BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
125249	CC(C)(C)OC(=O)NCc1cn(C2CCCCNC2=O)nn1	InChI=1S/C14H23N5O3/c1-14(2,3)22-13(21)16-8-10-9-19(18-17-10)11-6-4-5-7-15-12(11)20/h9,11H,4-8H2,1-3H3,(H,15,20)(H,16,21)	JTHUUBDVROYBNW-UHFFFAOYSA-N	87350	tert-Butyl N-[[1-(2-oxoazepan-3-yl)triazol-4-yl]methyl]carbamate::US20250388593, Example 1	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87350&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2724387	252659782							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125250	CC(C)(C)OC(=O)N1CCC(c2cn(C3CCCC(=O)NC3=O)nn2)CC1	InChI=1S/C18H27N5O4/c1-18(2,3)27-17(26)22-9-7-12(8-10-22)13-11-23(21-20-13)14-5-4-6-15(24)19-16(14)25/h11-12,14H,4-10H2,1-3H3,(H,19,24,25)	SINYDHDOMXWBAQ-UHFFFAOYSA-N	87352	US20250388593, Example 2	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87352	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87352&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			8271970	252659784							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125251	CC(C)(C)OC(=O)Nc1ccc(-c2cn(C3CCCC(=O)NC3=O)nn2)cc1	InChI=1S/C19H23N5O4/c1-19(2,3)28-18(27)20-13-9-7-12(8-10-13)14-11-24(23-22-14)15-5-4-6-16(25)21-17(15)26/h7-11,15H,4-6H2,1-3H3,(H,20,27)(H,21,25,26)	SRHUMUVTJMKTDN-UHFFFAOYSA-N	87353	US20250388593, Example 3	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87353	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87353&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4849353	252659785							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125252	CC(C)(C)OC(=O)Nc3cccc(c2cn(C1CCCC(=O)NC1=O)nn2)c3	InChI=1S/C19H23N5O4/c1-19(2,3)28-18(27)20-13-7-4-6-12(10-13)14-11-24(23-22-14)15-8-5-9-16(25)21-17(15)26/h4,6-7,10-11,15H,5,8-9H2,1-3H3,(H,20,27)(H,21,25,26)	LMUHRNXTIQRZNM-UHFFFAOYSA-N	87354	tert-Butyl N-[3-[1-(2-oxoazepan-3-yl) triazol-4-yl]phenyl]carbamate::US20250388593, Example 5	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87354	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87354&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			17757075	252659786							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125253	CC(C)(C)OC(=O)Nc1ccccc1-c1cn(C2CCCC(=O)NC2=O)nn1	InChI=1S/C19H23N5O4/c1-19(2,3)28-18(27)20-13-8-5-4-7-12(13)14-11-24(23-22-14)15-9-6-10-16(25)21-17(15)26/h4-5,7-8,11,15H,6,9-10H2,1-3H3,(H,20,27)(H,21,25,26)	WTDOTEMLYSBESC-UHFFFAOYSA-N	87355	US20250388593, Example 6	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87355	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87355&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2397406	252659787							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125254	CN(C1CCCC(=O)NC1=O)S(=O)(=O)c1ccc(Cl)cc1	InChI=1S/C13H15ClN2O4S/c1-16(11-3-2-4-12(17)15-13(11)18)21(19,20)10-7-5-9(14)6-8-10/h5-8,11H,2-4H2,1H3,(H,15,17,18)	JSNFSKNNQYWNBK-UHFFFAOYSA-N	87356	4-Chloro-N-(2,7-dioxoazepan-3-yl)-N-methylbenzenesulfonamide::US20250388593, Example 7	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87356	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87356&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2626966	252659788							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125255	O=C1CCCC(NS(=O)(=O)c2ccc(Cl)cc2)C(=O)N1	InChI=1S/C12H13ClN2O4S/c13-8-4-6-9(7-5-8)20(18,19)15-10-2-1-3-11(16)14-12(10)17/h4-7,10,15H,1-3H2,(H,14,16,17)	CLCASNZGTALWCD-UHFFFAOYSA-N	87357	US20250388593, Example 8	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87357	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87357&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6540194	252659789							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125256	O=C1CCCC(NS(=O)(=O)c2cccc(Cl)c2)C(=O)N1	InChI=1S/C12H13ClN2O4S/c13-8-3-1-4-9(7-8)20(18,19)15-10-5-2-6-11(16)14-12(10)17/h1,3-4,7,10,15H,2,5-6H2,(H,14,16,17)	ZOKQAEBEMBRNON-UHFFFAOYSA-N	87358	US20250388593, Example 9	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87358	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87358&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			44602021	252659790							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125257	CN(C1CCCC(=O)NC1=O)S(=O)(=O)c1cccc(Cl)c1	InChI=1S/C13H15ClN2O4S/c1-16(11-6-3-7-12(17)15-13(11)18)21(19,20)10-5-2-4-9(14)8-10/h2,4-5,8,11H,3,6-7H2,1H3,(H,15,17,18)	HMHDHJTXLTYBIU-UHFFFAOYSA-N	87359	US20250388593, Example 10	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87359	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87359&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			230794	252659791							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125258	COC(=O)c1cccc(S(=O)(=O)N(C)C2CCCC(=O)NC2=O)c1	InChI=1S/C15H18N2O6S/c1-17(12-7-4-8-13(18)16-14(12)19)24(21,22)11-6-3-5-10(9-11)15(20)23-2/h3,5-6,9,12H,4,7-8H2,1-2H3,(H,16,18,19)	VPEFFVLUSINTQQ-UHFFFAOYSA-N	87366	US20250388593, Example 11	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87366	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87366&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			313582	252659794							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125259	O=C3COCC2(CCCN(C(=O)c1ccccc1)C2)C(=O)N3	InChI=1S/C16H18N2O4/c19-13-9-22-11-16(15(21)17-13)7-4-8-18(10-16)14(20)12-5-2-1-3-6-12/h1-3,5-6H,4,7-11H2,(H,17,19,21)	PPWYBVBINJEZJC-UHFFFAOYSA-N	87378	US20250388593, Example 12-2	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87378	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87378&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			9571612	252659796							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125260	O=C1COCC2(CCN(C(=O)c3ccccc3)CC2)C(=O)N1	InChI=1S/C16H18N2O4/c19-13-10-22-11-16(15(21)17-13)6-8-18(9-7-16)14(20)12-4-2-1-3-5-12/h1-5H,6-11H2,(H,17,19,21)	UBJHUEOUEQTQBA-UHFFFAOYSA-N	87534	US20250388593, Example 13-2	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87534	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87534&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46942891	252659939							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125261	O=C1CCCC2(CCCN(C(=O)c3ccccc3)CCC2)C(=O)N1	InChI=1S/C19H24N2O3/c22-16-9-4-10-19(18(24)20-16)11-5-13-21(14-6-12-19)17(23)15-7-2-1-3-8-15/h1-3,7-8H,4-6,9-14H2,(H,20,22,24)	ZMIHTNLXCUCFRO-UHFFFAOYSA-N	87547	US20250388593, Example 14	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87547	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87547&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			51360334	252659940							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125262	CC(C)(C)OC(=O)c1ccc(N2CCCC3(COCC(=O)NC3=O)C2)nc1	InChI=1S/C19H25N3O5/c1-18(2,3)27-16(24)13-5-6-14(20-9-13)22-8-4-7-19(11-22)12-26-10-15(23)21-17(19)25/h5-6,9H,4,7-8,10-12H2,1-3H3,(H,21,23,25)	PBIOMTMVRLQQQM-UHFFFAOYSA-N	87583	US20250388593, Example 15	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87583	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87583&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			702724	252659959							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125263	CC(C)(C)OC(=O)c1ccc(N2CCC3(CC2)COCC(=O)NC3=O)nc1	InChI=1S/C19H25N3O5/c1-18(2,3)27-16(24)13-4-5-14(20-10-13)22-8-6-19(7-9-22)12-26-11-15(23)21-17(19)25/h4-5,10H,6-9,11-12H2,1-3H3,(H,21,23,25)	AVZRIRMKPHAQIJ-UHFFFAOYSA-N	87584	US20250388593, Example 16	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87584	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87584&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5300120	252659960							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125264	O=C1CCOC(c2ccccc2)C(=O)N1	InChI=1S/C11H11NO3/c13-9-6-7-15-10(11(14)12-9)8-4-2-1-3-5-8/h1-5,10H,6-7H2,(H,12,13,14)	RAUIOQJWYAKXEH-UHFFFAOYSA-N	87585	2-Phenyl-1,4-oxazepane-3,5-dione::US20250388593, Example 18	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87585	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87585&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5300283	252659961							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125265	O=C1CCOC(c2cccc(Br)c2)C(=O)N1	InChI=1S/C11H10BrNO3/c12-8-3-1-2-7(6-8)10-11(15)13-9(14)4-5-16-10/h1-3,6,10H,4-5H2,(H,13,14,15)	ZSQUSQBSLNEZEU-UHFFFAOYSA-N	87586	US20250388593, Example 19	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87586	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87586&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			915026	252659962							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125266	CN(C(=O)c1cccc(-c2ccccc2)c1)C1CCCC(=O)NC1=O	InChI=1S/C20H20N2O3/c1-22(17-11-6-12-18(23)21-19(17)24)20(25)16-10-5-9-15(13-16)14-7-3-2-4-8-14/h2-5,7-10,13,17H,6,11-12H2,1H3,(H,21,23,24)	UBCDKBQAKZURGK-UHFFFAOYSA-N	87587	N-(2,7-Dioxoazepan-3-yl)-N-methyl-3-phenylbenzamide::US20250388593, Example 20	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87587	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87587&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3155792	252659963							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125267	O=C1CCCC(NC(=O)c2cccc(-c3ccccc3)c2)C(=O)N1	InChI=1S/C19H18N2O3/c22-17-11-5-10-16(19(24)21-17)20-18(23)15-9-4-8-14(12-15)13-6-2-1-3-7-13/h1-4,6-9,12,16H,5,10-11H2,(H,20,23)(H,21,22,24)	VYADTGLHVIWDDH-UHFFFAOYSA-N	87588	US20250388593, Example 21	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87588	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87588&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5401892	252659964							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125268	O=C1COCC(NC(=O)c2cccc(-c3ccccc3)c2)C(=O)N1	InChI=1S/C18H16N2O4/c21-16-11-24-10-15(18(23)20-16)19-17(22)14-8-4-7-13(9-14)12-5-2-1-3-6-12/h1-9,15H,10-11H2,(H,19,22)(H,20,21,23)	LTWKQGDWUQVGTI-UHFFFAOYSA-N	87783	US20250388593, Example 22	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87783	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87783&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1442514	252660082							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125269	CC(C)(C)OC(=O)N(CC1CCCC(=O)NC1=O)c1ccc(F)cc1	InChI=1S/C18H23FN2O4/c1-18(2,3)25-17(24)21(14-9-7-13(19)8-10-14)11-12-5-4-6-15(22)20-16(12)23/h7-10,12H,4-6,11H2,1-3H3,(H,20,22,23)	OOJFEDUEFZNJJK-UHFFFAOYSA-N	87827	tert-Butyl N-[(2,7-dioxoazepan-3-yl) methyl]-N-(4-fluorophenyl) carbamate::US20250388593, Example 24	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87827	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87827&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1349228	252660090							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125270	O=C1CCCC(CNc2ccc(F)cc2)C(=O)N1	InChI=1S/C13H15FN2O2/c14-10-4-6-11(7-5-10)15-8-9-2-1-3-12(17)16-13(9)18/h4-7,9,15H,1-3,8H2,(H,16,17,18)	XURSAOXRJFOVIH-UHFFFAOYSA-N	87901	US20250388593, Example 25	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87901	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87901&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3857241	252660099							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125271	COC(=O)c1ccc(=O)n(C2CCCC(=O)NC2=O)c1	InChI=1S/C13H14N2O5/c1-20-13(19)8-5-6-11(17)15(7-8)9-3-2-4-10(16)14-12(9)18/h5-7,9H,2-4H2,1H3,(H,14,16,18)	GSOVSYLAMXWEGC-UHFFFAOYSA-N	88420	Methyl 1-(2,7-dioxoazepan-3-yl)-6-oxopyridine-3-carboxylate ::US20250388593, Example 26	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88420	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88420&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			9568667	252660136							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125272	CN(C1CCCC(=O)NC1=O)S(=O)(=O)c1ccc(CNC(=O)OC(C)(C)C)cc1	InChI=1S/C19H27N3O6S/c1-19(2,3)28-18(25)20-12-13-8-10-14(11-9-13)29(26,27)22(4)15-6-5-7-16(23)21-17(15)24/h8-11,15H,5-7,12H2,1-4H3,(H,20,25)(H,21,23,24)	HAYAKFYYLSIEQZ-UHFFFAOYSA-N	88421	US20250388593, Example 27	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88421	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88421&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2944700	252660137							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125273	O=C1CCCC(C(=O)Nc2ccc(F)cc2)C(=O)N1	InChI=1S/C13H13FN2O3/c14-8-4-6-9(7-5-8)15-12(18)10-2-1-3-11(17)16-13(10)19/h4-7,10H,1-3H2,(H,15,18)(H,16,17,19)	RBUNOWIRWQSQPG-UHFFFAOYSA-N	88422	N-(4-Fluorophenyl)-2,7-dioxoazepane-3-carboxamide::US20250388593, Example 28	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88422	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88422&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1247777	252660138							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125274	CC(C)(C)OC(=O)N2CCN(C1CCCC(=O)NC1=O)C(=O)C2	InChI=1S/C15H23N3O5/c1-15(2,3)23-14(22)17-7-8-18(12(20)9-17)10-5-4-6-11(19)16-13(10)21/h10H,4-9H2,1-3H3,(H,16,19,21)	ZABLNDADWWWQNM-UHFFFAOYSA-N	88423	 tert-Butyl N-[2-[(2-oxoazepan-3-yl)amino]ethyl]carbamate ::US20250388593, Example 29-1	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88423	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88423&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5307804	252660139							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125275	CC(C)(C)OC(=O)N1CCN(C2CCCC(=O)NC2=O)C(=O)C1=O	InChI=1S/C15H21N3O6/c1-15(2,3)24-14(23)18-8-7-17(12(21)13(18)22)9-5-4-6-10(19)16-11(9)20/h9H,4-8H2,1-3H3,(H,16,19,20)	CCJAJCYAJOCWBI-UHFFFAOYSA-N	88424	tert-Butyl 4-(2,7-dioxoazepan-3-yl)-2,3-dioxopiperazine-1-carboxylate ::US20250388593, Example 29-2	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88424	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88424&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			9549133	252660140							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125276	CC(C)(C)OC(=O)c1ccc(N2CCN(C3CCCC(=O)NC3=O)C(=O)C2)nc1	InChI=1S/C20H26N4O5/c1-20(2,3)29-19(28)13-7-8-15(21-11-13)23-9-10-24(17(26)12-23)14-5-4-6-16(25)22-18(14)27/h7-8,11,14H,4-6,9-10,12H2,1-3H3,(H,22,25,27)	HBWUNVQSBLANPU-UHFFFAOYSA-N	88425	US20250388593, Example 30	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88425	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88425&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			9550523	252660141							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125277	CC1(CN2C(=O)c3ccccc3C2=O)CCCC(=O)NC1=O	InChI=1S/C16H16N2O4/c1-16(8-4-7-12(19)17-15(16)22)9-18-13(20)10-5-2-3-6-11(10)14(18)21/h2-3,5-6H,4,7-9H2,1H3,(H,17,19,22)	PDFYDUPFAZOCQO-UHFFFAOYSA-N	88426	2-[(3-Methyl-2,7-dioxoazepan-3-yl) methyl]isoindole-1,3-dione::US20250388593, Example 31	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88426	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88426&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5070905	252660142							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125278	CC(C)(C)OC(=O)c1cnc(N2CCC3(CCCC(=O)NC3=O)C2)nc1	InChI=1S/C18H24N4O4/c1-17(2,3)26-14(24)12-9-19-16(20-10-12)22-8-7-18(11-22)6-4-5-13(23)21-15(18)25/h9-10H,4-8,11H2,1-3H3,(H,21,23,25)	DNXVQYIGMXPSQK-UHFFFAOYSA-N	88427	US20250388593, Example 32	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88427	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88427&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1292146	252660143							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125279	COC(=O)c1cccc(CN2CCC3(CCCC(=O)NC3=O)C2)c1	InChI=1S/C18H22N2O4/c1-24-16(22)14-5-2-4-13(10-14)11-20-9-8-18(12-20)7-3-6-15(21)19-17(18)23/h2,4-5,10H,3,6-9,11-12H2,1H3,(H,19,21,23)	DYFQLLSIBBPDIP-UHFFFAOYSA-N	88428	US20250388593, Example 33	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88428	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88428&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			9551548	252660144							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125280	COC(=O)c1ccc(CN2CCC3(CCCC(=O)NC3=O)C2)cc1	InChI=1S/C18H22N2O4/c1-24-16(22)14-6-4-13(5-7-14)11-20-10-9-18(12-20)8-2-3-15(21)19-17(18)23/h4-7H,2-3,8-12H2,1H3,(H,19,21,23)	MNWPSJMUHQKEHY-UHFFFAOYSA-N	88429	US20250388593, Example 34	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88429	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88429&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6878737	252660145							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125281	CC(C)(C)OC(=O)c1cnc(N2CCC3(CCCC(=O)NC3=O)C2)cn1	InChI=1S/C18H24N4O4/c1-17(2,3)26-15(24)12-9-20-13(10-19-12)22-8-7-18(11-22)6-4-5-14(23)21-16(18)25/h9-10H,4-8,11H2,1-3H3,(H,21,23,25)	DXYUTFOYFKJUIC-UHFFFAOYSA-N	88430	US20250388593, Example 35	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88430	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88430&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2895599	252660146							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125282	COC(=O)c1cc2c(N3CCC4(CCCC(=O)NC4=O)C3)ncnc2n1C	InChI=1S/C18H21N5O4/c1-22-12(16(25)27-2)8-11-14(22)19-10-20-15(11)23-7-6-18(9-23)5-3-4-13(24)21-17(18)26/h8,10H,3-7,9H2,1-2H3,(H,21,24,26)	NMPJJRMGUQDRAK-UHFFFAOYSA-N	88431	US20250388593, Example 36	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88431	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88431&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			91899114	252660147							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125283	Cn1ccc2c(N3CCC4(CCCC(=O)NC4=O)C3)ncnc21	InChI=1S/C16H19N5O2/c1-20-7-4-11-13(20)17-10-18-14(11)21-8-6-16(9-21)5-2-3-12(22)19-15(16)23/h4,7,10H,2-3,5-6,8-9H2,1H3,(H,19,22,23)	MOWVDODWZGOFJH-UHFFFAOYSA-N	88432	US20250388593, Example 37	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88432	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88432&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6260079	252660148							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125284	O=C1CCCC2(CCN(c3ccc(C(F)(F)F)cn3)C2)C(=O)N1	InChI=1S/C15H16F3N3O2/c16-15(17,18)10-3-4-11(19-8-10)21-7-6-14(9-21)5-1-2-12(22)20-13(14)23/h3-4,8H,1-2,5-7,9H2,(H,20,22,23)	YPRSNYPXPJFGFN-UHFFFAOYSA-N	88433	US20250388593, Example 38	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88433	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88433&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5765807	252660149							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125285	Cn1ncc2c(N3CCC4(CCCC(=O)NC4=O)C3)ncnc21	InChI=1S/C15H18N6O2/c1-20-12-10(7-18-20)13(17-9-16-12)21-6-5-15(8-21)4-2-3-11(22)19-14(15)23/h7,9H,2-6,8H2,1H3,(H,19,22,23)	QAILTKHLCMSDPO-UHFFFAOYSA-N	88434	US20250388593, Example 39	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88434	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88434&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3365190	252660150							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125286	CCOC(=O)c1cc(N2CCC3(CCCC(=O)NC3=O)C2)ncc1C(F)(F)F	InChI=1S/C18H20F3N3O4/c1-2-28-15(26)11-8-13(22-9-12(11)18(19,20)21)24-7-6-17(10-24)5-3-4-14(25)23-16(17)27/h8-9H,2-7,10H2,1H3,(H,23,25,27)	YIRVZODSOGADHX-UHFFFAOYSA-N	88435	US20250388593, Example 40	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88435	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88435&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1474409	252660151							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125287	COc3cc(N2CCC1(CCCC(=O)NC1=O)C2)ccc3[N+](=O)[O-]	InChI=1S/C16H19N3O5/c1-24-13-9-11(4-5-12(13)19(22)23)18-8-7-16(10-18)6-2-3-14(20)17-15(16)21/h4-5,9H,2-3,6-8,10H2,1H3,(H,17,20,21)	ZMJDVZCYILVPEX-UHFFFAOYSA-N	88436	US20250388593, Example 41	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88436	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88436&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1224409	252660152							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125288	COc1cc([N+](=O)[O-])ccc1N3CCC2(CCCC(=O)NC2=O)C3	InChI=1S/C16H19N3O5/c1-24-13-9-11(19(22)23)4-5-12(13)18-8-7-16(10-18)6-2-3-14(20)17-15(16)21/h4-5,9H,2-3,6-8,10H2,1H3,(H,17,20,21)	ZNVIZRYGDWLCOB-UHFFFAOYSA-N	88437	US20250388593, Example 42	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88437	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88437&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1090028	252660153							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125289	COC(=O)c1cc2ncnc(N3CCC4(CCCC(=O)NC4=O)C3)c2s1	InChI=1S/C17H18N4O4S/c1-25-15(23)11-7-10-13(26-11)14(19-9-18-10)21-6-5-17(8-21)4-2-3-12(22)20-16(17)24/h7,9H,2-6,8H2,1H3,(H,20,22,24)	KUJTZKMAFZBHOW-UHFFFAOYSA-N	88438	US20250388593, Example 43	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88438	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88438&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1073607	252660154							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125290	CC(C)(C)OC(=O)N1CC2(CC(=O)N(C3CCC(=O)NC3=O)C2=O)C1	InChI=1S/C16H21N3O6/c1-15(2,3)25-14(24)18-7-16(8-18)6-11(21)19(13(16)23)9-4-5-10(20)17-12(9)22/h9H,4-8H2,1-3H3,(H,17,20,22)	OXOURRNLCMQWQB-UHFFFAOYSA-N	88439	US20250388593, Example 44-2	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88439	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88439&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1048268	252660155							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125291	CC(C)(C)OC(=O)c1ccc(N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)nc1	InChI=1S/C21H24N4O6/c1-20(2,3)31-18(29)12-4-6-14(22-9-12)24-10-21(11-24)8-16(27)25(19(21)30)13-5-7-15(26)23-17(13)28/h4,6,9,13H,5,7-8,10-11H2,1-3H3,(H,23,26,28)	FRTFKWJYECPXBY-UHFFFAOYSA-N	88440	US20250388593, Example 45	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88440	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88440&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6241538	252660156							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125292	CC(C)(C)OC(=O)c1ccnc(N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)c1	InChI=1S/C21H24N4O6/c1-20(2,3)31-18(29)12-6-7-22-14(8-12)24-10-21(11-24)9-16(27)25(19(21)30)13-4-5-15(26)23-17(13)28/h6-8,13H,4-5,9-11H2,1-3H3,(H,23,26,28)	SULFHTOAGBDWIL-UHFFFAOYSA-N	88441	US20250388593, Example 46	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88441	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88441&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1873833	252660157							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125293	CC(C)(C)OC(=O)c1cccc(N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)n1	InChI=1S/C21H24N4O6/c1-20(2,3)31-18(29)12-5-4-6-14(22-12)24-10-21(11-24)9-16(27)25(19(21)30)13-7-8-15(26)23-17(13)28/h4-6,13H,7-11H2,1-3H3,(H,23,26,28)	HZTYMIVXMUBJET-UHFFFAOYSA-N	88442	US20250388593, Example 47	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88442	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88442&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1349192	252660158							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125294	CC(C)(C)OC(=O)CN1CC2(CC(=O)N(C3CCC(=O)NC3=O)C2=O)C1	InChI=1S/C17H23N3O6/c1-16(2,3)26-13(23)7-19-8-17(9-19)6-12(22)20(15(17)25)10-4-5-11(21)18-14(10)24/h10H,4-9H2,1-3H3,(H,18,21,24)	ZDRPNMFIRFZUQY-UHFFFAOYSA-N	88443	US20250388593, Example 48	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88443	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88443&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2957625	252660159							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125295	CC(C)(C)OC(=O)C(C)(C)N1CC2(CC(=O)N(C3CCC(=O)NC3=O)C2=O)C1	InChI=1S/C19H27N3O6/c1-17(2,3)28-16(27)18(4,5)21-9-19(10-21)8-13(24)22(15(19)26)11-6-7-12(23)20-14(11)25/h11H,6-10H2,1-5H3,(H,20,23,25)	PFSXIMHJHKHFFU-UHFFFAOYSA-N	88444	US20250388593, Example 49	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88444&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5739567	252660160							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125296	CC(C)(C)OC(=O)NCCCCCN1CC2(CC(=O)N(C3CCC(=O)NC3=O)C2=O)C1	InChI=1S/C21H32N4O6/c1-20(2,3)31-19(30)22-9-5-4-6-10-24-12-21(13-24)11-16(27)25(18(21)29)14-7-8-15(26)23-17(14)28/h14H,4-13H2,1-3H3,(H,22,30)(H,23,26,28)	RDEAWYQJHDBFLW-UHFFFAOYSA-N	88445	US20250388593, Example 50	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88445&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1865512	252660161							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125297	CC(C)(C)OC(=O)NCCCCCCCCN1CC2(CC(=O)N(C3CCC(=O)NC3=O)C2=O)C1	InChI=1S/C24H38N4O6/c1-23(2,3)34-22(33)25-12-8-6-4-5-7-9-13-27-15-24(16-27)14-19(30)28(21(24)32)17-10-11-18(29)26-20(17)31/h17H,4-16H2,1-3H3,(H,25,33)(H,26,29,31)	PZHCAYMCMMCGHJ-UHFFFAOYSA-N	88446	US20250388593, Example 51	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88446&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			91899115	252660162							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125298	CCOC(=O)c1ccc2nc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)sc2c1	InChI=1S/C21H20N4O6S/c1-2-31-18(29)11-3-4-12-14(7-11)32-20(22-12)24-9-21(10-24)8-16(27)25(19(21)30)13-5-6-15(26)23-17(13)28/h3-4,7,13H,2,5-6,8-10H2,1H3,(H,23,26,28)	KZZMPTKFLPFXHY-UHFFFAOYSA-N	88447	US20250388593, Example 52	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88447&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1132167	252660163							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125299	COC(=O)c1cccc(CN2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)c1	InChI=1S/C20H21N3O6/c1-29-18(27)13-4-2-3-12(7-13)9-22-10-20(11-22)8-16(25)23(19(20)28)14-5-6-15(24)21-17(14)26/h2-4,7,14H,5-6,8-11H2,1H3,(H,21,24,26)	FLMFIHUDVLUOAR-UHFFFAOYSA-N	88448	US20250388593, Example 53	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88448&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3145758	252660164							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125300	COC(=O)c1ccc(CN2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)cc1	InChI=1S/C20H21N3O6/c1-29-18(27)13-4-2-12(3-5-13)9-22-10-20(11-22)8-16(25)23(19(20)28)14-6-7-15(24)21-17(14)26/h2-5,14H,6-11H2,1H3,(H,21,24,26)	JKKSSIXFCXQERZ-UHFFFAOYSA-N	88449	US20250388593, Example 54	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88449&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			631552	252660165							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125301	O=C1CCC(N2C(=O)CC3(CN(C(=O)CNC(=O)c4ccccc4)C3)C2=O)C(=O)N1	InChI=1S/C20H20N4O6/c25-14-7-6-13(18(29)22-14)24-15(26)8-20(19(24)30)10-23(11-20)16(27)9-21-17(28)12-4-2-1-3-5-12/h1-5,13H,6-11H2,(H,21,28)(H,22,25,29)	VWYDPAXUGXKNIS-UHFFFAOYSA-N	88450	US20250388593, Example 55	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88450	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88450&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4271672	252660166							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125302	CC(C)(C)OC(=O)c1ccc(N2CCCC3(CCCC(=O)NC3=O)CCC2)nc1	InChI=1S/C22H31N3O4/c1-21(2,3)29-19(27)16-8-9-17(23-15-16)25-13-5-11-22(12-6-14-25)10-4-7-18(26)24-20(22)28/h8-9,15H,4-7,10-14H2,1-3H3,(H,24,26,28)	ORFOUNMQGLWBNX-UHFFFAOYSA-N	88452	tert-Butyl 6-(1,3-dioxo-2,11-diazaspiro [6.7]tetradecan-11-yl) pyridine-3-carboxylate::US20250388593, Example 56	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88452	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88452&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			12006041	252660168							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125303	O=C1CCCC(CNC(=O)c2ccccc2)C(=O)N1	InChI=1S/C14H16N2O3/c17-12-8-4-7-11(14(19)16-12)9-15-13(18)10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,15,18)(H,16,17,19)	LBIOXQODMKOGTQ-UHFFFAOYSA-N	88454	N-[(2,7-Dioxoazepan-3-yl) methyl]benzamide::US20250388593, Example 57	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88454	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88454&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2102682	252660170							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125304	CCOC(=O)c1ccc2nc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)sc2c1	InChI=1S/C21H20N4O6S/c1-2-31-18(29)11-3-4-12-14(7-11)32-20(22-12)24-9-21(10-24)8-16(27)25(19(21)30)13-5-6-15(26)23-17(13)28/h3-4,7,13H,2,5-6,8-10H2,1H3,(H,23,26,28)	KZZMPTKFLPFXHY-UHFFFAOYSA-N	88455	US20250388593, Example 59	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88455	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88455&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			91899116	252660171							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125305	CC(C)(C)OC(=O)C1=CC(C2CCCC(=O)NC2=O)CC=C1	InChI=1S/C17H23NO4/c1-17(2,3)22-16(21)12-7-4-6-11(10-12)13-8-5-9-14(19)18-15(13)20/h4,7,10-11,13H,5-6,8-9H2,1-3H3,(H,18,19,20)	ZVOVMWPGRSVFIB-UHFFFAOYSA-N	88456	tert-Butyl 3-(2,7-dioxoazepan-3-yl) benzoate::US20250388593, Example 60	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88456	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88456&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6899633	252660172							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125306	O=C1CCCC(c2ccc([N+](=O)[O-])cc2)C(=O)N1	InChI=1S/C12H12N2O4/c15-11-3-1-2-10(12(16)13-11)8-4-6-9(7-5-8)14(17)18/h4-7,10H,1-3H2,(H,13,15,16)	OYPIIJSKUMGOSW-UHFFFAOYSA-N	88458	3-(4-Nitrophenyl) azepane-2,7-dione::US20250388593, Example 61	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88458	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88458&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1827509	252660173							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125307	O=C1CCCC(C2=CC([N+](=O)[O-])CC=C2)C(=O)N1	InChI=1S/C12H14N2O4/c15-11-6-2-5-10(12(16)13-11)8-3-1-4-9(7-8)14(17)18/h1,3,7,9-10H,2,4-6H2,(H,13,15,16)	WXFRTFBUYNSEOJ-UHFFFAOYSA-N	88459	3-(3-Nitrophenyl) azepane-2,7-dione::US20250388593, Example 62	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88459	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88459&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6874399	252660174							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125308	O=C1CCCC(c2cc([N+](=O)[O-])ccc2Cl)C(=O)N1	InChI=1S/C12H11ClN2O4/c13-10-5-4-7(15(18)19)6-9(10)8-2-1-3-11(16)14-12(8)17/h4-6,8H,1-3H2,(H,14,16,17)	VQCWCQSMLCAWEN-UHFFFAOYSA-N	88460	3-(2-Chloro-5-nitrophenyl) azepane-2,7-dione::US20250388593, Example 63	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88460	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88460&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1818022	252660175							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125309	CC(=O)Nc1ccc(Cl)c(C2CCCC(=O)NC2=O)c1	InChI=1S/C14H15ClN2O3/c1-8(18)16-9-5-6-12(15)11(7-9)10-3-2-4-13(19)17-14(10)20/h5-7,10H,2-4H2,1H3,(H,16,18)(H,17,19,20)	CJQLSRZMIZUVBX-UHFFFAOYSA-N	88461	US20250388593, Example 65	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88461	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88461&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1218653	252660176							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125310	COC(=O)C(CCCCNC(=O)OCc1ccccc1)Oc1ccccc1[N+](=O)[O-]	InChI=1S/C21H24N2O7/c1-28-20(24)19(30-18-12-6-5-11-17(18)23(26)27)13-7-8-14-22-21(25)29-15-16-9-3-2-4-10-16/h2-6,9-12,19H,7-8,13-15H2,1H3,(H,22,25)	DCHRNNVLHYSWCR-UHFFFAOYSA-N	88462	Methyl 2-(2-nitrophenoxy)-6-(phenylmethoxycarbonylamino) hexanoate ::US20250388593, Example 66-1	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88462	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88462&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1321377	252660177							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125311	O=C(NCCCCC(Oc1ccccc1[N+](=O)[O-])C(=O)O)OCc1ccccc1	InChI=1S/C20H22N2O7/c23-19(24)18(29-17-11-5-4-10-16(17)22(26)27)12-6-7-13-21-20(25)28-14-15-8-2-1-3-9-15/h1-5,8-11,18H,6-7,12-14H2,(H,21,25)(H,23,24)	ZHSPSRDKHJGATK-UHFFFAOYSA-N	88463	2-(2-Nitrophenoxy)-6-(phenylmethoxycarbonylamino) hexanoic acid::US20250388593, Example 66-2	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88463	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88463&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			16189221	252660178							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125312	CC(C)(C)OC(=O)COc1cccc(C(=O)NC2CCCC(=O)NC2=O)c1F	InChI=1S/C19H23FN2O6/c1-19(2,3)28-15(24)10-27-13-8-4-6-11(16(13)20)17(25)21-12-7-5-9-14(23)22-18(12)26/h4,6,8,12H,5,7,9-10H2,1-3H3,(H,21,25)(H,22,23,26)	QFZGPABYHSLHGB-UHFFFAOYSA-N	88464	US20250388593, Example 67	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88464	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88464&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2295134	252660179							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125313	COc1c(OCC(=O)OC(C)(C)C)cccc1C(=O)NC1CCCC(=O)NC1=O	InChI=1S/C20H26N2O7/c1-20(2,3)29-16(24)11-28-14-9-5-7-12(17(14)27-4)18(25)21-13-8-6-10-15(23)22-19(13)26/h5,7,9,13H,6,8,10-11H2,1-4H3,(H,21,25)(H,22,23,26)	GOYBFZHAXQQDGF-UHFFFAOYSA-N	88465	US20250388593, Example 68	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88465	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88465&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1321526	252660180							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125314	CC(C)(C)OC(=O)COc1cccc(C(=O)NC2CCCC(=O)NC2=O)n1	InChI=1S/C18H23N3O6/c1-18(2,3)27-15(23)10-26-14-9-5-7-11(19-14)16(24)20-12-6-4-8-13(22)21-17(12)25/h5,7,9,12H,4,6,8,10H2,1-3H3,(H,20,24)(H,21,22,25)	VMCMHALPTLYJBD-UHFFFAOYSA-N	88466	US20250388593, Example 69	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88466	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88466&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2169083	252660181							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125315	Nc1cccc(C2CCCC(=O)NC2=O)c1	InChI=1S/C12H14N2O2/c13-9-4-1-3-8(7-9)10-5-2-6-11(15)14-12(10)16/h1,3-4,7,10H,2,5-6,13H2,(H,14,15,16)	JNAWEDPNYXKVCN-UHFFFAOYSA-N	88467	US20250388593, Example 70	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88467	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88467&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3206667	252660182							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125316	CC(=O)Nc1cccc(C2CCCC(=O)NC2=O)c1	InChI=1S/C14H16N2O3/c1-9(17)15-11-5-2-4-10(8-11)12-6-3-7-13(18)16-14(12)19/h2,4-5,8,12H,3,6-7H2,1H3,(H,15,17)(H,16,18,19)	LFYAKMDZGCKPGC-UHFFFAOYSA-N	88468	US20250388593, Example 71	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88468	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88468&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5709345	252660183							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125317	O=C4CCCC3(CCN(c2nc1ccc([N+](=O)[O-])cc1s2)C3)C(=O)N4	InChI=1S/C16H16N4O4S/c21-13-2-1-5-16(14(22)18-13)6-7-19(9-16)15-17-11-4-3-10(20(23)24)8-12(11)25-15/h3-4,8H,1-2,5-7,9H2,(H,18,21,22)	IKUMBYXJMQLYNB-UHFFFAOYSA-N	88469	US20250388593, Example 72	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88469	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88469&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			16194861	252660184							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125318	CCOC(=O)c1ccc2nc(N3CCC4(CCCC(=O)NC4=O)C3)sc2c1	InChI=1S/C19H21N3O4S/c1-2-26-16(24)12-5-6-13-14(10-12)27-18(20-13)22-9-8-19(11-22)7-3-4-15(23)21-17(19)25/h5-6,10H,2-4,7-9,11H2,1H3,(H,21,23,25)	ITTBTLNRQXLGBQ-UHFFFAOYSA-N	88471	US20250388593, Example 73	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88471	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88471&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			16194885	252660186							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125319	O=C1CCCC2(CCN(c3nc4ncccc4s3)C2)C(=O)N1	InChI=1S/C15H16N4O2S/c20-11-4-1-5-15(13(21)17-11)6-8-19(9-15)14-18-12-10(22-14)3-2-7-16-12/h2-3,7H,1,4-6,8-9H2,(H,17,20,21)	NYPHERRKGLGHJX-UHFFFAOYSA-N	88472	US20250388593, Example 74	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88472	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88472&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			16194898	252660187							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125320	O=C3CCCC2(CCN(c1ccc([N+](=O)[O-])cn1)C2)C(=O)N3	InChI=1S/C14H16N4O4/c19-12-2-1-5-14(13(20)16-12)6-7-17(9-14)11-4-3-10(8-15-11)18(21)22/h3-4,8H,1-2,5-7,9H2,(H,16,19,20)	PGHVTMGBYOJHLY-UHFFFAOYSA-N	88473	US20250388593, Example 75	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88473	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88473&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1472403	252660188							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125321	O=Cc1ccc(N2CCC3(CCCC(=O)NC3=O)C2)nc1	InChI=1S/C15H17N3O3/c19-9-11-3-4-12(16-8-11)18-7-6-15(10-18)5-1-2-13(20)17-14(15)21/h3-4,8-9H,1-2,5-7,10H2,(H,17,20,21)	BNFWNJNHNCEZRO-UHFFFAOYSA-N	88474	US20250388593, Example 76	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88474	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88474&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3653153	252660189							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125322	O=C3CCCC2(CCN(c1ncc([N+](=O)[O-])cc1Cl)C2)C(=O)N3	InChI=1S/C14H15ClN4O4/c15-10-6-9(19(22)23)7-16-12(10)18-5-4-14(8-18)3-1-2-11(20)17-13(14)21/h6-7H,1-5,8H2,(H,17,20,21)	ZVWOXCRRBRTJQD-UHFFFAOYSA-N	88475	US20250388593, Example 77	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88475	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88475&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2554360	252660190							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125323	Cc1cc([N+](=O)[O-])cnc1N3CCC2(CCCC(=O)NC2=O)C3	InChI=1S/C15H18N4O4/c1-10-7-11(19(22)23)8-16-13(10)18-6-5-15(9-18)4-2-3-12(20)17-14(15)21/h7-8H,2-6,9H2,1H3,(H,17,20,21)	PQVJGYVOTPWSJL-UHFFFAOYSA-N	88476	US20250388593, Example 78	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88476	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88476&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1002843	252660191							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125324	O=C3CCCC2(CCN(c1ncc([N+](=O)[O-])cc1C(F)(F)F)C2)C(=O)N3	InChI=1S/C15H15F3N4O4/c16-15(17,18)10-6-9(22(25)26)7-19-12(10)21-5-4-14(8-21)3-1-2-11(23)20-13(14)24/h6-7H,1-5,8H2,(H,20,23,24)	DHSFIKMIFCBMLC-UHFFFAOYSA-N	88477	US20250388593, Example 79	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88477	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88477&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2744571	252660192							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125325	O=C3CCCC2(CCN(c1ccc([N+](=O)[O-])cc1)C2)C(=O)N3	InChI=1S/C15H17N3O4/c19-13-2-1-7-15(14(20)16-13)8-9-17(10-15)11-3-5-12(6-4-11)18(21)22/h3-6H,1-2,7-10H2,(H,16,19,20)	QRFUFZQLIHJCTK-UHFFFAOYSA-N	88479	US20250388593, Example 80	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88479	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88479&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			24747934	252660193							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125326	Cc3cc(N2CCC1(CCCC(=O)NC1=O)C2)ccc3[N+](=O)[O-]	InChI=1S/C16H19N3O4/c1-11-9-12(4-5-13(11)19(22)23)18-8-7-16(10-18)6-2-3-14(20)17-15(16)21/h4-5,9H,2-3,6-8,10H2,1H3,(H,17,20,21)	NPDWLIIFQQTYKO-UHFFFAOYSA-N	88480	US20250388593, Example 81	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88480	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88480&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3578737	252660194							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125327	Cc1cc([N+](=O)[O-])ccc1N3CCC2(CCCC(=O)NC2=O)C3	InChI=1S/C16H19N3O4/c1-11-9-12(19(22)23)4-5-13(11)18-8-7-16(10-18)6-2-3-14(20)17-15(16)21/h4-5,9H,2-3,6-8,10H2,1H3,(H,17,20,21)	QQTJQNWLIHLKEF-UHFFFAOYSA-N	88481	US20250388593, Example 82	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88481	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88481&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6624952	252660195							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125328	O=C3CCCC2(CCN(c1ccc([N+](=O)[O-])cc1F)C2)C(=O)N3	InChI=1S/C15H16FN3O4/c16-11-8-10(19(22)23)3-4-12(11)18-7-6-15(9-18)5-1-2-13(20)17-14(15)21/h3-4,8H,1-2,5-7,9H2,(H,17,20,21)	VFFVSZIGWDYRDB-UHFFFAOYSA-N	88482	US20250388593, Example 83	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88482	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88482&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			9585284	252660196							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125329	O=C3CCCC2(CCN(c1ccc([N+](=O)[O-])cc1Cl)C2)C(=O)N3	InChI=1S/C15H16ClN3O4/c16-11-8-10(19(22)23)3-4-12(11)18-7-6-15(9-18)5-1-2-13(20)17-14(15)21/h3-4,8H,1-2,5-7,9H2,(H,17,20,21)	JKBZYWHSHNBKPF-UHFFFAOYSA-N	88484	US20250388593, Example 84	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88484	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88484&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			24891817	252660198							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125330	Nc1ccc2nc(N3CCC4(CCCC(=O)NC4=O)C3)sc2c1	InChI=1S/C16H18N4O2S/c17-10-3-4-11-12(8-10)23-15(18-11)20-7-6-16(9-20)5-1-2-13(21)19-14(16)22/h3-4,8H,1-2,5-7,9,17H2,(H,19,21,22)	BBMHHVVJWVRCNL-UHFFFAOYSA-N	88485	US20250388593, Example 85	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88485	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88485&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			16440949	252660199							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125331	Nc1ccc(N2CCC3(CCCC(=O)NC3=O)C2)c(F)c1	InChI=1S/C15H18FN3O2/c16-11-8-10(17)3-4-12(11)19-7-6-15(9-19)5-1-2-13(20)18-14(15)21/h3-4,8H,1-2,5-7,9,17H2,(H,18,20,21)	QPTLKDOBCXQMNM-UHFFFAOYSA-N	88486	US20250388593, Example 86	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88486	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88486&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3726853	252660200							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125332	CC(=O)Nc1ccc2nc(N3CCC4(CCCC(=O)NC4=O)C3)sc2c1	InChI=1S/C18H20N4O3S/c1-11(23)19-12-4-5-13-14(9-12)26-17(20-13)22-8-7-18(10-22)6-2-3-15(24)21-16(18)25/h4-5,9H,2-3,6-8,10H2,1H3,(H,19,23)(H,21,24,25)	FYMHPZVYCAPJHD-UHFFFAOYSA-N	88489	US20250388593, Example 87	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88489	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88489&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			44202176	252660203							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125333	CC(=O)Nc1ccc(N2CCC3(CCCC(=O)NC3=O)C2)c(F)c1	InChI=1S/C17H20FN3O3/c1-11(22)19-12-4-5-14(13(18)9-12)21-8-7-17(10-21)6-2-3-15(23)20-16(17)24/h4-5,9H,2-3,6-8,10H2,1H3,(H,19,22)(H,20,23,24)	RJYJCZHUNRSWQK-UHFFFAOYSA-N	88490	US20250388593, Example 88	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88490	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88490&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			44202203	252660204							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125334	CC(=O)N1CCN(Cc2ccc(N3CCC4(CCCC(=O)NC4=O)C3)nc2)CC1	InChI=1S/C21H29N5O3/c1-16(27)25-11-9-24(10-12-25)14-17-4-5-18(22-13-17)26-8-7-21(15-26)6-2-3-19(28)23-20(21)29/h4-5,13H,2-3,6-12,14-15H2,1H3,(H,23,28,29)	ITIQDOJGKCJAII-UHFFFAOYSA-N	88493	2-[5-[(4-Acetylpiperazin-1-yl)methyl]pyridin-2-yl]-2,7-diazaspiro[4.6]undecane-6,8-dione::US20250388593, Example 89	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88493	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88493&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			228252	252660206							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125335	CC(C)(C)OC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)C2)nc1	InChI=1S/C19H25N3O4/c1-18(2,3)26-16(24)13-6-7-14(20-11-13)22-10-9-19(12-22)8-4-5-15(23)21-17(19)25/h6-7,11H,4-5,8-10,12H2,1-3H3,(H,21,23,25)	RJKWCFDTMAGAGJ-UHFFFAOYSA-N	88494	US20250388593, Example 90-1	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88494	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88494&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			228383	252660207							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125336	CC(C)(C)OC(=O)c3ccc(N2CCC1(CCCC(=O)NC1=O)C2=O)nc3	InChI=1S/C19H23N3O5/c1-18(2,3)27-15(24)12-6-7-13(20-11-12)22-10-9-19(17(22)26)8-4-5-14(23)21-16(19)25/h6-7,11H,4-5,8-10H2,1-3H3,(H,21,23,25)	UHCXIOLRBMVBSJ-UHFFFAOYSA-N	88495	US20250388593, Example 90-2	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88495	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88495&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			45281081	252660208							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125337	CC(C)(C)OC(=O)c1ccnc(N2CCC3(CCCC(=O)NC3=O)C2)c1	InChI=1S/C19H25N3O4/c1-18(2,3)26-16(24)13-6-9-20-14(11-13)22-10-8-19(12-22)7-4-5-15(23)21-17(19)25/h6,9,11H,4-5,7-8,10,12H2,1-3H3,(H,21,23,25)	CKHMICNOAOPMDO-UHFFFAOYSA-N	88496	tert-Butyl 2-(6,8-dioxo-2,7-diazaspiro [4.6]undecan-2-yl) pyridine-4-carboxylate::US20250388593, Example 91	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88496	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88496&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			45281097	252660209							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125338	CC(C)(C)OC(=O)c1cccc(N2CCC3(CCCC(=O)NC3=O)C2)n1	InChI=1S/C19H25N3O4/c1-18(2,3)26-16(24)13-6-4-7-14(20-13)22-11-10-19(12-22)9-5-8-15(23)21-17(19)25/h4,6-7H,5,8-12H2,1-3H3,(H,21,23,25)	HXUVHGIEQXTHIA-UHFFFAOYSA-N	88497	tert-Butyl 6-(6,8-dioxo-2,7-diazaspiro [4.6]undecan-2-yl) pyridine-2-carboxylate::US20250388593, Example 92	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88497	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88497&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5469648	252660210							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125339	CC(C)(C)OC(=O)c1ccc(N2CCCC3(CCCC(=O)NC3=O)C2)nc1	InChI=1S/C20H27N3O4/c1-19(2,3)27-17(25)14-7-8-15(21-12-14)23-11-5-10-20(13-23)9-4-6-16(24)22-18(20)26/h7-8,12H,4-6,9-11,13H2,1-3H3,(H,22,24,26)	ONWARMZJYDVOFB-UHFFFAOYSA-N	88499	tert-Butyl 6-(7,9-dioxo-2,8-diazaspiro [5.6]dodecan-2-yl) pyridine-3-carboxylate::US20250388593, Example 93	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88499	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88499&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			45479968	252660212							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125340	CC(C)(C)OC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)CC2)nc1	InChI=1S/C20H27N3O4/c1-19(2,3)27-17(25)14-6-7-15(21-13-14)23-11-9-20(10-12-23)8-4-5-16(24)22-18(20)26/h6-7,13H,4-5,8-12H2,1-3H3,(H,22,24,26)	GZANGONEPGSRCG-UHFFFAOYSA-N	88504	tert-Butyl 6-(7,9-dioxo-3,8-diazaspiro [5.6]dodecan-3-yl) pyridine-3-carboxylate::US20250388593, Example 94	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88504	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88504&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46942448	252660214							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125341	CC(C)(C)OC(=O)c1cnc(N2CCC3(CCCC(=O)NC3=O)C2)s1	InChI=1S/C17H23N3O4S/c1-16(2,3)24-13(22)11-9-18-15(25-11)20-8-7-17(10-20)6-4-5-12(21)19-14(17)23/h9H,4-8,10H2,1-3H3,(H,19,21,23)	KCYSOSNBOOSDCQ-UHFFFAOYSA-N	88505	tert-Butyl 2-(6,8-dioxo-2,7-diazaspiro [4.6]undecan-2-yl)-1,3-thiazole-5-carboxylate::US20250388593, Example 95	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88505	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88505&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46942493	252660215							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125342	CNC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)C2)nc1	InChI=1S/C16H20N4O3/c1-17-14(22)11-4-5-12(18-9-11)20-8-7-16(10-20)6-2-3-13(21)19-15(16)23/h4-5,9H,2-3,6-8,10H2,1H3,(H,17,22)(H,19,21,23)	ZBLMYXWGILWIIX-UHFFFAOYSA-N	88506	6-(6,8-Dioxo-2,7-diazaspiro [4.6]undecan-2-yl)-N-methylpyridine-3-carboxamide::US20250388593, Example 96	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88506	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88506&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46942512	252660216							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125343	CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(N3CCC4(CCCC(=O)NC4=O)C3)nc2)CC1	InChI=1S/C24H33N5O5/c1-23(2,3)34-22(33)28-13-11-27(12-14-28)20(31)17-6-7-18(25-15-17)29-10-9-24(16-29)8-4-5-19(30)26-21(24)32/h6-7,15H,4-5,8-14,16H2,1-3H3,(H,26,30,32)	RSKYYMBEWKGYNQ-UHFFFAOYSA-N	88507	tert-Butyl 4-[6-(6,8-dioxo-2,7-diazaspiro [4.6]undecan-2-yl) pyridine-3-carbonyl]piperazine-1-carboxylate::US20250388593, Example 97	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88507	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88507&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46942664	252660217							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125344	CC(C)(C)OC(=O)N1CCN(C(=O)CN2CCC3(CCCC(=O)NC3=O)CC2=O)CC1	InChI=1S/C21H32N4O6/c1-20(2,3)31-19(30)24-11-9-23(10-12-24)17(28)14-25-8-7-21(13-16(25)27)6-4-5-15(26)22-18(21)29/h4-14H2,1-3H3,(H,22,26,29)	HDLHOBPPOQTVSJ-UHFFFAOYSA-N	88508	tert-Butyl 4-[2-(4,7,9-trioxo-3,8-diazaspiro [5.6]dodecan-3-yl) acetyl]piperazine-1-carboxylate::US20250388593, Example 98	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88508	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88508&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46942726	252660218							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125345	CC(C)(C)OC(=O)N1CCN(Cc2ccc(N3CCC4(CCCC(=O)NC4=O)C3)nc2)CC1	InChI=1S/C24H35N5O4/c1-23(2,3)33-22(32)28-13-11-27(12-14-28)16-18-6-7-19(25-15-18)29-10-9-24(17-29)8-4-5-20(30)26-21(24)31/h6-7,15H,4-5,8-14,16-17H2,1-3H3,(H,26,30,31)	NBJZYOQDHPXRLX-UHFFFAOYSA-N	88509	tert-Butyl 4-[[6-(6,8-dioxo-2,7-diazaspiro [4.6]undecan-2-yl) pyridin-3-yl]methyl]piperazine-1-carboxylate::US20250388593, Example 99	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88509	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88509&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46942899	252660219					C06049		1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125346	O=C1CCCC2(CCCN(C(=O)c3ccccc3)C2)C(=O)N1	InChI=1S/C17H20N2O3/c20-14-8-4-9-17(16(22)18-14)10-5-11-19(12-17)15(21)13-6-2-1-3-7-13/h1-3,6-7H,4-5,8-12H2,(H,18,20,22)	UUWCUFXINSQNDG-UHFFFAOYSA-N	88510	2-Benzoyl-2,8-diazaspiro [5.6]dodecane-7,9-dione::US20250388593, Example 104	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88510	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88510&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46943089	252660220							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125347	O=C1CCCC2(CCN(C(=O)c3ccccc3)CC2)C(=O)N1	InChI=1S/C17H20N2O3/c20-14-7-4-8-17(16(22)18-14)9-11-19(12-10-17)15(21)13-5-2-1-3-6-13/h1-3,5-6H,4,7-12H2,(H,18,20,22)	DTOPKLYQQDJIHD-UHFFFAOYSA-N	88511	3-Benzoyl-3,8-diazaspiro [5.6]dodecane-7,9-dione::US20250388593, Example 106	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88511	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88511&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46943096	252660221							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125348	CC(C)(C)OC(=O)CN1CCC2(CCCC(=O)NC2=O)CC1=O	InChI=1S/C16H24N2O5/c1-15(2,3)23-13(21)10-18-8-7-16(9-12(18)20)6-4-5-11(19)17-14(16)22/h4-10H2,1-3H3,(H,17,19,22)	BUEKFKCILYOXKL-UHFFFAOYSA-N	88512	tert-Butyl 2-(4,7,9-trioxo-3,8-diazaspiro [5.6]dodecan-3-yl) acetate::US20250388593, Example 107	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88512	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88512&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46943131	252660222							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125349	CC(C)(C)OC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)CC2=O)nc1	InChI=1S/C20H25N3O5/c1-19(2,3)28-17(26)13-6-7-14(21-12-13)23-10-9-20(11-16(23)25)8-4-5-15(24)22-18(20)27/h6-7,12H,4-5,8-11H2,1-3H3,(H,22,24,27)	PWSUHPWXNIIJIQ-UHFFFAOYSA-N	88513	tert-Butyl 6-(4,7,9-trioxo-3,8-diazaspiro [5.6]dodecan-3-yl) pyridine-3-carboxylate::US20250388593, Example 108	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88513	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88513&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46943460	252660223							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125350	CC(C)(C)OC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)CC2=O)cc1	InChI=1S/C21H26N2O5/c1-20(2,3)28-18(26)14-6-8-15(9-7-14)23-12-11-21(13-17(23)25)10-4-5-16(24)22-19(21)27/h6-9H,4-5,10-13H2,1-3H3,(H,22,24,27)	ONWGEIMUOXTXBN-UHFFFAOYSA-N	88514	tert-Butyl 4-(4,7,9-trioxo-3,8-diazaspiro [5.6]dodecan-3-yl) benzoate::US20250388593, Example 109	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88514&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46943491	252660224							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125351	CC(C)(C)OC(=O)c1cccc(N2CCC3(CCCC(=O)NC3=O)CC2=O)c1	InChI=1S/C21H26N2O5/c1-20(2,3)28-18(26)14-6-4-7-15(12-14)23-11-10-21(13-17(23)25)9-5-8-16(24)22-19(21)27/h4,6-7,12H,5,8-11,13H2,1-3H3,(H,22,24,27)	ZKQRQORYHGVSDV-UHFFFAOYSA-N	88515	tert-Butyl 3-(4,7,9-trioxo-3,8-diazaspiro [5.6]dodecan-3-yl) benzoate::US20250388593, Example 110	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88515	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88515&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46943685	252660225							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125352	CC(C)(C)OC(=O)c1ccc(CN2CCC3(CCCC(=O)NC3=O)CC2=O)cc1	InChI=1S/C22H28N2O5/c1-21(2,3)29-19(27)16-8-6-15(7-9-16)14-24-12-11-22(13-18(24)26)10-4-5-17(25)23-20(22)28/h6-9H,4-5,10-14H2,1-3H3,(H,23,25,28)	FHFIIWCMXBVFAS-UHFFFAOYSA-N	88516	tert-Butyl 4-[(4,7,9-trioxo-3,8-diazaspiro [5.6]dodecan-3-yl) methyl]benzoate::US20250388593, Example 111	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88516&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46943740	252660226							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125353	CC(C)(C)OC(=O)c1ccc(N2CC3(CCCC(=O)NC3=O)CC2=O)nc1	InChI=1S/C19H23N3O5/c1-18(2,3)27-16(25)12-6-7-13(20-10-12)22-11-19(9-15(22)24)8-4-5-14(23)21-17(19)26/h6-7,10H,4-5,8-9,11H2,1-3H3,(H,21,23,26)	ATLKYGQAURUMEJ-UHFFFAOYSA-N	88518	tert-Butyl 6-(3,6,8-trioxo-2,7-diazaspiro [4.6]undecan-2-yl) pyridine-3-carboxylate::US20250388593, Example 113	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88518&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46944097	252660228					C06049		1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125354	CC(C)(C)OC(=O)c1cnc(N2CCCC(=O)NC2=O)s1	InChI=1S/C13H17N3O4S/c1-13(2,3)20-10(18)8-7-14-12(21-8)16-6-4-5-9(17)15-11(16)19/h7H,4-6H2,1-3H3,(H,15,17,19)	OSGXCWPHMSTUKD-UHFFFAOYSA-N	88519	tert-Butyl 2-(2,4-dioxo-1,3-diazepan-1-yl) thiazole-5-carboxylate::US20250388593, Example 115	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88519	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88519&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46948025	252660229					C06049		1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125355	O=C3CCCN(c2nc1ccc([N+](=O)[O-])cc1s2)C(=O)N3	InChI=1S/C12H10N4O4S/c17-10-2-1-5-15(11(18)14-10)12-13-8-4-3-7(16(19)20)6-9(8)21-12/h3-4,6H,1-2,5H2,(H,14,17,18)	ZKAOLONZNKSZGF-UHFFFAOYSA-N	88520	1-(6-Nitro-1,3-benzothiazol-2-yl)-1,3-diazepane-2,4-dione::US20250388593, Example 116	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88520&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46948136	252660230							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125356	O=C1CCCN(c2ccc3ncccc3c2)C(=O)N1	InChI=1S/C14H13N3O2/c18-13-4-2-8-17(14(19)16-13)11-5-6-12-10(9-11)3-1-7-15-12/h1,3,5-7,9H,2,4,8H2,(H,16,18,19)	UFIIVBZJRGIEAR-UHFFFAOYSA-N	88521	1-Quinolin-6-yl-1,3-diazepane-2,4-dione::US20250388593, Example 117	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88521	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88521&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46948222	252660231							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125357	Nc1ccc2nc(N3CCCC(=O)NC3=O)sc2c1	InChI=1S/C12H12N4O2S/c13-7-3-4-8-9(6-7)19-12(14-8)16-5-1-2-10(17)15-11(16)18/h3-4,6H,1-2,5,13H2,(H,15,17,18)	OMNOIWMWSSZLRQ-UHFFFAOYSA-N	88522	1-(6-Amino-1,3-benzothiazol-2-yl)-1,3-diazepane-2,4-dione::US20250388593, Example 118	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88522&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46948249	252660232							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125358	CC(=O)Nc1ccc2nc(N3CCCC(=O)NC3=O)sc2c1	InChI=1S/C14H14N4O3S/c1-8(19)15-9-4-5-10-11(7-9)22-14(16-10)18-6-2-3-12(20)17-13(18)21/h4-5,7H,2-3,6H2,1H3,(H,15,19)(H,17,20,21)	GFTUBOIUECZKEX-UHFFFAOYSA-N	88523	N-[2-(2,4-Dioxo-1,3-diazepan-1-yl)-1,3-benzothiazol-6-yl]acetamide::US20250388593, Example 119	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88523	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88523&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46948506	252660233							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125359	CN(c1ccc([N+](=O)[O-])cc1)C1CCCC(=O)NC1=O	InChI=1S/C13H15N3O4/c1-15(9-5-7-10(8-6-9)16(19)20)11-3-2-4-12(17)14-13(11)18/h5-8,11H,2-4H2,1H3,(H,14,17,18)	DRFZXRDFBIDDIE-UHFFFAOYSA-N	88524	3-(N-Methyl-4-nitro-anilino) azepane-2,7-dione::US20250388593, Example 120	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88524&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46948544	252660234							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125360	CC(=O)Nc1ccc(N(C)C2CCCC(=O)NC2=O)cc1	InChI=1S/C15H19N3O3/c1-10(19)16-11-6-8-12(9-7-11)18(2)13-4-3-5-14(20)17-15(13)21/h6-9,13H,3-5H2,1-2H3,(H,16,19)(H,17,20,21)	NWNMXBADNFWWLU-UHFFFAOYSA-N	88525	N-[4-[(2,7-Dioxoazepan-3-yl)-methyl-amino]phenyl]acetamide::US20250388593, Example 121	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88525&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46948559	252660235							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125361	O=C1CCCC2(CCN(C(=O)c3ccccc3)C2)C(=O)N1	InChI=1S/C16H18N2O3/c19-13-7-4-8-16(15(21)17-13)9-10-18(11-16)14(20)12-5-2-1-3-6-12/h1-3,5-6H,4,7-11H2,(H,17,19,21)	XJAMQNSDYUTYJY-UHFFFAOYSA-N	88545	2-Benzoyl-2,7-diazaspiro [4.6]undecane-6,8-dione::US20250388593, Example 122	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88545	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88545&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			49791136	252660237					C06049		1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125362	CC(C)(C)OC(=O)c1cccc(N2CCC3(CCCC(=O)NC3=O)C2)c1	InChI=1S/C20H26N2O4/c1-19(2,3)26-17(24)14-6-4-7-15(12-14)22-11-10-20(13-22)9-5-8-16(23)21-18(20)25/h4,6-7,12H,5,8-11,13H2,1-3H3,(H,21,23,25)	ZAPJXIUEUHWKDB-UHFFFAOYSA-N	88569	tert-Butyl 3-(6,8-dioxo-2,7-diazaspiro [4.6]undecan-2-yl) benzoate::US20250388593, Example 123	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88569	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88569&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			648859	252660238							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125363	COc1ccnc(N2CCC3(CCCC(=O)NC3=O)C2)c1	InChI=1S/C15H19N3O3/c1-21-11-4-7-16-12(9-11)18-8-6-15(10-18)5-2-3-13(19)17-14(15)20/h4,7,9H,2-3,5-6,8,10H2,1H3,(H,17,19,20)	OEHYSXUIJHBOST-UHFFFAOYSA-N	88570	2-(4-Methoxy-2-pyridyl)-2,7-diazaspiro [4.6]undecane-6,8-dione::US20250388593, Example 125	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88570	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88570&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			654288	252660239							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125364	CC(C)(C)OC(=O)N1CCN(c2ccnc(N3CCC4(CCCC(=O)NC4=O)C3)c2)CC1	InChI=1S/C23H33N5O4/c1-22(2,3)32-21(31)27-13-11-26(12-14-27)17-6-9-24-18(15-17)28-10-8-23(16-28)7-4-5-19(29)25-20(23)30/h6,9,15H,4-5,7-8,10-14,16H2,1-3H3,(H,25,29,30)	SPAUOQXARUEDMA-UHFFFAOYSA-N	88571	tert-Butyl 4-[2-(6,8-dioxo-2,7-diazaspiro [4.6]undecan-2-yl)-4-pyridyl]piperazine-1-carboxylate::US20250388593, Example 126	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88571	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88571&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			661535	252660240							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125365	O=C1CCCC2(CCN(c3ncc(Br)cn3)C2)C(=O)N1	InChI=1S/C13H15BrN4O2/c14-9-6-15-12(16-7-9)18-5-4-13(8-18)3-1-2-10(19)17-11(13)20/h6-7H,1-5,8H2,(H,17,19,20)	CJULAIBQPLADGJ-UHFFFAOYSA-N	88572	2-(5-Bromopyrimidin-2-yl)-2,7-diazaspiro [4.6]undecane-6,8-dione::US20250388593, Example 127	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88572	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88572&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			91899117	252660241							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
125366	CC(C)(C)OC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)C2)cc1	InChI=1S/C20H26N2O4/c1-19(2,3)26-17(24)14-6-8-15(9-7-14)22-12-11-20(13-22)10-4-5-16(23)21-18(20)25/h6-9H,4-5,10-13H2,1-3H3,(H,21,23,25)	XLQLTRUFUJVMQN-UHFFFAOYSA-N	88573	tert-Butyl 4-(6,8-dioxo-2,7-diazaspiro [4.6]undecan-2-yl) benzoate::US20250388593, Example 128	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88573	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88573&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2998526	252660242							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126980	CC(C)(C)OC(=O)c1ccc(N2CCC3(CC=CC(=O)NC3=O)C2)nc1	InChI=1S/C19H23N3O4/c1-18(2,3)26-16(24)13-6-7-14(20-11-13)22-10-9-19(12-22)8-4-5-15(23)21-17(19)25/h4-7,11H,8-10,12H2,1-3H3,(H,21,23,25)	DJAODXYPGMGEAU-UHFFFAOYSA-N	88574	tert-Butyl 6-(6,8-dioxo-2,7-diazaspiro [4.6]undec-9-en-2-yl) pyridine-3-carboxylate::US20250388593, Example 131	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88574	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88574&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			28777	252660243							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126981	CC1(c2cccc(N)c2)CCCC(=O)NC1=O	InChI=1S/C13H16N2O2/c1-13(9-4-2-5-10(14)8-9)7-3-6-11(16)15-12(13)17/h2,4-5,8H,3,6-7,14H2,1H3,(H,15,16,17)	PLKIFJVJHYIDCX-UHFFFAOYSA-N	88575	3-(3-Aminophenyl)-3-methyl-azepane-2,7-dione::US20250388593, Example 133	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88575	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88575&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3239595	252660244							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126982	CC(=O)Nc1cccc(C2(C)CCCC(=O)NC2=O)c1	InChI=1S/C15H18N2O3/c1-10(18)16-12-6-3-5-11(9-12)15(2)8-4-7-13(19)17-14(15)20/h3,5-6,9H,4,7-8H2,1-2H3,(H,16,18)(H,17,19,20)	ZPLHUSAWYFZJKY-UHFFFAOYSA-N	88576	N-[3-(3-Methyl-2,7-dioxoazepan-3-yl)phenyl]acetamide::US20250388593, Example 134	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88576	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88576&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2948635	252660245							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126983	O=C1CCCC(n2nc(I)c3ccccc32)C(=O)N1	InChI=1S/C13H12IN3O2/c14-12-8-4-1-2-5-9(8)17(16-12)10-6-3-7-11(18)15-13(10)19/h1-2,4-5,10H,3,6-7H2,(H,15,18,19)	DUHVXLTVVMXRQJ-UHFFFAOYSA-N	88577	3-(3-Iodoindazol-1-yl)azepane-2,7-dione::US20250388593, Example 135	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88577	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88577&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1224769	252660246							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126984	CC(C)(C)OC(=O)/C=C/c1nn(C2CCCC(=O)NC2=O)c2ccccc12	InChI=1S/C20H23N3O4/c1-20(2,3)27-18(25)12-11-14-13-7-4-5-8-15(13)23(22-14)16-9-6-10-17(24)21-19(16)26/h4-5,7-8,11-12,16H,6,9-10H2,1-3H3,(H,21,24,26)	VDZUYXGWEODYRC-UHFFFAOYSA-N	88578	tert-Butyl (E)-3-[1-(2,7-oxazepan-3-yl)indazol-3-yl]-2-propenoate::US20250388593, Example 136	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88578	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88578&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1321203	252660247							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126985	CC(C)(C)OC(=O)CCc1nn(C2CCCC(=O)NC2=O)c2ccccc12	InChI=1S/C20H25N3O4/c1-20(2,3)27-18(25)12-11-14-13-7-4-5-8-15(13)23(22-14)16-9-6-10-17(24)21-19(16)26/h4-5,7-8,16H,6,9-12H2,1-3H3,(H,21,24,26)	DBLZWWDLFUMQOG-UHFFFAOYSA-N	88579	tert-Butyl 3-[1-(2,7-oxazepan-3-yl) indazol-3-yl]propanoate::US20250388593, Example 137	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88579	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88579&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1155311	252660248							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126986	CC(C)(C)OC(=O)Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21	InChI=1S/C19H23N3O5/c1-19(2,3)27-16(24)11-21-12-7-4-5-8-13(12)22(18(21)26)14-9-6-10-15(23)20-17(14)25/h4-5,7-8,14H,6,9-11H2,1-3H3,(H,20,23,25)	AMTBEDGVIMEHPO-UHFFFAOYSA-N	88580	tert-Butyl 2-[3-(2,7-dioxoazepan-3-yl)-2-oxo-benzimidazol-1-yl]acetate::US20250388593, Example 138	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88580	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88580&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1107087	252660249							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126987	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(Br)cc21	InChI=1S/C14H14BrN3O3/c1-17-11-7-8(15)5-6-9(11)18(14(17)21)10-3-2-4-12(19)16-13(10)20/h5-7,10H,2-4H2,1H3,(H,16,19,20)	ZPSDFLOWLARGIU-UHFFFAOYSA-N	88581	3-(5-Bromo-3-methyl-2-oxobenzimidazol-1-yl) azepane-2,7-dione::US20250388593, Example 139	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88581	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88581&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			9550171	252660250							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126988	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(/C=C/C(=O)OC(C)(C)C)cc21	InChI=1S/C21H25N3O5/c1-21(2,3)29-18(26)11-9-13-8-10-14-16(12-13)23(4)20(28)24(14)15-6-5-7-17(25)22-19(15)27/h8-12,15H,5-7H2,1-4H3,(H,22,25,27)	ZIWBQOJPAYDCMO-UHFFFAOYSA-N	88582	tert-Butyl (E)-3-[1-(2,7-oxazepan-3-yl)-3-methyl-2-oxo-benzimidazol-5-yl]-2-propenoate::US20250388593, Example 140	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88582	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88582&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2203170	252660251							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126989	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(CCC(=O)OC(C)(C)C)cc21	InChI=1S/C21H27N3O5/c1-21(2,3)29-18(26)11-9-13-8-10-14-16(12-13)23(4)20(28)24(14)15-6-5-7-17(25)22-19(15)27/h8,10,12,15H,5-7,9,11H2,1-4H3,(H,22,25,27)	MBZPXUIIWSOTLI-UHFFFAOYSA-N	88583	tert-Butyl 3-[1-(2,7-oxazepan-3-yl)-3-methyl-2-oxo-benzimidazol-5-yl]propanoate::US20250388593, Example 141	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88583	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88583&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4884388	252660252							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126990	NC(=O)c1nn(-c2ccc(C(=O)NCCOCCOCCNC(=O)c3ccnc(N4CCC5(CCCC(=O)NC5=O)C4)c3)cc2)cc1NC(=O)c1coc(-c2ccnc(NCC3CC3)c2)n1	InChI=1S/C45H50N12O9/c46-39(59)38-33(52-42(62)34-26-66-43(53-34)31-10-13-47-35(22-31)51-24-28-3-4-28)25-57(55-38)32-7-5-29(6-8-32)40(60)49-15-18-64-20-21-65-19-16-50-41(61)30-9-14-48-36(23-30)56-17-12-45(27-56)11-1-2-37(58)54-44(45)63/h5-10,13-14,22-23,25-26,28H,1-4,11-12,15-21,24,27H2,(H2,46,59)(H,47,51)(H,49,60)(H,50,61)(H,52,62)(H,54,58,63)	FYBLELBQGDYJRX-UHFFFAOYSA-N	88584	N-[3-Carbamoyl-1-[4-[2-[2-[2-[[2-(6,8-dioxo-2,7-diazaspiro [4.6]undecan-2-yl) pyridine-4-carbonyl]amino]ethoxy]ethoxy]ethylcarbamoyl]phenyl]-pyrazol-4-yl]-2-[2-(cyclopropylmethylamino)-4-pyridyl]oxazole-4-carboxamide::US20250388593, Example 142	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88584	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88584&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4235517	252660253							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126991	NC(=O)c1nn(-c2ccc(C(=O)NCCOCCOCCNC(=O)c3ccc(N4CCC5(CCCC(=O)NC5=O)CC4=O)nc3)cc2)cc1NC(=O)c1coc(-c2ccnc(NCC3CC3)c2)n1	InChI=1S/C46H50N12O10/c47-40(61)39-33(53-43(64)34-27-68-44(54-34)30-11-14-48-35(22-30)51-24-28-3-4-28)26-58(56-39)32-8-5-29(6-9-32)41(62)49-15-18-66-20-21-67-19-16-50-42(63)31-7-10-36(52-25-31)57-17-13-46(23-38(57)60)12-1-2-37(59)55-45(46)65/h5-11,14,22,25-28H,1-4,12-13,15-21,23-24H2,(H2,47,61)(H,48,51)(H,49,62)(H,50,63)(H,53,64)(H,55,59,65)	NFCOSKFJMFPFAM-UHFFFAOYSA-N	88585	N-[3-Carbamoyl-1-[4-[2-[2-[2-[[6-(4,7,9-trioxo-3,8-diazaspiro [5.6]dodecan-3-yl) pyridine-3-carbonyl]amino]ethoxy]ethoxy]ethylcarbamoyl]phenyl]pyrazol-4-yl]-2-[2-(cyclopropylmethylamino)-4-pyridyl]oxazole-4-carboxamide::US20250388593, Example 143	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88585	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88585&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1792505	252660254							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126992	NC(=O)c1nn(-c2ccc(C(=O)NCCOCCOCCNC(=O)CN3CCC4(CCCC(=O)NC4=O)CC3=O)cc2)cc1NC(=O)c1coc(-c2ccnc(NCC3CC3)c2)n1	InChI=1S/C42H49N11O10/c43-37(57)36-30(48-39(59)31-25-63-40(49-31)28-9-12-44-32(20-28)47-22-26-3-4-26)23-53(51-36)29-7-5-27(6-8-29)38(58)46-14-17-62-19-18-61-16-13-45-34(55)24-52-15-11-42(21-35(52)56)10-1-2-33(54)50-41(42)60/h5-9,12,20,23,25-26H,1-4,10-11,13-19,21-22,24H2,(H2,43,57)(H,44,47)(H,45,55)(H,46,58)(H,48,59)(H,50,54,60)	IVPQWCMBAOAZKG-UHFFFAOYSA-N	88586	N-[3-Carbamoyl-1-[4-[2-[2-[2-[[2-(4,7,9-trioxo-3,8-diazaspiro [5.6]dodecan-3-yl) acetyl]amino]ethoxy]ethoxy]ethylcarbamoyl]phenyl]pyrazol-4-yl]-2-[2-(cyclopropylmethylamino)-4-pyridyl]oxazole-4-carboxamide::US20250388593, Example 144	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88586	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88586&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1221905	252660255							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126993	CC(C)(C)OC(=O)NCCCCCCCc1cn(C2CCCC(=O)NC2=O)nn1	InChI=1S/C20H33N5O4/c1-20(2,3)29-19(28)21-13-8-6-4-5-7-10-15-14-25(24-23-15)16-11-9-12-17(26)22-18(16)27/h14,16H,4-13H2,1-3H3,(H,21,28)(H,22,26,27)	RVHOPIXMVPJGNR-UHFFFAOYSA-N	88588	US20250388593, Example 147	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88588	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88588&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5210018	252660256							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126994	O=C1CCCC(n2cc(CCCCCCCC(=O)OCc3ccccc3)nn2)C(=O)N1	InChI=1S/C23H30N4O4/c28-21-14-9-13-20(23(30)24-21)27-16-19(25-26-27)12-7-2-1-3-8-15-22(29)31-17-18-10-5-4-6-11-18/h4-6,10-11,16,20H,1-3,7-9,12-15,17H2,(H,24,28,30)	JNALMWPRMWEUMA-UHFFFAOYSA-N	88589	US20250388593, Example 148	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88589	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88589&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1214669	252660257							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126995	CC(C)(C)OC(=O)COc1ccccc1-c1cn(C2CCCC(=O)NC2=O)nn1	InChI=1S/C20H24N4O5/c1-20(2,3)29-18(26)12-28-16-9-5-4-7-13(16)14-11-24(23-22-14)15-8-6-10-17(25)21-19(15)27/h4-5,7,9,11,15H,6,8,10,12H2,1-3H3,(H,21,25,27)	VEQCCCXPTJKADU-UHFFFAOYSA-N	88590	US20250388593, Example 149	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88590	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88590&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			91899118	252660258							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126996	CC(C)(C)OC(=O)NCCCCCCc1ccc(-c2cn(C3CCCC(=O)NC3=O)nn2)cc1	InChI=1S/C25H35N5O4/c1-25(2,3)34-24(33)26-16-7-5-4-6-9-18-12-14-19(15-13-18)20-17-30(29-28-20)21-10-8-11-22(31)27-23(21)32/h12-15,17,21H,4-11,16H2,1-3H3,(H,26,33)(H,27,31,32)	ZWYHDXDPZPRVGL-UHFFFAOYSA-N	88591	tert-Butyl N-[6-[4-[1-(2,7-dioxoazepan-3-yl) triazol-4-yl]phenyl]hexyl]carbamate::US20250388593, Example 150	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88591	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88591&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1442634	252660259							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126997	Cn1ccc2c(C(=O)N3CCC4(CCCC(=O)NC4=O)C3)cccc21	InChI=1S/C19H21N3O3/c1-21-10-7-13-14(4-2-5-15(13)21)17(24)22-11-9-19(12-22)8-3-6-16(23)20-18(19)25/h2,4-5,7,10H,3,6,8-9,11-12H2,1H3,(H,20,23,25)	NBOHAJJESDZFSB-UHFFFAOYSA-N	88592	US20250388593, Example 151	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88592	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88592&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1050448	242053815							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
126998	O=C1CCCC2(CCN(C(=O)c3ccc4scnc4c3)C2)C(=O)N1	InChI=1S/C17H17N3O3S/c21-14-2-1-5-17(16(23)19-14)6-7-20(9-17)15(22)11-3-4-13-12(8-11)18-10-24-13/h3-4,8,10H,1-2,5-7,9H2,(H,19,21,23)	FIVVXONGENHMPW-UHFFFAOYSA-N	88593	US20250388593, Example 152	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88593	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88593&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2838222	252660260							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127000	O=C1CCCC2(CCN(C(=O)c3cnn4ccccc34)C2)C(=O)N1	InChI=1S/C17H18N4O3/c22-14-5-3-6-17(16(24)19-14)7-9-20(11-17)15(23)12-10-18-21-8-2-1-4-13(12)21/h1-2,4,8,10H,3,5-7,9,11H2,(H,19,22,24)	LOHLEKZBJJGRFN-UHFFFAOYSA-N	88594	US20250388593, Example 153	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88594	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88594&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2898120	252660261							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127001	O=C1CCCC2(CCN(C(=O)c3nc4ccccc4o3)C2)C(=O)N1	InChI=1S/C17H17N3O4/c21-13-6-3-7-17(16(23)19-13)8-9-20(10-17)15(22)14-18-11-4-1-2-5-12(11)24-14/h1-2,4-5H,3,6-10H2,(H,19,21,23)	MGQWJXIYXVJOQL-UHFFFAOYSA-N	88595	US20250388593, Example 154	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88595	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88595&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1256628	252660262							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127002	Nc1ccc(C(=O)N2CCC3(CCCC(=O)NC3=O)C2)cc1	InChI=1S/C16H19N3O3/c17-12-5-3-11(4-6-12)14(21)19-9-8-16(10-19)7-1-2-13(20)18-15(16)22/h3-6H,1-2,7-10,17H2,(H,18,20,22)	PGGMUBGUAWPCQH-UHFFFAOYSA-N	88596	US20250388593, Example 155	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88596	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88596&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1343565	252660263							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127003	Cc1ccc(NC(=O)NCc2ccccc2C(=O)N2CCC3(CCCC(=O)NC3=O)C2)cc1Cl	InChI=1S/C25H27ClN4O4/c1-16-8-9-18(13-20(16)26)28-24(34)27-14-17-5-2-3-6-19(17)22(32)30-12-11-25(15-30)10-4-7-21(31)29-23(25)33/h2-3,5-6,8-9,13H,4,7,10-12,14-15H2,1H3,(H2,27,28,34)(H,29,31,33)	XYYGMEWJRDEWQX-UHFFFAOYSA-N	88597	US20250388593, Example 156	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88597	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88597&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5423078	252660264							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127004	Cc1ccc(NC(=O)NCc2ccc(C(=O)N3CCC4(CCCC(=O)NC4=O)C3)cc2)cc1Cl	InChI=1S/C25H27ClN4O4/c1-16-4-9-19(13-20(16)26)28-24(34)27-14-17-5-7-18(8-6-17)22(32)30-12-11-25(15-30)10-2-3-21(31)29-23(25)33/h4-9,13H,2-3,10-12,14-15H2,1H3,(H2,27,28,34)(H,29,31,33)	SQZKJBKMSVVLRL-UHFFFAOYSA-N	88598	US20250388593, Example 157	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88598	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88598&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1332281	252660265							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127005	CC(C)(C)OC(=O)NCCCCCCc1cccc(C(=O)N2CCC3(CCCC(=O)NC3=O)C2)c1	InChI=1S/C27H39N3O5/c1-26(2,3)35-25(34)28-16-7-5-4-6-10-20-11-8-12-21(18-20)23(32)30-17-15-27(19-30)14-9-13-22(31)29-24(27)33/h8,11-12,18H,4-7,9-10,13-17,19H2,1-3H3,(H,28,34)(H,29,31,33)	IGTUIZVALGZFOY-UHFFFAOYSA-N	88599	US20250388593, Example 158	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88599	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88599&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1187196	252660266							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127006	CC(C)(C)OC(=O)NCCCCCCc1ccccc1C(=O)N1CCC2(CCCC(=O)NC2=O)C1	InChI=1S/C27H39N3O5/c1-26(2,3)35-25(34)28-17-9-5-4-6-11-20-12-7-8-13-21(20)23(32)30-18-16-27(19-30)15-10-14-22(31)29-24(27)33/h7-8,12-13H,4-6,9-11,14-19H2,1-3H3,(H,28,34)(H,29,31,33)	OBENXTUAFFRQOL-UHFFFAOYSA-N	88600	US20250388593, Example 159	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88600	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88600&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			91899119	252660267							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127007	CC(C)(C)OC(=O)NCCCCCCc1ccc(C(=O)N2CCC3(CCCC(=O)NC3=O)C2)cc1Cl	InChI=1S/C27H38ClN3O5/c1-26(2,3)36-25(35)29-15-7-5-4-6-9-19-11-12-20(17-21(19)28)23(33)31-16-14-27(18-31)13-8-10-22(32)30-24(27)34/h11-12,17H,4-10,13-16,18H2,1-3H3,(H,29,35)(H,30,32,34)	LUYCXUJLIJBSTP-UHFFFAOYSA-N	88601	US20250388593, Example 160	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88601	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88601&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6621000	252660268							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127008	CC(C)(C)OC(=O)NCCCCCCc1cccc2c(C(=O)N3CCC4(CCCC(=O)NC4=O)C3)cccc12	InChI=1S/C31H41N3O5/c1-30(2,3)39-29(38)32-19-7-5-4-6-11-22-12-8-14-24-23(22)13-9-15-25(24)27(36)34-20-18-31(21-34)17-10-16-26(35)33-28(31)37/h8-9,12-15H,4-7,10-11,16-21H2,1-3H3,(H,32,38)(H,33,35,37)	LVAHAYMTMJYTSS-UHFFFAOYSA-N	88602	US20250388593, Example 161	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88602	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88602&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3617229	252660269							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127009	CC(C)(C)OC(=O)NCCCCCCn1ccc2c(C(=O)N3CCC4(CCCC(=O)NC4=O)C3)cccc21	InChI=1S/C29H40N4O5/c1-28(2,3)38-27(37)30-16-6-4-5-7-17-32-18-13-21-22(10-8-11-23(21)32)25(35)33-19-15-29(20-33)14-9-12-24(34)31-26(29)36/h8,10-11,13,18H,4-7,9,12,14-17,19-20H2,1-3H3,(H,30,37)(H,31,34,36)	IZBCKSNPQCCAJK-UHFFFAOYSA-N	88603	US20250388593, Example 162	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88603	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88603&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			91899120	252660270							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127010	O=C1NC(=O)C2(NC3=CC(Br)CC=C3)CCC1CC2	InChI=1S/C14H17BrN2O2/c15-10-2-1-3-11(8-10)17-14-6-4-9(5-7-14)12(18)16-13(14)19/h1,3,8-10,17H,2,4-7H2,(H,16,18,19)	SXHNETXEGZUDHH-UHFFFAOYSA-N	88605	1-(3-Bromoanilino)-3-azabicyclo [3.2.2]nonane-2,4-dione::US20250388593, Example 165	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88605	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88605&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4881126	252660272							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127011	O=C1NC(=O)C2(c3ccc(Br)cc3)CCC1CC2	InChI=1S/C14H14BrNO2/c15-11-3-1-10(2-4-11)14-7-5-9(6-8-14)12(17)16-13(14)18/h1-4,9H,5-8H2,(H,16,17,18)	DTRCQKJSPGARRW-UHFFFAOYSA-N	88606	1-(4-Bromophenyl)-3-azabicyclo [3.2.2]nonane-2,4-dione ::US20250388593, Example 167	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88606	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88606&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2370680	252660273							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127012	CC(C)(C)OC(=O)N1CC=C(c2cnc(N3CCC4(CCCC(=O)NC4=O)C3)nc2)CC1	InChI=1S/C23H31N5O4/c1-22(2,3)32-21(31)27-10-6-16(7-11-27)17-13-24-20(25-14-17)28-12-9-23(15-28)8-4-5-18(29)26-19(23)30/h6,13-14H,4-5,7-12,15H2,1-3H3,(H,26,29,30)	VBDAMQPAHNTGTH-UHFFFAOYSA-N	88607	US20250388593, Example 168-2	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88607	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88607&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2577649	252660274							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127014	O=C1NC(=O)C2(c3ccc(Br)cc3)CCC1O2	InChI=1S/C12H10BrNO3/c13-8-3-1-7(2-4-8)12-6-5-9(17-12)10(15)14-11(12)16/h1-4,9H,5-6H2,(H,14,15,16)	RZLABNKXNMPBIF-UHFFFAOYSA-N	88608	1-(4-Bromophenyl)-8-oxa-3-azabicyclo [3.2.1]octane-2,4-dione::US20250388593, Example 173	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88608	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88608&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3503149	252660275							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127015	COC(=O)c1cc2c(N3CCC4(CCCC(=O)NC4=O)C3)ncnc2s1	InChI=1S/C17H18N4O4S/c1-25-15(23)11-7-10-13(18-9-19-14(10)26-11)21-6-5-17(8-21)4-2-3-12(22)20-16(17)24/h7,9H,2-6,8H2,1H3,(H,20,22,24)	ZCLMZCSOLADXQB-UHFFFAOYSA-N	88609	US20250388593, Example 176	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88609	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88609&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2078942	252660276							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127016	N#Cc1cc([N+](=O)[O-])ccc1N3CCC2(CCCC(=O)NC2=O)C3	InChI=1S/C16H16N4O4/c17-9-11-8-12(20(23)24)3-4-13(11)19-7-6-16(10-19)5-1-2-14(21)18-15(16)22/h3-4,8H,1-2,5-7,10H2,(H,18,21,22)	WLSTZEYYLZEFRH-UHFFFAOYSA-N	88610	US20250388593, Example 177	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88610	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88610&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2411726	252660277							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127017	CC(=O)C1CCc2nc(N3CCC4(CCCC(=O)NC4=O)C3)ncc2C1	InChI=1S/C19H24N4O3/c1-12(24)13-4-5-15-14(9-13)10-20-18(21-15)23-8-7-19(11-23)6-2-3-16(25)22-17(19)26/h10,13H,2-9,11H2,1H3,(H,22,25,26)	TVZALIOMMQIYHM-UHFFFAOYSA-N	88611	US20250388593, Example 178	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88611	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88611&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1203284	252660278							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127018	N#Cc1ccc(N2CCC3(CCCC(=O)NC3=O)C2)cc1	InChI=1S/C16H17N3O2/c17-10-12-3-5-13(6-4-12)19-9-8-16(11-19)7-1-2-14(20)18-15(16)21/h3-6H,1-2,7-9,11H2,(H,18,20,21)	PPHNMMGDLHXZJQ-UHFFFAOYSA-N	88612	US20250388593, Example 179	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88612	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88612&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4834494	252660279							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127019	Cn1c(C(=O)OC(C)(C)C)cc2c(N3CCC4(CCCC(=O)NC4=O)C3)ncnc21	InChI=1S/C21H27N5O4/c1-20(2,3)30-18(28)14-10-13-16(25(14)4)22-12-23-17(13)26-9-8-21(11-26)7-5-6-15(27)24-19(21)29/h10,12H,5-9,11H2,1-4H3,(H,24,27,29)	XUSSIZNHKCULNN-UHFFFAOYSA-N	88613	US20250388593, Example 180	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88613	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88613&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2442208	252660280							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127020	Nc1nccc(N2CCC3(CCCC(=O)NC3=O)C2)n1	InChI=1S/C13H17N5O2/c14-12-15-6-3-9(16-12)18-7-5-13(8-18)4-1-2-10(19)17-11(13)20/h3,6H,1-2,4-5,7-8H2,(H2,14,15,16)(H,17,19,20)	ULCVXFLTXNCTDN-UHFFFAOYSA-N	88614	US20250388593, Example 182	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88614	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88614&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2508583	252660281							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127021	Nc1nccc(N2CCC3(CCCC(=O)NC3=O)C2)n1	InChI=1S/C13H17N5O2/c14-12-15-6-3-9(16-12)18-7-5-13(8-18)4-1-2-10(19)17-11(13)20/h3,6H,1-2,4-5,7-8H2,(H2,14,15,16)(H,17,19,20)	ULCVXFLTXNCTDN-UHFFFAOYSA-N	88615	US20250388593, Example 183	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88615	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88615&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2575495	252660282							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127022	CC(C)(C)OC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)C2)nn1	InChI=1S/C18H24N4O4/c1-17(2,3)26-15(24)12-6-7-13(21-20-12)22-10-9-18(11-22)8-4-5-14(23)19-16(18)25/h6-7H,4-5,8-11H2,1-3H3,(H,19,23,25)	URRAFTYMNOSAON-UHFFFAOYSA-N	88616	US20250388593, Example 184	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88616	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88616&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3427699	252660283							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127023	CC(C)(C)OC(=O)NCCCNc1nccc(N2CCC3(CCCC(=O)NC3=O)C2)n1	InChI=1S/C21H32N6O4/c1-20(2,3)31-19(30)24-11-5-10-22-18-23-12-7-15(25-18)27-13-9-21(14-27)8-4-6-16(28)26-17(21)29/h7,12H,4-6,8-11,13-14H2,1-3H3,(H,24,30)(H,22,23,25)(H,26,28,29)	YCMJXHPLOBXXNW-UHFFFAOYSA-N	88617	US20250388593, Example 185	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88617	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88617&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			7801294	252660284							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127024	CC(C)(C)OC(=O)NCCCCCCCCn1ccc2c(N3CCC4(CCCC(=O)NC4=O)C3)ccnc21	InChI=1S/C29H43N5O4/c1-28(2,3)38-27(37)31-16-8-6-4-5-7-9-18-33-19-13-22-23(12-17-30-25(22)33)34-20-15-29(21-34)14-10-11-24(35)32-26(29)36/h12-13,17,19H,4-11,14-16,18,20-21H2,1-3H3,(H,31,37)(H,32,35,36)	BROAFZPSAPJRDF-UHFFFAOYSA-N	88618	US20250388593, Example 186	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88618	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88618&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1044054	252660285							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127025	COc1ccc2nc(N3CCC4(CCCC(=O)NC4=O)C3)sc2c1	InChI=1S/C17H19N3O3S/c1-23-11-4-5-12-13(9-11)24-16(18-12)20-8-7-17(10-20)6-2-3-14(21)19-15(17)22/h4-5,9H,2-3,6-8,10H2,1H3,(H,19,21,22)	BMTRAUNHUFDJQA-UHFFFAOYSA-N	88619	US20250388593, Example 187	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88619	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88619&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5045937	252660286							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127026	COc1ccc2sc(N3CCC4(CCCC(=O)NC4=O)C3)nc2c1	InChI=1S/C17H19N3O3S/c1-23-11-4-5-13-12(9-11)18-16(24-13)20-8-7-17(10-20)6-2-3-14(21)19-15(17)22/h4-5,9H,2-3,6-8,10H2,1H3,(H,19,21,22)	FTXBZZGJMZYDPX-UHFFFAOYSA-N	88620	US20250388593, Example 188	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88620	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88620&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			91899121	252660287							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127027	COc1cccc2sc(N3CCC4(CCCC(=O)NC4=O)C3)nc12	InChI=1S/C17H19N3O3S/c1-23-11-4-2-5-12-14(11)19-16(24-12)20-9-8-17(10-20)7-3-6-13(21)18-15(17)22/h2,4-5H,3,6-10H2,1H3,(H,18,21,22)	ADQAQIADMURXSX-UHFFFAOYSA-N	88621	US20250388593, Example 189	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88621	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88621&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5738090	252660288							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127028	CC(C)(C)OC(=O)N1CCc2c(ncnc2N2CCC3(CCCC(=O)NC3=O)C2)C1	InChI=1S/C21H29N5O4/c1-20(2,3)30-19(29)25-9-6-14-15(11-25)22-13-23-17(14)26-10-8-21(12-26)7-4-5-16(27)24-18(21)28/h13H,4-12H2,1-3H3,(H,24,27,28)	NWKFMOURUWMWBD-UHFFFAOYSA-N	88622	US20250388593, Example 190	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88622	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88622&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5022720	252660289							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127029	CC(C)(C)OC(=O)COc1ccccc1-c1cn(C2CCCC(=O)NC2=O)nn1	InChI=1S/C20H24N4O5/c1-20(2,3)29-18(26)12-28-16-9-5-4-7-13(16)14-11-24(23-22-14)15-8-6-10-17(25)21-19(15)27/h4-5,7,9,11,15H,6,8,10,12H2,1-3H3,(H,21,25,27)	VEQCCCXPTJKADU-UHFFFAOYSA-N	88623	tert-Butyl 2-[2-[1-(2,7-dioxoazepan-3-yl) triazol-4-yl]phenoxy]acetate::US20250388593, Example 191	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88623	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88623&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2963653	252660290							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127030	COc1ccc(C#N)c(N2CCC3(CCCC(=O)NC3=O)C2)c1	InChI=1S/C17H19N3O3/c1-23-13-5-4-12(10-18)14(9-13)20-8-7-17(11-20)6-2-3-15(21)19-16(17)22/h4-5,9H,2-3,6-8,11H2,1H3,(H,19,21,22)	GDUAVMBMCPGAQU-UHFFFAOYSA-N	88624	US20250388593, Example 192	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88624	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88624&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2946035	252660291							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127031	CC(C)(C)OC(=O)COc1ccc(C#N)c(N2CCC3(CCCC(=O)NC3=O)C2)c1	InChI=1S/C22H27N3O5/c1-21(2,3)30-19(27)13-29-16-7-6-15(12-23)17(11-16)25-10-9-22(14-25)8-4-5-18(26)24-20(22)28/h6-7,11H,4-5,8-10,13-14H2,1-3H3,(H,24,26,28)	DVQKNFCCPYVUDL-UHFFFAOYSA-N	88625	US20250388593, Example 193	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88625	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88625&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3216691	252660292							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127032	CC(C)(C)OC(=O)CCCCCCCCCOc1ccc(C#N)c(N2CCC3(CCCC(=O)NC3=O)C2)c1	InChI=1S/C30H43N3O5/c1-29(2,3)38-27(35)13-9-7-5-4-6-8-10-19-37-24-15-14-23(21-31)25(20-24)33-18-17-30(22-33)16-11-12-26(34)32-28(30)36/h14-15,20H,4-13,16-19,22H2,1-3H3,(H,32,34,36)	AHEPBFHELXHSDI-UHFFFAOYSA-N	88626	US20250388593, Example 194	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88626	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88626&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1100660	252660293							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127033	CC(C)(C)OC(=O)CCCCCCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21	InChI=1S/C25H35N3O5/c1-25(2,3)33-22(30)16-7-5-4-6-10-17-27-18-12-8-9-13-19(18)28(24(27)32)20-14-11-15-21(29)26-23(20)31/h8-9,12-13,20H,4-7,10-11,14-17H2,1-3H3,(H,26,29,31)	RVHQTWFOORQKIY-UHFFFAOYSA-N	88627	tert-Butyl 8-[3-(2,7-dioxoazepan-3-yl)-2-oxobenzimidazol-1-yl]octanoate::US20250388593, Example 195	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88627	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88627&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3130267	252660294							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127034	CC(C)(C)OC(=O)NCCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21	InChI=1S/C21H28N4O5/c1-21(2,3)30-19(28)22-12-7-13-24-14-8-4-5-9-15(14)25(20(24)29)16-10-6-11-17(26)23-18(16)27/h4-5,8-9,16H,6-7,10-13H2,1-3H3,(H,22,28)(H,23,26,27)	KLPCWRGHWFJFFD-UHFFFAOYSA-N	88628	US20250388593, Example 196	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88628	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88628&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			16193930	252660295							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127035	CC(C)(C)OC(=O)NCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21	InChI=1S/C20H26N4O5/c1-20(2,3)29-18(27)21-11-12-23-13-7-4-5-8-14(13)24(19(23)28)15-9-6-10-16(25)22-17(15)26/h4-5,7-8,15H,6,9-12H2,1-3H3,(H,21,27)(H,22,25,26)	JDLCLGLNJIICNC-UHFFFAOYSA-N	88629	US20250388593, Example 197	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88629	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88629&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			16194436	252660296							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127036	CC(C)(C)OC(=O)NCCCCCCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21	InChI=1S/C25H36N4O5/c1-25(2,3)34-23(32)26-16-9-5-4-6-10-17-28-18-12-7-8-13-19(18)29(24(28)33)20-14-11-15-21(30)27-22(20)31/h7-8,12-13,20H,4-6,9-11,14-17H2,1-3H3,(H,26,32)(H,27,30,31)	UDSKZJIPLUMMOQ-UHFFFAOYSA-N	88630	US20250388593, Example 198	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88630	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88630&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1475893	252660297							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127037	CC(C)(C)OC(=O)NCCOCCOCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21	InChI=1S/C24H34N4O7/c1-24(2,3)35-22(31)25-11-13-33-15-16-34-14-12-27-17-7-4-5-8-18(17)28(23(27)32)19-9-6-10-20(29)26-21(19)30/h4-5,7-8,19H,6,9-16H2,1-3H3,(H,25,31)(H,26,29,30)	QNBHRKZGWGPJEU-UHFFFAOYSA-N	88631	US20250388593, Example 199	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88631	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88631&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3296286	252660298							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127038	O=C1NCCCCC1N1C(=O)NC2CC=CN=C21	InChI=1S/C12H16N4O2/c17-11-9(5-1-2-6-14-11)16-10-8(15-12(16)18)4-3-7-13-10/h3,7-9H,1-2,4-6H2,(H,14,17)(H,15,18)	JKBMBCWPSBVPJZ-UHFFFAOYSA-N	88632	3-(2-Oxoazepan-3-yl)-1H-imidazo[4,5-b]pyridin-2-one::US20250388593, Example 201-2	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88632	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88632&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1489154	252660299							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127039	Cc1ccc(NC(=O)NCCCn2c(=O)n(C3CCCC(=O)NC3=O)c3ccccc32)cc1Cl	InChI=1S/C24H26ClN5O4/c1-15-10-11-16(14-17(15)25)27-23(33)26-12-5-13-29-18-6-2-3-7-19(18)30(24(29)34)20-8-4-9-21(31)28-22(20)32/h2-3,6-7,10-11,14,20H,4-5,8-9,12-13H2,1H3,(H2,26,27,33)(H,28,31,32)	ZHMREHCWAHCJMK-UHFFFAOYSA-N	88633	US20250388593, Example 202	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88633	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88633&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2161746	252660300							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127040	Cc1cc(NC(=O)NCCn2c(=O)n(C3CCCC(=O)NC3=O)c3ccccc32)ccc1Cl	InChI=1S/C23H24ClN5O4/c1-14-13-15(9-10-16(14)24)26-22(32)25-11-12-28-17-5-2-3-6-18(17)29(23(28)33)19-7-4-8-20(30)27-21(19)31/h2-3,5-6,9-10,13,19H,4,7-8,11-12H2,1H3,(H2,25,26,32)(H,27,30,31)	UZRWHBWJPOPJLN-UHFFFAOYSA-N	88634	US20250388593, Example 203	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88634	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88634&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2126229	252660301							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127041	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(C#CCCCCCC(=O)OC(C)(C)C)c21	InChI=1S/C26H33N3O5/c1-26(2,3)34-22(31)17-9-7-5-6-8-12-18-13-10-14-19-23(18)28(4)25(33)29(19)20-15-11-16-21(30)27-24(20)32/h10,13-14,20H,5-7,9,11,15-17H2,1-4H3,(H,27,30,32)	FMPBXMHJXLIWJM-UHFFFAOYSA-N	88635	tert-Butyl 8-[1-(2,7-dioxoazepan-3-yl)-3-methyl-2-oxobenzimidazol-4-yl]oct-7-ynoate::US20250388593, Example 206	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88635	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88635&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2492526	252660302							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127042	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(CCCCCCCC(=O)OC(C)(C)C)c21	InChI=1S/C26H37N3O5/c1-26(2,3)34-22(31)17-9-7-5-6-8-12-18-13-10-14-19-23(18)28(4)25(33)29(19)20-15-11-16-21(30)27-24(20)32/h10,13-14,20H,5-9,11-12,15-17H2,1-4H3,(H,27,30,32)	GMMREYYISVKAKQ-UHFFFAOYSA-N	88636	US20250388593, Example 207	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88636	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88636&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2347668	252660303							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127043	O=C(O)CCCCCCCc1nn(C2CCCC(=O)NC2=O)c2ccccc12	InChI=1S/C21H27N3O4/c25-19-13-8-12-18(21(28)22-19)24-17-11-7-6-9-15(17)16(23-24)10-4-2-1-3-5-14-20(26)27/h6-7,9,11,18H,1-5,8,10,12-14H2,(H,26,27)(H,22,25,28)	WELWTLFSJDLNKE-UHFFFAOYSA-N	88637	US20250388593, Example 209	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88637	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88637&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1183197	252660304							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127044	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(I)c21	InChI=1S/C14H14IN3O3/c1-17-12-8(15)4-2-5-9(12)18(14(17)21)10-6-3-7-11(19)16-13(10)20/h2,4-5,10H,3,6-7H2,1H3,(H,16,19,20)	UVRIXAXPLOQUCH-UHFFFAOYSA-N	88638	US20250388593, Example 210	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88638	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88638&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2358776	252660305							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127045	Cn1c(=O)n([C@@H]2CCCC(=O)NC2=O)c2cccc(I)c21	InChI=1S/C14H14IN3O3/c1-17-12-8(15)4-2-5-9(12)18(14(17)21)10-6-3-7-11(19)16-13(10)20/h2,4-5,10H,3,6-7H2,1H3,(H,16,19,20)	UVRIXAXPLOQUCH-UHFFFAOYSA-N	88639	US20250388593, Example 211	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88639	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88639&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4884316	252660306							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127046	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(CCC(=O)OC(C)(C)C)c21	InChI=1S/C21H27N3O5/c1-21(2,3)29-17(26)12-11-13-7-5-8-14-18(13)23(4)20(28)24(14)15-9-6-10-16(25)22-19(15)27/h5,7-8,15H,6,9-12H2,1-4H3,(H,22,25,27)	YFMYPKWDAAKLOK-UHFFFAOYSA-N	88640	US20250388593, Example 213	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88640	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88640&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			16196854	252660307							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127047	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(CCCCC(=O)OC(C)(C)C)c21	InChI=1S/C23H31N3O5/c1-23(2,3)31-19(28)14-6-5-9-15-10-7-11-16-20(15)25(4)22(30)26(16)17-12-8-13-18(27)24-21(17)29/h7,10-11,17H,5-6,8-9,12-14H2,1-4H3,(H,24,27,29)	DSMLRTCVSBPJTE-UHFFFAOYSA-N	88641	US20250388593, Example 214	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88641	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88641&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2442137	252660308							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127048	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(C#CCCCCCC(=O)OC(C)(C)C)cc21	InChI=1S/C26H33N3O5/c1-26(2,3)34-23(31)14-9-7-5-6-8-11-18-15-16-19-21(17-18)28(4)25(33)29(19)20-12-10-13-22(30)27-24(20)32/h15-17,20H,5-7,9-10,12-14H2,1-4H3,(H,27,30,32)	PATVSAKEELVHBO-UHFFFAOYSA-N	88642	US20250388593, Example 215	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88642	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88642&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3706223	252660309							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127049	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(CCCCCCCC(=O)OC(C)(C)C)cc21	InChI=1S/C26H37N3O5/c1-26(2,3)34-23(31)14-9-7-5-6-8-11-18-15-16-19-21(17-18)28(4)25(33)29(19)20-12-10-13-22(30)27-24(20)32/h15-17,20H,5-14H2,1-4H3,(H,27,30,32)	AWUXGNWQMCKSFH-UHFFFAOYSA-N	88643	US20250388593, Example 216	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88643	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88643&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1831123	242053816							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127050	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(CCCCC(=O)OC(C)(C)C)cc21	InChI=1S/C23H31N3O5/c1-23(2,3)31-20(28)11-6-5-8-15-12-13-16-18(14-15)25(4)22(30)26(16)17-9-7-10-19(27)24-21(17)29/h12-14,17H,5-11H2,1-4H3,(H,24,27,29)	ILXVOACYTGKRNW-UHFFFAOYSA-N	88644	US20250388593, Example 217	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88644	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88644&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5586260	252660310							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127051	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc21	InChI=1S/C24H32N4O5/c1-24(2,3)33-23(32)27-12-10-15(11-13-27)16-8-9-17-19(14-16)26(4)22(31)28(17)18-6-5-7-20(29)25-21(18)30/h8-9,14-15,18H,5-7,10-13H2,1-4H3,(H,25,29,30)	TUGYNVKDXZIADZ-UHFFFAOYSA-N	88645	US20250388593, Example 218	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88645	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88645&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2410031	252660311							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127052	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(C3CCN(CC(=O)OC(C)(C)C)CC3)cc21	InChI=1S/C25H34N4O5/c1-25(2,3)34-22(31)15-28-12-10-16(11-13-28)17-8-9-18-20(14-17)27(4)24(33)29(18)19-6-5-7-21(30)26-23(19)32/h8-9,14,16,19H,5-7,10-13,15H2,1-4H3,(H,26,30,32)	OJQDZJWQQFRSRX-UHFFFAOYSA-N	88646	US20250388593, Example 219	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88646	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88646&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			16745784	252660312							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127053	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(C3=CCN(C(=O)OC(C)(C)C)CC3)c21	InChI=1S/C24H30N4O5/c1-24(2,3)33-23(32)27-13-11-15(12-14-27)16-7-5-8-17-20(16)26(4)22(31)28(17)18-9-6-10-19(29)25-21(18)30/h5,7-8,11,18H,6,9-10,12-14H2,1-4H3,(H,25,29,30)	BSYPHYPDQCQAGM-UHFFFAOYSA-N	88682	tert-Butyl 4-[1-(2,7-dioxoazepan-3-yl)-3-methyl-2-oxobenzimidazol-4-yl]-3,6-dihydro-2H-pyridine-1-carboxylate (Example Compound 220)::US20250388593, Example 220	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88682	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88682&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			21773133	252660318							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127054	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(-c3ccncc3)c21	InChI=1S/C19H18N4O3/c1-22-17-13(12-8-10-20-11-9-12)4-2-5-14(17)23(19(22)26)15-6-3-7-16(24)21-18(15)25/h2,4-5,8-11,15H,3,6-7H2,1H3,(H,21,24,25)	MCIXWACKLGPFFR-UHFFFAOYSA-N	95468	3-[3-Methyl-2-oxo-4-(4-pyridyl) benzimidazol-1-yl]azepane-2,7-dione::US20250388593, Example 221	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95468	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95468&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			651074	164036712							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127055	Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(C3=CCN(CC(=O)OC(C)(C)C)CC3)c21	InChI=1S/C25H32N4O5/c1-25(2,3)34-21(31)15-28-13-11-16(12-14-28)17-7-5-8-18-22(17)27(4)24(33)29(18)19-9-6-10-20(30)26-23(19)32/h5,7-8,11,19H,6,9-10,12-15H2,1-4H3,(H,26,30,32)	SHHRXPFFPZUKDJ-UHFFFAOYSA-N	95469	US20250388593, Example 222	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95469	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95469&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			665128	164036713							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127056	CC(C)(C)OC(=O)c1ccc(N2CC[C@]3(CCCC(=O)NC3=O)CC2=O)cc1	InChI=1S/C21H26N2O5/c1-20(2,3)28-18(26)14-6-8-15(9-7-14)23-12-11-21(13-17(23)25)10-4-5-16(24)22-19(21)27/h6-9H,4-5,10-13H2,1-3H3,(H,22,24,27)	ONWGEIMUOXTXBN-UHFFFAOYSA-N	95470	tert-Butyl 4-(4,7,9-trioxo-3,8-diazaspiro [5.6]dodecan-3-yl) benzoate (Optically Active A, Example Compound 223) and (Optically Active B, Example Compound 224)::US20250388593, Example 223	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95470	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95470&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			665749	164036714							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127057	CC(C)(C)OC(=O)c1ccc(N2CC[C@@]3(CCCC(=O)NC3=O)CC2=O)cc1	InChI=1S/C21H26N2O5/c1-20(2,3)28-18(26)14-6-8-15(9-7-14)23-12-11-21(13-17(23)25)10-4-5-16(24)22-19(21)27/h6-9H,4-5,10-13H2,1-3H3,(H,22,24,27)	ONWGEIMUOXTXBN-UHFFFAOYSA-N	95472	US20250388593, Example 224	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95472	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95472&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3237652	164036716							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127058	O=C1CCCC2(CCN(c3ccc([N+](=O)[O-])cc3)C(=O)C2)C(=O)N1	InChI=1S/C16H17N3O5/c20-13-2-1-7-16(15(22)17-13)8-9-18(14(21)10-16)11-3-5-12(6-4-11)19(23)24/h3-6H,1-2,7-10H2,(H,17,20,22)	QIRXHAXMJXHBLM-UHFFFAOYSA-N	95473	3-(4-Nitrophenyl)-3,8-diazaspiro [5.6]dodecane-4,7,9-trione ::US20250388593, Example 225	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95473	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95473&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3241786	164036717							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127059	Nc1ccc(N2CCC3(CCCC(=O)NC3=O)CC2=O)cc1	InChI=1S/C16H19N3O3/c17-11-3-5-12(6-4-11)19-9-8-16(10-14(19)21)7-1-2-13(20)18-15(16)22/h3-6H,1-2,7-10,17H2,(H,18,20,22)	NGACSVFEJOSCGC-UHFFFAOYSA-N	95474	US20250388593, Example 228	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95474	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95474&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3245185	164036718							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127060	CC(C)(C)OC(=O)CCCCCN1CC2(CC(=O)N(C3CCC(=O)NC3=O)C2=O)C1	InChI=1S/C21H31N3O6/c1-20(2,3)30-17(27)7-5-4-6-10-23-12-21(13-23)11-16(26)24(19(21)29)14-8-9-15(25)22-18(14)28/h14H,4-13H2,1-3H3,(H,22,25,28)	DUCBXEHTNWZZPZ-UHFFFAOYSA-N	95475	US20250388593, Example 229	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95475	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95475&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2162790	164036719							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127061	Nc1nccc(N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)n1	InChI=1S/C15H16N6O4/c16-14-17-4-3-9(18-14)20-6-15(7-20)5-11(23)21(13(15)25)8-1-2-10(22)19-12(8)24/h3-4,8H,1-2,5-7H2,(H2,16,17,18)(H,19,22,24)	MXNVZOFEGIQCHN-UHFFFAOYSA-N	95476	US20250388593, Example 230	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95476	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95476&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1091676	164036720							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127062	CC(C)(C)OC(=O)c1ccc2nc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)sc2c1	InChI=1S/C23H24N4O6S/c1-22(2,3)33-19(31)12-4-5-13-15(8-12)34-21(24-13)26-10-23(11-26)9-17(29)27(20(23)32)14-6-7-16(28)25-18(14)30/h4-5,8,14H,6-7,9-11H2,1-3H3,(H,25,28,30)	NAQASMAOVZPDFN-UHFFFAOYSA-N	95477	US20250388593, Example 231	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95477	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95477&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1954059	164036721							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127063	O=C4CCC(N3C(=O)CC2(CN(c1ccc([N+](=O)[O-])cc1)C2)C3=O)C(=O)N4	InChI=1S/C17H16N4O6/c22-13-6-5-12(15(24)18-13)20-14(23)7-17(16(20)25)8-19(9-17)10-1-3-11(4-2-10)21(26)27/h1-4,12H,5-9H2,(H-,18,22,24,26,27)/p+1	IQBPAMZIWKTBMK-UHFFFAOYSA-O	95478	US20250388593, Example 232	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95478	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95478&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5294436	164036722							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127079	CC(C)(C)OC(=O)NCCCNc1nccc(N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)n1	InChI=1S/C23H31N7O6/c1-22(2,3)36-21(35)26-9-4-8-24-20-25-10-7-15(27-20)29-12-23(13-29)11-17(32)30(19(23)34)14-5-6-16(31)28-18(14)33/h7,10,14H,4-6,8-9,11-13H2,1-3H3,(H,26,35)(H,24,25,27)(H,28,31,33)	RUIOYQIVFYCFRJ-UHFFFAOYSA-N	95479	US20250388593, Example 233	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95479	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95479&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			969014	164036723							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127080	CC(C)(C)OC(=O)COCCNc1nccc(N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)n1	InChI=1S/C23H30N6O7/c1-22(2,3)36-18(32)11-35-9-8-25-21-24-7-6-15(26-21)28-12-23(13-28)10-17(31)29(20(23)34)14-4-5-16(30)27-19(14)33/h6-7,14H,4-5,8-13H2,1-3H3,(H,24,25,26)(H,27,30,33)	KTDIYZDVHPRURD-UHFFFAOYSA-N	95480	US20250388593, Example 234	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95480	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95480&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			857537	164036724							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127082	Cn1ccc2c(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)ncnc21	InChI=1S/C18H18N6O4/c1-22-5-4-10-14(22)19-9-20-15(10)23-7-18(8-23)6-13(26)24(17(18)28)11-2-3-12(25)21-16(11)27/h4-5,9,11H,2-3,6-8H2,1H3,(H,21,25,27)	BUKOBNSXQCUWHI-UHFFFAOYSA-N	95481	US20250388593, Example 235	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95481	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95481&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3228813	164036725							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127083	CC(C)(C)OC(=O)NCCCCCCCCn1ccc2c(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)ncnc21	InChI=1S/C30H41N7O6/c1-29(2,3)43-28(42)31-13-8-6-4-5-7-9-14-35-15-12-20-24(35)32-19-33-25(20)36-17-30(18-36)16-23(39)37(27(30)41)21-10-11-22(38)34-26(21)40/h12,15,19,21H,4-11,13-14,16-18H2,1-3H3,(H,31,42)(H,34,38,40)	TZWSCMSQKORQGQ-UHFFFAOYSA-N	95482	US20250388593, Example 236	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95482	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95482&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			935238	164036726							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127084	CC(C)(C)OC(=O)N1CCC(Oc2ccc(CN3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)cc2)CC1	InChI=1S/C28H36N4O7/c1-27(2,3)39-26(37)31-12-10-20(11-13-31)38-19-6-4-18(5-7-19)15-30-16-28(17-30)14-23(34)32(25(28)36)21-8-9-22(33)29-24(21)35/h4-7,20-21H,8-17H2,1-3H3,(H,29,33,35)	ZZVUMBBQNNZODP-UHFFFAOYSA-N	95483	US20250388593, Example 237	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95483	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95483&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			9550774	164036727							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127087	COc1ccc2nc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)sc2c1	InChI=1S/C19H18N4O5S/c1-28-10-2-3-11-13(6-10)29-18(20-11)22-8-19(9-22)7-15(25)23(17(19)27)12-4-5-14(24)21-16(12)26/h2-3,6,12H,4-5,7-9H2,1H3,(H,21,24,26)	NPDBLLBHCKUWAF-UHFFFAOYSA-N	95484	US20250388593, Example 238	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95484	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95484&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1545968	164036728							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127088	COc1ccc2sc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)nc2c1	InChI=1S/C19H18N4O5S/c1-28-10-2-4-13-11(6-10)20-18(29-13)22-8-19(9-22)7-15(25)23(17(19)27)12-3-5-14(24)21-16(12)26/h2,4,6,12H,3,5,7-9H2,1H3,(H,21,24,26)	QLHJILSADHLGTG-UHFFFAOYSA-N	95485	US20250388593, Example 239	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95485	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95485&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4279549	164036729							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127089	COc1cccc2sc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)nc12	InChI=1S/C19H18N4O5S/c1-28-11-3-2-4-12-15(11)21-18(29-12)22-8-19(9-22)7-14(25)23(17(19)27)10-5-6-13(24)20-16(10)26/h2-4,10H,5-9H2,1H3,(H,20,24,26)	PGZWFIGQYBWMLV-UHFFFAOYSA-N	95486	US20250388593, Example 240	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95486	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95486&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5243996	164036730							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127090	CC(C)(C)OC(=O)NCCCCCOc1ccc2nc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)sc2c1	InChI=1S/C28H35N5O7S/c1-27(2,3)40-26(38)29-11-5-4-6-12-39-17-7-8-18-20(13-17)41-25(30-18)32-15-28(16-32)14-22(35)33(24(28)37)19-9-10-21(34)31-23(19)36/h7-8,13,19H,4-6,9-12,14-16H2,1-3H3,(H,29,38)(H,31,34,36)	HXMGLVGEFCVVQD-UHFFFAOYSA-N	95487	US20250388593, Example 241	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95487	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95487&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			9551986	164036731							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127091	CC(C)(C)OC(=O)N1CCc2c(ncnc2N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)C1	InChI=1S/C23H28N6O6/c1-22(2,3)35-21(34)27-7-6-13-14(9-27)24-12-25-18(13)28-10-23(11-28)8-17(31)29(20(23)33)15-4-5-16(30)26-19(15)32/h12,15H,4-11H2,1-3H3,(H,26,30,32)	SUYXZCICQNEHMU-UHFFFAOYSA-N	95488	US20250388593, Example 242	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95488	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95488&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5346844	164036732							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127092	CC(C)(C)OC(=O)c1ccc(C2(F)CCCC(=O)NC2=O)cc1	InChI=1S/C17H20FNO4/c1-16(2,3)23-14(21)11-6-8-12(9-7-11)17(18)10-4-5-13(20)19-15(17)22/h6-9H,4-5,10H2,1-3H3,(H,19,20,22)	WRHMYIYDNIUQNU-UHFFFAOYSA-N	95489	tert-Butyl 4-(3-fluoro-2,7-dioxoazepan-3-yl) benzoate::US20250388593, Example 243	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95489	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95489&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3220834	164036733							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127093	CC(=O)NC1=CC(C2(F)CCCC(=O)NC2=O)CC=C1	InChI=1S/C14H17FN2O3/c1-9(18)16-11-5-2-4-10(8-11)14(15)7-3-6-12(19)17-13(14)20/h2,5,8,10H,3-4,6-7H2,1H3,(H,16,18)(H,17,19,20)	OHLHUJXMCBWYTP-UHFFFAOYSA-N	95490	N-[3-(3-Fluoro-2,7-dioxoazepan-3-yl) phenyl]acetamide::US20250388593, Example 245	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95490	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95490&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6874331	164036734							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127094	O=C1CCCC(n2nc(-c3ccccc3)ccc2=O)C(=O)N1	InChI=1S/C16H15N3O3/c20-14-8-4-7-13(16(22)17-14)19-15(21)10-9-12(18-19)11-5-2-1-3-6-11/h1-3,5-6,9-10,13H,4,7-8H2,(H,17,20,22)	NGWNRNXNZRBQCW-UHFFFAOYSA-N	95491	3-(6-Oxo-3-phenylpyridazin-1-yl) azepane-2,7-dione::US20250388593, Example 246	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95491	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95491&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			786590	164036735							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127095	O=C1CCCC(n2ncc(-c3ccccc3)cc2=O)C(=O)N1	InChI=1S/C16H15N3O3/c20-14-8-4-7-13(16(22)18-14)19-15(21)9-12(10-17-19)11-5-2-1-3-6-11/h1-3,5-6,9-10,13H,4,7-8H2,(H,18,20,22)	MBAZGAYGMKQCDL-UHFFFAOYSA-N	95492	US20250388593, Example 247	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95492	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95492&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1287749	164036736							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127096	O=C1CCCC(n2ncc(Cl)cc2=O)C(=O)N1	InChI=1S/C10H10ClN3O3/c11-6-4-9(16)14(12-5-6)7-2-1-3-8(15)13-10(7)17/h4-5,7H,1-3H2,(H,13,15,17)	OKJFJUWPAJZTFB-UHFFFAOYSA-N	95493	US20250388593, Example 248	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95493	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95493&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5346576	164036737							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127099	O=C1CCCC(n2nnc3ccccc32)C(=O)N1	InChI=1S/C12H12N4O2/c17-11-7-3-6-10(12(18)13-11)16-9-5-2-1-4-8(9)14-15-16/h1-2,4-5,10H,3,6-7H2,(H,13,17,18)	QCKJOQJKNQHMOW-UHFFFAOYSA-N	95494	US20250388593, Example 250	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95494	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95494&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5346805	164036738							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127100	COc1ccc2nn(C3CCCC(=O)NC3=O)nc2c1	InChI=1S/C13H14N4O3/c1-20-8-5-6-9-10(7-8)16-17(15-9)11-3-2-4-12(18)14-13(11)19/h5-7,11H,2-4H2,1H3,(H,14,18,19)	BOPCJGGHCFNZDD-UHFFFAOYSA-N	95495	US20250388593, Example 251	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95495	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95495&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5346839	164036739							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127102	O=C1CCCC(n2nc(Cl)ccc2=O)C(=O)N1	InChI=1S/C10H10ClN3O3/c11-7-4-5-9(16)14(13-7)6-2-1-3-8(15)12-10(6)17/h4-6H,1-3H2,(H,12,15,17)	RKYVQDBBURUIST-UHFFFAOYSA-N	95496	US20250388593, Example 252	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95496	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95496&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5346668	164036740							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127104	COc1ccc2c(c1)nnn2C1CCCC(=O)NC1=O	InChI=1S/C13H14N4O3/c1-20-8-5-6-10-9(7-8)15-16-17(10)11-3-2-4-12(18)14-13(11)19/h5-7,11H,2-4H2,1H3,(H,14,18,19)	QWMQWTOZHUPYFG-UHFFFAOYSA-N	95497	US20250388593, Example 253	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95497	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95497&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3140303	164036741							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
127105	COc1ccc2nnn(C3CCCC(=O)NC3=O)c2c1	InChI=1S/C13H14N4O3/c1-20-8-5-6-9-11(7-8)17(16-15-9)10-3-2-4-12(18)14-13(10)19/h5-7,10H,2-4H2,1H3,(H,14,18,19)	CPLQSRRRDBTXNP-UHFFFAOYSA-N	95498	US20250388593, Example 254	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95498	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95498&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6878016	164036742							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129305	COc1cccc2c1nnn2C1CCCC(=O)NC1=O	InChI=1S/C13H14N4O3/c1-20-10-6-2-4-8-12(10)15-16-17(8)9-5-3-7-11(18)14-13(9)19/h2,4,6,9H,3,5,7H2,1H3,(H,14,18,19)	ZTVLMPMJFYBEGP-UHFFFAOYSA-N	95499	US20250388593, Example 255	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95499	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95499&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5239604	164036743							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129306	COc1cccc2nn(C3CCCC(=O)NC3=O)nc12	InChI=1S/C13H14N4O3/c1-20-10-6-2-4-8-12(10)16-17(15-8)9-5-3-7-11(18)14-13(9)19/h2,4,6,9H,3,5,7H2,1H3,(H,14,18,19)	DDULZFDLEJMGBM-UHFFFAOYSA-N	95500	US20250388593, Example 256	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95500	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95500&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4226646	164036744							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129307	O=C1CCCC(n2c(=O)ccc3cc(Br)ccc32)C(=O)N1	InChI=1S/C15H13BrN2O3/c16-10-5-6-11-9(8-10)4-7-14(20)18(11)12-2-1-3-13(19)17-15(12)21/h4-8,12H,1-3H2,(H,17,19,21)	ISVFCMFQWPVAGC-UHFFFAOYSA-N	95501	US20250388593, Example 257	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95501	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95501&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4106879	164036745							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129308	COc1cccc2c1ccc(=O)n2C1CCCC(=O)NC1=O	InChI=1S/C16H16N2O4/c1-22-13-6-2-4-11-10(13)8-9-15(20)18(11)12-5-3-7-14(19)17-16(12)21/h2,4,6,8-9,12H,3,5,7H2,1H3,(H,17,19,21)	KPTRPGNUEPFWLJ-UHFFFAOYSA-N	95502	US20250388593, Example 258	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95502	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95502&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3882803	164036746							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129309	Cn1c(=O)c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21	InChI=1S/C15H15N3O4/c1-17-9-5-2-3-6-10(9)18(15(22)14(17)21)11-7-4-8-12(19)16-13(11)20/h2-3,5-6,11H,4,7-8H2,1H3,(H,16,19,20)	LNCHQFMAEKDRMG-UHFFFAOYSA-N	95503	US20250388593, Example 259	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95503&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5228434	164036747							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129310	CC(C)(C)OC(=O)CCc1ccc2c(c1)oc(=O)n2C1CCCC(=O)NC1=O	InChI=1S/C20H24N2O6/c1-20(2,3)28-17(24)10-8-12-7-9-13-15(11-12)27-19(26)22(13)14-5-4-6-16(23)21-18(14)25/h7,9,11,14H,4-6,8,10H2,1-3H3,(H,21,23,25)	RMNWYELGEZFSGU-UHFFFAOYSA-N	95504	US20250388593, Example 260	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95504	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95504&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			133081082	164036748							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129311	Cn1c(=O)n(C2CCCC(=O)NC2=O)c(=O)c2ccc(Br)cc21	InChI=1S/C15H14BrN3O4/c1-18-11-7-8(16)5-6-9(11)14(22)19(15(18)23)10-3-2-4-12(20)17-13(10)21/h5-7,10H,2-4H2,1H3,(H,17,20,21)	HYZQEFYRTNOMKO-UHFFFAOYSA-N	95505	US20250388593, Example 261	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95505	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95505&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2466717	164036749							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129312	CC(C)(C)OC(=O)CCc1ccc2c(c1)sc(=O)n2C1CCCC(=O)NC1=O	InChI=1S/C20H24N2O5S/c1-20(2,3)27-17(24)10-8-12-7-9-13-15(11-12)28-19(26)22(13)14-5-4-6-16(23)21-18(14)25/h7,9,11,14H,4-6,8,10H2,1-3H3,(H,21,23,25)	QJRHKWWEQRSGEL-UHFFFAOYSA-N	95506	US20250388593, Example 262	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95506	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95506&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4389752	164036750							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129313	CC(C)(C)OC(=O)CCc1cccc2c(=O)n(C3CCCC(=O)NC3=O)ccc12	InChI=1S/C22H26N2O5/c1-22(2,3)29-19(26)11-10-14-6-4-7-16-15(14)12-13-24(21(16)28)17-8-5-9-18(25)23-20(17)27/h4,6-7,12-13,17H,5,8-11H2,1-3H3,(H,23,25,27)	MCKLUUOOWVOSIE-UHFFFAOYSA-N	95507	US20250388593, Example 263	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95507	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95507&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			11840881	164036751							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129314	Cn1c(=O)n(C2CCCC(=O)NC2=O)c(=O)c2ccc(CCC(=O)OC(C)(C)C)cc21	InChI=1S/C22H27N3O6/c1-22(2,3)31-18(27)11-9-13-8-10-14-16(12-13)24(4)21(30)25(20(14)29)15-6-5-7-17(26)23-19(15)28/h8,10,12,15H,5-7,9,11H2,1-4H3,(H,23,26,28)	BZOBNTLDANKYAF-UHFFFAOYSA-N	95508	US20250388593, Example 265	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95508	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95508&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2929455	164036752							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129315	Cn1c(-c2ccc(CCC(=O)OC(C)(C)C)cc2)nn(C2CCCC(=O)NC2=O)c1=O	InChI=1S/C22H28N4O5/c1-22(2,3)31-18(28)13-10-14-8-11-15(12-9-14)19-24-26(21(30)25(19)4)16-6-5-7-17(27)23-20(16)29/h8-9,11-12,16H,5-7,10,13H2,1-4H3,(H,23,27,29)	NBRIHPPXKZTBQW-UHFFFAOYSA-N	95509	US20250388593, Example 266	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95509	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95509&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4338403	164036753							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129316	O=C1CCCC(Oc2ccc(Br)cc2)C(=O)N1	InChI=1S/C12H12BrNO3/c13-8-4-6-9(7-5-8)17-10-2-1-3-11(15)14-12(10)16/h4-7,10H,1-3H2,(H,14,15,16)	CMBNXMXJMUVAJK-UHFFFAOYSA-N	95510	US20250388593, Example 267	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95510	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95510&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			994072	164036754							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129317	CC(C)(C)OC(=O)c1ccc(OC2CCCC(=O)NC2)nc1	InChI=1S/C16H22N2O4/c1-16(2,3)22-15(20)11-7-8-14(18-9-11)21-12-5-4-6-13(19)17-10-12/h7-9,12H,4-6,10H2,1-3H3,(H,17,19)	FGRZLIWTDLTZKV-UHFFFAOYSA-N	95511	tert-Butyl 6-(7-oxoazepan-3-yl) oxypyridine-3-carboxylate ::US20250388593, Example 268	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95511	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95511&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4267803	164036755							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129318	O=C1CCCC2(CCN(C(=O)C3CCN(c4ncccn4)CC3)C2)C(=O)N1	InChI=1S/C19H25N5O3/c25-15-3-1-6-19(17(27)22-15)7-12-24(13-19)16(26)14-4-10-23(11-5-14)18-20-8-2-9-21-18/h2,8-9,14H,1,3-7,10-13H2,(H,22,25,27)	LEWYZAZSRZANQO-UHFFFAOYSA-N	95512	US20250388593, Example 269	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95512	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95512&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3966103	164036756							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129319	CN(C1CCCC(=O)NC1=O)S(=O)(=O)c1ccc(CCCCCCNC(=O)OC(C)(C)C)cc1	InChI=1S/C24H37N3O6S/c1-24(2,3)33-23(30)25-17-8-6-5-7-10-18-13-15-19(16-14-18)34(31,32)27(4)20-11-9-12-21(28)26-22(20)29/h13-16,20H,5-12,17H2,1-4H3,(H,25,30)(H,26,28,29)	ZAZROKMHGVRKPP-UHFFFAOYSA-N	95513	US20250388593, Example 271	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95513	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95513&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2215518	164036757							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129320	CN1CCN(c2cnn(C3CCCC(=O)NC3=O)c(=O)c2)CC1	InChI=1S/C15H21N5O3/c1-18-5-7-19(8-6-18)11-9-14(22)20(16-10-11)12-3-2-4-13(21)17-15(12)23/h9-10,12H,2-8H2,1H3,(H,17,21,23)	PZKLKQUUJNQSKV-UHFFFAOYSA-N	95514	US20250388593, Example 272	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95514&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1304231	164036758							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129321	CC(C)(C)OC(=O)N1CC2(CC(=O)N(C3CCCC(=O)NC3=O)C2=O)C1	InChI=1S/C17H23N3O6/c1-16(2,3)26-15(25)19-8-17(9-19)7-12(22)20(14(17)24)10-5-4-6-11(21)18-13(10)23/h10H,4-9H2,1-3H3,(H,18,21,23)	YIYRCDHIAJMYNH-UHFFFAOYSA-N	95515	US20250388593, Example 273-2	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95515	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95515&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1164709	164036759							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129322	O=C1CCCC(N2C(=O)OCC3=C2C=CC([N+](=O)[O-])C3)C(=O)N1	InChI=1S/C14H15N3O6/c18-12-3-1-2-11(13(19)15-12)16-10-5-4-9(17(21)22)6-8(10)7-23-14(16)20/h4-5,9,11H,1-3,6-7H2,(H,15,18,19)	KPSOMMQHIQZZIO-UHFFFAOYSA-N	95516	3-(6-Nitro-2-oxo-4H-3,1-benzoxazin-1-yl) azepane-2,7-dione ::US20250388593, Example 274	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95516&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			685884	164036760							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129323	CC(C)(C)OC(=O)Cn1c(=O)c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21	InChI=1S/C20H23N3O6/c1-20(2,3)29-16(25)11-22-12-7-4-5-8-13(12)23(19(28)18(22)27)14-9-6-10-15(24)21-17(14)26/h4-5,7-8,14H,6,9-11H2,1-3H3,(H,21,24,26)	YFGDGXOKMXCCGS-UHFFFAOYSA-N	95517	tert-Butyl 2-[4-(2,7-dioxoazepan-3-yl)-2,3-dioxoquinoxalin-1-yl]acetate::US20250388593, Example 275	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95517	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95517&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1448653	164036761							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129324	CC(C)(C)OC(=O)N1CCC(c2ccc(OC3CCCCNC3=O)cc2)CC1	InChI=1S/C22H32N2O4/c1-22(2,3)28-21(26)24-14-11-17(12-15-24)16-7-9-18(10-8-16)27-19-6-4-5-13-23-20(19)25/h7-10,17,19H,4-6,11-15H2,1-3H3,(H,23,25)	KXMUUPVYJJQRKQ-UHFFFAOYSA-N	95518	tert-Butyl 4-[4-(2-oxoazepan-3-yl) oxyphenyl]piperidine-1-carboxylate::US20250388593, Example 276	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95518&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4090590	164036762							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129325	O=C1CCC(N2C(=O)CC3(CN(C4CCN(CC(=O)OCc5ccccc5)CC4)C3)C2=O)C(=O)N1	InChI=1S/C25H30N4O6/c30-20-7-6-19(23(33)26-20)29-21(31)12-25(24(29)34)15-28(16-25)18-8-10-27(11-9-18)13-22(32)35-14-17-4-2-1-3-5-17/h1-5,18-19H,6-16H2,(H,26,30,33)	CDXJJHQFUNITCJ-UHFFFAOYSA-N	95519	US20250388593, Example 277	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95519	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95519&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5191161	164036763							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129326	CC(C)(C)OC(=O)NCCc1ccc(S(=O)(=O)N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)cc1	InChI=1S/C24H30N4O8S/c1-23(2,3)36-22(33)25-11-10-15-4-6-16(7-5-15)37(34,35)27-13-24(14-27)12-19(30)28(21(24)32)17-8-9-18(29)26-20(17)31/h4-7,17H,8-14H2,1-3H3,(H,25,33)(H,26,29,31)	RZPYXTZWZXDZKT-UHFFFAOYSA-N	95520	US20250388593, Example 278	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95520&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1186121	164036764							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129327	CN(C1CCCC(=O)NC1=O)S(=O)(=O)c1ccc(CCCCC(=O)OC(C)(C)C)cc1	InChI=1S/C22H32N2O6S/c1-22(2,3)30-20(26)11-6-5-8-16-12-14-17(15-13-16)31(28,29)24(4)18-9-7-10-19(25)23-21(18)27/h12-15,18H,5-11H2,1-4H3,(H,23,25,27)	NTMGEMKILSHXFL-UHFFFAOYSA-N	95521	tert-Butyl 5-[4-[(2,7-dioxoazepan-3-yl)-methylsulfamoyl]phenyl]pentanoate::US20250388593, Example 279	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95521	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95521&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			46496113	164036765							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129328	Cn1nc(N2CC=CC(=O)NC2=O)c2ccc(Br)cc21	InChI=1S/C13H11BrN4O2/c1-17-10-7-8(14)4-5-9(10)12(16-17)18-6-2-3-11(19)15-13(18)20/h2-5,7H,6H2,1H3,(H,15,19,20)	GNPVNYNRDPEOAV-UHFFFAOYSA-N	95522	US20250388593, Example 281	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95522&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5053814	164036766							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129329	Cn1nc(N2CC=CC(=O)NC2=O)c2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc21	InChI=1S/C23H29N5O4/c1-23(2,3)32-22(31)27-12-9-15(10-13-27)16-7-8-17-18(14-16)26(4)25-20(17)28-11-5-6-19(29)24-21(28)30/h5-8,14-15H,9-13H2,1-4H3,(H,24,29,30)	SGKGYFVJJQTXNA-UHFFFAOYSA-N	95523	US20250388593, Example 282	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95523	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95523&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2397695	164036767							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129330	CC1(N2CC=CC(=O)NC2=O)C(=O)N(CC(=O)OCc2ccccc2)c2ccccc21	InChI=1S/C23H21N3O5/c1-23(26-13-7-12-19(27)24-22(26)30)17-10-5-6-11-18(17)25(21(23)29)14-20(28)31-15-16-8-3-2-4-9-16/h2-12H,13-15H2,1H3,(H,24,27,30)	PKOKNMCPPLAELA-UHFFFAOYSA-N	95524	US20250388593, Example 283	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95524&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2127262	164036768							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129331	Cn1nc(N2C=CCC(=O)NC2=O)c2ccc(/C=C/C(=O)OC(C)(C)C)cc21	InChI=1S/C20H22N4O4/c1-20(2,3)28-17(26)10-8-13-7-9-14-15(12-13)23(4)22-18(14)24-11-5-6-16(25)21-19(24)27/h5,7-12H,6H2,1-4H3,(H,21,25,27)	PSEHPWMLVKECDN-UHFFFAOYSA-N	95525	US20250388593, Example 287	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95525&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2342756	164036769							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129332	CN1C(=O)C(C)(N2C=CCC(=O)NC2=O)c2ccc(/C=C/C(=O)OC(C)(C)C)cc21	InChI=1S/C22H25N3O5/c1-21(2,3)30-18(27)11-9-14-8-10-15-16(13-14)24(5)19(28)22(15,4)25-12-6-7-17(26)23-20(25)29/h6,8-13H,7H2,1-5H3,(H,23,26,29)	AHUSEVJLQNTMSS-UHFFFAOYSA-N	95526	US20250388593, Example 288	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95526	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95526&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2522096	164036770							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129333	CN1C(=O)C(C)(N2C=CCC(=O)NC2=O)c2cccc(/C=C/C(=O)OC(C)(C)C)c21	InChI=1S/C22H25N3O5/c1-21(2,3)30-17(27)12-11-14-8-6-9-15-18(14)24(5)19(28)22(15,4)25-13-7-10-16(26)23-20(25)29/h6-9,11-13H,10H2,1-5H3,(H,23,26,29)	DVILLNUYBTXVRA-UHFFFAOYSA-N	95527	US20250388593, Example 289	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95527	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95527&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2372624	164036771							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129334	CN1C(=O)[C@H](N2C=CCC(=O)NC2=O)C[C@H]1c1ccc(/C=C/C(=O)OC(C)(C)C)cc1	InChI=1S/C23H27N3O5/c1-23(2,3)31-20(28)12-9-15-7-10-16(11-8-15)17-14-18(21(29)25(17)4)26-13-5-6-19(27)24-22(26)30/h5,7-13,17-18H,6,14H2,1-4H3,(H,24,27,30)	VJWPRJLERPFZHI-UHFFFAOYSA-N	95528	US20250388593, Example 290	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95528	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95528&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2309197	164036772							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129335	Cn1nc(N2CCCC(=O)NC2=O)c2ccc(CCC(=O)OC(C)(C)C)cc21	InChI=1S/C20H26N4O4/c1-20(2,3)28-17(26)10-8-13-7-9-14-15(12-13)23(4)22-18(14)24-11-5-6-16(25)21-19(24)27/h7,9,12H,5-6,8,10-11H2,1-4H3,(H,21,25,27)	PKZNNCSCTGPTRQ-UHFFFAOYSA-N	95529	US20250388593, Example 291	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95529	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95529&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2475269	164036773							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129336	CC1(N2CCCC(=O)NC2=O)C(=O)N(CC(=O)O)c2ccccc21	InChI=1S/C16H17N3O5/c1-16(19-8-4-7-12(20)17-15(19)24)10-5-2-3-6-11(10)18(14(16)23)9-13(21)22/h2-3,5-6H,4,7-9H2,1H3,(H,21,22)(H,17,20,24)	JWRADJBLLZMALB-UHFFFAOYSA-N	95530	US20250388593, Example 292	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95530	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95530&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3648622	164036774							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129337	Cc1ccc(NC(=O)Nc2ccc3nc(N4CCC5(CCCC(=O)NC5=O)C4)sc3c2)cc1Cl	InChI=1S/C24H24ClN5O3S/c1-14-4-5-15(11-17(14)25)26-22(33)27-16-6-7-18-19(12-16)34-23(28-18)30-10-9-24(13-30)8-2-3-20(31)29-21(24)32/h4-7,11-12H,2-3,8-10,13H2,1H3,(H2,26,27,33)(H,29,31,32)	HXVFUHLXDBMFOS-UHFFFAOYSA-N	95531	US20250388593, Example 296	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95531	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95531&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3795763	164036775							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129338	Nc1ccc(N2CCC(N3CCCC(=O)NC3=O)C2=O)cc1	InChI=1S/C15H18N4O3/c16-10-3-5-11(6-4-10)18-9-7-12(14(18)21)19-8-1-2-13(20)17-15(19)22/h3-6,12H,1-2,7-9,16H2,(H,17,20,22)	XXPFHLQNMIJNFE-UHFFFAOYSA-N	95532	US20250388593, Example 297	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95532	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95532&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3370762	164036776							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129339	CC(C)(C)OC(=O)CCCCCNc1cccc(C2CCCC(=O)NC2=O)c1	InChI=1S/C22H32N2O4/c1-22(2,3)28-20(26)13-5-4-6-14-23-17-10-7-9-16(15-17)18-11-8-12-19(25)24-21(18)27/h7,9-10,15,18,23H,4-6,8,11-14H2,1-3H3,(H,24,25,27)	LYDZPZTVVXPIDS-UHFFFAOYSA-N	95533	US20250388593, Example 298	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95533	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95533&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			652603	164036777							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129340	CC(C)(C)OC(=O)CCCCCNc1ccc(C(=O)N2CCC3(CCCC(=O)NC3=O)C2)cc1	InChI=1S/C26H37N3O5/c1-25(2,3)34-22(31)9-5-4-6-16-27-20-12-10-19(11-13-20)23(32)29-17-15-26(18-29)14-7-8-21(30)28-24(26)33/h10-13,27H,4-9,14-18H2,1-3H3,(H,28,30,33)	BWRKEMZNCRCCPC-UHFFFAOYSA-N	95534	US20250388593, Example 300	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95534	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95534&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2112060	164036778							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129341	CC(C)(C)OC(=O)CCCCCNc1ccc(N2CCC3(CCCC(=O)NC3=O)CC2=O)cc1	InChI=1S/C26H37N3O5/c1-25(2,3)34-23(32)9-5-4-6-16-27-19-10-12-20(13-11-19)29-17-15-26(18-22(29)31)14-7-8-21(30)28-24(26)33/h10-13,27H,4-9,14-18H2,1-3H3,(H,28,30,33)	BIZNUXAVHYQRRJ-UHFFFAOYSA-N	95535	US20250388593, Example 301	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95535	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95535&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6877972	164036779							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129937	CC(C)(C)OC(=O)CCCCCNc1ccc(N2CCC(N3CCCC(=O)NC3=O)C2=O)cc1	InChI=1S/C25H36N4O5/c1-25(2,3)34-22(31)9-5-4-6-15-26-18-10-12-19(13-11-18)28-17-14-20(23(28)32)29-16-7-8-21(30)27-24(29)33/h10-13,20,26H,4-9,14-17H2,1-3H3,(H,27,30,33)	FAFLNGRXCVJQPG-UHFFFAOYSA-N	95536	US20250388593, Example 302	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95536	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95536&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5844273	164036780							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129938	CC(C)(C)OC(=O)NCCCCCCCNc1ccc2nc(N3CCCC(=O)NC3=O)sc2c1	InChI=1S/C24H35N5O4S/c1-24(2,3)33-23(32)26-14-8-6-4-5-7-13-25-17-11-12-18-19(16-17)34-22(27-18)29-15-9-10-20(30)28-21(29)31/h11-12,16,25H,4-10,13-15H2,1-3H3,(H,26,32)(H,28,30,31)	MWDBNCLOENVOAH-UHFFFAOYSA-N	95537	US20250388593, Example 303	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95537	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95537&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			9566277	164036781							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129939	CC(C)(C)OC(=O)NCCCCCCCNc1ccc(N2CCC3(CCCC(=O)NC3=O)CC2=O)cc1	InChI=1S/C28H42N4O5/c1-27(2,3)37-26(36)30-18-8-6-4-5-7-17-29-21-11-13-22(14-12-21)32-19-16-28(20-24(32)34)15-9-10-23(33)31-25(28)35/h11-14,29H,4-10,15-20H2,1-3H3,(H,30,36)(H,31,33,35)	XGBMMVCMYMLZQI-UHFFFAOYSA-N	95538	US20250388593, Example 304	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95538	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95538&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			9566278	164036782							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129940	CC(C)(C)[Si](C)(C)OC1c2cccc(Br)c2CC1N1CC=CC(=O)NC1=O	InChI=1S/C20H27BrN2O3Si/c1-20(2,3)27(4,5)26-18-13-8-6-9-15(21)14(13)12-16(18)23-11-7-10-17(24)22-19(23)25/h6-10,16,18H,11-12H2,1-5H3,(H,22,24,25)	XWVHGWPTQJGQIT-UHFFFAOYSA-N	95539	3-[4-Bromo-1-[tert-butyl(dimethyl)silyl]oxy-indan-2-yl]-4H-1,3-diazepine-2,7-dione::US20250388593, Example 307	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95539	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95539&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			9566279	164036783							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129941	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCc1cccc(C(=O)N3CCC4(CCCC(=O)NC4=O)C3)c1)c1nnc(C)n1-2	InChI=1S/C41H46ClN7O4S/c1-25-26(2)54-39-35(25)36(29-14-16-31(42)17-15-29)44-32(37-47-46-27(3)49(37)39)23-34(51)43-20-7-5-4-6-10-28-11-8-12-30(22-28)38(52)48-21-19-41(24-48)18-9-13-33(50)45-40(41)53/h8,11-12,14-17,22,32H,4-7,9-10,13,18-21,23-24H2,1-3H3,(H,43,51)(H,45,50,53)	VPLORICNGYFYKK-UHFFFAOYSA-N	95540	2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.02,6]trideca-2::US20250388593, Example 308	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95540	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95540&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5013108	164036784							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129949	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCN1CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C1)c1nnc(C)n1-2	InChI=1S/C38H45ClN8O5S/c1-22-23(2)53-36-32(22)33(25-10-12-26(39)13-11-25)41-27(34-44-43-24(3)46(34)36)18-30(49)40-16-8-6-4-5-7-9-17-45-20-38(21-45)19-31(50)47(37(38)52)28-14-15-29(48)42-35(28)51/h10-13,27-28H,4-9,14-21H2,1-3H3,(H,40,49)(H,42,48,51)	RMBWBGRORWPKOF-UHFFFAOYSA-N	95541	US20250388593, Example 309	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95541	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95541&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2948274	164036785							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129950	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCc1cn(C3CCCC(=O)NC3=O)nn1)c1nnc(C)n1-2	InChI=1S/C34H40ClN9O3S/c1-20-21(2)48-34-30(20)31(23-13-15-24(35)16-14-23)37-26(32-41-39-22(3)44(32)34)18-29(46)36-17-8-6-4-5-7-10-25-19-43(42-40-25)27-11-9-12-28(45)38-33(27)47/h13-16,19,26-27H,4-12,17-18H2,1-3H3,(H,36,46)(H,38,45,47)	NGVAGMGVZUHYTM-UHFFFAOYSA-N	95542	US20250388593, Example 310	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95542	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95542&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1338529	164036786							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129951	CC1=NNC2[C@H](CC(=O)NCCCCCCc3ccc(S(=O)(=O)N(C)C4CCCC(=O)NC4=O)cc3)N=C(c3ccc(Cl)cc3)c3c(sc(C)c3C)N12	InChI=1S/C38H46ClN7O5S2/c1-23-24(2)52-38-34(23)35(27-15-17-28(39)18-16-27)41-30(36-44-43-25(3)46(36)38)22-33(48)40-21-8-6-5-7-10-26-13-19-29(20-14-26)53(50,51)45(4)31-11-9-12-32(47)42-37(31)49/h13-20,30-31,36,44H,5-12,21-22H2,1-4H3,(H,40,48)(H,42,47,49)	AHCSUNKUFNTDKU-UHFFFAOYSA-N	95543	US20250388593, Example 311	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95543	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95543&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2192241	164036787							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129952	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCNc1ccc3nc(N4CCCC(=O)NC4=O)sc3c1)c1nnc(C)n1-2	InChI=1S/C38H42ClN9O3S2/c1-22-23(2)52-36-33(22)34(25-11-13-26(39)14-12-25)42-29(35-46-45-24(3)48(35)36)21-32(50)41-18-8-6-4-5-7-17-40-27-15-16-28-30(20-27)53-38(43-28)47-19-9-10-31(49)44-37(47)51/h11-16,20,29,40H,4-10,17-19,21H2,1-3H3,(H,41,50)(H,44,49,51)	NQEMKINHZPKSDU-UHFFFAOYSA-N	95544	US20250388593, Example 312	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95544	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95544&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			774024	164036788							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129953	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCNc1ccc(N3CCC(N4CCCC(=O)NC4=O)C3=O)cc1)c1nnc(C)n1-2	InChI=1S/C41H48ClN9O4S/c1-25-26(2)56-40-36(25)37(28-11-13-29(42)14-12-28)45-32(38-48-47-27(3)51(38)40)24-35(53)44-21-8-6-4-5-7-20-43-30-15-17-31(18-16-30)49-23-19-33(39(49)54)50-22-9-10-34(52)46-41(50)55/h11-18,32-33,43H,4-10,19-24H2,1-3H3,(H,44,53)(H,46,52,55)	KMALUONDLVLMIV-UHFFFAOYSA-N	95545	US20250388593, Example 313	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95545	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95545&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3220850	164036789							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129954	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCNc1ccc(N3CCC4(CCCCNC4=O)CC3=O)cc1)c1nnc(C)n1-2	InChI=1S/C42H51ClN8O3S/c1-27-28(2)55-40-37(27)38(30-11-13-31(43)14-12-30)47-34(39-49-48-29(3)51(39)40)25-35(52)45-22-9-6-4-5-8-21-44-32-15-17-33(18-16-32)50-24-20-42(26-36(50)53)19-7-10-23-46-41(42)54/h11-18,34,44H,4-10,19-26H2,1-3H3,(H,45,52)(H,46,54)	QDECLGFVFRTXFR-UHFFFAOYSA-N	95546	US20250388593, Example 314	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95546	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95546&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			952237	164036790							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129955	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCNc1nccc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)n1)c1nnc(C)n1-2	InChI=1S/C37H38ClN11O5S/c1-19-20(2)55-34-30(19)31(22-5-7-23(38)8-6-22)42-24(32-46-45-21(3)48(32)34)15-28(51)39-12-4-13-40-36-41-14-11-26(43-36)47-17-37(18-47)16-29(52)49(35(37)54)25-9-10-27(50)44-33(25)53/h5-8,11,14,24-25H,4,9-10,12-13,15-18H2,1-3H3,(H,39,51)(H,40,41,43)(H,44,50,53)	ITCZNTPKFYQAHO-UHFFFAOYSA-N	95547	US20250388593, Example 315	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95547	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95547&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3142730	164036791							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129956	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCc1ccc(-c3cn(C4CCCC(=O)NC4=O)nn3)cc1)c1nnc(C)n1-2	InChI=1S/C39H42ClN9O3S/c1-23-24(2)53-39-35(23)36(28-16-18-29(40)19-17-28)42-30(37-46-44-25(3)49(37)39)21-34(51)41-20-7-5-4-6-9-26-12-14-27(15-13-26)31-22-48(47-45-31)32-10-8-11-33(50)43-38(32)52/h12-19,22,30,32H,4-11,20-21H2,1-3H3,(H,41,51)(H,43,50,52)	OQTPCKLBPCCNLG-UHFFFAOYSA-N	95548	US20250388593, Example 316	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95548	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95548&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			91899563	164036792							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129957	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCc1ccc(S(=O)(=O)N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)cc1)c1nnc(C)n1-2	InChI=1S/C38H37ClN8O7S2/c1-20-21(2)55-36-32(20)33(24-6-8-25(39)9-7-24)41-27(34-44-43-22(3)46(34)36)16-30(49)40-15-14-23-4-10-26(11-5-23)56(53,54)45-18-38(19-45)17-31(50)47(37(38)52)28-12-13-29(48)42-35(28)51/h4-11,27-28H,12-19H2,1-3H3,(H,40,49)(H,42,48,51)	PWLMGDMUBUIGKV-UHFFFAOYSA-N	95549	US20250388593, Example 317	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95549	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95549&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4562748	164036793							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129958	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCn1ccc3c(N4CC5(CC(=O)N(C6CCC(=O)NC6=O)C5=O)C4)ncnc31)c1nnc(C)n1-2	InChI=1S/C44H48ClN11O5S/c1-25-26(2)62-42-36(25)37(28-10-12-29(45)13-11-28)49-31(40-52-51-27(3)55(40)42)20-34(58)46-17-8-6-4-5-7-9-18-53-19-16-30-38(53)47-24-48-39(30)54-22-44(23-54)21-35(59)56(43(44)61)32-14-15-33(57)50-41(32)60/h10-13,16,19,24,31-32H,4-9,14-15,17-18,20-23H2,1-3H3,(H,46,58)(H,50,57,60)	VUFKXVLHKFWNOF-UHFFFAOYSA-N	95550	US20250388593, Example 318	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95550	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95550&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2099133	164036794							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129959	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCn1ccc3c(N4CCC5(CCCC(=O)NC5=O)C4)ncnc31)c1nnc(C)n1-2	InChI=1S/C42H49ClN10O3S/c1-26-27(2)57-40-35(26)36(29-12-14-30(43)15-13-29)47-32(39-50-49-28(3)53(39)40)23-34(55)44-19-8-6-4-5-7-9-20-51-21-16-31-37(51)45-25-46-38(31)52-22-18-42(24-52)17-10-11-33(54)48-41(42)56/h12-16,21,25,32H,4-11,17-20,22-24H2,1-3H3,(H,44,55)(H,48,54,56)	QUYMFZQLECREDM-UHFFFAOYSA-N	95551	US20250388593, Example 319	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95551	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95551&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2708830	164036795							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129960	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCOc1ccc(C#N)c(N3CCC4(CCCC(=O)NC4=O)C3)c1)c1nnc(C)n1-2	InChI=1S/C43H49ClN8O4S/c1-27-28(2)57-41-38(27)39(30-12-15-32(44)16-13-30)47-34(40-50-49-29(3)52(40)41)24-37(54)46-20-8-6-4-5-7-9-22-56-33-17-14-31(25-45)35(23-33)51-21-19-43(26-51)18-10-11-36(53)48-42(43)55/h12-17,23,34H,4-11,18-22,24,26H2,1-3H3,(H,46,54)(H,48,53,55)	LTHIRRACQYNOCB-UHFFFAOYSA-N	95552	US20250388593, Example 320	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95552	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95552&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2122118	164036796							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129961	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCOc1ccc3c(c1)SC(N1CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C1)N3)c1nnc(C)n1-2	InChI=1S/C42H44ClN9O6S2/c1-22-23(2)59-39-35(22)36(25-7-9-26(43)10-8-25)45-29(37-49-48-24(3)51(37)39)18-33(54)44-15-5-4-6-16-58-27-11-12-28-31(17-27)60-41(46-28)50-20-42(21-50)19-34(55)52(40(42)57)30-13-14-32(53)47-38(30)56/h7-12,17,29-30,41,46H,4-6,13-16,18-21H2,1-3H3,(H,44,54)(H,47,53,56)	HWUQPMLSHWUHMC-UHFFFAOYSA-N	95553	US20250388593, Example 321	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95553	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95553&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			16324405	164036797							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129962	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCOc1ccc3nc(N4CCC5(CCCC(=O)NC5=O)C4)sc3c1)c1nnc(C)n1-2	InChI=1S/C40H43ClN8O4S2/c1-23-24(2)54-37-34(23)35(26-9-11-27(41)12-10-26)43-30(36-47-46-25(3)49(36)37)21-33(51)42-17-5-4-6-19-53-28-13-14-29-31(20-28)55-39(44-29)48-18-16-40(22-48)15-7-8-32(50)45-38(40)52/h9-14,20,30H,4-8,15-19,21-22H2,1-3H3,(H,42,51)(H,45,50,52)	KNJULYUGHFKKKM-UHFFFAOYSA-N	95554	US20250388593, Example 322	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95554	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95554&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			3264499	164036798							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129963	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCc1ccc(C(=O)N3CCC4(CCCC(=O)NC4=O)C3)cc1Cl)c1nnc(C)n1-2	InChI=1S/C41H45Cl2N7O4S/c1-24-25(2)55-39-35(24)36(28-13-15-30(42)16-14-28)45-32(37-48-47-26(3)50(37)39)22-34(52)44-19-7-5-4-6-9-27-11-12-29(21-31(27)43)38(53)49-20-18-41(23-49)17-8-10-33(51)46-40(41)54/h11-16,21,32H,4-10,17-20,22-23H2,1-3H3,(H,44,52)(H,46,51,54)	DJTGLXVSSWAQOP-UHFFFAOYSA-N	95555	US20250388593, Example 323	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95555	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95555&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6494320	164036799							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129964	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCc1cccc3c(C(=O)N4CCC5(CCCC(=O)NC5=O)C4)cccc13)c1nnc(C)n1-2	InChI=1S/C45H48ClN7O4S/c1-27-28(2)58-43-39(27)40(31-17-19-32(46)20-18-31)48-36(41-51-50-29(3)53(41)43)25-38(55)47-23-7-5-4-6-11-30-12-8-14-34-33(30)13-9-15-35(34)42(56)52-24-22-45(26-52)21-10-16-37(54)49-44(45)57/h8-9,12-15,17-20,36H,4-7,10-11,16,21-26H2,1-3H3,(H,47,55)(H,49,54,57)	SJOJUYMOKBWLQY-UHFFFAOYSA-N	95556	US20250388593, Example 324	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95556	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95556&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			20970585	164036800							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129965	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCn1ccc3c(C(=O)N4CCC5(CCCC(=O)NC5=O)CC4)cccc31)c1nnc(C)n1-2	InChI=1S/C44H49ClN8O4S/c1-27-28(2)58-42-38(27)39(30-13-15-31(45)16-14-30)47-34(40-50-49-29(3)53(40)42)26-37(55)46-21-6-4-5-7-22-51-23-17-32-33(10-8-11-35(32)51)41(56)52-24-19-44(20-25-52)18-9-12-36(54)48-43(44)57/h8,10-11,13-17,23,34H,4-7,9,12,18-22,24-26H2,1-3H3,(H,46,55)(H,48,54,57)	CQDVPQLGTOPMBY-UHFFFAOYSA-N	95557	US20250388593, Example 326	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95557	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95557&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1088717	164036801							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129966	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCc1ccc(C(=O)N3CCN(C4CCCC(=O)NC4=O)C(=O)C3)cc1Cl)c1nnc(C)n1-2	InChI=1S/C42H46Cl2N8O5S/c1-24-25(2)58-42-37(24)38(28-14-16-30(43)17-15-28)46-32(39-49-48-26(3)52(39)42)22-35(54)45-18-7-5-4-6-9-27-12-13-29(21-31(27)44)41(57)50-19-20-51(36(55)23-50)33-10-8-11-34(53)47-40(33)56/h12-17,21,32-33H,4-11,18-20,22-23H2,1-3H3,(H,45,54)(H,47,53,56)	FXLJSFBAESPGBR-UHFFFAOYSA-N	95558	US20250388593, Example 327	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95558	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95558&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4147163	164036802							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129967	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)c1cc3c(N4CCC5(CCCC(=O)NC5=O)C4)ncnc3n1C)c1nnc(C)n1-2	InChI=1S/C44H52ClN11O4S/c1-26-27(2)61-42-36(26)37(29-13-15-30(45)16-14-29)50-32(40-53-52-28(3)56(40)42)23-35(58)46-19-9-7-5-6-8-10-20-47-41(59)33-22-31-38(54(33)4)48-25-49-39(31)55-21-18-44(24-55)17-11-12-34(57)51-43(44)60/h13-16,22,25,32H,5-12,17-21,23-24H2,1-4H3,(H,46,58)(H,47,59)(H,51,57,60)	SPKMTNUVBMEGHH-UHFFFAOYSA-N	95559	N-[8-[[2-[(9S)-7-(4-Chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.02,6]trideca-2::US20250388593, Example 328	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95559	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95559&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			91899564	164036803							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129968	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)c1ccc3nc(N4CCC5(CCCC(=O)NC5=O)C4)sc3c1)c1nnc(C)n1-2	InChI=1S/C44H50ClN9O4S2/c1-26-27(2)59-41-37(26)38(29-12-15-31(45)16-13-29)48-33(39-52-51-28(3)54(39)41)24-36(56)46-20-8-6-4-5-7-9-21-47-40(57)30-14-17-32-34(23-30)60-43(49-32)53-22-19-44(25-53)18-10-11-35(55)50-42(44)58/h12-17,23,33H,4-11,18-22,24-25H2,1-3H3,(H,46,56)(H,47,57)(H,50,55,58)	CPEUHKVEFSZSDV-UHFFFAOYSA-N	95560	US20250388593, Example 329	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95560	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95560&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			133081083	164036804							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129969	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)c1ccc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)nc1)c1nnc(C)n1-2	InChI=1S/C44H49ClN10O6S/c1-25-26(2)62-42-37(25)38(28-10-13-30(45)14-11-28)49-31(39-52-51-27(3)54(39)42)20-35(57)46-18-8-6-4-5-7-9-19-47-40(59)29-12-16-33(48-22-29)53-23-44(24-53)21-36(58)55(43(44)61)32-15-17-34(56)50-41(32)60/h10-14,16,22,31-32H,4-9,15,17-21,23-24H2,1-3H3,(H,46,57)(H,47,59)(H,50,56,60)	MMFCNANFHJSMLL-UHFFFAOYSA-N	95561	US20250388593, Example 330	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95561	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95561&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5299834	164036805							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129970	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)CN1CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C1)c1nnc(C)n1-2	InChI=1S/C40H48ClN9O6S/c1-23-24(2)57-38-34(23)35(26-10-12-27(41)13-11-26)44-28(36-47-46-25(3)49(36)38)18-31(52)42-16-8-6-4-5-7-9-17-43-32(53)20-48-21-40(22-48)19-33(54)50(39(40)56)29-14-15-30(51)45-37(29)55/h10-13,28-29H,4-9,14-22H2,1-3H3,(H,42,52)(H,43,53)(H,45,51,55)	XUIFDPLURSDDDN-UHFFFAOYSA-N	95562	US20250388593, Example 331	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95562	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95562&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4156786	164036806							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129971	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)Cn1c(=O)n(C3CCCC(=O)NC3=O)c3ccccc31)c1nnc(C)n1-2	InChI=1S/C42H48ClN9O5S/c1-25-26(2)58-41-37(25)38(28-17-19-29(43)20-18-28)46-30(39-49-48-27(3)51(39)41)23-35(54)44-21-10-6-4-5-7-11-22-45-36(55)24-50-31-13-8-9-14-32(31)52(42(50)57)33-15-12-16-34(53)47-40(33)56/h8-9,13-14,17-20,30,33H,4-7,10-12,15-16,21-24H2,1-3H3,(H,44,54)(H,45,55)(H,47,53,56)	QHGDIJNBWZOFRR-UHFFFAOYSA-N	95563	US20250388593, Example 332	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95563	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95563&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			11405500	164036807							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129972	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)CCc1cccc3c1n(C)c(=O)n3C1CCCC(=O)NC1=O)c1nnc(C)n1-2	InChI=1S/C44H52ClN9O5S/c1-26-27(2)60-43-38(26)39(29-17-20-31(45)21-18-29)48-32(41-51-50-28(3)53(41)43)25-37(57)47-24-10-8-6-5-7-9-23-46-35(55)22-19-30-13-11-14-33-40(30)52(4)44(59)54(33)34-15-12-16-36(56)49-42(34)58/h11,13-14,17-18,20-21,32,34H,5-10,12,15-16,19,22-25H2,1-4H3,(H,46,55)(H,47,57)(H,49,56,58)	HIUNHNCUFRRBAM-UHFFFAOYSA-N	95564	US20250388593, Example 333	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95564	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95564&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2992149	164036808							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129973	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)CCc1nn(C3CCCC(=O)NC3=O)c3ccccc13)c1nnc(C)n1-2	InChI=1S/C43H50ClN9O4S/c1-26-27(2)58-43-39(26)40(29-17-19-30(44)20-18-29)47-33(41-50-49-28(3)52(41)43)25-38(56)46-24-11-7-5-4-6-10-23-45-36(54)22-21-32-31-13-8-9-14-34(31)53(51-32)35-15-12-16-37(55)48-42(35)57/h8-9,13-14,17-20,33,35H,4-7,10-12,15-16,21-25H2,1-3H3,(H,45,54)(H,46,56)(H,48,55,57)	PSYYEQYXFLOMHJ-UHFFFAOYSA-N	95565	US20250388593, Example 334	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95565	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95565&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			2667330	164036809							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129974	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)c1ccc(N3CCC4(CCCC(=O)NC4=O)CC3=O)nc1)c1nnc(C)n1-2	InChI=1S/C43H50ClN9O5S/c1-26-27(2)59-41-37(26)38(29-12-15-31(44)16-13-29)48-32(39-51-50-28(3)53(39)41)23-35(55)45-20-8-6-4-5-7-9-21-46-40(57)30-14-17-33(47-25-30)52-22-19-43(24-36(52)56)18-10-11-34(54)49-42(43)58/h12-17,25,32H,4-11,18-24H2,1-3H3,(H,45,55)(H,46,57)(H,49,54,58)	XJAAJYRGTRIJCO-UHFFFAOYSA-N	95566	US20250388593, Example 335	Protein cereblon [318-426]				>100000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95566	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95566&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			78413546	164036810							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129975	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)CCc1ccc(-c3nn(C4CCCC(=O)NC4=O)c(=O)n3C)cc1)c1nnc(C)n1-2	InChI=1S/C45H53ClN10O5S/c1-27-28(2)62-44-39(27)40(31-19-21-33(46)22-20-31)49-34(42-52-51-29(3)55(42)44)26-38(59)48-25-10-8-6-5-7-9-24-47-36(57)23-16-30-14-17-32(18-15-30)41-53-56(45(61)54(41)4)35-12-11-13-37(58)50-43(35)60/h14-15,17-22,34-35H,5-13,16,23-26H2,1-4H3,(H,47,57)(H,48,59)(H,50,58,60)	DFTFWQKJEFLECJ-UHFFFAOYSA-N	95567	US20250388593, Example 336	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95567	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95567&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			5153388	164036811							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129976	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)N[C@@H](CC(=O)NCCCCCCCCNC(=O)c1ccc3nc(N4CC5(CC(=O)N(C6CCC(=O)NC6=O)C5=O)C4)sc3c1)c1nnc(C)n1-2	InChI=1S/C46H51ClN10O6S2/c1-25-26(2)64-43-38(25)39(28-10-13-30(47)14-11-28)50-32(40-54-53-27(3)56(40)43)21-36(59)48-18-8-6-4-5-7-9-19-49-41(61)29-12-15-31-34(20-29)65-45(51-31)55-23-46(24-55)22-37(60)57(44(46)63)33-16-17-35(58)52-42(33)62/h10-15,20,32-33,39,50H,4-9,16-19,21-24H2,1-3H3,(H,48,59)(H,49,61)(H,52,58,62)	IRHMIHBEQWFGMI-UHFFFAOYSA-N	95568	US20250388593, Example 337	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95568	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95568&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1163944	164036812							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129977	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)N[C@@H](CC(=O)NCCCCCCCCNC(=O)c1ccc(OC3CCCC(=O)NC3=O)nc1)c1nnc(C)n1-2	InChI=1S/C39H47ClN8O5S/c1-23-24(2)54-39-34(23)35(26-13-16-28(40)17-14-26)44-29(36-47-46-25(3)48(36)39)21-32(50)41-19-8-6-4-5-7-9-20-42-37(51)27-15-18-33(43-22-27)53-30-11-10-12-31(49)45-38(30)52/h13-18,22,29-30,35,44H,4-12,19-21H2,1-3H3,(H,41,50)(H,42,51)(H,45,49,52)	ZDQQFDRHEKOZBR-UHFFFAOYSA-N	95569	US20250388593, Example 338	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95569	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95569&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6495856	164036813							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129978	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)COc1ccc(C#N)c(N3CCC4(CCCC(=O)NC4=O)C3)c1)c1nnc(C)n1-2	InChI=1S/C45H52ClN9O5S/c1-28-29(2)61-43-40(28)41(31-12-15-33(46)16-13-31)50-35(42-53-52-30(3)55(42)43)24-38(57)48-20-8-6-4-5-7-9-21-49-39(58)26-60-34-17-14-32(25-47)36(23-34)54-22-19-45(27-54)18-10-11-37(56)51-44(45)59/h12-17,23,35H,4-11,18-22,24,26-27H2,1-3H3,(H,48,57)(H,49,58)(H,51,56,59)	YRKDUHNLJTWQDC-UHFFFAOYSA-N	95570	US20250388593, Example 339	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95570	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95570&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6463398	164036814							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129979	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)COc1ccccc1-c1cn(C3CCCC(=O)NC3=O)nn1)c1nnc(C)n1-2	InChI=1S/C43H49ClN10O5S/c1-26-27(2)60-43-39(26)40(29-17-19-30(44)20-18-29)47-32(41-51-49-28(3)54(41)43)23-37(56)45-21-10-6-4-5-7-11-22-46-38(57)25-59-35-15-9-8-13-31(35)33-24-53(52-50-33)34-14-12-16-36(55)48-42(34)58/h8-9,13,15,17-20,24,32,34H,4-7,10-12,14,16,21-23,25H2,1-3H3,(H,45,56)(H,46,57)(H,48,55,58)	VXUFGYGFPINWBG-UHFFFAOYSA-N	95571	US20250388593, Example 340	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95571	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95571&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			6501570	164036815							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129980	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)CCc1ccc3c(c1)oc(=O)n3C1CCCC(=O)NC1=O)c1nnc(C)n1-2	InChI=1S/C43H49ClN8O6S/c1-25-26(2)59-42-38(25)39(29-15-17-30(44)18-16-29)47-31(40-50-49-27(3)51(40)42)24-37(55)46-22-9-7-5-4-6-8-21-45-35(53)20-14-28-13-19-32-34(23-28)58-43(57)52(32)33-11-10-12-36(54)48-41(33)56/h13,15-19,23,31,33H,4-12,14,20-22,24H2,1-3H3,(H,45,53)(H,46,55)(H,48,54,56)	HDGFGQJPACYVGG-UHFFFAOYSA-N	95572	US20250388593, Example 341	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95572	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95572&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1511103	164036816							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129981	CC1=C(C)C2C(c3ccc(Cl)cc3)N[C@@H](CC(=O)NCCCCCCCCNC(=O)CCc3ccc4c(c3)sc(=O)n4C3CCCC(=O)NC3=O)c3nnc(C)n3C2S1	InChI=1S/C43H53ClN8O5S2/c1-25-26(2)58-42-38(25)39(29-15-17-30(44)18-16-29)47-31(40-50-49-27(3)51(40)42)24-37(55)46-22-9-7-5-4-6-8-21-45-35(53)20-14-28-13-19-32-34(23-28)59-43(57)52(32)33-11-10-12-36(54)48-41(33)56/h13,15-19,23,31,33,38-39,42,47H,4-12,14,20-22,24H2,1-3H3,(H,45,53)(H,46,55)(H,48,54,56)	IHSYJKYHOFQELK-UHFFFAOYSA-N	95573	N-[8-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]octyl]-3-[3-(2,7-dioxoazepan-3-yl)-2-oxo-1,3-benzothiazol-6-yl]propanamide::US20250388593, Example 342	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95573	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95573&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			133081084	164036817							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129982	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)CCc1ccc3c(c1)sc(=O)n3C1CCCC(=O)NC1=O)c1nnc(C)n1-2	InChI=1S/C43H49ClN8O5S2/c1-25-26(2)58-42-38(25)39(29-15-17-30(44)18-16-29)47-31(40-50-49-27(3)51(40)42)24-37(55)46-22-9-7-5-4-6-8-21-45-35(53)20-14-28-13-19-32-34(23-28)59-43(57)52(32)33-11-10-12-36(54)48-41(33)56/h13,15-19,23,31,33H,4-12,14,20-22,24H2,1-3H3,(H,45,53)(H,46,55)(H,48,54,56)	HCCRLNGYWASQOE-UHFFFAOYSA-N	95574	US20250388593, Example 343	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95574	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95574&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			133081085	164036818							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129983	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)CCc1ccc3c(=O)n(C4CCCC(=O)NC4=O)c(=O)n(C)c3c1)c1nnc(C)n1-2	InChI=1S/C45H52ClN9O6S/c1-26-27(2)62-44-39(26)40(30-16-18-31(46)19-17-30)49-33(41-52-51-28(3)54(41)44)25-38(58)48-23-10-8-6-5-7-9-22-47-36(56)21-15-29-14-20-32-35(24-29)53(4)45(61)55(43(32)60)34-12-11-13-37(57)50-42(34)59/h14,16-20,24,33-34H,5-13,15,21-23,25H2,1-4H3,(H,47,56)(H,48,58)(H,50,57,59)	KRCMKFOPBPLBRP-UHFFFAOYSA-N	95575	US20250388593, Example 344	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95575	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95575&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			24793989	164036819							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129984	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCNC(=O)CN1CCC3(CCCC(=O)NC3=O)CC1=O)c1nnc(C)n1-2	InChI=1S/C38H47ClN8O5S/c1-23-24(2)53-36-33(23)34(26-11-13-27(39)14-12-26)42-28(35-45-44-25(3)47(35)36)20-30(49)40-17-7-5-4-6-8-18-41-31(50)22-46-19-16-38(21-32(46)51)15-9-10-29(48)43-37(38)52/h11-14,28H,4-10,15-22H2,1-3H3,(H,40,49)(H,41,50)(H,43,48,52)	NTCBVQIWOLROIG-UHFFFAOYSA-N	95576	US20250388593, Example 345	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95576	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95576&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			8072382	164036820							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129985	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)CCc1ccc3c(N4CCCC(=O)NC4=O)nn(C)c3c1)c1nnc(C)n1-2	InChI=1S/C43H51ClN10O4S/c1-26-27(2)59-42-38(26)39(30-15-17-31(44)18-16-30)47-33(41-50-49-28(3)54(41)42)25-37(57)46-22-10-8-6-5-7-9-21-45-35(55)20-14-29-13-19-32-34(24-29)52(4)51-40(32)53-23-11-12-36(56)48-43(53)58/h13,15-19,24,33H,5-12,14,20-23,25H2,1-4H3,(H,45,55)(H,46,57)(H,48,56,58)	MBTIBZGVHHQLFC-UHFFFAOYSA-N	95577	US20250388593, Example 346	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95577	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95577&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			24817981	164036821							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129986	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)N[C@@H](CC(=O)NCCCCCCCNC(=O)COc1cccc(C(=O)NC3CCCC(=O)NC3=O)n1)c1nnc(C)n1-2	InChI=1S/C40H48ClN9O6S/c1-23-24(2)57-40-35(23)36(26-15-17-27(41)18-16-26)45-30(37-49-48-25(3)50(37)40)21-32(52)42-19-7-5-4-6-8-20-43-33(53)22-56-34-14-10-12-28(44-34)38(54)46-29-11-9-13-31(51)47-39(29)55/h10,12,14-18,29-30,36,45H,4-9,11,13,19-22H2,1-3H3,(H,42,52)(H,43,53)(H,46,54)(H,47,51,55)	NOPPIIOIFWOCHG-UHFFFAOYSA-N	95578	US20250388593, Example 347	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95578	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95578&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4905770	164036822							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129987	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)/C=C/c1cccc3c1N(C)C(=O)C3(C)N1C=CCC(=O)NC1=O)c1nnc(C)n1-2	InChI=1S/C45H50ClN9O5S/c1-27-28(2)61-42-38(27)39(30-17-20-32(46)21-18-30)49-34(41-52-51-29(3)55(41)42)26-37(58)48-24-11-9-7-6-8-10-23-47-35(56)22-19-31-14-12-15-33-40(31)53(5)43(59)45(33,4)54-25-13-16-36(57)50-44(54)60/h12-15,17-22,25,34H,6-11,16,23-24,26H2,1-5H3,(H,47,56)(H,48,58)(H,50,57,60)	LMBLMXREIFRXGC-UHFFFAOYSA-N	95579	US20250388593, Example 348	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95579	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95579&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4975949	164036823							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129988	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)/C=C/c1ccc([C@H]3C[C@H](N4C=CCC(=O)NC4=O)C(=O)N3C)cc1)c1nnc(C)n1-2	InChI=1S/C46H52ClN9O5S/c1-28-29(2)62-45-41(28)42(33-18-20-34(47)21-19-33)50-35(43-53-52-30(3)56(43)45)26-40(59)49-24-10-8-6-5-7-9-23-48-38(57)22-15-31-13-16-32(17-14-31)36-27-37(44(60)54(36)4)55-25-11-12-39(58)51-46(55)61/h11,13-22,25,35-37H,5-10,12,23-24,26-27H2,1-4H3,(H,48,57)(H,49,59)(H,51,58,61)	MUUDDGOMDFKDOL-UHFFFAOYSA-N	95580	US20250388593, Example 349	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95580	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95580&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4902523	164036824							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129989	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCNC(=O)Cn1c(=O)c(=O)n(C3CCCC(=O)NC3=O)c3ccccc31)c1nnc(C)n1-2	InChI=1S/C42H46ClN9O6S/c1-24-25(2)59-42-36(24)37(27-16-18-28(43)19-17-27)46-29(38-49-48-26(3)51(38)42)22-34(54)44-20-9-5-4-6-10-21-45-35(55)23-50-30-12-7-8-13-31(30)52(41(58)40(50)57)32-14-11-15-33(53)47-39(32)56/h7-8,12-13,16-19,29,32H,4-6,9-11,14-15,20-23H2,1-3H3,(H,44,54)(H,45,55)(H,47,53,56)	LCGQKDBBERNFAL-UHFFFAOYSA-N	95581	US20250388593, Example 350	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95581	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95581&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			1771880	164036825							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129990	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)CN1C(=O)[C@@](C)(N3CCCC(=O)NC3=O)c3ccccc31)c1nnc(C)n1-2	InChI=1S/C43H50ClN9O5S/c1-26-27(2)59-40-37(26)38(29-17-19-30(44)20-18-29)47-32(39-50-49-28(3)53(39)40)24-35(55)45-21-11-7-5-6-8-12-22-46-36(56)25-51-33-15-10-9-14-31(33)43(4,41(51)57)52-23-13-16-34(54)48-42(52)58/h9-10,14-15,17-20,32H,5-8,11-13,16,21-25H2,1-4H3,(H,45,55)(H,46,56)(H,48,54,58)	BCVZQZCKOCHVNL-UHFFFAOYSA-N	95582	2-[(9S)-7-(4-Chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.02,6]trideca-2::US20250388593, Example 352	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95582	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95582&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4906603	164036826							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129991	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCCCC(=O)N1CCC(c3cnc(N4CCC5(CCCC(=O)NC5=O)C4)nc3)CC1)c1nnc(C)n1-2	InChI=1S/C48H61ClN10O4S/c1-31-32(2)64-45-42(31)43(35-15-17-37(49)18-16-35)53-38(44-56-55-33(3)59(44)45)27-40(61)50-23-11-9-7-5-4-6-8-10-14-41(62)57-24-19-34(20-25-57)36-28-51-47(52-29-36)58-26-22-48(30-58)21-12-13-39(60)54-46(48)63/h15-18,28-29,34,38H,4-14,19-27,30H2,1-3H3,(H,50,61)(H,54,60,63)	QLZGISLMFIAEJI-UHFFFAOYSA-N	95583	US20250388593, Example 354	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95583	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95583&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4911805	164036827							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129992	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCCCC(=O)N1CCC(c3cccc(NC45CCC(CC4)C(=O)NC5=O)c3)CC1)c1nnc(C)n1-2	InChI=1S/C49H61ClN8O4S/c1-31-32(2)63-47-43(31)44(35-16-18-38(50)19-17-35)52-40(45-56-55-33(3)58(45)47)30-41(59)51-26-11-9-7-5-4-6-8-10-15-42(60)57-27-22-34(23-28-57)37-13-12-14-39(29-37)54-49-24-20-36(21-25-49)46(61)53-48(49)62/h12-14,16-19,29,34,36,40,54H,4-11,15,20-28,30H2,1-3H3,(H,51,59)(H,53,61,62)	OKJAOOTVRFXNEE-UHFFFAOYSA-N	95584	US20250388593, Example 355	Protein cereblon [318-426]				 75000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95584	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95584&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			7855787	164036828							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129993	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCCCC(=O)N1CCC(c3ccc(OC4CCCC(=O)NC4=O)cc3)CC1)c1nnc(C)n1-2	InChI=1S/C47H58ClN7O5S/c1-30-31(2)61-47-43(30)44(35-16-20-36(48)21-17-35)50-38(45-53-52-32(3)55(45)47)29-41(57)49-26-11-9-7-5-4-6-8-10-15-42(58)54-27-24-34(25-28-54)33-18-22-37(23-19-33)60-39-13-12-14-40(56)51-46(39)59/h16-23,34,38-39H,4-15,24-29H2,1-3H3,(H,49,57)(H,51,56,59)	GFHUCYRLWSFBPJ-UHFFFAOYSA-N	95585	US20250388593, Example 356	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95585	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95585&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4907109	164036829							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129994	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCCCC(=O)N1CCc3c(ncnc3N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)C1)c1nnc(C)n1-2	InChI=1S/C48H56ClN11O6S/c1-28-29(2)67-46-41(28)42(31-13-15-32(49)16-14-31)53-34(44-56-55-30(3)59(44)46)22-38(62)50-20-11-9-7-5-4-6-8-10-12-39(63)57-21-19-33-35(24-57)51-27-52-43(33)58-25-48(26-58)23-40(64)60(47(48)66)36-17-18-37(61)54-45(36)65/h13-16,27,34,36H,4-12,17-26H2,1-3H3,(H,50,62)(H,54,61,65)	DSIYHDAIADKPDZ-UHFFFAOYSA-N	95586	US20250388593, Example 357	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95586	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95586&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			8034762	164036830							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129995	Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCCCC(=O)N1CCC(c3ccc(C45CCC(O4)C(=O)NC5=O)cc3)CC1)c1nnc(C)n1-2	InChI=1S/C47H56ClN7O5S/c1-29-30(2)61-45-41(29)42(34-15-19-36(48)20-16-34)50-37(43-53-52-31(3)55(43)45)28-39(56)49-25-11-9-7-5-4-6-8-10-12-40(57)54-26-22-33(23-27-54)32-13-17-35(18-14-32)47-24-21-38(60-47)44(58)51-46(47)59/h13-20,33,37-38H,4-12,21-28H2,1-3H3,(H,49,56)(H,51,58,59)	JUHQNWRFSGKHHA-UHFFFAOYSA-N	95587	US20250388593, Example 358	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95587	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95587&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4912034	164036831							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129996	C[C@@H]8CC2c1ccccc1NC2[C@@H](c7cnc(N6CCC(CN(C)CCCCCCCc3cccc4c3n(C)c(=O)n4C5CCCC(=O)NC5=O)CC6)nc7)N8CC(C)(C)C	InChI=1S/C49H69N9O3/c1-33-28-38-37-18-11-12-19-39(37)52-43(38)45(57(33)32-49(2,3)4)36-29-50-47(51-30-36)56-26-23-34(24-27-56)31-54(5)25-13-9-7-8-10-16-35-17-14-20-40-44(35)55(6)48(61)58(40)41-21-15-22-42(59)53-46(41)60/h11-12,14,17-20,29-30,33-34,38,41,43,45,52H,7-10,13,15-16,21-28,31-32H2,1-6H3,(H,53,59,60)	MNXUYZCHYCRTSN-UHFFFAOYSA-N	95588	US20250388593, Example 360-3	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95588	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95588&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4900934	164036832							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
129997	CCOC(=O)c1ccc(CCCCCCCN(C)C(=O)OC(C)(C)C)cc1	InChI=1S/C22H35NO4/c1-6-26-20(24)19-15-13-18(14-16-19)12-10-8-7-9-11-17-23(5)21(25)27-22(2,3)4/h13-16H,6-12,17H2,1-5H3	CHOJEHXYGLOTHO-UHFFFAOYSA-N	95589	Ethyl 4-[7-[tert-butoxycarbonyl(methyl) amino]heptyl]benzoate::US20250388593, Example 361-2	Protein cereblon [318-426]				<50000						US Patent		10.7270/Q2TX3M56			US20250388593	SAKAMAKI, S; NIWA, Y; IKUBO, M; SUGAMA, H	12/25/2025	5/6/2026	Mitsubishi Tanabe Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95589	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2087&target=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95589&enzyme=Protein+cereblon+%5B318-426%5D&column=ki&startPg=0&Increment=50&submit=Search			4973618	164036833							1	CTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTI	9CUO,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,4TZ4,9SFM,9OTY,7LPS,9HNE,9NR3,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9D0X,9D0W,7U8F,11MR,10AY,9HPJ,9HPI,9Q33,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9FJX,8OJH,8OIZ,9DWW,9DWV,9OUL,9SAI,9SAF,8UH6,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUK,9Q22,8G66,6H0G,6H0F,5FQD,9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9H59,9YA9,9Q2D,9Q03,9DQD,9W2F,9OS2	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4