O)C[C@H]1c1cccc(c1)C(N)=N InChI=1S/C27H31N5O3S/c1-31(2)27(33)24-17-32(16-23(24)20-6-5-7-21(14-20)26(28)29)15-18-10-12-19(13-11-18)22-8-3-4-9-25(22)36(30,34)35/h3-14,23-24H,15-17H2,1-2H3,(H3,28,29)(H2,30,34,35) LQIYKFLTUSNOOI-UHFFFAOYSA-N 50076919 (3S,4R)-4-(3-Carbamimidoyl-phenyl)-1-(2'-sulfamoyl-biphenyl-4-ylmethyl)-pyrrolidine-3-carboxylic acid dimethylamide with 2M of TFA::CHEMBL19090 Coagulation factor X Homo sapiens 400 ChEMBL 10.1016/s0960-894x(99)00164-x 10.7270/Q20V8BZZ 10328312 Fevig, JM; Buriak, J; Stouten, PF; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR 8/3/1999 11/10/2009 Dupont Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076919 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1341&target=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076919&enzyme=Coagulation+factor+X&column=ki&startPg=0&Increment=50&submit=Search 15463578 103969784 CHEMBL19090 1 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK 9L6S,9CM9,9CM2,9CLI,8EOK,4ZHA,4ZH8,4Y7B,4Y7A,4Y79,4Y76,4Y71,4Y6D,4BTU,4BTT,4BTI,4A7I,2Y82,2Y81,2Y80,2Y7Z,2Y7X,2WYJ,2WYG,2VH6,2VH0,2UWP,2UWO,2UWL,2J95,2J94,2J4I,2J38,2J34,2J2U,2CJI,2BOH,1P0S,1NFY,1NFX,1NFW,1NFU,1LQD,1LPZ,1LPK,1LPG,1KSN,1F0S,1F0R,1EZQ,7TPP,1FAX,1C5M,9I24,2BQW,2BQ7,2BQ6,7AHU,3KL6,2XC5,2XC4,2XC0,2XBY,2XBX,2XBW,1HCG,3SW2,3K9X,3HPT,3ENS,2P3F,1XKB,1XKA,1IQN,1IQM,1IQL,1IQK,1IQJ,1IQI,1IQH,1IQG,1IQF,1IQE,1IOE,1G2M,1G2L,9CTH,9R8R,5K0H,3M37,3M36,3LIW,3KQE,3KQD,3KQC,3KQB,3FFG,3CS7,3CEN,2W3K,2W3I,2W26,2RA0,2Q1J,2PR3,2PHB,2P95,2P94,2P93,2P16,2G00,2FZZ,2BMG,1Z6E,1FJS,3TK6,3TK5,3Q3K,3IIT,2P3U,2P3T,2H9E,2EI8,2EI7,2EI6,2D1J,1WU1,1V3X,1MQ6,1MQ5,5VOF,5VOE,9P0X Coagulation factor X FA10_HUMAN P00742 Q14340