BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 51603238 COc1cccc(C#CC2(OC)CCN(Cc3cnc(NC(C)=O)s3)CC2)n1 InChI=1S/C20H24N4O3S/c1-15(25)22-19-21-13-17(28-19)14-24-11-9-20(27-3,10-12-24)8-7-16-5-4-6-18(23-16)26-2/h4-6,13H,9-12,14H2,1-3H3,(H,21,22,25) NEQINUMVNQRSCT-UHFFFAOYSA-N 50645979 CHEMBL5589641 Protein O-GlcNAcase Human 67 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645979 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645979&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377614 519661381 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603239 CCOC1(C#Cc2cccc(OC)n2)CCN(Cc2cnc(NC(C)=O)s2)CC1 InChI=1S/C21H26N4O3S/c1-4-28-21(9-8-17-6-5-7-19(24-17)27-3)10-12-25(13-11-21)15-18-14-22-20(29-18)23-16(2)26/h5-7,14H,4,10-13,15H2,1-3H3,(H,22,23,26) UXFJUQWEPMNKJE-UHFFFAOYSA-N 50645980 CHEMBL5593036 Protein O-GlcNAcase Human 521 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645980 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645980&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377615 519661382 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603240 CCCOC1(C#Cc2cccc(OC)n2)CCN(Cc2cnc(NC(C)=O)s2)CC1 InChI=1S/C22H28N4O3S/c1-4-14-29-22(9-8-18-6-5-7-20(25-18)28-3)10-12-26(13-11-22)16-19-15-23-21(30-19)24-17(2)27/h5-7,15H,4,10-14,16H2,1-3H3,(H,23,24,27) SXYVYXCZSNNKSK-UHFFFAOYSA-N 50645981 CHEMBL5596013 Protein O-GlcNAcase Human 183 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645981 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645981&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177311787 519661383 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603241 COc1cccc(C#CC2(OCc3ccccc3)CCN(Cc3cnc(NC(C)=O)s3)CC2)n1 InChI=1S/C26H28N4O3S/c1-20(31)28-25-27-17-23(34-25)18-30-15-13-26(14-16-30,33-19-21-7-4-3-5-8-21)12-11-22-9-6-10-24(29-22)32-2/h3-10,17H,13-16,18-19H2,1-2H3,(H,27,28,31) PMSVNLJBHGPRHZ-UHFFFAOYSA-N 50645982 CHEMBL5590852 Protein O-GlcNAcase Human 4610 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645982 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645982&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377616 519661384 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603242 COc1cccc(C#CC2(F)CCN(Cc3cnc(NC(C)=O)s3)CC2)n1 InChI=1S/C19H21FN4O2S/c1-14(25)22-18-21-12-16(27-18)13-24-10-8-19(20,9-11-24)7-6-15-4-3-5-17(23-15)26-2/h3-5,12H,8-11,13H2,1-2H3,(H,21,22,25) FKRXQFNLYFYHNU-UHFFFAOYSA-N 50645983 CHEMBL5593571 Protein O-GlcNAcase Human 190 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645983 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645983&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377617 519661385 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603243 COc1cccc(C#CC2(O)CCN(Cc3cnc(NC(C)=O)s3)CC2)n1 InChI=1S/C19H22N4O3S/c1-14(24)21-18-20-12-16(27-18)13-23-10-8-19(25,9-11-23)7-6-15-4-3-5-17(22-15)26-2/h3-5,12,25H,8-11,13H2,1-2H3,(H,20,21,24) MGDGWCXCTALAFJ-UHFFFAOYSA-N 50645984 CHEMBL5593440 Protein O-GlcNAcase Human 1183 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645984 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645984&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377618 519661386 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603244 COc1cccc(C#CC2CCN(Cc3cnc(NC(C)=O)s3)CC2)n1 InChI=1S/C19H22N4O2S/c1-14(24)21-19-20-12-17(26-19)13-23-10-8-15(9-11-23)6-7-16-4-3-5-18(22-16)25-2/h3-5,12,15H,8-11,13H2,1-2H3,(H,20,21,24) GOCYYCTUVVMYNM-UHFFFAOYSA-N 50645985 CHEMBL5593028 Protein O-GlcNAcase Human 23 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645985 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645985&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377619 519661387 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603245 CC(=O)Nc1ncc(CN2CCC(C#Cc3cccc(C)n3)CC2)s1 InChI=1S/C19H22N4OS/c1-14-4-3-5-17(21-14)7-6-16-8-10-23(11-9-16)13-18-12-20-19(25-18)22-15(2)24/h3-5,12,16H,8-11,13H2,1-2H3,(H,20,22,24) VVWNSTZBBAHWFV-UHFFFAOYSA-N 50645986 CHEMBL5594264 Protein O-GlcNAcase Human 43 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645986 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645986&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377620 519661388 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603246 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc(C)cc(C)n3)CC2)s1 InChI=1S/C20H24N4OS/c1-14-10-15(2)22-18(11-14)5-4-17-6-8-24(9-7-17)13-19-12-21-20(26-19)23-16(3)25/h10-12,17H,6-9,13H2,1-3H3,(H,21,23,25) PUJQCLATZBPGFR-UHFFFAOYSA-N 50645987 CHEMBL5583946 Protein O-GlcNAcase Human 5.4 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645987 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645987&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377621 519661389 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603247 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc(C)nc3C)CC2)s1 InChI=1S/C20H24N4OS/c1-14-4-6-18(15(2)22-14)7-5-17-8-10-24(11-9-17)13-19-12-21-20(26-19)23-16(3)25/h4,6,12,17H,8-11,13H2,1-3H3,(H,21,23,25) NTAXQZBUUBSGAN-UHFFFAOYSA-N 50645988 CHEMBL5591704 Protein O-GlcNAcase Human 4.4 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645988 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645988&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377622 519661390 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603248 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc(C)nc(C)c3)CC2)s1 InChI=1S/C20H24N4OS/c1-14-10-18(11-15(2)22-14)5-4-17-6-8-24(9-7-17)13-19-12-21-20(26-19)23-16(3)25/h10-12,17H,6-9,13H2,1-3H3,(H,21,23,25) CLZLCRCOFBFQOE-UHFFFAOYSA-N 50645989 CHEMBL5592062 Protein O-GlcNAcase Human 63 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645989 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645989&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377623 519661391 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603249 CC(=O)Nc1ncc(CN2CCC(C#Cc3ncccc3F)CC2)s1 InChI=1S/C18H19FN4OS/c1-13(24)22-18-21-11-15(25-18)12-23-9-6-14(7-10-23)4-5-17-16(19)3-2-8-20-17/h2-3,8,11,14H,6-7,9-10,12H2,1H3,(H,21,22,24) PZOVCMBSAJJGNY-UHFFFAOYSA-N 50645990 CHEMBL5592814 Protein O-GlcNAcase Human 19 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645990 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645990&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377624 519661392 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603250 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc(F)ccn3)CC2)s1 InChI=1S/C18H19FN4OS/c1-13(24)22-18-21-11-17(25-18)12-23-8-5-14(6-9-23)2-3-16-10-15(19)4-7-20-16/h4,7,10-11,14H,5-6,8-9,12H2,1H3,(H,21,22,24) QVMHDDDXLDQCHT-UHFFFAOYSA-N 50645991 CHEMBL5592377 Protein O-GlcNAcase Human 69 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645991 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645991&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377625 519661393 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603251 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc(F)cn3)CC2)s1 InChI=1S/C18H19FN4OS/c1-13(24)22-18-21-11-17(25-18)12-23-8-6-14(7-9-23)2-4-16-5-3-15(19)10-20-16/h3,5,10-11,14H,6-9,12H2,1H3,(H,21,22,24) ILALHCFKXCMTQP-UHFFFAOYSA-N 50645992 CHEMBL5590741 Protein O-GlcNAcase Human 32 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645992 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645992&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377626 519661394 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603252 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc(N(C)C)nc3)CC2)s1 InChI=1S/C20H25N5OS/c1-15(26)23-20-22-13-18(27-20)14-25-10-8-16(9-11-25)4-5-17-6-7-19(21-12-17)24(2)3/h6-7,12-13,16H,8-11,14H2,1-3H3,(H,22,23,26) QFFUHWPCTGQMPO-UHFFFAOYSA-N 50645993 CHEMBL5579695 Protein O-GlcNAcase Human 3.5 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645993 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645993&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377627 519661395 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603253 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc(N4CCCC4)nc3)CC2)s1 InChI=1S/C22H27N5OS/c1-17(28)25-22-24-15-20(29-22)16-26-12-8-18(9-13-26)4-5-19-6-7-21(23-14-19)27-10-2-3-11-27/h6-7,14-15,18H,2-3,8-13,16H2,1H3,(H,24,25,28) UQEQAEOCVVMOEV-UHFFFAOYSA-N 50645994 CHEMBL5595991 Protein O-GlcNAcase Human 8.8 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645994 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645994&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377628 519661396 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603254 CC(=O)Nc1ncc(CN2CCC(C#Cc3cncc(C)n3)CC2)s1 InChI=1S/C18H21N5OS/c1-13-9-19-10-16(21-13)4-3-15-5-7-23(8-6-15)12-17-11-20-18(25-17)22-14(2)24/h9-11,15H,5-8,12H2,1-2H3,(H,20,22,24) MZGQVPHOULMDNH-UHFFFAOYSA-N 50645995 CHEMBL5591664 Protein O-GlcNAcase Human 51 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645995 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645995&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377629 519661397 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603255 COc1ccc(C#CC2CCN(Cc3cnc(NC(C)=O)s3)CC2)nn1 InChI=1S/C18H21N5O2S/c1-13(24)20-18-19-11-16(26-18)12-23-9-7-14(8-10-23)3-4-15-5-6-17(25-2)22-21-15/h5-6,11,14H,7-10,12H2,1-2H3,(H,19,20,24) ACBCRVQIGWGDMS-UHFFFAOYSA-N 50645996 CHEMBL5584000 Protein O-GlcNAcase Human 34 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645996 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645996&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377630 519661398 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603256 CC(=O)Nc1ncc(CN2CCC(C#Cc3nccc(C)n3)CC2)s1 InChI=1S/C18H21N5OS/c1-13-5-8-19-17(21-13)4-3-15-6-9-23(10-7-15)12-16-11-20-18(25-16)22-14(2)24/h5,8,11,15H,6-7,9-10,12H2,1-2H3,(H,20,22,24) ODQXZVQWLXXJAF-UHFFFAOYSA-N 50645997 CHEMBL5596027 Protein O-GlcNAcase Human 54 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645997 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645997&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377631 519661399 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603257 CC(=O)Nc1ncc(CN2CCC(C#Cc3ncc(C)cn3)CC2)s1 InChI=1S/C18H21N5OS/c1-13-9-19-17(20-10-13)4-3-15-5-7-23(8-6-15)12-16-11-21-18(25-16)22-14(2)24/h9-11,15H,5-8,12H2,1-2H3,(H,21,22,24) TTXNJSUWFWMPHR-UHFFFAOYSA-N 50645998 CHEMBL5594901 Protein O-GlcNAcase Human 57 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645998 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645998&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377632 519661400 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603258 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc(C)ncn3)CC2)s1 InChI=1S/C18H21N5OS/c1-13-9-16(21-12-20-13)4-3-15-5-7-23(8-6-15)11-17-10-19-18(25-17)22-14(2)24/h9-10,12,15H,5-8,11H2,1-2H3,(H,19,22,24) WOQCJQHTWFXKRU-UHFFFAOYSA-N 50645999 CHEMBL5594381 Protein O-GlcNAcase Human 42 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645999 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645999&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377633 519661401 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603259 CC(=O)Nc1ncc(CN2CCC(C#Cc3cnc(C)nc3)CC2)s1 InChI=1S/C18H21N5OS/c1-13-19-9-16(10-20-13)4-3-15-5-7-23(8-6-15)12-17-11-21-18(25-17)22-14(2)24/h9-11,15H,5-8,12H2,1-2H3,(H,21,22,24) IBQCYHLSHJYSLG-UHFFFAOYSA-N 50646000 CHEMBL5590996 Protein O-GlcNAcase Human 42 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646000 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646000&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377634 519661402 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603260 COc1cnc(C#CC2CCN(Cc3cnc(NC(C)=O)s3)CC2)nc1 InChI=1S/C18H21N5O2S/c1-13(24)22-18-21-11-16(26-18)12-23-7-5-14(6-8-23)3-4-17-19-9-15(25-2)10-20-17/h9-11,14H,5-8,12H2,1-2H3,(H,21,22,24) UMACQEUWBPFQSZ-UHFFFAOYSA-N 50646001 CHEMBL5583610 Protein O-GlcNAcase Human 52 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646001 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646001&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377635 519661403 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603261 COc1ncc(C#CC2CCN(Cc3cnc(NC(C)=O)s3)CC2)cn1 InChI=1S/C18H21N5O2S/c1-13(24)22-18-21-11-16(26-18)12-23-7-5-14(6-8-23)3-4-15-9-19-17(25-2)20-10-15/h9-11,14H,5-8,12H2,1-2H3,(H,21,22,24) ZSINBCSGIUCGCZ-UHFFFAOYSA-N 50646002 CHEMBL5590598 Protein O-GlcNAcase Human 110 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646002 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646002&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377636 519661404 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603262 COc1ncncc1C#CC1CCN(Cc2cnc(NC(C)=O)s2)CC1 InChI=1S/C18H21N5O2S/c1-13(24)22-18-20-10-16(26-18)11-23-7-5-14(6-8-23)3-4-15-9-19-12-21-17(15)25-2/h9-10,12,14H,5-8,11H2,1-2H3,(H,20,22,24) CYWXVYUHUJXAQE-UHFFFAOYSA-N 50646003 CHEMBL5593786 Protein O-GlcNAcase Human 43 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646003 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646003&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377637 519661405 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603263 CC(=O)Nc1ncc(CN2CCC(C#Cc3cnc(OC(C)C)nc3)CC2)s1 InChI=1S/C20H25N5O2S/c1-14(2)27-19-21-10-17(11-22-19)5-4-16-6-8-25(9-7-16)13-18-12-23-20(28-18)24-15(3)26/h10-12,14,16H,6-9,13H2,1-3H3,(H,23,24,26) VUJPFYQQOBGWFC-UHFFFAOYSA-N 50646004 CHEMBL5594139 Protein O-GlcNAcase Human 11 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646004 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646004&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377638 519661406 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603264 CC(=O)Nc1ncc(CN2CCC(C#Cc3cnc(N(C)C)nc3)CC2)s1 InChI=1S/C19H24N6OS/c1-14(26)23-19-22-12-17(27-19)13-25-8-6-15(7-9-25)4-5-16-10-20-18(21-11-16)24(2)3/h10-12,15H,6-9,13H2,1-3H3,(H,22,23,26) NWGNKQREQAFWEV-UHFFFAOYSA-N 50646005 CHEMBL5591695 Protein O-GlcNAcase Human 0.430000 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646005 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646005&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377639 519661407 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603265 CC(=O)Nc1ncc(CN2CCC(C#Cc3cnc(N4CCCC4)nc3)CC2)s1 InChI=1S/C21H26N6OS/c1-16(28)25-21-24-14-19(29-21)15-26-10-6-17(7-11-26)4-5-18-12-22-20(23-13-18)27-8-2-3-9-27/h12-14,17H,2-3,6-11,15H2,1H3,(H,24,25,28) MDFATNIUMQLSSF-UHFFFAOYSA-N 50646006 CHEMBL5591089 Protein O-GlcNAcase Human 3.8 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646006 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646006&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377640 519661408 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603266 CC(=O)Nc1ncc(CN2CCC(C#Cc3nccc(C(F)(F)F)n3)CC2)s1 InChI=1S/C18H18F3N5OS/c1-12(27)24-17-23-10-14(28-17)11-26-8-5-13(6-9-26)2-3-16-22-7-4-15(25-16)18(19,20)21/h4,7,10,13H,5-6,8-9,11H2,1H3,(H,23,24,27) OMPSHOFMJAKGRL-UHFFFAOYSA-N 50646007 CHEMBL5591556 Protein O-GlcNAcase Human 33 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646007 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646007&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377641 519661409 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603267 CC(=O)Nc1ncc(CN2CCC(C#Cc3ncc(C(F)(F)F)cn3)CC2)s1 InChI=1S/C18H18F3N5OS/c1-12(27)25-17-24-10-15(28-17)11-26-6-4-13(5-7-26)2-3-16-22-8-14(9-23-16)18(19,20)21/h8-10,13H,4-7,11H2,1H3,(H,24,25,27) VUBSUHOSYGKROL-UHFFFAOYSA-N 50646008 CHEMBL5591919 Protein O-GlcNAcase Human 24 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646008 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646008&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377642 519661410 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603268 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc(C(F)(F)F)ncn3)CC2)s1 InChI=1S/C18H18F3N5OS/c1-12(27)25-17-22-9-15(28-17)10-26-6-4-13(5-7-26)2-3-14-8-16(18(19,20)21)24-11-23-14/h8-9,11,13H,4-7,10H2,1H3,(H,22,25,27) XDLSFSNDUXVTGV-UHFFFAOYSA-N 50646009 CHEMBL5592385 Protein O-GlcNAcase Human 3.6 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646009 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646009&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377643 519661411 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603269 CC(=O)Nc1ncc(CN2CCC(C#Cc3cnc(C(F)(F)F)nc3)CC2)s1 InChI=1S/C18H18F3N5OS/c1-12(27)25-17-24-10-15(28-17)11-26-6-4-13(5-7-26)2-3-14-8-22-16(23-9-14)18(19,20)21/h8-10,13H,4-7,11H2,1H3,(H,24,25,27) IXYFAZUDXPERCX-UHFFFAOYSA-N 50646010 CHEMBL5591460 Protein O-GlcNAcase Human 8.7 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646010 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646010&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377644 519661412 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603270 CC(=O)Nc1ncc(CN2CCC(C#Cc3cncnc3C(F)(F)F)CC2)s1 InChI=1S/C18H18F3N5OS/c1-12(27)25-17-23-9-15(28-17)10-26-6-4-13(5-7-26)2-3-14-8-22-11-24-16(14)18(19,20)21/h8-9,11,13H,4-7,10H2,1H3,(H,23,25,27) JVMLYBDKIUIWME-UHFFFAOYSA-N 50646011 CHEMBL5595460 Protein O-GlcNAcase Human 123 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646011 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646011&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377645 519661413 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603271 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4ccccc4n3)CC2)s1 InChI=1S/C22H22N4OS/c1-16(27)24-22-23-14-20(28-22)15-26-12-10-17(11-13-26)6-8-19-9-7-18-4-2-3-5-21(18)25-19/h2-5,7,9,14,17H,10-13,15H2,1H3,(H,23,24,27) JTFRPPPJKJBILB-UHFFFAOYSA-N 50646012 CHEMBL5591950 Protein O-GlcNAcase Human 10 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646012 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646012&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377646 519661414 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603272 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4nc(C)ccc4c3)CC2)s1 InChI=1S/C23H24N4OS/c1-16-3-7-20-13-19(6-8-22(20)25-16)5-4-18-9-11-27(12-10-18)15-21-14-24-23(29-21)26-17(2)28/h3,6-8,13-14,18H,9-12,15H2,1-2H3,(H,24,26,28) JQOLSWAGLVTNCF-UHFFFAOYSA-N 50646013 CHEMBL5583633 Protein O-GlcNAcase Human 57 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646013 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646013&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377647 519661415 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603273 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc4cccnc4cc3C)CC2)s1 InChI=1S/C23H24N4OS/c1-16-12-22-20(4-3-9-24-22)13-19(16)6-5-18-7-10-27(11-8-18)15-21-14-25-23(29-21)26-17(2)28/h3-4,9,12-14,18H,7-8,10-11,15H2,1-2H3,(H,25,26,28) QFOHIRQSSZIYJP-UHFFFAOYSA-N 50646014 CHEMBL5591879 Protein O-GlcNAcase Human 1.5 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646014 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646014&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377648 519661416 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603274 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc(C)c4ncccc4c3)CC2)s1 InChI=1S/C23H24N4OS/c1-16-12-19(13-20-4-3-9-24-22(16)20)6-5-18-7-10-27(11-8-18)15-21-14-25-23(29-21)26-17(2)28/h3-4,9,12-14,18H,7-8,10-11,15H2,1-2H3,(H,25,26,28) XDPJQIOLCUHNOH-UHFFFAOYSA-N 50646015 CHEMBL5593700 Protein O-GlcNAcase Human 0.720000 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646015 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646015&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377649 519661417 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603275 CC(=O)Nc1ncc(CN2CCC(C#Cc3cccc4ccoc34)CC2)s1 InChI=1S/C21H21N3O2S/c1-15(25)23-21-22-13-19(27-21)14-24-10-7-16(8-11-24)5-6-17-3-2-4-18-9-12-26-20(17)18/h2-4,9,12-13,16H,7-8,10-11,14H2,1H3,(H,22,23,25) VRXPXULVQVKAPX-UHFFFAOYSA-N 50646016 CHEMBL5594221 Protein O-GlcNAcase Human 1.8 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646016 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646016&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377650 519661418 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603276 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4occc4c3)CC2)s1 InChI=1S/C21H21N3O2S/c1-15(25)23-21-22-13-19(27-21)14-24-9-6-16(7-10-24)2-3-17-4-5-20-18(12-17)8-11-26-20/h4-5,8,11-13,16H,6-7,9-10,14H2,1H3,(H,22,23,25) SSQLQKZAKWUAOO-UHFFFAOYSA-N 50646017 CHEMBL5595937 Protein O-GlcNAcase Human 16 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646017 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646017&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377651 519661419 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603277 CC(=O)Nc1ncc(CN2CCC(C#Cc3cccc4ccsc34)CC2)s1 InChI=1S/C21H21N3OS2/c1-15(25)23-21-22-13-19(27-21)14-24-10-7-16(8-11-24)5-6-17-3-2-4-18-9-12-26-20(17)18/h2-4,9,12-13,16H,7-8,10-11,14H2,1H3,(H,22,23,25) QWQUVGLZCXJJET-UHFFFAOYSA-N 50646018 CHEMBL5591707 Protein O-GlcNAcase Human 112 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646018 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646018&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377652 519661420 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603278 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4sccc4c3)CC2)s1 InChI=1S/C21H21N3OS2/c1-15(25)23-21-22-13-19(27-21)14-24-9-6-16(7-10-24)2-3-17-4-5-20-18(12-17)8-11-26-20/h4-5,8,11-13,16H,6-7,9-10,14H2,1H3,(H,22,23,25) LIEIVVMKSIMZHY-UHFFFAOYSA-N 50646019 CHEMBL5593996 Protein O-GlcNAcase Human 58 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646019 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646019&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377653 519661421 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603279 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4[nH]ccc4c3)CC2)s1 InChI=1S/C21H22N4OS/c1-15(26)24-21-23-13-19(27-21)14-25-10-7-16(8-11-25)2-3-17-4-5-20-18(12-17)6-9-22-20/h4-6,9,12-13,16,22H,7-8,10-11,14H2,1H3,(H,23,24,26) YNGQCPLSGUDXDG-UHFFFAOYSA-N 50646020 CHEMBL5593505 Protein O-GlcNAcase Human 25 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646020 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646020&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377654 519661422 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603280 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccn4ccnc4c3)CC2)s1 InChI=1S/C20H21N5OS/c1-15(26)23-20-22-13-18(27-20)14-24-8-4-16(5-9-24)2-3-17-6-10-25-11-7-21-19(25)12-17/h6-7,10-13,16H,4-5,8-9,14H2,1H3,(H,22,23,26) QRUDZHCSEZNLFD-UHFFFAOYSA-N 50646021 CHEMBL5590863 Protein O-GlcNAcase Human 26 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646021 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646021&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377655 519661423 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603281 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccn4nccc4c3)CC2)s1 InChI=1S/C20H21N5OS/c1-15(26)23-20-21-13-19(27-20)14-24-9-5-16(6-10-24)2-3-17-7-11-25-18(12-17)4-8-22-25/h4,7-8,11-13,16H,5-6,9-10,14H2,1H3,(H,21,23,26) HNGCFCGIQHMUER-UHFFFAOYSA-N 50646022 CHEMBL5591471 Protein O-GlcNAcase Human 49 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646022 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646022&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377656 519661424 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603282 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccn4nccc4n3)CC2)s1 InChI=1S/C19H20N6OS/c1-14(26)22-19-20-12-17(27-19)13-24-9-5-15(6-10-24)2-3-16-7-11-25-18(23-16)4-8-21-25/h4,7-8,11-12,15H,5-6,9-10,13H2,1H3,(H,20,22,26) WAQOCZSFGVCGKT-UHFFFAOYSA-N 50646023 CHEMBL5592284 Protein O-GlcNAcase Human 16 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646023 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646023&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377657 519661425 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603283 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)OCO4)CC2)s1 InChI=1S/C20H21N3O3S/c1-14(24)22-20-21-11-17(27-20)12-23-8-6-15(7-9-23)2-3-16-4-5-18-19(10-16)26-13-25-18/h4-5,10-11,15H,6-9,12-13H2,1H3,(H,21,22,24) AWGRSWKUZOUOMG-UHFFFAOYSA-N 50646024 CHEMBL5590193 Protein O-GlcNAcase Human 9.5 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646024 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646024&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377658 519661426 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603284 CC(=O)Nc1ncc(CN2CCC(C#Cc3cccc4c3OCO4)CC2)s1 InChI=1S/C20H21N3O3S/c1-14(24)22-20-21-11-17(27-20)12-23-9-7-15(8-10-23)5-6-16-3-2-4-18-19(16)26-13-25-18/h2-4,11,15H,7-10,12-13H2,1H3,(H,21,22,24) RCSINPRWNDCHHE-UHFFFAOYSA-N 50646025 CHEMBL5595069 Protein O-GlcNAcase Human 29 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646025 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646025&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377659 519661427 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603285 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)CCO4)CC2)s1 InChI=1S/C21H23N3O2S/c1-15(25)23-21-22-13-19(27-21)14-24-9-6-16(7-10-24)2-3-17-4-5-20-18(12-17)8-11-26-20/h4-5,12-13,16H,6-11,14H2,1H3,(H,22,23,25) KCILMMWOUWBGCK-UHFFFAOYSA-N 50646026 CHEMBL5591200 Protein O-GlcNAcase Human 8.9 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646026 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646026&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377660 519661428 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603286 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)CCC(=O)N4)CC2)s1 InChI=1S/C22H24N4O2S/c1-15(27)24-22-23-13-19(29-22)14-26-10-8-16(9-11-26)2-3-17-4-6-20-18(12-17)5-7-21(28)25-20/h4,6,12-13,16H,5,7-11,14H2,1H3,(H,25,28)(H,23,24,27) CXHLDIMOVQEPNM-UHFFFAOYSA-N 50646027 CHEMBL5591099 Protein O-GlcNAcase Human 8.0 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646027 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646027&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377661 519661429 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603287 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)CCNC4=O)CC2)s1 InChI=1S/C22H24N4O2S/c1-15(27)25-22-24-13-19(29-22)14-26-10-7-16(8-11-26)2-3-17-4-5-20-18(12-17)6-9-23-21(20)28/h4-5,12-13,16H,6-11,14H2,1H3,(H,23,28)(H,24,25,27) ZILCITIYCAVCGP-UHFFFAOYSA-N 50646028 CHEMBL5592529 Protein O-GlcNAcase Human 24 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646028 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646028&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377662 519661430 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603288 CC(=O)Nc1ncc(CN2CCC(C#Cc3cccc4c3CCC(=O)N4)CC2)s1 InChI=1S/C22H24N4O2S/c1-15(27)24-22-23-13-18(29-22)14-26-11-9-16(10-12-26)5-6-17-3-2-4-20-19(17)7-8-21(28)25-20/h2-4,13,16H,7-12,14H2,1H3,(H,25,28)(H,23,24,27) XCFQDTRXSIZFKG-UHFFFAOYSA-N 50646029 CHEMBL5592778 Protein O-GlcNAcase Human 1.7 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646029 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646029&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377663 519661431 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603289 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)NCCC4)CC2)s1 InChI=1S/C22H26N4OS/c1-16(27)25-22-24-14-20(28-22)15-26-11-8-17(9-12-26)4-5-18-6-7-19-3-2-10-23-21(19)13-18/h6-7,13-14,17,23H,2-3,8-12,15H2,1H3,(H,24,25,27) GJVKGOTYFZOFPT-UHFFFAOYSA-N 50646030 CHEMBL5594475 Protein O-GlcNAcase Human 0.850000 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646030 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646030&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377664 519661432 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603290 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)CNCC4)CC2)s1 InChI=1S/C22H26N4OS/c1-16(27)25-22-24-14-21(28-22)15-26-10-7-17(8-11-26)2-3-18-4-5-19-6-9-23-13-20(19)12-18/h4-5,12,14,17,23H,6-11,13,15H2,1H3,(H,24,25,27) CLDPUOPOFBMSAH-UHFFFAOYSA-N 50646031 CHEMBL5592188 Protein O-GlcNAcase Human 100 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646031 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646031&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377665 519661433 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603291 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)CCNC4)CC2)s1 InChI=1S/C22H26N4OS/c1-16(27)25-22-24-14-21(28-22)15-26-10-7-17(8-11-26)2-3-18-4-5-20-13-23-9-6-19(20)12-18/h4-5,12,14,17,23H,6-11,13,15H2,1H3,(H,24,25,27) OYCVRJAKRBDSKD-UHFFFAOYSA-N 50646032 CHEMBL5592881 Protein O-GlcNAcase Human 185 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646032 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646032&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377666 519661434 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603292 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)CCCN4)CC2)s1 InChI=1S/C22H26N4OS/c1-16(27)25-22-24-14-20(28-22)15-26-11-8-17(9-12-26)4-5-18-6-7-21-19(13-18)3-2-10-23-21/h6-7,13-14,17,23H,2-3,8-12,15H2,1H3,(H,24,25,27) QBFCYDPGASTWQU-UHFFFAOYSA-N 50646033 CHEMBL5591513 Protein O-GlcNAcase Human 4.9 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646033 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646033&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377667 519661435 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603293 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(n3)CCCN4)CC2)s1 InChI=1S/C21H25N5OS/c1-15(27)24-21-23-13-18(28-21)14-26-11-8-16(9-12-26)4-5-17-6-7-19-20(25-17)3-2-10-22-19/h6-7,13,16,22H,2-3,8-12,14H2,1H3,(H,23,24,27) JFAGLGCDMPPTBY-UHFFFAOYSA-N 50646034 CHEMBL5591551 Protein O-GlcNAcase Human 4.6 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646034 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646034&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377668 519661436 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603294 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc4c(cn3)NCCC4)CC2)s1 InChI=1S/C21H25N5OS/c1-15(27)25-21-24-12-19(28-21)14-26-9-6-16(7-10-26)4-5-18-11-17-3-2-8-22-20(17)13-23-18/h11-13,16,22H,2-3,6-10,14H2,1H3,(H,24,25,27) QJMSJAICRGEYTH-UHFFFAOYSA-N 50646035 CHEMBL5591488 Protein O-GlcNAcase Human 0.340000 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646035 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646035&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377669 519661437 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603295 CC(=O)Nc1ncc(CN2CCC(C#Cc3cnc4c(c3)CCCN4)CC2)s1 InChI=1S/C21H25N5OS/c1-15(27)25-21-24-13-19(28-21)14-26-9-6-16(7-10-26)4-5-17-11-18-3-2-8-22-20(18)23-12-17/h11-13,16H,2-3,6-10,14H2,1H3,(H,22,23)(H,24,25,27) ULSIBXYDGDCUIR-UHFFFAOYSA-N 50646036 CHEMBL5590780 Protein O-GlcNAcase Human 3.0 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646036 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646036&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377670 519661438 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603296 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3F)CCCN4)CC2)s1 InChI=1S/C22H25FN4OS/c1-15(28)26-22-25-13-18(29-22)14-27-11-8-16(9-12-27)4-5-17-6-7-20-19(21(17)23)3-2-10-24-20/h6-7,13,16,24H,2-3,8-12,14H2,1H3,(H,25,26,28) NSCKWOHYPAPDSH-UHFFFAOYSA-N 50646037 CHEMBL5592023 Protein O-GlcNAcase Human 12 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646037 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646037&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377671 519661439 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603297 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc4c(cc3F)NCCC4)CC2)s1 InChI=1S/C22H25FN4OS/c1-15(28)26-22-25-13-19(29-22)14-27-9-6-16(7-10-27)4-5-17-11-18-3-2-8-24-21(18)12-20(17)23/h11-13,16,24H,2-3,6-10,14H2,1H3,(H,25,26,28) WTYLQNGKABAHPT-UHFFFAOYSA-N 50646038 CHEMBL5584048 Protein O-GlcNAcase Human 8.9 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646038 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646038&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377672 519661440 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603298 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc(F)c4c(c3)CCCN4)CC2)s1 InChI=1S/C22H25FN4OS/c1-15(28)26-22-25-13-19(29-22)14-27-9-6-16(7-10-27)4-5-17-11-18-3-2-8-24-21(18)20(23)12-17/h11-13,16,24H,2-3,6-10,14H2,1H3,(H,25,26,28) WQWMVVVYQFNXKX-UHFFFAOYSA-N 50646039 CHEMBL5593511 Protein O-GlcNAcase Human 3.3 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646039 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646039&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377673 519661441 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603299 CC(=O)Nc1nc(F)c(CN2CC[C@H](OCc3nnc(C)o3)C[C@@H]2C)s1 InChI=1S/C16H22FN5O3S/c1-9-6-12(24-8-14-21-20-11(3)25-14)4-5-22(9)7-13-15(17)19-16(26-13)18-10(2)23/h9,12H,4-8H2,1-3H3,(H,18,19,23) OFNRINRWEARWEM-UHFFFAOYSA-N 50646040 CHEMBL5592978 Protein O-GlcNAcase Human 2.1 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646040 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646040&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 135384249 519661442 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603300 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc(C)cc(C)n3)CC2)s1 InChI=1S/C20H24N4OS/c1-14-10-15(2)22-18(11-14)5-4-17-6-8-24(9-7-17)13-19-12-21-20(26-19)23-16(3)25/h10-12,17H,6-9,13H2,1-3H3,(H,21,23,25) PUJQCLATZBPGFR-UHFFFAOYSA-N 50645987 CHEMBL5583946 Protein O-GlcNAcase Rat 97 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645987 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645987&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377621 519661389 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603301 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc(C)nc3C)CC2)s1 InChI=1S/C20H24N4OS/c1-14-4-6-18(15(2)22-14)7-5-17-8-10-24(11-9-17)13-19-12-21-20(26-19)23-16(3)25/h4,6,12,17H,8-11,13H2,1-3H3,(H,21,23,25) NTAXQZBUUBSGAN-UHFFFAOYSA-N 50645988 CHEMBL5591704 Protein O-GlcNAcase Rat 86 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645988 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645988&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377622 519661390 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603302 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc(N4CCCC4)nc3)CC2)s1 InChI=1S/C22H27N5OS/c1-17(28)25-22-24-15-20(29-22)16-26-12-8-18(9-13-26)4-5-19-6-7-21(23-14-19)27-10-2-3-11-27/h6-7,14-15,18H,2-3,8-13,16H2,1H3,(H,24,25,28) UQEQAEOCVVMOEV-UHFFFAOYSA-N 50645994 CHEMBL5595991 Protein O-GlcNAcase Rat 98 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645994 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645994&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377628 519661396 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603303 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc(C)ncn3)CC2)s1 InChI=1S/C18H21N5OS/c1-13-9-16(21-12-20-13)4-3-15-5-7-23(8-6-15)11-17-10-19-18(25-17)22-14(2)24/h9-10,12,15H,5-8,11H2,1-2H3,(H,19,22,24) WOQCJQHTWFXKRU-UHFFFAOYSA-N 50645999 CHEMBL5594381 Protein O-GlcNAcase Rat 205 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645999 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645999&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377633 519661401 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603304 CC(=O)Nc1ncc(CN2CCC(C#Cc3cnc(C)nc3)CC2)s1 InChI=1S/C18H21N5OS/c1-13-19-9-16(10-20-13)4-3-15-5-7-23(8-6-15)12-17-11-21-18(25-17)22-14(2)24/h9-11,15H,5-8,12H2,1-2H3,(H,21,22,24) IBQCYHLSHJYSLG-UHFFFAOYSA-N 50646000 CHEMBL5590996 Protein O-GlcNAcase Rat 90 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646000 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646000&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377634 519661402 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603305 COc1ncc(C#CC2CCN(Cc3cnc(NC(C)=O)s3)CC2)cn1 InChI=1S/C18H21N5O2S/c1-13(24)22-18-21-11-16(26-18)12-23-7-5-14(6-8-23)3-4-15-9-19-17(25-2)20-10-15/h9-11,14H,5-8,12H2,1-2H3,(H,21,22,24) ZSINBCSGIUCGCZ-UHFFFAOYSA-N 50646002 CHEMBL5590598 Protein O-GlcNAcase Rat 49 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646002 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646002&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377636 519661404 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603306 COc1ncncc1C#CC1CCN(Cc2cnc(NC(C)=O)s2)CC1 InChI=1S/C18H21N5O2S/c1-13(24)22-18-20-10-16(26-18)11-23-7-5-14(6-8-23)3-4-15-9-19-12-21-17(15)25-2/h9-10,12,14H,5-8,11H2,1-2H3,(H,20,22,24) CYWXVYUHUJXAQE-UHFFFAOYSA-N 50646003 CHEMBL5593786 Protein O-GlcNAcase Rat 61 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646003 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646003&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377637 519661405 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603307 CC(=O)Nc1ncc(CN2CCC(C#Cc3cnc(OC(C)C)nc3)CC2)s1 InChI=1S/C20H25N5O2S/c1-14(2)27-19-21-10-17(11-22-19)5-4-16-6-8-25(9-7-16)13-18-12-23-20(28-18)24-15(3)26/h10-12,14,16H,6-9,13H2,1-3H3,(H,23,24,26) VUJPFYQQOBGWFC-UHFFFAOYSA-N 50646004 CHEMBL5594139 Protein O-GlcNAcase Rat 21 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646004 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646004&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377638 519661406 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603308 CC(=O)Nc1ncc(CN2CCC(C#Cc3cnc(C(F)(F)F)nc3)CC2)s1 InChI=1S/C18H18F3N5OS/c1-12(27)25-17-24-10-15(28-17)11-26-6-4-13(5-7-26)2-3-14-8-22-16(23-9-14)18(19,20)21/h8-10,13H,4-7,11H2,1H3,(H,24,25,27) IXYFAZUDXPERCX-UHFFFAOYSA-N 50646010 CHEMBL5591460 Protein O-GlcNAcase Rat 91 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646010 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646010&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377644 519661412 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603309 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc4cccnc4cc3C)CC2)s1 InChI=1S/C23H24N4OS/c1-16-12-22-20(4-3-9-24-22)13-19(16)6-5-18-7-10-27(11-8-18)15-21-14-25-23(29-21)26-17(2)28/h3-4,9,12-14,18H,7-8,10-11,15H2,1-2H3,(H,25,26,28) QFOHIRQSSZIYJP-UHFFFAOYSA-N 50646014 CHEMBL5591879 Protein O-GlcNAcase Rat 26 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646014 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646014&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377648 519661416 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603310 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc(C)c4ncccc4c3)CC2)s1 InChI=1S/C23H24N4OS/c1-16-12-19(13-20-4-3-9-24-22(16)20)6-5-18-7-10-27(11-8-18)15-21-14-25-23(29-21)26-17(2)28/h3-4,9,12-14,18H,7-8,10-11,15H2,1-2H3,(H,25,26,28) XDPJQIOLCUHNOH-UHFFFAOYSA-N 50646015 CHEMBL5593700 Protein O-GlcNAcase Rat 52 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646015 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646015&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377649 519661417 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603311 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)OCO4)CC2)s1 InChI=1S/C20H21N3O3S/c1-14(24)22-20-21-11-17(27-20)12-23-8-6-15(7-9-23)2-3-16-4-5-18-19(10-16)26-13-25-18/h4-5,10-11,15H,6-9,12-13H2,1H3,(H,21,22,24) AWGRSWKUZOUOMG-UHFFFAOYSA-N 50646024 CHEMBL5590193 Protein O-GlcNAcase Rat 993 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646024 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646024&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377658 519661426 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603312 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)CCO4)CC2)s1 InChI=1S/C21H23N3O2S/c1-15(25)23-21-22-13-19(27-21)14-24-9-6-16(7-10-24)2-3-17-4-5-20-18(12-17)8-11-26-20/h4-5,12-13,16H,6-11,14H2,1H3,(H,22,23,25) KCILMMWOUWBGCK-UHFFFAOYSA-N 50646026 CHEMBL5591200 Protein O-GlcNAcase Rat 62 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646026 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646026&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377660 519661428 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603313 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)CCC(=O)N4)CC2)s1 InChI=1S/C22H24N4O2S/c1-15(27)24-22-23-13-19(29-22)14-26-10-8-16(9-11-26)2-3-17-4-6-20-18(12-17)5-7-21(28)25-20/h4,6,12-13,16H,5,7-11,14H2,1H3,(H,25,28)(H,23,24,27) CXHLDIMOVQEPNM-UHFFFAOYSA-N 50646027 CHEMBL5591099 Protein O-GlcNAcase Rat 25 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646027 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646027&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377661 519661429 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603314 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)CCNC4=O)CC2)s1 InChI=1S/C22H24N4O2S/c1-15(27)25-22-24-13-19(29-22)14-26-10-7-16(8-11-26)2-3-17-4-5-20-18(12-17)6-9-23-21(20)28/h4-5,12-13,16H,6-11,14H2,1H3,(H,23,28)(H,24,25,27) ZILCITIYCAVCGP-UHFFFAOYSA-N 50646028 CHEMBL5592529 Protein O-GlcNAcase Rat 32 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646028 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646028&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377662 519661430 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603315 CC(=O)Nc1ncc(CN2CCC(C#Cc3cccc4c3CCC(=O)N4)CC2)s1 InChI=1S/C22H24N4O2S/c1-15(27)24-22-23-13-18(29-22)14-26-11-9-16(10-12-26)5-6-17-3-2-4-20-19(17)7-8-21(28)25-20/h2-4,13,16H,7-12,14H2,1H3,(H,25,28)(H,23,24,27) XCFQDTRXSIZFKG-UHFFFAOYSA-N 50646029 CHEMBL5592778 Protein O-GlcNAcase Rat 33 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646029 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646029&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377663 519661431 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603316 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)NCCC4)CC2)s1 InChI=1S/C22H26N4OS/c1-16(27)25-22-24-14-20(28-22)15-26-11-8-17(9-12-26)4-5-18-6-7-19-3-2-10-23-21(19)13-18/h6-7,13-14,17,23H,2-3,8-12,15H2,1H3,(H,24,25,27) GJVKGOTYFZOFPT-UHFFFAOYSA-N 50646030 CHEMBL5594475 Protein O-GlcNAcase Rat 54 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646030 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646030&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377664 519661432 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603317 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3)CCCN4)CC2)s1 InChI=1S/C22H26N4OS/c1-16(27)25-22-24-14-20(28-22)15-26-11-8-17(9-12-26)4-5-18-6-7-21-19(13-18)3-2-10-23-21/h6-7,13-14,17,23H,2-3,8-12,15H2,1H3,(H,24,25,27) QBFCYDPGASTWQU-UHFFFAOYSA-N 50646033 CHEMBL5591513 Protein O-GlcNAcase Rat 7.5 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646033 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646033&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377667 519661435 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603318 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(n3)CCCN4)CC2)s1 InChI=1S/C21H25N5OS/c1-15(27)24-21-23-13-18(28-21)14-26-11-8-16(9-12-26)4-5-17-6-7-19-20(25-17)3-2-10-22-19/h6-7,13,16,22H,2-3,8-12,14H2,1H3,(H,23,24,27) JFAGLGCDMPPTBY-UHFFFAOYSA-N 50646034 CHEMBL5591551 Protein O-GlcNAcase Rat 106 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646034 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646034&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377668 519661436 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603319 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc4c(cn3)NCCC4)CC2)s1 InChI=1S/C21H25N5OS/c1-15(27)25-21-24-12-19(28-21)14-26-9-6-16(7-10-26)4-5-18-11-17-3-2-8-22-20(17)13-23-18/h11-13,16,22H,2-3,6-10,14H2,1H3,(H,24,25,27) QJMSJAICRGEYTH-UHFFFAOYSA-N 50646035 CHEMBL5591488 Protein O-GlcNAcase Rat 28 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646035 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646035&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377669 519661437 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603320 CC(=O)Nc1ncc(CN2CCC(C#Cc3cnc4c(c3)CCCN4)CC2)s1 InChI=1S/C21H25N5OS/c1-15(27)25-21-24-13-19(28-21)14-26-9-6-16(7-10-26)4-5-17-11-18-3-2-8-22-20(18)23-12-17/h11-13,16H,2-3,6-10,14H2,1H3,(H,22,23)(H,24,25,27) ULSIBXYDGDCUIR-UHFFFAOYSA-N 50646036 CHEMBL5590780 Protein O-GlcNAcase Rat 184 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646036 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646036&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377670 519661438 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603321 CC(=O)Nc1ncc(CN2CCC(C#Cc3ccc4c(c3F)CCCN4)CC2)s1 InChI=1S/C22H25FN4OS/c1-15(28)26-22-25-13-18(29-22)14-27-11-8-16(9-12-27)4-5-17-6-7-20-19(21(17)23)3-2-10-24-20/h6-7,13,16,24H,2-3,8-12,14H2,1H3,(H,25,26,28) NSCKWOHYPAPDSH-UHFFFAOYSA-N 50646037 CHEMBL5592023 Protein O-GlcNAcase Rat 11 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646037 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646037&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377671 519661439 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603322 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc4c(cc3F)NCCC4)CC2)s1 InChI=1S/C22H25FN4OS/c1-15(28)26-22-25-13-19(29-22)14-27-9-6-16(7-10-27)4-5-17-11-18-3-2-8-24-21(18)12-20(17)23/h11-13,16,24H,2-3,6-10,14H2,1H3,(H,25,26,28) WTYLQNGKABAHPT-UHFFFAOYSA-N 50646038 CHEMBL5584048 Protein O-GlcNAcase Rat 6.9 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646038 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646038&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377672 519661440 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603323 CC(=O)Nc1ncc(CN2CCC(C#Cc3cc(F)c4c(c3)CCCN4)CC2)s1 InChI=1S/C22H25FN4OS/c1-15(28)26-22-25-13-19(29-22)14-27-9-6-16(7-10-27)4-5-17-11-18-3-2-8-24-21(18)20(23)12-17/h11-13,16,24H,2-3,6-10,14H2,1H3,(H,25,26,28) WQWMVVVYQFNXKX-UHFFFAOYSA-N 50646039 CHEMBL5593511 Protein O-GlcNAcase Rat 13 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646039 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646039&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 177377673 519661441 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603324 CC(=O)Nc1nc(F)c(CN2CC[C@H](OCc3nnc(C)o3)C[C@@H]2C)s1 InChI=1S/C16H22FN5O3S/c1-9-6-12(24-8-14-21-20-11(3)25-14)4-5-22(9)7-13-15(17)19-16(26-13)18-10(2)23/h9,12H,4-8H2,1-3H3,(H,18,19,23) OFNRINRWEARWEM-UHFFFAOYSA-N 50646040 CHEMBL5592978 Protein O-GlcNAcase Rat 23 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646040 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006743&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646040&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 135384249 519661442 1 MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9QEN,6PM9,5UHP,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_RAT Q8VIJ5 51603325 CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O\C1=N/OC(=O)Nc1ccccc1 |r| InChI=1S/C15H19N3O7/c1-8(20)16-11-13(22)12(21)10(7-19)24-14(11)18-25-15(23)17-9-5-3-2-4-6-9/h2-6,10-13,19,21-22H,7H2,1H3,(H,16,20)(H,17,23) PBLNJFVQMUMOJY-UHFFFAOYSA-N 50531967 Pugnac Protein O-GlcNAcase Homo sapiens 46 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50531967 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50531967&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 9576811 440740549 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9NE5,9NE4,9NE2,8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603326 CCNC1=N[C@H]2[C@H](O[C@H](CO)[C@@H](O)[C@@H]2O)S1 |r,t:3| InChI=1S/C9H16N2O4S/c1-2-10-9-11-5-7(14)6(13)4(3-12)15-8(5)16-9/h4-8,12-14H,2-3H2,1H3,(H,10,11) PPAIMZHKIXDJRN-UHFFFAOYSA-N 50323697 thiamet-G::(3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL::CHEMBL1213603::US9243020, (3aR,5R,6S,7R,7aR)-2-(ethylamino)-5-(hydroxymethyl)-3aH,5H,6H,7H,7aH-pyrano[3,2-d][1,3]thiazole-6,7-diol::US9695197, 0::US9815861, Example 098 Protein O-GlcNAcase Homo sapiens 21 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323697 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323697&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 24808478 117645018 CHEMBL1213603 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9NE5,9NE4,9NE2,8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603327 CC1CN(CC(=O)Nc2ccc(Cl)cc2)CCN1Cc1cnc(NC(C)=O)s1 InChI=1S/C19H24ClN5O2S/c1-13-10-24(12-18(27)23-16-5-3-15(20)4-6-16)7-8-25(13)11-17-9-21-19(28-17)22-14(2)26/h3-6,9,13H,7-8,10-12H2,1-2H3,(H,23,27)(H,21,22,26) IILJNGRUWDDWLI-UHFFFAOYSA-N 50592008 CHEMBL5171168::US20240018135, Code A-34 Protein O-GlcNAcase Homo sapiens 40 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50592008 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50592008&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 163368417 482602860 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 9NE5,9NE4,9NE2,8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603329 CC(=O)Nc1nc(F)c(CN2CC[C@H](OCc3noc(C)n3)C[C@@H]2C)s1 InChI=1S/C16H22FN5O3S/c1-9-6-12(24-8-14-19-11(3)25-21-14)4-5-22(9)7-13-15(17)20-16(26-13)18-10(2)23/h9,12H,4-8H2,1-3H3,(H,18,20,23) FRVXHWNHGWUTQO-UHFFFAOYSA-N 50646041 Ly-3372689::LY3372689::Ceperognastat Protein O-GlcNAcase Human 2.4 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646041 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646041&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search A1AKM 135260636 519661443 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0 51603330 CC(=O)Nc1nc(F)c(CN2CC[C@H](OCc3nnc(C)o3)C[C@@H]2C)s1 InChI=1S/C16H22FN5O3S/c1-9-6-12(24-8-14-21-20-11(3)25-14)4-5-22(9)7-13-15(17)19-16(26-13)18-10(2)23/h9,12H,4-8H2,1-3H3,(H,18,19,23) OFNRINRWEARWEM-UHFFFAOYSA-N 50646040 CHEMBL5592978 Protein O-GlcNAcase Human 2.1 ChEMBL 10.7270/Q2N58S2P 39109492 Cheng, Z; Shang, N; Wang, X; Kang, Y; Zhou, J; Lan, J; Hu, J; Peng, Y; Xu, B //0 10/12/2025 Chinese Academy of Medical Sciences and Peking Union Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50646040 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4424&target=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50646040&enzyme=Protein+O-GlcNAcase&column=ki&startPg=0&Increment=50&submit=Search 135384249 519661442 1 MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL 8P0L,7YEH,7OU6,5M7U,5M7T,5M7S,5M7R,9QEN,6PM9,5UHP,5UHO,5UHL,5UHK,5UN9,5TKE,5VVX,5VVV,5VVU,5VVT,5VVO,5UN8 Protein O-GlcNAcase OGA_HUMAN O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0