BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 306614 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 1 Homo sapiens 5e+2 8.0000 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801335 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1967&target=Histone+deacetylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+1&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 306615 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 2 Homo sapiens 1e+2 8.0000 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801335 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2482&target=Histone+deacetylase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+2&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 306616 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 3 Homo sapiens 6e+1 8.0000 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801335 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1995&target=Histone+deacetylase+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+3&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 306617 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 8 Homo sapiens 1.5e+3 8.0000 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801335 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1996&target=Histone+deacetylase+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+8&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 3SFH,3SFF,6ODC,6ODB,6ODA,5FCW,1W22,1VKG,1T69,1T67,1T64,3RQD,3MZ3,3F0R,3F07,5VI6 Histone deacetylase 8 HDAC8_HUMAN Q9BY41 A6ND12 A6ND61 A6NET3 A6NJR3 A8MQ62 B4DKN0 B4DV22 Q86VC8 Q9NP76 Q9NYH4 306618 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 6 Homo sapiens 9.1e+3 8.0000 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801335 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2556&target=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH 5EDU,7ZYU,3PHD,3GV4 Protein deacetylase HDAC6 HDAC6_HUMAN Q9UBN7 O94975 Q6NT75 Q7L3E5 Q96CY0 306619 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Polyamine deacetylase HDAC10 Homo sapiens 1.53e+4 8.0000 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801335 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2538&target=Polyamine+deacetylase+HDAC10&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Polyamine+deacetylase+HDAC10&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MGTALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQDVTAVPMSPSSHSPEGRPPPLLPGGPVCKAAASAPSSLLDQPCLCPAPSVRTAVALTTPDITLVLPPDVIQQEASALREETEAWARPHESLAREEALTALGKLLYLLDGMLDGQVNSGIAATPASAAAATLDVAVRRGLSHGAQRLLCVALGQLDRPPDLAHDGRSLWLNIRGKEAAALSMFHVSTPLPVMTGGFLSCILGLVLPLAYGFQPDLVLVALGPGHGLQGPHAALLAAMLRGLAGGRVLALLEENSTPQLAGILARVLNGEAPPSLGPSSVASPEDVQALMYLRGQLEPQWKMLQCHPHLVA Polyamine deacetylase HDAC10 HDA10_HUMAN Q969S8 Q08AP4 Q6STF9 Q96P77 Q96P78 Q9H028 Q9UGX1 Q9UGX2 306620 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 11 Homo sapiens 4.45e+4 8.0000 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801335 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2640&target=Histone+deacetylase+11&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+11&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP Histone deacetylase 11 HDA11_HUMAN Q96DB2 B4DDK1 Q9H6I7 Q9H6X3 Q9NTC9 306621 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 4 Homo sapiens >1.00e+5 8.0000 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801335 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6107&target=Histone+deacetylase+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+4&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEEEPPL 2VQM,2VQJ,6FYZ,4CBT,7XUZ Histone deacetylase 4 HDAC4_HUMAN P56524 E9PGB9 F5GX36 Q86YH7 Q9UND6 306622 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 5 Homo sapiens >1.00e+5 8.0000 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801335 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6108&target=Histone+deacetylase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+5&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL Histone deacetylase 5 HDAC5_HUMAN Q9UQL6 C9JFV9 O60340 O60528 Q96DY4 306623 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 7 Homo sapiens >1.00e+5 8.0000 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801335 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2645&target=Histone+deacetylase+7&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+7&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MDLRVGQRPPVEPPPEPTLLALQRPQRLHHHLFLAGLQQQRSVEPMRLSMDTPMPELQVGPQEQELRQLLHKDKSKRSAVASSVVKQKLAEVILKKQQAALERTVHPNSPGIPYRTLEPLETEGATRSMLSSFLPPVPSLPSDPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKESAPPSLRRRPAETLGDSSPSSSSTPASGCSSPNDSEHGPNPILGSEALLGQRLRLQETSVAPFALPTVSLLPAITLGLPAPARADSDRRTHPTLGPRGPILGSPHTPLFLPHGLEPEAGGTLPSRLQPILLLDPSGSHAPLLTVPGLGPLPFHFAQSLMTTERLSGSGLHWPLSRTRSEPLPPSATAPPPPGPMQPRLEQLKTHVQVIKRSAKPSEKPRLRQIPSAEDLETDGGGPGQVVDDGLEHRELGHGQPEARGPAPLQQHPQVLLWEQQRLAGRLPRGSTGDTVLLPLAQGGHRPLSRAQSSPAAPASLSAPEPASQARVLSSSETPARTLPFTTGLIYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKPNLNAIRSLEAVIRVHSKYWGCMQRLASCPDSWVPRVPGADKEEVEAVTALASLSVGILAEDRPSEQLVEEEEPMNL 3ZNS,3ZNR,3C10,3C0Z,3C0Y Histone deacetylase 7 HDAC7_HUMAN Q8WUI4 B3KY08 B4DWI0 B4E0Q5 Q6P1W9 Q6W9G7 Q7Z4K2 Q7Z5I1 Q96K01 Q9BR73 Q9H7L0 Q9NW41 Q9NWA9 Q9NYK9 Q9UFU7 306624 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 9 Homo sapiens >1.00e+5 8.0000 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801335 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6112&target=Histone+deacetylase+9&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+9&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MHSMISSVDVKSEVPVGLEPISPLDLRTDLRMMMPVVDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHIKELLAIKQQQELLEKEQKLEQQRQEQEVERHRREQQLPPLRGKDRGRERAVASTEVKQKLQEFLLSKSATKDTPTNGKNHSVSRHPKLWYTAAHHTSLDQSSPPLSGTSPSYKYTLPGAQDAKDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGNVVTSFKKRMFEVTESSVSSSSPGSGPSSPNNGPTGSVTENETSVLPPTPHAEQMVSQQRILIHEDSMNLLSLYTSPSLPNITLGLPAVPSQLNASNSLKEKQKCETQTLRQGVPLPGQYGGSIPASSSHPHVTLEGKPPNSSHQALLQHLLLKEQMRQQKLLVAGGVPLHPQSPLATKERISPGIRGTHKLPRHRPLNRTQSAPLPQSTLAQLVIQQQHQQFLEKQKQYQQQIHMNKLLSKSIEQLKQPGSHLEEAEEELQGDQAMQEDRAPSSGNSTRSDSSACVDDTLGQVGAVKVKEEPVDSDEDAQIQEMESGEQAAFMQQPFLEPTHTRALSVRQAPLAAVGMDGLEKHRLVSRTHSSPAASVLPHPAMDRPLQPGSATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEACVNALLGNELEPLAEDILHQSPNMNAVISLQKIIEIQSMSLKFS Histone deacetylase 9 HDAC9_HUMAN Q9UKV0 A7E2F3 B7Z4I4 B7Z917 B7Z928 B7Z940 C9JS87 E7EX34 F8W9E0 O94845 O95028 Q2M2R6 Q86SL1 Q86US3 306625 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 4.6e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306626 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.33e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306627 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.9e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306628 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 6 Homo sapiens 9.09e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2556&target=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH 5EDU,7ZYU,3PHD,3GV4 Protein deacetylase HDAC6 HDAC6_HUMAN Q9UBN7 O94975 Q6NT75 Q7L3E5 Q96CY0 306629 CCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) BVQCFCYPFJOOAV-UHFFFAOYSA-N 163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010 Histone deacetylase 8 Homo sapiens 2.83e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1996&target=Histone+deacetylase+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163619&enzyme=Histone+deacetylase+8&column=ki&startPg=0&Increment=50&submit=Search 4596836 310305336 1 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 3SFH,3SFF,6ODC,6ODB,6ODA,5FCW,1W22,1VKG,1T69,1T67,1T64,3RQD,3MZ3,3F0R,3F07,5VI6 Histone deacetylase 8 HDAC8_HUMAN Q9BY41 A6ND12 A6ND61 A6NET3 A6NJR3 A8MQ62 B4DKN0 B4DV22 Q86VC8 Q9NP76 Q9NYH4 306630 CCCCNNC(=O)c1ccc(F)cc1 InChI=1S/C11H15FN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) YRLLWXIGAGZKFP-UHFFFAOYSA-N 163620 SR-3203::US10807944, Compound RLS2-306::US11731934, Compound RLS2-306 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.32e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163620 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163620&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 70438237 310305337 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306631 CCCCNNC(=O)c1ccc(F)cc1 InChI=1S/C11H15FN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) YRLLWXIGAGZKFP-UHFFFAOYSA-N 163620 SR-3203::US10807944, Compound RLS2-306::US11731934, Compound RLS2-306 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.51e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163620 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163620&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 70438237 310305337 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306632 CCCCNNC(=O)c1ccc(F)cc1 InChI=1S/C11H15FN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) YRLLWXIGAGZKFP-UHFFFAOYSA-N 163620 SR-3203::US10807944, Compound RLS2-306::US11731934, Compound RLS2-306 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.78e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163620 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163620&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 70438237 310305337 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306633 CCCCNNC(=O)c1ccc(OC(F)(F)F)cc1 InChI=1S/C12H15F3N2O2/c1-2-3-8-16-17-11(18)9-4-6-10(7-5-9)19-12(13,14)15/h4-7,16H,2-3,8H2,1H3,(H,17,18) JEEFFJUUDNJNDQ-UHFFFAOYSA-N 163621 SR-3204::US10807944, Compound RLS2-124::US11731934, Compound RLS2-124 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 8.86e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163621 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163621&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306434 310305338 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306634 CCCCNNC(=O)c1ccc(OC(F)(F)F)cc1 InChI=1S/C12H15F3N2O2/c1-2-3-8-16-17-11(18)9-4-6-10(7-5-9)19-12(13,14)15/h4-7,16H,2-3,8H2,1H3,(H,17,18) JEEFFJUUDNJNDQ-UHFFFAOYSA-N 163621 SR-3204::US10807944, Compound RLS2-124::US11731934, Compound RLS2-124 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 9.09e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163621 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163621&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306434 310305338 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306635 CCCCNNC(=O)c1ccc(OC(F)(F)F)cc1 InChI=1S/C12H15F3N2O2/c1-2-3-8-16-17-11(18)9-4-6-10(7-5-9)19-12(13,14)15/h4-7,16H,2-3,8H2,1H3,(H,17,18) JEEFFJUUDNJNDQ-UHFFFAOYSA-N 163621 SR-3204::US10807944, Compound RLS2-124::US11731934, Compound RLS2-124 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.35e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163621 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163621&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306434 310305338 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306636 CCCCNNC(=O)c1ccccc1 InChI=1S/C11H16N2O/c1-2-3-9-12-13-11(14)10-7-5-4-6-8-10/h4-8,12H,2-3,9H2,1H3,(H,13,14) ZYBWZQIGNAKZJX-UHFFFAOYSA-N 163622 SR-3205::US10807944, Compound RLS2-125::US11731934, Compound RLS2-125 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens >5.0e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163622 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163622&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 13718925 310305339 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306637 CCCCNNC(=O)c1ccccc1 InChI=1S/C11H16N2O/c1-2-3-9-12-13-11(14)10-7-5-4-6-8-10/h4-8,12H,2-3,9H2,1H3,(H,13,14) ZYBWZQIGNAKZJX-UHFFFAOYSA-N 163622 SR-3205::US10807944, Compound RLS2-125::US11731934, Compound RLS2-125 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens >5.0e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163622 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163622&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 13718925 310305339 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306638 CCCCNNC(=O)c1ccccc1 InChI=1S/C11H16N2O/c1-2-3-9-12-13-11(14)10-7-5-4-6-8-10/h4-8,12H,2-3,9H2,1H3,(H,13,14) ZYBWZQIGNAKZJX-UHFFFAOYSA-N 163622 SR-3205::US10807944, Compound RLS2-125::US11731934, Compound RLS2-125 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens >5.0e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163622 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163622&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 13718925 310305339 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306639 CCCCNNC(=O)c1ccc(OC)cc1 InChI=1S/C12H18N2O2/c1-3-4-9-13-14-12(15)10-5-7-11(16-2)8-6-10/h5-8,13H,3-4,9H2,1-2H3,(H,14,15) RFMNSSZOADXOBU-UHFFFAOYSA-N 163623 SR-3206::US10807944, Compound RLS2-126::US10870618, Compound 1a::US11731934, Compound RLS2-126 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.91e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163623 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163623&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306436 310305340 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306640 CCCCNNC(=O)c1ccc(OC)cc1 InChI=1S/C12H18N2O2/c1-3-4-9-13-14-12(15)10-5-7-11(16-2)8-6-10/h5-8,13H,3-4,9H2,1-2H3,(H,14,15) RFMNSSZOADXOBU-UHFFFAOYSA-N 163623 SR-3206::US10807944, Compound RLS2-126::US10870618, Compound 1a::US11731934, Compound RLS2-126 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 2.52e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163623 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163623&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306436 310305340 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306641 CCCCNNC(=O)c1ccc(OC)cc1 InChI=1S/C12H18N2O2/c1-3-4-9-13-14-12(15)10-5-7-11(16-2)8-6-10/h5-8,13H,3-4,9H2,1-2H3,(H,14,15) RFMNSSZOADXOBU-UHFFFAOYSA-N 163623 SR-3206::US10807944, Compound RLS2-126::US10870618, Compound 1a::US11731934, Compound RLS2-126 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 4.3e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163623 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163623&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306436 310305340 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306642 CCCCNNC(=O)c1ccc(cc1)N(C)C InChI=1S/C13H21N3O/c1-4-5-10-14-15-13(17)11-6-8-12(9-7-11)16(2)3/h6-9,14H,4-5,10H2,1-3H3,(H,15,17) GBPRHUHCZVADPX-UHFFFAOYSA-N 163624 SR-3208::US10807944, Compound RLS2-131::US11731934, Compound RLS2-131 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 2.3e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163624 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163624&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306440 310305341 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306643 CCCCNNC(=O)c1ccc(cc1)N(C)C InChI=1S/C13H21N3O/c1-4-5-10-14-15-13(17)11-6-8-12(9-7-11)16(2)3/h6-9,14H,4-5,10H2,1-3H3,(H,15,17) GBPRHUHCZVADPX-UHFFFAOYSA-N 163624 SR-3208::US10807944, Compound RLS2-131::US11731934, Compound RLS2-131 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 8.8e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163624 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163624&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306440 310305341 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306644 CCCCNNC(=O)c1ccc(cc1)N(C)C InChI=1S/C13H21N3O/c1-4-5-10-14-15-13(17)11-6-8-12(9-7-11)16(2)3/h6-9,14H,4-5,10H2,1-3H3,(H,15,17) GBPRHUHCZVADPX-UHFFFAOYSA-N 163624 SR-3208::US10807944, Compound RLS2-131::US11731934, Compound RLS2-131 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.2e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163624 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163624&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306440 310305341 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306645 CCCCNNC(=O)c1ccc(cc1)N(C)C InChI=1S/C13H21N3O/c1-4-5-10-14-15-13(17)11-6-8-12(9-7-11)16(2)3/h6-9,14H,4-5,10H2,1-3H3,(H,15,17) GBPRHUHCZVADPX-UHFFFAOYSA-N 163624 SR-3208::US10807944, Compound RLS2-131::US11731934, Compound RLS2-131 Histone deacetylase 6 Homo sapiens 9.57e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163624 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2556&target=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163624&enzyme=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search 71306440 310305341 1 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH 5EDU,7ZYU,3PHD,3GV4 Protein deacetylase HDAC6 HDAC6_HUMAN Q9UBN7 O94975 Q6NT75 Q7L3E5 Q96CY0 306646 CCCCNNC(=O)c1ccc(cc1)N(C)C InChI=1S/C13H21N3O/c1-4-5-10-14-15-13(17)11-6-8-12(9-7-11)16(2)3/h6-9,14H,4-5,10H2,1-3H3,(H,15,17) GBPRHUHCZVADPX-UHFFFAOYSA-N 163624 SR-3208::US10807944, Compound RLS2-131::US11731934, Compound RLS2-131 Histone deacetylase 8 Homo sapiens 7.2e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163624 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1996&target=Histone+deacetylase+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163624&enzyme=Histone+deacetylase+8&column=ki&startPg=0&Increment=50&submit=Search 71306440 310305341 1 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 3SFH,3SFF,6ODC,6ODB,6ODA,5FCW,1W22,1VKG,1T69,1T67,1T64,3RQD,3MZ3,3F0R,3F07,5VI6 Histone deacetylase 8 HDAC8_HUMAN Q9BY41 A6ND12 A6ND61 A6NET3 A6NJR3 A8MQ62 B4DKN0 B4DV22 Q86VC8 Q9NP76 Q9NYH4 306647 CCCCNNC(=O)c1ccc(Cl)cc1 InChI=1S/C11H15ClN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) SOFXANVWFFBJSR-UHFFFAOYSA-N 163625 SR-3210::US10807944, Compound RLS2-133::US11731934, Compound RLS2-133 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 3.0e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163625 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163625&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 54316037 310305342 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306648 CCCCNNC(=O)c1ccc(Cl)cc1 InChI=1S/C11H15ClN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) SOFXANVWFFBJSR-UHFFFAOYSA-N 163625 SR-3210::US10807944, Compound RLS2-133::US11731934, Compound RLS2-133 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 3.8e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163625 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163625&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 54316037 310305342 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306649 CCCCNNC(=O)c1ccc(Cl)cc1 InChI=1S/C11H15ClN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15) SOFXANVWFFBJSR-UHFFFAOYSA-N 163625 SR-3210::US10807944, Compound RLS2-133::US11731934, Compound RLS2-133 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 2.5e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163625 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163625&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 54316037 310305342 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306650 CCCCNNC(=O)c1ccc(cc1)C(C)(C)C InChI=1S/C15H24N2O/c1-5-6-11-16-17-14(18)12-7-9-13(10-8-12)15(2,3)4/h7-10,16H,5-6,11H2,1-4H3,(H,17,18) SKZFNTOJPSTVDI-UHFFFAOYSA-N 163626 SR-3302::US10807944, Compound RLS2-211::US11731934, Compound RLS2-211 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.9e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163626 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163626&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094788 310305343 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306651 CCCCNNC(=O)c1ccc(cc1)C(C)(C)C InChI=1S/C15H24N2O/c1-5-6-11-16-17-14(18)12-7-9-13(10-8-12)15(2,3)4/h7-10,16H,5-6,11H2,1-4H3,(H,17,18) SKZFNTOJPSTVDI-UHFFFAOYSA-N 163626 SR-3302::US10807944, Compound RLS2-211::US11731934, Compound RLS2-211 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.04e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163626 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163626&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094788 310305343 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306652 CCCCNNC(=O)c1ccc(cc1)C(C)(C)C InChI=1S/C15H24N2O/c1-5-6-11-16-17-14(18)12-7-9-13(10-8-12)15(2,3)4/h7-10,16H,5-6,11H2,1-4H3,(H,17,18) SKZFNTOJPSTVDI-UHFFFAOYSA-N 163626 SR-3302::US10807944, Compound RLS2-211::US11731934, Compound RLS2-211 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 7e+1 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163626 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163626&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094788 310305343 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306653 CCCCNNC(=O)c1ccc(cc1)C(C)(C)C InChI=1S/C15H24N2O/c1-5-6-11-16-17-14(18)12-7-9-13(10-8-12)15(2,3)4/h7-10,16H,5-6,11H2,1-4H3,(H,17,18) SKZFNTOJPSTVDI-UHFFFAOYSA-N 163626 SR-3302::US10807944, Compound RLS2-211::US11731934, Compound RLS2-211 Histone deacetylase 6 Homo sapiens 6.83e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163626 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2556&target=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163626&enzyme=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search 117094788 310305343 1 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH 5EDU,7ZYU,3PHD,3GV4 Protein deacetylase HDAC6 HDAC6_HUMAN Q9UBN7 O94975 Q6NT75 Q7L3E5 Q96CY0 306654 CCCCNNC(=O)c1ccc(cc1)C(C)(C)C InChI=1S/C15H24N2O/c1-5-6-11-16-17-14(18)12-7-9-13(10-8-12)15(2,3)4/h7-10,16H,5-6,11H2,1-4H3,(H,17,18) SKZFNTOJPSTVDI-UHFFFAOYSA-N 163626 SR-3302::US10807944, Compound RLS2-211::US11731934, Compound RLS2-211 Histone deacetylase 8 Homo sapiens 4.9e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163626 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1996&target=Histone+deacetylase+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163626&enzyme=Histone+deacetylase+8&column=ki&startPg=0&Increment=50&submit=Search 117094788 310305343 1 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 3SFH,3SFF,6ODC,6ODB,6ODA,5FCW,1W22,1VKG,1T69,1T67,1T64,3RQD,3MZ3,3F0R,3F07,5VI6 Histone deacetylase 8 HDAC8_HUMAN Q9BY41 A6ND12 A6ND61 A6NET3 A6NJR3 A8MQ62 B4DKN0 B4DV22 Q86VC8 Q9NP76 Q9NYH4 306655 CCCCNNC(=O)c1ccc(C[N-][N+]#N)cc1 InChI=1S/C12H17N5O/c1-2-3-8-14-16-12(18)11-6-4-10(5-7-11)9-15-17-13/h4-7,14H,2-3,8-9H2,1H3,(H,16,18) NRJRDICLAPALFB-UHFFFAOYSA-N 163627 SR-3459 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 3.2e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163627 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163627&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094789 310305344 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306656 CCCCNNC(=O)c1ccc(C[N-][N+]#N)cc1 InChI=1S/C12H17N5O/c1-2-3-8-14-16-12(18)11-6-4-10(5-7-11)9-15-17-13/h4-7,14H,2-3,8-9H2,1H3,(H,16,18) NRJRDICLAPALFB-UHFFFAOYSA-N 163627 SR-3459 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 5.3e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163627 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163627&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094789 310305344 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306657 CCCCNNC(=O)c1ccc(C[N-][N+]#N)cc1 InChI=1S/C12H17N5O/c1-2-3-8-14-16-12(18)11-6-4-10(5-7-11)9-15-17-13/h4-7,14H,2-3,8-9H2,1H3,(H,16,18) NRJRDICLAPALFB-UHFFFAOYSA-N 163627 SR-3459 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.5e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163627 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163627&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094789 310305344 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306658 CCCCNNC(=O)c1ccc(C[N-][N+]#N)cc1 InChI=1S/C12H17N5O/c1-2-3-8-14-16-12(18)11-6-4-10(5-7-11)9-15-17-13/h4-7,14H,2-3,8-9H2,1H3,(H,16,18) NRJRDICLAPALFB-UHFFFAOYSA-N 163627 SR-3459 Histone deacetylase 6 Homo sapiens 1.08e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163627 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2556&target=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163627&enzyme=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search 117094789 310305344 1 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH 5EDU,7ZYU,3PHD,3GV4 Protein deacetylase HDAC6 HDAC6_HUMAN Q9UBN7 O94975 Q6NT75 Q7L3E5 Q96CY0 306659 CCCCNNC(=O)c1ccc(C[N-][N+]#N)cc1 InChI=1S/C12H17N5O/c1-2-3-8-14-16-12(18)11-6-4-10(5-7-11)9-15-17-13/h4-7,14H,2-3,8-9H2,1H3,(H,16,18) NRJRDICLAPALFB-UHFFFAOYSA-N 163627 SR-3459 Histone deacetylase 8 Homo sapiens 8.9e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163627 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1996&target=Histone+deacetylase+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163627&enzyme=Histone+deacetylase+8&column=ki&startPg=0&Increment=50&submit=Search 117094789 310305344 1 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 3SFH,3SFF,6ODC,6ODB,6ODA,5FCW,1W22,1VKG,1T69,1T67,1T64,3RQD,3MZ3,3F0R,3F07,5VI6 Histone deacetylase 8 HDAC8_HUMAN Q9BY41 A6ND12 A6ND61 A6NET3 A6NJR3 A8MQ62 B4DKN0 B4DV22 Q86VC8 Q9NP76 Q9NYH4 306660 CCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C10H13BrN2O/c1-2-7-12-13-10(14)8-3-5-9(11)6-4-8/h3-6,12H,2,7H2,1H3,(H,13,14) OTHBGAGRQLSYFV-UHFFFAOYSA-N 163628 SR-3212::US10807944, Compound RLS2-137::US11731934, Compound RLS2-137 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.70e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163628 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163628&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306437 310305345 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306661 CCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C10H13BrN2O/c1-2-7-12-13-10(14)8-3-5-9(11)6-4-8/h3-6,12H,2,7H2,1H3,(H,13,14) OTHBGAGRQLSYFV-UHFFFAOYSA-N 163628 SR-3212::US10807944, Compound RLS2-137::US11731934, Compound RLS2-137 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 3.88e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163628 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163628&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306437 310305345 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306662 CCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C10H13BrN2O/c1-2-7-12-13-10(14)8-3-5-9(11)6-4-8/h3-6,12H,2,7H2,1H3,(H,13,14) OTHBGAGRQLSYFV-UHFFFAOYSA-N 163628 SR-3212::US10807944, Compound RLS2-137::US11731934, Compound RLS2-137 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 2.2e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163628 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163628&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306437 310305345 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306663 CCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C10H13BrN2O/c1-2-7-12-13-10(14)8-3-5-9(11)6-4-8/h3-6,12H,2,7H2,1H3,(H,13,14) OTHBGAGRQLSYFV-UHFFFAOYSA-N 163628 SR-3212::US10807944, Compound RLS2-137::US11731934, Compound RLS2-137 Histone deacetylase 6 Homo sapiens 4.63e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163628 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2556&target=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163628&enzyme=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search 71306437 310305345 1 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH 5EDU,7ZYU,3PHD,3GV4 Protein deacetylase HDAC6 HDAC6_HUMAN Q9UBN7 O94975 Q6NT75 Q7L3E5 Q96CY0 306664 CCCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C12H17BrN2O/c1-2-3-4-9-14-15-12(16)10-5-7-11(13)8-6-10/h5-8,14H,2-4,9H2,1H3,(H,15,16) FSOILGKPVXNZLM-UHFFFAOYSA-N 163629 SR-3970 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.87e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163629 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163629&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094790 310305346 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306665 CCCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C12H17BrN2O/c1-2-3-4-9-14-15-12(16)10-5-7-11(13)8-6-10/h5-8,14H,2-4,9H2,1H3,(H,15,16) FSOILGKPVXNZLM-UHFFFAOYSA-N 163629 SR-3970 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.92e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163629 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163629&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094790 310305346 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306666 CCCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C12H17BrN2O/c1-2-3-4-9-14-15-12(16)10-5-7-11(13)8-6-10/h5-8,14H,2-4,9H2,1H3,(H,15,16) FSOILGKPVXNZLM-UHFFFAOYSA-N 163629 SR-3970 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 9.2e+2 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163629 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163629&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094790 310305346 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306667 CCCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C12H17BrN2O/c1-2-3-4-9-14-15-12(16)10-5-7-11(13)8-6-10/h5-8,14H,2-4,9H2,1H3,(H,15,16) FSOILGKPVXNZLM-UHFFFAOYSA-N 163629 SR-3970 Histone deacetylase 6 Homo sapiens 5.73e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163629 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2556&target=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163629&enzyme=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search 117094790 310305346 1 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH 5EDU,7ZYU,3PHD,3GV4 Protein deacetylase HDAC6 HDAC6_HUMAN Q9UBN7 O94975 Q6NT75 Q7L3E5 Q96CY0 306668 CCCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C12H17BrN2O/c1-2-3-4-9-14-15-12(16)10-5-7-11(13)8-6-10/h5-8,14H,2-4,9H2,1H3,(H,15,16) FSOILGKPVXNZLM-UHFFFAOYSA-N 163629 SR-3970 Histone deacetylase 8 Homo sapiens 4.87e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163629 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1996&target=Histone+deacetylase+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163629&enzyme=Histone+deacetylase+8&column=ki&startPg=0&Increment=50&submit=Search 117094790 310305346 1 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 3SFH,3SFF,6ODC,6ODB,6ODA,5FCW,1W22,1VKG,1T69,1T67,1T64,3RQD,3MZ3,3F0R,3F07,5VI6 Histone deacetylase 8 HDAC8_HUMAN Q9BY41 A6ND12 A6ND61 A6NET3 A6NJR3 A8MQ62 B4DKN0 B4DV22 Q86VC8 Q9NP76 Q9NYH4 306669 CCCCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C13H19BrN2O/c1-2-3-4-5-10-15-16-13(17)11-6-8-12(14)9-7-11/h6-9,15H,2-5,10H2,1H3,(H,16,17) YQIPSZXUSOVGKH-UHFFFAOYSA-N 163630 SR-3367::US10807944, Compound RLS2-284::US11731934, Compound RLS2-284 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.027e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163630 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163630&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094791 310305347 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306670 CCCCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C13H19BrN2O/c1-2-3-4-5-10-15-16-13(17)11-6-8-12(14)9-7-11/h6-9,15H,2-5,10H2,1H3,(H,16,17) YQIPSZXUSOVGKH-UHFFFAOYSA-N 163630 SR-3367::US10807944, Compound RLS2-284::US11731934, Compound RLS2-284 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.611e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163630 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163630&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094791 310305347 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306671 CCCCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C13H19BrN2O/c1-2-3-4-5-10-15-16-13(17)11-6-8-12(14)9-7-11/h6-9,15H,2-5,10H2,1H3,(H,16,17) YQIPSZXUSOVGKH-UHFFFAOYSA-N 163630 SR-3367::US10807944, Compound RLS2-284::US11731934, Compound RLS2-284 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 2.004e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163630 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163630&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094791 310305347 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306672 CCCCCCNNC(=O)c1ccc(Br)cc1 InChI=1S/C13H19BrN2O/c1-2-3-4-5-10-15-16-13(17)11-6-8-12(14)9-7-11/h6-9,15H,2-5,10H2,1H3,(H,16,17) YQIPSZXUSOVGKH-UHFFFAOYSA-N 163630 SR-3367::US10807944, Compound RLS2-284::US11731934, Compound RLS2-284 Histone deacetylase 6 Homo sapiens 3.91e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163630 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2556&target=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163630&enzyme=Histone+deacetylase+6&column=ki&startPg=0&Increment=50&submit=Search 117094791 310305347 1 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH 5EDU,7ZYU,3PHD,3GV4 Protein deacetylase HDAC6 HDAC6_HUMAN Q9UBN7 O94975 Q6NT75 Q7L3E5 Q96CY0 306673 Brc1ccc(cc1)C(=O)NNCCc1ccccc1 InChI=1S/C15H15BrN2O/c16-14-8-6-13(7-9-14)15(19)18-17-11-10-12-4-2-1-3-5-12/h1-9,17H,10-11H2,(H,18,19) PHEVVCRULNVOLA-UHFFFAOYSA-N 163631 SR-3213::US10807944, Compound RLS2-138::US11731934, Compound RLS2-138 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens >5.0e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163631 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163631&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306439 310305348 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306674 Brc1ccc(cc1)C(=O)NNCCc1ccccc1 InChI=1S/C15H15BrN2O/c16-14-8-6-13(7-9-14)15(19)18-17-11-10-12-4-2-1-3-5-12/h1-9,17H,10-11H2,(H,18,19) PHEVVCRULNVOLA-UHFFFAOYSA-N 163631 SR-3213::US10807944, Compound RLS2-138::US11731934, Compound RLS2-138 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens >5.0e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163631 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163631&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306439 310305348 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306675 Brc1ccc(cc1)C(=O)NNCCc1ccccc1 InChI=1S/C15H15BrN2O/c16-14-8-6-13(7-9-14)15(19)18-17-11-10-12-4-2-1-3-5-12/h1-9,17H,10-11H2,(H,18,19) PHEVVCRULNVOLA-UHFFFAOYSA-N 163631 SR-3213::US10807944, Compound RLS2-138::US11731934, Compound RLS2-138 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 2.418e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163631 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163631&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 71306439 310305348 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306676 Brc1ccc(cc1)C(=O)NNCCC1CCCC1 InChI=1S/C14H19BrN2O/c15-13-7-5-12(6-8-13)14(18)17-16-10-9-11-3-1-2-4-11/h5-8,11,16H,1-4,9-10H2,(H,17,18) ZLEUBTRYAAACNU-UHFFFAOYSA-N 163632 SR-3297::US10807944, Compound RLS2-219::US11731934, Compound RLS2-219 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 7.40e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163632 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163632&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094792 310305349 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306677 Brc1ccc(cc1)C(=O)NNCCC1CCCC1 InChI=1S/C14H19BrN2O/c15-13-7-5-12(6-8-13)14(18)17-16-10-9-11-3-1-2-4-11/h5-8,11,16H,1-4,9-10H2,(H,17,18) ZLEUBTRYAAACNU-UHFFFAOYSA-N 163632 SR-3297::US10807944, Compound RLS2-219::US11731934, Compound RLS2-219 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 7.65e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163632 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163632&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094792 310305349 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306678 Brc1ccc(cc1)C(=O)NNCCC1CCCC1 InChI=1S/C14H19BrN2O/c15-13-7-5-12(6-8-13)14(18)17-16-10-9-11-3-1-2-4-11/h5-8,11,16H,1-4,9-10H2,(H,17,18) ZLEUBTRYAAACNU-UHFFFAOYSA-N 163632 SR-3297::US10807944, Compound RLS2-219::US11731934, Compound RLS2-219 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.08e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163632 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163632&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094792 310305349 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306679 Brc1ccc(cc1)C(=O)NNCC1CCCC1 InChI=1S/C13H17BrN2O/c14-12-7-5-11(6-8-12)13(17)16-15-9-10-3-1-2-4-10/h5-8,10,15H,1-4,9H2,(H,16,17) BXLUNIKKCWQZBO-UHFFFAOYSA-N 163633 SR-3364::US10807944, Compound RLS2-256::US11731934, Compound RLS2-256 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 8.81e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163633 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163633&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094793 310305350 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306680 Brc1ccc(cc1)C(=O)NNCC1CCCC1 InChI=1S/C13H17BrN2O/c14-12-7-5-11(6-8-12)13(17)16-15-9-10-3-1-2-4-10/h5-8,10,15H,1-4,9H2,(H,16,17) BXLUNIKKCWQZBO-UHFFFAOYSA-N 163633 SR-3364::US10807944, Compound RLS2-256::US11731934, Compound RLS2-256 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 2.845e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163633 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163633&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094793 310305350 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306681 Brc1ccc(cc1)C(=O)NNCC1CCCC1 InChI=1S/C13H17BrN2O/c14-12-7-5-11(6-8-12)13(17)16-15-9-10-3-1-2-4-10/h5-8,10,15H,1-4,9H2,(H,16,17) BXLUNIKKCWQZBO-UHFFFAOYSA-N 163633 SR-3364::US10807944, Compound RLS2-256::US11731934, Compound RLS2-256 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 6.98e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163633 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163633&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094793 310305350 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306682 Brc1ccc(cc1)C(=O)NNCCCC1CCCC1 InChI=1S/C15H21BrN2O/c16-14-9-7-13(8-10-14)15(19)18-17-11-3-6-12-4-1-2-5-12/h7-10,12,17H,1-6,11H2,(H,18,19) SYMKTBFFFIYEDY-UHFFFAOYSA-N 163634 SR-3365::US10807944, Compound RLS2-257::US11731934, Compound RLS2-257 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens >5.0e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163634 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163634&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094794 310305351 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306683 Brc1ccc(cc1)C(=O)NNCCCC1CCCC1 InChI=1S/C15H21BrN2O/c16-14-9-7-13(8-10-14)15(19)18-17-11-3-6-12-4-1-2-5-12/h7-10,12,17H,1-6,11H2,(H,18,19) SYMKTBFFFIYEDY-UHFFFAOYSA-N 163634 SR-3365::US10807944, Compound RLS2-257::US11731934, Compound RLS2-257 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens >5.0e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163634 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163634&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094794 310305351 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306684 Brc1ccc(cc1)C(=O)NNCCCC1CCCC1 InChI=1S/C15H21BrN2O/c16-14-9-7-13(8-10-14)15(19)18-17-11-3-6-12-4-1-2-5-12/h7-10,12,17H,1-6,11H2,(H,18,19) SYMKTBFFFIYEDY-UHFFFAOYSA-N 163634 SR-3365::US10807944, Compound RLS2-257::US11731934, Compound RLS2-257 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens >5.0e+4 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163634 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163634&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094794 310305351 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306685 CN(C)c1ccc(cc1)C(=O)NNCC1CCCC1 InChI=1S/C15H23N3O/c1-18(2)14-9-7-13(8-10-14)15(19)17-16-11-12-5-3-4-6-12/h7-10,12,16H,3-6,11H2,1-2H3,(H,17,19) LJBJHPWKSLDVNC-UHFFFAOYSA-N 163635 SR-3298::US10807944, Compound RLS2-225::US11731934, Compound RLS2-225 Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.76e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163635 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001091&target=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163635&enzyme=Histone+deacetylase+1%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094795 310305352 2 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 8VRT,8VPQ,8VOJ,7AOA,7AO9,7AO8,6Z2K,6Z2J,4BKX,5ICN,3MAX Histone deacetylase 1 HDAC1_HUMAN Q13547 Q92534 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306686 CN(C)c1ccc(cc1)C(=O)NNCC1CCCC1 InChI=1S/C15H23N3O/c1-18(2)14-9-7-13(8-10-14)15(19)17-16-11-12-5-3-4-6-12/h7-10,12,16H,3-6,11H2,1-2H3,(H,17,19) LJBJHPWKSLDVNC-UHFFFAOYSA-N 163635 SR-3298::US10807944, Compound RLS2-225::US11731934, Compound RLS2-225 Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Homo sapiens 3.25e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163635 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001092&target=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163635&enzyme=Histone+deacetylase+2%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094795 310305352 2 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP 9I2C,9GGN,9GGM,9GGL,8C60,8BPC,8BPB,8BPA,8A0B,7ZZW,7ZZU,7ZZT,7ZZS,7ZZR,7ZZP,7ZZO,9DTQ,6WI3,6WHZ,6WHQ,6WHO,6WHN,7MOZ,7MOY,7MOX,7MOT,7MOS,7LTL,7LTK,7LTG,7KBG,7JS8,6XEC,6XEB,6XDM,6WBZ,6WBW,7KBH,6G3O,4LY1,4LXZ,5IX0,5IWG Histone deacetylase 2 HDAC2_HUMAN Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0 306687 CN(C)c1ccc(cc1)C(=O)NNCC1CCCC1 InChI=1S/C15H23N3O/c1-18(2)14-9-7-13(8-10-14)15(19)17-16-11-12-5-3-4-6-12/h7-10,12,16H,3-6,11H2,1-2H3,(H,17,19) LJBJHPWKSLDVNC-UHFFFAOYSA-N 163635 SR-3298::US10807944, Compound RLS2-225::US11731934, Compound RLS2-225 Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] Homo sapiens 1.67e+3 Curated from the literature by BindingDB 10.1016/j.chembiol.2014.12.015 10.7270/Q2TX3D48 25699604 aid1801336 Wang, Y; Stowe, RL; Pinello, CE; Tian, G; Madoux, F; Li, D; Zhao, LY; Li, JL; Wang, Y; Wang, Y; Ma, H; Hodder, P; Roush, WR; Liao, D 2/19/2015 2/10/2016 University of Florida College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=163635 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001093&target=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=163635&enzyme=Histone+deacetylase+3%2FNuclear+receptor+corepressor+2+%5B395-498%5D&column=ki&startPg=0&Increment=50&submit=Search 117094795 310305352 2 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI 4A69 Histone deacetylase 3 HDAC3_HUMAN O15379 D3DQE1 O43268 Q9UEI5 Q9UEV0 IPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQ 4A69 Nuclear receptor corepressor 2 NCOR2_HUMAN Q9Y618 O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0