BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
120444	C=CC(=O)Nc5ccc(c3c(c2ccc(Oc1nccc(C)n1)cc2)c(C(N)=O)c4cnccn34)cc5	InChI=1S/C28H22N6O3/c1-3-23(35)33-20-8-4-19(5-9-20)26-24(25(27(29)36)22-16-30-14-15-34(22)26)18-6-10-21(11-7-18)37-28-31-13-12-17(2)32-28/h3-16H,1H2,2H3,(H2,29,36)(H,33,35)	KRGYOKDESCSWCU-UHFFFAOYSA-N	73147	6-(4-acrylamidophenyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 1	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=73147	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=73147&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			24982907	252650393							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120445	C=CC(=O)Nc5ccc(c3c(c2ccc(Oc1nccc(C)n1)cc2)c(C(N)=O)c4cnccn34)cc5	InChI=1S/C28H22N6O3/c1-3-23(35)33-20-8-4-19(5-9-20)26-24(25(27(29)36)22-16-30-14-15-34(22)26)18-6-10-21(11-7-18)37-28-31-13-12-17(2)32-28/h3-16H,1H2,2H3,(H2,29,36)(H,33,35)	KRGYOKDESCSWCU-UHFFFAOYSA-N	73147	6-(4-acrylamidophenyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 1	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=73147	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=73147&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			24982907	252650393							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120446	C=CC(=O)Nc5ccc(c3c(c2ccc(Oc1nccc(C)n1)cc2)c(C(N)=O)c4cnccn34)cc5	InChI=1S/C28H22N6O3/c1-3-23(35)33-20-8-4-19(5-9-20)26-24(25(27(29)36)22-16-30-14-15-34(22)26)18-6-10-21(11-7-18)37-28-31-13-12-17(2)32-28/h3-16H,1H2,2H3,(H2,29,36)(H,33,35)	KRGYOKDESCSWCU-UHFFFAOYSA-N	73147	6-(4-acrylamidophenyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 1	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=73147	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=73147&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			24982907	252650393							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120447	C=CC(=O)Nc5ccc(c3c(c2ccc(Oc1nccc(C)n1)cc2)c(C(N)=O)c4cnccn34)cc5	InChI=1S/C28H22N6O3/c1-3-23(35)33-20-8-4-19(5-9-20)26-24(25(27(29)36)22-16-30-14-15-34(22)26)18-6-10-21(11-7-18)37-28-31-13-12-17(2)32-28/h3-16H,1H2,2H3,(H2,29,36)(H,33,35)	KRGYOKDESCSWCU-UHFFFAOYSA-N	73147	6-(4-acrylamidophenyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 1	Fibroblast growth factor receptor 4	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=73147	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6750&target=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=73147&enzyme=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search			24982907	252650393							1	MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT	6IUP,6IUO,6YI8,4TYJ,4TYI,4TYG,4TYE,5NWZ,5NUD,7VJL,8W5C,7YSW	Fibroblast growth factor receptor 4	FGFR4_HUMAN	P22455	G3JVM2 G3JVM5 G3JVM7 G3JVM9 O43785 Q14309 Q71TW8 Q8TDA0 Q96KE5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120448	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H22N6O3/c1-3-23(35)33-20-8-4-19(5-9-20)26-24(25(27(29)36)22-16-30-14-15-34(22)26)18-6-10-21(11-7-18)37-28-31-13-12-17(2)32-28/h3-16H,1H2,2H3,(H2,29,36)(H,33,35)	KRGYOKDESCSWCU-UHFFFAOYSA-N	75445	6-(4-acrylamidophenyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 2	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75445&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			646999	252652653							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120449	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H22N6O3/c1-3-23(35)33-20-8-4-19(5-9-20)26-24(25(27(29)36)22-16-30-14-15-34(22)26)18-6-10-21(11-7-18)37-28-31-13-12-17(2)32-28/h3-16H,1H2,2H3,(H2,29,36)(H,33,35)	KRGYOKDESCSWCU-UHFFFAOYSA-N	75445	6-(4-acrylamidophenyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 2	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75445&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			646999	252652653							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120450	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H22N6O3/c1-3-23(35)33-20-8-4-19(5-9-20)26-24(25(27(29)36)22-16-30-14-15-34(22)26)18-6-10-21(11-7-18)37-28-31-13-12-17(2)32-28/h3-16H,1H2,2H3,(H2,29,36)(H,33,35)	KRGYOKDESCSWCU-UHFFFAOYSA-N	75445	6-(4-acrylamidophenyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 2	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75445&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			646999	252652653							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120451	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H22N6O3/c1-3-23(35)33-20-8-4-19(5-9-20)26-24(25(27(29)36)22-16-30-14-15-34(22)26)18-6-10-21(11-7-18)37-28-31-13-12-17(2)32-28/h3-16H,1H2,2H3,(H2,29,36)(H,33,35)	KRGYOKDESCSWCU-UHFFFAOYSA-N	75445	6-(4-acrylamidophenyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 2	Fibroblast growth factor receptor 4	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6750&target=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75445&enzyme=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search			646999	252652653							1	MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT	6IUP,6IUO,6YI8,4TYJ,4TYI,4TYG,4TYE,5NWZ,5NUD,7VJL,8W5C,7YSW	Fibroblast growth factor receptor 4	FGFR4_HUMAN	P22455	G3JVM2 G3JVM5 G3JVM7 G3JVM9 O43785 Q14309 Q71TW8 Q8TDA0 Q96KE5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120452	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnccn23)cn1	InChI=1S/C28H22N6O3/c1-3-23(35)33-22-12-9-19(15-31-22)27-25(26(28(29)36)21-16-30-13-14-34(21)27)18-7-10-20(11-8-18)37-24-6-4-5-17(2)32-24/h3-16H,1H2,2H3,(H2,29,36)(H,31,33,35)	CYGXJXMKSYWUKC-UHFFFAOYSA-N	75446	6-(6-acrylamidopyridin-3-yl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 3	Fibroblast growth factor receptor 1	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75446&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			649189	252652654							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120453	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnccn23)cn1	InChI=1S/C28H22N6O3/c1-3-23(35)33-22-12-9-19(15-31-22)27-25(26(28(29)36)21-16-30-13-14-34(21)27)18-7-10-20(11-8-18)37-24-6-4-5-17(2)32-24/h3-16H,1H2,2H3,(H2,29,36)(H,31,33,35)	CYGXJXMKSYWUKC-UHFFFAOYSA-N	75446	6-(6-acrylamidopyridin-3-yl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 3	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75446&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			649189	252652654							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120454	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnccn23)cn1	InChI=1S/C28H22N6O3/c1-3-23(35)33-22-12-9-19(15-31-22)27-25(26(28(29)36)21-16-30-13-14-34(21)27)18-7-10-20(11-8-18)37-24-6-4-5-17(2)32-24/h3-16H,1H2,2H3,(H2,29,36)(H,31,33,35)	CYGXJXMKSYWUKC-UHFFFAOYSA-N	75446	6-(6-acrylamidopyridin-3-yl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 3	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75446&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			649189	252652654							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120455	C=CC(=O)Nc1cc(C)c(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnccn23)cn1	InChI=1S/C29H24N6O3/c1-4-24(36)34-23-14-17(2)21(15-32-23)28-26(27(29(30)37)22-16-31-12-13-35(22)28)19-8-10-20(11-9-19)38-25-7-5-6-18(3)33-25/h4-16H,1H2,2-3H3,(H2,30,37)(H,32,34,36)	RZWCLLFZTGMPDW-UHFFFAOYSA-N	75447	6-(6-acrylamido-4-methylpyridin-3-yl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 4	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75447&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			649937	252652655							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120456	C=CC(=O)Nc1cc(C)c(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnccn23)cn1	InChI=1S/C29H24N6O3/c1-4-24(36)34-23-14-17(2)21(15-32-23)28-26(27(29(30)37)22-16-31-12-13-35(22)28)19-8-10-20(11-9-19)38-25-7-5-6-18(3)33-25/h4-16H,1H2,2-3H3,(H2,30,37)(H,32,34,36)	RZWCLLFZTGMPDW-UHFFFAOYSA-N	75447	6-(6-acrylamido-4-methylpyridin-3-yl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 4	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75447&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			649937	252652655							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120457	C=CC(=O)Nc1cc(C)c(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnccn23)cn1	InChI=1S/C29H24N6O3/c1-4-24(36)34-23-14-17(2)21(15-32-23)28-26(27(29(30)37)22-16-31-12-13-35(22)28)19-8-10-20(11-9-19)38-25-7-5-6-18(3)33-25/h4-16H,1H2,2-3H3,(H2,30,37)(H,32,34,36)	RZWCLLFZTGMPDW-UHFFFAOYSA-N	75447	6-(6-acrylamido-4-methylpyridin-3-yl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 4	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75447&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			649937	252652655							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120458	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cncc(C)n23)cc1	InChI=1S/C30H25N5O3/c1-4-25(36)34-22-12-8-21(9-13-22)29-27(28(30(31)37)24-17-32-16-19(3)35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	WCMLPZLIXFHGJH-UHFFFAOYSA-N	75448	tert-butyl 2-cyano-2-(6-methylpyrazin-2-yl)acetate (Intermediate 5.1)::6-(4-acrylamidophenyl)-4-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 5	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75448&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2737129	252652656							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120459	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cncc(C)n23)cc1	InChI=1S/C30H25N5O3/c1-4-25(36)34-22-12-8-21(9-13-22)29-27(28(30(31)37)24-17-32-16-19(3)35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	WCMLPZLIXFHGJH-UHFFFAOYSA-N	75448	tert-butyl 2-cyano-2-(6-methylpyrazin-2-yl)acetate (Intermediate 5.1)::6-(4-acrylamidophenyl)-4-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 5	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75448&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2737129	252652656							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120460	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cncc(C)n23)cc1	InChI=1S/C30H25N5O3/c1-4-25(36)34-22-12-8-21(9-13-22)29-27(28(30(31)37)24-17-32-16-19(3)35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	WCMLPZLIXFHGJH-UHFFFAOYSA-N	75448	tert-butyl 2-cyano-2-(6-methylpyrazin-2-yl)acetate (Intermediate 5.1)::6-(4-acrylamidophenyl)-4-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 5	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75448&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2737129	252652656							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120461	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cncc(C)n23)cc1	InChI=1S/C30H25N5O3/c1-4-25(36)34-22-12-8-21(9-13-22)29-27(28(30(31)37)24-17-32-16-19(3)35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	WCMLPZLIXFHGJH-UHFFFAOYSA-N	75448	tert-butyl 2-cyano-2-(6-methylpyrazin-2-yl)acetate (Intermediate 5.1)::6-(4-acrylamidophenyl)-4-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 5	Fibroblast growth factor receptor 4	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6750&target=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75448&enzyme=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search			2737129	252652656							1	MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT	6IUP,6IUO,6YI8,4TYJ,4TYI,4TYG,4TYE,5NWZ,5NUD,7VJL,8W5C,7YSW	Fibroblast growth factor receptor 4	FGFR4_HUMAN	P22455	G3JVM2 G3JVM5 G3JVM7 G3JVM9 O43785 Q14309 Q71TW8 Q8TDA0 Q96KE5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120462	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cncc(C)n23)cc1	InChI=1S/C29H24N6O3/c1-4-24(36)34-21-9-5-20(6-10-21)27-25(26(28(30)37)23-16-31-15-18(3)35(23)27)19-7-11-22(12-8-19)38-29-32-14-13-17(2)33-29/h4-16H,1H2,2-3H3,(H2,30,37)(H,34,36)	ZYPZTXUDFKPFDZ-UHFFFAOYSA-N	75449	Intermediate 6.2::6-(4-acrylamidophenyl)-4-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 6	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75449&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			665305	252652657							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120463	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cncc(C)n23)cc1	InChI=1S/C29H24N6O3/c1-4-24(36)34-21-9-5-20(6-10-21)27-25(26(28(30)37)23-16-31-15-18(3)35(23)27)19-7-11-22(12-8-19)38-29-32-14-13-17(2)33-29/h4-16H,1H2,2-3H3,(H2,30,37)(H,34,36)	ZYPZTXUDFKPFDZ-UHFFFAOYSA-N	75449	Intermediate 6.2::6-(4-acrylamidophenyl)-4-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 6	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75449&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			665305	252652657							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120464	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cncc(C)n23)cc1	InChI=1S/C29H24N6O3/c1-4-24(36)34-21-9-5-20(6-10-21)27-25(26(28(30)37)23-16-31-15-18(3)35(23)27)19-7-11-22(12-8-19)38-29-32-14-13-17(2)33-29/h4-16H,1H2,2-3H3,(H2,30,37)(H,34,36)	ZYPZTXUDFKPFDZ-UHFFFAOYSA-N	75449	Intermediate 6.2::6-(4-acrylamidophenyl)-4-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 6	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75449&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			665305	252652657							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120465	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cncc(C)n23)cc1	InChI=1S/C29H24N6O3/c1-4-24(36)34-21-9-5-20(6-10-21)27-25(26(28(30)37)23-16-31-15-18(3)35(23)27)19-7-11-22(12-8-19)38-29-32-14-13-17(2)33-29/h4-16H,1H2,2-3H3,(H2,30,37)(H,34,36)	ZYPZTXUDFKPFDZ-UHFFFAOYSA-N	75449	Intermediate 6.2::6-(4-acrylamidophenyl)-4-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 6	Fibroblast growth factor receptor 4	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6750&target=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75449&enzyme=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search			665305	252652657							1	MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT	6IUP,6IUO,6YI8,4TYJ,4TYI,4TYG,4TYE,5NWZ,5NUD,7VJL,8W5C,7YSW	Fibroblast growth factor receptor 4	FGFR4_HUMAN	P22455	G3JVM2 G3JVM5 G3JVM7 G3JVM9 O43785 Q14309 Q71TW8 Q8TDA0 Q96KE5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120466	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H25N5O3/c1-4-25(36)34-22-12-8-21(9-13-22)29-27(28(30(31)37)24-16-32-19(3)17-35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	FRHAPUIMVIBHGQ-UHFFFAOYSA-N	75451	6-(4-acrylamidophenyl)-3-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 7	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75451	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75451&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			665842	252652659							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120467	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H25N5O3/c1-4-25(36)34-22-12-8-21(9-13-22)29-27(28(30(31)37)24-16-32-19(3)17-35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	FRHAPUIMVIBHGQ-UHFFFAOYSA-N	75451	6-(4-acrylamidophenyl)-3-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 7	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75451	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75451&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			665842	252652659							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120468	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H25N5O3/c1-4-25(36)34-22-12-8-21(9-13-22)29-27(28(30(31)37)24-16-32-19(3)17-35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	FRHAPUIMVIBHGQ-UHFFFAOYSA-N	75451	6-(4-acrylamidophenyl)-3-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 7	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75451	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75451&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			665842	252652659							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120469	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H25N5O3/c1-4-25(36)34-22-12-8-21(9-13-22)29-27(28(30(31)37)24-16-32-19(3)17-35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	FRHAPUIMVIBHGQ-UHFFFAOYSA-N	75451	6-(4-acrylamidophenyl)-3-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 7	Fibroblast growth factor receptor 4	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75451	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6750&target=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75451&enzyme=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search			665842	252652659							1	MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT	6IUP,6IUO,6YI8,4TYJ,4TYI,4TYG,4TYE,5NWZ,5NUD,7VJL,8W5C,7YSW	Fibroblast growth factor receptor 4	FGFR4_HUMAN	P22455	G3JVM2 G3JVM5 G3JVM7 G3JVM9 O43785 Q14309 Q71TW8 Q8TDA0 Q96KE5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120470	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H24N6O3/c1-4-24(36)34-21-9-5-20(6-10-21)27-25(26(28(30)37)23-15-32-18(3)16-35(23)27)19-7-11-22(12-8-19)38-29-31-14-13-17(2)33-29/h4-16H,1H2,2-3H3,(H2,30,37)(H,34,36)	CBCBXZCFWNODDR-UHFFFAOYSA-N	75453	6-(4-acrylamidophenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 8	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75453	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75453&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			674827	252652661							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120471	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H24N6O3/c1-4-24(36)34-21-9-5-20(6-10-21)27-25(26(28(30)37)23-15-32-18(3)16-35(23)27)19-7-11-22(12-8-19)38-29-31-14-13-17(2)33-29/h4-16H,1H2,2-3H3,(H2,30,37)(H,34,36)	CBCBXZCFWNODDR-UHFFFAOYSA-N	75453	6-(4-acrylamidophenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 8	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75453	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75453&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			674827	252652661							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120472	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H24N6O3/c1-4-24(36)34-21-9-5-20(6-10-21)27-25(26(28(30)37)23-15-32-18(3)16-35(23)27)19-7-11-22(12-8-19)38-29-31-14-13-17(2)33-29/h4-16H,1H2,2-3H3,(H2,30,37)(H,34,36)	CBCBXZCFWNODDR-UHFFFAOYSA-N	75453	6-(4-acrylamidophenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 8	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75453	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75453&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			674827	252652661							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120473	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H24N6O3/c1-4-24(36)34-21-9-5-20(6-10-21)27-25(26(28(30)37)23-15-32-18(3)16-35(23)27)19-7-11-22(12-8-19)38-29-31-14-13-17(2)33-29/h4-16H,1H2,2-3H3,(H2,30,37)(H,34,36)	CBCBXZCFWNODDR-UHFFFAOYSA-N	75453	6-(4-acrylamidophenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 8	Fibroblast growth factor receptor 4	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75453	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6750&target=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75453&enzyme=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search			674827	252652661							1	MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT	6IUP,6IUO,6YI8,4TYJ,4TYI,4TYG,4TYE,5NWZ,5NUD,7VJL,8W5C,7YSW	Fibroblast growth factor receptor 4	FGFR4_HUMAN	P22455	G3JVM2 G3JVM5 G3JVM7 G3JVM9 O43785 Q14309 Q71TW8 Q8TDA0 Q96KE5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120474	Cc1cn2c(-c3ccc(NC(=O)/C=C/CN(C)C)cc3)c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c2cn1	InChI=1S/C33H32N6O3/c1-21-7-5-9-29(36-21)42-26-16-12-23(13-17-26)30-31(33(34)41)27-19-35-22(2)20-39(27)32(30)24-10-14-25(15-11-24)37-28(40)8-6-18-38(3)4/h5-17,19-20H,18H2,1-4H3,(H2,34,41)(H,37,40)	YOPVLULZFZITKG-UHFFFAOYSA-N	75454	(E)-6-(4-(4-(dimethylamino)but-2-enamido)phenyl)-3-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 9	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75454	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75454&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2976279	252652662							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120475	Cc1cn2c(-c3ccc(NC(=O)/C=C/CN(C)C)cc3)c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c2cn1	InChI=1S/C33H32N6O3/c1-21-7-5-9-29(36-21)42-26-16-12-23(13-17-26)30-31(33(34)41)27-19-35-22(2)20-39(27)32(30)24-10-14-25(15-11-24)37-28(40)8-6-18-38(3)4/h5-17,19-20H,18H2,1-4H3,(H2,34,41)(H,37,40)	YOPVLULZFZITKG-UHFFFAOYSA-N	75454	(E)-6-(4-(4-(dimethylamino)but-2-enamido)phenyl)-3-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 9	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75454	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75454&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2976279	252652662							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120476	Cc1cn2c(-c3ccc(NC(=O)/C=C/CN(C)C)cc3)c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c2cn1	InChI=1S/C33H32N6O3/c1-21-7-5-9-29(36-21)42-26-16-12-23(13-17-26)30-31(33(34)41)27-19-35-22(2)20-39(27)32(30)24-10-14-25(15-11-24)37-28(40)8-6-18-38(3)4/h5-17,19-20H,18H2,1-4H3,(H2,34,41)(H,37,40)	YOPVLULZFZITKG-UHFFFAOYSA-N	75454	(E)-6-(4-(4-(dimethylamino)but-2-enamido)phenyl)-3-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 9	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75454	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75454&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2976279	252652662							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120477	Cc1cn2c(-c3ccc(NC(=O)/C=C/CN(C)C)nc3)c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c2cn1	InChI=1S/C32H31N7O3/c1-20-7-5-9-28(36-20)42-24-13-10-22(11-14-24)29-30(32(33)41)25-18-34-21(2)19-39(25)31(29)23-12-15-26(35-17-23)37-27(40)8-6-16-38(3)4/h5-15,17-19H,16H2,1-4H3,(H2,33,41)(H,35,37,40)	DBSOJSYLXKYVKD-UHFFFAOYSA-N	75455	(E)-6-(6-(4-(dimethylamino)but-2-enamido)pyridin-3-yl)-3-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 10	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75455	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75455&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1291333	252652663							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120478	Cc1cn2c(-c3ccc(NC(=O)/C=C/CN(C)C)nc3)c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c2cn1	InChI=1S/C32H31N7O3/c1-20-7-5-9-28(36-20)42-24-13-10-22(11-14-24)29-30(32(33)41)25-18-34-21(2)19-39(25)31(29)23-12-15-26(35-17-23)37-27(40)8-6-16-38(3)4/h5-15,17-19H,16H2,1-4H3,(H2,33,41)(H,35,37,40)	DBSOJSYLXKYVKD-UHFFFAOYSA-N	75455	(E)-6-(6-(4-(dimethylamino)but-2-enamido)pyridin-3-yl)-3-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 10	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75455	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75455&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1291333	252652663							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120479	Cc1cn2c(-c3ccc(NC(=O)/C=C/CN(C)C)nc3)c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c2cn1	InChI=1S/C32H31N7O3/c1-20-7-5-9-28(36-20)42-24-13-10-22(11-14-24)29-30(32(33)41)25-18-34-21(2)19-39(25)31(29)23-12-15-26(35-17-23)37-27(40)8-6-16-38(3)4/h5-15,17-19H,16H2,1-4H3,(H2,33,41)(H,35,37,40)	DBSOJSYLXKYVKD-UHFFFAOYSA-N	75455	(E)-6-(6-(4-(dimethylamino)but-2-enamido)pyridin-3-yl)-3-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 10	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75455	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75455&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1291333	252652663							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120480	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(CO)cn23)cc1	InChI=1S/C30H25N5O4/c1-3-25(37)34-21-11-7-20(8-12-21)29-27(28(30(31)38)24-15-32-22(17-36)16-35(24)29)19-9-13-23(14-10-19)39-26-6-4-5-18(2)33-26/h3-16,36H,1,17H2,2H3,(H2,31,38)(H,34,37)	CIWNAPJSHWDFST-UHFFFAOYSA-N	75456	6-(4-acrylamidophenyl)-3-(hydroxymethyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 11	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75456	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75456&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			897065	252652664							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120481	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(CO)cn23)cc1	InChI=1S/C30H25N5O4/c1-3-25(37)34-21-11-7-20(8-12-21)29-27(28(30(31)38)24-15-32-22(17-36)16-35(24)29)19-9-13-23(14-10-19)39-26-6-4-5-18(2)33-26/h3-16,36H,1,17H2,2H3,(H2,31,38)(H,34,37)	CIWNAPJSHWDFST-UHFFFAOYSA-N	75456	6-(4-acrylamidophenyl)-3-(hydroxymethyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 11	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75456	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75456&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			897065	252652664							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120482	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(CO)cn23)cc1	InChI=1S/C30H25N5O4/c1-3-25(37)34-21-11-7-20(8-12-21)29-27(28(30(31)38)24-15-32-22(17-36)16-35(24)29)19-9-13-23(14-10-19)39-26-6-4-5-18(2)33-26/h3-16,36H,1,17H2,2H3,(H2,31,38)(H,34,37)	CIWNAPJSHWDFST-UHFFFAOYSA-N	75456	6-(4-acrylamidophenyl)-3-(hydroxymethyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 11	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75456	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75456&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			897065	252652664							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120483	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(CO)cn23)cc1	InChI=1S/C30H25N5O4/c1-3-25(37)34-21-11-7-20(8-12-21)29-27(28(30(31)38)24-15-32-22(17-36)16-35(24)29)19-9-13-23(14-10-19)39-26-6-4-5-18(2)33-26/h3-16,36H,1,17H2,2H3,(H2,31,38)(H,34,37)	CIWNAPJSHWDFST-UHFFFAOYSA-N	75456	6-(4-acrylamidophenyl)-3-(hydroxymethyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 11	Fibroblast growth factor receptor 4	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75456	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6750&target=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75456&enzyme=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search			897065	252652664							1	MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT	6IUP,6IUO,6YI8,4TYJ,4TYI,4TYG,4TYE,5NWZ,5NUD,7VJL,8W5C,7YSW	Fibroblast growth factor receptor 4	FGFR4_HUMAN	P22455	G3JVM2 G3JVM5 G3JVM7 G3JVM9 O43785 Q14309 Q71TW8 Q8TDA0 Q96KE5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120484	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3c(NC)nccn23)cc1	InChI=1S/C30H26N6O3/c1-4-23(37)35-21-12-8-20(9-13-21)27-25(26(29(31)38)28-30(32-3)33-16-17-36(27)28)19-10-14-22(15-11-19)39-24-7-5-6-18(2)34-24/h4-17H,1H2,2-3H3,(H2,31,38)(H,32,33)(H,35,37)	RVJNDIWPYMJYSZ-UHFFFAOYSA-N	75457	6-(4-acrylamidophenyl)-1-(methylamino)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 12	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75457	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75457&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			6324543	252652665							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120485	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3c(NC)nccn23)cc1	InChI=1S/C30H26N6O3/c1-4-23(37)35-21-12-8-20(9-13-21)27-25(26(29(31)38)28-30(32-3)33-16-17-36(27)28)19-10-14-22(15-11-19)39-24-7-5-6-18(2)34-24/h4-17H,1H2,2-3H3,(H2,31,38)(H,32,33)(H,35,37)	RVJNDIWPYMJYSZ-UHFFFAOYSA-N	75457	6-(4-acrylamidophenyl)-1-(methylamino)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 12	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75457	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75457&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			6324543	252652665							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120486	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3c(NC)nccn23)cc1	InChI=1S/C30H26N6O3/c1-4-23(37)35-21-12-8-20(9-13-21)27-25(26(29(31)38)28-30(32-3)33-16-17-36(27)28)19-10-14-22(15-11-19)39-24-7-5-6-18(2)34-24/h4-17H,1H2,2-3H3,(H2,31,38)(H,32,33)(H,35,37)	RVJNDIWPYMJYSZ-UHFFFAOYSA-N	75457	6-(4-acrylamidophenyl)-1-(methylamino)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 12	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75457	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75457&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			6324543	252652665							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120487	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3n2CCN(C)C3)cc1	InChI=1S/C30H29N5O3/c1-4-25(36)33-22-12-8-21(9-13-22)29-27(28(30(31)37)24-18-34(3)16-17-35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-19(2)32-26/h4-15H,1,16-18H2,2-3H3,(H2,31,37)(H,33,36)	PHHKNAOFZSKEPY-UHFFFAOYSA-N	75458	6-(4-acrylamidophenyl)-2-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 13	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75458	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75458&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			5307801	252652666							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120488	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3n2CCN(C)C3)cc1	InChI=1S/C30H29N5O3/c1-4-25(36)33-22-12-8-21(9-13-22)29-27(28(30(31)37)24-18-34(3)16-17-35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-19(2)32-26/h4-15H,1,16-18H2,2-3H3,(H2,31,37)(H,33,36)	PHHKNAOFZSKEPY-UHFFFAOYSA-N	75458	6-(4-acrylamidophenyl)-2-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 13	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75458	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75458&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			5307801	252652666							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120489	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3n2CCN(C)C3)cc1	InChI=1S/C30H29N5O3/c1-4-25(36)33-22-12-8-21(9-13-22)29-27(28(30(31)37)24-18-34(3)16-17-35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-19(2)32-26/h4-15H,1,16-18H2,2-3H3,(H2,31,37)(H,33,36)	PHHKNAOFZSKEPY-UHFFFAOYSA-N	75458	6-(4-acrylamidophenyl)-2-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 13	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75458	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75458&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			5307801	252652666							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120490	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3n2CCN(C)C3)cc1	InChI=1S/C30H29N5O3/c1-4-25(36)33-22-12-8-21(9-13-22)29-27(28(30(31)37)24-18-34(3)16-17-35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-19(2)32-26/h4-15H,1,16-18H2,2-3H3,(H2,31,37)(H,33,36)	PHHKNAOFZSKEPY-UHFFFAOYSA-N	75458	6-(4-acrylamidophenyl)-2-methyl-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 13	Fibroblast growth factor receptor 4	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75458	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6750&target=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75458&enzyme=Fibroblast+growth+factor+receptor+4&column=ki&startPg=0&Increment=50&submit=Search			5307801	252652666							1	MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT	6IUP,6IUO,6YI8,4TYJ,4TYI,4TYG,4TYE,5NWZ,5NUD,7VJL,8W5C,7YSW	Fibroblast growth factor receptor 4	FGFR4_HUMAN	P22455	G3JVM2 G3JVM5 G3JVM7 G3JVM9 O43785 Q14309 Q71TW8 Q8TDA0 Q96KE5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120491	C=CC(=O)N1CCc2cc(-c3c(-c4ccc(Oc5cccc(C)n5)cc4)c(C(N)=O)c4cnccn34)ccc21	InChI=1S/C31H25N5O3/c1-3-27(37)35-15-13-21-17-22(9-12-24(21)35)30-28(29(31(32)38)25-18-33-14-16-36(25)30)20-7-10-23(11-8-20)39-26-6-4-5-19(2)34-26/h3-12,14,16-18H,1,13,15H2,2H3,(H2,32,38)	JUUFRMBRGIDHTK-UHFFFAOYSA-N	75459	6-(1-acryloylindolin-5-yl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 14	Fibroblast growth factor receptor 1	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75459	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75459&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			4606605	252652667							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120492	C=CC(=O)N1CCc2cc(-c3c(-c4ccc(Oc5cccc(C)n5)cc4)c(C(N)=O)c4cnccn34)ccc21	InChI=1S/C31H25N5O3/c1-3-27(37)35-15-13-21-17-22(9-12-24(21)35)30-28(29(31(32)38)25-18-33-14-16-36(25)30)20-7-10-23(11-8-20)39-26-6-4-5-19(2)34-26/h3-12,14,16-18H,1,13,15H2,2H3,(H2,32,38)	JUUFRMBRGIDHTK-UHFFFAOYSA-N	75459	6-(1-acryloylindolin-5-yl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 14	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75459	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75459&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			4606605	252652667							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120493	C=CC(=O)N1CCc2cc(-c3c(-c4ccc(Oc5cccc(C)n5)cc4)c(C(N)=O)c4cnccn34)ccc21	InChI=1S/C31H25N5O3/c1-3-27(37)35-15-13-21-17-22(9-12-24(21)35)30-28(29(31(32)38)25-18-33-14-16-36(25)30)20-7-10-23(11-8-20)39-26-6-4-5-19(2)34-26/h3-12,14,16-18H,1,13,15H2,2H3,(H2,32,38)	JUUFRMBRGIDHTK-UHFFFAOYSA-N	75459	6-(1-acryloylindolin-5-yl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 14	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75459	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75459&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			4606605	252652667							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120494	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3ccncn23)cc1	InChI=1S/C29H23N5O3/c1-3-24(35)33-21-11-7-20(8-12-21)28-26(27(29(30)36)23-15-16-31-17-34(23)28)19-9-13-22(14-10-19)37-25-6-4-5-18(2)32-25/h3-17H,1H2,2H3,(H2,30,36)(H,33,35)	IFQLLCCIZULODT-UHFFFAOYSA-N	75460	7-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 15	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75460	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75460&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			5044706	252652668							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120495	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3ccncn23)cc1	InChI=1S/C29H23N5O3/c1-3-24(35)33-21-11-7-20(8-12-21)28-26(27(29(30)36)23-15-16-31-17-34(23)28)19-9-13-22(14-10-19)37-25-6-4-5-18(2)32-25/h3-17H,1H2,2H3,(H2,30,36)(H,33,35)	IFQLLCCIZULODT-UHFFFAOYSA-N	75460	7-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 15	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75460	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75460&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			5044706	252652668							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120496	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3ccncn23)cc1	InChI=1S/C29H23N5O3/c1-3-24(35)33-21-11-7-20(8-12-21)28-26(27(29(30)36)23-15-16-31-17-34(23)28)19-9-13-22(14-10-19)37-25-6-4-5-18(2)32-25/h3-17H,1H2,2H3,(H2,30,36)(H,33,35)	IFQLLCCIZULODT-UHFFFAOYSA-N	75460	7-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 15	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75460	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75460&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			5044706	252652668							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120497	C=CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)CCC4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C29H26FN5O3/c1-2-23(36)34-21-10-8-19(9-11-21)26-24(25(27(31)37)22-16-32-14-15-35(22)26)18-4-6-20(7-5-18)28(38)33-17-29(30)12-3-13-29/h2,4-11,14-16H,1,3,12-13,17H2,(H2,31,37)(H,33,38)(H,34,36)	ZWAOMFXIDYGJLN-UHFFFAOYSA-N	75461	6-(4-acrylamidophenyl)-7-(4-(((1-fluorocyclobutyl)methyl)carbamoyl)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 16	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75461	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75461&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			756817	252652669							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120498	C=CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)CCC4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C29H26FN5O3/c1-2-23(36)34-21-10-8-19(9-11-21)26-24(25(27(31)37)22-16-32-14-15-35(22)26)18-4-6-20(7-5-18)28(38)33-17-29(30)12-3-13-29/h2,4-11,14-16H,1,3,12-13,17H2,(H2,31,37)(H,33,38)(H,34,36)	ZWAOMFXIDYGJLN-UHFFFAOYSA-N	75461	6-(4-acrylamidophenyl)-7-(4-(((1-fluorocyclobutyl)methyl)carbamoyl)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 16	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75461	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75461&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			756817	252652669							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120499	C=CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)CCC4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C29H26FN5O3/c1-2-23(36)34-21-10-8-19(9-11-21)26-24(25(27(31)37)22-16-32-14-15-35(22)26)18-4-6-20(7-5-18)28(38)33-17-29(30)12-3-13-29/h2,4-11,14-16H,1,3,12-13,17H2,(H2,31,37)(H,33,38)(H,34,36)	ZWAOMFXIDYGJLN-UHFFFAOYSA-N	75461	6-(4-acrylamidophenyl)-7-(4-(((1-fluorocyclobutyl)methyl)carbamoyl)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 16	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75461	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75461&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			756817	252652669							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120500	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(OC)cn23)cc1	InChI=1S/C30H25N5O4/c1-4-24(36)34-21-12-8-20(9-13-21)29-27(28(30(31)37)23-16-32-26(38-3)17-35(23)29)19-10-14-22(15-11-19)39-25-7-5-6-18(2)33-25/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	PLIKPAIJZQBWPW-UHFFFAOYSA-N	75462	6-(4-acrylamidophenyl)-3-methoxy-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 17	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75462	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75462&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			920218	252652670							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120501	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(OC)cn23)cc1	InChI=1S/C30H25N5O4/c1-4-24(36)34-21-12-8-20(9-13-21)29-27(28(30(31)37)23-16-32-26(38-3)17-35(23)29)19-10-14-22(15-11-19)39-25-7-5-6-18(2)33-25/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	PLIKPAIJZQBWPW-UHFFFAOYSA-N	75462	6-(4-acrylamidophenyl)-3-methoxy-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 17	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75462	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75462&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			920218	252652670							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120502	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(OC)cn23)cc1	InChI=1S/C30H25N5O4/c1-4-24(36)34-21-12-8-20(9-13-21)29-27(28(30(31)37)23-16-32-26(38-3)17-35(23)29)19-10-14-22(15-11-19)39-25-7-5-6-18(2)33-25/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	PLIKPAIJZQBWPW-UHFFFAOYSA-N	75462	6-(4-acrylamidophenyl)-3-methoxy-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 17	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75462	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75462&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			920218	252652670							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120503	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(S(=O)(=O)NC)cn23)cc1	InChI=1S/C30H26N6O5S/c1-4-24(37)35-21-12-8-20(9-13-21)29-27(19-10-14-22(15-11-19)41-25-7-5-6-18(2)34-25)28(30(31)38)23-16-33-26(17-36(23)29)42(39,40)32-3/h4-17,32H,1H2,2-3H3,(H2,31,38)(H,35,37)	CMIBZOXCYTZHBZ-UHFFFAOYSA-N	75464	6-(4-acrylamidophenyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)-3-(N-methylsulfamoyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 18	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75464	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75464&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			765586	252652672							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120504	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(S(=O)(=O)NC)cn23)cc1	InChI=1S/C30H26N6O5S/c1-4-24(37)35-21-12-8-20(9-13-21)29-27(19-10-14-22(15-11-19)41-25-7-5-6-18(2)34-25)28(30(31)38)23-16-33-26(17-36(23)29)42(39,40)32-3/h4-17,32H,1H2,2-3H3,(H2,31,38)(H,35,37)	CMIBZOXCYTZHBZ-UHFFFAOYSA-N	75464	6-(4-acrylamidophenyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)-3-(N-methylsulfamoyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 18	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75464	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75464&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			765586	252652672							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120505	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(S(=O)(=O)NC)cn23)cc1	InChI=1S/C30H26N6O5S/c1-4-24(37)35-21-12-8-20(9-13-21)29-27(19-10-14-22(15-11-19)41-25-7-5-6-18(2)34-25)28(30(31)38)23-16-33-26(17-36(23)29)42(39,40)32-3/h4-17,32H,1H2,2-3H3,(H2,31,38)(H,35,37)	CMIBZOXCYTZHBZ-UHFFFAOYSA-N	75464	6-(4-acrylamidophenyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)-3-(N-methylsulfamoyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 18	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75464	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75464&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			765586	252652672							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120506	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nc(C)cs4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C27H21N5O3S/c1-3-22(33)31-19-8-4-18(5-9-19)25-23(24(26(28)34)21-14-29-12-13-32(21)25)17-6-10-20(11-7-17)35-27-30-16(2)15-36-27/h3-15H,1H2,2H3,(H2,28,34)(H,31,33)	QTUJVWWCKRMOCD-UHFFFAOYSA-N	75465	Intermediate 19.1::6-(4-acrylamidophenyl)-7-(4-((4-methylthiazol-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 19	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75465	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75465&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			9547814	252652673							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120507	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nc(C)cs4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C27H21N5O3S/c1-3-22(33)31-19-8-4-18(5-9-19)25-23(24(26(28)34)21-14-29-12-13-32(21)25)17-6-10-20(11-7-17)35-27-30-16(2)15-36-27/h3-15H,1H2,2H3,(H2,28,34)(H,31,33)	QTUJVWWCKRMOCD-UHFFFAOYSA-N	75465	Intermediate 19.1::6-(4-acrylamidophenyl)-7-(4-((4-methylthiazol-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 19	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75465	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75465&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			9547814	252652673							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120508	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nc(C)cs4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C27H21N5O3S/c1-3-22(33)31-19-8-4-18(5-9-19)25-23(24(26(28)34)21-14-29-12-13-32(21)25)17-6-10-20(11-7-17)35-27-30-16(2)15-36-27/h3-15H,1H2,2H3,(H2,28,34)(H,31,33)	QTUJVWWCKRMOCD-UHFFFAOYSA-N	75465	Intermediate 19.1::6-(4-acrylamidophenyl)-7-(4-((4-methylthiazol-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 19	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75465	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75465&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			9547814	252652673							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120509	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cccnn23)cc1	InChI=1S/C29H23N5O3/c1-3-24(35)33-21-13-9-20(10-14-21)28-26(27(29(30)36)23-7-5-17-31-34(23)28)19-11-15-22(16-12-19)37-25-8-4-6-18(2)32-25/h3-17H,1H2,2H3,(H2,30,36)(H,33,35)	ROZATSASMRSBOR-UHFFFAOYSA-N	75466	7-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 20	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75466	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75466&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			4219136	252652674							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120510	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cccnn23)cc1	InChI=1S/C29H23N5O3/c1-3-24(35)33-21-13-9-20(10-14-21)28-26(27(29(30)36)23-7-5-17-31-34(23)28)19-11-15-22(16-12-19)37-25-8-4-6-18(2)32-25/h3-17H,1H2,2H3,(H2,30,36)(H,33,35)	ROZATSASMRSBOR-UHFFFAOYSA-N	75466	7-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 20	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75466	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75466&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			4219136	252652674							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120511	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cccnn23)cc1	InChI=1S/C29H23N5O3/c1-3-24(35)33-21-13-9-20(10-14-21)28-26(27(29(30)36)23-7-5-17-31-34(23)28)19-11-15-22(16-12-19)37-25-8-4-6-18(2)32-25/h3-17H,1H2,2H3,(H2,30,36)(H,33,35)	ROZATSASMRSBOR-UHFFFAOYSA-N	75466	7-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 20	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75466	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75466&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			4219136	252652674							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120512	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C4CN(C)C4)cn23)cc1	InChI=1S/C33H30N6O3/c1-4-28(40)37-24-12-8-22(9-13-24)32-30(21-10-14-25(15-11-21)42-29-7-5-6-20(2)36-29)31(33(34)41)27-16-35-26(19-39(27)32)23-17-38(3)18-23/h4-16,19,23H,1,17-18H2,2-3H3,(H2,34,41)(H,37,40)	YQBZRFOHNMPDDO-UHFFFAOYSA-N	75467	6-(4-acrylamidophenyl)-3-(1-methylazetidin-3-yl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 21	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75467	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75467&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1477797	252652675							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120513	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C4CN(C)C4)cn23)cc1	InChI=1S/C33H30N6O3/c1-4-28(40)37-24-12-8-22(9-13-24)32-30(21-10-14-25(15-11-21)42-29-7-5-6-20(2)36-29)31(33(34)41)27-16-35-26(19-39(27)32)23-17-38(3)18-23/h4-16,19,23H,1,17-18H2,2-3H3,(H2,34,41)(H,37,40)	YQBZRFOHNMPDDO-UHFFFAOYSA-N	75467	6-(4-acrylamidophenyl)-3-(1-methylazetidin-3-yl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 21	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75467	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75467&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1477797	252652675							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120514	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C4CN(C)C4)cn23)cc1	InChI=1S/C33H30N6O3/c1-4-28(40)37-24-12-8-22(9-13-24)32-30(21-10-14-25(15-11-21)42-29-7-5-6-20(2)36-29)31(33(34)41)27-16-35-26(19-39(27)32)23-17-38(3)18-23/h4-16,19,23H,1,17-18H2,2-3H3,(H2,34,41)(H,37,40)	YQBZRFOHNMPDDO-UHFFFAOYSA-N	75467	6-(4-acrylamidophenyl)-3-(1-methylazetidin-3-yl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 21	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75467	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75467&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1477797	252652675							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120515	C=CC(=O)Nc1ccc(-c2c(-c3ccc(OC)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C24H20N4O3/c1-3-20(29)27-17-8-4-16(5-9-17)23-21(15-6-10-18(31-2)11-7-15)22(24(25)30)19-14-26-12-13-28(19)23/h3-14H,1H2,2H3,(H2,25,30)(H,27,29)	KDIOUIVNKFHVHC-UHFFFAOYSA-N	75468	6-(4-acrylamidophenyl)-7-(4-methoxyphenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 22	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75468	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75468&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			670792	252652676							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120516	C=CC(=O)Nc1ccc(-c2c(-c3ccc(OC)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C24H20N4O3/c1-3-20(29)27-17-8-4-16(5-9-17)23-21(15-6-10-18(31-2)11-7-15)22(24(25)30)19-14-26-12-13-28(19)23/h3-14H,1H2,2H3,(H2,25,30)(H,27,29)	KDIOUIVNKFHVHC-UHFFFAOYSA-N	75468	6-(4-acrylamidophenyl)-7-(4-methoxyphenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 22	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75468	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75468&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			670792	252652676							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120517	C=CC(=O)Nc1ccc(-c2c(-c3ccc(OC)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C24H20N4O3/c1-3-20(29)27-17-8-4-16(5-9-17)23-21(15-6-10-18(31-2)11-7-15)22(24(25)30)19-14-26-12-13-28(19)23/h3-14H,1H2,2H3,(H2,25,30)(H,27,29)	KDIOUIVNKFHVHC-UHFFFAOYSA-N	75468	6-(4-acrylamidophenyl)-7-(4-methoxyphenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 22	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75468	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75468&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			670792	252652676							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120518	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3sccn23)cc1	InChI=1S/C28H22N4O3S/c1-3-22(33)31-20-11-7-19(8-12-20)26-24(25(27(29)34)28-32(26)15-16-36-28)18-9-13-21(14-10-18)35-23-6-4-5-17(2)30-23/h3-16H,1H2,2H3,(H2,29,34)(H,31,33)	DYPZPFBMWLIPLU-UHFFFAOYSA-N	75469	5-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[2,1-b]thiazole-7-carboxamide::US20250382297, Example 23	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75469	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75469&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			749682	252652677							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120519	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3sccn23)cc1	InChI=1S/C28H22N4O3S/c1-3-22(33)31-20-11-7-19(8-12-20)26-24(25(27(29)34)28-32(26)15-16-36-28)18-9-13-21(14-10-18)35-23-6-4-5-17(2)30-23/h3-16H,1H2,2H3,(H2,29,34)(H,31,33)	DYPZPFBMWLIPLU-UHFFFAOYSA-N	75469	5-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[2,1-b]thiazole-7-carboxamide::US20250382297, Example 23	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75469	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75469&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			749682	252652677							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120520	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3sccn23)cc1	InChI=1S/C28H22N4O3S/c1-3-22(33)31-20-11-7-19(8-12-20)26-24(25(27(29)34)28-32(26)15-16-36-28)18-9-13-21(14-10-18)35-23-6-4-5-17(2)30-23/h3-16H,1H2,2H3,(H2,29,34)(H,31,33)	DYPZPFBMWLIPLU-UHFFFAOYSA-N	75469	5-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[2,1-b]thiazole-7-carboxamide::US20250382297, Example 23	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75469	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75469&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			749682	252652677							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120521	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C#N)c3sccn23)cc1	InChI=1S/C28H20N4O2S/c1-3-24(33)31-21-11-7-20(8-12-21)27-26(23(17-29)28-32(27)15-16-35-28)19-9-13-22(14-10-19)34-25-6-4-5-18(2)30-25/h3-16H,1H2,2H3,(H,31,33)	ZPSIIXDQLIITOC-UHFFFAOYSA-N	75470	N-(4-(7-cyano-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[2,1-b]thiazol-5-yl)phenyl) acrylamide::N-(4-(7-cyano-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[2,1-b]thiazol-5-yl)phenyl)acrylamide::US20250382297, Example 24	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75470	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75470&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			880469	252652678							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120522	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C#N)c3sccn23)cc1	InChI=1S/C28H20N4O2S/c1-3-24(33)31-21-11-7-20(8-12-21)27-26(23(17-29)28-32(27)15-16-35-28)19-9-13-22(14-10-19)34-25-6-4-5-18(2)30-25/h3-16H,1H2,2H3,(H,31,33)	ZPSIIXDQLIITOC-UHFFFAOYSA-N	75470	N-(4-(7-cyano-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[2,1-b]thiazol-5-yl)phenyl) acrylamide::N-(4-(7-cyano-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[2,1-b]thiazol-5-yl)phenyl)acrylamide::US20250382297, Example 24	Fibroblast growth factor receptor 2	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75470	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75470&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			880469	252652678							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120523	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C#N)c3sccn23)cc1	InChI=1S/C28H20N4O2S/c1-3-24(33)31-21-11-7-20(8-12-21)27-26(23(17-29)28-32(27)15-16-35-28)19-9-13-22(14-10-19)34-25-6-4-5-18(2)30-25/h3-16H,1H2,2H3,(H,31,33)	ZPSIIXDQLIITOC-UHFFFAOYSA-N	75470	N-(4-(7-cyano-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[2,1-b]thiazol-5-yl)phenyl) acrylamide::N-(4-(7-cyano-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[2,1-b]thiazol-5-yl)phenyl)acrylamide::US20250382297, Example 24	Fibroblast growth factor receptor 3	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75470	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75470&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			880469	252652678							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120524	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)c(OC)c3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C30H25N5O4/c1-4-25(36)34-21-11-8-19(9-12-21)29-27(28(30(31)37)22-17-32-14-15-35(22)29)20-10-13-23(24(16-20)38-3)39-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	ZJCXFLLJJQWOBW-UHFFFAOYSA-N	75471	6-(4-acrylamidophenyl)-7-(3-methoxy-4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 25	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75471	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75471&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			6401684	252652679							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120525	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)c(OC)c3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C30H25N5O4/c1-4-25(36)34-21-11-8-19(9-12-21)29-27(28(30(31)37)22-17-32-14-15-35(22)29)20-10-13-23(24(16-20)38-3)39-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	ZJCXFLLJJQWOBW-UHFFFAOYSA-N	75471	6-(4-acrylamidophenyl)-7-(3-methoxy-4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 25	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75471	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75471&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			6401684	252652679							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120526	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)c(OC)c3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C30H25N5O4/c1-4-25(36)34-21-11-8-19(9-12-21)29-27(28(30(31)37)22-17-32-14-15-35(22)29)20-10-13-23(24(16-20)38-3)39-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	ZJCXFLLJJQWOBW-UHFFFAOYSA-N	75471	6-(4-acrylamidophenyl)-7-(3-methoxy-4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 25	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75471	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75471&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			6401684	252652679							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120527	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4ccccn4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H21N5O3/c1-2-23(34)32-20-10-6-19(7-11-20)27-25(26(28(29)35)22-17-30-15-16-33(22)27)18-8-12-21(13-9-18)36-24-5-3-4-14-31-24/h2-17H,1H2,(H2,29,35)(H,32,34)	YFWZCORSYXWLDM-UHFFFAOYSA-N	75472	6-(4-acrylamidophenyl)-7-(4-(pyridin-2-yloxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 26	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75472	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75472&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2063537	252652680							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120528	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4ccccn4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H21N5O3/c1-2-23(34)32-20-10-6-19(7-11-20)27-25(26(28(29)35)22-17-30-15-16-33(22)27)18-8-12-21(13-9-18)36-24-5-3-4-14-31-24/h2-17H,1H2,(H2,29,35)(H,32,34)	YFWZCORSYXWLDM-UHFFFAOYSA-N	75472	6-(4-acrylamidophenyl)-7-(4-(pyridin-2-yloxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 26	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75472	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75472&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2063537	252652680							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120529	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4ccccn4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H21N5O3/c1-2-23(34)32-20-10-6-19(7-11-20)27-25(26(28(29)35)22-17-30-15-16-33(22)27)18-8-12-21(13-9-18)36-24-5-3-4-14-31-24/h2-17H,1H2,(H2,29,35)(H,32,34)	YFWZCORSYXWLDM-UHFFFAOYSA-N	75472	6-(4-acrylamidophenyl)-7-(4-(pyridin-2-yloxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 26	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75472	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75472&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2063537	252652680							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120530	C=CC(=O)Nc1ccc(-c2c(-c3ccc(S(=O)(=O)C4CC4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C26H22N4O4S/c1-2-22(31)29-18-7-3-17(4-8-18)25-23(24(26(27)32)21-15-28-13-14-30(21)25)16-5-9-19(10-6-16)35(33,34)20-11-12-20/h2-10,13-15,20H,1,11-12H2,(H2,27,32)(H,29,31)	WUHFODHSRSPZAK-UHFFFAOYSA-N	75473	6-(4-acrylamidophenyl)-7-(4-(cyclopropylsulfonyl)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 27	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75473	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75473&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2337793	252652681							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120531	C=CC(=O)Nc1ccc(-c2c(-c3ccc(S(=O)(=O)C4CC4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C26H22N4O4S/c1-2-22(31)29-18-7-3-17(4-8-18)25-23(24(26(27)32)21-15-28-13-14-30(21)25)16-5-9-19(10-6-16)35(33,34)20-11-12-20/h2-10,13-15,20H,1,11-12H2,(H2,27,32)(H,29,31)	WUHFODHSRSPZAK-UHFFFAOYSA-N	75473	6-(4-acrylamidophenyl)-7-(4-(cyclopropylsulfonyl)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 27	Fibroblast growth factor receptor 2	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75473	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75473&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2337793	252652681							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120532	C=CC(=O)Nc1ccc(-c2c(-c3ccc(S(=O)(=O)C4CC4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C26H22N4O4S/c1-2-22(31)29-18-7-3-17(4-8-18)25-23(24(26(27)32)21-15-28-13-14-30(21)25)16-5-9-19(10-6-16)35(33,34)20-11-12-20/h2-10,13-15,20H,1,11-12H2,(H2,27,32)(H,29,31)	WUHFODHSRSPZAK-UHFFFAOYSA-N	75473	6-(4-acrylamidophenyl)-7-(4-(cyclopropylsulfonyl)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 27	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75473	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75473&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2337793	252652681							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120533	C=CC(=O)Nc1ccc(-c2c(-c3ccc(OC4CCCC4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H26N4O3/c1-2-24(33)31-20-11-7-19(8-12-20)27-25(26(28(29)34)23-17-30-15-16-32(23)27)18-9-13-22(14-10-18)35-21-5-3-4-6-21/h2,7-17,21H,1,3-6H2,(H2,29,34)(H,31,33)	SFXISAYQIZPKEI-UHFFFAOYSA-N	75474	6-(4-acrylamidophenyl)-7-(4-(cyclopentyloxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 28	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75474	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75474&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			6508152	252652682							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120534	C=CC(=O)Nc1ccc(-c2c(-c3ccc(OC4CCCC4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H26N4O3/c1-2-24(33)31-20-11-7-19(8-12-20)27-25(26(28(29)34)23-17-30-15-16-32(23)27)18-9-13-22(14-10-18)35-21-5-3-4-6-21/h2,7-17,21H,1,3-6H2,(H2,29,34)(H,31,33)	SFXISAYQIZPKEI-UHFFFAOYSA-N	75474	6-(4-acrylamidophenyl)-7-(4-(cyclopentyloxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 28	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75474	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75474&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			6508152	252652682							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120535	C=CC(=O)Nc1ccc(-c2c(-c3ccc(OC4CCCC4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H26N4O3/c1-2-24(33)31-20-11-7-19(8-12-20)27-25(26(28(29)34)23-17-30-15-16-32(23)27)18-9-13-22(14-10-18)35-21-5-3-4-6-21/h2,7-17,21H,1,3-6H2,(H2,29,34)(H,31,33)	SFXISAYQIZPKEI-UHFFFAOYSA-N	75474	6-(4-acrylamidophenyl)-7-(4-(cyclopentyloxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 28	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75474	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75474&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			6508152	252652682							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120536	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(CN(C)C)cn23)cc1	InChI=1S/C32H30N6O3/c1-5-27(39)36-23-13-9-22(10-14-23)31-29(21-11-15-25(16-12-21)41-28-8-6-7-20(2)35-28)30(32(33)40)26-17-34-24(18-37(3)4)19-38(26)31/h5-17,19H,1,18H2,2-4H3,(H2,33,40)(H,36,39)	LIMABKKUCCMSFV-UHFFFAOYSA-N	75475	6-(4-acrylamidophenyl)-3-((dimethylamino)methyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 29	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75475	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75475&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			4197825	252652683							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120537	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(CN(C)C)cn23)cc1	InChI=1S/C32H30N6O3/c1-5-27(39)36-23-13-9-22(10-14-23)31-29(21-11-15-25(16-12-21)41-28-8-6-7-20(2)35-28)30(32(33)40)26-17-34-24(18-37(3)4)19-38(26)31/h5-17,19H,1,18H2,2-4H3,(H2,33,40)(H,36,39)	LIMABKKUCCMSFV-UHFFFAOYSA-N	75475	6-(4-acrylamidophenyl)-3-((dimethylamino)methyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 29	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75475	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75475&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			4197825	252652683							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120538	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(CN(C)C)cn23)cc1	InChI=1S/C32H30N6O3/c1-5-27(39)36-23-13-9-22(10-14-23)31-29(21-11-15-25(16-12-21)41-28-8-6-7-20(2)35-28)30(32(33)40)26-17-34-24(18-37(3)4)19-38(26)31/h5-17,19H,1,18H2,2-4H3,(H2,33,40)(H,36,39)	LIMABKKUCCMSFV-UHFFFAOYSA-N	75475	6-(4-acrylamidophenyl)-3-((dimethylamino)methyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 29	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75475	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75475&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			4197825	252652683							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120539	C=CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)N4CC5(CCC5)C4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C30H27N5O3/c1-2-24(36)33-22-10-8-20(9-11-22)27-25(26(28(31)37)23-16-32-14-15-35(23)27)19-4-6-21(7-5-19)29(38)34-17-30(18-34)12-3-13-30/h2,4-11,14-16H,1,3,12-13,17-18H2,(H2,31,37)(H,33,36)	VZWXOOIZMWYVNF-UHFFFAOYSA-N	75476	7-(4-(2-azaspiro[3.3]heptane-2-carbonyl)phenyl)-6-(4-acrylamidophenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 30	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75476	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75476&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1487824	252652684							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120540	C=CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)N4CC5(CCC5)C4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C30H27N5O3/c1-2-24(36)33-22-10-8-20(9-11-22)27-25(26(28(31)37)23-16-32-14-15-35(23)27)19-4-6-21(7-5-19)29(38)34-17-30(18-34)12-3-13-30/h2,4-11,14-16H,1,3,12-13,17-18H2,(H2,31,37)(H,33,36)	VZWXOOIZMWYVNF-UHFFFAOYSA-N	75476	7-(4-(2-azaspiro[3.3]heptane-2-carbonyl)phenyl)-6-(4-acrylamidophenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 30	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75476	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75476&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1487824	252652684							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120541	C=CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)N4CC5(CCC5)C4)cc3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C30H27N5O3/c1-2-24(36)33-22-10-8-20(9-11-22)27-25(26(28(31)37)23-16-32-14-15-35(23)27)19-4-6-21(7-5-19)29(38)34-17-30(18-34)12-3-13-30/h2,4-11,14-16H,1,3,12-13,17-18H2,(H2,31,37)(H,33,36)	VZWXOOIZMWYVNF-UHFFFAOYSA-N	75476	7-(4-(2-azaspiro[3.3]heptane-2-carbonyl)phenyl)-6-(4-acrylamidophenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 30	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75476	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75476&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1487824	252652684							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120542	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)c(F)c3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C29H22FN5O3/c1-3-24(36)34-20-10-7-18(8-11-20)28-26(27(29(31)37)22-16-32-13-14-35(22)28)19-9-12-23(21(30)15-19)38-25-6-4-5-17(2)33-25/h3-16H,1H2,2H3,(H2,31,37)(H,34,36)	BVKWFCAHIZDXHV-UHFFFAOYSA-N	75477	6-(4-acrylamidophenyl)-7-(3-fluoro-4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 32	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75477	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75477&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			5756334	252652685							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120543	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)c(F)c3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C29H22FN5O3/c1-3-24(36)34-20-10-7-18(8-11-20)28-26(27(29(31)37)22-16-32-13-14-35(22)28)19-9-12-23(21(30)15-19)38-25-6-4-5-17(2)33-25/h3-16H,1H2,2H3,(H2,31,37)(H,34,36)	BVKWFCAHIZDXHV-UHFFFAOYSA-N	75477	6-(4-acrylamidophenyl)-7-(3-fluoro-4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 32	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75477	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75477&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			5756334	252652685							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120544	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)c(F)c3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C29H22FN5O3/c1-3-24(36)34-20-10-7-18(8-11-20)28-26(27(29(31)37)22-16-32-13-14-35(22)28)19-9-12-23(21(30)15-19)38-25-6-4-5-17(2)33-25/h3-16H,1H2,2H3,(H2,31,37)(H,34,36)	BVKWFCAHIZDXHV-UHFFFAOYSA-N	75477	6-(4-acrylamidophenyl)-7-(3-fluoro-4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 32	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75477	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75477&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			5756334	252652685							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120545	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H21FN6O3/c1-3-23(36)34-19-7-4-17(5-8-19)26-24(25(27(30)37)21-15-31-12-13-35(21)26)18-6-9-22(20(29)14-18)38-28-32-11-10-16(2)33-28/h3-15H,1H2,2H3,(H2,30,37)(H,34,36)	GCMYVTXWHLYTAS-UHFFFAOYSA-N	75478	6-(4-acrylamidophenyl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 33	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75478	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75478&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			9587156	252652686							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120546	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H21FN6O3/c1-3-23(36)34-19-7-4-17(5-8-19)26-24(25(27(30)37)21-15-31-12-13-35(21)26)18-6-9-22(20(29)14-18)38-28-32-11-10-16(2)33-28/h3-15H,1H2,2H3,(H2,30,37)(H,34,36)	GCMYVTXWHLYTAS-UHFFFAOYSA-N	75478	6-(4-acrylamidophenyl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 33	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75478	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75478&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			9587156	252652686							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120547	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C28H21FN6O3/c1-3-23(36)34-19-7-4-17(5-8-19)26-24(25(27(30)37)21-15-31-12-13-35(21)26)18-6-9-22(20(29)14-18)38-28-32-11-10-16(2)33-28/h3-15H,1H2,2H3,(H2,30,37)(H,34,36)	GCMYVTXWHLYTAS-UHFFFAOYSA-N	75478	6-(4-acrylamidophenyl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 33	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75478	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75478&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			9587156	252652686							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120548	C=C(C)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C29H23FN6O3/c1-16(2)28(38)35-20-7-4-18(5-8-20)26-24(25(27(31)37)22-15-32-12-13-36(22)26)19-6-9-23(21(30)14-19)39-29-33-11-10-17(3)34-29/h4-15H,1H2,2-3H3,(H2,31,37)(H,35,38)	PUYRUXHDUGPKJA-UHFFFAOYSA-N	75479	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(4-methacrylamidophenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 34	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75479	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75479&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1375607	252652687							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120549	C=C(C)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C29H23FN6O3/c1-16(2)28(38)35-20-7-4-18(5-8-20)26-24(25(27(31)37)22-15-32-12-13-36(22)26)19-6-9-23(21(30)14-19)39-29-33-11-10-17(3)34-29/h4-15H,1H2,2-3H3,(H2,31,37)(H,35,38)	PUYRUXHDUGPKJA-UHFFFAOYSA-N	75479	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(4-methacrylamidophenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 34	Fibroblast growth factor receptor 2	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75479	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75479&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1375607	252652687							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120550	C=C(C)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnccn23)cc1	InChI=1S/C29H23FN6O3/c1-16(2)28(38)35-20-7-4-18(5-8-20)26-24(25(27(31)37)22-15-32-12-13-36(22)26)19-6-9-23(21(30)14-19)39-29-33-11-10-17(3)34-29/h4-15H,1H2,2-3H3,(H2,31,37)(H,35,38)	PUYRUXHDUGPKJA-UHFFFAOYSA-N	75479	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(4-methacrylamidophenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 34	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75479	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75479&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1375607	252652687							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120551	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H23FN6O3/c1-4-24(37)35-20-8-5-18(6-9-20)27-25(26(28(31)38)22-14-33-17(3)15-36(22)27)19-7-10-23(21(30)13-19)39-29-32-12-11-16(2)34-29/h4-15H,1H2,2-3H3,(H2,31,38)(H,35,37)	QRFUZJXUXVBLFZ-UHFFFAOYSA-N	75480	6-(4-acrylamidophenyl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 35	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75480	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75480&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			5424934	252652688							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120552	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H23FN6O3/c1-4-24(37)35-20-8-5-18(6-9-20)27-25(26(28(31)38)22-14-33-17(3)15-36(22)27)19-7-10-23(21(30)13-19)39-29-32-12-11-16(2)34-29/h4-15H,1H2,2-3H3,(H2,31,38)(H,35,37)	QRFUZJXUXVBLFZ-UHFFFAOYSA-N	75480	6-(4-acrylamidophenyl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 35	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75480	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75480&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			5424934	252652688							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120553	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H23FN6O3/c1-4-24(37)35-20-8-5-18(6-9-20)27-25(26(28(31)38)22-14-33-17(3)15-36(22)27)19-7-10-23(21(30)13-19)39-29-32-12-11-16(2)34-29/h4-15H,1H2,2-3H3,(H2,31,38)(H,35,37)	QRFUZJXUXVBLFZ-UHFFFAOYSA-N	75480	6-(4-acrylamidophenyl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 35	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75480	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75480&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			5424934	252652688							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120554	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cn1	InChI=1S/C28H22FN7O3/c1-4-23(37)35-22-8-6-18(12-33-22)26-24(25(27(30)38)20-13-32-16(3)14-36(20)26)17-5-7-21(19(29)11-17)39-28-31-10-9-15(2)34-28/h4-14H,1H2,2-3H3,(H2,30,38)(H,33,35,37)	FHXHKJRUZFOERK-UHFFFAOYSA-N	75481	US20250382297, Example 36	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75481	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75481&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			91898138	252652689							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120555	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cn1	InChI=1S/C28H22FN7O3/c1-4-23(37)35-22-8-6-18(12-33-22)26-24(25(27(30)38)20-13-32-16(3)14-36(20)26)17-5-7-21(19(29)11-17)39-28-31-10-9-15(2)34-28/h4-14H,1H2,2-3H3,(H2,30,38)(H,33,35,37)	FHXHKJRUZFOERK-UHFFFAOYSA-N	75481	US20250382297, Example 36	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75481	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75481&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			91898138	252652689							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120556	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cn1	InChI=1S/C28H22FN7O3/c1-4-23(37)35-22-8-6-18(12-33-22)26-24(25(27(30)38)20-13-32-16(3)14-36(20)26)17-5-7-21(19(29)11-17)39-28-31-10-9-15(2)34-28/h4-14H,1H2,2-3H3,(H2,30,38)(H,33,35,37)	FHXHKJRUZFOERK-UHFFFAOYSA-N	75481	US20250382297, Example 36	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75481	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75481&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			91898138	252652689							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120557	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1C	InChI=1S/C30H25FN6O3/c1-5-25(38)36-22-8-6-20(12-16(22)2)28-26(27(29(32)39)23-14-34-18(4)15-37(23)28)19-7-9-24(21(31)13-19)40-30-33-11-10-17(3)35-30/h5-15H,1H2,2-4H3,(H2,32,39)(H,36,38)	VWUJWSYPBZOQTR-UHFFFAOYSA-N	75482	US20250382297, Example 37	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75482	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75482&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			91898139	252652690							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120558	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1C	InChI=1S/C30H25FN6O3/c1-5-25(38)36-22-8-6-20(12-16(22)2)28-26(27(29(32)39)23-14-34-18(4)15-37(23)28)19-7-9-24(21(31)13-19)40-30-33-11-10-17(3)35-30/h5-15H,1H2,2-4H3,(H2,32,39)(H,36,38)	VWUJWSYPBZOQTR-UHFFFAOYSA-N	75482	US20250382297, Example 37	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75482	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75482&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			91898139	252652690							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120559	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1C	InChI=1S/C30H25FN6O3/c1-5-25(38)36-22-8-6-20(12-16(22)2)28-26(27(29(32)39)23-14-34-18(4)15-37(23)28)19-7-9-24(21(31)13-19)40-30-33-11-10-17(3)35-30/h5-15H,1H2,2-4H3,(H2,32,39)(H,36,38)	VWUJWSYPBZOQTR-UHFFFAOYSA-N	75482	US20250382297, Example 37	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75482	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75482&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			91898139	252652690							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120560	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1OC	InChI=1S/C30H26N6O4/c1-5-25(37)35-22-11-8-20(14-24(22)39-4)28-26(27(29(31)38)23-15-33-18(3)16-36(23)28)19-6-9-21(10-7-19)40-30-32-13-12-17(2)34-30/h5-16H,1H2,2-4H3,(H2,31,38)(H,35,37)	CRXGWRVZPXHWQG-UHFFFAOYSA-N	75483	US20250382297, Example 38	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75483	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75483&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			91898140	252652691							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120561	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1OC	InChI=1S/C30H26N6O4/c1-5-25(37)35-22-11-8-20(14-24(22)39-4)28-26(27(29(31)38)23-15-33-18(3)16-36(23)28)19-6-9-21(10-7-19)40-30-32-13-12-17(2)34-30/h5-16H,1H2,2-4H3,(H2,31,38)(H,35,37)	CRXGWRVZPXHWQG-UHFFFAOYSA-N	75483	US20250382297, Example 38	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75483	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75483&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			91898140	252652691							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120562	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1OC	InChI=1S/C30H26N6O4/c1-5-25(37)35-22-11-8-20(14-24(22)39-4)28-26(27(29(31)38)23-15-33-18(3)16-36(23)28)19-6-9-21(10-7-19)40-30-32-13-12-17(2)34-30/h5-16H,1H2,2-4H3,(H2,31,38)(H,35,37)	CRXGWRVZPXHWQG-UHFFFAOYSA-N	75483	US20250382297, Example 38	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75483	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75483&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			91898140	252652691							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120563	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H23FN6O3/c1-16-12-13-32-29(34-16)39-22-10-6-19(7-11-22)24-25(27(31)37)23-14-33-17(2)15-36(23)26(24)20-4-8-21(9-5-20)35-28(38)18(3)30/h4-15H,3H2,1-2H3,(H2,31,37)(H,35,38)	QOTHEKIYUNNSPZ-UHFFFAOYSA-N	75484	US20250382297, Example 39	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75484	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75484&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			921858	252652692							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120564	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H23FN6O3/c1-16-12-13-32-29(34-16)39-22-10-6-19(7-11-22)24-25(27(31)37)23-14-33-17(2)15-36(23)26(24)20-4-8-21(9-5-20)35-28(38)18(3)30/h4-15H,3H2,1-2H3,(H2,31,37)(H,35,38)	QOTHEKIYUNNSPZ-UHFFFAOYSA-N	75484	US20250382297, Example 39	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75484	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75484&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			921858	252652692							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120565	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H23FN6O3/c1-16-12-13-32-29(34-16)39-22-10-6-19(7-11-22)24-25(27(31)37)23-14-33-17(2)15-36(23)26(24)20-4-8-21(9-5-20)35-28(38)18(3)30/h4-15H,3H2,1-2H3,(H2,31,37)(H,35,38)	QOTHEKIYUNNSPZ-UHFFFAOYSA-N	75484	US20250382297, Example 39	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75484	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75484&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			921858	252652692							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120566	C=C(F)C(=O)Nc1cccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)c1	InChI=1S/C29H23FN6O3/c1-16-11-12-32-29(34-16)39-22-9-7-19(8-10-22)24-25(27(31)37)23-14-33-17(2)15-36(23)26(24)20-5-4-6-21(13-20)35-28(38)18(3)30/h4-15H,3H2,1-2H3,(H2,31,37)(H,35,38)	RQZTWADNEZTPHJ-UHFFFAOYSA-N	75485	US20250382297, Example 40	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75485	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75485&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			948125	242053595							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120567	C=C(F)C(=O)Nc1cccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)c1	InChI=1S/C29H23FN6O3/c1-16-11-12-32-29(34-16)39-22-9-7-19(8-10-22)24-25(27(31)37)23-14-33-17(2)15-36(23)26(24)20-5-4-6-21(13-20)35-28(38)18(3)30/h4-15H,3H2,1-2H3,(H2,31,37)(H,35,38)	RQZTWADNEZTPHJ-UHFFFAOYSA-N	75485	US20250382297, Example 40	Fibroblast growth factor receptor 2	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75485	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75485&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			948125	242053595							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120568	C=C(F)C(=O)Nc1cccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)c1	InChI=1S/C29H23FN6O3/c1-16-11-12-32-29(34-16)39-22-9-7-19(8-10-22)24-25(27(31)37)23-14-33-17(2)15-36(23)26(24)20-5-4-6-21(13-20)35-28(38)18(3)30/h4-15H,3H2,1-2H3,(H2,31,37)(H,35,38)	RQZTWADNEZTPHJ-UHFFFAOYSA-N	75485	US20250382297, Example 40	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75485	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75485&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			948125	242053595							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120569	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-10-11-33-29(35-15)40-23-9-6-19(12-21(23)31)24-25(27(32)38)22-13-34-16(2)14-37(22)26(24)18-4-7-20(8-5-18)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	GWJVNXZJSVXKGL-UHFFFAOYSA-N	75486	US20250382297, Example 41	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75486	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75486&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			9635811	252652693							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120570	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-10-11-33-29(35-15)40-23-9-6-19(12-21(23)31)24-25(27(32)38)22-13-34-16(2)14-37(22)26(24)18-4-7-20(8-5-18)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	GWJVNXZJSVXKGL-UHFFFAOYSA-N	75486	US20250382297, Example 41	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75486	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75486&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			9635811	252652693							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120571	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-10-11-33-29(35-15)40-23-9-6-19(12-21(23)31)24-25(27(32)38)22-13-34-16(2)14-37(22)26(24)18-4-7-20(8-5-18)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	GWJVNXZJSVXKGL-UHFFFAOYSA-N	75486	US20250382297, Example 41	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75486	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75486&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			9635811	252652693							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120572	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)c(F)c1	InChI=1S/C29H22F2N6O3/c1-15-10-11-33-29(35-15)40-20-7-4-18(5-8-20)24-25(27(32)38)23-13-34-16(2)14-37(23)26(24)21-9-6-19(12-22(21)31)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	XIHWXLMTXSNNMJ-UHFFFAOYSA-N	75487	US20250382297, Example 42	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75487	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75487&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1422791	252652694							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120573	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)c(F)c1	InChI=1S/C29H22F2N6O3/c1-15-10-11-33-29(35-15)40-20-7-4-18(5-8-20)24-25(27(32)38)23-13-34-16(2)14-37(23)26(24)21-9-6-19(12-22(21)31)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	XIHWXLMTXSNNMJ-UHFFFAOYSA-N	75487	US20250382297, Example 42	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75487	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75487&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1422791	252652694							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120574	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)c(F)c1	InChI=1S/C29H22F2N6O3/c1-15-10-11-33-29(35-15)40-20-7-4-18(5-8-20)24-25(27(32)38)23-13-34-16(2)14-37(23)26(24)21-9-6-19(12-22(21)31)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	XIHWXLMTXSNNMJ-UHFFFAOYSA-N	75487	US20250382297, Example 42	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75487	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75487&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1422791	252652694							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120575	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)c(F)c1	InChI=1S/C29H21F3N6O3/c1-14-8-9-34-29(36-14)41-23-7-4-17(10-21(23)32)24-25(27(33)39)22-12-35-15(2)13-38(22)26(24)19-6-5-18(11-20(19)31)37-28(40)16(3)30/h4-13H,3H2,1-2H3,(H2,33,39)(H,37,40)	RURRVXKJQUSIDS-UHFFFAOYSA-N	75489	US20250382297, Example 43	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75489	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75489&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			4983475	252652696							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120576	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)c(F)c1	InChI=1S/C29H21F3N6O3/c1-14-8-9-34-29(36-14)41-23-7-4-17(10-21(23)32)24-25(27(33)39)22-12-35-15(2)13-38(22)26(24)19-6-5-18(11-20(19)31)37-28(40)16(3)30/h4-13H,3H2,1-2H3,(H2,33,39)(H,37,40)	RURRVXKJQUSIDS-UHFFFAOYSA-N	75489	US20250382297, Example 43	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75489	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75489&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			4983475	252652696							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120577	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)c(F)c1	InChI=1S/C29H21F3N6O3/c1-14-8-9-34-29(36-14)41-23-7-4-17(10-21(23)32)24-25(27(33)39)22-12-35-15(2)13-38(22)26(24)19-6-5-18(11-20(19)31)37-28(40)16(3)30/h4-13H,3H2,1-2H3,(H2,33,39)(H,37,40)	RURRVXKJQUSIDS-UHFFFAOYSA-N	75489	US20250382297, Example 43	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75489	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75489&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			4983475	252652696							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120578	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3C)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H25FN6O3/c1-16-13-22(40-30-33-12-11-17(2)35-30)9-10-23(16)25-26(28(32)38)24-14-34-18(3)15-37(24)27(25)20-5-7-21(8-6-20)36-29(39)19(4)31/h5-15H,4H2,1-3H3,(H2,32,38)(H,36,39)	CPDJMILOUHAJOK-UHFFFAOYSA-N	75490	US20250382297, Example 44	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75490	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75490&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2916909	252652697							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120579	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3C)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H25FN6O3/c1-16-13-22(40-30-33-12-11-17(2)35-30)9-10-23(16)25-26(28(32)38)24-14-34-18(3)15-37(24)27(25)20-5-7-21(8-6-20)36-29(39)19(4)31/h5-15H,4H2,1-3H3,(H2,32,38)(H,36,39)	CPDJMILOUHAJOK-UHFFFAOYSA-N	75490	US20250382297, Example 44	Fibroblast growth factor receptor 2	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75490	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75490&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2916909	252652697							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120580	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3C)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H25FN6O3/c1-16-13-22(40-30-33-12-11-17(2)35-30)9-10-23(16)25-26(28(32)38)24-14-34-18(3)15-37(24)27(25)20-5-7-21(8-6-20)36-29(39)19(4)31/h5-15H,4H2,1-3H3,(H2,32,38)(H,36,39)	CPDJMILOUHAJOK-UHFFFAOYSA-N	75490	US20250382297, Example 44	Fibroblast growth factor receptor 3	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75490	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75490&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2916909	252652697							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120581	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3F)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-10-11-33-29(35-15)40-20-8-9-21(22(31)12-20)24-25(27(32)38)23-13-34-16(2)14-37(23)26(24)18-4-6-19(7-5-18)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	JMKFFZBSDAXBST-UHFFFAOYSA-N	75491	US20250382297, Example 45	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75491	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75491&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			850357	252652698							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120582	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3F)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-10-11-33-29(35-15)40-20-8-9-21(22(31)12-20)24-25(27(32)38)23-13-34-16(2)14-37(23)26(24)18-4-6-19(7-5-18)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	JMKFFZBSDAXBST-UHFFFAOYSA-N	75491	US20250382297, Example 45	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75491	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75491&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			850357	252652698							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120583	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3F)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-10-11-33-29(35-15)40-20-8-9-21(22(31)12-20)24-25(27(32)38)23-13-34-16(2)14-37(23)26(24)18-4-6-19(7-5-18)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	JMKFFZBSDAXBST-UHFFFAOYSA-N	75491	US20250382297, Example 45	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75491	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75491&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			850357	252652698							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120584	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(OC)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H25FN6O4/c1-16-11-12-33-30(35-16)41-23-10-7-20(13-24(23)40-4)25-26(28(32)38)22-14-34-17(2)15-37(22)27(25)19-5-8-21(9-6-19)36-29(39)18(3)31/h5-15H,3H2,1-2,4H3,(H2,32,38)(H,36,39)	KGAVVKIJLQDWHK-UHFFFAOYSA-N	75492	US20250382297, Example 46	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75492	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75492&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			11840027	252652699							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120585	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(OC)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H25FN6O4/c1-16-11-12-33-30(35-16)41-23-10-7-20(13-24(23)40-4)25-26(28(32)38)22-14-34-17(2)15-37(22)27(25)19-5-8-21(9-6-19)36-29(39)18(3)31/h5-15H,3H2,1-2,4H3,(H2,32,38)(H,36,39)	KGAVVKIJLQDWHK-UHFFFAOYSA-N	75492	US20250382297, Example 46	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75492	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75492&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			11840027	252652699							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120586	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(OC)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H25FN6O4/c1-16-11-12-33-30(35-16)41-23-10-7-20(13-24(23)40-4)25-26(28(32)38)22-14-34-17(2)15-37(22)27(25)19-5-8-21(9-6-19)36-29(39)18(3)31/h5-15H,3H2,1-2,4H3,(H2,32,38)(H,36,39)	KGAVVKIJLQDWHK-UHFFFAOYSA-N	75492	US20250382297, Example 46	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75492	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75492&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			11840027	252652699							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120587	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1F	InChI=1S/C29H21F3N6O3/c1-14-8-9-34-29(36-14)41-23-7-5-17(10-20(23)32)24-25(27(33)39)22-12-35-15(2)13-38(22)26(24)18-4-6-21(19(31)11-18)37-28(40)16(3)30/h4-13H,3H2,1-2H3,(H2,33,39)(H,37,40)	YBQOSQZXYHLLMX-UHFFFAOYSA-N	75493	US20250382297, Example 47	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75493	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75493&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			6948449	252652700							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120588	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1F	InChI=1S/C29H21F3N6O3/c1-14-8-9-34-29(36-14)41-23-7-5-17(10-20(23)32)24-25(27(33)39)22-12-35-15(2)13-38(22)26(24)18-4-6-21(19(31)11-18)37-28(40)16(3)30/h4-13H,3H2,1-2H3,(H2,33,39)(H,37,40)	YBQOSQZXYHLLMX-UHFFFAOYSA-N	75493	US20250382297, Example 47	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75493	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75493&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			6948449	252652700							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120589	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1F	InChI=1S/C29H21F3N6O3/c1-14-8-9-34-29(36-14)41-23-7-5-17(10-20(23)32)24-25(27(33)39)22-12-35-15(2)13-38(22)26(24)18-4-6-21(19(31)11-18)37-28(40)16(3)30/h4-13H,3H2,1-2H3,(H2,33,39)(H,37,40)	YBQOSQZXYHLLMX-UHFFFAOYSA-N	75493	US20250382297, Example 47	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75493	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75493&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			6948449	252652700							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120590	C=C(F)C(=O)Nc1ccc(-c2c(-c3cc(F)c(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H21F3N6O3/c1-14-8-9-34-29(36-14)41-26-20(31)10-18(11-21(26)32)23-24(27(33)39)22-12-35-15(2)13-38(22)25(23)17-4-6-19(7-5-17)37-28(40)16(3)30/h4-13H,3H2,1-2H3,(H2,33,39)(H,37,40)	JDPFFIFJPBLMEP-UHFFFAOYSA-N	75494	US20250382297, Example 48	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75494	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75494&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			710605	252652701							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120591	C=C(F)C(=O)Nc1ccc(-c2c(-c3cc(F)c(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H21F3N6O3/c1-14-8-9-34-29(36-14)41-26-20(31)10-18(11-21(26)32)23-24(27(33)39)22-12-35-15(2)13-38(22)25(23)17-4-6-19(7-5-17)37-28(40)16(3)30/h4-13H,3H2,1-2H3,(H2,33,39)(H,37,40)	JDPFFIFJPBLMEP-UHFFFAOYSA-N	75494	US20250382297, Example 48	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75494	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75494&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			710605	252652701							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120592	C=C(F)C(=O)Nc1ccc(-c2c(-c3cc(F)c(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H21F3N6O3/c1-14-8-9-34-29(36-14)41-26-20(31)10-18(11-21(26)32)23-24(27(33)39)22-12-35-15(2)13-38(22)25(23)17-4-6-19(7-5-17)37-28(40)16(3)30/h4-13H,3H2,1-2H3,(H2,33,39)(H,37,40)	JDPFFIFJPBLMEP-UHFFFAOYSA-N	75494	US20250382297, Example 48	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75494	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75494&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			710605	252652701							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120593	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)c(C)c1	InChI=1S/C30H24F2N6O3/c1-15-11-20(37-29(40)18(4)31)6-7-21(15)27-25(26(28(33)39)23-13-35-17(3)14-38(23)27)19-5-8-24(22(32)12-19)41-30-34-10-9-16(2)36-30/h5-14H,4H2,1-3H3,(H2,33,39)(H,37,40)	DIESVRDKKPTCJG-UHFFFAOYSA-N	75495	US20250382297, Example 49	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75495	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75495&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			901941	252652702							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120594	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)c(C)c1	InChI=1S/C30H24F2N6O3/c1-15-11-20(37-29(40)18(4)31)6-7-21(15)27-25(26(28(33)39)23-13-35-17(3)14-38(23)27)19-5-8-24(22(32)12-19)41-30-34-10-9-16(2)36-30/h5-14H,4H2,1-3H3,(H2,33,39)(H,37,40)	DIESVRDKKPTCJG-UHFFFAOYSA-N	75495	US20250382297, Example 49	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75495	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75495&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			901941	252652702							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120595	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)c(C)c1	InChI=1S/C30H24F2N6O3/c1-15-11-20(37-29(40)18(4)31)6-7-21(15)27-25(26(28(33)39)23-13-35-17(3)14-38(23)27)19-5-8-24(22(32)12-19)41-30-34-10-9-16(2)36-30/h5-14H,4H2,1-3H3,(H2,33,39)(H,37,40)	DIESVRDKKPTCJG-UHFFFAOYSA-N	75495	US20250382297, Example 49	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75495	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75495&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			901941	252652702							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120596	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)nc1	InChI=1S/C28H22FN7O3/c1-15-10-11-31-28(34-15)39-20-7-4-18(5-8-20)23-24(26(30)37)22-13-32-16(2)14-36(22)25(23)21-9-6-19(12-33-21)35-27(38)17(3)29/h4-14H,3H2,1-2H3,(H2,30,37)(H,35,38)	DTQKEWPWQCXAKY-UHFFFAOYSA-N	75496	6-(5-(2-fluoroacrylamido)pyridin-2-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 50	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75496	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75496&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			883409	252652703							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120597	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)nc1	InChI=1S/C28H22FN7O3/c1-15-10-11-31-28(34-15)39-20-7-4-18(5-8-20)23-24(26(30)37)22-13-32-16(2)14-36(22)25(23)21-9-6-19(12-33-21)35-27(38)17(3)29/h4-14H,3H2,1-2H3,(H2,30,37)(H,35,38)	DTQKEWPWQCXAKY-UHFFFAOYSA-N	75496	6-(5-(2-fluoroacrylamido)pyridin-2-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 50	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75496	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75496&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			883409	252652703							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120598	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)nc1	InChI=1S/C28H22FN7O3/c1-15-10-11-31-28(34-15)39-20-7-4-18(5-8-20)23-24(26(30)37)22-13-32-16(2)14-36(22)25(23)21-9-6-19(12-33-21)35-27(38)17(3)29/h4-14H,3H2,1-2H3,(H2,30,37)(H,35,38)	DTQKEWPWQCXAKY-UHFFFAOYSA-N	75496	6-(5-(2-fluoroacrylamido)pyridin-2-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 50	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75496	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75496&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			883409	252652703							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120599	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cn1	InChI=1S/C28H21F2N7O3/c1-14-8-9-32-28(35-14)40-21-6-4-17(10-19(21)30)23-24(26(31)38)20-12-33-15(2)13-37(20)25(23)18-5-7-22(34-11-18)36-27(39)16(3)29/h4-13H,3H2,1-2H3,(H2,31,38)(H,34,36,39)	YASZZCGGQBEFDT-UHFFFAOYSA-N	75497	US20250382297, Example 51	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75497	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75497&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1345009	252652704							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120600	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cn1	InChI=1S/C28H21F2N7O3/c1-14-8-9-32-28(35-14)40-21-6-4-17(10-19(21)30)23-24(26(31)38)20-12-33-15(2)13-37(20)25(23)18-5-7-22(34-11-18)36-27(39)16(3)29/h4-13H,3H2,1-2H3,(H2,31,38)(H,34,36,39)	YASZZCGGQBEFDT-UHFFFAOYSA-N	75497	US20250382297, Example 51	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75497	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75497&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1345009	252652704							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120601	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cn1	InChI=1S/C28H21F2N7O3/c1-14-8-9-32-28(35-14)40-21-6-4-17(10-19(21)30)23-24(26(31)38)20-12-33-15(2)13-37(20)25(23)18-5-7-22(34-11-18)36-27(39)16(3)29/h4-13H,3H2,1-2H3,(H2,31,38)(H,34,36,39)	YASZZCGGQBEFDT-UHFFFAOYSA-N	75497	US20250382297, Example 51	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75497	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75497&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1345009	252652704							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120602	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4cc(C)ccn4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H24FN5O3/c1-17-12-13-33-25(14-17)39-23-10-6-20(7-11-23)26-27(29(32)37)24-15-34-18(2)16-36(24)28(26)21-4-8-22(9-5-21)35-30(38)19(3)31/h4-16H,3H2,1-2H3,(H2,32,37)(H,35,38)	LQSOAKSUJFXUSR-UHFFFAOYSA-N	75498	US20250382297, Example 52	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75498	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75498&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			9586767	252652705							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120603	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4cc(C)ccn4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H24FN5O3/c1-17-12-13-33-25(14-17)39-23-10-6-20(7-11-23)26-27(29(32)37)24-15-34-18(2)16-36(24)28(26)21-4-8-22(9-5-21)35-30(38)19(3)31/h4-16H,3H2,1-2H3,(H2,32,37)(H,35,38)	LQSOAKSUJFXUSR-UHFFFAOYSA-N	75498	US20250382297, Example 52	Fibroblast growth factor receptor 2	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75498	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75498&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			9586767	252652705							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120604	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4cc(C)ccn4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H24FN5O3/c1-17-12-13-33-25(14-17)39-23-10-6-20(7-11-23)26-27(29(32)37)24-15-34-18(2)16-36(24)28(26)21-4-8-22(9-5-21)35-30(38)19(3)31/h4-16H,3H2,1-2H3,(H2,32,37)(H,35,38)	LQSOAKSUJFXUSR-UHFFFAOYSA-N	75498	US20250382297, Example 52	Fibroblast growth factor receptor 3	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75498	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75498&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			9586767	252652705							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120605	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nc(C)cc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H24F2N6O3/c1-15-11-16(2)36-30(35-15)41-24-10-7-20(12-22(24)32)25-26(28(33)39)23-13-34-17(3)14-38(23)27(25)19-5-8-21(9-6-19)37-29(40)18(4)31/h5-14H,4H2,1-3H3,(H2,33,39)(H,37,40)	MMIUORIBTNLXHH-UHFFFAOYSA-N	75499	US20250382297, Example 53	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75499	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75499&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			808190	252652706							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120606	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nc(C)cc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H24F2N6O3/c1-15-11-16(2)36-30(35-15)41-24-10-7-20(12-22(24)32)25-26(28(33)39)23-13-34-17(3)14-38(23)27(25)19-5-8-21(9-6-19)37-29(40)18(4)31/h5-14H,4H2,1-3H3,(H2,33,39)(H,37,40)	MMIUORIBTNLXHH-UHFFFAOYSA-N	75499	US20250382297, Example 53	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75499	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75499&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			808190	252652706							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120607	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nc(C)cc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H24F2N6O3/c1-15-11-16(2)36-30(35-15)41-24-10-7-20(12-22(24)32)25-26(28(33)39)23-13-34-17(3)14-38(23)27(25)19-5-8-21(9-6-19)37-29(40)18(4)31/h5-14H,4H2,1-3H3,(H2,33,39)(H,37,40)	MMIUORIBTNLXHH-UHFFFAOYSA-N	75499	US20250382297, Example 53	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75499	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75499&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			808190	252652706							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120608	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4ncc(F)c(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H21F3N6O3/c1-14-13-38-22(12-34-14)25(27(33)39)24(26(38)17-4-7-19(8-5-17)37-28(40)15(2)30)18-6-9-23(20(31)10-18)41-29-35-11-21(32)16(3)36-29/h4-13H,2H2,1,3H3,(H2,33,39)(H,37,40)	QLYPWGWIAYDACJ-UHFFFAOYSA-N	75500	US20250382297, Example 54	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75500	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75500&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1088600	252652707							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120609	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4ncc(F)c(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H21F3N6O3/c1-14-13-38-22(12-34-14)25(27(33)39)24(26(38)17-4-7-19(8-5-17)37-28(40)15(2)30)18-6-9-23(20(31)10-18)41-29-35-11-21(32)16(3)36-29/h4-13H,2H2,1,3H3,(H2,33,39)(H,37,40)	QLYPWGWIAYDACJ-UHFFFAOYSA-N	75500	US20250382297, Example 54	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75500	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75500&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1088600	252652707							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120610	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4ncc(F)c(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H21F3N6O3/c1-14-13-38-22(12-34-14)25(27(33)39)24(26(38)17-4-7-19(8-5-17)37-28(40)15(2)30)18-6-9-23(20(31)10-18)41-29-35-11-21(32)16(3)36-29/h4-13H,2H2,1,3H3,(H2,33,39)(H,37,40)	QLYPWGWIAYDACJ-UHFFFAOYSA-N	75500	US20250382297, Example 54	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75500	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75500&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1088600	252652707							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120611	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)c(CO)c1	InChI=1S/C30H25FN6O4/c1-16-10-11-33-30(35-16)41-22-7-4-19(5-8-22)25-26(28(32)39)24-13-34-17(2)14-37(24)27(25)23-9-6-21(12-20(23)15-38)36-29(40)18(3)31/h4-14,38H,3,15H2,1-2H3,(H2,32,39)(H,36,40)	CSUFTNJBZLYBIU-UHFFFAOYSA-N	75501	US20250382297, Example 55	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75501	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75501&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1086050	252652708							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120612	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)c(CO)c1	InChI=1S/C30H25FN6O4/c1-16-10-11-33-30(35-16)41-22-7-4-19(5-8-22)25-26(28(32)39)24-13-34-17(2)14-37(24)27(25)23-9-6-21(12-20(23)15-38)36-29(40)18(3)31/h4-14,38H,3,15H2,1-2H3,(H2,32,39)(H,36,40)	CSUFTNJBZLYBIU-UHFFFAOYSA-N	75501	US20250382297, Example 55	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75501	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75501&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1086050	252652708							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120613	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)c(CO)c1	InChI=1S/C30H25FN6O4/c1-16-10-11-33-30(35-16)41-22-7-4-19(5-8-22)25-26(28(32)39)24-13-34-17(2)14-37(24)27(25)23-9-6-21(12-20(23)15-38)36-29(40)18(3)31/h4-14,38H,3,15H2,1-2H3,(H2,32,39)(H,36,40)	CSUFTNJBZLYBIU-UHFFFAOYSA-N	75501	US20250382297, Example 55	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75501	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75501&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1086050	252652708							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120614	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C(F)(F)F)cn23)cc1	InChI=1S/C29H20F4N6O3/c1-15-11-12-35-28(37-15)42-20-9-5-17(6-10-20)23-24(26(34)40)21-13-36-22(29(31,32)33)14-39(21)25(23)18-3-7-19(8-4-18)38-27(41)16(2)30/h3-14H,2H2,1H3,(H2,34,40)(H,38,41)	MNWLJRNAYDDUEQ-UHFFFAOYSA-N	75502	US20250382297, Example 56	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75502	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75502&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			16194515	252652709							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120615	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C(F)(F)F)cn23)cc1	InChI=1S/C29H20F4N6O3/c1-15-11-12-35-28(37-15)42-20-9-5-17(6-10-20)23-24(26(34)40)21-13-36-22(29(31,32)33)14-39(21)25(23)18-3-7-19(8-4-18)38-27(41)16(2)30/h3-14H,2H2,1H3,(H2,34,40)(H,38,41)	MNWLJRNAYDDUEQ-UHFFFAOYSA-N	75502	US20250382297, Example 56	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75502	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75502&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			16194515	252652709							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120616	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C(F)(F)F)cn23)cc1	InChI=1S/C29H20F4N6O3/c1-15-11-12-35-28(37-15)42-20-9-5-17(6-10-20)23-24(26(34)40)21-13-36-22(29(31,32)33)14-39(21)25(23)18-3-7-19(8-4-18)38-27(41)16(2)30/h3-14H,2H2,1H3,(H2,34,40)(H,38,41)	MNWLJRNAYDDUEQ-UHFFFAOYSA-N	75502	US20250382297, Example 56	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75502	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75502&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			16194515	252652709							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120617	Cc1cn2c(-c3ccc(NC(=O)/C=C/CN(C)C)cc3)c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c2cn1	InChI=1S/C32H31N7O3/c1-20-15-16-34-32(36-20)42-25-13-9-22(10-14-25)28-29(31(33)41)26-18-35-21(2)19-39(26)30(28)23-7-11-24(12-8-23)37-27(40)6-5-17-38(3)4/h5-16,18-19H,17H2,1-4H3,(H2,33,41)(H,37,40)	DHCIGYZFMPCQCB-UHFFFAOYSA-N	75503	(E)-6-(4-(4-(dimethylamino) but-2-enamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::(E)-6-(4-(4-(dimethylamino)but-2-enamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 57	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75503&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			7087668	252652710							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120618	Cc1cn2c(-c3ccc(NC(=O)/C=C/CN(C)C)cc3)c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c2cn1	InChI=1S/C32H31N7O3/c1-20-15-16-34-32(36-20)42-25-13-9-22(10-14-25)28-29(31(33)41)26-18-35-21(2)19-39(26)30(28)23-7-11-24(12-8-23)37-27(40)6-5-17-38(3)4/h5-16,18-19H,17H2,1-4H3,(H2,33,41)(H,37,40)	DHCIGYZFMPCQCB-UHFFFAOYSA-N	75503	(E)-6-(4-(4-(dimethylamino) but-2-enamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::(E)-6-(4-(4-(dimethylamino)but-2-enamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 57	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75503&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			7087668	252652710							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120619	Cc1cn2c(-c3ccc(NC(=O)/C=C/CN(C)C)cc3)c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c2cn1	InChI=1S/C32H31N7O3/c1-20-15-16-34-32(36-20)42-25-13-9-22(10-14-25)28-29(31(33)41)26-18-35-21(2)19-39(26)30(28)23-7-11-24(12-8-23)37-27(40)6-5-17-38(3)4/h5-16,18-19H,17H2,1-4H3,(H2,33,41)(H,37,40)	DHCIGYZFMPCQCB-UHFFFAOYSA-N	75503	(E)-6-(4-(4-(dimethylamino) but-2-enamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::(E)-6-(4-(4-(dimethylamino)but-2-enamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 57	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75503&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			7087668	252652710							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120620	C=C(CO)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H26N6O4/c1-17(16-37)29(39)35-22-8-4-21(5-9-22)27-25(26(28(31)38)24-14-33-19(3)15-36(24)27)20-6-10-23(11-7-20)40-30-32-13-12-18(2)34-30/h4-15,37H,1,16H2,2-3H3,(H2,31,38)(H,35,39)	JKPHCDRMSMNXQA-UHFFFAOYSA-N	75504	6-(4-(2-(hydroxymethyl) acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(2-(hydroxymethyl)acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 58	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75504	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75504&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1473716	252652711							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120621	C=C(CO)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H26N6O4/c1-17(16-37)29(39)35-22-8-4-21(5-9-22)27-25(26(28(31)38)24-14-33-19(3)15-36(24)27)20-6-10-23(11-7-20)40-30-32-13-12-18(2)34-30/h4-15,37H,1,16H2,2-3H3,(H2,31,38)(H,35,39)	JKPHCDRMSMNXQA-UHFFFAOYSA-N	75504	6-(4-(2-(hydroxymethyl) acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(2-(hydroxymethyl)acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 58	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75504	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75504&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1473716	252652711							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120622	C=C(CO)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H26N6O4/c1-17(16-37)29(39)35-22-8-4-21(5-9-22)27-25(26(28(31)38)24-14-33-19(3)15-36(24)27)20-6-10-23(11-7-20)40-30-32-13-12-18(2)34-30/h4-15,37H,1,16H2,2-3H3,(H2,31,38)(H,35,39)	JKPHCDRMSMNXQA-UHFFFAOYSA-N	75504	6-(4-(2-(hydroxymethyl) acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(2-(hydroxymethyl)acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 58	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75504	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75504&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1473716	252652711							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120623	C=C(CN(C)C)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C32H31N7O3/c1-19(17-38(4)5)31(41)37-24-10-6-23(7-11-24)29-27(28(30(33)40)26-16-35-21(3)18-39(26)29)22-8-12-25(13-9-22)42-32-34-15-14-20(2)36-32/h6-16,18H,1,17H2,2-5H3,(H2,33,40)(H,37,41)	FKZZXEUKQOFTAD-UHFFFAOYSA-N	75505	6-(4-(2-((dimethylamino)methyl) acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(2-((dimethylamino)methyl)acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 59	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75505	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75505&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1475595	252652712							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120624	C=C(CN(C)C)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C32H31N7O3/c1-19(17-38(4)5)31(41)37-24-10-6-23(7-11-24)29-27(28(30(33)40)26-16-35-21(3)18-39(26)29)22-8-12-25(13-9-22)42-32-34-15-14-20(2)36-32/h6-16,18H,1,17H2,2-5H3,(H2,33,40)(H,37,41)	FKZZXEUKQOFTAD-UHFFFAOYSA-N	75505	6-(4-(2-((dimethylamino)methyl) acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(2-((dimethylamino)methyl)acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 59	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75505	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75505&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1475595	252652712							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120625	C=C(CN(C)C)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C32H31N7O3/c1-19(17-38(4)5)31(41)37-24-10-6-23(7-11-24)29-27(28(30(33)40)26-16-35-21(3)18-39(26)29)22-8-12-25(13-9-22)42-32-34-15-14-20(2)36-32/h6-16,18H,1,17H2,2-5H3,(H2,33,40)(H,37,41)	FKZZXEUKQOFTAD-UHFFFAOYSA-N	75505	6-(4-(2-((dimethylamino)methyl) acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(2-((dimethylamino)methyl)acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 59	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75505	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75505&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1475595	252652712							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120626	C=C(COC)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C31H28N6O4/c1-18(17-40-4)30(39)36-23-9-5-22(6-10-23)28-26(27(29(32)38)25-15-34-20(3)16-37(25)28)21-7-11-24(12-8-21)41-31-33-14-13-19(2)35-31/h5-16H,1,17H2,2-4H3,(H2,32,38)(H,36,39)	XGLCIUBPXXLOCE-UHFFFAOYSA-N	75506	6-(4-(2-(methoxymethyl) acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(2-(methoxymethyl)acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 60	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75506	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75506&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			7190888	252652713							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120627	C=C(COC)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C31H28N6O4/c1-18(17-40-4)30(39)36-23-9-5-22(6-10-23)28-26(27(29(32)38)25-15-34-20(3)16-37(25)28)21-7-11-24(12-8-21)41-31-33-14-13-19(2)35-31/h5-16H,1,17H2,2-4H3,(H2,32,38)(H,36,39)	XGLCIUBPXXLOCE-UHFFFAOYSA-N	75506	6-(4-(2-(methoxymethyl) acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(2-(methoxymethyl)acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 60	Fibroblast growth factor receptor 2	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75506	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75506&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			7190888	252652713							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120628	C=C(COC)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C31H28N6O4/c1-18(17-40-4)30(39)36-23-9-5-22(6-10-23)28-26(27(29(32)38)25-15-34-20(3)16-37(25)28)21-7-11-24(12-8-21)41-31-33-14-13-19(2)35-31/h5-16H,1,17H2,2-4H3,(H2,32,38)(H,36,39)	XGLCIUBPXXLOCE-UHFFFAOYSA-N	75506	6-(4-(2-(methoxymethyl) acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(2-(methoxymethyl)acrylamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 60	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75506	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75506&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			7190888	252652713							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120629	Cc1cn2c(-c3ccc(NC(=O)/C=C/C4CCCN4C)cc3)c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c2cn1	InChI=1S/C34H33N7O3/c1-21-16-17-36-34(38-21)44-27-13-8-23(9-14-27)30-31(33(35)43)28-19-37-22(2)20-41(28)32(30)24-6-10-25(11-7-24)39-29(42)15-12-26-5-4-18-40(26)3/h6-17,19-20,26H,4-5,18H2,1-3H3,(H2,35,43)(H,39,42)	DRXKQLNJYIVESN-UHFFFAOYSA-N	75507	(E)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(4-(3-(1-methylpyrrolidin-2-yl) acrylamido)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::(E)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(4-(3-(1-methylpyrrolidin-2-yl)acrylamido)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 61	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75507	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75507&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			9648844	252652714							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120630	Cc1cn2c(-c3ccc(NC(=O)/C=C/C4CCCN4C)cc3)c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c2cn1	InChI=1S/C34H33N7O3/c1-21-16-17-36-34(38-21)44-27-13-8-23(9-14-27)30-31(33(35)43)28-19-37-22(2)20-41(28)32(30)24-6-10-25(11-7-24)39-29(42)15-12-26-5-4-18-40(26)3/h6-17,19-20,26H,4-5,18H2,1-3H3,(H2,35,43)(H,39,42)	DRXKQLNJYIVESN-UHFFFAOYSA-N	75507	(E)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(4-(3-(1-methylpyrrolidin-2-yl) acrylamido)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::(E)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(4-(3-(1-methylpyrrolidin-2-yl)acrylamido)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 61	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75507	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75507&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			9648844	252652714							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120631	Cc1cn2c(-c3ccc(NC(=O)/C=C/C4CCCN4C)cc3)c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c2cn1	InChI=1S/C34H33N7O3/c1-21-16-17-36-34(38-21)44-27-13-8-23(9-14-27)30-31(33(35)43)28-19-37-22(2)20-41(28)32(30)24-6-10-25(11-7-24)39-29(42)15-12-26-5-4-18-40(26)3/h6-17,19-20,26H,4-5,18H2,1-3H3,(H2,35,43)(H,39,42)	DRXKQLNJYIVESN-UHFFFAOYSA-N	75507	(E)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(4-(3-(1-methylpyrrolidin-2-yl) acrylamido)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::(E)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(4-(3-(1-methylpyrrolidin-2-yl)acrylamido)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 61	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75507	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75507&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			9648844	252652714							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120632	CC#CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H24N6O3/c1-4-5-25(37)35-22-10-6-21(7-11-22)28-26(27(29(31)38)24-16-33-19(3)17-36(24)28)20-8-12-23(13-9-20)39-30-32-15-14-18(2)34-30/h6-17H,1-3H3,(H2,31,38)(H,35,37)	XPOBVUCONZXHRQ-UHFFFAOYSA-N	75508	6-(4-(but-2-ynamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 62	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75508	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75508&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			5148266	252652715							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120633	CC#CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H24N6O3/c1-4-5-25(37)35-22-10-6-21(7-11-22)28-26(27(29(31)38)24-16-33-19(3)17-36(24)28)20-8-12-23(13-9-20)39-30-32-15-14-18(2)34-30/h6-17H,1-3H3,(H2,31,38)(H,35,37)	XPOBVUCONZXHRQ-UHFFFAOYSA-N	75508	6-(4-(but-2-ynamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 62	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75508	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75508&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			5148266	252652715							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120634	CC#CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H24N6O3/c1-4-5-25(37)35-22-10-6-21(7-11-22)28-26(27(29(31)38)24-16-33-19(3)17-36(24)28)20-8-12-23(13-9-20)39-30-32-15-14-18(2)34-30/h6-17H,1-3H3,(H2,31,38)(H,35,37)	XPOBVUCONZXHRQ-UHFFFAOYSA-N	75508	6-(4-(but-2-ynamido)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 62	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75508	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75508&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			5148266	252652715							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120635	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)COC4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H25F2N5O4/c1-16-12-36-22(11-33-16)24(26(32)37)23(25(36)19-7-9-21(10-8-19)35-27(38)17(2)30)18-3-5-20(6-4-18)28(39)34-13-29(31)14-40-15-29/h3-12H,2,13-15H2,1H3,(H2,32,37)(H,34,39)(H,35,38)	GGNSLEJJGGUQEO-UHFFFAOYSA-N	75509	6-(4-(2-fluoroacrylamido)phenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl) carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(2-fluoroacrylamido)phenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl)carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 63	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75509	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75509&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			16244870	252652716							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120636	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)COC4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H25F2N5O4/c1-16-12-36-22(11-33-16)24(26(32)37)23(25(36)19-7-9-21(10-8-19)35-27(38)17(2)30)18-3-5-20(6-4-18)28(39)34-13-29(31)14-40-15-29/h3-12H,2,13-15H2,1H3,(H2,32,37)(H,34,39)(H,35,38)	GGNSLEJJGGUQEO-UHFFFAOYSA-N	75509	6-(4-(2-fluoroacrylamido)phenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl) carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(2-fluoroacrylamido)phenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl)carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 63	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75509	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75509&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			16244870	252652716							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120637	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)COC4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H25F2N5O4/c1-16-12-36-22(11-33-16)24(26(32)37)23(25(36)19-7-9-21(10-8-19)35-27(38)17(2)30)18-3-5-20(6-4-18)28(39)34-13-29(31)14-40-15-29/h3-12H,2,13-15H2,1H3,(H2,32,37)(H,34,39)(H,35,38)	GGNSLEJJGGUQEO-UHFFFAOYSA-N	75509	6-(4-(2-fluoroacrylamido)phenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl) carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(2-fluoroacrylamido)phenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl)carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 63	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75509	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75509&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			16244870	252652716							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120638	C=CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)COC4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H26FN5O4/c1-3-23(36)34-21-10-8-19(9-11-21)26-24(25(27(31)37)22-12-32-17(2)13-35(22)26)18-4-6-20(7-5-18)28(38)33-14-29(30)15-39-16-29/h3-13H,1,14-16H2,2H3,(H2,31,37)(H,33,38)(H,34,36)	QJKNBWUBBTZLAW-UHFFFAOYSA-N	75510	6-(4-acrylamidophenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl) carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-acrylamidophenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl)carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 64	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75510	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75510&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			3769533	252652717							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120639	C=CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)COC4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H26FN5O4/c1-3-23(36)34-21-10-8-19(9-11-21)26-24(25(27(31)37)22-12-32-17(2)13-35(22)26)18-4-6-20(7-5-18)28(38)33-14-29(30)15-39-16-29/h3-13H,1,14-16H2,2H3,(H2,31,37)(H,33,38)(H,34,36)	QJKNBWUBBTZLAW-UHFFFAOYSA-N	75510	6-(4-acrylamidophenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl) carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-acrylamidophenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl)carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 64	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75510	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75510&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			3769533	252652717							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120640	C=CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)COC4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C29H26FN5O4/c1-3-23(36)34-21-10-8-19(9-11-21)26-24(25(27(31)37)22-12-32-17(2)13-35(22)26)18-4-6-20(7-5-18)28(38)33-14-29(30)15-39-16-29/h3-13H,1,14-16H2,2H3,(H2,31,37)(H,33,38)(H,34,36)	QJKNBWUBBTZLAW-UHFFFAOYSA-N	75510	6-(4-acrylamidophenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl) carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-acrylamidophenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl)carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 64	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75510	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75510&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			3769533	252652717							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120641	CC#CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)COC4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H26FN5O4/c1-3-4-24(37)35-22-11-9-20(10-12-22)27-25(26(28(32)38)23-13-33-18(2)14-36(23)27)19-5-7-21(8-6-19)29(39)34-15-30(31)16-40-17-30/h5-14H,15-17H2,1-2H3,(H2,32,38)(H,34,39)(H,35,37)	WYZQOYSEOLRWDI-UHFFFAOYSA-N	75511	6-(4-(but-2-ynamido)phenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl) carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(but-2-ynamido)phenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl)carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 65	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75511	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75511&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			850250	252652718							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120642	CC#CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)COC4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H26FN5O4/c1-3-4-24(37)35-22-11-9-20(10-12-22)27-25(26(28(32)38)23-13-33-18(2)14-36(23)27)19-5-7-21(8-6-19)29(39)34-15-30(31)16-40-17-30/h5-14H,15-17H2,1-2H3,(H2,32,38)(H,34,39)(H,35,37)	WYZQOYSEOLRWDI-UHFFFAOYSA-N	75511	6-(4-(but-2-ynamido)phenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl) carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(but-2-ynamido)phenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl)carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 65	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75511	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75511&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			850250	252652718							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120643	CC#CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)COC4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1	InChI=1S/C30H26FN5O4/c1-3-4-24(37)35-22-11-9-20(10-12-22)27-25(26(28(32)38)23-13-33-18(2)14-36(23)27)19-5-7-21(8-6-19)29(39)34-15-30(31)16-40-17-30/h5-14H,15-17H2,1-2H3,(H2,32,38)(H,34,39)(H,35,37)	WYZQOYSEOLRWDI-UHFFFAOYSA-N	75511	6-(4-(but-2-ynamido)phenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl) carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-(but-2-ynamido)phenyl)-7-(4-(((3-fluorooxetan-3-yl)methyl)carbamoyl)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 65	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75511	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75511&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			850250	252652718							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120644	C#Cc1nc2ccc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)cc2n1C	InChI=1S/C30H23N7O2/c1-5-25-35-22-11-8-20(14-23(22)36(25)4)28-26(27(29(31)38)24-15-33-18(3)16-37(24)28)19-6-9-21(10-7-19)39-30-32-13-12-17(2)34-30/h1,6-16H,2-4H3,(H2,31,38)	IRVKEKGGXODNTP-UHFFFAOYSA-N	75512	6-(2-ethynyl-1-methyl-1H-benzo[d]imidazol-6-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 66	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75512	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75512&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2207821	252652719							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120645	C#Cc1nc2ccc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)cc2n1C	InChI=1S/C30H23N7O2/c1-5-25-35-22-11-8-20(14-23(22)36(25)4)28-26(27(29(31)38)24-15-33-18(3)16-37(24)28)19-6-9-21(10-7-19)39-30-32-13-12-17(2)34-30/h1,6-16H,2-4H3,(H2,31,38)	IRVKEKGGXODNTP-UHFFFAOYSA-N	75512	6-(2-ethynyl-1-methyl-1H-benzo[d]imidazol-6-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 66	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75512	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75512&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2207821	252652719							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120646	C#Cc1nc2ccc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)cc2n1C	InChI=1S/C30H23N7O2/c1-5-25-35-22-11-8-20(14-23(22)36(25)4)28-26(27(29(31)38)24-15-33-18(3)16-37(24)28)19-6-9-21(10-7-19)39-30-32-13-12-17(2)34-30/h1,6-16H,2-4H3,(H2,31,38)	IRVKEKGGXODNTP-UHFFFAOYSA-N	75512	6-(2-ethynyl-1-methyl-1H-benzo[d]imidazol-6-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 66	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75512	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75512&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2207821	252652719							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120647	CC#Cc1nc2ccc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)cc2n1C	InChI=1S/C31H25N7O2/c1-5-6-26-36-23-12-9-21(15-24(23)37(26)4)29-27(28(30(32)39)25-16-34-19(3)17-38(25)29)20-7-10-22(11-8-20)40-31-33-14-13-18(2)35-31/h7-17H,1-4H3,(H2,32,39)	LXKDWERIJGQSHI-UHFFFAOYSA-N	75513	3-methyl-6-(1-methyl-2-(prop-1-yn-1-yl)-1H-benzo[d]imidazol-6-yl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 67	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75513	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75513&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			790572	252652720							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120648	CC#Cc1nc2ccc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)cc2n1C	InChI=1S/C31H25N7O2/c1-5-6-26-36-23-12-9-21(15-24(23)37(26)4)29-27(28(30(32)39)25-16-34-19(3)17-38(25)29)20-7-10-22(11-8-20)40-31-33-14-13-18(2)35-31/h7-17H,1-4H3,(H2,32,39)	LXKDWERIJGQSHI-UHFFFAOYSA-N	75513	3-methyl-6-(1-methyl-2-(prop-1-yn-1-yl)-1H-benzo[d]imidazol-6-yl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 67	Fibroblast growth factor receptor 2	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75513	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75513&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			790572	252652720							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120649	CC#Cc1nc2ccc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)cc2n1C	InChI=1S/C31H25N7O2/c1-5-6-26-36-23-12-9-21(15-24(23)37(26)4)29-27(28(30(32)39)25-16-34-19(3)17-38(25)29)20-7-10-22(11-8-20)40-31-33-14-13-18(2)35-31/h7-17H,1-4H3,(H2,32,39)	LXKDWERIJGQSHI-UHFFFAOYSA-N	75513	3-methyl-6-(1-methyl-2-(prop-1-yn-1-yl)-1H-benzo[d]imidazol-6-yl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 67	Fibroblast growth factor receptor 3	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75513	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75513&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			790572	252652720							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120650	C=CC(=O)N1CC(n2cc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)cn2)C1	InChI=1S/C29H26N8O3/c1-4-24(38)35-15-21(16-35)37-14-20(11-33-37)27-25(26(28(30)39)23-12-32-18(3)13-36(23)27)19-5-7-22(8-6-19)40-29-31-10-9-17(2)34-29/h4-14,21H,1,15-16H2,2-3H3,(H2,30,39)	SKRQZFUZIUOYER-UHFFFAOYSA-N	75514	6-(1-(1-acryloylazetidin-3-yl)-1H-pyrazol-4-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 68	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75514&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1369664	252652721							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120651	C=CC(=O)N1CC(n2cc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)cn2)C1	InChI=1S/C29H26N8O3/c1-4-24(38)35-15-21(16-35)37-14-20(11-33-37)27-25(26(28(30)39)23-12-32-18(3)13-36(23)27)19-5-7-22(8-6-19)40-29-31-10-9-17(2)34-29/h4-14,21H,1,15-16H2,2-3H3,(H2,30,39)	SKRQZFUZIUOYER-UHFFFAOYSA-N	75514	6-(1-(1-acryloylazetidin-3-yl)-1H-pyrazol-4-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 68	Fibroblast growth factor receptor 2	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75514&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1369664	252652721							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120652	C=CC(=O)N1CC(n2cc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)cn2)C1	InChI=1S/C29H26N8O3/c1-4-24(38)35-15-21(16-35)37-14-20(11-33-37)27-25(26(28(30)39)23-12-32-18(3)13-36(23)27)19-5-7-22(8-6-19)40-29-31-10-9-17(2)34-29/h4-14,21H,1,15-16H2,2-3H3,(H2,30,39)	SKRQZFUZIUOYER-UHFFFAOYSA-N	75514	6-(1-(1-acryloylazetidin-3-yl)-1H-pyrazol-4-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 68	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75514&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1369664	252652721							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120653	C=CC(=O)N1CC(c2ccc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)cc2)C1	InChI=1S/C32H28N6O3/c1-4-27(39)37-17-24(18-37)21-5-7-23(8-6-21)30-28(29(31(33)40)26-15-35-20(3)16-38(26)30)22-9-11-25(12-10-22)41-32-34-14-13-19(2)36-32/h4-16,24H,1,17-18H2,2-3H3,(H2,33,40)	QIABKCPTXYNHDY-UHFFFAOYSA-N	75515	6-(4-(1-acryloylazetidin-3-yl)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 69	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75515	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75515&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			23724026	252652722							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120654	C=CC(=O)N1CC(c2ccc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)cc2)C1	InChI=1S/C32H28N6O3/c1-4-27(39)37-17-24(18-37)21-5-7-23(8-6-21)30-28(29(31(33)40)26-15-35-20(3)16-38(26)30)22-9-11-25(12-10-22)41-32-34-14-13-19(2)36-32/h4-16,24H,1,17-18H2,2-3H3,(H2,33,40)	QIABKCPTXYNHDY-UHFFFAOYSA-N	75515	6-(4-(1-acryloylazetidin-3-yl)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 69	Fibroblast growth factor receptor 2	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75515	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75515&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			23724026	252652722							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120655	C=CC(=O)N1CC(c2ccc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)cc2)C1	InChI=1S/C32H28N6O3/c1-4-27(39)37-17-24(18-37)21-5-7-23(8-6-21)30-28(29(31(33)40)26-15-35-20(3)16-38(26)30)22-9-11-25(12-10-22)41-32-34-14-13-19(2)36-32/h4-16,24H,1,17-18H2,2-3H3,(H2,33,40)	QIABKCPTXYNHDY-UHFFFAOYSA-N	75515	6-(4-(1-acryloylazetidin-3-yl)phenyl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 69	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75515	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75515&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			23724026	252652722							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120656	C=CC(=O)N1CC2(CC=C(c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)CC2)C1	InChI=1S/C31H30N6O3/c1-4-25(38)36-17-31(18-36)12-9-22(10-13-31)28-26(27(29(32)39)24-15-34-20(3)16-37(24)28)21-5-7-23(8-6-21)40-30-33-14-11-19(2)35-30/h4-9,11,14-16H,1,10,12-13,17-18H2,2-3H3,(H2,32,39)	WXRPHKXAQDMYRJ-UHFFFAOYSA-N	75516	6-(2-acryloyl-2-azaspiro[3.5]non-6-en-7-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 70	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75516&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			4619062	252652723							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120657	C=CC(=O)N1CC2(CC=C(c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)CC2)C1	InChI=1S/C31H30N6O3/c1-4-25(38)36-17-31(18-36)12-9-22(10-13-31)28-26(27(29(32)39)24-15-34-20(3)16-37(24)28)21-5-7-23(8-6-21)40-30-33-14-11-19(2)35-30/h4-9,11,14-16H,1,10,12-13,17-18H2,2-3H3,(H2,32,39)	WXRPHKXAQDMYRJ-UHFFFAOYSA-N	75516	6-(2-acryloyl-2-azaspiro[3.5]non-6-en-7-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 70	Fibroblast growth factor receptor 2	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75516&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			4619062	252652723							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120658	C=CC(=O)N1CC2(CC=C(c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)CC2)C1	InChI=1S/C31H30N6O3/c1-4-25(38)36-17-31(18-36)12-9-22(10-13-31)28-26(27(29(32)39)24-15-34-20(3)16-37(24)28)21-5-7-23(8-6-21)40-30-33-14-11-19(2)35-30/h4-9,11,14-16H,1,10,12-13,17-18H2,2-3H3,(H2,32,39)	WXRPHKXAQDMYRJ-UHFFFAOYSA-N	75516	6-(2-acryloyl-2-azaspiro[3.5]non-6-en-7-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 70	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75516&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			4619062	252652723							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120659	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)ccc21	InChI=1S/C31H25FN6O3/c1-17-10-12-34-31(36-17)41-23-7-4-20(5-8-23)26-27(29(33)39)25-15-35-18(2)16-38(25)28(26)22-6-9-24-21(14-22)11-13-37(24)30(40)19(3)32/h4-10,12,14-16H,3,11,13H2,1-2H3,(H2,33,39)	LHSUKKFHYTVMGP-UHFFFAOYSA-N	75517	6-(1-(2-fluoroacryloyl) indolin-5-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::6-(1-(2-fluoroacryloyl)indolin-5-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 71	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75517	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75517&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			3107863	252652724							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120660	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)ccc21	InChI=1S/C31H25FN6O3/c1-17-10-12-34-31(36-17)41-23-7-4-20(5-8-23)26-27(29(33)39)25-15-35-18(2)16-38(25)28(26)22-6-9-24-21(14-22)11-13-37(24)30(40)19(3)32/h4-10,12,14-16H,3,11,13H2,1-2H3,(H2,33,39)	LHSUKKFHYTVMGP-UHFFFAOYSA-N	75517	6-(1-(2-fluoroacryloyl) indolin-5-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::6-(1-(2-fluoroacryloyl)indolin-5-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 71	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75517	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75517&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			3107863	252652724							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120661	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)ccc21	InChI=1S/C31H25FN6O3/c1-17-10-12-34-31(36-17)41-23-7-4-20(5-8-23)26-27(29(33)39)25-15-35-18(2)16-38(25)28(26)22-6-9-24-21(14-22)11-13-37(24)30(40)19(3)32/h4-10,12,14-16H,3,11,13H2,1-2H3,(H2,33,39)	LHSUKKFHYTVMGP-UHFFFAOYSA-N	75517	6-(1-(2-fluoroacryloyl) indolin-5-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::6-(1-(2-fluoroacryloyl)indolin-5-yl)-3-methyl-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 71	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75517	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75517&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			3107863	252652724							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120662	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)ccc21	InChI=1S/C31H24F2N6O3/c1-16-8-10-35-31(37-16)42-25-7-5-20(13-22(25)33)26-27(29(34)40)24-14-36-17(2)15-39(24)28(26)21-4-6-23-19(12-21)9-11-38(23)30(41)18(3)32/h4-8,10,12-15H,3,9,11H2,1-2H3,(H2,34,40)	IEXNZPSNLAHQKK-UHFFFAOYSA-N	75518	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl) indolin-5-yl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl)indolin-5-yl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 72	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75518&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			91898141	252652725							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120663	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)ccc21	InChI=1S/C31H24F2N6O3/c1-16-8-10-35-31(37-16)42-25-7-5-20(13-22(25)33)26-27(29(34)40)24-14-36-17(2)15-39(24)28(26)21-4-6-23-19(12-21)9-11-38(23)30(41)18(3)32/h4-8,10,12-15H,3,9,11H2,1-2H3,(H2,34,40)	IEXNZPSNLAHQKK-UHFFFAOYSA-N	75518	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl) indolin-5-yl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl)indolin-5-yl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 72	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75518&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			91898141	252652725							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120664	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)ccc21	InChI=1S/C31H24F2N6O3/c1-16-8-10-35-31(37-16)42-25-7-5-20(13-22(25)33)26-27(29(34)40)24-14-36-17(2)15-39(24)28(26)21-4-6-23-19(12-21)9-11-38(23)30(41)18(3)32/h4-8,10,12-15H,3,9,11H2,1-2H3,(H2,34,40)	IEXNZPSNLAHQKK-UHFFFAOYSA-N	75518	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl) indolin-5-yl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl)indolin-5-yl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 72	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75518&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			91898141	252652725							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120665	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)c(F)cc21	InChI=1S/C31H23F3N6O3/c1-15-6-8-36-31(38-15)43-25-5-4-19(11-22(25)34)26-27(29(35)41)24-13-37-16(2)14-40(24)28(26)20-10-18-7-9-39(30(42)17(3)32)23(18)12-21(20)33/h4-6,8,10-14H,3,7,9H2,1-2H3,(H2,35,41)	UCFNWUZUTTWWJV-UHFFFAOYSA-N	75519	6-(6-fluoro-1-(2-fluoroacryloyl) indolin-5-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(6-fluoro-1-(2-fluoroacryloyl)indolin-5-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 73	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75519	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75519&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			693144	252652726							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120666	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)c(F)cc21	InChI=1S/C31H23F3N6O3/c1-15-6-8-36-31(38-15)43-25-5-4-19(11-22(25)34)26-27(29(35)41)24-13-37-16(2)14-40(24)28(26)20-10-18-7-9-39(30(42)17(3)32)23(18)12-21(20)33/h4-6,8,10-14H,3,7,9H2,1-2H3,(H2,35,41)	UCFNWUZUTTWWJV-UHFFFAOYSA-N	75519	6-(6-fluoro-1-(2-fluoroacryloyl) indolin-5-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(6-fluoro-1-(2-fluoroacryloyl)indolin-5-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 73	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75519	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75519&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			693144	252652726							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120667	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)c(F)cc21	InChI=1S/C31H23F3N6O3/c1-15-6-8-36-31(38-15)43-25-5-4-19(11-22(25)34)26-27(29(35)41)24-13-37-16(2)14-40(24)28(26)20-10-18-7-9-39(30(42)17(3)32)23(18)12-21(20)33/h4-6,8,10-14H,3,7,9H2,1-2H3,(H2,35,41)	UCFNWUZUTTWWJV-UHFFFAOYSA-N	75519	6-(6-fluoro-1-(2-fluoroacryloyl) indolin-5-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(6-fluoro-1-(2-fluoroacryloyl)indolin-5-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 73	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75519	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75519&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			693144	252652726							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120668	C=C(F)C(=O)Nc1ccc(-c2c(-c3cccc(C(=O)NC)c3)c(C(N)=O)c3cnc(C)cn23)c(F)c1	InChI=1S/C26H21F2N5O3/c1-13-12-33-20(11-31-13)22(24(29)34)21(15-5-4-6-16(9-15)26(36)30-3)23(33)18-8-7-17(10-19(18)28)32-25(35)14(2)27/h4-12H,2H2,1,3H3,(H2,29,34)(H,30,36)(H,32,35)	QYUZXKWYBVSENM-UHFFFAOYSA-N	75520	6-(2-fluoro-4-(2-fluoroacrylamido)phenyl)-3-methyl-7-(3-(methylcarbamoyl)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 75	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75520&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2938340	252652727							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120669	C=C(F)C(=O)Nc1ccc(-c2c(-c3cccc(C(=O)NC)c3)c(C(N)=O)c3cnc(C)cn23)c(F)c1	InChI=1S/C26H21F2N5O3/c1-13-12-33-20(11-31-13)22(24(29)34)21(15-5-4-6-16(9-15)26(36)30-3)23(33)18-8-7-17(10-19(18)28)32-25(35)14(2)27/h4-12H,2H2,1,3H3,(H2,29,34)(H,30,36)(H,32,35)	QYUZXKWYBVSENM-UHFFFAOYSA-N	75520	6-(2-fluoro-4-(2-fluoroacrylamido)phenyl)-3-methyl-7-(3-(methylcarbamoyl)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 75	Fibroblast growth factor receptor 2	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75520&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2938340	252652727							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120670	C=C(F)C(=O)Nc1ccc(-c2c(-c3cccc(C(=O)NC)c3)c(C(N)=O)c3cnc(C)cn23)c(F)c1	InChI=1S/C26H21F2N5O3/c1-13-12-33-20(11-31-13)22(24(29)34)21(15-5-4-6-16(9-15)26(36)30-3)23(33)18-8-7-17(10-19(18)28)32-25(35)14(2)27/h4-12H,2H2,1,3H3,(H2,29,34)(H,30,36)(H,32,35)	QYUZXKWYBVSENM-UHFFFAOYSA-N	75520	6-(2-fluoro-4-(2-fluoroacrylamido)phenyl)-3-methyl-7-(3-(methylcarbamoyl)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 75	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75520&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2938340	252652727							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120671	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C4COC4)cn23)cc1	InChI=1S/C32H27N5O4/c1-3-27(38)36-23-11-7-21(8-12-23)31-29(20-9-13-24(14-10-20)41-28-6-4-5-19(2)35-28)30(32(33)39)26-15-34-25(16-37(26)31)22-17-40-18-22/h3-16,22H,1,17-18H2,2H3,(H2,33,39)(H,36,38)	WCLBXERIYVDSQO-UHFFFAOYSA-N	75522	6-(4-acrylamidophenyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)-3-(oxetan-3-yl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 76	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75522&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			548037	252652729							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120672	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C4COC4)cn23)cc1	InChI=1S/C32H27N5O4/c1-3-27(38)36-23-11-7-21(8-12-23)31-29(20-9-13-24(14-10-20)41-28-6-4-5-19(2)35-28)30(32(33)39)26-15-34-25(16-37(26)31)22-17-40-18-22/h3-16,22H,1,17-18H2,2H3,(H2,33,39)(H,36,38)	WCLBXERIYVDSQO-UHFFFAOYSA-N	75522	6-(4-acrylamidophenyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)-3-(oxetan-3-yl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 76	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75522&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			548037	252652729							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120673	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C4COC4)cn23)cc1	InChI=1S/C32H27N5O4/c1-3-27(38)36-23-11-7-21(8-12-23)31-29(20-9-13-24(14-10-20)41-28-6-4-5-19(2)35-28)30(32(33)39)26-15-34-25(16-37(26)31)22-17-40-18-22/h3-16,22H,1,17-18H2,2H3,(H2,33,39)(H,36,38)	WCLBXERIYVDSQO-UHFFFAOYSA-N	75522	6-(4-acrylamidophenyl)-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)-3-(oxetan-3-yl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 76	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75522&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			548037	252652729							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120674	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C#N)cn23)cc1	InChI=1S/C30H22N6O3/c1-3-25(37)35-21-11-7-20(8-12-21)29-27(28(30(32)38)24-16-33-22(15-31)17-36(24)29)19-9-13-23(14-10-19)39-26-6-4-5-18(2)34-26/h3-14,16-17H,1H2,2H3,(H2,32,38)(H,35,37)	UQEWUTCFOTXNHU-UHFFFAOYSA-N	75524	6-(4-acrylamidophenyl)-3-cyano-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 77	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75524&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			91898142	252652731							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120675	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C#N)cn23)cc1	InChI=1S/C30H22N6O3/c1-3-25(37)35-21-11-7-20(8-12-21)29-27(28(30(32)38)24-16-33-22(15-31)17-36(24)29)19-9-13-23(14-10-19)39-26-6-4-5-18(2)34-26/h3-14,16-17H,1H2,2H3,(H2,32,38)(H,35,37)	UQEWUTCFOTXNHU-UHFFFAOYSA-N	75524	6-(4-acrylamidophenyl)-3-cyano-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 77	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75524&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			91898142	252652731							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120676	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C#N)cn23)cc1	InChI=1S/C30H22N6O3/c1-3-25(37)35-21-11-7-20(8-12-21)29-27(28(30(32)38)24-16-33-22(15-31)17-36(24)29)19-9-13-23(14-10-19)39-26-6-4-5-18(2)34-26/h3-14,16-17H,1H2,2H3,(H2,32,38)(H,35,37)	UQEWUTCFOTXNHU-UHFFFAOYSA-N	75524	6-(4-acrylamidophenyl)-3-cyano-7-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 77	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75524&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			91898142	252652731							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120677	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(CO)cn23)cc1	InChI=1S/C29H23FN6O4/c1-3-24(38)35-19-7-4-17(5-8-19)27-25(26(28(31)39)22-13-33-20(15-37)14-36(22)27)18-6-9-23(21(30)12-18)40-29-32-11-10-16(2)34-29/h3-14,37H,1,15H2,2H3,(H2,31,39)(H,35,38)	OZVQPIOBEYMHNM-UHFFFAOYSA-N	75525	6-(4-acrylamidophenyl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-(hydroxymethyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 78	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75525&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2834616	252652732							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120678	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(CO)cn23)cc1	InChI=1S/C29H23FN6O4/c1-3-24(38)35-19-7-4-17(5-8-19)27-25(26(28(31)39)22-13-33-20(15-37)14-36(22)27)18-6-9-23(21(30)12-18)40-29-32-11-10-16(2)34-29/h3-14,37H,1,15H2,2H3,(H2,31,39)(H,35,38)	OZVQPIOBEYMHNM-UHFFFAOYSA-N	75525	6-(4-acrylamidophenyl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-(hydroxymethyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 78	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75525&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2834616	252652732							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120679	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(CO)cn23)cc1	InChI=1S/C29H23FN6O4/c1-3-24(38)35-19-7-4-17(5-8-19)27-25(26(28(31)39)22-13-33-20(15-37)14-36(22)27)18-6-9-23(21(30)12-18)40-29-32-11-10-16(2)34-29/h3-14,37H,1,15H2,2H3,(H2,31,39)(H,35,38)	OZVQPIOBEYMHNM-UHFFFAOYSA-N	75525	6-(4-acrylamidophenyl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-(hydroxymethyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 78	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75525&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2834616	252652732							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120680	Cc1ccnc(Oc2ccc(-c3c(C(N)=O)c4cnc(CO)cn4c3-c3ccc(NC(=O)/C=C/CN(C)C)cc3)cc2)n1	InChI=1S/C32H31N7O4/c1-20-14-15-34-32(36-20)43-25-12-8-21(9-13-25)28-29(31(33)42)26-17-35-24(19-40)18-39(26)30(28)22-6-10-23(11-7-22)37-27(41)5-4-16-38(2)3/h4-15,17-18,40H,16,19H2,1-3H3,(H2,33,42)(H,37,41)	YPXPZMXURUIHAG-UHFFFAOYSA-N	75526	(E)-6-(4-(4-(dimethylamino) but-2-enamido)phenyl)-3-(hydroxymethyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::(E)-6-(4-(4-(dimethylamino)but-2-enamido)phenyl)-3-(hydroxymethyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 79	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75526	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75526&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1106143	252652733							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120681	Cc1ccnc(Oc2ccc(-c3c(C(N)=O)c4cnc(CO)cn4c3-c3ccc(NC(=O)/C=C/CN(C)C)cc3)cc2)n1	InChI=1S/C32H31N7O4/c1-20-14-15-34-32(36-20)43-25-12-8-21(9-13-25)28-29(31(33)42)26-17-35-24(19-40)18-39(26)30(28)22-6-10-23(11-7-22)37-27(41)5-4-16-38(2)3/h4-15,17-18,40H,16,19H2,1-3H3,(H2,33,42)(H,37,41)	YPXPZMXURUIHAG-UHFFFAOYSA-N	75526	(E)-6-(4-(4-(dimethylamino) but-2-enamido)phenyl)-3-(hydroxymethyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::(E)-6-(4-(4-(dimethylamino)but-2-enamido)phenyl)-3-(hydroxymethyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 79	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75526	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75526&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1106143	252652733							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120682	Cc1ccnc(Oc2ccc(-c3c(C(N)=O)c4cnc(CO)cn4c3-c3ccc(NC(=O)/C=C/CN(C)C)cc3)cc2)n1	InChI=1S/C32H31N7O4/c1-20-14-15-34-32(36-20)43-25-12-8-21(9-13-25)28-29(31(33)42)26-17-35-24(19-40)18-39(26)30(28)22-6-10-23(11-7-22)37-27(41)5-4-16-38(2)3/h4-15,17-18,40H,16,19H2,1-3H3,(H2,33,42)(H,37,41)	YPXPZMXURUIHAG-UHFFFAOYSA-N	75526	(E)-6-(4-(4-(dimethylamino) but-2-enamido)phenyl)-3-(hydroxymethyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::(E)-6-(4-(4-(dimethylamino)but-2-enamido)phenyl)-3-(hydroxymethyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 79	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75526	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75526&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1106143	252652733							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120683	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(CCO)cn23)cc1	InChI=1S/C30H25FN6O4/c1-17-11-13-33-30(35-17)41-23-9-5-19(6-10-23)25-26(28(32)39)24-15-34-22(12-14-38)16-37(24)27(25)20-3-7-21(8-4-20)36-29(40)18(2)31/h3-11,13,15-16,38H,2,12,14H2,1H3,(H2,32,39)(H,36,40)	SDDMQAYLGLAKFZ-UHFFFAOYSA-N	75527	6-(4-(2-fluoroacrylamido)phenyl)-3-(2-hydroxyethyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 80	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75527	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75527&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			24747801	252652734							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120684	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(CCO)cn23)cc1	InChI=1S/C30H25FN6O4/c1-17-11-13-33-30(35-17)41-23-9-5-19(6-10-23)25-26(28(32)39)24-15-34-22(12-14-38)16-37(24)27(25)20-3-7-21(8-4-20)36-29(40)18(2)31/h3-11,13,15-16,38H,2,12,14H2,1H3,(H2,32,39)(H,36,40)	SDDMQAYLGLAKFZ-UHFFFAOYSA-N	75527	6-(4-(2-fluoroacrylamido)phenyl)-3-(2-hydroxyethyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 80	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75527	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75527&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			24747801	252652734							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120685	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(CCO)cn23)cc1	InChI=1S/C30H25FN6O4/c1-17-11-13-33-30(35-17)41-23-9-5-19(6-10-23)25-26(28(32)39)24-15-34-22(12-14-38)16-37(24)27(25)20-3-7-21(8-4-20)36-29(40)18(2)31/h3-11,13,15-16,38H,2,12,14H2,1H3,(H2,32,39)(H,36,40)	SDDMQAYLGLAKFZ-UHFFFAOYSA-N	75527	6-(4-(2-fluoroacrylamido)phenyl)-3-(2-hydroxyethyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 80	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75527	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75527&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			24747801	252652734							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120686	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(CCO)cn23)c(F)c1	InChI=1S/C30H24F2N6O4/c1-16-9-11-34-30(36-16)42-21-6-3-18(4-7-21)25-26(28(33)40)24-14-35-20(10-12-39)15-38(24)27(25)22-8-5-19(13-23(22)32)37-29(41)17(2)31/h3-9,11,13-15,39H,2,10,12H2,1H3,(H2,33,40)(H,37,41)	BWWAFXSQWIOGKR-UHFFFAOYSA-N	75528	6-(2-fluoro-4-(2-fluoroacrylamido)phenyl)-3-(2-hydroxyethyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 81	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75528	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75528&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			947023	252652735							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120687	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(CCO)cn23)c(F)c1	InChI=1S/C30H24F2N6O4/c1-16-9-11-34-30(36-16)42-21-6-3-18(4-7-21)25-26(28(33)40)24-14-35-20(10-12-39)15-38(24)27(25)22-8-5-19(13-23(22)32)37-29(41)17(2)31/h3-9,11,13-15,39H,2,10,12H2,1H3,(H2,33,40)(H,37,41)	BWWAFXSQWIOGKR-UHFFFAOYSA-N	75528	6-(2-fluoro-4-(2-fluoroacrylamido)phenyl)-3-(2-hydroxyethyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 81	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75528	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75528&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			947023	252652735							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120688	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(CCO)cn23)c(F)c1	InChI=1S/C30H24F2N6O4/c1-16-9-11-34-30(36-16)42-21-6-3-18(4-7-21)25-26(28(33)40)24-14-35-20(10-12-39)15-38(24)27(25)22-8-5-19(13-23(22)32)37-29(41)17(2)31/h3-9,11,13-15,39H,2,10,12H2,1H3,(H2,33,40)(H,37,41)	BWWAFXSQWIOGKR-UHFFFAOYSA-N	75528	6-(2-fluoro-4-(2-fluoroacrylamido)phenyl)-3-(2-hydroxyethyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 81	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75528	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75528&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			947023	252652735							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120689	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(CCO)cn23)c(F)c1	InChI=1S/C30H23F3N6O4/c1-15-7-9-35-30(37-15)43-24-6-3-17(11-22(24)33)25-26(28(34)41)23-13-36-19(8-10-40)14-39(23)27(25)20-5-4-18(12-21(20)32)38-29(42)16(2)31/h3-7,9,11-14,40H,2,8,10H2,1H3,(H2,34,41)(H,38,42)	QGPSCZONYIYCIG-UHFFFAOYSA-N	75529	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(2-fluoro-4-(2-fluoroacrylamido)phenyl)-3-(2-hydroxyethyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 82	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75529	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75529&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			5297393	252652736							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120690	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(CCO)cn23)c(F)c1	InChI=1S/C30H23F3N6O4/c1-15-7-9-35-30(37-15)43-24-6-3-17(11-22(24)33)25-26(28(34)41)23-13-36-19(8-10-40)14-39(23)27(25)20-5-4-18(12-21(20)32)38-29(42)16(2)31/h3-7,9,11-14,40H,2,8,10H2,1H3,(H2,34,41)(H,38,42)	QGPSCZONYIYCIG-UHFFFAOYSA-N	75529	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(2-fluoro-4-(2-fluoroacrylamido)phenyl)-3-(2-hydroxyethyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 82	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75529	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75529&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			5297393	252652736							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120691	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(CCO)cn23)c(F)c1	InChI=1S/C30H23F3N6O4/c1-15-7-9-35-30(37-15)43-24-6-3-17(11-22(24)33)25-26(28(34)41)23-13-36-19(8-10-40)14-39(23)27(25)20-5-4-18(12-21(20)32)38-29(42)16(2)31/h3-7,9,11-14,40H,2,8,10H2,1H3,(H2,34,41)(H,38,42)	QGPSCZONYIYCIG-UHFFFAOYSA-N	75529	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(2-fluoro-4-(2-fluoroacrylamido)phenyl)-3-(2-hydroxyethyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 82	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75529	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75529&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			5297393	252652736							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120692	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(NC(C)=O)cn23)cc1	InChI=1S/C30H24FN7O4/c1-16-12-13-33-30(35-16)42-22-10-6-19(7-11-22)25-26(28(32)40)23-14-34-24(36-18(3)39)15-38(23)27(25)20-4-8-21(9-5-20)37-29(41)17(2)31/h4-15H,2H2,1,3H3,(H2,32,40)(H,36,39)(H,37,41)	YDGWLSNAJDNKLY-UHFFFAOYSA-N	75530	3-acetamido-6-(4-(2-fluoroacrylamido)phenyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 83	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75530	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75530&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			20899656	252652737							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120693	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(NC(C)=O)cn23)cc1	InChI=1S/C30H24FN7O4/c1-16-12-13-33-30(35-16)42-22-10-6-19(7-11-22)25-26(28(32)40)23-14-34-24(36-18(3)39)15-38(23)27(25)20-4-8-21(9-5-20)37-29(41)17(2)31/h4-15H,2H2,1,3H3,(H2,32,40)(H,36,39)(H,37,41)	YDGWLSNAJDNKLY-UHFFFAOYSA-N	75530	3-acetamido-6-(4-(2-fluoroacrylamido)phenyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 83	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75530	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75530&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			20899656	252652737							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120694	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)cc3)c(C(N)=O)c3cnc(NC(C)=O)cn23)cc1	InChI=1S/C30H24FN7O4/c1-16-12-13-33-30(35-16)42-22-10-6-19(7-11-22)25-26(28(32)40)23-14-34-24(36-18(3)39)15-38(23)27(25)20-4-8-21(9-5-20)37-29(41)17(2)31/h4-15H,2H2,1,3H3,(H2,32,40)(H,36,39)(H,37,41)	YDGWLSNAJDNKLY-UHFFFAOYSA-N	75530	3-acetamido-6-(4-(2-fluoroacrylamido)phenyl)-7-(4-((4-methylpyrimidin-2-yl)oxy)phenyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 83	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75530	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75530&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			20899656	252652737							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120695	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3ccnc(C)n23)cc1	InChI=1S/C30H25N5O3/c1-4-25(36)34-22-12-8-21(9-13-22)29-27(28(30(31)37)24-16-17-32-19(3)35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	OZTGZPSOVWHQJE-UHFFFAOYSA-N	75531	7-(4-acrylamidophenyl)-1-methyl-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 84	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75531	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75531&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			7192959	252652738							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120696	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3ccnc(C)n23)cc1	InChI=1S/C30H25N5O3/c1-4-25(36)34-22-12-8-21(9-13-22)29-27(28(30(31)37)24-16-17-32-19(3)35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	OZTGZPSOVWHQJE-UHFFFAOYSA-N	75531	7-(4-acrylamidophenyl)-1-methyl-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 84	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75531	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75531&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			7192959	252652738							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120697	C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3ccnc(C)n23)cc1	InChI=1S/C30H25N5O3/c1-4-25(36)34-22-12-8-21(9-13-22)29-27(28(30(31)37)24-16-17-32-19(3)35(24)29)20-10-14-23(15-11-20)38-26-7-5-6-18(2)33-26/h4-17H,1H2,2-3H3,(H2,31,37)(H,34,36)	OZTGZPSOVWHQJE-UHFFFAOYSA-N	75531	7-(4-acrylamidophenyl)-1-methyl-6-(4-((6-methylpyridin-2-yl)oxy)phenyl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 84	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75531	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75531&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			7192959	252652738							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120698	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(C)ncn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-10-11-33-29(35-15)40-23-9-6-19(13-21(23)31)24-25(27(32)38)22-12-16(2)34-14-37(22)26(24)18-4-7-20(8-5-18)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	OTHQCBMDKVHBQG-UHFFFAOYSA-N	75532	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)-3-methylpyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 85	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75532	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75532&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			24789707	252652739							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120699	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(C)ncn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-10-11-33-29(35-15)40-23-9-6-19(13-21(23)31)24-25(27(32)38)22-12-16(2)34-14-37(22)26(24)18-4-7-20(8-5-18)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	OTHQCBMDKVHBQG-UHFFFAOYSA-N	75532	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)-3-methylpyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 85	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75532	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75532&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			24789707	252652739							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120700	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(C)ncn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-10-11-33-29(35-15)40-23-9-6-19(13-21(23)31)24-25(27(32)38)22-12-16(2)34-14-37(22)26(24)18-4-7-20(8-5-18)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	OTHQCBMDKVHBQG-UHFFFAOYSA-N	75532	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)-3-methylpyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 85	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75532	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75532&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			24789707	252652739							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120701	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(-c4cnn(C)c4)ncn23)cc1	InChI=1S/C32H24F2N8O3/c1-17-10-11-36-32(39-17)45-26-9-6-20(12-23(26)34)27-28(30(35)43)25-13-24(21-14-38-41(3)15-21)37-16-42(25)29(27)19-4-7-22(8-5-19)40-31(44)18(2)33/h4-16H,2H2,1,3H3,(H2,35,43)(H,40,44)	IAZNMTMWYNLDCL-UHFFFAOYSA-N	75533	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 86	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75533	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75533&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			768082	252652740							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120702	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(-c4cnn(C)c4)ncn23)cc1	InChI=1S/C32H24F2N8O3/c1-17-10-11-36-32(39-17)45-26-9-6-20(12-23(26)34)27-28(30(35)43)25-13-24(21-14-38-41(3)15-21)37-16-42(25)29(27)19-4-7-22(8-5-19)40-31(44)18(2)33/h4-16H,2H2,1,3H3,(H2,35,43)(H,40,44)	IAZNMTMWYNLDCL-UHFFFAOYSA-N	75533	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 86	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75533	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75533&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			768082	252652740							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120703	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(-c4cnn(C)c4)ncn23)cc1	InChI=1S/C32H24F2N8O3/c1-17-10-11-36-32(39-17)45-26-9-6-20(12-23(26)34)27-28(30(35)43)25-13-24(21-14-38-41(3)15-21)37-16-42(25)29(27)19-4-7-22(8-5-19)40-31(44)18(2)33/h4-16H,2H2,1,3H3,(H2,35,43)(H,40,44)	IAZNMTMWYNLDCL-UHFFFAOYSA-N	75533	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 86	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75533	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75533&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			768082	252652740							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120704	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(C)cnn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-12-22-25(27(32)38)24(19-6-9-23(21(31)13-19)40-29-33-11-10-16(2)35-29)26(37(22)34-14-15)18-4-7-20(8-5-18)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	VIZRMHXRFKBYOW-UHFFFAOYSA-N	75534	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)-3-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 87	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75534	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75534&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1257250	252652741							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120705	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(C)cnn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-12-22-25(27(32)38)24(19-6-9-23(21(31)13-19)40-29-33-11-10-16(2)35-29)26(37(22)34-14-15)18-4-7-20(8-5-18)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	VIZRMHXRFKBYOW-UHFFFAOYSA-N	75534	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)-3-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 87	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75534	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75534&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1257250	252652741							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120706	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(C)cnn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-12-22-25(27(32)38)24(19-6-9-23(21(31)13-19)40-29-33-11-10-16(2)35-29)26(37(22)34-14-15)18-4-7-20(8-5-18)36-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,36,39)	VIZRMHXRFKBYOW-UHFFFAOYSA-N	75534	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)-3-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 87	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75534	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75534&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1257250	252652741							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120707	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(-c4cnn(C)c4)ncn23)c(F)c1	InChI=1S/C32H23F3N8O3/c1-16-8-9-37-32(40-16)46-26-7-4-18(10-23(26)35)27-28(30(36)44)25-12-24(19-13-39-42(3)14-19)38-15-43(25)29(27)21-6-5-20(11-22(21)34)41-31(45)17(2)33/h4-15H,2H2,1,3H3,(H2,36,44)(H,41,45)	VYPQHDGDPJZDIP-UHFFFAOYSA-N	75535	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(2-fluoro-4-(2-fluoroacrylamido)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 91	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75535	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75535&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			6471003	252652742							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120708	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(-c4cnn(C)c4)ncn23)c(F)c1	InChI=1S/C32H23F3N8O3/c1-16-8-9-37-32(40-16)46-26-7-4-18(10-23(26)35)27-28(30(36)44)25-12-24(19-13-39-42(3)14-19)38-15-43(25)29(27)21-6-5-20(11-22(21)34)41-31(45)17(2)33/h4-15H,2H2,1,3H3,(H2,36,44)(H,41,45)	VYPQHDGDPJZDIP-UHFFFAOYSA-N	75535	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(2-fluoro-4-(2-fluoroacrylamido)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 91	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75535	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75535&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			6471003	252652742							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120709	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(-c4cnn(C)c4)ncn23)c(F)c1	InChI=1S/C32H23F3N8O3/c1-16-8-9-37-32(40-16)46-26-7-4-18(10-23(26)35)27-28(30(36)44)25-12-24(19-13-39-42(3)14-19)38-15-43(25)29(27)21-6-5-20(11-22(21)34)41-31(45)17(2)33/h4-15H,2H2,1,3H3,(H2,36,44)(H,41,45)	VYPQHDGDPJZDIP-UHFFFAOYSA-N	75535	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(2-fluoro-4-(2-fluoroacrylamido)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 91	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75535	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75535&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			6471003	252652742							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120710	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(-c4cnn(C)c4)ncn23)c(C)c1	InChI=1S/C33H26F2N8O3/c1-17-11-22(41-32(45)19(3)34)6-7-23(17)30-28(20-5-8-27(24(35)12-20)46-33-37-10-9-18(2)40-33)29(31(36)44)26-13-25(38-16-43(26)30)21-14-39-42(4)15-21/h5-16H,3H2,1-2,4H3,(H2,36,44)(H,41,45)	UJPWUBQTAOXRCE-UHFFFAOYSA-N	75536	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)-2-methylphenyl)-3-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 92	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75536	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75536&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			4851243	252652743							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120711	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(-c4cnn(C)c4)ncn23)c(C)c1	InChI=1S/C33H26F2N8O3/c1-17-11-22(41-32(45)19(3)34)6-7-23(17)30-28(20-5-8-27(24(35)12-20)46-33-37-10-9-18(2)40-33)29(31(36)44)26-13-25(38-16-43(26)30)21-14-39-42(4)15-21/h5-16H,3H2,1-2,4H3,(H2,36,44)(H,41,45)	UJPWUBQTAOXRCE-UHFFFAOYSA-N	75536	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)-2-methylphenyl)-3-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 92	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75536	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75536&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			4851243	252652743							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120712	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(-c4cnn(C)c4)ncn23)c(C)c1	InChI=1S/C33H26F2N8O3/c1-17-11-22(41-32(45)19(3)34)6-7-23(17)30-28(20-5-8-27(24(35)12-20)46-33-37-10-9-18(2)40-33)29(31(36)44)26-13-25(38-16-43(26)30)21-14-39-42(4)15-21/h5-16H,3H2,1-2,4H3,(H2,36,44)(H,41,45)	UJPWUBQTAOXRCE-UHFFFAOYSA-N	75536	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)-2-methylphenyl)-3-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 92	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75536	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75536&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			4851243	252652743							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120713	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3ccc(C)nn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-12-13-33-29(34-15)40-23-11-7-19(14-21(23)31)24-25(27(32)38)22-10-4-16(2)36-37(22)26(24)18-5-8-20(9-6-18)35-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,35,39)	BSOVDEJEKAJGKC-UHFFFAOYSA-N	75537	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 93	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75537	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75537&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			3239048	252652744							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120714	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3ccc(C)nn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-12-13-33-29(34-15)40-23-11-7-19(14-21(23)31)24-25(27(32)38)22-10-4-16(2)36-37(22)26(24)18-5-8-20(9-6-18)35-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,35,39)	BSOVDEJEKAJGKC-UHFFFAOYSA-N	75537	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 93	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75537	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75537&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			3239048	252652744							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120715	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3ccc(C)nn23)cc1	InChI=1S/C29H22F2N6O3/c1-15-12-13-33-29(34-15)40-23-11-7-19(14-21(23)31)24-25(27(32)38)22-10-4-16(2)36-37(22)26(24)18-5-8-20(9-6-18)35-28(39)17(3)30/h4-14H,3H2,1-2H3,(H2,32,38)(H,35,39)	BSOVDEJEKAJGKC-UHFFFAOYSA-N	75537	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 93	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75537	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75537&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			3239048	252652744							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120716	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3ccc(C)nn23)c(C)c1	InChI=1S/C30H24F2N6O3/c1-15-13-20(36-29(40)18(4)31)7-8-21(15)27-25(26(28(33)39)23-9-5-17(3)37-38(23)27)19-6-10-24(22(32)14-19)41-30-34-12-11-16(2)35-30/h5-14H,4H2,1-3H3,(H2,33,39)(H,36,40)	UUQXYDIZXNPOPW-UHFFFAOYSA-N	75538	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)-2-methylphenyl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 94	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75538	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75538&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			215028	252652745							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120717	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3ccc(C)nn23)c(C)c1	InChI=1S/C30H24F2N6O3/c1-15-13-20(36-29(40)18(4)31)7-8-21(15)27-25(26(28(33)39)23-9-5-17(3)37-38(23)27)19-6-10-24(22(32)14-19)41-30-34-12-11-16(2)35-30/h5-14H,4H2,1-3H3,(H2,33,39)(H,36,40)	UUQXYDIZXNPOPW-UHFFFAOYSA-N	75538	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)-2-methylphenyl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 94	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75538	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75538&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			215028	252652745							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120718	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3ccc(C)nn23)c(C)c1	InChI=1S/C30H24F2N6O3/c1-15-13-20(36-29(40)18(4)31)7-8-21(15)27-25(26(28(33)39)23-9-5-17(3)37-38(23)27)19-6-10-24(22(32)14-19)41-30-34-12-11-16(2)35-30/h5-14H,4H2,1-3H3,(H2,33,39)(H,36,40)	UUQXYDIZXNPOPW-UHFFFAOYSA-N	75538	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)-2-methylphenyl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 94	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75538	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75538&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			215028	252652745							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120719	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4ccc(C)nn34)ccc21	InChI=1S/C31H24F2N6O3/c1-16-10-12-35-31(36-16)42-25-9-6-20(15-22(25)33)26-27(29(34)40)24-7-4-17(2)37-39(24)28(26)21-5-8-23-19(14-21)11-13-38(23)30(41)18(3)32/h4-10,12,14-15H,3,11,13H2,1-2H3,(H2,34,40)	IFDBGONSCZHRFO-UHFFFAOYSA-N	75539	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(1-(2-fluoroacryloyl) indolin-5-yl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(1-(2-fluoroacryloyl)indolin-5-yl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 95	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75539	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75539&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2865612	252652746							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120720	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4ccc(C)nn34)ccc21	InChI=1S/C31H24F2N6O3/c1-16-10-12-35-31(36-16)42-25-9-6-20(15-22(25)33)26-27(29(34)40)24-7-4-17(2)37-39(24)28(26)21-5-8-23-19(14-21)11-13-38(23)30(41)18(3)32/h4-10,12,14-15H,3,11,13H2,1-2H3,(H2,34,40)	IFDBGONSCZHRFO-UHFFFAOYSA-N	75539	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(1-(2-fluoroacryloyl) indolin-5-yl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(1-(2-fluoroacryloyl)indolin-5-yl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 95	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75539	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75539&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2865612	252652746							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120721	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4ccc(C)nn34)ccc21	InChI=1S/C31H24F2N6O3/c1-16-10-12-35-31(36-16)42-25-9-6-20(15-22(25)33)26-27(29(34)40)24-7-4-17(2)37-39(24)28(26)21-5-8-23-19(14-21)11-13-38(23)30(41)18(3)32/h4-10,12,14-15H,3,11,13H2,1-2H3,(H2,34,40)	IFDBGONSCZHRFO-UHFFFAOYSA-N	75539	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(1-(2-fluoroacryloyl) indolin-5-yl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(1-(2-fluoroacryloyl)indolin-5-yl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 95	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75539	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75539&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2865612	252652746							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120722	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4ccc(C)nn34)c(C)cc21	InChI=1S/C32H26F2N6O3/c1-16-13-25-20(10-12-39(25)31(42)19(4)33)14-22(16)29-27(28(30(35)41)24-7-5-18(3)38-40(24)29)21-6-8-26(23(34)15-21)43-32-36-11-9-17(2)37-32/h5-9,11,13-15H,4,10,12H2,1-3H3,(H2,35,41)	RGEKGXPDEWVHGF-UHFFFAOYSA-N	75540	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(1-(2-fluoroacryloyl)-6-methylindolin-5-yl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 96	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75540	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75540&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			91898143	252652747							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120723	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4ccc(C)nn34)c(C)cc21	InChI=1S/C32H26F2N6O3/c1-16-13-25-20(10-12-39(25)31(42)19(4)33)14-22(16)29-27(28(30(35)41)24-7-5-18(3)38-40(24)29)21-6-8-26(23(34)15-21)43-32-36-11-9-17(2)37-32/h5-9,11,13-15H,4,10,12H2,1-3H3,(H2,35,41)	RGEKGXPDEWVHGF-UHFFFAOYSA-N	75540	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(1-(2-fluoroacryloyl)-6-methylindolin-5-yl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 96	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75540	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75540&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			91898143	252652747							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120724	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4ccc(C)nn34)c(C)cc21	InChI=1S/C32H26F2N6O3/c1-16-13-25-20(10-12-39(25)31(42)19(4)33)14-22(16)29-27(28(30(35)41)24-7-5-18(3)38-40(24)29)21-6-8-26(23(34)15-21)43-32-36-11-9-17(2)37-32/h5-9,11,13-15H,4,10,12H2,1-3H3,(H2,35,41)	RGEKGXPDEWVHGF-UHFFFAOYSA-N	75540	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(1-(2-fluoroacryloyl)-6-methylindolin-5-yl)-2-methylpyrrolo[1,2-b]pyridazine-5-carboxamide::US20250382297, Example 96	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75540	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75540&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			91898143	252652747							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120725	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)c(C)cc21	InChI=1S/C32H26F2N6O3/c1-16-11-24-20(8-10-39(24)31(42)19(4)33)12-22(16)29-27(28(30(35)41)25-14-37-18(3)15-40(25)29)21-5-6-26(23(34)13-21)43-32-36-9-7-17(2)38-32/h5-7,9,11-15H,4,8,10H2,1-3H3,(H2,35,41)	OZHGREHTLWJSOS-UHFFFAOYSA-N	75541	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl)-6-methylindolin-5-yl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 97	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75541	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75541&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2368087	252652748							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120726	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)c(C)cc21	InChI=1S/C32H26F2N6O3/c1-16-11-24-20(8-10-39(24)31(42)19(4)33)12-22(16)29-27(28(30(35)41)25-14-37-18(3)15-40(25)29)21-5-6-26(23(34)13-21)43-32-36-9-7-17(2)38-32/h5-7,9,11-15H,4,8,10H2,1-3H3,(H2,35,41)	OZHGREHTLWJSOS-UHFFFAOYSA-N	75541	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl)-6-methylindolin-5-yl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 97	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75541	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75541&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2368087	252652748							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120727	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)c(C)cc21	InChI=1S/C32H26F2N6O3/c1-16-11-24-20(8-10-39(24)31(42)19(4)33)12-22(16)29-27(28(30(35)41)25-14-37-18(3)15-40(25)29)21-5-6-26(23(34)13-21)43-32-36-9-7-17(2)38-32/h5-7,9,11-15H,4,8,10H2,1-3H3,(H2,35,41)	OZHGREHTLWJSOS-UHFFFAOYSA-N	75541	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl)-6-methylindolin-5-yl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 97	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75541	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75541&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2368087	252652748							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120908	C=C(F)C(=O)N1CCCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)c(F)cc21	InChI=1S/C32H25F3N6O3/c1-16-8-9-37-32(39-16)44-26-7-6-20(12-23(26)35)27-28(30(36)42)25-14-38-17(2)15-41(25)29(27)21-11-19-5-4-10-40(31(43)18(3)33)24(19)13-22(21)34/h6-9,11-15H,3-5,10H2,1-2H3,(H2,36,42)	ARBMMYAFCKFFOB-UHFFFAOYSA-N	75542	6-(7-fluoro-1-(2-fluoroacryloyl)-1,2,3,4-tetrahydroquinolin-6-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 98	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75542	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75542&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2940387	252652749							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120909	C=C(F)C(=O)N1CCCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)c(F)cc21	InChI=1S/C32H25F3N6O3/c1-16-8-9-37-32(39-16)44-26-7-6-20(12-23(26)35)27-28(30(36)42)25-14-38-17(2)15-41(25)29(27)21-11-19-5-4-10-40(31(43)18(3)33)24(19)13-22(21)34/h6-9,11-15H,3-5,10H2,1-2H3,(H2,36,42)	ARBMMYAFCKFFOB-UHFFFAOYSA-N	75542	6-(7-fluoro-1-(2-fluoroacryloyl)-1,2,3,4-tetrahydroquinolin-6-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 98	Fibroblast growth factor receptor 2	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75542	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75542&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2940387	252652749							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120910	C=C(F)C(=O)N1CCCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)c(F)cc21	InChI=1S/C32H25F3N6O3/c1-16-8-9-37-32(39-16)44-26-7-6-20(12-23(26)35)27-28(30(36)42)25-14-38-17(2)15-41(25)29(27)21-11-19-5-4-10-40(31(43)18(3)33)24(19)13-22(21)34/h6-9,11-15H,3-5,10H2,1-2H3,(H2,36,42)	ARBMMYAFCKFFOB-UHFFFAOYSA-N	75542	6-(7-fluoro-1-(2-fluoroacryloyl)-1,2,3,4-tetrahydroquinolin-6-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 98	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75542	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75542&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2940387	252652749							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120911	C=C(F)C(=O)N1CCc2c1ccc(-c1c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn13)c2F	InChI=1S/C31H23F3N6O3/c1-15-8-10-36-31(38-15)43-24-7-4-18(12-21(24)33)25-26(29(35)41)23-13-37-16(2)14-40(23)28(25)20-5-6-22-19(27(20)34)9-11-39(22)30(42)17(3)32/h4-8,10,12-14H,3,9,11H2,1-2H3,(H2,35,41)	PTXXTLCWJZFQJJ-UHFFFAOYSA-N	75543	6-(4-fluoro-1-(2-fluoroacryloyl) indolin-5-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-fluoro-1-(2-fluoroacryloyl)indolin-5-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 99	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75543	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75543&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			3786957	252652750							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120912	C=C(F)C(=O)N1CCc2c1ccc(-c1c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn13)c2F	InChI=1S/C31H23F3N6O3/c1-15-8-10-36-31(38-15)43-24-7-4-18(12-21(24)33)25-26(29(35)41)23-13-37-16(2)14-40(23)28(25)20-5-6-22-19(27(20)34)9-11-39(22)30(42)17(3)32/h4-8,10,12-14H,3,9,11H2,1-2H3,(H2,35,41)	PTXXTLCWJZFQJJ-UHFFFAOYSA-N	75543	6-(4-fluoro-1-(2-fluoroacryloyl) indolin-5-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-fluoro-1-(2-fluoroacryloyl)indolin-5-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 99	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75543	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75543&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			3786957	252652750							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120913	C=C(F)C(=O)N1CCc2c1ccc(-c1c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn13)c2F	InChI=1S/C31H23F3N6O3/c1-15-8-10-36-31(38-15)43-24-7-4-18(12-21(24)33)25-26(29(35)41)23-13-37-16(2)14-40(23)28(25)20-5-6-22-19(27(20)34)9-11-39(22)30(42)17(3)32/h4-8,10,12-14H,3,9,11H2,1-2H3,(H2,35,41)	PTXXTLCWJZFQJJ-UHFFFAOYSA-N	75543	6-(4-fluoro-1-(2-fluoroacryloyl) indolin-5-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(4-fluoro-1-(2-fluoroacryloyl)indolin-5-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 99	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75543	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75543&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			3786957	252652750							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120914	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(CCO)cn34)ccc21	InChI=1S/C32H26F2N6O4/c1-17-7-10-36-32(38-17)44-26-6-4-20(14-23(26)34)27-28(30(35)42)25-15-37-22(9-12-41)16-40(25)29(27)21-3-5-24-19(13-21)8-11-39(24)31(43)18(2)33/h3-7,10,13-16,41H,2,8-9,11-12H2,1H3,(H2,35,42)	CNAUURMEBVZCBD-UHFFFAOYSA-N	75545	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl) indolin-5-yl)-3-(2-hydroxyethyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl)indolin-5-yl)-3-(2-hydroxyethyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 100	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75545	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75545&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2944534	252652752							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120915	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(CCO)cn34)ccc21	InChI=1S/C32H26F2N6O4/c1-17-7-10-36-32(38-17)44-26-6-4-20(14-23(26)34)27-28(30(35)42)25-15-37-22(9-12-41)16-40(25)29(27)21-3-5-24-19(13-21)8-11-39(24)31(43)18(2)33/h3-7,10,13-16,41H,2,8-9,11-12H2,1H3,(H2,35,42)	CNAUURMEBVZCBD-UHFFFAOYSA-N	75545	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl) indolin-5-yl)-3-(2-hydroxyethyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl)indolin-5-yl)-3-(2-hydroxyethyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 100	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75545	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75545&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2944534	252652752							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120916	C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(CCO)cn34)ccc21	InChI=1S/C32H26F2N6O4/c1-17-7-10-36-32(38-17)44-26-6-4-20(14-23(26)34)27-28(30(35)42)25-15-37-22(9-12-41)16-40(25)29(27)21-3-5-24-19(13-21)8-11-39(24)31(43)18(2)33/h3-7,10,13-16,41H,2,8-9,11-12H2,1H3,(H2,35,42)	CNAUURMEBVZCBD-UHFFFAOYSA-N	75545	7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl) indolin-5-yl)-3-(2-hydroxyethyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-6-(1-(2-fluoroacryloyl)indolin-5-yl)-3-(2-hydroxyethyl)pyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 100	Fibroblast growth factor receptor 3	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75545	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75545&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2944534	252652752							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120917	C=CC(=O)N1CC=C(c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)CC1	InChI=1S/C28H25FN6O3/c1-4-23(36)34-11-8-18(9-12-34)26-24(25(27(30)37)21-14-32-17(3)15-35(21)26)19-5-6-22(20(29)13-19)38-28-31-10-7-16(2)33-28/h4-8,10,13-15H,1,9,11-12H2,2-3H3,(H2,30,37)	DYZYOUJDUFLMHI-UHFFFAOYSA-N	75546	6-(1-acryloyl-1,2,3,6-tetrahydropyridin-4-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 101	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75546	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75546&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			1112934	252652753							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120918	C=CC(=O)N1CC=C(c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)CC1	InChI=1S/C28H25FN6O3/c1-4-23(36)34-11-8-18(9-12-34)26-24(25(27(30)37)21-14-32-17(3)15-35(21)26)19-5-6-22(20(29)13-19)38-28-31-10-7-16(2)33-28/h4-8,10,13-15H,1,9,11-12H2,2-3H3,(H2,30,37)	DYZYOUJDUFLMHI-UHFFFAOYSA-N	75546	6-(1-acryloyl-1,2,3,6-tetrahydropyridin-4-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 101	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75546	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75546&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			1112934	252652753							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120919	C=CC(=O)N1CC=C(c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cnc(C)cn23)CC1	InChI=1S/C28H25FN6O3/c1-4-23(36)34-11-8-18(9-12-34)26-24(25(27(30)37)21-14-32-17(3)15-35(21)26)19-5-6-22(20(29)13-19)38-28-31-10-7-16(2)33-28/h4-8,10,13-15H,1,9,11-12H2,2-3H3,(H2,30,37)	DYZYOUJDUFLMHI-UHFFFAOYSA-N	75546	6-(1-acryloyl-1,2,3,6-tetrahydropyridin-4-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 101	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75546	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75546&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			1112934	252652753							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120920	C=C(F)C(=O)N1CC2(CC2)c2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)c(F)cc21	InChI=1S/C33H25F3N6O3/c1-16-6-9-38-32(40-16)45-26-5-4-19(10-23(26)36)27-28(30(37)43)25-13-39-17(2)14-41(25)29(27)20-11-21-24(12-22(20)35)42(31(44)18(3)34)15-33(21)7-8-33/h4-6,9-14H,3,7-8,15H2,1-2H3,(H2,37,43)	HEFQIWRZEWLDCX-UHFFFAOYSA-N	75547	6-(6'-fluoro-1'-(2-fluoroacryloyl)spiro[cyclopropane-1,3'-indolin]-5'-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(6'-fluoro-1'-(2-fluoroacryloyl)spiro[cyclopropane-1,3'-indolin]-5'-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 102	Fibroblast growth factor receptor 1	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75547	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75547&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			2919564	252652754							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120921	C=C(F)C(=O)N1CC2(CC2)c2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)c(F)cc21	InChI=1S/C33H25F3N6O3/c1-16-6-9-38-32(40-16)45-26-5-4-19(10-23(26)36)27-28(30(37)43)25-13-39-17(2)14-41(25)29(27)20-11-21-24(12-22(20)35)42(31(44)18(3)34)15-33(21)7-8-33/h4-6,9-14H,3,7-8,15H2,1-2H3,(H2,37,43)	HEFQIWRZEWLDCX-UHFFFAOYSA-N	75547	6-(6'-fluoro-1'-(2-fluoroacryloyl)spiro[cyclopropane-1,3'-indolin]-5'-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(6'-fluoro-1'-(2-fluoroacryloyl)spiro[cyclopropane-1,3'-indolin]-5'-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 102	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75547	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75547&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			2919564	252652754							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120922	C=C(F)C(=O)N1CC2(CC2)c2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4cnc(C)cn34)c(F)cc21	InChI=1S/C33H25F3N6O3/c1-16-6-9-38-32(40-16)45-26-5-4-19(10-23(26)36)27-28(30(37)43)25-13-39-17(2)14-41(25)29(27)20-11-21-24(12-22(20)35)42(31(44)18(3)34)15-33(21)7-8-33/h4-6,9-14H,3,7-8,15H2,1-2H3,(H2,37,43)	HEFQIWRZEWLDCX-UHFFFAOYSA-N	75547	6-(6'-fluoro-1'-(2-fluoroacryloyl)spiro[cyclopropane-1,3'-indolin]-5'-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::6-(6'-fluoro-1'-(2-fluoroacryloyl)spiro[cyclopropane-1,3'-indolin]-5'-yl)-7-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-methylpyrrolo[1,2-a]pyrazine-8-carboxamide::US20250382297, Example 102	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75547	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75547&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			2919564	252652754							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120923	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(C4CC4)ncn23)cc1	InChI=1S/C31H24F2N6O3/c1-16-11-12-35-31(37-16)42-25-10-7-20(13-22(25)33)26-27(29(34)40)24-14-23(18-3-4-18)36-15-39(24)28(26)19-5-8-21(9-6-19)38-30(41)17(2)32/h5-15,18H,2-4H2,1H3,(H2,34,40)(H,38,41)	ZEMYJBXCDLQHEG-UHFFFAOYSA-N	75550	3-cyclopropyl-6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 105	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75550	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75550&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			24979260	252652757							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120924	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(C4CC4)ncn23)cc1	InChI=1S/C31H24F2N6O3/c1-16-11-12-35-31(37-16)42-25-10-7-20(13-22(25)33)26-27(29(34)40)24-14-23(18-3-4-18)36-15-39(24)28(26)19-5-8-21(9-6-19)38-30(41)17(2)32/h5-15,18H,2-4H2,1H3,(H2,34,40)(H,38,41)	ZEMYJBXCDLQHEG-UHFFFAOYSA-N	75550	3-cyclopropyl-6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 105	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75550	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75550&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			24979260	252652757							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120925	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(C4CC4)ncn23)cc1	InChI=1S/C31H24F2N6O3/c1-16-11-12-35-31(37-16)42-25-10-7-20(13-22(25)33)26-27(29(34)40)24-14-23(18-3-4-18)36-15-39(24)28(26)19-5-8-21(9-6-19)38-30(41)17(2)32/h5-15,18H,2-4H2,1H3,(H2,34,40)(H,38,41)	ZEMYJBXCDLQHEG-UHFFFAOYSA-N	75550	3-cyclopropyl-6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 105	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75550	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75550&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			24979260	252652757							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120926	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(-c4cnn(C5CC5)c4)ncn23)cc1	InChI=1S/C34H26F2N8O3/c1-18-11-12-38-34(41-18)47-28-10-5-21(13-25(28)36)29-30(32(37)45)27-14-26(22-15-40-44(16-22)24-8-9-24)39-17-43(27)31(29)20-3-6-23(7-4-20)42-33(46)19(2)35/h3-7,10-17,24H,2,8-9H2,1H3,(H2,37,45)(H,42,46)	KFTMNCUVNIAGLX-UHFFFAOYSA-N	75551	3-(1-cyclopropyl-1H-pyrazol-4-yl)-6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 106	Fibroblast growth factor receptor 1	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75551	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75551&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			25161471	252652758							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120927	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(-c4cnn(C5CC5)c4)ncn23)cc1	InChI=1S/C34H26F2N8O3/c1-18-11-12-38-34(41-18)47-28-10-5-21(13-25(28)36)29-30(32(37)45)27-14-26(22-15-40-44(16-22)24-8-9-24)39-17-43(27)31(29)20-3-6-23(7-4-20)42-33(46)19(2)35/h3-7,10-17,24H,2,8-9H2,1H3,(H2,37,45)(H,42,46)	KFTMNCUVNIAGLX-UHFFFAOYSA-N	75551	3-(1-cyclopropyl-1H-pyrazol-4-yl)-6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 106	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75551	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75551&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			25161471	252652758							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120928	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(-c4cnn(C5CC5)c4)ncn23)cc1	InChI=1S/C34H26F2N8O3/c1-18-11-12-38-34(41-18)47-28-10-5-21(13-25(28)36)29-30(32(37)45)27-14-26(22-15-40-44(16-22)24-8-9-24)39-17-43(27)31(29)20-3-6-23(7-4-20)42-33(46)19(2)35/h3-7,10-17,24H,2,8-9H2,1H3,(H2,37,45)(H,42,46)	KFTMNCUVNIAGLX-UHFFFAOYSA-N	75551	3-(1-cyclopropyl-1H-pyrazol-4-yl)-6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)pyrrolo[1,2-c]pyrimidine-5-carboxamide::US20250382297, Example 106	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75551	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75551&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			25161471	252652758							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
120929	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3ccccn23)cc1	InChI=1S/C29H21F2N5O3/c1-16-12-13-33-29(34-16)39-23-11-8-19(15-21(23)31)24-25(27(32)37)22-5-3-4-14-36(22)26(24)18-6-9-20(10-7-18)35-28(38)17(2)30/h3-15H,2H2,1H3,(H2,32,37)(H,35,38)	UXBYRCNVUHHAJH-UHFFFAOYSA-N	75552	2-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-(4-(2-fluoroacrylamido)phenyl) indolizine-1-carboxamide::2-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-(4-(2-fluoroacrylamido)phenyl)indolizine-1-carboxamide::US20250382297, Example 107	Fibroblast growth factor receptor 1	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75552	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75552&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			25163852	252652759							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
121127	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3ccccn23)cc1	InChI=1S/C29H21F2N5O3/c1-16-12-13-33-29(34-16)39-23-11-8-19(15-21(23)31)24-25(27(32)37)22-5-3-4-14-36(22)26(24)18-6-9-20(10-7-18)35-28(38)17(2)30/h3-15H,2H2,1H3,(H2,32,37)(H,35,38)	UXBYRCNVUHHAJH-UHFFFAOYSA-N	75552	2-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-(4-(2-fluoroacrylamido)phenyl) indolizine-1-carboxamide::2-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-(4-(2-fluoroacrylamido)phenyl)indolizine-1-carboxamide::US20250382297, Example 107	Fibroblast growth factor receptor 2	Homo sapiens		<10							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75552	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75552&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			25163852	252652759							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
121128	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3ccccn23)cc1	InChI=1S/C29H21F2N5O3/c1-16-12-13-33-29(34-16)39-23-11-8-19(15-21(23)31)24-25(27(32)37)22-5-3-4-14-36(22)26(24)18-6-9-20(10-7-18)35-28(38)17(2)30/h3-15H,2H2,1H3,(H2,32,37)(H,35,38)	UXBYRCNVUHHAJH-UHFFFAOYSA-N	75552	2-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-(4-(2-fluoroacrylamido)phenyl) indolizine-1-carboxamide::2-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-3-(4-(2-fluoroacrylamido)phenyl)indolizine-1-carboxamide::US20250382297, Example 107	Fibroblast growth factor receptor 3	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75552	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75552&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			25163852	252652759							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
121129	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cncnn23)cc1	InChI=1S/C27H19F2N7O3/c1-14-9-10-32-27(34-14)39-21-8-5-17(11-19(21)29)22-23(25(30)37)20-12-31-13-33-36(20)24(22)16-3-6-18(7-4-16)35-26(38)15(2)28/h3-13H,2H2,1H3,(H2,30,37)(H,35,38)	LGLBSWZFGIJIFO-UHFFFAOYSA-N	75553	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)pyrrolo[2,1-f][1,2,4]triazine-5-carboxamide::US20250382297, Example 108	Fibroblast growth factor receptor 1	Homo sapiens		>1000							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75553	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=694&target=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75553&enzyme=Fibroblast+growth+factor+receptor+1&column=ki&startPg=0&Increment=50&submit=Search			42601352	252652760							1	MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR	8JQI,5A46,3GQI,5ZV2,3RHX,3RI1,1OEC,1GJO,9VLM,7OZY,1EVT,5W59	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362	A8K6T9 A8K8V5 C1KBH8 P17049 Q02063 Q02065 Q14306 Q14307 Q53H63 Q59H40 Q5BJG2 Q8N685 Q9UD50 Q9UDF0 Q9UDF1 Q9UDF2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
121130	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cncnn23)cc1	InChI=1S/C27H19F2N7O3/c1-14-9-10-32-27(34-14)39-21-8-5-17(11-19(21)29)22-23(25(30)37)20-12-31-13-33-36(20)24(22)16-3-6-18(7-4-16)35-26(38)15(2)28/h3-13H,2H2,1H3,(H2,30,37)(H,35,38)	LGLBSWZFGIJIFO-UHFFFAOYSA-N	75553	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)pyrrolo[2,1-f][1,2,4]triazine-5-carboxamide::US20250382297, Example 108	Fibroblast growth factor receptor 2	Homo sapiens		 55							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75553	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=856&target=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75553&enzyme=Fibroblast+growth+factor+receptor+2&column=ki&startPg=0&Increment=50&submit=Search			42601352	252652760							1	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT	2PSQ,1OEC,1GJO,8STG,5EG3,6LVL,6LVK,8H75,9U7S,9U7E,9VLM,7OZY,8YKI,1EV2,1E0O,1DJS	Fibroblast growth factor receptor 2	FGFR2_HUMAN	P21802	B4DFC2 E7EVR6 E9PCR0 P18443 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q8IXC7 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
121131	C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cncnn23)cc1	InChI=1S/C27H19F2N7O3/c1-14-9-10-32-27(34-14)39-21-8-5-17(11-19(21)29)22-23(25(30)37)20-12-31-13-33-36(20)24(22)16-3-6-18(7-4-16)35-26(38)15(2)28/h3-13H,2H2,1H3,(H2,30,37)(H,35,38)	LGLBSWZFGIJIFO-UHFFFAOYSA-N	75553	6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-(4-(2-fluoroacrylamido)phenyl)pyrrolo[2,1-f][1,2,4]triazine-5-carboxamide::US20250382297, Example 108	Fibroblast growth factor receptor 3	Homo sapiens		 550							US Patent		10.7270/Q21J9GK8			US20250382297	DING, X; LIU, Y; WANG, Y; WU, J; LIU, J	12/18/2025	4/29/2026	Insilico Medicine IP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75553	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5611&target=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75553&enzyme=Fibroblast+growth+factor+receptor+3&column=ki&startPg=0&Increment=50&submit=Search			42601352	252652760							1	MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT	1RY7,7YSU	Fibroblast growth factor receptor 3	FGFR3_HUMAN	P22607	D3DVP9 D3DVQ0 Q14308 Q16294 Q16608 Q59FL9