BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 51607993 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C29H26N6O2/c1-31-27(36)26(32-28(37)29(15-16-29)23-5-3-2-4-6-23)17-24-19-35(34-33-24)25-13-11-22(12-14-25)21-9-7-20(18-30)8-10-21/h2-14,19,26H,15-17H2,1H3,(H,31,36)(H,32,37) VYZKTQAFGPNQBW-UHFFFAOYSA-N 50648152 CHEMBL5598464 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 430 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648152 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648152&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379067 519663554 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51607994 CNC(=O)[C@H](Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C29H26N6O2/c1-31-27(36)26(32-28(37)29(15-16-29)23-5-3-2-4-6-23)17-24-19-35(34-33-24)25-13-11-22(12-14-25)21-9-7-20(18-30)8-10-21/h2-14,19,26H,15-17H2,1H3,(H,31,36)(H,32,37) VYZKTQAFGPNQBW-UHFFFAOYSA-N 50648153 CHEMBL5596137 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 230 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648153 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648153&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379068 519663555 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51607995 CNC(=O)[C@@H](Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C29H26N6O2/c1-31-27(36)26(32-28(37)29(15-16-29)23-5-3-2-4-6-23)17-24-19-35(34-33-24)25-13-11-22(12-14-25)21-9-7-20(18-30)8-10-21/h2-14,19,26H,15-17H2,1H3,(H,31,36)(H,32,37) VYZKTQAFGPNQBW-UHFFFAOYSA-N 50648154 CHEMBL5590641 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >5000 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648154 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648154&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379069 519663556 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51607996 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2F)CC1 InChI=1S/C29H25FN6O2/c1-32-27(37)26(33-28(38)29(14-15-29)24-4-2-3-5-25(24)30)16-22-18-36(35-34-22)23-12-10-21(11-13-23)20-8-6-19(17-31)7-9-20/h2-13,18,26H,14-16H2,1H3,(H,32,37)(H,33,38) HXMAGTHPIKFVSL-UHFFFAOYSA-N 50648155 CHEMBL5598139 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 920 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648155 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648155&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379070 519663557 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51607997 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2cccc(F)c2)CC1 InChI=1S/C29H25FN6O2/c1-32-27(37)26(33-28(38)29(13-14-29)22-3-2-4-23(30)15-22)16-24-18-36(35-34-24)25-11-9-21(10-12-25)20-7-5-19(17-31)6-8-20/h2-12,15,18,26H,13-14,16H2,1H3,(H,32,37)(H,33,38) QREQNCZEUBAOOX-UHFFFAOYSA-N 50648156 CHEMBL5596339 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 1220 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648156 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648156&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379071 519663558 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51607998 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccc(F)cc2)CC1 InChI=1S/C29H25FN6O2/c1-32-27(37)26(33-28(38)29(14-15-29)22-8-10-23(30)11-9-22)16-24-18-36(35-34-24)25-12-6-21(7-13-25)20-4-2-19(17-31)3-5-20/h2-13,18,26H,14-16H2,1H3,(H,32,37)(H,33,38) FQOPUEAWEZCQBF-UHFFFAOYSA-N 50648157 CHEMBL5598164 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 20320 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648157 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648157&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379072 519663559 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51607999 CNC(=O)/C(=C\c1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2C)CC1 InChI=1S/C30H26N6O2/c1-20-5-3-4-6-26(20)30(15-16-30)29(38)33-27(28(37)32-2)17-24-19-36(35-34-24)25-13-11-23(12-14-25)22-9-7-21(18-31)8-10-22/h3-14,17,19H,15-16H2,1-2H3,(H,32,37)(H,33,38) IDZQTLQFQJRLJK-UHFFFAOYSA-N 50648158 CHEMBL5597865 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 120 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648158 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648158&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379073 519663560 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608000 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2cccc(C)c2)CC1 InChI=1S/C30H28N6O2/c1-20-4-3-5-24(16-20)30(14-15-30)29(38)33-27(28(37)32-2)17-25-19-36(35-34-25)26-12-10-23(11-13-26)22-8-6-21(18-31)7-9-22/h3-13,16,19,27H,14-15,17H2,1-2H3,(H,32,37)(H,33,38) IDEONIWVCYOQED-UHFFFAOYSA-N 50648159 CHEMBL5590510 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 2720 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648159 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648159&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379074 519663561 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608001 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ncccc2C)CC1 InChI=1S/C29H27N7O2/c1-19-4-3-15-32-26(19)29(13-14-29)28(38)33-25(27(37)31-2)16-23-18-36(35-34-23)24-11-9-22(10-12-24)21-7-5-20(17-30)6-8-21/h3-12,15,18,25H,13-14,16H2,1-2H3,(H,31,37)(H,33,38) HTXWLTSAWFRCQK-UHFFFAOYSA-N 50648160 CHEMBL5590507 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 370 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648160 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648160&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379075 519663562 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608002 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2Cl)CC1 InChI=1S/C29H25ClN6O2/c1-32-27(37)26(33-28(38)29(14-15-29)24-4-2-3-5-25(24)30)16-22-18-36(35-34-22)23-12-10-21(11-13-23)20-8-6-19(17-31)7-9-20/h2-13,18,26H,14-16H2,1H3,(H,32,37)(H,33,38) OVOJGOCNXIQLBB-UHFFFAOYSA-N 50648161 CHEMBL5597961 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 780 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648161 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648161&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379076 519663563 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608003 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2Br)CC1 InChI=1S/C29H25BrN6O2/c1-32-27(37)26(33-28(38)29(14-15-29)24-4-2-3-5-25(24)30)16-22-18-36(35-34-22)23-12-10-21(11-13-23)20-8-6-19(17-31)7-9-20/h2-13,18,26H,14-16H2,1H3,(H,32,37)(H,33,38) NEOMMPXJGJTDNU-UHFFFAOYSA-N 50648162 CHEMBL5596995 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 3050 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648162 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648162&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379077 519663564 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608004 CCc1ccccc1C1(C(=O)NC(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)C(=O)NC)CC1 InChI=1S/C31H30N6O2/c1-3-22-6-4-5-7-27(22)31(16-17-31)30(39)34-28(29(38)33-2)18-25-20-37(36-35-25)26-14-12-24(13-15-26)23-10-8-21(19-32)9-11-23/h4-15,20,28H,3,16-18H2,1-2H3,(H,33,38)(H,34,39) PZMCUKWSZUYKNT-UHFFFAOYSA-N 50648163 CHEMBL5597013 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 3100 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648163 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648163&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379078 519663565 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608005 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2OC)CC1 InChI=1S/C30H28N6O3/c1-32-28(37)26(33-29(38)30(15-16-30)25-5-3-4-6-27(25)39-2)17-23-19-36(35-34-23)24-13-11-22(12-14-24)21-9-7-20(18-31)8-10-21/h3-14,19,26H,15-17H2,1-2H3,(H,32,37)(H,33,38) COYNCHZYDOKQEB-UHFFFAOYSA-N 50648164 CHEMBL5597041 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 6860 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648164 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648164&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379079 519663566 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608006 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2C(F)(F)F)CC1 InChI=1S/C30H25F3N6O2/c1-35-27(40)26(36-28(41)29(14-15-29)24-4-2-3-5-25(24)30(31,32)33)16-22-18-39(38-37-22)23-12-10-21(11-13-23)20-8-6-19(17-34)7-9-20/h2-13,18,26H,14-16H2,1H3,(H,35,40)(H,36,41) AVPYBFXKRIGEBO-UHFFFAOYSA-N 50648165 CHEMBL5596868 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 13100 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648165 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648165&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379080 519663567 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608007 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2C#N)CC1 InChI=1S/C30H25N7O2/c1-33-28(38)27(34-29(39)30(14-15-30)26-5-3-2-4-23(26)18-32)16-24-19-37(36-35-24)25-12-10-22(11-13-25)21-8-6-20(17-31)7-9-21/h2-13,19,27H,14-16H2,1H3,(H,33,38)(H,34,39) BAYNEOHPBDBQNS-UHFFFAOYSA-N 50648166 CHEMBL5597668 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 50980 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648166 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648166&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379081 519663568 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608008 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C(C)(C)c1ccccc1 InChI=1S/C29H28N6O2/c1-29(2,23-7-5-4-6-8-23)28(37)32-26(27(36)31-3)17-24-19-35(34-33-24)25-15-13-22(14-16-25)21-11-9-20(18-30)10-12-21/h4-16,19,26H,17H2,1-3H3,(H,31,36)(H,32,37) YVSJBDBSWOGXCW-UHFFFAOYSA-N 50648167 CHEMBL5598046 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 2930 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648167 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648167&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379082 519663569 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608009 CNC(=O)C(Cc1cn(-c2ccc(-c3ccccc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C28H27N5O2/c1-29-26(34)25(30-27(35)28(16-17-28)22-10-6-3-7-11-22)18-23-19-33(32-31-23)24-14-12-21(13-15-24)20-8-4-2-5-9-20/h2-15,19,25H,16-18H2,1H3,(H,29,34)(H,30,35) HXHLFDUUFQZTEW-UHFFFAOYSA-N 50648168 CHEMBL5597112 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 4880 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648168 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648168&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379083 519663570 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608010 CNC(=O)C(Cc1cn(-c2ccc(-c3ccccn3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C27H26N6O2/c1-28-25(34)24(30-26(35)27(14-15-27)20-7-3-2-4-8-20)17-21-18-33(32-31-21)22-12-10-19(11-13-22)23-9-5-6-16-29-23/h2-13,16,18,24H,14-15,17H2,1H3,(H,28,34)(H,30,35) KZMWYTDAATXKAX-UHFFFAOYSA-N 50648169 CHEMBL5597275 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 3370 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648169 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648169&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379084 519663571 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608011 CNC(=O)C(Cc1cn(-c2ccc(-c3cccnc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C27H26N6O2/c1-28-25(34)24(30-26(35)27(13-14-27)21-7-3-2-4-8-21)16-22-18-33(32-31-22)23-11-9-19(10-12-23)20-6-5-15-29-17-20/h2-12,15,17-18,24H,13-14,16H2,1H3,(H,28,34)(H,30,35) HMEASBBVEWPHRG-UHFFFAOYSA-N 50648170 CHEMBL5596720 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 21220 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648170 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648170&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379085 519663572 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608012 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cn3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C28H25N7O2/c1-30-26(36)25(32-27(37)28(13-14-28)21-5-3-2-4-6-21)15-22-18-35(34-33-22)23-10-8-20(9-11-23)24-12-7-19(16-29)17-31-24/h2-12,17-18,25H,13-15H2,1H3,(H,30,36)(H,32,37) ZZBNWNUSPWQORY-UHFFFAOYSA-N 50648171 CHEMBL5596872 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 2770 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648171 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648171&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379086 519663573 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608013 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(N4CCN(C)CC4)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C33H37N7O2/c1-34-31(41)30(35-32(42)33(16-17-33)26-6-4-3-5-7-26)22-27-23-40(37-36-27)29-14-10-25(11-15-29)24-8-12-28(13-9-24)39-20-18-38(2)19-21-39/h3-15,23,30H,16-22H2,1-2H3,(H,34,41)(H,35,42) HSTUBFKESJYWEQ-UHFFFAOYSA-N 50648172 CHEMBL5597735 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 3190 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648172 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648172&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379087 519663574 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608014 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(CN4CCN(C)CC4)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C34H39N7O2/c1-35-32(42)31(36-33(43)34(16-17-34)28-6-4-3-5-7-28)22-29-24-41(38-37-29)30-14-12-27(13-15-30)26-10-8-25(9-11-26)23-40-20-18-39(2)19-21-40/h3-15,24,31H,16-23H2,1-2H3,(H,35,42)(H,36,43) WURSSCMYPWOVTI-UHFFFAOYSA-N 50648173 CHEMBL5597324 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 2060 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648173 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648173&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379088 519663575 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608015 CNC(=O)C(Cc1cn(-c2ccc3ccccc3c2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C26H25N5O2/c1-27-24(32)23(28-25(33)26(13-14-26)20-9-3-2-4-10-20)16-21-17-31(30-29-21)22-12-11-18-7-5-6-8-19(18)15-22/h2-12,15,17,23H,13-14,16H2,1H3,(H,27,32)(H,28,33) GJMWRXVJXLUBRR-UHFFFAOYSA-N 50648174 CHEMBL5598541 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 11060 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648174 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648174&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379089 519663576 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608016 CNC(=O)C(Cc1cn(-c2csc3ccccc23)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C24H23N5O2S/c1-25-22(30)19(26-23(31)24(11-12-24)16-7-3-2-4-8-16)13-17-14-29(28-27-17)20-15-32-21-10-6-5-9-18(20)21/h2-10,14-15,19H,11-13H2,1H3,(H,25,30)(H,26,31) DKZBRHZOFOTRNJ-UHFFFAOYSA-N 50648175 CHEMBL5596997 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >12500 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648175 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648175&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379090 519663577 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608017 CNC(=O)C(Cc1cn(Cc2cc3ccccc3s2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C25H25N5O2S/c1-26-23(31)21(27-24(32)25(11-12-25)18-8-3-2-4-9-18)14-19-15-30(29-28-19)16-20-13-17-7-5-6-10-22(17)33-20/h2-10,13,15,21H,11-12,14,16H2,1H3,(H,26,31)(H,27,32) QTEREOJUDHFRGC-UHFFFAOYSA-N 50648176 CHEMBL5597202 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >50000 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648176 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648176&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379091 519663578 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608018 CNC(=O)C(Cc1cn(-c2ccccc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C22H23N5O2/c1-23-20(28)19(14-17-15-27(26-25-17)18-10-6-3-7-11-18)24-21(29)22(12-13-22)16-8-4-2-5-9-16/h2-11,15,19H,12-14H2,1H3,(H,23,28)(H,24,29) MWPZIHNAFGBGBH-UHFFFAOYSA-N 50648177 CHEMBL5596679 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 29780 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648177 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648177&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379092 519663579 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608019 CNC(=O)C(Cc1cn(-c2ccn(C)n2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C20H23N7O2/c1-21-18(28)16(12-15-13-27(25-23-15)17-8-11-26(2)24-17)22-19(29)20(9-10-20)14-6-4-3-5-7-14/h3-8,11,13,16H,9-10,12H2,1-2H3,(H,21,28)(H,22,29) OLJWCIJGKNKVAT-UHFFFAOYSA-N 50648178 CHEMBL5596259 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 39290 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648178 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648178&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379093 519663580 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608020 CC(C)NC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C31H30N6O2/c1-21(2)33-29(38)28(34-30(39)31(16-17-31)25-6-4-3-5-7-25)18-26-20-37(36-35-26)27-14-12-24(13-15-27)23-10-8-22(19-32)9-11-23/h3-15,20-21,28H,16-18H2,1-2H3,(H,33,38)(H,34,39) NSEXQMDWKHPWPE-UHFFFAOYSA-N 50648179 CHEMBL5598310 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 6110 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648179 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648179&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379094 519663581 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608021 N#Cc1ccc(-c2ccc(-n3cc(CC(NC(=O)C4(c5ccccc5)CC4)C(=O)NC4CC(O)C4)nn3)cc2)cc1 InChI=1S/C32H30N6O3/c33-19-21-6-8-22(9-7-21)23-10-12-27(13-11-23)38-20-26(36-37-38)18-29(30(40)34-25-16-28(39)17-25)35-31(41)32(14-15-32)24-4-2-1-3-5-24/h1-13,20,25,28-29,39H,14-18H2,(H,34,40)(H,35,41) LVSHHZHUWFBHGX-UHFFFAOYSA-N 50648180 CHEMBL5589996 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 130 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648180 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648180&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379095 519663582 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608022 CN1CCC(NC(=O)C(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)NC(=O)C2(c3ccccc3)CC2)CC1 InChI=1S/C34H35N7O2/c1-40-19-15-28(16-20-40)36-32(42)31(37-33(43)34(17-18-34)27-5-3-2-4-6-27)21-29-23-41(39-38-29)30-13-11-26(12-14-30)25-9-7-24(22-35)8-10-25/h2-14,23,28,31H,15-21H2,1H3,(H,36,42)(H,37,43) XUDSPKLHGGAHOB-UHFFFAOYSA-N 50648181 CHEMBL5597295 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 140 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648181 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648181&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379096 519663583 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608023 CC(=O)N1CCC(NC(=O)C(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)NC(=O)C2(c3ccccc3)CC2)CC1 InChI=1S/C35H35N7O3/c1-24(43)41-19-15-29(16-20-41)37-33(44)32(38-34(45)35(17-18-35)28-5-3-2-4-6-28)21-30-23-42(40-39-30)31-13-11-27(12-14-31)26-9-7-25(22-36)8-10-26/h2-14,23,29,32H,15-21H2,1H3,(H,37,44)(H,38,45) AWONBQRZORTHIO-UHFFFAOYSA-N 50648182 CHEMBL5596391 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 270 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648182 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648182&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379097 519663584 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608024 Cc1ccccc1C1(C(=O)NC(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)C(=O)N2CC(O)C2)CC1 InChI=1S/C32H30N6O3/c1-21-4-2-3-5-28(21)32(14-15-32)31(41)34-29(30(40)37-19-27(39)20-37)16-25-18-38(36-35-25)26-12-10-24(11-13-26)23-8-6-22(17-33)7-9-23/h2-13,18,27,29,39H,14-16,19-20H2,1H3,(H,34,41) RLNMVTKCUHXSIF-UHFFFAOYSA-N 50648183 CHEMBL5598321 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 420 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648183 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648183&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379098 519663585 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608025 Cc1ccccc1C1(C(=O)NC(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)C(=O)NC2CC(O)C2)CC1 InChI=1S/C33H32N6O3/c1-21-4-2-3-5-29(21)33(14-15-33)32(42)36-30(31(41)35-25-16-28(40)17-25)18-26-20-39(38-37-26)27-12-10-24(11-13-27)23-8-6-22(19-34)7-9-23/h2-13,20,25,28,30,40H,14-18H2,1H3,(H,35,41)(H,36,42) KRGJQWGEXXUEAO-UHFFFAOYSA-N 50648184 CHEMBL5598027 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 93 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648184 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648184&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379099 519663586 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608026 Cc1ccccc1C1(C(=O)NC(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)C(=O)N2CCN(C)CC2)CC1 InChI=1S/C34H35N7O2/c1-24-5-3-4-6-30(24)34(15-16-34)33(43)36-31(32(42)40-19-17-39(2)18-20-40)21-28-23-41(38-37-28)29-13-11-27(12-14-29)26-9-7-25(22-35)8-10-26/h3-14,23,31H,15-21H2,1-2H3,(H,36,43) URVWOTBQUBVUEH-UHFFFAOYSA-N 50648185 CHEMBL5598364 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 640 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648185 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648185&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379100 519663587 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608027 CC(=O)N1CCN(C(=O)C(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)NC(=O)C2(c3ccccc3C)CC2)CC1 InChI=1S/C35H35N7O3/c1-24-5-3-4-6-31(24)35(15-16-35)34(45)37-32(33(44)41-19-17-40(18-20-41)25(2)43)21-29-23-42(39-38-29)30-13-11-28(12-14-30)27-9-7-26(22-36)8-10-27/h3-14,23,32H,15-21H2,1-2H3,(H,37,45) KHVHOCWYHZZEHY-UHFFFAOYSA-N 50648186 CHEMBL5596439 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 440 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648186 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648186&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379101 519663588 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608028 Cc1ccccc1C1(C(=O)NC(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)C(=O)NC2CCN(C)CC2)CC1 InChI=1S/C35H37N7O2/c1-24-5-3-4-6-31(24)35(17-18-35)34(44)38-32(33(43)37-28-15-19-41(2)20-16-28)21-29-23-42(40-39-29)30-13-11-27(12-14-30)26-9-7-25(22-36)8-10-26/h3-14,23,28,32H,15-21H2,1-2H3,(H,37,43)(H,38,44) QMUZXRGNTODESB-UHFFFAOYSA-N 50648187 CHEMBL5591180 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 25 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648187 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648187&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 172638559 519663589 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608029 CC(=O)N1CCC(NC(=O)C(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)NC(=O)C2(c3ccccc3C)CC2)CC1 InChI=1S/C36H37N7O3/c1-24-5-3-4-6-32(24)36(17-18-36)35(46)39-33(34(45)38-29-15-19-42(20-16-29)25(2)44)21-30-23-43(41-40-30)31-13-11-28(12-14-31)27-9-7-26(22-37)8-10-27/h3-14,23,29,33H,15-21H2,1-2H3,(H,38,45)(H,39,46) QXTAQFWEVNZONP-UHFFFAOYSA-N 50648188 CHEMBL5597140 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 87 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648188 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648188&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379102 519663590 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608030 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C29H26N6O2/c1-31-27(36)26(32-28(37)29(15-16-29)23-5-3-2-4-6-23)17-24-19-35(34-33-24)25-13-11-22(12-14-25)21-9-7-20(18-30)8-10-21/h2-14,19,26H,15-17H2,1H3,(H,31,36)(H,32,37) VYZKTQAFGPNQBW-UHFFFAOYSA-N 50648152 CHEMBL5598464 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 420 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648152 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648152&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379067 519663554 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608031 CNC(=O)[C@H](Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C29H26N6O2/c1-31-27(36)26(32-28(37)29(15-16-29)23-5-3-2-4-6-23)17-24-19-35(34-33-24)25-13-11-22(12-14-25)21-9-7-20(18-30)8-10-21/h2-14,19,26H,15-17H2,1H3,(H,31,36)(H,32,37) VYZKTQAFGPNQBW-UHFFFAOYSA-N 50648153 CHEMBL5596137 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 390 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648153 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648153&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379068 519663555 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608032 CNC(=O)[C@@H](Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C29H26N6O2/c1-31-27(36)26(32-28(37)29(15-16-29)23-5-3-2-4-6-23)17-24-19-35(34-33-24)25-13-11-22(12-14-25)21-9-7-20(18-30)8-10-21/h2-14,19,26H,15-17H2,1H3,(H,31,36)(H,32,37) VYZKTQAFGPNQBW-UHFFFAOYSA-N 50648154 CHEMBL5590641 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >33300 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648154 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648154&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379069 519663556 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608033 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2F)CC1 InChI=1S/C29H25FN6O2/c1-32-27(37)26(33-28(38)29(14-15-29)24-4-2-3-5-25(24)30)16-22-18-36(35-34-22)23-12-10-21(11-13-23)20-8-6-19(17-31)7-9-20/h2-13,18,26H,14-16H2,1H3,(H,32,37)(H,33,38) HXMAGTHPIKFVSL-UHFFFAOYSA-N 50648155 CHEMBL5598139 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 1260 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648155 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648155&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379070 519663557 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608034 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2cccc(F)c2)CC1 InChI=1S/C29H25FN6O2/c1-32-27(37)26(33-28(38)29(13-14-29)22-3-2-4-23(30)15-22)16-24-18-36(35-34-24)25-11-9-21(10-12-25)20-7-5-19(17-31)6-8-20/h2-12,15,18,26H,13-14,16H2,1H3,(H,32,37)(H,33,38) QREQNCZEUBAOOX-UHFFFAOYSA-N 50648156 CHEMBL5596339 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 2940 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648156 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648156&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379071 519663558 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608035 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccc(F)cc2)CC1 InChI=1S/C29H25FN6O2/c1-32-27(37)26(33-28(38)29(14-15-29)22-8-10-23(30)11-9-22)16-24-18-36(35-34-24)25-12-6-21(7-13-25)20-4-2-19(17-31)3-5-20/h2-13,18,26H,14-16H2,1H3,(H,32,37)(H,33,38) FQOPUEAWEZCQBF-UHFFFAOYSA-N 50648157 CHEMBL5598164 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 17240 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648157 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648157&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379072 519663559 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608036 CNC(=O)/C(=C\c1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2C)CC1 InChI=1S/C30H26N6O2/c1-20-5-3-4-6-26(20)30(15-16-30)29(38)33-27(28(37)32-2)17-24-19-36(35-34-24)25-13-11-23(12-14-25)22-9-7-21(18-31)8-10-22/h3-14,17,19H,15-16H2,1-2H3,(H,32,37)(H,33,38) IDZQTLQFQJRLJK-UHFFFAOYSA-N 50648158 CHEMBL5597865 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 250 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648158 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648158&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379073 519663560 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608037 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2cccc(C)c2)CC1 InChI=1S/C30H28N6O2/c1-20-4-3-5-24(16-20)30(14-15-30)29(38)33-27(28(37)32-2)17-25-19-36(35-34-25)26-12-10-23(11-13-26)22-8-6-21(18-31)7-9-22/h3-13,16,19,27H,14-15,17H2,1-2H3,(H,32,37)(H,33,38) IDEONIWVCYOQED-UHFFFAOYSA-N 50648159 CHEMBL5590510 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 1930 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648159 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648159&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379074 519663561 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608038 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ncccc2C)CC1 InChI=1S/C29H27N7O2/c1-19-4-3-15-32-26(19)29(13-14-29)28(38)33-25(27(37)31-2)16-23-18-36(35-34-23)24-11-9-22(10-12-24)21-7-5-20(17-30)6-8-21/h3-12,15,18,25H,13-14,16H2,1-2H3,(H,31,37)(H,33,38) HTXWLTSAWFRCQK-UHFFFAOYSA-N 50648160 CHEMBL5590507 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 360 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648160 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648160&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379075 519663562 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608039 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2Cl)CC1 InChI=1S/C29H25ClN6O2/c1-32-27(37)26(33-28(38)29(14-15-29)24-4-2-3-5-25(24)30)16-22-18-36(35-34-22)23-12-10-21(11-13-23)20-8-6-19(17-31)7-9-20/h2-13,18,26H,14-16H2,1H3,(H,32,37)(H,33,38) OVOJGOCNXIQLBB-UHFFFAOYSA-N 50648161 CHEMBL5597961 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 2530 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648161 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648161&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379076 519663563 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608040 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2Br)CC1 InChI=1S/C29H25BrN6O2/c1-32-27(37)26(33-28(38)29(14-15-29)24-4-2-3-5-25(24)30)16-22-18-36(35-34-22)23-12-10-21(11-13-23)20-8-6-19(17-31)7-9-20/h2-13,18,26H,14-16H2,1H3,(H,32,37)(H,33,38) NEOMMPXJGJTDNU-UHFFFAOYSA-N 50648162 CHEMBL5596995 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 640 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648162 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648162&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379077 519663564 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608041 CCc1ccccc1C1(C(=O)NC(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)C(=O)NC)CC1 InChI=1S/C31H30N6O2/c1-3-22-6-4-5-7-27(22)31(16-17-31)30(39)34-28(29(38)33-2)18-25-20-37(36-35-25)26-14-12-24(13-15-26)23-10-8-21(19-32)9-11-23/h4-15,20,28H,3,16-18H2,1-2H3,(H,33,38)(H,34,39) PZMCUKWSZUYKNT-UHFFFAOYSA-N 50648163 CHEMBL5597013 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 1670 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648163 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648163&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379078 519663565 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608042 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2OC)CC1 InChI=1S/C30H28N6O3/c1-32-28(37)26(33-29(38)30(15-16-30)25-5-3-4-6-27(25)39-2)17-23-19-36(35-34-23)24-13-11-22(12-14-24)21-9-7-20(18-31)8-10-21/h3-14,19,26H,15-17H2,1-2H3,(H,32,37)(H,33,38) COYNCHZYDOKQEB-UHFFFAOYSA-N 50648164 CHEMBL5597041 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 5540 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648164 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648164&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379079 519663566 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608043 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2C(F)(F)F)CC1 InChI=1S/C30H25F3N6O2/c1-35-27(40)26(36-28(41)29(14-15-29)24-4-2-3-5-25(24)30(31,32)33)16-22-18-39(38-37-22)23-12-10-21(11-13-23)20-8-6-19(17-34)7-9-20/h2-13,18,26H,14-16H2,1H3,(H,35,40)(H,36,41) AVPYBFXKRIGEBO-UHFFFAOYSA-N 50648165 CHEMBL5596868 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 6600 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648165 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648165&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379080 519663567 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608044 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2C#N)CC1 InChI=1S/C30H25N7O2/c1-33-28(38)27(34-29(39)30(14-15-30)26-5-3-2-4-23(26)18-32)16-24-19-37(36-35-24)25-12-10-22(11-13-25)21-8-6-20(17-31)7-9-21/h2-13,19,27H,14-16H2,1H3,(H,33,38)(H,34,39) BAYNEOHPBDBQNS-UHFFFAOYSA-N 50648166 CHEMBL5597668 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >100000 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648166 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648166&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379081 519663568 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608045 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)Cc1ccccc1 InChI=1S/C27H24N6O2/c1-29-27(35)25(30-26(34)15-19-5-3-2-4-6-19)16-23-18-33(32-31-23)24-13-11-22(12-14-24)21-9-7-20(17-28)8-10-21/h2-14,18,25H,15-16H2,1H3,(H,29,35)(H,30,34) RGFVQTLLZGGRQM-UHFFFAOYSA-N 50648189 CHEMBL5597598 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >100000 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648189 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648189&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379103 519663591 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608046 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C(C)(C)c1ccccc1 InChI=1S/C29H28N6O2/c1-29(2,23-7-5-4-6-8-23)28(37)32-26(27(36)31-3)17-24-19-35(34-33-24)25-15-13-22(14-16-25)21-11-9-20(18-30)10-12-21/h4-16,19,26H,17H2,1-3H3,(H,31,36)(H,32,37) YVSJBDBSWOGXCW-UHFFFAOYSA-N 50648167 CHEMBL5598046 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 2090 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648167 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648167&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379082 519663569 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608047 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CCC1 InChI=1S/C30H28N6O2/c1-32-28(37)27(33-29(38)30(16-5-17-30)24-6-3-2-4-7-24)18-25-20-36(35-34-25)26-14-12-23(13-15-26)22-10-8-21(19-31)9-11-22/h2-4,6-15,20,27H,5,16-18H2,1H3,(H,32,37)(H,33,38) FCSHMEGCUJVNBF-UHFFFAOYSA-N 50648190 CHEMBL5596526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >100000 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648190 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648190&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379104 519663592 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608048 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CCCC1 InChI=1S/C31H30N6O2/c1-33-29(38)28(34-30(39)31(17-5-6-18-31)25-7-3-2-4-8-25)19-26-21-37(36-35-26)27-15-13-24(14-16-27)23-11-9-22(20-32)10-12-23/h2-4,7-16,21,28H,5-6,17-19H2,1H3,(H,33,38)(H,34,39) GYAJRICUIFQQTL-UHFFFAOYSA-N 50648191 CHEMBL5589890 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >100000 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648191 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648191&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379105 519663593 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608049 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CCCCC1 InChI=1S/C32H32N6O2/c1-34-30(39)29(35-31(40)32(18-6-3-7-19-32)26-8-4-2-5-9-26)20-27-22-38(37-36-27)28-16-14-25(15-17-28)24-12-10-23(21-33)11-13-24/h2,4-5,8-17,22,29H,3,6-7,18-20H2,1H3,(H,34,39)(H,35,40) OBKADHPQSBMNJS-UHFFFAOYSA-N 50648192 CHEMBL5597398 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >100000 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648192 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648192&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379106 519663594 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608050 CNC(=O)C(Cc1cn(-c2ccc(-c3ccccc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C28H27N5O2/c1-29-26(34)25(30-27(35)28(16-17-28)22-10-6-3-7-11-22)18-23-19-33(32-31-23)24-14-12-21(13-15-24)20-8-4-2-5-9-20/h2-15,19,25H,16-18H2,1H3,(H,29,34)(H,30,35) HXHLFDUUFQZTEW-UHFFFAOYSA-N 50648168 CHEMBL5597112 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 42560 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648168 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648168&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379083 519663570 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608051 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cn3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C28H25N7O2/c1-30-26(36)25(32-27(37)28(13-14-28)21-5-3-2-4-6-21)15-22-18-35(34-33-22)23-10-8-20(9-11-23)24-12-7-19(16-29)17-31-24/h2-12,17-18,25H,13-15H2,1H3,(H,30,36)(H,32,37) ZZBNWNUSPWQORY-UHFFFAOYSA-N 50648171 CHEMBL5596872 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 3310 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648171 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648171&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379086 519663573 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608052 CNC(=O)C(Cc1cn(-c2ccc(-c3ncc(C#N)cn3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C27H24N8O2/c1-29-25(36)23(32-26(37)27(11-12-27)20-5-3-2-4-6-20)13-21-17-35(34-33-21)22-9-7-19(8-10-22)24-30-15-18(14-28)16-31-24/h2-10,15-17,23H,11-13H2,1H3,(H,29,36)(H,32,37) ABNKIAVFFDAJQB-UHFFFAOYSA-N 50648193 CHEMBL5597756 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 25730 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648193 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648193&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379107 519663595 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608053 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(N4CCN(C)CC4)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C33H37N7O2/c1-34-31(41)30(35-32(42)33(16-17-33)26-6-4-3-5-7-26)22-27-23-40(37-36-27)29-14-10-25(11-15-29)24-8-12-28(13-9-24)39-20-18-38(2)19-21-39/h3-15,23,30H,16-22H2,1-2H3,(H,34,41)(H,35,42) HSTUBFKESJYWEQ-UHFFFAOYSA-N 50648172 CHEMBL5597735 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 17850 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648172 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648172&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379087 519663574 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608054 CNC(=O)C(Cc1cn(-c2ccc(-c3ccc(CN4CCN(C)CC4)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C34H39N7O2/c1-35-32(42)31(36-33(43)34(16-17-34)28-6-4-3-5-7-28)22-29-24-41(38-37-29)30-14-12-27(13-15-30)26-10-8-25(9-11-26)23-40-20-18-39(2)19-21-40/h3-15,24,31H,16-23H2,1-2H3,(H,35,42)(H,36,43) WURSSCMYPWOVTI-UHFFFAOYSA-N 50648173 CHEMBL5597324 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 3520 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648173 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648173&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379088 519663575 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608055 CNC(=O)C(Cc1cn(-c2ccc(C3CCN(C)CC3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C28H34N6O2/c1-29-26(35)25(30-27(36)28(14-15-28)22-6-4-3-5-7-22)18-23-19-34(32-31-23)24-10-8-20(9-11-24)21-12-16-33(2)17-13-21/h3-11,19,21,25H,12-18H2,1-2H3,(H,29,35)(H,30,36) YGCXDTNCOYRFPQ-UHFFFAOYSA-N 50648194 CHEMBL5597691 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >100000 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648194 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648194&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379108 519663596 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608056 CNC(=O)C(Cc1cn(-c2ccc3ccccc3c2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C26H25N5O2/c1-27-24(32)23(28-25(33)26(13-14-26)20-9-3-2-4-10-20)16-21-17-31(30-29-21)22-12-11-18-7-5-6-8-19(18)15-22/h2-12,15,17,23H,13-14,16H2,1H3,(H,27,32)(H,28,33) GJMWRXVJXLUBRR-UHFFFAOYSA-N 50648174 CHEMBL5598541 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 27580 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648174 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648174&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379089 519663576 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608057 CNC(=O)C(Cc1cn(-c2csc3ccccc23)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C24H23N5O2S/c1-25-22(30)19(26-23(31)24(11-12-24)16-7-3-2-4-8-16)13-17-14-29(28-27-17)20-15-32-21-10-6-5-9-18(20)21/h2-10,14-15,19H,11-13H2,1H3,(H,25,30)(H,26,31) DKZBRHZOFOTRNJ-UHFFFAOYSA-N 50648175 CHEMBL5596997 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 62720 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648175 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648175&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379090 519663577 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608058 CNC(=O)C(Cc1cn(Cc2cc3ccccc3s2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C25H25N5O2S/c1-26-23(31)21(27-24(32)25(11-12-25)18-8-3-2-4-9-18)14-19-15-30(29-28-19)16-20-13-17-7-5-6-10-22(17)33-20/h2-10,13,15,21H,11-12,14,16H2,1H3,(H,26,31)(H,27,32) QTEREOJUDHFRGC-UHFFFAOYSA-N 50648176 CHEMBL5597202 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >100000 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648176 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648176&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379091 519663578 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608059 CNC(=O)C(Cc1cn(-c2ccccc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C22H23N5O2/c1-23-20(28)19(14-17-15-27(26-25-17)18-10-6-3-7-11-18)24-21(29)22(12-13-22)16-8-4-2-5-9-16/h2-11,15,19H,12-14H2,1H3,(H,23,28)(H,24,29) MWPZIHNAFGBGBH-UHFFFAOYSA-N 50648177 CHEMBL5596679 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >10000 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648177 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648177&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379092 519663579 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608060 CNC(=O)C(Cc1cn(-c2ccn(C)n2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C20H23N7O2/c1-21-18(28)16(12-15-13-27(25-23-15)17-8-11-26(2)24-17)22-19(29)20(9-10-20)14-6-4-3-5-7-14/h3-8,11,13,16H,9-10,12H2,1-2H3,(H,21,28)(H,22,29) OLJWCIJGKNKVAT-UHFFFAOYSA-N 50648178 CHEMBL5596259 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >10000 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648178 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648178&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379093 519663580 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608061 CC(C)NC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C31H30N6O2/c1-21(2)33-29(38)28(34-30(39)31(16-17-31)25-6-4-3-5-7-25)18-26-20-37(36-35-26)27-14-12-24(13-15-27)23-10-8-22(19-32)9-11-23/h3-15,20-21,28H,16-18H2,1-2H3,(H,33,38)(H,34,39) NSEXQMDWKHPWPE-UHFFFAOYSA-N 50648179 CHEMBL5598310 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 8150 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648179 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648179&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379094 519663581 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608062 CC(C)(C)NC(=O)C(Cc1cn(-c2ccc(-c3ccc(C#N)cc3)cc2)nn1)NC(=O)C1(c2ccccc2)CC1 InChI=1S/C32H32N6O2/c1-31(2,3)35-29(39)28(34-30(40)32(17-18-32)25-7-5-4-6-8-25)19-26-21-38(37-36-26)27-15-13-24(14-16-27)23-11-9-22(20-33)10-12-23/h4-16,21,28H,17-19H2,1-3H3,(H,34,40)(H,35,39) HNOOCJMNRPCCAF-UHFFFAOYSA-N 50648195 CHEMBL5598482 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human >100000 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648195 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648195&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379109 519663597 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608063 N#Cc1ccc(-c2ccc(-n3cc(CC(NC(=O)C4(c5ccccc5)CC4)C(=O)NC4CC(O)C4)nn3)cc2)cc1 InChI=1S/C32H30N6O3/c33-19-21-6-8-22(9-7-21)23-10-12-27(13-11-23)38-20-26(36-37-38)18-29(30(40)34-25-16-28(39)17-25)35-31(41)32(14-15-32)24-4-2-1-3-5-24/h1-13,20,25,28-29,39H,14-18H2,(H,34,40)(H,35,41) LVSHHZHUWFBHGX-UHFFFAOYSA-N 50648180 CHEMBL5589996 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 660 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648180 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648180&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379095 519663582 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608064 CN1CCC(NC(=O)C(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)NC(=O)C2(c3ccccc3)CC2)CC1 InChI=1S/C34H35N7O2/c1-40-19-15-28(16-20-40)36-32(42)31(37-33(43)34(17-18-34)27-5-3-2-4-6-27)21-29-23-41(39-38-29)30-13-11-26(12-14-30)25-9-7-24(22-35)8-10-25/h2-14,23,28,31H,15-21H2,1H3,(H,36,42)(H,37,43) XUDSPKLHGGAHOB-UHFFFAOYSA-N 50648181 CHEMBL5597295 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 480 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648181 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648181&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379096 519663583 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608065 CC(=O)N1CCC(NC(=O)C(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)NC(=O)C2(c3ccccc3)CC2)CC1 InChI=1S/C35H35N7O3/c1-24(43)41-19-15-29(16-20-41)37-33(44)32(38-34(45)35(17-18-35)28-5-3-2-4-6-28)21-30-23-42(40-39-30)31-13-11-27(12-14-31)26-9-7-25(22-36)8-10-26/h2-14,23,29,32H,15-21H2,1H3,(H,37,44)(H,38,45) AWONBQRZORTHIO-UHFFFAOYSA-N 50648182 CHEMBL5596391 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 1370 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648182 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648182&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379097 519663584 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608066 Cc1ccccc1C1(C(=O)NC(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)C(=O)N2CC(O)C2)CC1 InChI=1S/C32H30N6O3/c1-21-4-2-3-5-28(21)32(14-15-32)31(41)34-29(30(40)37-19-27(39)20-37)16-25-18-38(36-35-25)26-12-10-24(11-13-26)23-8-6-22(17-33)7-9-23/h2-13,18,27,29,39H,14-16,19-20H2,1H3,(H,34,41) RLNMVTKCUHXSIF-UHFFFAOYSA-N 50648183 CHEMBL5598321 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 800 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648183 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648183&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379098 519663585 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608067 Cc1ccccc1C1(C(=O)NC(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)C(=O)NC2CC(O)C2)CC1 InChI=1S/C33H32N6O3/c1-21-4-2-3-5-29(21)33(14-15-33)32(42)36-30(31(41)35-25-16-28(40)17-25)18-26-20-39(38-37-26)27-12-10-24(11-13-27)23-8-6-22(19-34)7-9-23/h2-13,20,25,28,30,40H,14-18H2,1H3,(H,35,41)(H,36,42) KRGJQWGEXXUEAO-UHFFFAOYSA-N 50648184 CHEMBL5598027 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 220 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648184 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648184&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379099 519663586 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608068 Cc1ccccc1C1(C(=O)NC(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)C(=O)N2CCN(C)CC2)CC1 InChI=1S/C34H35N7O2/c1-24-5-3-4-6-30(24)34(15-16-34)33(43)36-31(32(42)40-19-17-39(2)18-20-40)21-28-23-41(38-37-28)29-13-11-27(12-14-29)26-9-7-25(22-35)8-10-26/h3-14,23,31H,15-21H2,1-2H3,(H,36,43) URVWOTBQUBVUEH-UHFFFAOYSA-N 50648185 CHEMBL5598364 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 1680 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648185 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648185&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379100 519663587 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608069 CC(=O)N1CCN(C(=O)C(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)NC(=O)C2(c3ccccc3C)CC2)CC1 InChI=1S/C35H35N7O3/c1-24-5-3-4-6-31(24)35(15-16-35)34(45)37-32(33(44)41-19-17-40(18-20-41)25(2)43)21-29-23-42(39-38-29)30-13-11-28(12-14-30)27-9-7-26(22-36)8-10-27/h3-14,23,32H,15-21H2,1-2H3,(H,37,45) KHVHOCWYHZZEHY-UHFFFAOYSA-N 50648186 CHEMBL5596439 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 1190 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648186 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648186&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379101 519663588 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608070 Cc1ccccc1C1(C(=O)NC(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)C(=O)NC2CCN(C)CC2)CC1 InChI=1S/C35H37N7O2/c1-24-5-3-4-6-31(24)35(17-18-35)34(44)38-32(33(43)37-28-15-19-41(2)20-16-28)21-29-23-42(40-39-29)30-13-11-27(12-14-30)26-9-7-25(22-36)8-10-26/h3-14,23,28,32H,15-21H2,1-2H3,(H,37,43)(H,38,44) QMUZXRGNTODESB-UHFFFAOYSA-N 50648187 CHEMBL5591180 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 150 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648187 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648187&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 172638559 519663589 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608071 CC(=O)N1CCC(NC(=O)C(Cc2cn(-c3ccc(-c4ccc(C#N)cc4)cc3)nn2)NC(=O)C2(c3ccccc3C)CC2)CC1 InChI=1S/C36H37N7O3/c1-24-5-3-4-6-32(24)36(17-18-36)35(46)39-33(34(45)38-29-15-19-42(20-16-29)25(2)44)21-30-23-43(41-40-30)31-13-11-28(12-14-31)27-9-7-26(22-37)8-10-27/h3-14,23,29,33H,15-21H2,1-2H3,(H,38,45)(H,39,46) QXTAQFWEVNZONP-UHFFFAOYSA-N 50648188 CHEMBL5597140 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Human 150 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648188 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648188&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 177379102 519663590 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608072 CC(C)(C)CN(C1CCS(=O)(=O)C1)C(=O)CCl InChI=1S/C11H20ClNO3S/c1-11(2,3)8-13(10(14)6-12)9-4-5-17(15,16)7-9/h9H,4-8H2,1-3H3 NMHVAHHYKGXBMY-UHFFFAOYSA-N 50618868 CHEMBL5397880 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Homo sapiens 17 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50618868 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50618868&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 155804394 505051846 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,9INN,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608073 c1ccc2c(c1)C(=NNC2=O)Cc3ccc(c(c3)C(=O)N4CCN(CC4)C(=O)C5CC5)F InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30) FDLYAMZZIXQODN-UHFFFAOYSA-N 27566 4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbonyl]-4-fluorophenyl}methyl)-1,2-dihydrophthalazin-1-one::Acylpiperazine analogue, 47::US9255106, AZD2281::Olaparib::US9187430, AZD-2281::US10174023, AZD2281::US10597399, Compound AZD2281 Poly [ADP-ribose] polymerase 1 Homo sapiens 5.0 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27566 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=232&target=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27566&enzyme=Poly+%5BADP-ribose%5D+polymerase+1&column=ki&startPg=0&Increment=50&submit=Search 09L 3U9Y,4TKG,4TVJ,5DS3,7AAD,7KK4,7KKO,8HLJ 23725625 57299275 1 MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW 9MJA,4OQB,4OQA,4OPX,4DQY,8G0H,7S6M,7S6H,5A00,4ZZZ,4XHU,6XVW,5HA9,4PJT,2RCW,1WOK,1UK1,1UK0,6I8T,6I8M,7S81,7S68,6M3I,9DMC,9BPY,8FZ1,8FYZ,8FYY,6NTU,6NRJ,6NRI,6NRH,6NRG,6NRF,6BHV,5DS3,8U4W,2N8A,2RIQ,2JVN,2CR9,2CS2,2L31,2L30,3ODE,3ODC,7SCZ,7SCY,3ODA,3OD8,2DMJ Poly [ADP-ribose] polymerase 1 PARP1_HUMAN P09874 B1ANJ4 Q8IUZ9 N/A A0A024R3T8 51608074 CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22) SHGAZHPCJJPHSC-UHFFFAOYSA-N 31883 ALL-TRANS-RETINOIC ACID::SMR000058245::cid_444795::[3H]RA::AT-RA::TRETINOIN::[3H]tretinoin::all-trans retinoic acid::CHEMBL38::Vitamin A acid::MLS000028588::[3H]Vitamin A acid::9-cis-retinoic acid (9cRA)::[3H]Retinoic acid::Atralin Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Homo sapiens 820 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31883 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31883&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 3KV 444795 85240509 CHEMBL38 C00777 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,9INN,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608075 CC(C)(C)c1ccc(cc1)S(=O)(=O)\N=C1/C=C(SCC(O)=O)C(=O)c2ccccc12 |t:16| InChI=1S/C22H21NO5S2/c1-22(2,3)14-8-10-15(11-9-14)30(27,28)23-18-12-19(29-13-20(24)25)21(26)17-7-5-4-6-16(17)18/h4-12H,13H2,1-3H3,(H,24,25) BXWWOKYIKNEEHJ-UHFFFAOYSA-N 50518736 CHEMBL4526940 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Homo sapiens 640 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518736 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518736&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 6022998 440727318 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,9INN,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75 51608076 OC(=O)[C@H](CCC(=O)N1CCOCC1)NC(=O)\C=C\c1ccc2ccccc2c1 |r| InChI=1S/C22H24N2O5/c25-20(9-6-16-5-7-17-3-1-2-4-18(17)15-16)23-19(22(27)28)8-10-21(26)24-11-13-29-14-12-24/h1-7,9,15,19H,8,10-14H2,(H,23,25)(H,27,28) YPETVRDSRIAFAE-UHFFFAOYSA-N 50518734 CHEMBL4467081 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Homo sapiens 1370 ChEMBL 10.7270/Q2P55T62 39229909 Liu, C; Chen, Z; Chen, T; Song, H; Shen, J; Yuan, X; Xia, S; Liu, Q; Chen, Q; Tian, Q; Meng, X; Han, Z; Dong, X; Yang, Y; Cai, L; Cheng, X; Jia, Y; Liu, G; Li, J; Ge, J; Dou, D //0 10/12/2025 Sichuan Kelun-Biotech Biopharmaceutical http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518734 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002453&target=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518734&enzyme=Peptidyl-prolyl+cis-trans+isomerase+NIMA-interacting+1&column=ki&startPg=0&Increment=50&submit=Search 155532089 440727316 1 MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 8SG2,7SUR,7SUQ,7SA5,1PIN,1NMV,8W11,8VZ5,8VZ3,1F8A,6O33,6VAJ,3KAF,3KAD,2XP6,2F21,1NMW,2RUC,9INN,2M8I,1I8H,1I8G,1I6C,2LB3,4GWV,4GWT,2KCF,5VTK,5VTJ,2N1O,5VTI,5B3Y,8C3C,8C2G,7OQA,7OQ9,7NRL,7NRK,7NJA,7NJ8,7NJ6,7NIG,7NIF,7BGW,7BGV,7BGR,7BGQ,7BG3,7BFW,7BDY,7BDT,7BDP,7AZ2,7AZ1,7AYF,7AXN,7AOG,5BMY Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1_HUMAN Q13526 A8K4V9 Q53X75