BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
122172	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)CCCCNC(=O)c5ccc6c(Cl)c7c(nc6c5)CCCC7)CC4)cnc3c2)CC1	InChI=1S/C41H51ClN8O5/c1-47-20-22-48(23-21-47)17-13-36(51)45-29-10-12-32-34(25-29)44-27-50(40(32)54)26-41(55)14-18-49(19-15-41)37(52)8-4-5-16-43-39(53)28-9-11-31-35(24-28)46-33-7-3-2-6-30(33)38(31)42/h9-12,24-25,27,55H,2-8,13-23,26H2,1H3,(H,43,53)(H,45,51)	KMAZVJXGDZCRRI-UHFFFAOYSA-N	75857	US12503453, Compound Table1.1::US12503453, Compound 1	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75857	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75857&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			2574532	252653052							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122173	CN(C)CCC(=O)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)CCCCNC(=O)c4ccc5c(Cl)c6c(nc5c4)CCCC6)CC3)cnc2c1	InChI=1S/C38H46ClN7O5/c1-44(2)18-14-33(47)42-26-11-13-29-31(22-26)41-24-46(37(29)50)23-38(51)15-19-45(20-16-38)34(48)9-5-6-17-40-36(49)25-10-12-28-32(21-25)43-30-8-4-3-7-27(30)35(28)39/h10-13,21-22,24,51H,3-9,14-20,23H2,1-2H3,(H,40,49)(H,42,47)	DSOLBTCPBFNPKX-UHFFFAOYSA-N	75874	US12503453, Compound Table1.2::US12503453, Compound 2	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75874	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75874&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			45382326	252653067							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122174	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)CCCCNC(=O)c4ccc5c(Cl)c6c(nc5c4)CCCC6)CC3)cnc2c1	InChI=1S/C40H48ClN7O6/c41-37-29-5-1-2-6-32(29)45-34-23-27(8-10-30(34)37)38(51)42-15-4-3-7-36(50)47-17-13-40(53,14-18-47)25-48-26-43-33-24-28(9-11-31(33)39(48)52)44-35(49)12-16-46-19-21-54-22-20-46/h8-11,23-24,26,53H,1-7,12-22,25H2,(H,42,51)(H,44,49)	UZIIDTMXWPVHBK-UHFFFAOYSA-N	75875	US12503453, Compound Table1.3::US12503453, Compound 3	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 550							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75875	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75875&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			45382320	252653068							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122175	O=C(CCn1ccnc1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)CCCCNC(=O)c4ccc5c(Cl)c6c(nc5c4)CCCC6)CC3)cnc2c1	InChI=1S/C39H43ClN8O5/c40-36-28-5-1-2-6-31(28)45-33-21-26(8-10-29(33)36)37(51)42-15-4-3-7-35(50)47-18-13-39(53,14-19-47)23-48-25-43-32-22-27(9-11-30(32)38(48)52)44-34(49)12-17-46-20-16-41-24-46/h8-11,16,20-22,24-25,53H,1-7,12-15,17-19,23H2,(H,42,51)(H,44,49)	CSHFDHKPWUJHLL-UHFFFAOYSA-N	75876	US12503453, Compound Table1.4::US12503453, Compound 4	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75876	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75876&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			45382322	252653069							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122176	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)c5ccc6c(Cl)c7c(nc6c5)CCCC7)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C48H57ClN8O5/c1-54-24-26-55(27-25-54)21-17-43(58)52-36-14-16-39-41(30-36)51-32-57(47(39)61)31-48(62)18-22-56(23-19-48)46(60)35(28-33-8-3-2-4-9-33)10-7-20-50-45(59)34-13-15-38-42(29-34)53-40-12-6-5-11-37(40)44(38)49/h2-4,8-9,13-16,29-30,32,35,62H,5-7,10-12,17-28,31H2,1H3,(H,50,59)(H,52,58)	UYJWYMWIVMCGQZ-UHFFFAOYSA-N	75877	US12503453, Compound Table1.5::US12503453, Compound 5	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		<20							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75877	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75877&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			45382324	252653070							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122177	CN1CCN(CCC(=O)Nc2ccc3c(c2)ncn(CC2(O)CCN(CC2)C(=O)[C@@H](CCCNC(=O)c2ccc4c(Cl)c5CCCCc5nc4c2)Cc2ccccc2)c3=O)CC1 |r|	InChI=1S/C48H57ClN8O5/c1-54-24-26-55(27-25-54)21-17-43(58)52-36-14-16-39-41(30-36)51-32-57(47(39)61)31-48(62)18-22-56(23-19-48)46(60)35(28-33-8-3-2-4-9-33)10-7-20-50-45(59)34-13-15-38-42(29-34)53-40-12-6-5-11-37(40)44(38)49/h2-4,8-9,13-16,29-30,32,35,62H,5-7,10-12,17-28,31H2,1H3,(H,50,59)(H,52,58)	UYJWYMWIVMCGQZ-UHFFFAOYSA-N	581918	WO2023003973, Compound Table2.3::US12503453, Compound Table1.6::US12503453, Compound 6	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		<20							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581918	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581918&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			153002269	475727733							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122178	CN1CCN(CCC(=O)Nc2ccc3c(c2)ncn(CC2(O)CCN(CC2)C(=O)[C@H](CCCNC(=O)c2ccc4c(Cl)c5CCCCc5nc4c2)Cc2ccccc2)c3=O)CC1 |r|	InChI=1S/C48H57ClN8O5/c1-54-24-26-55(27-25-54)21-17-43(58)52-36-14-16-39-41(30-36)51-32-57(47(39)61)31-48(62)18-22-56(23-19-48)46(60)35(28-33-8-3-2-4-9-33)10-7-20-50-45(59)34-13-15-38-42(29-34)53-40-12-6-5-11-37(40)44(38)49/h2-4,8-9,13-16,29-30,32,35,62H,5-7,10-12,17-28,31H2,1H3,(H,50,59)(H,52,58)	UYJWYMWIVMCGQZ-UHFFFAOYSA-N	581919	WO2023003973, Compound Table2.4::US12503453, Compound Table1.7::US12503453, Compound 7	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 550							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581919	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581919&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			153002270	475727734							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122179	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)CNC(=O)c5ccc6c(Cl)c7c(nc6c5)CCCC7)CC4)cnc3c2)CC1	InChI=1S/C38H45ClN8O5/c1-44-16-18-45(19-17-44)13-10-33(48)42-26-7-9-29-31(21-26)41-24-47(37(29)51)23-38(52)11-14-46(15-12-38)34(49)22-40-36(50)25-6-8-28-32(20-25)43-30-5-3-2-4-27(30)35(28)39/h6-9,20-21,24,52H,2-5,10-19,22-23H2,1H3,(H,40,50)(H,42,48)	VDCOXJAPMHQHRP-UHFFFAOYSA-N	75882	US12503453, Compound Table1.8::US12503453, Compound 8	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75882	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75882&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46172940	252653075							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122180	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)CCNC(=O)c5ccc6c(Cl)c7c(nc6c5)CCCC7)CC4)cnc3c2)CC1	InChI=1S/C39H47ClN8O5/c1-45-18-20-46(21-19-45)15-11-34(49)43-27-7-9-30-32(23-27)42-25-48(38(30)52)24-39(53)12-16-47(17-13-39)35(50)10-14-41-37(51)26-6-8-29-33(22-26)44-31-5-3-2-4-28(31)36(29)40/h6-9,22-23,25,53H,2-5,10-21,24H2,1H3,(H,41,51)(H,43,49)	DIEDXAVYYLVRNW-UHFFFAOYSA-N	75885	US12503453, Compound Table1.9::US12503453, Compound 9	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 550							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75885	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75885&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46172925	252653078							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122181	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)CCCNC(=O)c5ccc6c(Cl)c7c(nc6c5)CCCC7)CC4)cnc3c2)CC1	InChI=1S/C40H49ClN8O5/c1-46-19-21-47(22-20-46)16-12-35(50)44-28-9-11-31-33(24-28)43-26-49(39(31)53)25-40(54)13-17-48(18-14-40)36(51)7-4-15-42-38(52)27-8-10-30-34(23-27)45-32-6-3-2-5-29(32)37(30)41/h8-11,23-24,26,54H,2-7,12-22,25H2,1H3,(H,42,52)(H,44,50)	SACRZNGEDRQWLW-UHFFFAOYSA-N	75888	US12503453, Compound Table1.10::US12503453, Compound 10	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75888	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75888&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46172917	252653081							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122182	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)CCCCCNC(=O)c5ccc6nc7c(c(Cl)c6c5)CCCC7)CC4)cnc3c2)CC1	InChI=1S/C42H53ClN8O5/c1-48-21-23-49(24-22-48)18-14-37(52)46-30-11-12-32-36(26-30)45-28-51(41(32)55)27-42(56)15-19-50(20-16-42)38(53)9-3-2-6-17-44-40(54)29-10-13-35-33(25-29)39(43)31-7-4-5-8-34(31)47-35/h10-13,25-26,28,56H,2-9,14-24,27H2,1H3,(H,44,54)(H,46,52)	VZJISODITGTLHR-UHFFFAOYSA-N	75889	US12503453, Compound Table1.11::US12503453, Compound 11	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75889	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75889&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46172932	252653082							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122183	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCNC(=O)c5ccc6c(Cl)c7c(nc6c5)CCCC7)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C47H55ClN8O5/c1-53-23-25-54(26-24-53)20-16-42(57)51-35-12-14-38-40(29-35)50-31-56(46(38)60)30-47(61)17-21-55(22-18-47)45(59)34(27-32-7-3-2-4-8-32)15-19-49-44(58)33-11-13-37-41(28-33)52-39-10-6-5-9-36(39)43(37)48/h2-4,7-8,11-14,28-29,31,34,61H,5-6,9-10,15-27,30H2,1H3,(H,49,58)(H,51,57)	ADMBQQGGXVLJDX-UHFFFAOYSA-N	75892	US12503453, Compound Table1.12::US12503453, Compound 12	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		<20							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75892	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75892&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46172928	252653085							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122358	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)c5ccc6c(c5)CCCN6C(=O)CCl)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C46H57ClN8O6/c1-51-23-25-52(26-24-51)20-15-41(56)50-37-12-13-38-39(29-37)49-32-54(45(38)60)31-46(61)16-21-53(22-17-46)44(59)36(27-33-7-3-2-4-8-33)9-5-18-48-43(58)35-11-14-40-34(28-35)10-6-19-55(40)42(57)30-47/h2-4,7-8,11-14,28-29,32,36,61H,5-6,9-10,15-27,30-31H2,1H3,(H,48,58)(H,50,56)	QNOQZYTWUSKXNE-UHFFFAOYSA-N	75893	US12503453, Compound Table1.13::US12503453, Compound 13	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75893	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75893&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46172933	252653086							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122359	C=CS(=O)(=O)N1CCCc2cc(C(=O)NCCCC(Cc3ccccc3)C(=O)N3CCC(O)(Cn4cnc5cc(NC(=O)CCN6CCN(C)CC6)ccc5c4=O)CC3)ccc21	InChI=1S/C46H58N8O7S/c1-3-62(60,61)54-21-8-12-35-30-36(13-16-41(35)54)43(56)47-20-7-11-37(29-34-9-5-4-6-10-34)44(57)52-23-18-46(59,19-24-52)32-53-33-48-40-31-38(14-15-39(40)45(53)58)49-42(55)17-22-51-27-25-50(2)26-28-51/h3-6,9-10,13-16,30-31,33,37,59H,1,7-8,11-12,17-29,32H2,2H3,(H,47,56)(H,49,55)	CRIPQDPVRPEVIE-UHFFFAOYSA-N	75894	US12503453, Compound Table1.14::US12503453, Compound 14	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75894	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75894&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46172923	252653087							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122360	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)c5cnccc5Cl)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C40H49ClN8O5/c1-46-20-22-47(23-21-46)17-12-36(50)45-31-9-10-32-35(25-31)44-28-49(39(32)53)27-40(54)13-18-48(19-14-40)38(52)30(24-29-6-3-2-4-7-29)8-5-15-43-37(51)33-26-42-16-11-34(33)41/h2-4,6-7,9-11,16,25-26,28,30,54H,5,8,12-15,17-24,27H2,1H3,(H,43,51)(H,45,50)	NRUROGBYNGQGOV-UHFFFAOYSA-N	75895	US12503453, Compound Table1.15::US12503453, Compound 15	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75895	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75895&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46172937	252653088							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122361	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)c5ccc6c(Cl)c7c(nc6c5)CCCCC7)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C49H59ClN8O5/c1-55-25-27-56(28-26-55)22-18-44(59)53-37-15-17-40-42(31-37)52-33-58(48(40)62)32-49(63)19-23-57(24-20-49)47(61)36(29-34-9-4-2-5-10-34)11-8-21-51-46(60)35-14-16-39-43(30-35)54-41-13-7-3-6-12-38(41)45(39)50/h2,4-5,9-10,14-17,30-31,33,36,63H,3,6-8,11-13,18-29,32H2,1H3,(H,51,60)(H,53,59)	DLBZEXIUOSOYGD-UHFFFAOYSA-N	75903	US12503453, Compound Table1.17::US12503453, Compound 17	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		<20							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75903	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75903&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46835785	252653096							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122362	CN6CCN(CCC(=O)Nc5ccc4c(=O)n(CC3(O)CCN(C(=O)C(CCCNC(=O)C1CCN(C#N)C1)Cc2ccccc2)CC3)cnc4c5)CC6	InChI=1S/C40H53N9O5/c1-45-20-22-46(23-21-45)17-12-36(50)44-33-9-10-34-35(25-33)43-29-49(39(34)53)27-40(54)13-18-48(19-14-40)38(52)31(24-30-6-3-2-4-7-30)8-5-15-42-37(51)32-11-16-47(26-32)28-41/h2-4,6-7,9-10,25,29,31-32,54H,5,8,11-24,26-27H2,1H3,(H,42,51)(H,44,50)	PDXOCUBQZAXQTC-UHFFFAOYSA-N	75908	US12503453, Compound Table1.19::US12503453, Compound 19	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75908	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75908&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			91898153	252653101							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122363	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)C5(C#N)CC5)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C39H50N8O5/c1-44-20-22-45(23-21-44)17-11-34(48)43-31-9-10-32-33(25-31)42-28-47(36(32)50)27-39(52)14-18-46(19-15-39)35(49)30(24-29-6-3-2-4-7-29)8-5-16-41-37(51)38(26-40)12-13-38/h2-4,6-7,9-10,25,28,30,52H,5,8,11-24,27H2,1H3,(H,41,51)(H,43,48)	XRFIMQHDSDVUIR-UHFFFAOYSA-N	75913	US12503453, Compound Table1.20::US12503453, Compound 20	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 550							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75913	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75913&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46835814	252653106							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122469	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)c5cc(C(=O)CCl)cn5C)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C42H53ClN8O6/c1-47-19-21-49(22-20-47)16-12-38(53)46-33-10-11-34-35(25-33)45-29-51(41(34)56)28-42(57)13-17-50(18-14-42)40(55)31(23-30-7-4-3-5-8-30)9-6-15-44-39(54)36-24-32(27-48(36)2)37(52)26-43/h3-5,7-8,10-11,24-25,27,29,31,57H,6,9,12-23,26,28H2,1-2H3,(H,44,54)(H,46,53)	ZFDUPGJPTRQGKW-UHFFFAOYSA-N	75914	US12503453, Compound Table1.21::US12503453, Compound 21	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75914	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75914&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46835807	252653107							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122470	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)[C@H](Cc5ccccc5)NC(=O)CCNC(=O)c5ccc6c(Cl)c7c(nc6c5)CCCC7)CC4)cnc3c2)CC1	InChI=1S/C48H56ClN9O6/c1-55-23-25-56(26-24-55)20-16-43(60)52-34-12-14-37-39(29-34)51-31-58(46(37)62)30-48(64)17-21-57(22-18-48)47(63)41(27-32-7-3-2-4-8-32)54-42(59)15-19-50-45(61)33-11-13-36-40(28-33)53-38-10-6-5-9-35(38)44(36)49/h2-4,7-8,11-14,28-29,31,41,64H,5-6,9-10,15-27,30H2,1H3,(H,50,61)(H,52,60)(H,54,59)	YZZOBGCNEKWIQA-UHFFFAOYSA-N	75922	US12503453, Compound Table1.23::US12503453, Compound 23	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		<20							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75922	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75922&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46835797	252653115							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122471	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4CCN(C(=O)C(CCCNC(=O)c5ccc6c(Cl)c7c(nc6c5)CCCC7)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C48H57ClN8O4/c1-54-24-26-55(27-25-54)21-19-44(58)52-37-14-16-40-42(30-37)51-32-57(48(40)61)31-34-17-22-56(23-18-34)47(60)36(28-33-8-3-2-4-9-33)10-7-20-50-46(59)35-13-15-39-43(29-35)53-41-12-6-5-11-38(41)45(39)49/h2-4,8-9,13-16,29-30,32,34,36H,5-7,10-12,17-28,31H2,1H3,(H,50,59)(H,52,58)	ZXRWGZMELYCYMZ-UHFFFAOYSA-N	75924	US12503453, Compound Table1.24::US12503453, Compound 24	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75924	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75924&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46835815	252653117							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122472	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)[C@H](Cc5ccccc5)NC(=O)CN(C)C(=O)c5ccc6c(Cl)c7c(nc6c5)CCCC7)CC4)cnc3c2)CC1	InChI=1S/C48H56ClN9O6/c1-54-22-24-56(25-23-54)19-16-42(59)51-34-13-15-37-39(28-34)50-31-58(46(37)62)30-48(64)17-20-57(21-18-48)47(63)41(26-32-8-4-3-5-9-32)53-43(60)29-55(2)45(61)33-12-14-36-40(27-33)52-38-11-7-6-10-35(38)44(36)49/h3-5,8-9,12-15,27-28,31,41,64H,6-7,10-11,16-26,29-30H2,1-2H3,(H,51,59)(H,53,60)	DVWGUHVLXIDSRB-UHFFFAOYSA-N	75926	US12503453, Compound Table1.25::US12503453, Compound 25	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		<20							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75926	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75926&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46835796	252653119							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122473	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)[C@H](Cc4c[nH]cn4)NC(=O)CNC(=O)c4ccc5c(Cl)c6c(nc5c4)CCCC6)CC3)cnc2c1	InChI=1S/C43H49ClN10O7/c44-39-30-3-1-2-4-33(30)50-35-19-27(5-7-31(35)39)40(57)46-23-38(56)51-36(21-29-22-45-25-47-29)42(59)53-13-10-43(60,11-14-53)24-54-26-48-34-20-28(6-8-32(34)41(54)58)49-37(55)9-12-52-15-17-61-18-16-52/h5-8,19-20,22,25-26,36,60H,1-4,9-18,21,23-24H2,(H,45,47)(H,46,57)(H,49,55)(H,51,56)	CFKXOJVGGYGCNW-UHFFFAOYSA-N	75927	US12503453, Compound Table1.26::US12503453, Compound 26	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		<20							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75927	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75927&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46835800	252653120							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122474	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)[C@H](CC4CCCCC4)NC(=O)CNC(=O)c4ccc5c(Cl)c6c(nc5c4)CCCC6)CC3)cnc2c1	InChI=1S/C46H57ClN8O7/c47-42-33-8-4-5-9-36(33)51-38-25-31(10-12-34(38)42)43(58)48-27-41(57)52-39(24-30-6-2-1-3-7-30)45(60)54-18-15-46(61,16-19-54)28-55-29-49-37-26-32(11-13-35(37)44(55)59)50-40(56)14-17-53-20-22-62-23-21-53/h10-13,25-26,29-30,39,61H,1-9,14-24,27-28H2,(H,48,58)(H,50,56)(H,52,57)	KBMCXUXNUFNBFX-UHFFFAOYSA-N	75929	US12503453, Compound Table1.27::US12503453, Compound 27	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		<20							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75929	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75929&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46846318	252653122							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122475	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)[C@H](Cc4cscn4)NC(=O)CNC(=O)c4ccc5c(Cl)c6c(nc5c4)CCCC6)CC3)cnc2c1	InChI=1S/C43H48ClN9O7S/c44-39-30-3-1-2-4-33(30)49-35-19-27(5-7-31(35)39)40(56)45-22-38(55)50-36(21-29-23-61-26-47-29)42(58)52-13-10-43(59,11-14-52)24-53-25-46-34-20-28(6-8-32(34)41(53)57)48-37(54)9-12-51-15-17-60-18-16-51/h5-8,19-20,23,25-26,36,59H,1-4,9-18,21-22,24H2,(H,45,56)(H,48,54)(H,50,55)	TXOMHNFGZOBEKR-UHFFFAOYSA-N	75930	US12503453, Compound Table1.28::US12503453, Compound 28	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		<20							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75930	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75930&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46846320	252653123							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122476	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)[C@H](Cc4cc(F)cc(F)c4)NC(=O)CNC(=O)c4ccc5c(Cl)c6c(nc5c4)CCCC6)CC3)cnc2c1	InChI=1S/C46H49ClF2N8O7/c47-42-33-3-1-2-4-36(33)53-38-22-29(5-7-34(38)42)43(60)50-25-41(59)54-39(21-28-19-30(48)23-31(49)20-28)45(62)56-13-10-46(63,11-14-56)26-57-27-51-37-24-32(6-8-35(37)44(57)61)52-40(58)9-12-55-15-17-64-18-16-55/h5-8,19-20,22-24,27,39,63H,1-4,9-18,21,25-26H2,(H,50,60)(H,52,58)(H,54,59)	HEHHBSVDYYBYKQ-UHFFFAOYSA-N	75931	US12503453, Compound Table1.29::US12503453, Compound 29	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		<20							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75931	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75931&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46846324	252653124							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122477	O=C(NCCC[C@@H](Cc1ccccc1)C(=O)N1CCC(O)(Cn2cnc3cc(N4CCOCC4)ccc3c2=O)CC1)c1ccc2c(Cl)c3c(nc2c1)CCCC3	InChI=1S/C44H49ClN6O5/c45-40-34-10-4-5-11-37(34)48-39-26-31(12-14-35(39)40)41(52)46-18-6-9-32(25-30-7-2-1-3-8-30)42(53)50-19-16-44(55,17-20-50)28-51-29-47-38-27-33(13-15-36(38)43(51)54)49-21-23-56-24-22-49/h1-3,7-8,12-15,26-27,29,32,55H,4-6,9-11,16-25,28H2,(H,46,52)	HFAMRGLSMDQIRZ-UHFFFAOYSA-N	75932	US12503453, Compound Table1.30::US12503453, Compound 30	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 550							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75932	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75932&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46846326	252653125							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122478	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)[C@@H](CCCNC(=O)c4ccc(/C=C/C(=O)N5CCCCC5)nc4)Cc4ccccc4)CC3)cnc2c1	InChI=1S/C47H58N8O7/c56-42(17-23-52-26-28-62-29-27-52)51-39-13-15-40-41(31-39)50-34-55(46(40)60)33-47(61)18-24-54(25-19-47)45(59)36(30-35-8-3-1-4-9-35)10-7-20-48-44(58)37-11-12-38(49-32-37)14-16-43(57)53-21-5-2-6-22-53/h1,3-4,8-9,11-16,31-32,34,36,61H,2,5-7,10,17-30,33H2,(H,48,58)(H,51,56)	ZLIBWYJTLGPXDI-UHFFFAOYSA-N	75933	US12503453, Compound Table1.31::US12503453, Compound 31	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75933	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75933&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46846316	252653126							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122479	CC(C)NC(=O)/C=C/c1ccc(C(=O)NCCC[C@@H](Cc2ccccc2)C(=O)N2CCC(O)(Cn3cnc4cc(NC(=O)CCN5CCOCC5)ccc4c3=O)CC2)cn1	InChI=1S/C45H56N8O7/c1-32(2)49-40(54)15-13-36-11-10-35(29-47-36)42(56)46-19-6-9-34(27-33-7-4-3-5-8-33)43(57)52-21-17-45(59,18-22-52)30-53-31-48-39-28-37(12-14-38(39)44(53)58)50-41(55)16-20-51-23-25-60-26-24-51/h3-5,7-8,10-15,28-29,31-32,34,59H,6,9,16-27,30H2,1-2H3,(H,46,56)(H,49,54)(H,50,55)	PMCIWHMFYLJCQG-UHFFFAOYSA-N	75934	US12503453, Compound Table1.32::US12503453, Compound 32	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75934	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75934&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46846325	252653127							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122480	CN(C)C(=O)/C=C/c1ccc(C(=O)NCCC[C@@H](Cc2ccccc2)C(=O)N2CCC(O)(Cn3cnc4cc(NC(=O)CCN5CCOCC5)ccc4c3=O)CC2)cn1	InChI=1S/C44H54N8O7/c1-49(2)40(54)15-13-35-11-10-34(29-46-35)41(55)45-19-6-9-33(27-32-7-4-3-5-8-32)42(56)51-21-17-44(58,18-22-51)30-52-31-47-38-28-36(12-14-37(38)43(52)57)48-39(53)16-20-50-23-25-59-26-24-50/h3-5,7-8,10-15,28-29,31,33,58H,6,9,16-27,30H2,1-2H3,(H,45,55)(H,48,53)	RBHKXMUFTUGODE-UHFFFAOYSA-N	75935	US12503453, Compound Table1.33::US12503453, Compound 33	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75935	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75935&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46846323	252653128							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122481	O=C(CCN1CCN(C(=O)c2ccc3c(Cl)c4c(nc3c2)CCCC4)CC1)N1CCC(O)(Cn2cnc3cc(Cl)ccc3c2=O)CC1	InChI=1S/C35H38Cl2N6O4/c36-24-6-8-27-29(20-24)38-22-43(34(27)46)21-35(47)10-13-41(14-11-35)31(44)9-12-40-15-17-42(18-16-40)33(45)23-5-7-26-30(19-23)39-28-4-2-1-3-25(28)32(26)37/h5-8,19-20,22,47H,1-4,9-18,21H2	ULVUWDXWJIDSFB-UHFFFAOYSA-N	75937	US12503453, Compound Table2.1::US12503453, Compound 34	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 550							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75937	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75937&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46846319	252653130							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122482	O=C(CN1CCN(C(=O)c2ccc3c(Cl)c4c(nc3c2)CCCC4)CC1)N1CCC(O)(Cn2cnc3cc(Cl)ccc3c2=O)CC1	InChI=1S/C34H36Cl2N6O4/c35-23-6-8-26-28(18-23)37-21-42(33(26)45)20-34(46)9-11-40(12-10-34)30(43)19-39-13-15-41(16-14-39)32(44)22-5-7-25-29(17-22)38-27-4-2-1-3-24(27)31(25)36/h5-8,17-18,21,46H,1-4,9-16,19-20H2	BHJCWXBYQZZDBW-UHFFFAOYSA-N	75941	US12503453, Compound Table2.2::US12503453, Compound 35	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75941	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75941&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46846333	252653134							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122935	C#CCNCCCC(Cc1ccccc1)C(=O)N1CCC(O)(Cn2cnc3cc(NC(=O)CCN4CCN(C)CC4)ccc3c2=O)CC1	InChI=1S/C37H49N7O4/c1-3-16-38-17-7-10-30(25-29-8-5-4-6-9-29)35(46)43-19-14-37(48,15-20-43)27-44-28-39-33-26-31(11-12-32(33)36(44)47)40-34(45)13-18-42-23-21-41(2)22-24-42/h1,4-6,8-9,11-12,26,28,30,38,48H,7,10,13-25,27H2,2H3,(H,40,45)	CWJSDHWBPQCPRQ-UHFFFAOYSA-N	75942	US12503453, Compound Table2.3::US12503453, Compound 36	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75942	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75942&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46850889	252653135							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122936	C=CS(=O)(=O)NCCCC(Cc1ccccc1)C(=O)N1CCC(O)(Cn2cnc3cc(NC(=O)CCN4CCN(C)CC4)ccc3c2=O)CC1	InChI=1S/C36H49N7O6S/c1-3-50(48,49)38-16-7-10-29(24-28-8-5-4-6-9-28)34(45)42-18-14-36(47,15-19-42)26-43-27-37-32-25-30(11-12-31(32)35(43)46)39-33(44)13-17-41-22-20-40(2)21-23-41/h3-6,8-9,11-12,25,27,29,38,47H,1,7,10,13-24,26H2,2H3,(H,39,44)	IZTYNSBKNHUZGN-UHFFFAOYSA-N	75943	US12503453, Compound Table2.4::US12503453, Compound 37	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75943	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75943&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46850894	252653136							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122937	C=CC(=O)NCCCC(Cc1ccccc1)C(=O)N1CCC(O)(Cn2cnc3cc(NC(=O)CCN4CCN(C)CC4)ccc3c2=O)CC1	InChI=1S/C37H49N7O5/c1-3-33(45)38-16-7-10-29(24-28-8-5-4-6-9-28)35(47)43-18-14-37(49,15-19-43)26-44-27-39-32-25-30(11-12-31(32)36(44)48)40-34(46)13-17-42-22-20-41(2)21-23-42/h3-6,8-9,11-12,25,27,29,49H,1,7,10,13-24,26H2,2H3,(H,38,45)(H,40,46)	WBJUAKGLSPZBEK-UHFFFAOYSA-N	75944	US12503453, Compound Table2.5::US12503453, Compound 38	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		<20							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75944	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75944&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46850890	252653137							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122938	CN7CCN(CCC(=O)Nc6ccc5c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)c2ccc(/C=C/1CCCCC1=O)cc2)Cc3ccccc3)CC4)cnc5c6)CC7	InChI=1S/C48H59N7O6/c1-52-26-28-53(29-27-52)23-19-44(57)51-40-17-18-41-42(32-40)50-34-55(47(41)60)33-48(61)20-24-54(25-21-48)46(59)39(31-35-8-3-2-4-9-35)11-7-22-49-45(58)37-15-13-36(14-16-37)30-38-10-5-6-12-43(38)56/h2-4,8-9,13-18,30,32,34,39,61H,5-7,10-12,19-29,31,33H2,1H3,(H,49,58)(H,51,57)	MHPPTOGXLWYRRW-UHFFFAOYSA-N	75945	US12503453, Compound Table2.6::US12503453, Compound 39	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75945	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75945&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46850887	252653138							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122939	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)c5ccc6cc7c(nc6c5)CCCC7)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C48H58N8O5/c1-53-24-26-54(27-25-53)21-17-44(57)51-39-15-16-40-43(31-39)50-33-56(47(40)60)32-48(61)18-22-55(23-19-48)46(59)38(28-34-8-3-2-4-9-34)11-7-20-49-45(58)37-14-13-36-29-35-10-5-6-12-41(35)52-42(36)30-37/h2-4,8-9,13-16,29-31,33,38,61H,5-7,10-12,17-28,32H2,1H3,(H,49,58)(H,51,57)	JOCPVWHCYBFRQA-UHFFFAOYSA-N	75946	US12503453, Compound Table2.7::US12503453, Compound 40	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 550							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75946	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75946&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46850893	252653139							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122940	CC1NC(=O)NC1CCCCCC(=O)NCCOCCOCCOCCC(=O)N8CCN(CC(=O)Nc7ccc6c(=O)n(CC5(O)CCN(C(=O)CCCCNC(=O)c4ccc3c(Cl)c2CCCCc2nc3c4)CC5)cnc6c7)CC8	InChI=1S/C58H80ClN11O11/c1-40-46(66-57(77)63-40)10-3-2-4-12-50(71)60-22-30-80-32-34-81-33-31-79-29-18-53(74)69-27-25-67(26-28-69)37-51(72)64-42-15-17-45-48(36-42)62-39-70(56(45)76)38-58(78)19-23-68(24-20-58)52(73)13-7-8-21-61-55(75)41-14-16-44-49(35-41)65-47-11-6-5-9-43(47)54(44)59/h14-17,35-36,39-40,46,78H,2-13,18-34,37-38H2,1H3,(H,60,71)(H,61,75)(H,64,72)(H2,63,66,77)	JBPWLXPZDUEMBB-UHFFFAOYSA-N	75948	US12503453, Compound Table2.8::US12503453, Compound 41	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75948	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75948&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46850892	252653141							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122941	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)[C@H](Cc4ccccc4)NC(=O)COc4ccc5c(Cl)c6c(nc5c4)CCCC6)CC3)cnc2c1	InChI=1S/C45H50ClN7O7/c46-42-33-8-4-5-9-36(33)49-38-26-32(11-13-34(38)42)60-27-41(55)50-39(24-30-6-2-1-3-7-30)44(57)52-18-15-45(58,16-19-52)28-53-29-47-37-25-31(10-12-35(37)43(53)56)48-40(54)14-17-51-20-22-59-23-21-51/h1-3,6-7,10-13,25-26,29,39,58H,4-5,8-9,14-24,27-28H2,(H,48,54)(H,50,55)	NISAMSLTWIDWKY-UHFFFAOYSA-N	75949	US12503453, Compound Table3.1::US12503453, Compound 43	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 550							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75949	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75949&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46850886	252653142							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122942	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)[C@H](Cc4ccccc4)NC(=O)COc4cccc5c(Cl)c6c(nc45)CCCC6)CC3)cnc2c1	InChI=1S/C45H50ClN7O7/c46-41-32-9-4-5-11-35(32)50-42-34(41)10-6-12-38(42)60-27-40(55)49-37(25-30-7-2-1-3-8-30)44(57)52-19-16-45(58,17-20-52)28-53-29-47-36-26-31(13-14-33(36)43(53)56)48-39(54)15-18-51-21-23-59-24-22-51/h1-3,6-8,10,12-14,26,29,37,58H,4-5,9,11,15-25,27-28H2,(H,48,54)(H,49,55)	OBGNLZJUIBFFIN-UHFFFAOYSA-N	75950	US12503453, Compound Table3.2::US12503453, Compound 44	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75950	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75950&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			24997711	252653143							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122943	O=C(NCCCC(Cc1ccccc1)C(=O)N1CCC(O)(Cn2cnc3cc(OCCN4CCOCC4)ccc3c2=O)CC1)c1ccc2c(Cl)c3c(nc2c1)CCCC3	InChI=1S/C46H53ClN6O6/c47-42-36-10-4-5-11-39(36)50-41-28-33(12-14-37(41)42)43(54)48-18-6-9-34(27-32-7-2-1-3-8-32)44(55)52-19-16-46(57,17-20-52)30-53-31-49-40-29-35(13-15-38(40)45(53)56)59-26-23-51-21-24-58-25-22-51/h1-3,7-8,12-15,28-29,31,34,57H,4-6,9-11,16-27,30H2,(H,48,54)	GHNFOKLFBDTSKN-UHFFFAOYSA-N	75951	US12503453, Compound Table3.3::US12503453, Compound 45	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75951	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75951&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			46850888	252653144							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122944	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)C(CCCNC(=O)c4ccc5c(Cl)cc(C(F)(F)F)nc5c4)Cc4ccccc4)CC3)cnc2c1	InChI=1S/C44H47ClF3N7O6/c45-35-26-38(44(46,47)48)52-37-24-30(8-10-33(35)37)40(57)49-15-4-7-31(23-29-5-2-1-3-6-29)41(58)54-17-13-43(60,14-18-54)27-55-28-50-36-25-32(9-11-34(36)42(55)59)51-39(56)12-16-53-19-21-61-22-20-53/h1-3,5-6,8-11,24-26,28,31,60H,4,7,12-23,27H2,(H,49,57)(H,51,56)	POZAQEKKYOZXKZ-UHFFFAOYSA-N	75952	US12503453, Compound Table3.4::US12503453, Compound 46	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 550							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75952	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75952&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			45382319	252653145							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122945	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)[C@@H](Cc5ccccc5)NC(=O)CNC(=O)c5ccc6c(Cl)c7c(nc6c5)CCCC7)CC4)cnc3c2)CC1	InChI=1S/C47H54ClN9O6/c1-54-21-23-55(24-22-54)18-15-41(58)51-33-12-14-36-38(27-33)50-30-57(45(36)61)29-47(63)16-19-56(20-17-47)46(62)40(25-31-7-3-2-4-8-31)53-42(59)28-49-44(60)32-11-13-35-39(26-32)52-37-10-6-5-9-34(37)43(35)48/h2-4,7-8,11-14,26-27,30,40,63H,5-6,9-10,15-25,28-29H2,1H3,(H,49,60)(H,51,58)(H,53,59)	SMIIWUAEPBPVKE-UHFFFAOYSA-N	75953	US12503453, Compound Table3.5::US12503453, Compound 47	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75953	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75953&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			45382321	252653146							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
122946	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)[C@@H](Cc5ccccc5)NC(=O)CNC(=O)c5ccc6c(Cl)ccnc6c5)CC4)cnc3c2)CC1	InChI=1S/C43H48ClN9O6/c1-50-19-21-51(22-20-50)16-12-38(54)48-31-8-10-33-36(25-31)47-28-53(41(33)57)27-43(59)13-17-52(18-14-43)42(58)37(23-29-5-3-2-4-6-29)49-39(55)26-46-40(56)30-7-9-32-34(44)11-15-45-35(32)24-30/h2-11,15,24-25,28,37,59H,12-14,16-23,26-27H2,1H3,(H,46,56)(H,48,54)(H,49,55)	RZLVKIVXZCTTFD-UHFFFAOYSA-N	75954	US12503453, Compound Table3.6::US12503453, Compound 48	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75954	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75954&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			45382323	252653147							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123476	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)[C@H](Cc4ccccc4)n4ccnn4)CC3)cnc2c1	InChI=1S/C32H38N8O5/c41-29(8-12-37-16-18-45-19-17-37)35-25-6-7-26-27(21-25)33-23-39(30(26)42)22-32(44)9-13-38(14-10-32)31(43)28(40-15-11-34-36-40)20-24-4-2-1-3-5-24/h1-7,11,15,21,23,28,44H,8-10,12-14,16-20,22H2,(H,35,41)	RVUMZNGCYJMUPL-UHFFFAOYSA-N	77510	US12503453, Compound Table3.7::US12503453, Compound 49	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77510	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77510&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			644951	252654541							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123477	Cc1cc(Cl)c2ccc(C(=O)NCCCC(Cc3ccccc3)C(=O)N3CCC(O)(Cn4cnc5cc(NC(=O)CCN6CCOCC6)ccc5c4=O)CC3)cc2n1	InChI=1S/C44H50ClN7O6/c1-30-24-37(45)35-11-9-32(26-39(35)48-30)41(54)46-16-5-8-33(25-31-6-3-2-4-7-31)42(55)51-18-14-44(57,15-19-51)28-52-29-47-38-27-34(10-12-36(38)43(52)56)49-40(53)13-17-50-20-22-58-23-21-50/h2-4,6-7,9-12,24,26-27,29,33,57H,5,8,13-23,25,28H2,1H3,(H,46,54)(H,49,53)	GEPXVYZSGYVITP-UHFFFAOYSA-N	77511	US12503453, Compound Table3.8::US12503453, Compound 50	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77511	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77511&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			660000	252654542							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123478	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)C(CCCNC(=O)c4ccc5c(O)ccnc5c4)Cc4ccccc4)CC3)cnc2c1	InChI=1S/C43H49N7O7/c51-38-12-17-44-36-26-31(8-10-34(36)38)40(53)45-16-4-7-32(25-30-5-2-1-3-6-30)41(54)49-19-14-43(56,15-20-49)28-50-29-46-37-27-33(9-11-35(37)42(50)55)47-39(52)13-18-48-21-23-57-24-22-48/h1-3,5-6,8-12,17,26-27,29,32,56H,4,7,13-16,18-25,28H2,(H,44,51)(H,45,53)(H,47,52)	BYAHKVRDYAGLPU-UHFFFAOYSA-N	77512	US12503453, Compound Table3.9::US12503453, Compound 51	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77512	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77512&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			1085027	252654543							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123479	C=CC(=O)Nc1ccccc1-c1cn([C@@H](Cc2ccccc2)C(=O)N2CCC(O)(Cn3cnc4cc(NC(=O)CCN5CCOCC5)ccc4c3=O)CC2)nn1	InChI=1S/C41H45N9O6/c1-2-37(51)44-33-11-7-6-10-31(33)35-26-50(46-45-35)36(24-29-8-4-3-5-9-29)40(54)48-18-15-41(55,16-19-48)27-49-28-42-34-25-30(12-13-32(34)39(49)53)43-38(52)14-17-47-20-22-56-23-21-47/h2-13,25-26,28,36,55H,1,14-24,27H2,(H,43,52)(H,44,51)	ZTZNDVFVJPMNEK-UHFFFAOYSA-N	77513	US12503453, Compound Table3.10::US12503453, Compound 52	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77513	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77513&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			3236552	252654544							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123480	C=CC(=O)Nc1cccc(-c2cn([C@@H](Cc3ccccc3)C(=O)N3CCC(O)(Cn4cnc5cc(NC(=O)CCN6CCOCC6)ccc5c4=O)CC3)nn2)c1	InChI=1S/C41H45N9O6/c1-2-37(51)43-31-10-6-9-30(24-31)35-26-50(46-45-35)36(23-29-7-4-3-5-8-29)40(54)48-17-14-41(55,15-18-48)27-49-28-42-34-25-32(11-12-33(34)39(49)53)44-38(52)13-16-47-19-21-56-22-20-47/h2-12,24-26,28,36,55H,1,13-23,27H2,(H,43,51)(H,44,52)	FAWUJDJPOIDLBL-UHFFFAOYSA-N	77514	US12503453, Compound Table3.11::US12503453, Compound 53	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77514&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			2943575	252654545							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123481	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)c5ccc6c(Cl)cc(C7CCCCC7)nc6c5)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C50H61ClN8O5/c1-56-25-27-57(28-26-56)22-18-46(60)54-39-15-17-41-44(31-39)53-34-59(49(41)63)33-50(64)19-23-58(24-20-50)48(62)38(29-35-9-4-2-5-10-35)13-8-21-52-47(61)37-14-16-40-42(51)32-43(55-45(40)30-37)36-11-6-3-7-12-36/h2,4-5,9-10,14-17,30-32,34,36,38,64H,3,6-8,11-13,18-29,33H2,1H3,(H,52,61)(H,54,60)	ZLAFAVBDPDUVQC-UHFFFAOYSA-N	77515	US12503453, Compound Table3.12::US12503453, Compound 54	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77515	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77515&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			1836620	252654546							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123482	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)c5ccc6c(Cl)cc(-c7cscn7)nc6c5)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C47H52ClN9O5S/c1-54-20-22-55(23-21-54)17-13-43(58)52-35-10-12-37-39(26-35)50-30-57(46(37)61)29-47(62)14-18-56(19-15-47)45(60)34(24-32-6-3-2-4-7-32)8-5-16-49-44(59)33-9-11-36-38(48)27-41(53-40(36)25-33)42-28-63-31-51-42/h2-4,6-7,9-12,25-28,30-31,34,62H,5,8,13-24,29H2,1H3,(H,49,59)(H,52,58)	BXUAOEIBSVHURB-UHFFFAOYSA-N	77516	US12503453, Compound Table3.13::US12503453, Compound 55	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77516&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			680874	252654547							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123483	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)c5ccc6c(Cl)cc(-c7ccc(F)cc7)nc6c5)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C50H54ClFN8O5/c1-57-24-26-58(27-25-57)21-17-46(61)55-39-14-16-41-44(30-39)54-33-60(49(41)64)32-50(65)18-22-59(23-19-50)48(63)37(28-34-6-3-2-4-7-34)8-5-20-53-47(62)36-11-15-40-42(51)31-43(56-45(40)29-36)35-9-12-38(52)13-10-35/h2-4,6-7,9-16,29-31,33,37,65H,5,8,17-28,32H2,1H3,(H,53,62)(H,55,61)	DYSHJTLPOZPCAG-UHFFFAOYSA-N	77517	US12503453, Compound Table3.14::US12503453, Compound 56	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77517	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77517&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			685280	252654548							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123484	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)c5ccc6c(Cl)cc(-c7ccccc7)nc6c5)Cc5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C50H55ClN8O5/c1-56-25-27-57(28-26-56)22-18-46(60)54-39-15-17-41-44(31-39)53-34-59(49(41)63)33-50(64)19-23-58(24-20-50)48(62)38(29-35-9-4-2-5-10-35)13-8-21-52-47(61)37-14-16-40-42(51)32-43(55-45(40)30-37)36-11-6-3-7-12-36/h2-7,9-12,14-17,30-32,34,38,64H,8,13,18-29,33H2,1H3,(H,52,61)(H,54,60)	VNYHQBQVKFGCJT-UHFFFAOYSA-N	77518	US12503453, Compound Table3.15::US12503453, Compound 57	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 550							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77518&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			826184	252654549							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123485	CN1CCN(CCC(=O)Nc2ccc3c(=O)n(CC4(O)CCN(C(=O)C(CCCNC(=O)c5ccc6c(Cl)c7c(nc6c5)CCCC7)c5ccccc5)CC4)cnc3c2)CC1	InChI=1S/C47H55ClN8O5/c1-53-24-26-54(27-25-53)21-17-42(57)51-34-14-16-38-40(29-34)50-31-56(46(38)60)30-47(61)18-22-55(23-19-47)45(59)35(32-8-3-2-4-9-32)11-7-20-49-44(58)33-13-15-37-41(28-33)52-39-12-6-5-10-36(39)43(37)48/h2-4,8-9,13-16,28-29,31,35,61H,5-7,10-12,17-27,30H2,1H3,(H,49,58)(H,51,57)	UGAMLWRMOYNNDY-UHFFFAOYSA-N	77519	US12503453, Compound Table3.16::US12503453, Compound 58	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77519	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77519&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			16409855	252654550							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123486	COc1cccc(CC(CCCNC(=O)c2ccc3c(Cl)c4c(nc3c2)CCCC4)C(=O)N2CCC(O)(Cn3cnc4cc(NC(=O)CCN5CCN(C)CC5)ccc4c3=O)CC2)c1	InChI=1S/C49H59ClN8O6/c1-55-23-25-56(26-24-55)20-16-44(59)53-36-13-15-40-42(30-36)52-32-58(48(40)62)31-49(63)17-21-57(22-18-49)47(61)35(27-33-7-5-9-37(28-33)64-2)8-6-19-51-46(60)34-12-14-39-43(29-34)54-41-11-4-3-10-38(41)45(39)50/h5,7,9,12-15,28-30,32,35,63H,3-4,6,8,10-11,16-27,31H2,1-2H3,(H,51,60)(H,53,59)	OHRPPKOFRMTTKL-UHFFFAOYSA-N	77520	US12503453, Compound Table3.17::US12503453, Compound 59	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		>1000							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77520&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			2887361	252654551							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123487	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)C(CCCNC(=O)c4ccc5c(Cl)c6c(nc5c4)CCCC6)Cc4ccc(F)c(C(F)(F)F)c4)CC3)cnc2c1	InChI=1S/C48H52ClF4N7O6/c49-43-34-5-1-2-6-39(34)57-41-26-31(8-10-35(41)43)44(62)54-16-3-4-32(24-30-7-12-38(50)37(25-30)48(51,52)53)45(63)59-18-14-47(65,15-19-59)28-60-29-55-40-27-33(9-11-36(40)46(60)64)56-42(61)13-17-58-20-22-66-23-21-58/h7-12,25-27,29,32,65H,1-6,13-24,28H2,(H,54,62)(H,56,61)	DXAHEDYKWXEPER-UHFFFAOYSA-N	77522	US12503453, Compound Table3.18::US12503453, Compound 60	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77522&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			1487451	252654553							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123488	O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)C(CCCNC(=O)c4ccc5c(Cl)c6c(nc5c4)CCCC6)Cc4ccc(F)cc4F)CC3)cnc2c1	InChI=1S/C47H52ClF2N7O6/c48-43-35-5-1-2-6-39(35)54-41-25-31(8-11-36(41)43)44(59)51-16-3-4-32(24-30-7-9-33(49)26-38(30)50)45(60)56-18-14-47(62,15-19-56)28-57-29-52-40-27-34(10-12-37(40)46(57)61)53-42(58)13-17-55-20-22-63-23-21-55/h7-12,25-27,29,32,62H,1-6,13-24,28H2,(H,51,59)(H,53,58)	TXHWRSALLYXNQG-UHFFFAOYSA-N	77523	US12503453, Compound Table3.19::US12503453, Compound 61	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77523	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77523&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			2828945	252654554							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123489	CN1CCN(c2cccc3c(=O)n(CC4(O)CCN(C(=O)[C@@H](CCCNC(=O)c5ccc6c(Cl)c7c(nc6c5)CCCC7)Cc5ccccc5)CC4)cnc23)CC1	InChI=1S/C45H52ClN7O4/c1-50-23-25-51(26-24-50)39-15-7-13-36-41(39)48-30-53(44(36)56)29-45(57)18-21-52(22-19-45)43(55)33(27-31-9-3-2-4-10-31)11-8-20-47-42(54)32-16-17-35-38(28-32)49-37-14-6-5-12-34(37)40(35)46/h2-4,7,9-10,13,15-17,28,30,33,57H,5-6,8,11-12,14,18-27,29H2,1H3,(H,47,54)	QNIZVGBALWNPEW-UHFFFAOYSA-N	77524	US12503453, Compound Table3.20::US12503453, Compound 62	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77524&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			845583	252654555							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
123490	O=C(NCCC[C@@H](Cc1ccccc1)C(=O)N1CCC(O)(Cn2cnc3c(N4CCOCC4)cccc3c2=O)CC1)c1ccc2c(Cl)c3c(nc2c1)CCCC3	InChI=1S/C44H49ClN6O5/c45-39-33-11-4-5-13-36(33)48-37-27-31(15-16-34(37)39)41(52)46-19-7-10-32(26-30-8-2-1-3-9-30)42(53)50-20-17-44(55,18-21-50)28-51-29-47-40-35(43(51)54)12-6-14-38(40)49-22-24-56-25-23-49/h1-3,6,8-9,12,14-16,27,29,32,55H,4-5,7,10-11,13,17-26,28H2,(H,46,52)	CJEQIDHTYVDRBH-UHFFFAOYSA-N	77525	US12503453, Compound Table3.21::US12503453, Compound 63	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens		 60							US Patent		10.7270/Q2NC6602			US12503453	Buhrlage, S; Liu, X	12/23/2025	5/4/2026	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006155&target=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77525&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+7&column=ki&startPg=0&Increment=50&submit=Search			2984161	252654556							1	MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN	9K2X,9K2W,5FWI,5J7T,7XPY,5C56,4YOC,2YLM,4Z97,4Z96,7VIJ,6P5L,9FIR,9FIQ,9FIP,9FIO,5NGF,5NGE,4M5X,4M5W,9QJE,7CM2,4WPI,4WPH,9SZO,9SZN,9IML,9IJU,5VSK,5VSB,5VS6,1NBF,1NB8,9FIV,9FIU,9FIT,6VN6,6VN5,6VN4,6VN3,6VN2,7XHH,5UQX,5JTJ,5JTV,9DEP,9DEO,9DEN,9DEM,9DEL,9DEK,6M1K,5UQV,5WHC,5GG4,5C6D,4PYZ,2F1W,4KG9,4YSI,2XXN,2KVR	Ubiquitin carboxyl-terminal hydrolase 7	UBP7_HUMAN	Q93009	A6NMY8 B7Z815 H0Y3G8