BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
124093	CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOCCOCCOCCOCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C55H65ClN8O12S/c1-3-77(67,68)62-40-10-15-51(47(33-40)48-37-63(2)55(66)53-46(48)17-20-58-53)76-44-6-4-5-43(34-44)74-32-30-72-28-26-70-24-23-69-25-27-71-29-31-73-41-18-21-64(22-19-41)52-16-14-50(60-61-52)54(65)59-39-8-12-42(13-9-39)75-45-11-7-38(36-57)49(56)35-45/h4-7,10-11,14-17,20,33-35,37,39,41-42,58,62H,3,8-9,12-13,18-19,21-32H2,1-2H3,(H,59,65)	DJSPPYLXDYITKE-UHFFFAOYSA-N	79926	US20250388575, Compound I-3	Androgen receptor	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79926	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79926&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			15990985	252656570							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124094	CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H49ClN8O8S/c1-3-65(59,60)54-32-10-15-43(39(25-32)40-29-55(2)47(58)45-38(40)17-20-50-45)64-36-6-4-5-35(26-36)62-24-23-61-33-18-21-56(22-19-33)44-16-14-42(52-53-44)46(57)51-31-8-12-34(13-9-31)63-37-11-7-30(28-49)41(48)27-37/h4-7,10-11,14-17,20,25-27,29,31,33-34,50,54H,3,8-9,12-13,18-19,21-24H2,1-2H3,(H,51,57)	GSOVRHHVRVFNMZ-UHFFFAOYSA-N	79927	US20250388575, Compound I-1	Androgen receptor	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79927	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79927&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			22429402	252656571							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124095	CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOC3CCN(c4ncc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H49ClN8O8S/c1-3-65(59,60)54-33-10-14-43(40(23-33)41-29-55(2)46(58)44-39(41)15-18-50-44)64-37-6-4-5-36(24-37)62-22-21-61-34-16-19-56(20-17-34)47-51-27-31(28-52-47)45(57)53-32-8-12-35(13-9-32)63-38-11-7-30(26-49)42(48)25-38/h4-7,10-11,14-15,18,23-25,27-29,32,34-35,50,54H,3,8-9,12-13,16-17,19-22H2,1-2H3,(H,53,57)	PZIIMYYCCXRKPP-UHFFFAOYSA-N	79928	US20250388575, Compound I-5	Androgen receptor	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79928	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79928&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			24789905	252656572							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124096	CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H50ClN7O8S/c1-3-65(59,60)54-34-11-15-44(41(25-34)42-30-55(2)48(58)46-40(42)17-20-51-46)64-38-6-4-5-37(26-38)62-24-23-61-35-18-21-56(22-19-35)45-16-8-32(29-52-45)47(57)53-33-9-13-36(14-10-33)63-39-12-7-31(28-50)43(49)27-39/h4-8,11-12,15-17,20,25-27,29-30,33,35-36,51,54H,3,9-10,13-14,18-19,21-24H2,1-2H3,(H,53,57)	JOPJEHSSZJZYQO-UHFFFAOYSA-N	79929	US20250388575, Compound I-7	Androgen receptor	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79929	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79929&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			24031031	252656573							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124097	CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nc4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H50ClN7O8S/c1-3-65(59,60)54-33-10-16-45(41(25-33)42-30-55(2)48(58)46-40(42)17-20-51-46)64-38-6-4-5-37(26-38)62-24-23-61-35-18-21-56(22-19-35)34-11-15-44(52-29-34)47(57)53-32-8-13-36(14-9-32)63-39-12-7-31(28-50)43(49)27-39/h4-7,10-12,15-17,20,25-27,29-30,32,35-36,51,54H,3,8-9,13-14,18-19,21-24H2,1-2H3,(H,53,57)	ORDHLDFAZBUHGT-UHFFFAOYSA-N	79930	US20250388575, Compound I-9	Androgen receptor	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79930	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79930&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			20880646	252656574							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124098	CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cc4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C49H51ClN6O8S/c1-3-65(59,60)54-35-12-18-46(43(27-35)44-31-55(2)49(58)47-42(44)19-22-52-47)64-40-6-4-5-39(28-40)62-26-25-61-37-20-23-56(24-21-37)36-13-7-32(8-14-36)48(57)53-34-10-16-38(17-11-34)63-41-15-9-33(30-51)45(50)29-41/h4-9,12-15,18-19,22,27-29,31,34,37-38,52,54H,3,10-11,16-17,20-21,23-26H2,1-2H3,(H,53,57)	LTQOXJXTJBUHGL-UHFFFAOYSA-N	79931	US20250388575, Compound I-6	Androgen receptor	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79931	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79931&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			3228462	252656575							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124099	CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOC3CCN(c4cnc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H49ClN8O8S/c1-3-65(59,60)54-32-10-14-43(39(23-32)40-29-55(2)47(58)45-38(40)15-18-50-45)64-36-6-4-5-35(24-36)62-22-21-61-33-16-19-56(20-17-33)44-28-51-42(27-52-44)46(57)53-31-8-12-34(13-9-31)63-37-11-7-30(26-49)41(48)25-37/h4-7,10-11,14-15,18,23-25,27-29,31,33-34,50,54H,3,8-9,12-13,16-17,19-22H2,1-2H3,(H,53,57)	OPAZBTFBDOVHCE-UHFFFAOYSA-N	79932	US20250388575, Compound I-8	Androgen receptor	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79932	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79932&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			16007609	252656576							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124100	CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOC3CCN(c4cnc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nc4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H49ClN8O8S/c1-3-65(59,60)54-32-10-14-43(40(23-32)41-29-55(2)47(58)44-39(41)15-18-50-44)64-37-6-4-5-36(24-37)62-22-21-61-34-16-19-56(20-17-34)33-27-51-45(52-28-33)46(57)53-31-8-12-35(13-9-31)63-38-11-7-30(26-49)42(48)25-38/h4-7,10-11,14-15,18,23-25,27-29,31,34-35,50,54H,3,8-9,12-13,16-17,19-22H2,1-2H3,(H,53,57)	XGHFZLMRDJSUCU-UHFFFAOYSA-N	79933	US20250388575, Compound I-10	Androgen receptor	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79933	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79933&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			24793385	252656577							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124101	CCS(=O)(=O)Cc1ccc(Oc2cccc(OCCOC3CCN(c4cnc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H49ClFN7O8S/c1-3-66(60,61)29-30-7-14-41(37(23-30)38-28-56(2)48(59)46-36(38)15-18-52-46)65-43-6-4-5-42(45(43)50)63-22-21-62-33-16-19-57(20-17-33)44-27-53-40(26-54-44)47(58)55-32-9-12-34(13-10-32)64-35-11-8-31(25-51)39(49)24-35/h4-8,11,14-15,18,23-24,26-28,32-34,52H,3,9-10,12-13,16-17,19-22,29H2,1-2H3,(H,55,58)	YWPUKGUBHRACON-UHFFFAOYSA-N	79934	US20250388575, Compound I-28	Androgen receptor	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79934	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79934&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			1104012	252656578							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124102	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c2cc[nH]c2c1=O	InChI=1S/C48H50ClN7O5/c1-48(2,59)33-9-18-43(39(26-33)40-29-55(3)47(58)45-38(40)20-23-51-45)61-36-12-6-30(7-13-36)4-5-31-21-24-56(25-22-31)44-19-17-42(53-54-44)46(57)52-34-10-15-35(16-11-34)60-37-14-8-32(28-50)41(49)27-37/h6-9,12-14,17-20,23,26-27,29,31,34-35,51,59H,4-5,10-11,15-16,21-22,24-25H2,1-3H3,(H,52,57)	FVVPXQWBCYXCAL-UHFFFAOYSA-N	79935	US20250388575, Compound I-102	Androgen receptor	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79935	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79935&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			24816908	252656579							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124103	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2ccc(C3CN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)C3)cc2)c2cc[nH]c2c1=O	InChI=1S/C44H42ClN7O5/c1-44(2,55)29-7-16-39(35(20-29)36-25-51(3)43(54)41-34(36)18-19-47-41)57-32-10-4-26(5-11-32)28-23-52(24-28)40-17-15-38(49-50-40)42(53)48-30-8-13-31(14-9-30)56-33-12-6-27(22-46)37(45)21-33/h4-7,10-12,15-21,25,28,30-31,47,55H,8-9,13-14,23-24H2,1-3H3,(H,48,53)	DBNBAIFVOZINFN-UHFFFAOYSA-N	79936	US20250388575, Compound I-104	Androgen receptor	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79936	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79936&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			91898289	252656580							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124104	CCS(=O)(=O)Cc1ccc(Oc2cccc(CCCCC3CCN(c4ncc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C50H54ClN7O6S/c1-3-65(61,62)32-35-11-18-46(43(26-35)44-31-57(2)49(60)47-42(44)19-22-53-47)64-40-10-6-9-34(25-40)8-5-4-7-33-20-23-58(24-21-33)50-54-29-37(30-55-50)48(59)56-38-13-16-39(17-14-38)63-41-15-12-36(28-52)45(51)27-41/h6,9-12,15,18-19,22,25-27,29-31,33,38-39,53H,3-5,7-8,13-14,16-17,20-21,23-24,32H2,1-2H3,(H,56,59)	ZLZVMUYNIGEFMP-UHFFFAOYSA-N	79937	US20250388575, Compound I-158	Androgen receptor	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79937	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79937&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			24817165	252656581							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124105	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2ccc(CCC3CCN(c4cnc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)cc2)c2cc[nH]c2c1=O	InChI=1S/C48H50ClN7O5/c1-48(2,59)33-9-17-43(39(24-33)40-29-55(3)47(58)45-38(40)18-21-51-45)61-36-12-6-30(7-13-36)4-5-31-19-22-56(23-20-31)44-28-52-42(27-53-44)46(57)54-34-10-15-35(16-11-34)60-37-14-8-32(26-50)41(49)25-37/h6-9,12-14,17-18,21,24-25,27-29,31,34-35,51,59H,4-5,10-11,15-16,19-20,22-23H2,1-3H3,(H,54,57)	LIPARGDONUXDIS-UHFFFAOYSA-N	79938	US20250388575, Compound I-119	Androgen receptor	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79938	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1924&target=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79938&enzyme=Androgen+receptor&column=ki&startPg=0&Increment=50&submit=Search			3286670	252656582							1	MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ	5CJ6,3V49,2PNU,2AMB,2AMA,2AM9,1E3G,4QL8,2Q7J,2Q7I,1XJ7,4HLW,3ZQT,3G0W,2YLQ,2YLP,2YLO,2NW4,2IHQ,2AXA,2AX9,1I37,5JJM,1T7T,1T7R,1T7M,1T7F,1T79,1T76,1T74,1T73,2QPY,2PKL,2PIX,2PIW,2PIV,2PIU,2PIT,2PIR,2PIQ,2PIP,2PIO,1T65,1T63,1T5Z,2HVC,5VO4,9GZD,3V4A,3L3Z,3L3X,3B68,3B67,3B66,3B65,3B5R,2YHD,2AO6,1XQ3,1XOW,2Z4J,3RLJ	Androgen receptor	ANDR_HUMAN	P10275	A0A0B4J1T2 A2RUN2 B1AKD7 C0JKD3 C0JKD4 E7EVX6 Q9UD95																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124106	CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOCCOCCOCCOCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C55H65ClN8O12S/c1-3-77(67,68)62-40-10-15-51(47(33-40)48-37-63(2)55(66)53-46(48)17-20-58-53)76-44-6-4-5-43(34-44)74-32-30-72-28-26-70-24-23-69-25-27-71-29-31-73-41-18-21-64(22-19-41)52-16-14-50(60-61-52)54(65)59-39-8-12-42(13-9-39)75-45-11-7-38(36-57)49(56)35-45/h4-7,10-11,14-17,20,33-35,37,39,41-42,58,62H,3,8-9,12-13,18-19,21-32H2,1-2H3,(H,59,65)	DJSPPYLXDYITKE-UHFFFAOYSA-N	79926	US20250388575, Compound I-3	Bromodomain-containing protein 4 [58-164]	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79926	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79926&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			15990985	252656570							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124107	CCS(=O)(=O)Nc1ccc(Oc2ccc(OCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C46H47ClN8O7S/c1-3-63(58,59)53-32-7-16-42(38(24-32)39-27-54(2)46(57)44-37(39)18-21-49-44)62-35-13-11-33(12-14-35)60-28-29-19-22-55(23-20-29)43-17-15-41(51-52-43)45(56)50-31-5-9-34(10-6-31)61-36-8-4-30(26-48)40(47)25-36/h4,7-8,11-18,21,24-25,27,29,31,34,49,53H,3,5-6,9-10,19-20,22-23,28H2,1-2H3,(H,50,56)	QNPJMLJOWSSDTA-UHFFFAOYSA-N	79939	US20250388575, Compound I-33	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79939	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79939&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			1950409	252656583							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124108	CCS(=O)(=O)c1ccc(Oc2cccc(OCCCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H49ClFN7O7S/c1-3-65(60,61)35-15-17-41(37(27-35)38-29-56(2)48(59)46-36(38)19-22-52-46)64-43-8-4-7-42(45(43)50)62-25-5-6-30-20-23-57(24-21-30)44-18-16-40(54-55-44)47(58)53-32-10-13-33(14-11-32)63-34-12-9-31(28-51)39(49)26-34/h4,7-9,12,15-19,22,26-27,29-30,32-33,52H,3,5-6,10-11,13-14,20-21,23-25H2,1-2H3,(H,53,58)	BSBAKUWVVBPLLJ-UHFFFAOYSA-N	79940	US20250388575, Compound I-15	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79940	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79940&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			24818804	252656584							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124109	CCS(=O)(=O)Nc1ccc(Oc2ccc(CCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H49ClN8O7S/c1-3-64(59,60)54-33-9-16-43(39(26-33)40-29-55(2)47(58)45-38(40)18-22-50-45)63-36-10-4-30(5-11-36)21-25-61-34-19-23-56(24-20-34)44-17-15-42(52-53-44)46(57)51-32-7-13-35(14-8-32)62-37-12-6-31(28-49)41(48)27-37/h4-6,9-12,15-18,22,26-27,29,32,34-35,50,54H,3,7-8,13-14,19-21,23-25H2,1-2H3,(H,51,57)	HZFCHSMDVKJBNT-UHFFFAOYSA-N	79941	US20250388575, Compound I-35	Bromodomain-containing protein 4 [58-164]	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79941	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79941&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			24819158	252656585							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124110	CCS(=O)(=O)Nc1ccc(Oc2ccc(CCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H51ClN8O7S/c1-3-65(60,61)55-34-11-18-44(40(27-34)41-30-56(2)48(59)46-39(41)20-23-51-46)64-37-12-6-31(7-13-37)5-4-26-62-35-21-24-57(25-22-35)45-19-17-43(53-54-45)47(58)52-33-9-15-36(16-10-33)63-38-14-8-32(29-50)42(49)28-38/h6-8,11-14,17-20,23,27-28,30,33,35-36,51,55H,3-5,9-10,15-16,21-22,24-26H2,1-2H3,(H,52,58)	CRQIIMVPBBDNQB-UHFFFAOYSA-N	79942	US20250388575, Compound I-36	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79942	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79942&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			24819406	252656586							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124111	CCS(=O)(=O)Cc1ccc(Oc2cccc(OCCCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C49H51ClFN7O7S/c1-3-66(61,62)30-32-9-17-42(38(26-32)39-29-57(2)49(60)47-37(39)19-22-53-47)65-44-8-4-7-43(46(44)51)63-25-5-6-31-20-23-58(24-21-31)45-18-16-41(55-56-45)48(59)54-34-11-14-35(15-12-34)64-36-13-10-33(28-52)40(50)27-36/h4,7-10,13,16-19,22,26-27,29,31,34-35,53H,3,5-6,11-12,14-15,20-21,23-25,30H2,1-2H3,(H,54,59)	PDGPUENKHMYNCK-UHFFFAOYSA-N	79943	US20250388575, Compound I-20	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79943	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79943&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			16830239	252656587							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124112	CCS(=O)(=O)Cc1ccc(Oc2cccc(CCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C49H51ClFN7O7S/c1-3-66(61,62)30-31-9-17-43(39(26-31)40-29-57(2)49(60)47-38(40)19-22-53-47)65-44-8-4-6-32(46(44)51)7-5-25-63-35-20-23-58(24-21-35)45-18-16-42(55-56-45)48(59)54-34-11-14-36(15-12-34)64-37-13-10-33(28-52)41(50)27-37/h4,6,8-10,13,16-19,22,26-27,29,34-36,53H,3,5,7,11-12,14-15,20-21,23-25,30H2,1-2H3,(H,54,59)	IHHJMQNFPRLCDB-UHFFFAOYSA-N	79944	US20250388575, Compound I-29	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79944	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79944&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			24979400	252656588							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124113	CCS(=O)(=O)Nc1ccc(OCC(OCCOC2CCN(c3ccc(C(=O)N[C@H]4CC[C@H](Oc5ccc(C#N)c(Cl)c5)CC4)nn3)CC2)C2CC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C46H53ClN8O8S/c1-3-64(58,59)53-32-9-14-41(37(24-32)38-27-54(2)46(57)44-36(38)16-19-49-44)62-28-42(29-4-5-29)61-23-22-60-33-17-20-55(21-18-33)43-15-13-40(51-52-43)45(56)50-31-7-11-34(12-8-31)63-35-10-6-30(26-48)39(47)25-35/h6,9-10,13-16,19,24-25,27,29,31,33-34,42,49,53H,3-5,7-8,11-12,17-18,20-23,28H2,1-2H3,(H,50,56)	VHBRMSLGESEWMS-UHFFFAOYSA-N	79945	US20250388575, Compound I-30	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79945	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79945&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			24979750	252656589							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124114	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2ccc(OC3CN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)C3)cc2)c2cc[nH]c2c1=O	InChI=1S/C44H42ClN7O6/c1-44(2,55)27-5-16-39(35(20-27)36-25-51(3)43(54)41-34(36)18-19-47-41)58-31-13-11-30(12-14-31)57-33-23-52(24-33)40-17-15-38(49-50-40)42(53)48-28-6-9-29(10-7-28)56-32-8-4-26(22-46)37(45)21-32/h4-5,8,11-21,25,28-29,33,47,55H,6-7,9-10,23-24H2,1-3H3,(H,48,53)	YERIFSQXBJEXQC-UHFFFAOYSA-N	79946	US20250388575, Compound I-95	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79946	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79946&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			24982063	252656590							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124115	CN(c1ccc(Oc2ccc(C(C)(C)O)cc2-c2cn(C)c(=O)c3[nH]ccc23)cc1)C1CCN(c2ccc(C(=O)N[C@H]3CC[C@H](Oc4ccc(C#N)c(Cl)c4)CC3)nn2)CC1	InChI=1S/C47H49ClN8O5/c1-47(2,59)30-6-17-42(38(25-30)39-28-54(3)46(58)44-37(39)19-22-50-44)61-35-14-9-32(10-15-35)55(4)33-20-23-56(24-21-33)43-18-16-41(52-53-43)45(57)51-31-7-12-34(13-8-31)60-36-11-5-29(27-49)40(48)26-36/h5-6,9-11,14-19,22,25-26,28,31,33-34,50,59H,7-8,12-13,20-21,23-24H2,1-4H3,(H,51,57)	RKKZZICTIHCCLB-UHFFFAOYSA-N	79947	US20250388575, Compound I-137	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79947	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79947&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			16656172	252656591							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124116	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c2cc[nH]c2c1=O	InChI=1S/C48H50ClN7O5/c1-48(2,59)33-9-18-43(39(26-33)40-29-55(3)47(58)45-38(40)20-23-51-45)61-36-12-6-30(7-13-36)4-5-31-21-24-56(25-22-31)44-19-17-42(53-54-44)46(57)52-34-10-15-35(16-11-34)60-37-14-8-32(28-50)41(49)27-37/h6-9,12-14,17-20,23,26-27,29,31,34-35,51,59H,4-5,10-11,15-16,21-22,24-25H2,1-3H3,(H,52,57)	FVVPXQWBCYXCAL-UHFFFAOYSA-N	79935	US20250388575, Compound I-102	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79935	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79935&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			24816908	252656579							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124117	CCS(=O)(=O)c1ccc(Oc2cccc(CCCOC3CC4(C3)CN(c3ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn3)C4)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C49H49ClFN7O7S/c1-3-66(61,62)36-15-17-42(38(23-36)39-27-57(2)48(60)46-37(39)19-20-53-46)65-43-8-4-6-30(45(43)51)7-5-21-63-35-24-49(25-35)28-58(29-49)44-18-16-41(55-56-44)47(59)54-32-10-13-33(14-11-32)64-34-12-9-31(26-52)40(50)22-34/h4,6,8-9,12,15-20,22-23,27,32-33,35,53H,3,5,7,10-11,13-14,21,24-25,28-29H2,1-2H3,(H,54,59)	JPSJFPRCYNCQSZ-UHFFFAOYSA-N	79948	US20250388575, Compound I-46	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79948	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79948&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			16332146	252656592							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124118	Cn1cc(-c2cc(NC(=O)CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O	InChI=1S/C46H43ClF2N8O5/c1-56-26-36(34-16-19-51-44(34)46(56)60)35-23-31(7-13-40(35)62-41-12-4-29(48)22-38(41)49)52-43(58)15-2-27-17-20-57(21-18-27)42-14-11-39(54-55-42)45(59)53-30-5-9-32(10-6-30)61-33-8-3-28(25-50)37(47)24-33/h3-4,7-8,11-14,16,19,22-24,26-27,30,32,51H,2,5-6,9-10,15,17-18,20-21H2,1H3,(H,52,58)(H,53,59)	FBNILPPTMWVIGK-UHFFFAOYSA-N	79949	US20250388575, Compound I-213	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79949	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79949&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			16309185	252656593							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124119	Cn1cc(-c2cc(S(C)(=O)=O)ccc2Oc2cccc(CCCC3CCN(c4ncc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2F)c2cc[nH]c2c1=O	InChI=1S/C47H47ClFN7O6S/c1-55-28-39(37-17-20-51-44(37)46(55)58)38-24-36(63(2,59)60)15-16-41(38)62-42-8-4-7-30(43(42)49)6-3-5-29-18-21-56(22-19-29)47-52-26-32(27-53-47)45(57)54-33-10-13-34(14-11-33)61-35-12-9-31(25-50)40(48)23-35/h4,7-9,12,15-17,20,23-24,26-29,33-34,51H,3,5-6,10-11,13-14,18-19,21-22H2,1-2H3,(H,54,57)	CKRQJRIWVYTQTI-UHFFFAOYSA-N	79950	US20250388575, Compound I-234	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79950	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79950&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			9684435	252656594							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124120	Cn1cc(-c2cc(S(=O)(=O)CCCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O	InChI=1S/C47H46ClF2N7O7S/c1-56-28-38(36-16-19-52-45(36)47(56)59)37-26-35(11-14-42(37)64-43-13-5-30(49)24-40(43)50)65(60,61)23-3-2-22-62-32-17-20-57(21-18-32)44-15-12-41(54-55-44)46(58)53-31-6-9-33(10-7-31)63-34-8-4-29(27-51)39(48)25-34/h4-5,8,11-16,19,24-26,28,31-33,52H,2-3,6-7,9-10,17-18,20-23H2,1H3,(H,53,58)	YMPBTVHKBRRYHU-UHFFFAOYSA-N	79951	US20250388575, Compound I-92	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79951	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79951&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			4879906	252656595							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124121	CCS(=O)(=O)Cc1ccc(Oc2cccc(CCCCC3CCN(c4ncc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C50H54ClN7O6S/c1-3-65(61,62)32-35-11-18-46(43(26-35)44-31-57(2)49(60)47-42(44)19-22-53-47)64-40-10-6-9-34(25-40)8-5-4-7-33-20-23-58(24-21-33)50-54-29-37(30-55-50)48(59)56-38-13-16-39(17-14-38)63-41-15-12-36(28-52)45(51)27-41/h6,9-12,15,18-19,22,25-27,29-31,33,38-39,53H,3-5,7-8,13-14,16-17,20-21,23-24,32H2,1-2H3,(H,56,59)	ZLZVMUYNIGEFMP-UHFFFAOYSA-N	79937	US20250388575, Compound I-158	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79937	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79937&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			24817165	252656581							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124122	CCS(=O)(=O)c1ccc(OCCCCCC2CCN(c3ccc(C(=O)N[C@H]4CC[C@H](Oc5ccc(C#N)c(Cl)c5)CC4)nn3)CC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C44H50ClN7O6S/c1-3-59(55,56)34-14-16-40(36(26-34)37-28-51(2)44(54)42-35(37)18-21-47-42)57-24-6-4-5-7-29-19-22-52(23-20-29)41-17-15-39(49-50-41)43(53)48-31-9-12-32(13-10-31)58-33-11-8-30(27-46)38(45)25-33/h8,11,14-18,21,25-26,28-29,31-32,47H,3-7,9-10,12-13,19-20,22-24H2,1-2H3,(H,48,53)	XIFXBDMZHVQEEB-UHFFFAOYSA-N	79952	US20250388575, Compound I-231	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79952	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79952&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			91898290	252656596							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124123	CCS(=O)(=O)c1ccc(Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H48ClN7O6S/c1-3-62(58,59)37-16-18-43(39(27-37)40-29-54(2)47(57)45-38(40)20-23-50-45)61-35-11-6-30(7-12-35)4-5-31-21-24-55(25-22-31)44-19-17-42(52-53-44)46(56)51-33-9-14-34(15-10-33)60-36-13-8-32(28-49)41(48)26-36/h6-8,11-13,16-20,23,26-27,29,31,33-34,50H,3-5,9-10,14-15,21-22,24-25H2,1-2H3,(H,51,56)	KLDHUOQEOZOVDJ-UHFFFAOYSA-N	79953	US20250388575, Compound I-50	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79953	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79953&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			42600974	252656597							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124124	CCS(=O)(=O)c1ccc(Oc2cccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H47ClFN7O6S/c1-3-63(59,60)35-15-17-41(37(26-35)38-28-55(2)47(58)45-36(38)19-22-51-45)62-42-6-4-5-30(44(42)49)8-7-29-20-23-56(24-21-29)43-18-16-40(53-54-43)46(57)52-32-10-13-33(14-11-32)61-34-12-9-31(27-50)39(48)25-34/h4-6,9,12,15-19,22,25-26,28-29,32-33,51H,3,7-8,10-11,13-14,20-21,23-24H2,1-2H3,(H,52,57)	CFNIRKKGKRHUJK-UHFFFAOYSA-N	79954	US20250388575, Compound I-51	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79954	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79954&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			44142309	252656598							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124125	CCS(=O)(=O)c1ccc(Oc2cccc(CCCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H49ClFN7O6S/c1-3-64(60,61)36-16-18-42(38(27-36)39-29-56(2)48(59)46-37(39)20-23-52-46)63-43-9-5-8-31(45(43)50)7-4-6-30-21-24-57(25-22-30)44-19-17-41(54-55-44)47(58)53-33-11-14-34(15-12-33)62-35-13-10-32(28-51)40(49)26-35/h5,8-10,13,16-20,23,26-27,29-30,33-34,52H,3-4,6-7,11-12,14-15,21-22,24-25H2,1-2H3,(H,53,58)	HDYBWMRDCFUMEP-UHFFFAOYSA-N	79956	US20250388575, Compound I-52	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79956	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79956&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			44142353	252656600							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124126	Cn1cc(-c2cc(C(C)(C)O)ccc2OC2CCC(CCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)C(F)N2F)c2cc[nH]c2c1=O	InChI=1S/C47H53ClF2N8O6/c1-47(2,61)30-6-13-40(36(24-30)37-27-56(3)46(60)43-35(37)16-20-52-43)64-42-15-5-28(44(49)58(42)50)19-23-62-32-17-21-57(22-18-32)41-14-12-39(54-55-41)45(59)53-31-7-10-33(11-8-31)63-34-9-4-29(26-51)38(48)25-34/h4,6,9,12-14,16,20,24-25,27-28,31-33,42,44,52,61H,5,7-8,10-11,15,17-19,21-23H2,1-3H3,(H,53,59)	KKPMLBUAUOQRTE-UHFFFAOYSA-N	79957	US20250388575, Compound I-108	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79957	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79957&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			44142359	252656601							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124127	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2c(F)cc(CCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2F)c2cc[nH]c2c1=O	InChI=1S/C48H48ClF2N7O6/c1-48(2,61)30-5-12-42(36(24-30)37-27-57(3)47(60)44-35(37)14-18-53-44)64-45-39(50)22-28(23-40(45)51)17-21-62-32-15-19-58(20-16-32)43-13-11-41(55-56-43)46(59)54-31-6-9-33(10-7-31)63-34-8-4-29(26-52)38(49)25-34/h4-5,8,11-14,18,22-25,27,31-33,53,61H,6-7,9-10,15-17,19-21H2,1-3H3,(H,54,59)	MZUGIDOHZCAPFV-UHFFFAOYSA-N	79958	US20250388575, Compound I-109	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79958	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79958&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			44142494	252656602							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124128	CCS(=O)(=O)c1ccc(Oc2ccc(N3CC4(CCN(c5ccc(C(=O)N[C@H]6CC[C@H](Oc7ccc(C#N)c(Cl)c7)CC6)nn5)CC4)C3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H47ClN8O6S/c1-3-63(59,60)36-14-16-42(38(25-36)39-27-54(2)46(58)44-37(39)18-21-50-44)62-34-12-7-32(8-13-34)56-28-47(29-56)19-22-55(23-20-47)43-17-15-41(52-53-43)45(57)51-31-5-10-33(11-6-31)61-35-9-4-30(26-49)40(48)24-35/h4,7-9,12-18,21,24-25,27,31,33,50H,3,5-6,10-11,19-20,22-23,28-29H2,1-2H3,(H,51,57)	SUYILVBAYAQMKD-UHFFFAOYSA-N	79959	US20250388575, Compound I-90	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79959	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79959&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			44144121	252656603							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124129	CCS(=O)(=O)c1ccc(Oc2ccc(COC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c(F)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C46H44ClF2N7O7S/c1-3-64(59,60)33-11-14-39(35(23-33)36-25-55(2)46(58)44-34(36)16-19-51-44)63-40-13-5-28(42(48)43(40)49)26-61-30-17-20-56(21-18-30)41-15-12-38(53-54-41)45(57)52-29-6-9-31(10-7-29)62-32-8-4-27(24-50)37(47)22-32/h4-5,8,11-16,19,22-23,25,29-31,51H,3,6-7,9-10,17-18,20-21,26H2,1-2H3,(H,52,57)	KKYNFRJMDGGOPY-UHFFFAOYSA-N	79960	US20250388575, Compound I-53	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79960	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79960&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			1084866	252656604							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124130	CCS(=O)(=O)c1ccc(Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c(F)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H47ClFN7O6S/c1-3-63(59,60)36-14-16-43(38(26-36)39-28-55(2)47(58)45-37(39)18-21-51-45)62-35-10-6-30(41(49)25-35)5-4-29-19-22-56(23-20-29)44-17-15-42(53-54-44)46(57)52-32-8-12-33(13-9-32)61-34-11-7-31(27-50)40(48)24-34/h6-7,10-11,14-18,21,24-26,28-29,32-33,51H,3-5,8-9,12-13,19-20,22-23H2,1-2H3,(H,52,57)	IQUWQKHDGFVMKS-UHFFFAOYSA-N	79961	US20250388575, Compound I-54	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79961	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79961&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			4537700	252656605							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124131	CCS(=O)(=O)c1ccc(Oc2cccc(CCN3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C46H46ClFN8O6S/c1-3-63(59,60)34-13-15-40(36(26-34)37-28-54(2)46(58)44-35(37)17-19-50-44)62-41-6-4-5-29(43(41)48)18-20-55-21-23-56(24-22-55)42-16-14-39(52-53-42)45(57)51-31-8-11-32(12-9-31)61-33-10-7-30(27-49)38(47)25-33/h4-7,10,13-17,19,25-26,28,31-32,50H,3,8-9,11-12,18,20-24H2,1-2H3,(H,51,57)	TWPMQVDMTCLGIV-UHFFFAOYSA-N	79962	US20250388575, Compound I-55	Bromodomain-containing protein 4 [58-164]	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79962	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79962&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			44201568	252656606							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124132	CCS(=O)(=O)c1ccc(Oc2cccc(OCCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H47ClFN7O7S/c1-3-64(59,60)34-13-15-40(36(26-34)37-28-55(2)47(58)45-35(37)17-21-51-45)63-42-6-4-5-41(44(42)49)61-24-20-29-18-22-56(23-19-29)43-16-14-39(53-54-43)46(57)52-31-8-11-32(12-9-31)62-33-10-7-30(27-50)38(48)25-33/h4-7,10,13-17,21,25-26,28-29,31-32,51H,3,8-9,11-12,18-20,22-24H2,1-2H3,(H,52,57)	SUKVXMZTLBCQHU-UHFFFAOYSA-N	79963	US20250388575, Compound I-42	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79963	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79963&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			44201634	252656607							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124133	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2cc(F)c(CCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c(F)c2)c2cc[nH]c2c1=O	InChI=1S/C48H48ClF2N7O6/c1-48(2,61)29-5-12-43(37(22-29)38-27-57(3)47(60)45-35(38)14-18-53-45)64-34-24-40(50)36(41(51)25-34)17-21-62-31-15-19-58(20-16-31)44-13-11-42(55-56-44)46(59)54-30-6-9-32(10-7-30)63-33-8-4-28(26-52)39(49)23-33/h4-5,8,11-14,18,22-25,27,30-32,53,61H,6-7,9-10,15-17,19-21H2,1-3H3,(H,54,59)	UQJUZZTZRVKDOQ-UHFFFAOYSA-N	79964	US20250388575, Compound I-110	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79964	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79964&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			44202616	252656608							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124134	CCS(=O)(=O)c1ccc(Oc2ccc(CN3CC4(C3)CN(c3ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn3)C4)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C46H45ClN8O6S/c1-3-62(58,59)35-14-16-41(37(21-35)38-24-53(2)45(57)43-36(38)18-19-49-43)61-33-9-4-29(5-10-33)23-54-25-46(26-54)27-55(28-46)42-17-15-40(51-52-42)44(56)50-31-7-12-32(13-8-31)60-34-11-6-30(22-48)39(47)20-34/h4-6,9-11,14-21,24,31-32,49H,3,7-8,12-13,23,25-28H2,1-2H3,(H,50,56)	FYAGCTZMDSVJFI-UHFFFAOYSA-N	79965	US20250388575, Compound I-56	Bromodomain-containing protein 4 [58-164]	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79965	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79965&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			2315573	252656609							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124135	CCS(=O)(=O)c1ccc(Oc2ccc(CN3CC4(CCN(c5ccc(C(=O)N[C@H]6CC[C@H](Oc7ccc(C#N)c(Cl)c7)CC6)nn5)CC4)C3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H49ClN8O6S/c1-3-64(60,61)37-14-16-43(39(25-37)40-28-55(2)47(59)45-38(40)18-21-51-45)63-35-9-4-31(5-10-35)27-56-29-48(30-56)19-22-57(23-20-48)44-17-15-42(53-54-44)46(58)52-33-7-12-34(13-8-33)62-36-11-6-32(26-50)41(49)24-36/h4-6,9-11,14-18,21,24-25,28,33-34,51H,3,7-8,12-13,19-20,22-23,27,29-30H2,1-2H3,(H,52,58)	VAFCACGNKWELFU-UHFFFAOYSA-N	79966	US20250388575, Compound I-57	Bromodomain-containing protein 4 [58-164]	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79966	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79966&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			16656525	252656610							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124136	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2F)c2cc[nH]c2c1=O	InChI=1S/C48H49ClFN7O5/c1-48(2,60)32-8-16-42(37(25-32)38-28-56(3)47(59)45-36(38)18-21-52-45)62-43-15-6-30(24-40(43)50)5-4-29-19-22-57(23-20-29)44-17-14-41(54-55-44)46(58)53-33-9-12-34(13-10-33)61-35-11-7-31(27-51)39(49)26-35/h6-8,11,14-18,21,24-26,28-29,33-34,52,60H,4-5,9-10,12-13,19-20,22-23H2,1-3H3,(H,53,58)	LUJFPGTZCISWTG-UHFFFAOYSA-N	79967	US20250388575, Compound I-111	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79967	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79967&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			44601856	252656611							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124137	CCS(=O)(=O)c1ccc(Oc2cc(F)c(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H46ClF2N7O6S/c1-3-64(60,61)34-12-14-42(36(24-34)37-27-56(2)47(59)45-35(37)16-19-52-45)63-43-25-39(49)29(22-40(43)50)5-4-28-17-20-57(21-18-28)44-15-13-41(54-55-44)46(58)53-31-7-10-32(11-8-31)62-33-9-6-30(26-51)38(48)23-33/h6,9,12-16,19,22-25,27-28,31-32,52H,3-5,7-8,10-11,17-18,20-21H2,1-2H3,(H,53,58)	UKVKZGUDRDODLD-UHFFFAOYSA-N	81250	US20250388575, Compound I-59	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81250	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81250&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			386817	252657757							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124138	CCS(=O)(=O)Cc1ccc(Oc2cccc(OC(C)(C)CCC3CCN(c4ncc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C51H56ClN7O7S/c1-5-67(62,63)32-34-9-16-46(43(25-34)44-31-58(4)49(61)47-42(44)18-22-54-47)65-39-7-6-8-41(26-39)66-51(2,3)21-17-33-19-23-59(24-20-33)50-55-29-36(30-56-50)48(60)57-37-11-14-38(15-12-37)64-40-13-10-35(28-53)45(52)27-40/h6-10,13,16,18,22,25-27,29-31,33,37-38,54H,5,11-12,14-15,17,19-21,23-24,32H2,1-4H3,(H,57,60)	JAHPQJHOZHKKGB-UHFFFAOYSA-N	81829	US20250388575, Compound I-154	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81829	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81829&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			23626397	131342403							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124139	CCS(=O)(=O)Nc1ccc(Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H49ClN8O6S/c1-3-63(59,60)54-34-11-18-43(39(26-34)40-29-55(2)47(58)45-38(40)20-23-50-45)62-36-12-6-30(7-13-36)4-5-31-21-24-56(25-22-31)44-19-17-42(52-53-44)46(57)51-33-9-15-35(16-10-33)61-37-14-8-32(28-49)41(48)27-37/h6-8,11-14,17-20,23,26-27,29,31,33,35,50,54H,3-5,9-10,15-16,21-22,24-25H2,1-2H3,(H,51,57)	SKLOAVWFSCZBKK-UHFFFAOYSA-N	81830	US20250388575, Compound I-38	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81830	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81830&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			23625933	131342404							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124140	Cn1cc(-c2cc(NC(=O)N3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O	InChI=1S/C43H38ClF2N9O5/c1-53-24-33(31-14-15-48-40(31)42(53)57)32-21-28(6-12-37(32)60-38-11-3-26(45)20-35(38)46)50-43(58)55-18-16-54(17-19-55)39-13-10-36(51-52-39)41(56)49-27-4-8-29(9-5-27)59-30-7-2-25(23-47)34(44)22-30/h2-3,6-7,10-15,20-22,24,27,29,48H,4-5,8-9,16-19H2,1H3,(H,49,56)(H,50,58)	JBHHVQTYEUEOPT-UHFFFAOYSA-N	81831	US20250388575, Compound I-218	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81831&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			23626398	131342405							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124141	CCS(=O)(=O)c1ccc(Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)nc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C46H47ClN8O6S/c1-3-62(58,59)36-14-16-42(38(25-36)39-28-54(2)46(57)44-37(39)18-21-49-44)61-35-13-7-31(50-27-35)6-4-29-19-22-55(23-20-29)43-17-15-41(52-53-43)45(56)51-32-8-11-33(12-9-32)60-34-10-5-30(26-48)40(47)24-34/h5,7,10,13-18,21,24-25,27-29,32-33,49H,3-4,6,8-9,11-12,19-20,22-23H2,1-2H3,(H,51,56)	ISEBUFYCCAJXPV-UHFFFAOYSA-N	81832	US20250388575, Compound I-219	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81832	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81832&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			23626552	131342406							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124142	Cn1cc(-c2cc(C(C)(C)O)ccc2OC2CC3(C2)CN(CCC2CCN(c4ncc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC2)C3)c2cc[nH]c2c1=O	InChI=1S/C47H54ClN9O5/c1-46(2,60)31-5-11-41(37(20-31)38-26-55(3)44(59)42-36(38)12-16-50-42)62-35-22-47(23-35)27-56(28-47)17-13-29-14-18-57(19-15-29)45-51-25-40(53-54-45)43(58)52-32-6-9-33(10-7-32)61-34-8-4-30(24-49)39(48)21-34/h4-5,8,11-12,16,20-21,25-26,29,32-33,35,50,60H,6-7,9-10,13-15,17-19,22-23,27-28H2,1-3H3,(H,52,58)	DFZRCFUJEZNTNO-UHFFFAOYSA-N	81833	US20250388575, Compound I-162	Bromodomain-containing protein 4 [58-164]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81833	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1168&target=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81833&enzyme=Bromodomain-containing+protein+4+%5B58-164%5D&column=ki&startPg=0&Increment=50&submit=Search			23625934	131342407							1	RQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL	4BJX,4UYD,9C5V,7FH2,6IN1,6AJZ,6AJY,6AJX,6AJW,6AJV,5YQX,7KHL,7KHH,5VOM,6ZCI,5Y8C,9NN5,8ZMB,8ZM8,8WY7,8WY3,8WXY,8K14,7YL2,7WL4,7WKY,7WJS,7V2J,7V1U,7DHS,5Z1T,5Z1S,5Z1R,5Y94,5Y93,5Y8Z,5Y8Y,5Y8W,5D0C,5CY9,5CTL,5CS8,5CRZ,5CRM,5CQT,5CPE,5CP5,5COI,6VIZ,6VIW,9MPI,6DNE,7TV0,7TUQ,5U2F,5U2E,4KV1,9NNT,9MXK,6MAU,6E4A,6CZV,6CZU,5DW2,4YH4,4YH3,5U28,8Q34,6X7C,6X7B,6ULV,6ULS,6U8M,6U8G,6U74,6U72,6U6K,9RSD,9RSC,6DJC,6X7D,6WW8,4ZW1,5KU3,5I88,5I80,4DON,5HM0,5HLS,4LRG,4LR6,4Z1Q,6DL2,4Z1S,4X2I,3MUL,3MUK,3JVK,3JVJ,6CD4,5WA5,5W55,7WWZ,6VUJ,6VUF,6VUC,6VUB,6PSB,6PS9,6PRT,9ZG4,6CJ2,6CJ1,6CIS,5HQ6,4QR5,4QR4,4QR3,8YMI,8YMH,8YMG,8YMF,8YME,6WVX,8OV6,4C66,9SAI,9SAF,9R5N,9QW8,9QNV,9IV5,9HT2,9HT1,9HT0,9FXP,9FWX,9FBY,9F1N,9F1M,9F1L,9F1K,8V9F,8V92,8QAR,8QAP,8QAN,8QAL,8PXN,8PXM,8PXA,8PIQ,8P9L,8P9K,8P9J,8P9I,8P9H,8P9G,8P9F,8FVK,8EWV,8EAD,8E3W,8E17,8DYR,8BEB,8BDS,8B98,8B96,7UTY,7UGF,7RXT,7RXS,7RXR,7RN2,7RMD,7RJR,7RJQ,7RJP,7RJO,7REM,7REL,7R9C,7R5B,7QDL,7Q3F,7P6Y,7P6W,7P6V,7O18,7MRB,7MRA,7MR9,7MR8,7MR7,7MR6,7MR5,7MLS,7MLR,7MLQ,7M16,7LH8,7L9M,7K6H,7K6G,7B1T,7AXR,7AJN,7A9U,6ZF9,6ZEL,6ZED,6ZB3,6Z7M,6Z7L,6Z7G,6YQZ,6YQP,6YQO,6YQN,6YIN,6XVC,6XV7,6XV3,6XUZ,6WGX,6V1U,6V1L,6V1K,6V0U,6UWX,6UWU,6UVM,6UVJ,6U0D,6TPZ,6TPY,6TPX,6SWQ,6SWN,6SE4,6SB8,6SAJ,6SAH,6SA3,6SA2,6S6K,6S4B,6S25,6RWJ,6Q3Z,6Q3Y,6MH7,6MH1,6KEG,6KEF,6KEE,6KED,6I7Y,6I7X,6HOV,6HDQ,6G0S,6G0R,6G0Q,6G0P,6G0O,6G0H,6G0G,6G0F,6G0E,6G0D,6FT4,6FT3,6FSY,6FO5,6FNX,6DML,6DMJ,6CIY,6CD5,6BOY,6BNB,6BN9,6BN7,6AFR,5Z9K,5Z90,5Z8Z,5Z8R,5Z8G,5YOV,5YOU,5WMA,5VBP,5VBO,5V67,5ULA,5TI7,5TI6,5TI5,5TI4,5TI3,5TI2,5OWW,5OWM,5OVB,5O97,5NNG,5NNF,5NNE,5NND,5NNC,5N2M,5MLI,5MKZ,5M3A,5M39,5LUU,5LJ2,5LJ1,5KJ0,5KHM,5KDH,5IGK,5HQ5,5HCL,5FBX,5F63,5F62,5F61,5F60,5F5Z,5EIS,5EI4,5EGU,5E0R,5DLZ,5DLX,5D3T,5D3R,5D3P,5D3L,5D26,5CFW,5BT4,5AD3,5AD2,5ACY,5A85,4ZC9,4XYA,4XY9,4WIV,4WHW,4UIZ,4UIY,4QZS,4QB3,4PS5,4PCI,4PCE,4OGJ,4OGI,4O7F,4O7E,4O7C,4O7B,4O7A,4O78,4O77,4O76,4O75,4O74	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124143	CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOCCOCCOCCOCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C55H65ClN8O12S/c1-3-77(67,68)62-40-10-15-51(47(33-40)48-37-63(2)55(66)53-46(48)17-20-58-53)76-44-6-4-5-43(34-44)74-32-30-72-28-26-70-24-23-69-25-27-71-29-31-73-41-18-21-64(22-19-41)52-16-14-50(60-61-52)54(65)59-39-8-12-42(13-9-39)75-45-11-7-38(36-57)49(56)35-45/h4-7,10-11,14-17,20,33-35,37,39,41-42,58,62H,3,8-9,12-13,18-19,21-32H2,1-2H3,(H,59,65)	DJSPPYLXDYITKE-UHFFFAOYSA-N	79926	US20250388575, Compound I-3	Bromodomain-containing protein 4 [353-454]	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79926	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79926&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			15990985	252656570							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124144	CCS(=O)(=O)Nc1ccc(Oc2ccc(OCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C46H47ClN8O7S/c1-3-63(58,59)53-32-7-16-42(38(24-32)39-27-54(2)46(57)44-37(39)18-21-49-44)62-35-13-11-33(12-14-35)60-28-29-19-22-55(23-20-29)43-17-15-41(51-52-43)45(56)50-31-5-9-34(10-6-31)61-36-8-4-30(26-48)40(47)25-36/h4,7-8,11-18,21,24-25,27,29,31,34,49,53H,3,5-6,9-10,19-20,22-23,28H2,1-2H3,(H,50,56)	QNPJMLJOWSSDTA-UHFFFAOYSA-N	79939	US20250388575, Compound I-33	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79939	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79939&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			1950409	252656583							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124145	CCS(=O)(=O)c1ccc(Oc2cccc(OCCCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H49ClFN7O7S/c1-3-65(60,61)35-15-17-41(37(27-35)38-29-56(2)48(59)46-36(38)19-22-52-46)64-43-8-4-7-42(45(43)50)62-25-5-6-30-20-23-57(24-21-30)44-18-16-40(54-55-44)47(58)53-32-10-13-33(14-11-32)63-34-12-9-31(28-51)39(49)26-34/h4,7-9,12,15-19,22,26-27,29-30,32-33,52H,3,5-6,10-11,13-14,20-21,23-25H2,1-2H3,(H,53,58)	BSBAKUWVVBPLLJ-UHFFFAOYSA-N	79940	US20250388575, Compound I-15	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79940	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79940&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			24818804	252656584							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124146	CCS(=O)(=O)Nc1ccc(Oc2ccc(CCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H49ClN8O7S/c1-3-64(59,60)54-33-9-16-43(39(26-33)40-29-55(2)47(58)45-38(40)18-22-50-45)63-36-10-4-30(5-11-36)21-25-61-34-19-23-56(24-20-34)44-17-15-42(52-53-44)46(57)51-32-7-13-35(14-8-32)62-37-12-6-31(28-49)41(48)27-37/h4-6,9-12,15-18,22,26-27,29,32,34-35,50,54H,3,7-8,13-14,19-21,23-25H2,1-2H3,(H,51,57)	HZFCHSMDVKJBNT-UHFFFAOYSA-N	79941	US20250388575, Compound I-35	Bromodomain-containing protein 4 [353-454]	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79941	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79941&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			24819158	252656585							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124147	CCS(=O)(=O)Nc1ccc(Oc2ccc(CCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H51ClN8O7S/c1-3-65(60,61)55-34-11-18-44(40(27-34)41-30-56(2)48(59)46-39(41)20-23-51-46)64-37-12-6-31(7-13-37)5-4-26-62-35-21-24-57(25-22-35)45-19-17-43(53-54-45)47(58)52-33-9-15-36(16-10-33)63-38-14-8-32(29-50)42(49)28-38/h6-8,11-14,17-20,23,27-28,30,33,35-36,51,55H,3-5,9-10,15-16,21-22,24-26H2,1-2H3,(H,52,58)	CRQIIMVPBBDNQB-UHFFFAOYSA-N	79942	US20250388575, Compound I-36	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79942	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79942&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			24819406	252656586							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124148	CCS(=O)(=O)Cc1ccc(Oc2cccc(OCCCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C49H51ClFN7O7S/c1-3-66(61,62)30-32-9-17-42(38(26-32)39-29-57(2)49(60)47-37(39)19-22-53-47)65-44-8-4-7-43(46(44)51)63-25-5-6-31-20-23-58(24-21-31)45-18-16-41(55-56-45)48(59)54-34-11-14-35(15-12-34)64-36-13-10-33(28-52)40(50)27-36/h4,7-10,13,16-19,22,26-27,29,31,34-35,53H,3,5-6,11-12,14-15,20-21,23-25,30H2,1-2H3,(H,54,59)	PDGPUENKHMYNCK-UHFFFAOYSA-N	79943	US20250388575, Compound I-20	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79943	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79943&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			16830239	252656587							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124149	CCS(=O)(=O)Cc1ccc(Oc2cccc(CCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C49H51ClFN7O7S/c1-3-66(61,62)30-31-9-17-43(39(26-31)40-29-57(2)49(60)47-38(40)19-22-53-47)65-44-8-4-6-32(46(44)51)7-5-25-63-35-20-23-58(24-21-35)45-18-16-42(55-56-45)48(59)54-34-11-14-36(15-12-34)64-37-13-10-33(28-52)41(50)27-37/h4,6,8-10,13,16-19,22,26-27,29,34-36,53H,3,5,7,11-12,14-15,20-21,23-25,30H2,1-2H3,(H,54,59)	IHHJMQNFPRLCDB-UHFFFAOYSA-N	79944	US20250388575, Compound I-29	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79944	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79944&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			24979400	252656588							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124150	CCS(=O)(=O)Nc1ccc(OCC(OCCOC2CCN(c3ccc(C(=O)N[C@H]4CC[C@H](Oc5ccc(C#N)c(Cl)c5)CC4)nn3)CC2)C2CC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C46H53ClN8O8S/c1-3-64(58,59)53-32-9-14-41(37(24-32)38-27-54(2)46(57)44-36(38)16-19-49-44)62-28-42(29-4-5-29)61-23-22-60-33-17-20-55(21-18-33)43-15-13-40(51-52-43)45(56)50-31-7-11-34(12-8-31)63-35-10-6-30(26-48)39(47)25-35/h6,9-10,13-16,19,24-25,27,29,31,33-34,42,49,53H,3-5,7-8,11-12,17-18,20-23,28H2,1-2H3,(H,50,56)	VHBRMSLGESEWMS-UHFFFAOYSA-N	79945	US20250388575, Compound I-30	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79945	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79945&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			24979750	252656589							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124151	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2ccc(OC3CN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)C3)cc2)c2cc[nH]c2c1=O	InChI=1S/C44H42ClN7O6/c1-44(2,55)27-5-16-39(35(20-27)36-25-51(3)43(54)41-34(36)18-19-47-41)58-31-13-11-30(12-14-31)57-33-23-52(24-33)40-17-15-38(49-50-40)42(53)48-28-6-9-29(10-7-28)56-32-8-4-26(22-46)37(45)21-32/h4-5,8,11-21,25,28-29,33,47,55H,6-7,9-10,23-24H2,1-3H3,(H,48,53)	YERIFSQXBJEXQC-UHFFFAOYSA-N	79946	US20250388575, Compound I-95	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79946	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79946&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			24982063	252656590							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124152	CN(c1ccc(Oc2ccc(C(C)(C)O)cc2-c2cn(C)c(=O)c3[nH]ccc23)cc1)C1CCN(c2ccc(C(=O)N[C@H]3CC[C@H](Oc4ccc(C#N)c(Cl)c4)CC3)nn2)CC1	InChI=1S/C47H49ClN8O5/c1-47(2,59)30-6-17-42(38(25-30)39-28-54(3)46(58)44-37(39)19-22-50-44)61-35-14-9-32(10-15-35)55(4)33-20-23-56(24-21-33)43-18-16-41(52-53-43)45(57)51-31-7-12-34(13-8-31)60-36-11-5-29(27-49)40(48)26-36/h5-6,9-11,14-19,22,25-26,28,31,33-34,50,59H,7-8,12-13,20-21,23-24H2,1-4H3,(H,51,57)	RKKZZICTIHCCLB-UHFFFAOYSA-N	79947	US20250388575, Compound I-137	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79947	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79947&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			16656172	252656591							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124153	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c2cc[nH]c2c1=O	InChI=1S/C48H50ClN7O5/c1-48(2,59)33-9-18-43(39(26-33)40-29-55(3)47(58)45-38(40)20-23-51-45)61-36-12-6-30(7-13-36)4-5-31-21-24-56(25-22-31)44-19-17-42(53-54-44)46(57)52-34-10-15-35(16-11-34)60-37-14-8-32(28-50)41(49)27-37/h6-9,12-14,17-20,23,26-27,29,31,34-35,51,59H,4-5,10-11,15-16,21-22,24-25H2,1-3H3,(H,52,57)	FVVPXQWBCYXCAL-UHFFFAOYSA-N	79935	US20250388575, Compound I-102	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79935	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79935&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			24816908	252656579							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124154	CCS(=O)(=O)c1ccc(Oc2cccc(CCCOC3CC4(C3)CN(c3ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn3)C4)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C49H49ClFN7O7S/c1-3-66(61,62)36-15-17-42(38(23-36)39-27-57(2)48(60)46-37(39)19-20-53-46)65-43-8-4-6-30(45(43)51)7-5-21-63-35-24-49(25-35)28-58(29-49)44-18-16-41(55-56-44)47(59)54-32-10-13-33(14-11-32)64-34-12-9-31(26-52)40(50)22-34/h4,6,8-9,12,15-20,22-23,27,32-33,35,53H,3,5,7,10-11,13-14,21,24-25,28-29H2,1-2H3,(H,54,59)	JPSJFPRCYNCQSZ-UHFFFAOYSA-N	79948	US20250388575, Compound I-46	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79948	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79948&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			16332146	252656592							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124155	Cn1cc(-c2cc(NC(=O)CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O	InChI=1S/C46H43ClF2N8O5/c1-56-26-36(34-16-19-51-44(34)46(56)60)35-23-31(7-13-40(35)62-41-12-4-29(48)22-38(41)49)52-43(58)15-2-27-17-20-57(21-18-27)42-14-11-39(54-55-42)45(59)53-30-5-9-32(10-6-30)61-33-8-3-28(25-50)37(47)24-33/h3-4,7-8,11-14,16,19,22-24,26-27,30,32,51H,2,5-6,9-10,15,17-18,20-21H2,1H3,(H,52,58)(H,53,59)	FBNILPPTMWVIGK-UHFFFAOYSA-N	79949	US20250388575, Compound I-213	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79949	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79949&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			16309185	252656593							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124156	Cn1cc(-c2cc(S(C)(=O)=O)ccc2Oc2cccc(CCCC3CCN(c4ncc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2F)c2cc[nH]c2c1=O	InChI=1S/C47H47ClFN7O6S/c1-55-28-39(37-17-20-51-44(37)46(55)58)38-24-36(63(2,59)60)15-16-41(38)62-42-8-4-7-30(43(42)49)6-3-5-29-18-21-56(22-19-29)47-52-26-32(27-53-47)45(57)54-33-10-13-34(14-11-33)61-35-12-9-31(25-50)40(48)23-35/h4,7-9,12,15-17,20,23-24,26-29,33-34,51H,3,5-6,10-11,13-14,18-19,21-22H2,1-2H3,(H,54,57)	CKRQJRIWVYTQTI-UHFFFAOYSA-N	79950	US20250388575, Compound I-234	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79950	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79950&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			9684435	252656594							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124157	Cn1cc(-c2cc(S(=O)(=O)CCCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O	InChI=1S/C47H46ClF2N7O7S/c1-56-28-38(36-16-19-52-45(36)47(56)59)37-26-35(11-14-42(37)64-43-13-5-30(49)24-40(43)50)65(60,61)23-3-2-22-62-32-17-20-57(21-18-32)44-15-12-41(54-55-44)46(58)53-31-6-9-33(10-7-31)63-34-8-4-29(27-51)39(48)25-34/h4-5,8,11-16,19,24-26,28,31-33,52H,2-3,6-7,9-10,17-18,20-23H2,1H3,(H,53,58)	YMPBTVHKBRRYHU-UHFFFAOYSA-N	79951	US20250388575, Compound I-92	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79951	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79951&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			4879906	252656595							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124158	CCS(=O)(=O)Cc1ccc(Oc2cccc(CCCCC3CCN(c4ncc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C50H54ClN7O6S/c1-3-65(61,62)32-35-11-18-46(43(26-35)44-31-57(2)49(60)47-42(44)19-22-53-47)64-40-10-6-9-34(25-40)8-5-4-7-33-20-23-58(24-21-33)50-54-29-37(30-55-50)48(59)56-38-13-16-39(17-14-38)63-41-15-12-36(28-52)45(51)27-41/h6,9-12,15,18-19,22,25-27,29-31,33,38-39,53H,3-5,7-8,13-14,16-17,20-21,23-24,32H2,1-2H3,(H,56,59)	ZLZVMUYNIGEFMP-UHFFFAOYSA-N	79937	US20250388575, Compound I-158	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79937	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79937&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			24817165	252656581							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124159	CCS(=O)(=O)c1ccc(OCCCCCC2CCN(c3ccc(C(=O)N[C@H]4CC[C@H](Oc5ccc(C#N)c(Cl)c5)CC4)nn3)CC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C44H50ClN7O6S/c1-3-59(55,56)34-14-16-40(36(26-34)37-28-51(2)44(54)42-35(37)18-21-47-42)57-24-6-4-5-7-29-19-22-52(23-20-29)41-17-15-39(49-50-41)43(53)48-31-9-12-32(13-10-31)58-33-11-8-30(27-46)38(45)25-33/h8,11,14-18,21,25-26,28-29,31-32,47H,3-7,9-10,12-13,19-20,22-24H2,1-2H3,(H,48,53)	XIFXBDMZHVQEEB-UHFFFAOYSA-N	79952	US20250388575, Compound I-231	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79952	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79952&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			91898290	252656596							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124160	CCS(=O)(=O)c1ccc(Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H48ClN7O6S/c1-3-62(58,59)37-16-18-43(39(27-37)40-29-54(2)47(57)45-38(40)20-23-50-45)61-35-11-6-30(7-12-35)4-5-31-21-24-55(25-22-31)44-19-17-42(52-53-44)46(56)51-33-9-14-34(15-10-33)60-36-13-8-32(28-49)41(48)26-36/h6-8,11-13,16-20,23,26-27,29,31,33-34,50H,3-5,9-10,14-15,21-22,24-25H2,1-2H3,(H,51,56)	KLDHUOQEOZOVDJ-UHFFFAOYSA-N	79953	US20250388575, Compound I-50	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79953	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79953&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			42600974	252656597							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124161	CCS(=O)(=O)c1ccc(Oc2cccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H47ClFN7O6S/c1-3-63(59,60)35-15-17-41(37(26-35)38-28-55(2)47(58)45-36(38)19-22-51-45)62-42-6-4-5-30(44(42)49)8-7-29-20-23-56(24-21-29)43-18-16-40(53-54-43)46(57)52-32-10-13-33(14-11-32)61-34-12-9-31(27-50)39(48)25-34/h4-6,9,12,15-19,22,25-26,28-29,32-33,51H,3,7-8,10-11,13-14,20-21,23-24H2,1-2H3,(H,52,57)	CFNIRKKGKRHUJK-UHFFFAOYSA-N	79954	US20250388575, Compound I-51	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79954	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79954&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			44142309	252656598							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124162	CCS(=O)(=O)c1ccc(Oc2cccc(CCCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H49ClFN7O6S/c1-3-64(60,61)36-16-18-42(38(27-36)39-29-56(2)48(59)46-37(39)20-23-52-46)63-43-9-5-8-31(45(43)50)7-4-6-30-21-24-57(25-22-30)44-19-17-41(54-55-44)47(58)53-33-11-14-34(15-12-33)62-35-13-10-32(28-51)40(49)26-35/h5,8-10,13,16-20,23,26-27,29-30,33-34,52H,3-4,6-7,11-12,14-15,21-22,24-25H2,1-2H3,(H,53,58)	HDYBWMRDCFUMEP-UHFFFAOYSA-N	79956	US20250388575, Compound I-52	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79956	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79956&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			44142353	252656600							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124163	Cn1cc(-c2cc(C(C)(C)O)ccc2OC2CCC(CCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)C(F)N2F)c2cc[nH]c2c1=O	InChI=1S/C47H53ClF2N8O6/c1-47(2,61)30-6-13-40(36(24-30)37-27-56(3)46(60)43-35(37)16-20-52-43)64-42-15-5-28(44(49)58(42)50)19-23-62-32-17-21-57(22-18-32)41-14-12-39(54-55-41)45(59)53-31-7-10-33(11-8-31)63-34-9-4-29(26-51)38(48)25-34/h4,6,9,12-14,16,20,24-25,27-28,31-33,42,44,52,61H,5,7-8,10-11,15,17-19,21-23H2,1-3H3,(H,53,59)	KKPMLBUAUOQRTE-UHFFFAOYSA-N	79957	US20250388575, Compound I-108	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79957	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79957&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			44142359	252656601							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124164	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2c(F)cc(CCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2F)c2cc[nH]c2c1=O	InChI=1S/C48H48ClF2N7O6/c1-48(2,61)30-5-12-42(36(24-30)37-27-57(3)47(60)44-35(37)14-18-53-44)64-45-39(50)22-28(23-40(45)51)17-21-62-32-15-19-58(20-16-32)43-13-11-41(55-56-43)46(59)54-31-6-9-33(10-7-31)63-34-8-4-29(26-52)38(49)25-34/h4-5,8,11-14,18,22-25,27,31-33,53,61H,6-7,9-10,15-17,19-21H2,1-3H3,(H,54,59)	MZUGIDOHZCAPFV-UHFFFAOYSA-N	79958	US20250388575, Compound I-109	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79958	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79958&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			44142494	252656602							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124165	CCS(=O)(=O)c1ccc(Oc2ccc(N3CC4(CCN(c5ccc(C(=O)N[C@H]6CC[C@H](Oc7ccc(C#N)c(Cl)c7)CC6)nn5)CC4)C3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H47ClN8O6S/c1-3-63(59,60)36-14-16-42(38(25-36)39-27-54(2)46(58)44-37(39)18-21-50-44)62-34-12-7-32(8-13-34)56-28-47(29-56)19-22-55(23-20-47)43-17-15-41(52-53-43)45(57)51-31-5-10-33(11-6-31)61-35-9-4-30(26-49)40(48)24-35/h4,7-9,12-18,21,24-25,27,31,33,50H,3,5-6,10-11,19-20,22-23,28-29H2,1-2H3,(H,51,57)	SUYILVBAYAQMKD-UHFFFAOYSA-N	79959	US20250388575, Compound I-90	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79959	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79959&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			44144121	252656603							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124166	CCS(=O)(=O)c1ccc(Oc2ccc(COC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c(F)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C46H44ClF2N7O7S/c1-3-64(59,60)33-11-14-39(35(23-33)36-25-55(2)46(58)44-34(36)16-19-51-44)63-40-13-5-28(42(48)43(40)49)26-61-30-17-20-56(21-18-30)41-15-12-38(53-54-41)45(57)52-29-6-9-31(10-7-29)62-32-8-4-27(24-50)37(47)22-32/h4-5,8,11-16,19,22-23,25,29-31,51H,3,6-7,9-10,17-18,20-21,26H2,1-2H3,(H,52,57)	KKYNFRJMDGGOPY-UHFFFAOYSA-N	79960	US20250388575, Compound I-53	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79960	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79960&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			1084866	252656604							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124167	CCS(=O)(=O)c1ccc(Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c(F)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H47ClFN7O6S/c1-3-63(59,60)36-14-16-43(38(26-36)39-28-55(2)47(58)45-37(39)18-21-51-45)62-35-10-6-30(41(49)25-35)5-4-29-19-22-56(23-20-29)44-17-15-42(53-54-44)46(57)52-32-8-12-33(13-9-32)61-34-11-7-31(27-50)40(48)24-34/h6-7,10-11,14-18,21,24-26,28-29,32-33,51H,3-5,8-9,12-13,19-20,22-23H2,1-2H3,(H,52,57)	IQUWQKHDGFVMKS-UHFFFAOYSA-N	79961	US20250388575, Compound I-54	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79961	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79961&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			4537700	252656605							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124168	CCS(=O)(=O)c1ccc(Oc2cccc(CCN3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C46H46ClFN8O6S/c1-3-63(59,60)34-13-15-40(36(26-34)37-28-54(2)46(58)44-35(37)17-19-50-44)62-41-6-4-5-29(43(41)48)18-20-55-21-23-56(24-22-55)42-16-14-39(52-53-42)45(57)51-31-8-11-32(12-9-31)61-33-10-7-30(27-49)38(47)25-33/h4-7,10,13-17,19,25-26,28,31-32,50H,3,8-9,11-12,18,20-24H2,1-2H3,(H,51,57)	TWPMQVDMTCLGIV-UHFFFAOYSA-N	79962	US20250388575, Compound I-55	Bromodomain-containing protein 4 [353-454]	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79962	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79962&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			44201568	252656606							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124169	CCS(=O)(=O)c1ccc(Oc2cccc(OCCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H47ClFN7O7S/c1-3-64(59,60)34-13-15-40(36(26-34)37-28-55(2)47(58)45-35(37)17-21-51-45)63-42-6-4-5-41(44(42)49)61-24-20-29-18-22-56(23-19-29)43-16-14-39(53-54-43)46(57)52-31-8-11-32(12-9-31)62-33-10-7-30(27-50)38(48)25-33/h4-7,10,13-17,21,25-26,28-29,31-32,51H,3,8-9,11-12,18-20,22-24H2,1-2H3,(H,52,57)	SUKVXMZTLBCQHU-UHFFFAOYSA-N	79963	US20250388575, Compound I-42	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79963	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79963&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			44201634	252656607							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124170	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2cc(F)c(CCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c(F)c2)c2cc[nH]c2c1=O	InChI=1S/C48H48ClF2N7O6/c1-48(2,61)29-5-12-43(37(22-29)38-27-57(3)47(60)45-35(38)14-18-53-45)64-34-24-40(50)36(41(51)25-34)17-21-62-31-15-19-58(20-16-31)44-13-11-42(55-56-44)46(59)54-30-6-9-32(10-7-30)63-33-8-4-28(26-52)39(49)23-33/h4-5,8,11-14,18,22-25,27,30-32,53,61H,6-7,9-10,15-17,19-21H2,1-3H3,(H,54,59)	UQJUZZTZRVKDOQ-UHFFFAOYSA-N	79964	US20250388575, Compound I-110	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79964	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79964&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			44202616	252656608							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124171	CCS(=O)(=O)c1ccc(Oc2ccc(CN3CC4(C3)CN(c3ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn3)C4)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C46H45ClN8O6S/c1-3-62(58,59)35-14-16-41(37(21-35)38-24-53(2)45(57)43-36(38)18-19-49-43)61-33-9-4-29(5-10-33)23-54-25-46(26-54)27-55(28-46)42-17-15-40(51-52-42)44(56)50-31-7-12-32(13-8-31)60-34-11-6-30(22-48)39(47)20-34/h4-6,9-11,14-21,24,31-32,49H,3,7-8,12-13,23,25-28H2,1-2H3,(H,50,56)	FYAGCTZMDSVJFI-UHFFFAOYSA-N	79965	US20250388575, Compound I-56	Bromodomain-containing protein 4 [353-454]	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79965	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79965&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			2315573	252656609							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124172	CCS(=O)(=O)c1ccc(Oc2ccc(CN3CC4(CCN(c5ccc(C(=O)N[C@H]6CC[C@H](Oc7ccc(C#N)c(Cl)c7)CC6)nn5)CC4)C3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H49ClN8O6S/c1-3-64(60,61)37-14-16-43(39(25-37)40-28-55(2)47(59)45-38(40)18-21-51-45)63-35-9-4-31(5-10-35)27-56-29-48(30-56)19-22-57(23-20-48)44-17-15-42(53-54-44)46(58)52-33-7-12-34(13-8-33)62-36-11-6-32(26-50)41(49)24-36/h4-6,9-11,14-18,21,24-25,28,33-34,51H,3,7-8,12-13,19-20,22-23,27,29-30H2,1-2H3,(H,52,58)	VAFCACGNKWELFU-UHFFFAOYSA-N	79966	US20250388575, Compound I-57	Bromodomain-containing protein 4 [353-454]	Homo sapiens			<10						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79966	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79966&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			16656525	252656610							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124173	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2F)c2cc[nH]c2c1=O	InChI=1S/C48H49ClFN7O5/c1-48(2,60)32-8-16-42(37(25-32)38-28-56(3)47(59)45-36(38)18-21-52-45)62-43-15-6-30(24-40(43)50)5-4-29-19-22-57(23-20-29)44-17-14-41(54-55-44)46(58)53-33-9-12-34(13-10-33)61-35-11-7-31(27-51)39(49)26-35/h6-8,11,14-18,21,24-26,28-29,33-34,52,60H,4-5,9-10,12-13,19-20,22-23H2,1-3H3,(H,53,58)	LUJFPGTZCISWTG-UHFFFAOYSA-N	79967	US20250388575, Compound I-111	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 5500						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79967	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79967&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			44601856	252656611							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124174	CCS(=O)(=O)c1ccc(Oc2cc(F)c(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H46ClF2N7O6S/c1-3-64(60,61)34-12-14-42(36(24-34)37-27-56(2)47(59)45-35(37)16-19-52-45)63-43-25-39(49)29(22-40(43)50)5-4-28-17-20-57(21-18-28)44-15-13-41(54-55-44)46(58)53-31-7-10-32(11-8-31)62-33-9-6-30(26-51)38(48)23-33/h6,9,12-16,19,22-25,27-28,31-32,52H,3-5,7-8,10-11,17-18,20-21H2,1-2H3,(H,53,58)	UKVKZGUDRDODLD-UHFFFAOYSA-N	81250	US20250388575, Compound I-59	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81250	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81250&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			386817	252657757							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124175	CCS(=O)(=O)Cc1ccc(Oc2cccc(OC(C)(C)CCC3CCN(c4ncc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C51H56ClN7O7S/c1-5-67(62,63)32-34-9-16-46(43(25-34)44-31-58(4)49(61)47-42(44)18-22-54-47)65-39-7-6-8-41(26-39)66-51(2,3)21-17-33-19-23-59(24-20-33)50-55-29-36(30-56-50)48(60)57-37-11-14-38(15-12-37)64-40-13-10-35(28-53)45(52)27-40/h6-10,13,16,18,22,25-27,29-31,33,37-38,54H,5,11-12,14-15,17,19-21,23-24,32H2,1-4H3,(H,57,60)	JAHPQJHOZHKKGB-UHFFFAOYSA-N	81829	US20250388575, Compound I-154	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81829	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81829&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			23626397	131342403							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124176	CCS(=O)(=O)Nc1ccc(Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H49ClN8O6S/c1-3-63(59,60)54-34-11-18-43(39(26-34)40-29-55(2)47(58)45-38(40)20-23-50-45)62-36-12-6-30(7-13-36)4-5-31-21-24-56(25-22-31)44-19-17-42(52-53-44)46(57)51-33-9-15-35(16-10-33)61-37-14-8-32(28-49)41(48)27-37/h6-8,11-14,17-20,23,26-27,29,31,33,35,50,54H,3-5,9-10,15-16,21-22,24-25H2,1-2H3,(H,51,57)	SKLOAVWFSCZBKK-UHFFFAOYSA-N	81830	US20250388575, Compound I-38	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 550						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81830	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81830&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			23625933	131342404							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124177	Cn1cc(-c2cc(NC(=O)N3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O	InChI=1S/C43H38ClF2N9O5/c1-53-24-33(31-14-15-48-40(31)42(53)57)32-21-28(6-12-37(32)60-38-11-3-26(45)20-35(38)46)50-43(58)55-18-16-54(17-19-55)39-13-10-36(51-52-39)41(56)49-27-4-8-29(9-5-27)59-30-7-2-25(23-47)34(44)22-30/h2-3,6-7,10-15,20-22,24,27,29,48H,4-5,8-9,16-19H2,1H3,(H,49,56)(H,50,58)	JBHHVQTYEUEOPT-UHFFFAOYSA-N	81831	US20250388575, Compound I-218	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81831&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			23626398	131342405							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124178	CCS(=O)(=O)c1ccc(Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)nc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C46H47ClN8O6S/c1-3-62(58,59)36-14-16-42(38(25-36)39-28-54(2)46(57)44-37(39)18-21-49-44)61-35-13-7-31(50-27-35)6-4-29-19-22-55(23-20-29)43-17-15-41(52-53-43)45(56)51-32-8-11-33(12-9-32)60-34-10-5-30(26-48)40(47)24-34/h5,7,10,13-18,21,24-25,27-29,32-33,49H,3-4,6,8-9,11-12,19-20,22-23H2,1-2H3,(H,51,56)	ISEBUFYCCAJXPV-UHFFFAOYSA-N	81832	US20250388575, Compound I-219	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81832	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81832&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			23626552	131342406							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124179	Cn1cc(-c2cc(C(C)(C)O)ccc2OC2CC3(C2)CN(CCC2CCN(c4ncc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC2)C3)c2cc[nH]c2c1=O	InChI=1S/C47H54ClN9O5/c1-46(2,60)31-5-11-41(37(20-31)38-26-55(3)44(59)42-36(38)12-16-50-42)62-35-22-47(23-35)27-56(28-47)17-13-29-14-18-57(19-15-29)45-51-25-40(53-54-45)43(58)52-32-6-9-33(10-7-32)61-34-8-4-30(24-49)39(48)21-34/h4-5,8,11-12,16,20-21,25-26,29,32-33,35,50,60H,6-7,9-10,13-15,17-19,22-23,27-28H2,1-3H3,(H,52,58)	DFZRCFUJEZNTNO-UHFFFAOYSA-N	81833	US20250388575, Compound I-162	Bromodomain-containing protein 4 [353-454]	Homo sapiens			 55						US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81833	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1169&target=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81833&enzyme=Bromodomain-containing+protein+4+%5B353-454%5D&column=ki&startPg=0&Increment=50&submit=Search			23625934	131342407							1	QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF	6C7Q,5UOO,6DUV,8RWZ,8RQ9,7ZNT,7RUH,7JKZ,6SIS,5T35,5JWM,2YEM,2OUO,7OEO,6FFD,8YMB,6MNL,2MJV,2LSP,8IDH,7KO0,4Z93,8G46,8BDX,8BDT,7C6P,5UVZ,5UVY,5UVX,5UVV,5UVU,5UVT,5UVS,5UF0,5UEZ,5UEY,5UEX,5UEV,5UEU,5UET,5UES,5UER,5UEQ,5UEP,5UEO,8RX0,6VIX,5U2C,2I8N,9MPD,6U8I,6U6L,4KV4,8CV6,8CV4,6KO2,7USK,7USJ,7AQT,2DWW,8ZMQ,3JVM,3JVL,8OV6,6DNE	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124180	CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H49ClN8O8S/c1-3-65(59,60)54-32-10-15-43(39(25-32)40-29-55(2)47(58)45-38(40)17-20-50-45)64-36-6-4-5-35(26-36)62-24-23-61-33-18-21-56(22-19-33)44-16-14-42(52-53-44)46(57)51-31-8-12-34(13-9-31)63-37-11-7-30(28-49)41(48)27-37/h4-7,10-11,14-17,20,25-27,29,31,33-34,50,54H,3,8-9,12-13,18-19,21-24H2,1-2H3,(H,51,57)	GSOVRHHVRVFNMZ-UHFFFAOYSA-N	79927	US20250388575, Compound I-1	Progesterone receptor ligand binding domain (LBD)	Homo sapiens	 550								US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79927	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79927&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			22429402	252656571							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124181	CCS(=O)(=O)Cc1ccc(Oc2cccc(OCCOC3CCN(c4cnc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H49ClFN7O8S/c1-3-66(60,61)29-30-7-14-41(37(23-30)38-28-56(2)48(59)46-36(38)15-18-52-46)65-43-6-4-5-42(45(43)50)63-22-21-62-33-16-19-57(20-17-33)44-27-53-40(26-54-44)47(58)55-32-9-12-34(13-10-32)64-35-11-8-31(25-51)39(49)24-35/h4-8,11,14-15,18,23-24,26-28,32-34,52H,3,9-10,12-13,16-17,19-22,29H2,1-2H3,(H,55,58)	YWPUKGUBHRACON-UHFFFAOYSA-N	79934	US20250388575, Compound I-28	Progesterone receptor ligand binding domain (LBD)	Homo sapiens	 550								US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79934	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79934&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			1104012	252656578							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124182	CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H49ClN8O8S/c1-3-65(59,60)54-32-10-15-43(39(25-32)40-29-55(2)47(58)45-38(40)17-20-50-45)64-36-6-4-5-35(26-36)62-24-23-61-33-18-21-56(22-19-33)44-16-14-42(52-53-44)46(57)51-31-8-12-34(13-9-31)63-37-11-7-30(28-49)41(48)27-37/h4-7,10-11,14-17,20,25-27,29,31,33-34,50,54H,3,8-9,12-13,18-19,21-24H2,1-2H3,(H,51,57)	GSOVRHHVRVFNMZ-UHFFFAOYSA-N	79927	US20250388575, Compound I-1	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 550							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79927	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79927&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			22429402	252656571							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124183	CCS(=O)(=O)c1ccc(Oc2cccc(CCCOC3CC4(C3)CN(c3cnc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn3)C4)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C49H49ClFN7O7S/c1-3-66(61,62)36-15-16-42(38(21-36)39-27-57(2)48(60)46-37(39)17-18-53-46)65-43-8-4-6-30(45(43)51)7-5-19-63-35-22-49(23-35)28-58(29-49)44-26-54-41(25-55-44)47(59)56-32-10-13-33(14-11-32)64-34-12-9-31(24-52)40(50)20-34/h4,6,8-9,12,15-18,20-21,25-27,32-33,35,53H,3,5,7,10-11,13-14,19,22-23,28-29H2,1-2H3,(H,56,59)	LYJYLCOMVUSQNK-UHFFFAOYSA-N	81834	US20250388575, Compound I-48	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 5500							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81834&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			23625935	131342408							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124184	Cn1cc(-c2cc(NC(=O)CCCCCCN3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O	InChI=1S/C49H50ClF2N9O5/c1-59-30-39(37-19-20-54-47(37)49(59)64)38-27-34(11-17-43(38)66-44-16-8-32(51)26-41(44)52)55-46(62)6-4-2-3-5-21-60-22-24-61(25-23-60)45-18-15-42(57-58-45)48(63)56-33-9-13-35(14-10-33)65-36-12-7-31(29-53)40(50)28-36/h7-8,11-12,15-20,26-28,30,33,35,54H,2-6,9-10,13-14,21-25H2,1H3,(H,55,62)(H,56,63)	YMJVVXGGSAZFNC-UHFFFAOYSA-N	81835	US20250388575, Compound I-216	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		<10							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81835	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81835&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			23626553	131342409							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124185	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2ccc(CCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2F)c2cc[nH]c2c1=O	InChI=1S/C48H49ClFN7O6/c1-48(2,60)31-6-14-42(37(25-31)38-28-56(3)47(59)45-36(38)16-20-52-45)63-43-13-4-29(24-40(43)50)19-23-61-33-17-21-57(22-18-33)44-15-12-41(54-55-44)46(58)53-32-7-10-34(11-8-32)62-35-9-5-30(27-51)39(49)26-35/h4-6,9,12-16,20,24-26,28,32-34,52,60H,7-8,10-11,17-19,21-23H2,1-3H3,(H,53,58)	NOAHUVIREZJIOX-UHFFFAOYSA-N	81836	US20250388575, Compound I-106	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 55							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81836	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81836&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			54592335	131342410							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124186	CC(C)N(C1CCN(c2ccc(C(=O)N[C@H]3CC[C@H](Oc4ccc(C#N)c(Cl)c4)CC3)nn2)CC1)C1CN(c2cccc(Oc3ccc(C(C)(C)O)cc3-c3cn(C)c(=O)c4[nH]ccc34)c2F)C1	InChI=1S/C52H57ClFN9O5/c1-31(2)63(35-20-23-61(24-21-35)47-18-16-43(58-59-47)50(64)57-34-11-14-37(15-12-34)67-38-13-9-32(27-55)42(53)26-38)36-28-62(29-36)44-7-6-8-46(48(44)54)68-45-17-10-33(52(3,4)66)25-40(45)41-30-60(5)51(65)49-39(41)19-22-56-49/h6-10,13,16-19,22,25-26,30-31,34-37,56,66H,11-12,14-15,20-21,23-24,28-29H2,1-5H3,(H,57,64)	SFULIHDYWRJOKG-UHFFFAOYSA-N	81837	US20250388575, Compound I-141	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 55							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81837	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81837&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			54592336	131342411							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124187	Cn1cc(-c2cc(S(=O)(=O)CCCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O	InChI=1S/C47H46ClF2N7O7S/c1-56-28-38(36-16-19-52-45(36)47(56)59)37-26-35(11-14-42(37)64-43-13-5-30(49)24-40(43)50)65(60,61)23-3-2-22-62-32-17-20-57(21-18-32)44-15-12-41(54-55-44)46(58)53-31-6-9-33(10-7-31)63-34-8-4-29(27-51)39(48)25-34/h4-5,8,11-16,19,24-26,28,31-33,52H,2-3,6-7,9-10,17-18,20-23H2,1H3,(H,53,58)	YMPBTVHKBRRYHU-UHFFFAOYSA-N	79951	US20250388575, Compound I-92	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 55							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79951	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79951&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			4879906	252656595							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124188	CCS(=O)(=O)Cc1ccc(Oc2cccc(CCCCC3CCN(c4ncc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C50H54ClN7O6S/c1-3-65(61,62)32-35-11-18-46(43(26-35)44-31-57(2)49(60)47-42(44)19-22-53-47)64-40-10-6-9-34(25-40)8-5-4-7-33-20-23-58(24-21-33)50-54-29-37(30-55-50)48(59)56-38-13-16-39(17-14-38)63-41-15-12-36(28-52)45(51)27-41/h6,9-12,15,18-19,22,25-27,29-31,33,38-39,53H,3-5,7-8,13-14,16-17,20-21,23-24,32H2,1-2H3,(H,56,59)	ZLZVMUYNIGEFMP-UHFFFAOYSA-N	79937	US20250388575, Compound I-158	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 550							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79937	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79937&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			24817165	252656581							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124189	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2cc(F)c(CCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2F)c2cc[nH]c2c1=O	InChI=1S/C48H48ClF2N7O6/c1-48(2,61)30-5-12-42(36(23-30)37-27-57(3)47(60)45-35(37)14-18-53-45)64-43-25-39(50)28(22-40(43)51)17-21-62-32-15-19-58(20-16-32)44-13-11-41(55-56-44)46(59)54-31-6-9-33(10-7-31)63-34-8-4-29(26-52)38(49)24-34/h4-5,8,11-14,18,22-25,27,31-33,53,61H,6-7,9-10,15-17,19-21H2,1-3H3,(H,54,59)	QNWWFRWQSGTGGL-UHFFFAOYSA-N	81838	US20250388575, Compound I-107	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 55							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81838	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81838&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			54592337	131342412							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124190	CCS(=O)(=O)c1ccc(Oc2ccc(OCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c(-c2ccc(=O)n(C)c2)c1	InChI=1S/C44H45ClN6O7S/c1-3-59(54,55)37-15-17-41(38(25-37)31-5-19-43(52)50(2)27-31)58-35-13-11-33(12-14-35)56-28-29-20-22-51(23-21-29)42-18-16-40(48-49-42)44(53)47-32-6-9-34(10-7-32)57-36-8-4-30(26-46)39(45)24-36/h4-5,8,11-19,24-25,27,29,32,34H,3,6-7,9-10,20-23,28H2,1-2H3,(H,47,53)	OBOXYZNEHWAEJL-UHFFFAOYSA-N	81839	US20250388575, Compound I-235	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 55							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81839	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81839&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			54592338	131342413							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124191	CCS(=O)(=O)c1ccc(Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H47ClFN7O6S/c1-3-63(59,60)35-13-16-42(37(26-35)38-28-55(2)47(58)45-36(38)18-21-51-45)62-43-15-6-30(24-40(43)49)5-4-29-19-22-56(23-20-29)44-17-14-41(53-54-44)46(57)52-32-8-11-33(12-9-32)61-34-10-7-31(27-50)39(48)25-34/h6-7,10,13-18,21,24-26,28-29,32-33,51H,3-5,8-9,11-12,19-20,22-23H2,1-2H3,(H,52,57)	QPVUOKYUAQMCTE-UHFFFAOYSA-N	81840	US20250388575, Compound I-45	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 5500							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81840	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81840&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			23626092	131342414							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124192	CCS(=O)(=O)c1ccc(Oc2cc(F)c(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c(F)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H46ClF2N7O6S/c1-3-64(60,61)34-11-14-43(37(25-34)38-27-56(2)47(59)45-35(38)16-19-52-45)63-33-23-40(49)36(41(50)24-33)12-4-28-17-20-57(21-18-28)44-15-13-42(54-55-44)46(58)53-30-6-9-31(10-7-30)62-32-8-5-29(26-51)39(48)22-32/h5,8,11,13-16,19,22-25,27-28,30-31,52H,3-4,6-7,9-10,12,17-18,20-21H2,1-2H3,(H,53,58)	BVRYINNJYUAKQG-UHFFFAOYSA-N	81841	US20250388575, Compound I-49	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 5500							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81841	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81841&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			23626555	131342415							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124193	CCS(=O)(=O)c1ccc(OCCCCCC2CCN(c3ccc(C(=O)N[C@H]4CC[C@H](Oc5ccc(C#N)c(Cl)c5)CC4)nn3)CC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C44H50ClN7O6S/c1-3-59(55,56)34-14-16-40(36(26-34)37-28-51(2)44(54)42-35(37)18-21-47-42)57-24-6-4-5-7-29-19-22-52(23-20-29)41-17-15-39(49-50-41)43(53)48-31-9-12-32(13-10-31)58-33-11-8-30(27-46)38(45)25-33/h8,11,14-18,21,25-26,28-29,31-32,47H,3-7,9-10,12-13,19-20,22-24H2,1-2H3,(H,48,53)	XIFXBDMZHVQEEB-UHFFFAOYSA-N	79952	US20250388575, Compound I-231	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 5500							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79952	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79952&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			91898290	252656596							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124194	CCS(=O)(=O)c1ccc(Oc2ccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H48ClN7O6S/c1-3-62(58,59)37-16-18-43(39(27-37)40-29-54(2)47(57)45-38(40)20-23-50-45)61-35-11-6-30(7-12-35)4-5-31-21-24-55(25-22-31)44-19-17-42(52-53-44)46(56)51-33-9-14-34(15-10-33)60-36-13-8-32(28-49)41(48)26-36/h6-8,11-13,16-20,23,26-27,29,31,33-34,50H,3-5,9-10,14-15,21-22,24-25H2,1-2H3,(H,51,56)	KLDHUOQEOZOVDJ-UHFFFAOYSA-N	79953	US20250388575, Compound I-50	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 5500							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79953	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79953&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			42600974	252656597							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124195	CCS(=O)(=O)c1ccc(Oc2cccc(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H47ClFN7O6S/c1-3-63(59,60)35-15-17-41(37(26-35)38-28-55(2)47(58)45-36(38)19-22-51-45)62-42-6-4-5-30(44(42)49)8-7-29-20-23-56(24-21-29)43-18-16-40(53-54-43)46(57)52-32-10-13-33(14-11-32)61-34-12-9-31(27-50)39(48)25-34/h4-6,9,12,15-19,22,25-26,28-29,32-33,51H,3,7-8,10-11,13-14,20-21,23-24H2,1-2H3,(H,52,57)	CFNIRKKGKRHUJK-UHFFFAOYSA-N	79954	US20250388575, Compound I-51	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 55							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79954	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79954&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			44142309	252656598							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124196	CCS(=O)(=O)c1ccc(Oc2cccc(CCCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C48H49ClFN7O6S/c1-3-64(60,61)36-16-18-42(38(27-36)39-29-56(2)48(59)46-37(39)20-23-52-46)63-43-9-5-8-31(45(43)50)7-4-6-30-21-24-57(25-22-30)44-19-17-41(54-55-44)47(58)53-33-11-14-34(15-12-33)62-35-13-10-32(28-51)40(49)26-35/h5,8-10,13,16-20,23,26-27,29-30,33-34,52H,3-4,6-7,11-12,14-15,21-22,24-25H2,1-2H3,(H,53,58)	HDYBWMRDCFUMEP-UHFFFAOYSA-N	79956	US20250388575, Compound I-52	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 55							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79956	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79956&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			44142353	252656600							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124197	Cn1cc(-c2cc(NC(=O)CCCCN3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O	InChI=1S/C47H46ClF2N9O5/c1-57-28-37(35-17-18-52-45(35)47(57)62)36-25-32(9-15-41(36)64-42-14-6-30(49)24-39(42)50)53-44(60)4-2-3-19-58-20-22-59(23-21-58)43-16-13-40(55-56-43)46(61)54-31-7-11-33(12-8-31)63-34-10-5-29(27-51)38(48)26-34/h5-6,9-10,13-18,24-26,28,31,33,52H,2-4,7-8,11-12,19-23H2,1H3,(H,53,60)(H,54,61)	AGXOXFLHYZBJEQ-UHFFFAOYSA-N	81842	US20250388575, Compound I-217	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		<10							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81842&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			23626093	131342416							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124198	Cn1cc(-c2cc(C(C)(C)O)ccc2OC2CCC(CCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)C(F)N2F)c2cc[nH]c2c1=O	InChI=1S/C47H53ClF2N8O6/c1-47(2,61)30-6-13-40(36(24-30)37-27-56(3)46(60)43-35(37)16-20-52-43)64-42-15-5-28(44(49)58(42)50)19-23-62-32-17-21-57(22-18-32)41-14-12-39(54-55-41)45(59)53-31-7-10-33(11-8-31)63-34-9-4-29(26-51)38(48)25-34/h4,6,9,12-14,16,20,24-25,27-28,31-33,42,44,52,61H,5,7-8,10-11,15,17-19,21-23H2,1-3H3,(H,53,59)	KKPMLBUAUOQRTE-UHFFFAOYSA-N	79957	US20250388575, Compound I-108	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 55							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79957	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79957&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			44142359	252656601							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124199	Cn1cc(-c2cc(C(C)(C)O)ccc2Oc2c(F)cc(CCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2F)c2cc[nH]c2c1=O	InChI=1S/C48H48ClF2N7O6/c1-48(2,61)30-5-12-42(36(24-30)37-27-57(3)47(60)44-35(37)14-18-53-44)64-45-39(50)22-28(23-40(45)51)17-21-62-32-15-19-58(20-16-32)43-13-11-41(55-56-43)46(59)54-31-6-9-33(10-7-31)63-34-8-4-29(26-52)38(49)25-34/h4-5,8,11-14,18,22-25,27,31-33,53,61H,6-7,9-10,15-17,19-21H2,1-3H3,(H,54,59)	MZUGIDOHZCAPFV-UHFFFAOYSA-N	79958	US20250388575, Compound I-109	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 55							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79958	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79958&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			44142494	252656602							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124200	CCS(=O)(=O)c1ccc(Oc2ccc(N3CC4(CCN(c5ccc(C(=O)N[C@H]6CC[C@H](Oc7ccc(C#N)c(Cl)c7)CC6)nn5)CC4)C3)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H47ClN8O6S/c1-3-63(59,60)36-14-16-42(38(25-36)39-27-54(2)46(58)44-37(39)18-21-50-44)62-34-12-7-32(8-13-34)56-28-47(29-56)19-22-55(23-20-47)43-17-15-41(52-53-43)45(57)51-31-5-10-33(11-6-31)61-35-9-4-30(26-49)40(48)24-35/h4,7-9,12-18,21,24-25,27,31,33,50H,3,5-6,10-11,19-20,22-23,28-29H2,1-2H3,(H,51,57)	SUYILVBAYAQMKD-UHFFFAOYSA-N	79959	US20250388575, Compound I-90	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 5500							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79959	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79959&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			44144121	252656603							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124201	Cn1cc(-c2cc(S(=O)(=O)CCCCCN3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O	InChI=1S/C47H47ClF2N8O6S/c1-56-29-38(36-17-18-52-45(36)47(56)60)37-27-35(12-15-42(37)64-43-14-6-31(49)25-40(43)50)65(61,62)24-4-2-3-19-57-20-22-58(23-21-57)44-16-13-41(54-55-44)46(59)53-32-7-10-33(11-8-32)63-34-9-5-30(28-51)39(48)26-34/h5-6,9,12-18,25-27,29,32-33,52H,2-4,7-8,10-11,19-24H2,1H3,(H,53,59)	UHRJYRIMFWUQPW-UHFFFAOYSA-N	81843	US20250388575, Compound I-94	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 55							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81843	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81843&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			23626556	131342417							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124202	Cn1cc(-c2cc(C(C)(C)O)ccc2O[C@H]2C[C@H](N(C)CC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)C2)c2cc[nH]c2c1=O	InChI=1S/C46H53ClN8O5/c1-46(2,58)30-6-13-41(37(21-30)38-27-54(4)45(57)43-36(38)15-18-49-43)60-35-22-32(23-35)53(3)26-28-16-19-55(20-17-28)42-14-12-40(51-52-42)44(56)50-31-7-10-33(11-8-31)59-34-9-5-29(25-48)39(47)24-34/h5-6,9,12-15,18,21,24,27-28,31-33,35,49,58H,7-8,10-11,16-17,19-20,22-23,26H2,1-4H3,(H,50,56)	MMYWAFRFETZYMF-UHFFFAOYSA-N	81844	US20250388575, Compound I-159	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 5500							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81844	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81844&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			23626094	131342418							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
124203	CCS(=O)(=O)c1ccc(Oc2cc(F)c(CCC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)cc2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1	InChI=1S/C47H46ClF2N7O6S/c1-3-64(60,61)34-12-14-42(36(24-34)37-27-56(2)47(59)45-35(37)16-19-52-45)63-43-25-39(49)29(22-40(43)50)5-4-28-17-20-57(21-18-28)44-15-13-41(54-55-44)46(58)53-31-7-10-32(11-8-31)62-33-9-6-30(26-51)38(48)23-33/h6,9,12-16,19,22-25,27-28,31-32,52H,3-5,7-8,10-11,17-18,20-21H2,1-2H3,(H,53,58)	UKVKZGUDRDODLD-UHFFFAOYSA-N	81250	US20250388575, Compound I-59	Progesterone receptor ligand binding domain (LBD)	Homo sapiens		 5500							US Patent		10.7270/Q2GM8D3H			US20250388575	Eastman, KJ; Kayser-Bricker, K; Mousseau, JJ; Neklesa, T; Puleo, DE; Raina, KS; Zaware, N; Gerritz, S; Bosanac, T	12/25/2025	5/6/2026	Halda Therapeutics OpCo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81250	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6757&target=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81250&enzyme=Progesterone+receptor+ligand+binding+domain+%28LBD%29&column=ki&startPg=0&Increment=50&submit=Search			386817	252657757							1	MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK	1SQN,3G8O,4APU,4A2J,3ZRB,3ZRA,3ZR7,2W8Y,3HQ5,3D90,2OVM,2OVH,1ZUC,1SR7,1E3K,1A28,4OAR,3KBA,2C7A	Progesterone receptor	PRGR_HUMAN	P06401	A7LQ08 A7X8B0 B4E3T0 Q8TDS3 Q9UPF7