BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 51609452 C=CC(=O)N(Cc1ccc(OC)cc1)c1cccc(Cl)c1 InChI=1S/C17H16ClNO2/c1-3-17(20)19(15-6-4-5-14(18)11-15)12-13-7-9-16(21-2)10-8-13/h3-11H,1,12H2,2H3 SRRFNIXPZZEMDA-UHFFFAOYSA-N 50635693 CHEMBL5517789 Bcl-2-related protein A1 Human 23000 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50635693 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50635693&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177374250 519656096 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609453 C=CC(=O)N(Cc1ccc(OC)cc1)c1ccccc1Cl InChI=1S/C17H16ClNO2/c1-3-17(20)19(16-7-5-4-6-15(16)18)12-13-8-10-14(21-2)11-9-13/h3-11H,1,12H2,2H3 XDRNIXPBYXAPIY-UHFFFAOYSA-N 50648854 CHEMBL5613419 Bcl-2-related protein A1 Human 29000 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648854 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648854&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379529 519664256 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609454 C=CC(=O)N(Cc1ccc(OC)cc1)c1ccc(Cl)cc1 InChI=1S/C17H16ClNO2/c1-3-17(20)19(15-8-6-14(18)7-9-15)12-13-4-10-16(21-2)11-5-13/h3-11H,1,12H2,2H3 BDOKWZDINASMAH-UHFFFAOYSA-N 50648855 CHEMBL5613897 Bcl-2-related protein A1 Human 19000 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648855 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648855&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379530 519664257 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609455 C=CC(=O)N(Cc1ccc(OC)cc1)c1ccccc1 InChI=1S/C17H17NO2/c1-3-17(19)18(15-7-5-4-6-8-15)13-14-9-11-16(20-2)12-10-14/h3-12H,1,13H2,2H3 NWGKHKCGXCPGTR-UHFFFAOYSA-N 50648856 CHEMBL5612726 Bcl-2-related protein A1 Human >100000 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648856 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648856&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379531 519664258 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609456 C=CC(=O)N(Cc1ccc(Cl)cc1)c1ccc(OC)cc1 InChI=1S/C17H16ClNO2/c1-3-17(20)19(12-13-4-6-14(18)7-5-13)15-8-10-16(21-2)11-9-15/h3-11H,1,12H2,2H3 RQRGEOLKBRTALB-UHFFFAOYSA-N 50648857 CHEMBL5613623 Bcl-2-related protein A1 Human 9800 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648857 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648857&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379532 519664259 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609457 C=CC(=O)N(Cc1ccc(Cl)cc1)c1ccc(F)cc1 InChI=1S/C16H13ClFNO/c1-2-16(20)19(15-9-7-14(18)8-10-15)11-12-3-5-13(17)6-4-12/h2-10H,1,11H2 JSNIWFWYEFQRGS-UHFFFAOYSA-N 50648858 CHEMBL5612442 Bcl-2-related protein A1 Human 5100 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648858 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648858&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search A1IDG 9FL0 177379533 519664260 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609458 C=CC(=O)N(Cc1ccc(Cl)cc1)c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1 InChI=1S/C21H23ClN2O2/c1-2-21(25)24(14-15-3-5-16(22)6-4-15)18-8-11-19(12-9-18)26-20-10-7-17(23)13-20/h2-6,8-9,11-12,17,20H,1,7,10,13-14,23H2 RCIGCKKIWRZXFW-UHFFFAOYSA-N 50648859 CHEMBL5612066 Bcl-2-related protein A1 Human 450 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648859 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648859&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search A1IDO 9FKZ 177379534 519664261 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609459 C=CC(=O)N(Cc1ccc(Cl)cc1)c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1 InChI=1S/C21H23ClN2O2/c1-2-21(25)24(14-15-3-5-16(22)6-4-15)18-8-11-19(12-9-18)26-20-10-7-17(23)13-20/h2-6,8-9,11-12,17,20H,1,7,10,13-14,23H2 RCIGCKKIWRZXFW-UHFFFAOYSA-N 50648859 CHEMBL5612066 Bcl-2-related protein A1 Human 340 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648859 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648859&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search A1IDO 9FKZ 177379534 519664261 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609460 C=CC(=O)N(Cc1ccc(Cl)cc1)c1ccc(O[C@H]2CC[C@H](N)C2)cc1 InChI=1S/C21H23ClN2O2/c1-2-21(25)24(14-15-3-5-16(22)6-4-15)18-8-11-19(12-9-18)26-20-10-7-17(23)13-20/h2-6,8-9,11-12,17,20H,1,7,10,13-14,23H2 RCIGCKKIWRZXFW-UHFFFAOYSA-N 50648860 CHEMBL5613858 Bcl-2-related protein A1 Human 5100 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648860 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648860&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379535 519664262 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609461 C=CC(=O)N(Cc1ccc(Cl)cc1)c1ccc(O[C@H]2CC[C@@H](N)C2)cc1 InChI=1S/C21H23ClN2O2/c1-2-21(25)24(14-15-3-5-16(22)6-4-15)18-8-11-19(12-9-18)26-20-10-7-17(23)13-20/h2-6,8-9,11-12,17,20H,1,7,10,13-14,23H2 RCIGCKKIWRZXFW-UHFFFAOYSA-N 50648861 CHEMBL5614214 Bcl-2-related protein A1 Human 42000 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648861 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648861&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379536 519664263 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609462 C=CC(=O)N(Cc1ccc(Cl)cc1)c1ccc(O[C@@H]2CC[C@@H](NC)C2)cc1 InChI=1S/C22H25ClN2O2/c1-3-22(26)25(15-16-4-6-17(23)7-5-16)19-9-12-20(13-10-19)27-21-11-8-18(14-21)24-2/h3-7,9-10,12-13,18,21,24H,1,8,11,14-15H2,2H3 OPBPBSIMULDSLA-UHFFFAOYSA-N 50648862 CHEMBL5613581 Bcl-2-related protein A1 Human 380 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648862 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648862&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379537 519664264 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609463 C=CC(=O)N(Cc1ccc(Cl)cc1)c1ccc(O[C@@H]2CC[C@@H](N(C)C)C2)cc1 InChI=1S/C23H27ClN2O2/c1-4-23(27)26(16-17-5-7-18(24)8-6-17)19-9-12-21(13-10-19)28-22-14-11-20(15-22)25(2)3/h4-10,12-13,20,22H,1,11,14-16H2,2-3H3 VNUBPMMZIOHFOG-UHFFFAOYSA-N 50648863 CHEMBL5614022 Bcl-2-related protein A1 Human 440 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648863 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648863&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379538 519664265 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609464 C=CC(=O)N(Cc1ccc(Cl)cc1)c1ccc(O[C@@H]2CC[C@@H](NC(C)=O)C2)cc1 InChI=1S/C23H25ClN2O3/c1-3-23(28)26(15-17-4-6-18(24)7-5-17)20-9-12-21(13-10-20)29-22-11-8-19(14-22)25-16(2)27/h3-7,9-10,12-13,19,22H,1,8,11,14-15H2,2H3,(H,25,27) QPFKVPNFCOWVQO-UHFFFAOYSA-N 50648864 CHEMBL5612546 Bcl-2-related protein A1 Human 460 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648864 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648864&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379539 519664266 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609465 C=CC(=O)N(Cc1ccc(Cl)cc1)c1ccc(O[C@@H]2CC[C@@H](N(C)C(C)=O)C2)cc1 InChI=1S/C24H27ClN2O3/c1-4-24(29)27(16-18-5-7-19(25)8-6-18)20-9-12-22(13-10-20)30-23-14-11-21(15-23)26(3)17(2)28/h4-10,12-13,21,23H,1,11,14-16H2,2-3H3 SRTSFBQBNGUUGD-UHFFFAOYSA-N 50648865 CHEMBL5614038 Bcl-2-related protein A1 Human 22000 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648865 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648865&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379540 519664267 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609466 C=CC(=O)N(Cc1ccc(Cl)cc1)c1ccc(O[C@@H]2CC[C@@H](NC(=O)NC)C2)cc1 InChI=1S/C23H26ClN3O3/c1-3-22(28)27(15-16-4-6-17(24)7-5-16)19-9-12-20(13-10-19)30-21-11-8-18(14-21)26-23(29)25-2/h3-7,9-10,12-13,18,21H,1,8,11,14-15H2,2H3,(H2,25,26,29) INWBKDYXEKNFQQ-UHFFFAOYSA-N 50648866 CHEMBL5612663 Bcl-2-related protein A1 Human 360 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648866 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648866&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379541 519664268 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609467 C=CC(=O)N(Cc1ccc(C(F)(F)F)cc1)c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1 InChI=1S/C22H23F3N2O2/c1-2-21(28)27(14-15-3-5-16(6-4-15)22(23,24)25)18-8-11-19(12-9-18)29-20-10-7-17(26)13-20/h2-6,8-9,11-12,17,20H,1,7,10,13-14,26H2 XTCLEDKBYUJACP-UHFFFAOYSA-N 50648867 CHEMBL5614064 Bcl-2-related protein A1 Human 720 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648867 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648867&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379542 519664269 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609468 C=CC(=O)N(Cc1ccc(Cl)c(C#N)c1)c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1 InChI=1S/C22H22ClN3O2/c1-2-22(27)26(14-15-3-10-21(23)16(11-15)13-24)18-5-8-19(9-6-18)28-20-7-4-17(25)12-20/h2-3,5-6,8-11,17,20H,1,4,7,12,14,25H2 DVAMTFVOOFYMOP-UHFFFAOYSA-N 50648868 CHEMBL5612634 Bcl-2-related protein A1 Human 350 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648868 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648868&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379543 519664270 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609469 C=CC(=O)N(Cc1ccc(C(F)(F)F)c(C#N)c1)c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1 InChI=1S/C23H22F3N3O2/c1-2-22(30)29(14-15-3-10-21(23(24,25)26)16(11-15)13-27)18-5-8-19(9-6-18)31-20-7-4-17(28)12-20/h2-3,5-6,8-11,17,20H,1,4,7,12,14,28H2 PTRAVKRZRZUTQE-UHFFFAOYSA-N 50648869 CHEMBL5613029 Bcl-2-related protein A1 Human 300 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648869 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648869&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379544 519664271 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609470 C=CC(=O)N(Cc1ccc(C#N)c(Cl)c1)c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1 InChI=1S/C22H22ClN3O2/c1-2-22(27)26(14-15-3-4-16(13-24)21(23)11-15)18-6-9-19(10-7-18)28-20-8-5-17(25)12-20/h2-4,6-7,9-11,17,20H,1,5,8,12,14,25H2 HTONNMPIPBVBQK-UHFFFAOYSA-N 50648870 CHEMBL5612215 Bcl-2-related protein A1 Human 550 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648870 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648870&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379545 519664272 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609471 C=CC(=O)N(c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1)[C@H](C)c1ccc(Cl)cc1 InChI=1S/C22H25ClN2O2/c1-3-22(26)25(15(2)16-4-6-17(23)7-5-16)19-9-12-20(13-10-19)27-21-11-8-18(24)14-21/h3-7,9-10,12-13,15,18,21H,1,8,11,14,24H2,2H3 UDCTXXDDIJLFNU-UHFFFAOYSA-N 50648871 CHEMBL5613717 Bcl-2-related protein A1 Human 2700 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648871 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648871&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379546 519664273 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609472 C=CC(=O)N(c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1)[C@@H](C)c1ccc(Cl)cc1 InChI=1S/C22H25ClN2O2/c1-3-22(26)25(15(2)16-4-6-17(23)7-5-16)19-9-12-20(13-10-19)27-21-11-8-18(24)14-21/h3-7,9-10,12-13,15,18,21H,1,8,11,14,24H2,2H3 UDCTXXDDIJLFNU-UHFFFAOYSA-N 50648872 CHEMBL5613621 Bcl-2-related protein A1 Human 63 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648872 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648872&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379547 519664274 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609473 C=CC(=O)N(c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1)[C@H](C)c1ccc(C(F)(F)F)c(C#N)c1 InChI=1S/C24H24F3N3O2/c1-3-23(31)30(15(2)16-4-11-22(24(25,26)27)17(12-16)14-28)19-6-9-20(10-7-19)32-21-8-5-18(29)13-21/h3-4,6-7,9-12,15,18,21H,1,5,8,13,29H2,2H3 XUNQZBSJKCTTNE-UHFFFAOYSA-N 50648873 CHEMBL5613885 Bcl-2-related protein A1 Human 1600 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648873 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648873&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379548 519664275 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609474 C=CC(=O)N(c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1)[C@@H](C)c1ccc(C(F)(F)F)c(C#N)c1 InChI=1S/C24H24F3N3O2/c1-3-23(31)30(15(2)16-4-11-22(24(25,26)27)17(12-16)14-28)19-6-9-20(10-7-19)32-21-8-5-18(29)13-21/h3-4,6-7,9-12,15,18,21H,1,5,8,13,29H2,2H3 XUNQZBSJKCTTNE-UHFFFAOYSA-N 50648874 CHEMBL5613766 Bcl-2-related protein A1 Human 22 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648874 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648874&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379549 519664276 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609475 C=CC(=O)N(Cc1ccc(Cl)cc1)c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1 InChI=1S/C21H23ClN2O2/c1-2-21(25)24(14-15-3-5-16(22)6-4-15)18-8-11-19(12-9-18)26-20-10-7-17(23)13-20/h2-6,8-9,11-12,17,20H,1,7,10,13-14,23H2 RCIGCKKIWRZXFW-UHFFFAOYSA-N 50648859 CHEMBL5612066 Bcl-2-related protein A1 Human 7400 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648859 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648859&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search A1IDO 9FKZ 177379534 519664261 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609476 C=CC(=O)N(Cc1ccc(C(F)(F)F)cc1)c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1 InChI=1S/C22H23F3N2O2/c1-2-21(28)27(14-15-3-5-16(6-4-15)22(23,24)25)18-8-11-19(12-9-18)29-20-10-7-17(26)13-20/h2-6,8-9,11-12,17,20H,1,7,10,13-14,26H2 XTCLEDKBYUJACP-UHFFFAOYSA-N 50648867 CHEMBL5614064 Bcl-2-related protein A1 Human 2600 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648867 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648867&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379542 519664269 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609477 C=CC(=O)N(Cc1ccc(Cl)c(C#N)c1)c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1 InChI=1S/C22H22ClN3O2/c1-2-22(27)26(14-15-3-10-21(23)16(11-15)13-24)18-5-8-19(9-6-18)28-20-7-4-17(25)12-20/h2-3,5-6,8-11,17,20H,1,4,7,12,14,25H2 DVAMTFVOOFYMOP-UHFFFAOYSA-N 50648868 CHEMBL5612634 Bcl-2-related protein A1 Human 3700 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648868 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648868&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379543 519664270 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609478 C=CC(=O)N(Cc1ccc(C(F)(F)F)c(C#N)c1)c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1 InChI=1S/C23H22F3N3O2/c1-2-22(30)29(14-15-3-10-21(23(24,25)26)16(11-15)13-27)18-5-8-19(9-6-18)31-20-7-4-17(28)12-20/h2-3,5-6,8-11,17,20H,1,4,7,12,14,28H2 PTRAVKRZRZUTQE-UHFFFAOYSA-N 50648869 CHEMBL5613029 Bcl-2-related protein A1 Human 1800 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648869 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648869&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379544 519664271 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609479 C=CC(=O)N(c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1)[C@H](C)c1ccc(Cl)cc1 InChI=1S/C22H25ClN2O2/c1-3-22(26)25(15(2)16-4-6-17(23)7-5-16)19-9-12-20(13-10-19)27-21-11-8-18(24)14-21/h3-7,9-10,12-13,15,18,21H,1,8,11,14,24H2,2H3 UDCTXXDDIJLFNU-UHFFFAOYSA-N 50648871 CHEMBL5613717 Bcl-2-related protein A1 Human 11000 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648871 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648871&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379546 519664273 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609480 C=CC(=O)N(c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1)[C@@H](C)c1ccc(Cl)cc1 InChI=1S/C22H25ClN2O2/c1-3-22(26)25(15(2)16-4-6-17(23)7-5-16)19-9-12-20(13-10-19)27-21-11-8-18(24)14-21/h3-7,9-10,12-13,15,18,21H,1,8,11,14,24H2,2H3 UDCTXXDDIJLFNU-UHFFFAOYSA-N 50648872 CHEMBL5613621 Bcl-2-related protein A1 Human 1600 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648872 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648872&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379547 519664274 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609481 C=CC(=O)N(c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1)[C@H](C)c1ccc(C(F)(F)F)c(C#N)c1 InChI=1S/C24H24F3N3O2/c1-3-23(31)30(15(2)16-4-11-22(24(25,26)27)17(12-16)14-28)19-6-9-20(10-7-19)32-21-8-5-18(29)13-21/h3-4,6-7,9-12,15,18,21H,1,5,8,13,29H2,2H3 XUNQZBSJKCTTNE-UHFFFAOYSA-N 50648873 CHEMBL5613885 Bcl-2-related protein A1 Human 6900 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648873 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648873&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379548 519664275 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609482 C=CC(=O)N(c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1)[C@@H](C)c1ccc(C(F)(F)F)c(C#N)c1 InChI=1S/C24H24F3N3O2/c1-3-23(31)30(15(2)16-4-11-22(24(25,26)27)17(12-16)14-28)19-6-9-20(10-7-19)32-21-8-5-18(29)13-21/h3-4,6-7,9-12,15,18,21H,1,5,8,13,29H2,2H3 XUNQZBSJKCTTNE-UHFFFAOYSA-N 50648874 CHEMBL5613766 Bcl-2-related protein A1 Human 370 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648874 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3930&target=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648874&enzyme=Bcl-2-related+protein+A1&column=ki&startPg=0&Increment=50&submit=Search 177379549 519664276 1 MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC 4ZEQ,3MQP,3I1H,9GIT,9GIS,9GIR,9GIQ,9GIP,9FL0,9FKZ,9FKY,9EW8,8RPO,6MBC,6MBB,6E3J,6E3I,5UUP,5UUL,5UUK,6RJP,2VM6 Bcl-2-related protein A1 B2LA1_HUMAN Q16548 Q6FGZ4 Q6FH19 Q86W13 Q99524 51609483 C=CC(=O)N(c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1)[C@@H](C)c1ccc(C(F)(F)F)c(C#N)c1 InChI=1S/C24H24F3N3O2/c1-3-23(31)30(15(2)16-4-11-22(24(25,26)27)17(12-16)14-28)19-6-9-20(10-7-19)32-21-8-5-18(29)13-21/h3-4,6-7,9-12,15,18,21H,1,5,8,13,29H2,2H3 XUNQZBSJKCTTNE-UHFFFAOYSA-N 50648874 CHEMBL5613766 Bcl-2-like protein 1 Human >30000 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648874 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3744&target=Bcl-2-like+protein+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648874&enzyme=Bcl-2-like+protein+1&column=ki&startPg=0&Increment=50&submit=Search 177379549 519664276 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK 8FY0,2B48,1R2D,7CA4,4HNJ,2MEJ,2ME9,2ME8,3IIH,3IHC,1PQ1,1PQ0,1AF3,3R85,7JGW,7JGV,6UVH,6UVG,6UVF,6UVE,6UVD,6UVC,5VX3,5FMJ,4TUH,4CIN,4C5D,4C52,4A1W,4A1U,3ZLR,3IO8,3INQ,3FDM,3FDL,2YQ7,2YQ6,2YJ1,6DCO,6DCN,8ZEB,6HJL,7Y8D,6X7I Bcl-2-like protein 1 B2CL1_HUMAN Q07817 E1P5L6 Q5CZ89 Q5TE65 Q92976 51609484 C=CC(=O)N(c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1)[C@@H](C)c1ccc(C(F)(F)F)c(C#N)c1 InChI=1S/C24H24F3N3O2/c1-3-23(31)30(15(2)16-4-11-22(24(25,26)27)17(12-16)14-28)19-6-9-20(10-7-19)32-21-8-5-18(29)13-21/h3-4,6-7,9-12,15,18,21H,1,5,8,13,29H2,2H3 XUNQZBSJKCTTNE-UHFFFAOYSA-N 50648874 CHEMBL5613766 Apoptosis regulator Bcl-2 Human >30000 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648874 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=508&target=Apoptosis+regulator+Bcl-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648874&enzyme=Apoptosis+regulator+Bcl-2&column=ki&startPg=0&Increment=50&submit=Search 177379549 519664276 1 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK 8FY1,2XA0,5JSN Apoptosis regulator Bcl-2 BCL2_HUMAN P10415 C9JHD5 P10416 Q13842 Q16197 51609485 C=CC(=O)N(c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1)[C@@H](C)c1ccc(C(F)(F)F)c(C#N)c1 InChI=1S/C24H24F3N3O2/c1-3-23(31)30(15(2)16-4-11-22(24(25,26)27)17(12-16)14-28)19-6-9-20(10-7-19)32-21-8-5-18(29)13-21/h3-4,6-7,9-12,15,18,21H,1,5,8,13,29H2,2H3 XUNQZBSJKCTTNE-UHFFFAOYSA-N 50648874 CHEMBL5613766 Induced myeloid leukemia cell differentiation protein Mcl-1 Human >100000 ChEMBL 10.7270/Q2251PW8 39291659 Lucas, SCC; Blackwell, JH; Börjesson, U; Hargreaves, D; Milbradt, AG; Bostock, MJ; Ahmed, S; Beaumont, K; Cheung, T; Demanze, S; Gohlke, A; Guerot, C; Haider, A; Kantae, V; Kauffman, GW; Kinzel, O; Kupcova, L; Lainchbury, MD; Lamb, ML; Leon, L; Palisse, A; Sacchetto, C; Storer, RI; Su, N; Thomson, C; Vales, J; Chen, Y; Hu, X //0 10/12/2025 AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50648874 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3929&target=Induced+myeloid+leukemia+cell+differentiation+protein+Mcl-1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50648874&enzyme=Induced+myeloid+leukemia+cell+differentiation+protein+Mcl-1&column=ki&startPg=0&Increment=50&submit=Search 177379549 519664276 1 MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR 5JSB,2KBW,6NE5,8Y1Z,8Y1Y,8IQM,6UDY,6UDX,6UDV,6UDU,6UDT,6UDI,6UD2,6OQN,6OQD,6OQC,6OQB,5C6H,7NB7,7NB4,6YBG,6QZB,6QZ8,6QZ6,6QZ5,6QYP,6QFQ,6QFI,6P3P,6O6G,6O4U,6O6F,3MK8,3KZ0,3KJ2,3KJ1,3KJ0,2PQK,4ZBI,4ZBF,4HW4,6ZIE,3WIY,3WIX,6STJ,5C3F,6UAB,6UA3,5UUM,6U6F,6U67,6U65,6U63,6MBD,3PK1,9EFJ,9UGP,9CKN,8VJP,6VBX,4HW3,4HW2,9PW6,6MBE,9CDT,8H7B,8X62,6U64,7XGE,5W89,5W8F,5FDO,4WMR,6FS1,9PW7,4G35 Induced myeloid leukemia cell differentiation protein Mcl-1 MCL1_HUMAN Q07820 B2R6B2 D3DV03 D3DV04 Q9HD91 Q9NRQ3 Q9NRQ4 Q9UHR7 Q9UHR8 Q9UHR9 Q9UNJ1