BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
130624	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC3)CCN42)C(=O)N1	InChI=1S/C45H47N5O6/c51-34-10-11-35-40(21-34)56-27-37(29-4-2-1-3-5-29)43(35)30-6-8-32(9-7-30)48-16-14-28(15-17-48)23-47-18-19-49-33(25-47)26-55-41-22-36-31(20-39(41)49)24-50(45(36)54)38-12-13-42(52)46-44(38)53/h1-11,20-22,28,33,37-38,43,51H,12-19,23-27H2,(H,46,52,53)	TYEXTZBQGMCLAT-UHFFFAOYSA-N	96969	3-((S)-3-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)-8-oxo-1,2,3,4,4a,5,8,10- octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A1	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96969	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96969&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			15945251	164038213							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130625	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5F)CC3)CCN42)C(=O)N1	InChI=1S/C45H46FN5O6/c46-36-18-29(43-33-8-7-32(52)20-40(33)57-26-35(43)28-4-2-1-3-5-28)6-9-37(36)49-14-12-27(13-15-49)22-48-16-17-50-31(24-48)25-56-41-21-34-30(19-39(41)50)23-51(45(34)55)38-10-11-42(53)47-44(38)54/h1-9,18-21,27,31,35,38,43,52H,10-17,22-26H2,(H,47,53,54)	KUTJIEUAPQAQAC-UHFFFAOYSA-N	96970	3-((S)-3-((1-(2-fluoro-4-((3S,4R)-7- hydroxy-3-phenylchroman-4- yl)phenyl)piperidin-4-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A2	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96970	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96970&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			3336867	164038214							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130626	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CCC3(CC2)CCN(c2ccc([C@@H]5c6ccc(O)cc6OC[C@@H]5c5ccccc5)cc2)CC3)C4)C(=O)N1	InChI=1S/C47H47N5O7/c53-34-10-11-35-40(24-34)59-28-38(29-4-2-1-3-5-29)43(35)30-6-8-33(9-7-30)50-18-14-47(15-19-50)16-20-51(21-17-47)42(55)27-49-25-31-22-36-37(23-32(31)26-49)46(58)52(45(36)57)39-12-13-41(54)48-44(39)56/h1-11,22-24,38-39,43,53H,12-21,25-28H2,(H,48,54,56)	YDMQYRRRRMPTJD-UHFFFAOYSA-N	96971	2-(2,6-dioxopiperidin-3-yl)-6-(2-(9-(4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-3,9-diazaspiro[5.5]undecan-3- yl)-2-oxoethyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A3	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96971	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96971&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			6873016	164038215							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130627	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CCC3(CC2)CCN(c2ncc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cn2)CC3)C4)C(=O)N1	InChI=1S/C45H45N7O7/c53-31-6-7-32-37(20-31)59-26-35(27-4-2-1-3-5-27)40(32)30-21-46-44(47-22-30)51-16-12-45(13-17-51)10-14-50(15-11-45)39(55)25-49-23-28-18-33-34(19-29(28)24-49)43(58)52(42(33)57)36-8-9-38(54)48-41(36)56/h1-7,18-22,35-36,40,53H,8-17,23-26H2,(H,48,54,56)	CXEDLWYNPGRCDG-UHFFFAOYSA-N	96972	2-(2,6-dioxopiperidin-3-yl)-6-(2-(9-(5- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)pyrimidin-2-yl)-3,9- diazaspiro[5.5]undecan-3-yl)-2-oxoethyl)- 6,7-dihydropyrrolo[3,4-f]isoindole- 1,3(2H,5H)-dione::US20260000676, Compound A4	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96972	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96972&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			182791	164038216							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130628	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CCC3(CC2)CCN(c2ncc([C@@H]5c6ccc(O)cc6OC[C@@H]5c5ccccc5)cn2)CC3)C4)C(=O)N1	InChI=1S/C45H45N7O7/c53-31-6-7-32-37(20-31)59-26-35(27-4-2-1-3-5-27)40(32)30-21-46-44(47-22-30)51-16-12-45(13-17-51)10-14-50(15-11-45)39(55)25-49-23-28-18-33-34(19-29(28)24-49)43(58)52(42(33)57)36-8-9-38(54)48-41(36)56/h1-7,18-22,35-36,40,53H,8-17,23-26H2,(H,48,54,56)	CXEDLWYNPGRCDG-UHFFFAOYSA-N	96973	2-(2,6-dioxopiperidin-3-yl)-6-(2-(9-(5- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)pyrimidin-2-yl)-3,9- diazaspiro[5.5]undecan-3-yl)-2-oxoethyl)- 6,7-dihydropyrrolo[3,4-f]isoindole- 1,3(2H,5H)-dione::US20260000676, Compound A5	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96973	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96973&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1214438	164038217							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130629	O=C1CCC(N2Cc3c(ccc4c3OC[C@@H]3CN(CC5CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6F)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C45H46FN5O6/c46-36-20-29(42-33-8-7-31(52)21-40(33)56-26-35(42)28-4-2-1-3-5-28)6-10-37(36)49-16-14-27(15-17-49)22-48-18-19-50-30(23-48)25-57-43-34-24-51(39-12-13-41(53)47-44(39)54)45(55)32(34)9-11-38(43)50/h1-11,20-21,27,30,35,39,42,52H,12-19,22-26H2,(H,47,53,54)	WIZNLEVXEOBIOP-UHFFFAOYSA-N	96975	3-((S)-7-((1-(2-fluoro-4-((3S,4R)-7- hydroxy-3-phenylchroman-4- yl)phenyl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A6	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96975	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96975&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			16187882	164038219							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130630	O=C1CCC(N2Cc3c(ccc4c3OC[C@@H]3CN(CC5CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C45H47N5O6/c51-33-10-11-35-40(22-33)55-27-37(29-4-2-1-3-5-29)42(35)30-6-8-31(9-7-30)48-18-16-28(17-19-48)23-47-20-21-49-32(24-47)26-56-43-36-25-50(39-14-15-41(52)46-44(39)53)45(54)34(36)12-13-38(43)49/h1-13,22,28,32,37,39,42,51H,14-21,23-27H2,(H,46,52,53)	PKHVPEPQVNTSRM-UHFFFAOYSA-N	96976	3-((S)-7-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)-1-oxo-1,3,5,5a,6,7,8,9- octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A7	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96976	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96976&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			5296050	164038220							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130631	O=C1CCC(N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C45H47N5O6/c51-33-10-11-35-40(22-33)55-27-37(29-4-2-1-3-5-29)42(35)30-6-8-31(9-7-30)48-18-16-28(17-19-48)23-47-20-21-49-32(24-47)26-56-43-36-25-50(39-14-15-41(52)46-44(39)53)45(54)34(36)12-13-38(43)49/h1-13,22,28,32,37,39,42,51H,14-21,23-27H2,(H,46,52,53)	PKHVPEPQVNTSRM-UHFFFAOYSA-N	96977	3-((R)-7-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)-1-oxo-1,3,5,5a,6,7,8,9- octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A8	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96977	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96977&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			16188876	164038221							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130632	O=C1CCC(N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6F)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C45H46FN5O6/c46-36-20-29(42-33-8-7-31(52)21-40(33)56-26-35(42)28-4-2-1-3-5-28)6-10-37(36)49-16-14-27(15-17-49)22-48-18-19-50-30(23-48)25-57-43-34-24-51(39-12-13-41(53)47-44(39)54)45(55)32(34)9-11-38(43)50/h1-11,20-21,27,30,35,39,42,52H,12-19,22-26H2,(H,47,53,54)	WIZNLEVXEOBIOP-UHFFFAOYSA-N	96978	3-((R)-7-((1-(2-fluoro-4-((3S,4R)-7- hydroxy-3-phenylchroman-4- yl)phenyl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A9	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96978	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96978&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			975007	164038222							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130633	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCN(c5ncc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cn5)CC3)CCN42)C(=O)N1	InChI=1S/C43H45N7O6/c51-31-6-7-32-37(17-31)56-25-34(27-4-2-1-3-5-27)40(32)29-19-44-43(45-20-29)48-12-10-26(11-13-48)21-47-14-15-49-30(23-47)24-55-38-18-33-28(16-36(38)49)22-50(42(33)54)35-8-9-39(52)46-41(35)53/h1-7,16-20,26,30,34-35,40,51H,8-15,21-25H2,(H,46,52,53)	ZLOPFKOIACXTPD-UHFFFAOYSA-N	96979	3-((S)-3-((1-(5-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)pyrimidin-2- yl)piperidin-4-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A10	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96979	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96979&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			709461	164038223							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130634	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC3)CCN42)C(=O)N1	InChI=1S/C45H47N5O6/c51-34-10-11-35-40(21-34)56-27-37(29-4-2-1-3-5-29)43(35)30-6-8-32(9-7-30)48-16-14-28(15-17-48)23-47-18-19-49-33(25-47)26-55-41-22-36-31(20-39(41)49)24-50(45(36)54)38-12-13-42(52)46-44(38)53/h1-11,20-22,28,33,37-38,43,51H,12-19,23-27H2,(H,46,52,53)	TYEXTZBQGMCLAT-UHFFFAOYSA-N	96980	3-((S)-3-((1-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)-8-oxo-1,2,3,4,4a,5,8,10- octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A11	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96980	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96980&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			941737	164038224							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130635	COc1ccc([C@@H]2COc3cc(O)ccc3[C@@H]2c2ccc(N3CCC(CN4CCN5c6ccc7c(c6OC[C@@H]5C4)CN(C4CCC(=O)NC4=O)C7=O)CC3)cc2)cc1	InChI=1S/C46H49N5O7/c1-56-34-9-4-29(5-10-34)38-27-57-41-22-33(52)8-11-36(41)43(38)30-2-6-31(7-3-30)49-18-16-28(17-19-49)23-48-20-21-50-32(24-48)26-58-44-37-25-51(40-14-15-42(53)47-45(40)54)46(55)35(37)12-13-39(44)50/h2-13,22,28,32,38,40,43,52H,14-21,23-27H2,1H3,(H,47,53,54)	ZPARCMJNDCBEMK-UHFFFAOYSA-N	96981	3-((S)-7-((1-(4-((3R,4S)-7-hydroxy-3-(4- methoxyphenyl)chroman-4- yl)phenyl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A12	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96981	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96981&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			744402	164038225							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130636	COc1ccc([C@H]2COc3cc(O)ccc3[C@H]2c2ccc(N3CCC(CN4CCN5c6ccc7c(c6OC[C@@H]5C4)CN(C4CCC(=O)NC4=O)C7=O)CC3)cc2)cc1	InChI=1S/C46H49N5O7/c1-56-34-9-4-29(5-10-34)38-27-57-41-22-33(52)8-11-36(41)43(38)30-2-6-31(7-3-30)49-18-16-28(17-19-49)23-48-20-21-50-32(24-48)26-58-44-37-25-51(40-14-15-42(53)47-45(40)54)46(55)35(37)12-13-39(44)50/h2-13,22,28,32,38,40,43,52H,14-21,23-27H2,1H3,(H,47,53,54)	ZPARCMJNDCBEMK-UHFFFAOYSA-N	96982	3-((S)-7-((1-(4-((3S,4R)-7-hydroxy-3-(4- methoxyphenyl)chroman-4- yl)phenyl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A13	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96982	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96982&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2790597	164038226							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130637	Cc1nn(C2CCC(=O)NC2=O)c2ccc(N3CCN(CC4CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5F)CC4)CC3)cc12	InChI=1S/C44H47FN6O4/c1-28-35-24-32(8-12-38(35)51(47-28)40-13-14-42(53)46-44(40)54)49-21-19-48(20-22-49)26-29-15-17-50(18-16-29)39-11-7-31(23-37(39)45)43-34-10-9-33(52)25-41(34)55-27-36(43)30-5-3-2-4-6-30/h2-12,23-25,29,36,40,43,52H,13-22,26-27H2,1H3,(H,46,53,54)	XDZAITKNQBTMML-UHFFFAOYSA-N	96983	3-(5-(4-((1-(2-fluoro-4-((3S,4R)-7- hydroxy-3-phenylchroman-4- yl)phenyl)piperidin-4-yl)methyl)piperazin- 1-yl)-3-methyl-1H-indazol-1- yl)piperidine-2,6-dione::US20260000676, Compound A14	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96983	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96983&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1466457	164038227							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130638	COc1ccc([C@@H]2COc3cc(O)ccc3[C@@H]2c2ccc(N3CCC(CN4CCN5c6ccc7c(c6OC[C@H]5C4)CN(C4CCC(=O)NC4=O)C7=O)CC3)cc2)cc1	InChI=1S/C46H49N5O7/c1-56-34-9-4-29(5-10-34)38-27-57-41-22-33(52)8-11-36(41)43(38)30-2-6-31(7-3-30)49-18-16-28(17-19-49)23-48-20-21-50-32(24-48)26-58-44-37-25-51(40-14-15-42(53)47-45(40)54)46(55)35(37)12-13-39(44)50/h2-13,22,28,32,38,40,43,52H,14-21,23-27H2,1H3,(H,47,53,54)	ZPARCMJNDCBEMK-UHFFFAOYSA-N	96984	3-((R)-7-((1-(4-((3R,4S)-7-hydroxy-3-(4- methoxyphenyl)chroman-4- yl)phenyl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A15	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96984	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96984&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			9645547	164038228							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130639	COc1ccc([C@H]2COc3cc(O)ccc3[C@H]2c2ccc(N3CCC(CN4CCN5c6ccc7c(c6OC[C@H]5C4)CN(C4CCC(=O)NC4=O)C7=O)CC3)cc2)cc1	InChI=1S/C46H49N5O7/c1-56-34-9-4-29(5-10-34)38-27-57-41-22-33(52)8-11-36(41)43(38)30-2-6-31(7-3-30)49-18-16-28(17-19-49)23-48-20-21-50-32(24-48)26-58-44-37-25-51(40-14-15-42(53)47-45(40)54)46(55)35(37)12-13-39(44)50/h2-13,22,28,32,38,40,43,52H,14-21,23-27H2,1H3,(H,47,53,54)	ZPARCMJNDCBEMK-UHFFFAOYSA-N	96985	3-((R)-7-((1-(4-((3S,4R)-7-hydroxy-3-(4- methoxyphenyl)chroman-4- yl)phenyl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A16	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96985	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96985&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1099157	164038229							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130640	Cc1nn(C2CCC(=O)NC2=O)c2ccc(N3CCN(CC4CC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C4)CC3)cc12	InChI=1S/C47H52N6O4/c1-31-39-25-36(11-14-41(39)53(49-31)42-15-16-44(55)48-46(42)56)52-23-21-50(22-24-52)29-32-27-47(28-32)17-19-51(20-18-47)35-9-7-34(8-10-35)45-38-13-12-37(54)26-43(38)57-30-40(45)33-5-3-2-4-6-33/h2-14,25-26,32,40,42,45,54H,15-24,27-30H2,1H3,(H,48,55,56)	BEBXTZTZHAHQSO-UHFFFAOYSA-N	96986	3-(5-(4-((7-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)piperazin- 1-yl)-3-methyl-1H-indazol-1- yl)piperidine-2,6-dione::US20260000676, Compound A17	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96986	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96986&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2469161	164038230							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130641	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCN(c5ncc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cn5)CC3)CCN42)C(=O)N1	InChI=1S/C43H45N7O6/c51-31-6-7-32-37(17-31)56-25-34(27-4-2-1-3-5-27)40(32)29-19-44-43(45-20-29)48-12-10-26(11-13-48)21-47-14-15-49-30(23-47)24-55-38-18-33-28(16-36(38)49)22-50(42(33)54)35-8-9-39(52)46-41(35)53/h1-7,16-20,26,30,34-35,40,51H,8-15,21-25H2,(H,46,52,53)	ZLOPFKOIACXTPD-UHFFFAOYSA-N	96987	3-((S)-3-((1-(5-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)pyrimidin-2- yl)piperidin-4-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A18	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96987	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96987&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2603763	164038231							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130642	O=C1CCC(N2Cc3c(ccc4c3OC[C@@H]3CN(CC5CCN(c6ncc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cn6)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C43H45N7O6/c51-30-6-7-32-37(18-30)55-25-34(27-4-2-1-3-5-27)39(32)28-19-44-43(45-20-28)48-14-12-26(13-15-48)21-47-16-17-49-29(22-47)24-56-40-33-23-50(36-10-11-38(52)46-41(36)53)42(54)31(33)8-9-35(40)49/h1-9,18-20,26,29,34,36,39,51H,10-17,21-25H2,(H,46,52,53)	RPFWZHFAZYZAOK-UHFFFAOYSA-N	96988	3-((S)-7-((1-(5-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)pyrimidin-2- yl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A19	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96988	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96988&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2091399	164038232							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130643	O=C1CCC(N2Cc3c(ccc4c3OC[C@@H]3CN(CC5CCN(c6ncc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cn6)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C43H45N7O6/c51-30-6-7-32-37(18-30)55-25-34(27-4-2-1-3-5-27)39(32)28-19-44-43(45-20-28)48-14-12-26(13-15-48)21-47-16-17-49-29(22-47)24-56-40-33-23-50(36-10-11-38(52)46-41(36)53)42(54)31(33)8-9-35(40)49/h1-9,18-20,26,29,34,36,39,51H,10-17,21-25H2,(H,46,52,53)	RPFWZHFAZYZAOK-UHFFFAOYSA-N	96989	3-((S)-7-((1-(5-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)pyrimidin-2- yl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A20	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96989	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96989&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2368463	164038233							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130644	O=C1CCC(N2Cc3c(ccc4c3OC[C@@H]3CN(CC5CC6(CCN(c7ccc([C@H]8c9ccc(O)cc9OC[C@H]8c8ccccc8)cc7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O6/c54-35-10-11-37-42(22-35)58-29-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-18-16-48(17-19-51)23-30(24-48)25-50-20-21-52-34(26-50)28-59-45-38-27-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	SSNYEZAYMZGQKT-UHFFFAOYSA-N	96990	3-((S)-7-((7-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A21	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96990	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96990&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2086196	164038234							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130645	O=C1CCC(N2Cc3c(ccc4c3OC[C@@H]3CN(CC5CC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cc7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O6/c54-35-10-11-37-42(22-35)58-29-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-18-16-48(17-19-51)23-30(24-48)25-50-20-21-52-34(26-50)28-59-45-38-27-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	SSNYEZAYMZGQKT-UHFFFAOYSA-N	96991	3-((S)-7-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A22	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96991&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			3504598	164038235							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130646	COc1cccc([C@H]2COc3cc(O)ccc3[C@H]2c2ccc(N3CCC(CN4CCN5c6ccc7c(c6OC[C@@H]5C4)CN(C4CCC(=O)NC4=O)C7=O)CC3)cc2)c1	InChI=1S/C46H49N5O7/c1-56-34-4-2-3-30(21-34)38-27-57-41-22-33(52)9-10-36(41)43(38)29-5-7-31(8-6-29)49-17-15-28(16-18-49)23-48-19-20-50-32(24-48)26-58-44-37-25-51(40-13-14-42(53)47-45(40)54)46(55)35(37)11-12-39(44)50/h2-12,21-22,28,32,38,40,43,52H,13-20,23-27H2,1H3,(H,47,53,54)	OTLGVHCCZYBXFT-UHFFFAOYSA-N	96992	3-((S)-7-((1-(4-((3S,4R)-7-hydroxy-3-(3- methoxyphenyl)chroman-4- yl)phenyl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A23	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96992	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96992&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			915071	164038236							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130647	COc1cccc([C@@H]2COc3cc(O)ccc3[C@@H]2c2ccc(N3CCC(CN4CCN5c6ccc7c(c6OC[C@@H]5C4)CN(C4CCC(=O)NC4=O)C7=O)CC3)cc2)c1	InChI=1S/C46H49N5O7/c1-56-34-4-2-3-30(21-34)38-27-57-41-22-33(52)9-10-36(41)43(38)29-5-7-31(8-6-29)49-17-15-28(16-18-49)23-48-19-20-50-32(24-48)26-58-44-37-25-51(40-13-14-42(53)47-45(40)54)46(55)35(37)11-12-39(44)50/h2-12,21-22,28,32,38,40,43,52H,13-20,23-27H2,1H3,(H,47,53,54)	OTLGVHCCZYBXFT-UHFFFAOYSA-N	96993	3-((S)-7-((1-(4-((3R,4S)-7-hydroxy-3-(3- methoxyphenyl)chroman-4- yl)phenyl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A24	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96993	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96993&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			950371	164038237							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130648	Cc1nn(C2CCC(=O)NC2=O)c2ccc(N3CCN(CC4CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CC3)cc12	InChI=1S/C47H52N6O4/c1-31-39-25-36(11-14-41(39)53(49-31)42-15-16-44(55)48-46(42)56)52-23-21-50(22-24-52)29-32-27-47(28-32)17-19-51(20-18-47)35-9-7-34(8-10-35)45-38-13-12-37(54)26-43(38)57-30-40(45)33-5-3-2-4-6-33/h2-14,25-26,32,40,42,45,54H,15-24,27-30H2,1H3,(H,48,55,56)	BEBXTZTZHAHQSO-UHFFFAOYSA-N	96994	3-(5-(4-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)piperazin- 1-yl)-3-methyl-1H-indazol-1- yl)piperidine-2,6-dione::US20260000676, Compound A25	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96994	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96994&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			91899621	164038238							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130649	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CC3(CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC3)C2)C4)C(=O)N1	InChI=1S/C45H43N5O7/c51-32-10-11-33-38(20-32)57-24-36(27-4-2-1-3-5-27)41(33)28-6-8-31(9-7-28)48-16-14-45(15-17-48)25-49(26-45)40(53)23-47-21-29-18-34-35(19-30(29)22-47)44(56)50(43(34)55)37-12-13-39(52)46-42(37)54/h1-11,18-20,36-37,41,51H,12-17,21-26H2,(H,46,52,54)	JPEBSIKGHPZPGX-UHFFFAOYSA-N	96995	2-(2,6-dioxopiperidin-3-yl)-6-(2-(7-(4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-2,7-diazaspiro[3.5]nonan-2-yl)- 2-oxoethyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A26	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96995	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96995&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			691782	164038239							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130650	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-29-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-16-14-48(15-17-51)23-30(24-48)25-50-18-19-52-35(27-50)28-58-43-22-38-33(20-41(43)52)26-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	JGUADLWFBMOXGP-UHFFFAOYSA-N	96996	3-((S)-3-((7-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A27	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96996	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96996&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			3781132	164038240							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130651	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-29-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-16-14-48(15-17-51)23-30(24-48)25-50-18-19-52-35(27-50)28-58-43-22-38-33(20-41(43)52)26-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	JGUADLWFBMOXGP-UHFFFAOYSA-N	96997	3-((S)-3-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A28	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96997	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96997&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2745731	164038241							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130652	O=C1CCC(Nc2ccc(N3CCN(CC4CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5F)CC4)CC3)c(F)c2)C(=O)N1	InChI=1S/C42H45F2N5O4/c43-34-22-29(41-32-9-8-31(50)24-39(32)53-26-33(41)28-4-2-1-3-5-28)6-11-37(34)48-16-14-27(15-17-48)25-47-18-20-49(21-19-47)38-12-7-30(23-35(38)44)45-36-10-13-40(51)46-42(36)52/h1-9,11-12,22-24,27,33,36,41,45,50H,10,13-21,25-26H2,(H,46,51,52)	XONHEANMPMHLIL-UHFFFAOYSA-N	96998	3-((3-fluoro-4-(4-((1-(2-fluoro-4-((3S,4R)- 7-hydroxy-3-phenylchroman-4- yl)phenyl)piperidin-4-yl)methyl)piperazin- 1-yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A29	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96998	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96998&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			8646	164038242							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130653	O=C1CCC(Nc2ccc(N3CCN(CC4CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC4)CC3)c(F)c2)C(=O)N1	InChI=1S/C42H46FN5O4/c43-36-24-31(44-37-13-15-40(50)45-42(37)51)8-14-38(36)48-22-20-46(21-23-48)26-28-16-18-47(19-17-28)32-9-6-30(7-10-32)41-34-12-11-33(49)25-39(34)52-27-35(41)29-4-2-1-3-5-29/h1-12,14,24-25,28,35,37,41,44,49H,13,15-23,26-27H2,(H,45,50,51)	JSPQHEGDRJAZKU-UHFFFAOYSA-N	96999	3-((3-fluoro-4-(4-((1-(4-((3S,4R)-7- hydroxy-3-phenylchroman-4- yl)phenyl)piperidin-4-yl)methyl)piperazin- 1-yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A30	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96999	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96999&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			6463249	164038243							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130654	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CCC3(CC2)CCN(c2ccc([C@@H]5c6ccc(O)cc6OC[C@@H]5c5ccccc5)cc2)CC3)C4)C(=O)N1	InChI=1S/C47H47N5O7/c53-34-10-11-35-40(24-34)59-28-38(29-4-2-1-3-5-29)43(35)30-6-8-33(9-7-30)50-18-14-47(15-19-50)16-20-51(21-17-47)42(55)27-49-25-31-22-36-37(23-32(31)26-49)46(58)52(45(36)57)39-12-13-41(54)48-44(39)56/h1-11,22-24,38-39,43,53H,12-21,25-28H2,(H,48,54,56)	YDMQYRRRRMPTJD-UHFFFAOYSA-N	97000	2-(2,6-dioxopiperidin-3-yl)-6-(2-(9-(4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-3,9-diazaspiro[5.5]undecan-3- yl)-2-oxoethyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A31	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97000	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97000&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			816945	164038244							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130655	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(C(=O)CN2CC3(CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC3)C2)C4)C(=O)N1	InChI=1S/C45H43N5O7/c51-32-10-11-33-38(20-32)57-24-36(27-4-2-1-3-5-27)41(33)28-6-8-31(9-7-28)48-16-14-45(15-17-48)25-47(26-45)23-40(53)49-21-29-18-34-35(19-30(29)22-49)44(56)50(43(34)55)37-12-13-39(52)46-42(37)54/h1-11,18-20,36-37,41,51H,12-17,21-26H2,(H,46,52,54)	ZMDNGTWULHGEKN-UHFFFAOYSA-N	97001	2-(2,6-dioxopiperidin-3-yl)-6-(2-(7-(4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-2,7-diazaspiro[3.5]nonan-2- yl)acetyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A32	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97001	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97001&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			91899622	164038245							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130656	COc1cccc([C@H]2COc3cc(O)ccc3[C@H]2c2ccc(N3CCC(CN4CCN5c6ccc7c(c6OC[C@H]5C4)CN(C4CCC(=O)NC4=O)C7=O)CC3)cc2)c1	InChI=1S/C46H49N5O7/c1-56-34-4-2-3-30(21-34)38-27-57-41-22-33(52)9-10-36(41)43(38)29-5-7-31(8-6-29)49-17-15-28(16-18-49)23-48-19-20-50-32(24-48)26-58-44-37-25-51(40-13-14-42(53)47-45(40)54)46(55)35(37)11-12-39(44)50/h2-12,21-22,28,32,38,40,43,52H,13-20,23-27H2,1H3,(H,47,53,54)	OTLGVHCCZYBXFT-UHFFFAOYSA-N	97002	3-((R)-7-((1-(4-((3S,4R)-7-hydroxy-3-(3- methoxyphenyl)chroman-4- yl)phenyl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A33	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97002	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97002&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1162379	164038246							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130657	COc1cccc([C@@H]2COc3cc(O)ccc3[C@@H]2c2ccc(N3CCC(CN4CCN5c6ccc7c(c6OC[C@H]5C4)CN(C4CCC(=O)NC4=O)C7=O)CC3)cc2)c1	InChI=1S/C46H49N5O7/c1-56-34-4-2-3-30(21-34)38-27-57-41-22-33(52)9-10-36(41)43(38)29-5-7-31(8-6-29)49-17-15-28(16-18-49)23-48-19-20-50-32(24-48)26-58-44-37-25-51(40-13-14-42(53)47-45(40)54)46(55)35(37)11-12-39(44)50/h2-12,21-22,28,32,38,40,43,52H,13-20,23-27H2,1H3,(H,47,53,54)	OTLGVHCCZYBXFT-UHFFFAOYSA-N	97003	3-((R)-7-((1-(4-((3R,4S)-7-hydroxy-3-(3- methoxyphenyl)chroman-4- yl)phenyl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A34	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97003	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97003&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1940391	164038247							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130658	O=C1CCC(N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCN(c6ncc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cn6)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C43H45N7O6/c51-30-6-7-32-37(18-30)55-25-34(27-4-2-1-3-5-27)39(32)28-19-44-43(45-20-28)48-14-12-26(13-15-48)21-47-16-17-49-29(22-47)24-56-40-33-23-50(36-10-11-38(52)46-41(36)53)42(54)31(33)8-9-35(40)49/h1-9,18-20,26,29,34,36,39,51H,10-17,21-25H2,(H,46,52,53)	RPFWZHFAZYZAOK-UHFFFAOYSA-N	97004	3-((R)-7-((1-(5-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)pyrimidin-2- yl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- elisoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A35	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97004	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97004&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			3453546	164038248							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130659	O=C1CCC(N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCN(c6ncc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cn6)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C43H45N7O6/c51-30-6-7-32-37(18-30)55-25-34(27-4-2-1-3-5-27)39(32)28-19-44-43(45-20-28)48-14-12-26(13-15-48)21-47-16-17-49-29(22-47)24-56-40-33-23-50(36-10-11-38(52)46-41(36)53)42(54)31(33)8-9-35(40)49/h1-9,18-20,26,29,34,36,39,51H,10-17,21-25H2,(H,46,52,53)	RPFWZHFAZYZAOK-UHFFFAOYSA-N	97006	3-((R)-7-((1-(5-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)pyrimidin-2- yl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A36	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97006	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97006&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			430132	164038250							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130660	O=C1CC[C@H](N2Cc3c(ccc4c3OC[C@H]3CN(CC5CC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cc7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O6/c54-35-10-11-37-42(22-35)58-29-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-18-16-48(17-19-51)23-30(24-48)25-50-20-21-52-34(26-50)28-59-45-38-27-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	SSNYEZAYMZGQKT-UHFFFAOYSA-N	97007	(S)-3-((R)-7-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A37	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97007	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97007&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			100472	164038251					C17720		2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130661	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CCC3(CC2)CN(c2ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc2)C3)C4)C(=O)N1	InChI=1S/C45H43N5O7/c51-32-10-11-33-38(20-32)57-24-36(27-4-2-1-3-5-27)41(33)28-6-8-31(9-7-28)49-25-45(26-49)14-16-48(17-15-45)40(53)23-47-21-29-18-34-35(19-30(29)22-47)44(56)50(43(34)55)37-12-13-39(52)46-42(37)54/h1-11,18-20,36-37,41,51H,12-17,21-26H2,(H,46,52,54)	BXVMSRJPFSOBKE-UHFFFAOYSA-N	97008	2-(2,6-dioxopiperidin-3-yl)-6-(2-(2-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-2,7-diazaspiro[3.5]nonan-7-yl)- 2-oxoethyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A38	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97008	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97008&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2082778	164038252							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130662	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CC3(CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC3)C2)C4)C(=O)N1	InChI=1S/C45H43N5O7/c51-32-10-11-33-38(20-32)57-24-36(27-4-2-1-3-5-27)41(33)28-6-8-31(9-7-28)48-16-14-45(15-17-48)25-49(26-45)40(53)23-47-21-29-18-34-35(19-30(29)22-47)44(56)50(43(34)55)37-12-13-39(52)46-42(37)54/h1-11,18-20,36-37,41,51H,12-17,21-26H2,(H,46,52,54)	JPEBSIKGHPZPGX-UHFFFAOYSA-N	97009	2-(2,6-dioxopiperidin-3-yl)-6-(2-(7-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-2,7-diazaspiro[3.5]nonan-2-yl)- 2-oxoethyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A39	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97009	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97009&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			6537694	164038253							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130663	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CCC3(CC2)CCN(c2ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc2)CC3)C4)C(=O)N1	InChI=1S/C47H47N5O7/c53-34-10-11-35-40(24-34)59-28-38(29-4-2-1-3-5-29)43(35)30-6-8-33(9-7-30)50-18-14-47(15-19-50)16-20-51(21-17-47)42(55)27-49-25-31-22-36-37(23-32(31)26-49)46(58)52(45(36)57)39-12-13-41(54)48-44(39)56/h1-11,22-24,38-39,43,53H,12-21,25-28H2,(H,48,54,56)	YDMQYRRRRMPTJD-UHFFFAOYSA-N	97010	2-(2,6-dioxopiperidin-3-yl)-6-(2-(9-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-3,9-diazaspiro[5.5]undecan-3- yl)-2-oxoethyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A40	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97010	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97010&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1854166	164038254							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130664	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CCC3(CC2)CCN(c2ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc2)CC3)C4)C(=O)N1	InChI=1S/C47H49N5O6/c53-36-10-11-37-41(24-36)58-29-39(30-4-2-1-3-5-30)44(37)31-6-8-35(9-7-31)50-20-16-47(17-21-50)14-18-49(19-15-47)28-43(55)51-25-32-22-34-27-52(40-12-13-42(54)48-45(40)56)46(57)38(34)23-33(32)26-51/h1-11,22-24,39-40,44,53H,12-21,25-29H2,(H,48,54,56)	WFNJFSDLQSHAAO-UHFFFAOYSA-N	97011	(R)-3-(6-(2-(9-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-3,9- diazaspiro[5.5]undecan-3-yl)acetyl)-1- oxo-3,5,6,7-tetrahydropyrrolo[3,4- f]isoindol-2(1H)-yl)piperidine-2,6-dione::US20260000676, Compound A41	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97011	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97011&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			5454863	164038255							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130665	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CCC3(CC2)CCN(c2ccc([C@@H]5c6ccc(O)cc6OC[C@@H]5c5ccccc5)cc2)CC3)C4)C(=O)N1	InChI=1S/C47H49N5O6/c53-36-10-11-37-41(24-36)58-29-39(30-4-2-1-3-5-30)44(37)31-6-8-35(9-7-31)50-20-16-47(17-21-50)14-18-49(19-15-47)28-43(55)51-25-32-22-34-27-52(40-12-13-42(54)48-45(40)56)46(57)38(34)23-33(32)26-51/h1-11,22-24,39-40,44,53H,12-21,25-29H2,(H,48,54,56)	WFNJFSDLQSHAAO-UHFFFAOYSA-N	97012	3-(6-(2-(9-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-3,9- diazaspiro[5.5]undecan-3-yl)acetyl)-1- oxo-3,5,6,7-tetrahydropyrrolo[3,4- f]isoindol-2(1H)-yl)piperidine-2,6-dione::US20260000676, Compound A42	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97012	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97012&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			978078	164038256							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130666	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CCC3(CC2)CCN(c2ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc2)CC3)C4)C(=O)N1	InChI=1S/C47H49N5O6/c53-36-10-11-37-41(24-36)58-29-39(30-4-2-1-3-5-30)44(37)31-6-8-35(9-7-31)50-20-16-47(17-21-50)14-18-49(19-15-47)28-43(55)51-25-32-22-34-27-52(40-12-13-42(54)48-45(40)56)46(57)38(34)23-33(32)26-51/h1-11,22-24,39-40,44,53H,12-21,25-29H2,(H,48,54,56)	WFNJFSDLQSHAAO-UHFFFAOYSA-N	97013	2-(2,6-dioxopiperidin-3-yl)-6-(2-(9-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-3,9-diazaspiro[5.5]undecan-3- yl)acetyl)-6,7-dihydropyrrolo[3,4- flisoindole-1,3(2H,5H)-dione::US20260000676, Compound A43	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97013	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97013&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1218643	164038257							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130667	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CCC3(CC2)CN(c2ccc([C@@H]5c6ccc(O)cc6OC[C@@H]5c5ccccc5)cc2)C3)C4)C(=O)N1	InChI=1S/C45H43N5O7/c51-32-10-11-33-38(20-32)57-24-36(27-4-2-1-3-5-27)41(33)28-6-8-31(9-7-28)49-25-45(26-49)14-16-48(17-15-45)40(53)23-47-21-29-18-34-35(19-30(29)22-47)44(56)50(43(34)55)37-12-13-39(52)46-42(37)54/h1-11,18-20,36-37,41,51H,12-17,21-26H2,(H,46,52,54)	BXVMSRJPFSOBKE-UHFFFAOYSA-N	97014	2-(2,6-dioxopiperidin-3-yl)-6-(2-(2-(4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-2,7-diazaspiro[3.5]nonan-7-yl)- 2-oxoethyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A44	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97014&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2586218	164038258							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130668	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CC3(CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC3)C2)C4)C(=O)N1	InChI=1S/C45H45N5O6/c51-34-10-11-35-39(20-34)56-25-37(28-4-2-1-3-5-28)42(35)29-6-8-33(9-7-29)48-16-14-45(15-17-48)26-47(27-45)24-41(53)49-21-30-18-32-23-50(38-12-13-40(52)46-43(38)54)44(55)36(32)19-31(30)22-49/h1-11,18-20,37-38,42,51H,12-17,21-27H2,(H,46,52,54)	RNNMVVNAVASCCO-UHFFFAOYSA-N	97015	3-(6-(2-(7-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2,7- diazaspiro[3.5]nonan-2-yl)acetyl)-1-oxo- 3,5,6,7-tetrahydropyrrolo[3,4-f]isoindol- 2(1H)-yl)piperidine-2,6-dione::US20260000676, Compound A45	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97015	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97015&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			24979598	164038259							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130669	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CCC3(CC2)CN(c2ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc2)C3)C4)C(=O)N1	InChI=1S/C45H45N5O6/c51-34-10-11-35-39(20-34)56-25-37(28-4-2-1-3-5-28)42(35)29-6-8-33(9-7-29)49-26-45(27-49)14-16-47(17-15-45)24-41(53)48-21-30-18-32-23-50(38-12-13-40(52)46-43(38)54)44(55)36(32)19-31(30)22-48/h1-11,18-20,37-38,42,51H,12-17,21-27H2,(H,46,52,54)	YIVSKZUSEWEYQU-UHFFFAOYSA-N	97016	2-(2,6-dioxopiperidin-3-yl)-6-(2-(2-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-2,7-diazaspiro[3.5]nonan-7- yl)acetyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A46	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97016	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97016&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			7277818	164038260							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130670	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CCC3(CC2)CN(c2ccc([C@@H]5c6ccc(O)cc6OC[C@@H]5c5ccccc5)cc2)C3)C4)C(=O)N1	InChI=1S/C45H45N5O6/c51-34-10-11-35-39(20-34)56-25-37(28-4-2-1-3-5-28)42(35)29-6-8-33(9-7-29)49-26-45(27-49)14-16-47(17-15-45)24-41(53)48-21-30-18-32-23-50(38-12-13-40(52)46-43(38)54)44(55)36(32)19-31(30)22-48/h1-11,18-20,37-38,42,51H,12-17,21-27H2,(H,46,52,54)	YIVSKZUSEWEYQU-UHFFFAOYSA-N	97017	2-(2,6-dioxopiperidin-3-yl)-6-(2-(2-(4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-2,7-diazaspiro[3.5]nonan-7- yl)acetyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A47	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97017	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97017&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			16289623	164038261							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130671	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CCC3(CC2)CN(c2ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc2)C3)C4)C(=O)N1	InChI=1S/C45H45N5O6/c51-34-10-11-35-39(20-34)56-25-37(28-4-2-1-3-5-28)42(35)29-6-8-33(9-7-29)49-26-45(27-49)14-16-47(17-15-45)24-41(53)48-21-30-18-32-23-50(38-12-13-40(52)46-43(38)54)44(55)36(32)19-31(30)22-48/h1-11,18-20,37-38,42,51H,12-17,21-27H2,(H,46,52,54)	YIVSKZUSEWEYQU-UHFFFAOYSA-N	97018	3-(6-(2-(2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2,7- diazaspiro[3.5 ]nonan-7-yl)acetyl)-1-oxo- 3,5,6,7-tetrahydropyrrolo[3,4-f]isoindol- 2(1H)-yl)piperidine-2,6-dione::US20260000676, Compound A48	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97018	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97018&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			16302071	164038262							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130672	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CCC3(CC2)CN(c2ccc([C@@H]5c6ccc(O)cc6OC[C@@H]5c5ccccc5)cc2)C3)C4)C(=O)N1	InChI=1S/C45H45N5O6/c51-34-10-11-35-39(20-34)56-25-37(28-4-2-1-3-5-28)42(35)29-6-8-33(9-7-29)49-26-45(27-49)14-16-47(17-15-45)24-41(53)48-21-30-18-32-23-50(38-12-13-40(52)46-43(38)54)44(55)36(32)19-31(30)22-48/h1-11,18-20,37-38,42,51H,12-17,21-27H2,(H,46,52,54)	YIVSKZUSEWEYQU-UHFFFAOYSA-N	97019	3-(6-(2-(2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2,7- diazaspiro[3.5]nonan-7-yl)acetyl)-1-oxo- 3,5,6,7-tetrahydropyrrolo[3,4-f]isoindol- 2(1H)-yl)piperidine-2,6-dione::US20260000676, Compound A49	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97019	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97019&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2482686	164038263							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130673	O=C1CC[C@H](N2Cc3c(ccc4c3OC[C@H]3CN(CC5CC6(CCN(c7ccc([C@H]8c9ccc(O)cc9OC[C@H]8c8ccccc8)cc7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O6/c54-35-10-11-37-42(22-35)58-29-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-18-16-48(17-19-51)23-30(24-48)25-50-20-21-52-34(26-50)28-59-45-38-27-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	SSNYEZAYMZGQKT-UHFFFAOYSA-N	97021	(S)-3-((R)-7-((7-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A50	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97021&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			28803	164038265							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130674	O=C1CCC(Nc2ccc(N3CCN(CC4CC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C4)CC3)c(F)c2)C(=O)N1	InChI=1S/C45H50FN5O4/c46-38-24-33(47-39-13-15-42(53)48-44(39)54)8-14-40(38)51-22-20-49(21-23-51)28-30-26-45(27-30)16-18-50(19-17-45)34-9-6-32(7-10-34)43-36-12-11-35(52)25-41(36)55-29-37(43)31-4-2-1-3-5-31/h1-12,14,24-25,30,37,39,43,47,52H,13,15-23,26-29H2,(H,48,53,54)	WOTXGZLKWHJECJ-UHFFFAOYSA-N	97022	3-((3-fluoro-4-(4-((7-(4-((3R,4S)-7- hydroxy-3-phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)piperazin- 1-yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A51	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97022	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97022&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			44263771	164038266							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130675	O=C1CCC(Nc2ccc(N3CCN(CC4CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OCC7c7ccccc7)cc6)CC5)C4)CC3)c(F)c2)C(=O)N1	InChI=1S/C45H50FN5O4/c46-38-24-33(47-39-13-15-42(53)48-44(39)54)8-14-40(38)51-22-20-49(21-23-51)28-30-26-45(27-30)16-18-50(19-17-45)34-9-6-32(7-10-34)43-36-12-11-35(52)25-41(36)55-29-37(43)31-4-2-1-3-5-31/h1-12,14,24-25,30,37,39,43,47,52H,13,15-23,26-29H2,(H,48,53,54)	WOTXGZLKWHJECJ-UHFFFAOYSA-N	97023	3-((3-fluoro-4-(4-((7-(4-((3S,4R)-7- hydroxy-3-phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)piperazin- 1-yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A52	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97023	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97023&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1534928	164038267							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130676	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCC5(CC3)CN(c3ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc3)C5)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-27-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-28-48(29-51)16-14-30(15-17-48)23-50-18-19-52-35(25-50)26-58-43-22-38-33(20-41(43)52)24-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	IKGGCVYEWPPTHT-UHFFFAOYSA-N	97024	3-((S)-3-((2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A53	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97024	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97024&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			22694	164038268							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130677	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(C(=O)CN2CCC3(CC2)CCN(c2ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc2)CC3)C4)C(=O)N1	InChI=1S/C47H47N5O7/c53-34-10-11-35-40(24-34)59-28-38(29-4-2-1-3-5-29)43(35)30-6-8-33(9-7-30)50-20-16-47(17-21-50)14-18-49(19-15-47)27-42(55)51-25-31-22-36-37(23-32(31)26-51)46(58)52(45(36)57)39-12-13-41(54)48-44(39)56/h1-11,22-24,38-39,43,53H,12-21,25-28H2,(H,48,54,56)	CHXFLTHETNYWSI-UHFFFAOYSA-N	97025	2-(2,6-dioxopiperidin-3-yl)-6-(2-(9-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-3,9-diazaspiro[5.5]undecan-3- yl)acetyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione formate::US20260000676, Compound A54	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97025	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97025&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			3034525	164038269							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130678	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(C(=O)CN2CC3(CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC3)C2)C4)C(=O)N1	InChI=1S/C45H43N5O7/c51-32-10-11-33-38(20-32)57-24-36(27-4-2-1-3-5-27)41(33)28-6-8-31(9-7-28)48-16-14-45(15-17-48)25-47(26-45)23-40(53)49-21-29-18-34-35(19-30(29)22-49)44(56)50(43(34)55)37-12-13-39(52)46-42(37)54/h1-11,18-20,36-37,41,51H,12-17,21-26H2,(H,46,52,54)	ZMDNGTWULHGEKN-UHFFFAOYSA-N	97026	2-(2,6-dioxopiperidin-3-yl)-6-(2-(7-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-2,7-diazaspiro[3.5]nonan-2- yl)acetyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione formate::US20260000676, Compound A55	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97026	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97026&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			251983	164038270							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130679	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CC3(CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC3)C2)C4)C(=O)N1	InChI=1S/C45H45N5O6/c51-34-10-11-35-39(20-34)56-25-37(28-4-2-1-3-5-28)42(35)29-6-8-33(9-7-29)48-16-14-45(15-17-48)26-47(27-45)24-41(53)49-21-30-18-32-23-50(38-12-13-40(52)46-43(38)54)44(55)36(32)19-31(30)22-49/h1-11,18-20,37-38,42,51H,12-17,21-27H2,(H,46,52,54)	RNNMVVNAVASCCO-UHFFFAOYSA-N	97027	3-(6-(2-(7-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2,7- diazaspiro[3.5]nonan-2-yl)acetyl)-1-oxo- 3,5,6,7-tetrahydropyrrolo[3,4-f]isoindol- 2(1H)-yl)piperidine-2,6-dione formate::US20260000676, Compound A56	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97027&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			270861	164038271							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130680	CC(C(=O)N1Cc2cc3c(cc2C1)C(=O)N(C1CCC(=O)NC1=O)C3=O)N1CCC2(CCN(c3ccc([C@H]4c5ccc(O)cc5OC[C@H]4c4ccccc4)cc3)CC2)CC1	InChI=1S/C48H49N5O7/c1-29(45(57)52-26-32-23-37-38(24-33(32)27-52)47(59)53(46(37)58)40-13-14-42(55)49-44(40)56)50-19-15-48(16-20-50)17-21-51(22-18-48)34-9-7-31(8-10-34)43-36-12-11-35(54)25-41(36)60-28-39(43)30-5-3-2-4-6-30/h2-12,23-25,29,39-40,43,54H,13-22,26-28H2,1H3,(H,49,55,56)	FOZBXYHGNVUKNM-UHFFFAOYSA-N	97029	2-(2,6-dioxopiperidin-3-yl)-6-(2-(9-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-3,9-diazaspiro[5.5]undecan-3- yl)propanoyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A57	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97029	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97029&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			257272	164038273							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130681	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCC5(CC3)CN(c3ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc3)C5)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-27-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-28-48(29-51)16-14-30(15-17-48)23-50-18-19-52-35(25-50)26-58-43-22-38-33(20-41(43)52)24-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	IKGGCVYEWPPTHT-UHFFFAOYSA-N	97030	3-((S)-3-((2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A58	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97030	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97030&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			289018	164038274							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130682	O=C1CC[C@H](N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-29-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-16-14-48(15-17-51)23-30(24-48)25-50-18-19-52-35(27-50)28-58-43-22-38-33(20-41(43)52)26-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	JGUADLWFBMOXGP-UHFFFAOYSA-N	97031	(S)-3-((S)-3-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A59	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97031&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			498990	164038275							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130683	COC[C@H](C(=O)N1Cc2cc3c(cc2C1)C(=O)N(C1CCC(=O)NC1=O)C3)N1CCC2(CCN(c3ccc([C@@H]4c5ccc(O)cc5OC[C@@H]4c4ccccc4)cc3)CC2)CC1	InChI=1S/C49H53N5O7/c1-60-30-42(48(59)53-26-33-23-35-28-54(41-13-14-44(56)50-46(41)57)47(58)39(35)24-34(33)27-53)52-21-17-49(18-22-52)15-19-51(20-16-49)36-9-7-32(8-10-36)45-38-12-11-37(55)25-43(38)61-29-40(45)31-5-3-2-4-6-31/h2-12,23-25,40-42,45,55H,13-22,26-30H2,1H3,(H,50,56,57)	ROYIWWJGHAIZCB-UHFFFAOYSA-N	97033	3-(6-((R)-2-(9-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-3,9- diazaspiro[5.5]undecan-3-yl)-3- methoxypropanoyl)-1-oxo-3,5,6,7- tetrahydropyrrolo[3,4-f]isoindol-2(1H)- yl)piperidine-2,6-dione::US20260000676, Compound A60	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97033	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97033&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			386510	164038277							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130684	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cn5)CC3)CCN42)C(=O)N1	InChI=1S/C44H46N6O6/c51-32-7-8-33-38(19-32)56-26-35(28-4-2-1-3-5-28)42(33)29-6-10-40(45-21-29)48-14-12-27(13-15-48)22-47-16-17-49-31(24-47)25-55-39-20-34-30(18-37(39)49)23-50(44(34)54)36-9-11-41(52)46-43(36)53/h1-8,10,18-21,27,31,35-36,42,51H,9,11-17,22-26H2,(H,46,52,53)	KEBZSMMIIUEDLD-UHFFFAOYSA-N	97034	3-((S)-3-((1-(5-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)pyridin-2- yl)piperidin-4-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A61	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97034	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97034&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			257275	164038278							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130685	O=C9CCC(N8Cc7cc(N6CCN(CC5CCN(c4ccc([C@@H]2c1ccc(O)cc1OC[C@@H]2c3ccccc3)cc4)CC5)CC6)ccc7C8=O)C(=O)N9	InChI=1S/C45H49N5O4/c1-30-7-16-41(44(52)46-30)50-28-34-25-36(12-14-38(34)45(50)53)49-23-21-47(22-24-49)27-31-17-19-48(20-18-31)35-10-8-33(9-11-35)43-39-15-13-37(51)26-42(39)54-29-40(43)32-5-3-2-4-6-32/h2-6,8-15,25-26,31,40-41,43,51H,1,7,16-24,27-29H2,(H,46,52)	QSRYPADAZHLZSE-UHFFFAOYSA-N	97035	3-(5-(4-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)piperazin-1-yl)-1-oxoisoindolin- 2-yl)piperidine-2,6-dione::US20260000676, Compound A62	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97035	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97035&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			280899	164038279							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130686	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCC5(CC3)CN(c3ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc3)C5)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-27-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-28-48(29-51)16-14-30(15-17-48)23-50-18-19-52-35(25-50)26-58-43-22-38-33(20-41(43)52)24-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	IKGGCVYEWPPTHT-UHFFFAOYSA-N	97036	3-((S)-3-((2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A63	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97036	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97036&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			44623872	164038280							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130687	O=C1CCC(N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cn6)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C44H46N6O6/c51-31-7-8-33-38(20-31)55-26-35(28-4-2-1-3-5-28)41(33)29-6-12-39(45-21-29)48-16-14-27(15-17-48)22-47-18-19-49-30(23-47)25-56-42-34-24-50(37-11-13-40(52)46-43(37)53)44(54)32(34)9-10-36(42)49/h1-10,12,20-21,27,30,35,37,41,51H,11,13-19,22-26H2,(H,46,52,53)	SHCBRAIXQDZAEO-UHFFFAOYSA-N	97037	3-((R)-7-((1-(5-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)pyridin-2- yl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A64	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97037	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97037&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			49778889	164038281					C06049		2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130688	O=C1CCC(C2Cc3c(ccc4c3OC[C@H]3CN(CC5CC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cn7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O6/c54-33-7-8-36-41(20-33)58-28-39(30-4-2-1-3-5-30)44(36)31-6-12-42(49-24-31)52-16-14-48(15-17-52)22-29(23-48)25-51-18-19-53-32(26-51)27-59-46-38-21-37(35-10-13-43(55)50-47(35)57)45(56)34(38)9-11-40(46)53/h1-9,11-12,20,24,29,32,35,37,39,44,54H,10,13-19,21-23,25-28H2,(H,50,55,57)	OLIMOMUHMQFDSE-UHFFFAOYSA-N	97038	3-((R)-7-((7-(5-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)pyridin-2-yl)-7- azaspiro[3.5]nonan-2-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A65	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97038	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97038&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			49786875	164038282							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130689	O=C1CCC(N2Cc3cc(N4CCN(CC5CC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cn7)CC6)C5)CC4)ccc3C2=O)C(=O)N1	InChI=1S/C46H50N6O5/c53-35-8-10-37-40(23-35)57-29-38(31-4-2-1-3-5-31)43(37)32-6-12-41(47-26-32)51-16-14-46(15-17-51)24-30(25-46)27-49-18-20-50(21-19-49)34-7-9-36-33(22-34)28-52(45(36)56)39-11-13-42(54)48-44(39)55/h1-10,12,22-23,26,30,38-39,43,53H,11,13-21,24-25,27-29H2,(H,48,54,55)	MOXUHRVGVLTQQM-UHFFFAOYSA-N	97039	3-(5-(4-((7-(5-((3S,4R)-7-hydoxy-3- phenylchroman-4-yl)pyridin-2-yl)-7-azaspiro [3.5]nonan-2-yl)methyl)piperazin-1-yl)-1- oxoisoindolin-2-yl)piperidine-2,6-dione::US20260000676, Compound A67	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97039&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			49789705	164038283					C06049		2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130690	O=C1CCC(N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cn6)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C44H46N6O6/c51-31-7-8-33-38(20-31)55-26-35(28-4-2-1-3-5-28)41(33)29-6-12-39(45-21-29)48-16-14-27(15-17-48)22-47-18-19-49-30(23-47)25-56-42-34-24-50(37-11-13-40(52)46-43(37)53)44(54)32(34)9-10-36(42)49/h1-10,12,20-21,27,30,35,37,41,51H,11,13-19,22-26H2,(H,46,52,53)	SHCBRAIXQDZAEO-UHFFFAOYSA-N	97040	3-((R)-7-((1-(5-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)pyridin-2- yl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A69	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97040	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97040&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			49790045	164038284					C06049		2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130691	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cn5)CC3)CCN42)C(=O)N1	InChI=1S/C44H46N6O6/c51-32-7-8-33-38(19-32)56-26-35(28-4-2-1-3-5-28)42(33)29-6-10-40(45-21-29)48-14-12-27(13-15-48)22-47-16-17-49-31(24-47)25-55-39-20-34-30(18-37(39)49)23-50(44(34)54)36-9-11-41(52)46-43(36)53/h1-8,10,18-21,27,31,35-36,42,51H,9,11-17,22-26H2,(H,46,52,53)	KEBZSMMIIUEDLD-UHFFFAOYSA-N	97041	3-((S)-3-((1-(5-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)pyridin-2- yl)piperidin-4-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A70	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97041	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97041&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			49790107	164038285							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130692	O=C1CCC(N2Cc3cc4c(cc3C2=O)OCC42CCN(CC3CC4(CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC4)C3)CC2)C(=O)N1	InChI=1S/C49H52N4O6/c54-36-10-11-37-42(23-36)58-29-39(32-4-2-1-3-5-32)45(37)33-6-8-35(9-7-33)52-20-14-48(15-21-52)25-31(26-48)27-51-18-16-49(17-19-51)30-59-43-24-38-34(22-40(43)49)28-53(47(38)57)41-12-13-44(55)50-46(41)56/h1-11,22-24,31,39,41,45,54H,12-21,25-30H2,(H,50,55,56)	SFYAXZBCMIFZJQ-UHFFFAOYSA-N	97042	3-(1'-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-7-oxo- 5,7-dihydro-2H,6H-spiro[furo[2,3- f]isoindole-3,4'-piperidin]-6-yl)piperidine- 2,6-dione::US20260000676, Compound A71	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97042	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97042&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			9503678	164038286							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130693	O=C1CCC(Nc2ccc(C3CCN(CC4CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC4)CC3)c(F)c2)C(=O)N1	InChI=1S/C43H47FN4O4/c44-38-24-32(45-39-14-15-41(50)46-43(39)51)8-12-35(38)30-18-20-47(21-19-30)26-28-16-22-48(23-17-28)33-9-6-31(7-10-33)42-36-13-11-34(49)25-40(36)52-27-37(42)29-4-2-1-3-5-29/h1-13,24-25,28,30,37,39,42,45,49H,14-23,26-27H2,(H,46,50,51)	NZYGULYNVUCXSA-UHFFFAOYSA-N	97043	3-((3-fluoro-4-(1-((1-(4-((3S,4R)-7- hydroxy-3-phenylchroman-4- yl)phenyl)piperidin-4-yl)methyl)piperidin- 4-yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A72	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97043	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97043&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			331023	164038287							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130694	Cn1c(=O)n(C2CCC(=O)NC2=O)c2ccc(C3CCN(CC4CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CC3)cc21	InChI=1S/C48H53N5O5/c1-50-42-25-35(9-14-40(42)53(47(50)57)41-15-16-44(55)49-46(41)56)32-17-21-51(22-18-32)29-31-27-48(28-31)19-23-52(24-20-48)36-10-7-34(8-11-36)45-38-13-12-37(54)26-43(38)58-30-39(45)33-5-3-2-4-6-33/h2-14,25-26,31-32,39,41,45,54H,15-24,27-30H2,1H3,(H,49,55,56)	TTXQEPBKOMFPPO-UHFFFAOYSA-N	97044	3-(5-(1-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)piperidin- 4-yl)-3-methyl-2-oxo-2,3-dihydro-1H- benzo[d]imidazol-1-yl)piperidine-2,6- dione::US20260000676, Compound A73	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97044	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97044&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			341816	164038288							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130695	COc1cc(N2CCC(CN3CCN4c5cc6c(cc5OC[C@H]4C3)C(=O)N(C3CCC(=O)NC3=O)C6)CC2)ccc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C46H49N5O7/c1-56-40-20-31(7-9-34(40)44-35-10-8-33(52)21-41(35)58-27-37(44)29-5-3-2-4-6-29)49-15-13-28(14-16-49)23-48-17-18-50-32(25-48)26-57-42-22-36-30(19-39(42)50)24-51(46(36)55)38-11-12-43(53)47-45(38)54/h2-10,19-22,28,32,37-38,44,52H,11-18,23-27H2,1H3,(H,47,53,54)	FAZUJCHEBBDOGY-UHFFFAOYSA-N	97045	3-((R)-3-((1-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A74	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97045	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97045&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	3G8	4W1W	342536	164038289							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130696	O=C1CCC(Nc2ccc(C3CCN(CC4CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CC3)c(F)c2)C(=O)N1	InChI=1S/C46H51FN4O4/c47-40-24-34(48-41-14-15-43(53)49-45(41)54)8-12-37(40)32-16-20-50(21-17-32)28-30-26-46(27-30)18-22-51(23-19-46)35-9-6-33(7-10-35)44-38-13-11-36(52)25-42(38)55-29-39(44)31-4-2-1-3-5-31/h1-13,24-25,30,32,39,41,44,48,52H,14-23,26-29H2,(H,49,53,54)	SRLBCPOYBLDFED-UHFFFAOYSA-N	97046	3-((3-fluoro-4-(1-((7-(4-((3S,4R)-7- hydroxy-3-phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)piperidin- 4-yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A75	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97046&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			51361256	164038290							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130697	COc1cc(N2CCC(CN3CCN4c5ccc6c(c5OC[C@H]4C3)CN(C3CCC(=O)NC3=O)C6=O)CC2)ccc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C46H49N5O7/c1-56-40-21-30(7-9-34(40)43-35-10-8-32(52)22-41(35)57-27-37(43)29-5-3-2-4-6-29)49-17-15-28(16-18-49)23-48-19-20-50-31(24-48)26-58-44-36-25-51(39-13-14-42(53)47-45(39)54)46(55)33(36)11-12-38(44)50/h2-12,21-22,28,31,37,39,43,52H,13-20,23-27H2,1H3,(H,47,53,54)	KFOQSSLNXOAYPF-UHFFFAOYSA-N	97047	3-((R)-7-((1-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- 81pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A76	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97047&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			51361435	164038291							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130698	COc1cc(N2CCC(CN3CCN4c5ccc6c(c5OC[C@H]4C3)CN(C3CCC(=O)NC3=O)C6=O)CC2)ccc1[C@@H]1c2ccc(O)cc2OC[C@@H]1c1ccccc1	InChI=1S/C46H49N5O7/c1-56-40-21-30(7-9-34(40)43-35-10-8-32(52)22-41(35)57-27-37(43)29-5-3-2-4-6-29)49-17-15-28(16-18-49)23-48-19-20-50-31(24-48)26-58-44-36-25-51(39-13-14-42(53)47-45(39)54)46(55)33(36)11-12-38(44)50/h2-12,21-22,28,31,37,39,43,52H,13-20,23-27H2,1H3,(H,47,53,54)	KFOQSSLNXOAYPF-UHFFFAOYSA-N	97048	3-((R)-7-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A77	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97048&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			51361437	164038292							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130699	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(C(=O)C2CCN(C3CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC3)CC2)C4)C(=O)N1	InChI=1S/C47H47N5O7/c53-35-10-11-36-41(24-35)59-27-39(28-4-2-1-3-5-28)43(36)29-6-8-33(9-7-29)50-20-16-34(17-21-50)49-18-14-30(15-19-49)45(56)51-25-31-22-37-38(23-32(31)26-51)47(58)52(46(37)57)40-12-13-42(54)48-44(40)55/h1-11,22-24,30,34,39-40,43,53H,12-21,25-27H2,(H,48,54,55)	TVPBIAGVNCZHCY-UHFFFAOYSA-N	97049	2-(2,6-dioxopiperidin-3-yl)-6-(1'-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-[1,4'-bipiperidine]-4-carbonyl)- 6,7-dihydropyrrolo[3,4-f]isoindole- 1,3(2H,5H)-dione::US20260000676, Compound A78	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97049	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97049&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			51361443	164038293							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130700	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(C(=O)C2CCN(C3CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC3)CC2)C4)C(=O)N1	InChI=1S/C47H47N5O7/c53-35-10-11-36-41(24-35)59-27-39(28-4-2-1-3-5-28)43(36)29-6-8-33(9-7-29)50-20-16-34(17-21-50)49-18-14-30(15-19-49)45(56)51-25-31-22-37-38(23-32(31)26-51)47(58)52(46(37)57)40-12-13-42(54)48-44(40)55/h1-11,22-24,30,34,39-40,43,53H,12-21,25-27H2,(H,48,54,55)	TVPBIAGVNCZHCY-UHFFFAOYSA-N	97050	2-(2,6-dioxopiperidin-3-yl)-6-(1'-(4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-[1,4'-bipiperidine]-4-carbonyl)- 6,7-dihydropyrrolo[3,4-f]isoindole- 1,3(2H,5H)-dione::US20260000676, Compound A79	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97050	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97050&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			51361444	164038294							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130701	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)C2CCN(C3CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC3)CC2)C4)C(=O)N1	InChI=1S/C47H49N5O6/c53-37-10-11-38-42(24-37)58-28-40(29-4-2-1-3-5-29)44(38)30-6-8-35(9-7-30)50-20-16-36(17-21-50)49-18-14-31(15-19-49)46(56)51-25-32-22-34-27-52(41-12-13-43(54)48-45(41)55)47(57)39(34)23-33(32)26-51/h1-11,22-24,31,36,40-41,44,53H,12-21,25-28H2,(H,48,54,55)	YJWSVXDJVCMWPI-UHFFFAOYSA-N	97051	3-(6-(1'-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-[1,4'- bipiperidine]-4-carbonyl)-1-oxo-3,5,6,7- tetrahydropyrrolo[3,4-f]isoindol-2(1H)- yl)piperidine-2,6-dione::US20260000676, Compound A80	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97051	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97051&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			50911044	164038295							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130702	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)C2CCN(C3CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC3)CC2)C4)C(=O)N1	InChI=1S/C47H49N5O6/c53-37-10-11-38-42(24-37)58-28-40(29-4-2-1-3-5-29)44(38)30-6-8-35(9-7-30)50-20-16-36(17-21-50)49-18-14-31(15-19-49)46(56)51-25-32-22-34-27-52(41-12-13-43(54)48-45(41)55)47(57)39(34)23-33(32)26-51/h1-11,22-24,31,36,40-41,44,53H,12-21,25-28H2,(H,48,54,55)	YJWSVXDJVCMWPI-UHFFFAOYSA-N	97052	3-(6-(1'-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-[1,4'- bipiperidine]-4-carbonyl)-1-oxo-3,5,6,7- tetrahydropyrrolo[3,4-f]isoindol-2(1H)- yl)piperidine-2,6-dione::US20260000676, Compound A81	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97052&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			53383134	164038296							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130703	O=C1CCN(c2ccc(N3CCN(CC4CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC4)CC3)cc2)C(=O)N1	InChI=1S/C41H45N5O4/c47-35-14-15-36-38(26-35)50-28-37(30-4-2-1-3-5-30)40(36)31-6-8-32(9-7-31)44-19-16-29(17-20-44)27-43-22-24-45(25-23-43)33-10-12-34(13-11-33)46-21-18-39(48)42-41(46)49/h1-15,26,29,37,40,47H,16-25,27-28H2,(H,42,48,49)	MYAPPUHZKDMOPF-UHFFFAOYSA-N	97053	1-(4-(4-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)piperazin-1- yl)phenyl)dihydropyrimidine- 2,4(1H,3H)-dione::US20260000676, Compound A82	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97053	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97053&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			47095113	164038297							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130704	O=C1CCN(c2ccc(N3CCN(CC4CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CC3)cc2)C(=O)N1	InChI=1S/C44H49N5O4/c50-37-14-15-38-40(26-37)53-30-39(32-4-2-1-3-5-32)42(38)33-6-8-34(9-7-33)47-20-17-44(18-21-47)27-31(28-44)29-46-22-24-48(25-23-46)35-10-12-36(13-11-35)49-19-16-41(51)45-43(49)52/h1-15,26,31,39,42,50H,16-25,27-30H2,(H,45,51,52)	OIYBINNRJUPUDP-UHFFFAOYSA-N	97054	1-(4-(4-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2- yl)methyl)piperazin-1- yl)phenyl)dihydropyrimidine- 2,4(1H,3H)-dione::US20260000676, Compound A83	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97054	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97054&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			60159929	164038298							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130705	COc1cc(N2CCC(CN3CCN4c5cc6c(cc5OC[C@H]4C3)C(=O)N(C3CCC(=O)NC3=O)C6)CC2)ccc1[C@@H]1c2ccc(O)cc2OC[C@@H]1c1ccccc1	InChI=1S/C46H49N5O7/c1-56-40-20-31(7-9-34(40)44-35-10-8-33(52)21-41(35)58-27-37(44)29-5-3-2-4-6-29)49-15-13-28(14-16-49)23-48-17-18-50-32(25-48)26-57-42-22-36-30(19-39(42)50)24-51(46(36)55)38-11-12-43(53)47-45(38)54/h2-10,19-22,28,32,37-38,44,52H,11-18,23-27H2,1H3,(H,47,53,54)	FAZUJCHEBBDOGY-UHFFFAOYSA-N	97055	3-((R)-3-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A84	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97055&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			646580	164038299							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130706	O=C1CCC(NC(=O)c2ccc(N3CCN(CC4CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CC3)cn2)C(=O)N1	InChI=1S/C45H50N6O5/c52-35-11-12-36-40(24-35)56-29-37(31-4-2-1-3-5-31)42(36)32-6-8-33(9-7-32)50-18-16-45(17-19-50)25-30(26-45)28-49-20-22-51(23-21-49)34-10-13-38(46-27-34)43(54)47-39-14-15-41(53)48-44(39)55/h1-13,24,27,30,37,39,42,52H,14-23,25-26,28-29H2,(H,47,54)(H,48,53,55)	JHQMFIGTTHYJPH-UHFFFAOYSA-N	97056	N-(2,6-dioxopiperidin-3-yl)-5-(4-((7-(4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-7-azaspiro[3.5]nonan-2- yl)methyl)piperazin-1-yl)picolinamide::US20260000676, Compound A85	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97056&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			649098	164038300							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130707	O=C1CCC(N2Cc3cc4c(cc3C2=O)OCC42CCN(CC3CCN(c4ccc([C@@H]5c6ccc(O)cc6OC[C@@H]5c5ccccc5)cc4)CC3)CC2)C(=O)N1	InChI=1S/C46H48N4O6/c51-34-10-11-35-40(23-34)55-27-37(30-4-2-1-3-5-30)43(35)31-6-8-33(9-7-31)49-18-14-29(15-19-49)25-48-20-16-46(17-21-48)28-56-41-24-36-32(22-38(41)46)26-50(45(36)54)39-12-13-42(52)47-44(39)53/h1-11,22-24,29,37,39,43,51H,12-21,25-28H2,(H,47,52,53)	UQHDAZNEGXGRDX-UHFFFAOYSA-N	97057	3-(1'-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)-7-oxo-5,7-dihydro-2H,6H- spiro[furo[2,3-f]isoindole-3,4'-piperidin]- 6-yl)piperidine-2,6-dione::US20260000676, Compound A86	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97057	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97057&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			264006	164038301							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130708	O=C1CCN(c2ccc(N3CCC(CN4CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CC3)cc2)C(=O)N1	InChI=1S/C44H49N5O4/c50-37-14-15-38-40(26-37)53-28-39(32-4-2-1-3-5-32)42(38)33-6-8-34(9-7-33)48-24-19-44(20-25-48)29-46(30-44)27-31-16-21-47(22-17-31)35-10-12-36(13-11-35)49-23-18-41(51)45-43(49)52/h1-15,26,31,39,42,50H,16-25,27-30H2,(H,45,51,52)	QRABZRCTKVZUIT-UHFFFAOYSA-N	97058	1-(4-(4-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2,7- diazaspiro[3.5]nonan-2- yl)methyl)piperidin-1- yl)phenyl)dihydropyrimidine- 2,4(1H,3H)-dione::US20260000676, Compound A87	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97058	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97058&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2736920	164038302							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130709	O=C1CCC(NC(=O)c2ccc(N3CCN(CC4CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC4)CC3)cn2)C(=O)N1	InChI=1S/C42H46N6O5/c49-33-11-12-34-38(24-33)53-27-35(29-4-2-1-3-5-29)40(34)30-6-8-31(9-7-30)47-18-16-28(17-19-47)26-46-20-22-48(23-21-46)32-10-13-36(43-25-32)41(51)44-37-14-15-39(50)45-42(37)52/h1-13,24-25,28,35,37,40,49H,14-23,26-27H2,(H,44,51)(H,45,50,52)	VSEHCADHYDAABF-UHFFFAOYSA-N	97059	N-(2,6-dioxopiperidin-3-yl)-5-(4-((1-(4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)piperidin-4-yl)methyl)piperazin- 1-yl)picolinamide::US20260000676, Compound A88	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97059	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97059&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			659242	164038303							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130710	O=C1CC[C@@H](N2Cc3c(ccc4c3OC[C@H]3CN(CC5CC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cc7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O6/c54-35-10-11-37-42(22-35)58-29-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-18-16-48(17-19-51)23-30(24-48)25-50-20-21-52-34(26-50)28-59-45-38-27-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	SSNYEZAYMZGQKT-UHFFFAOYSA-N	97060	(R)-3-((R)-7-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A89	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97060	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97060&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			659424	164038304							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130711	O=C1CC[C@H](N2Cc3c(ccc4c3OC[C@H]3CN(CC5CC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cc7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O6/c54-35-10-11-37-42(22-35)58-29-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-18-16-48(17-19-51)23-30(24-48)25-50-20-21-52-34(26-50)28-59-45-38-27-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	SSNYEZAYMZGQKT-UHFFFAOYSA-N	97061	(S)-3-((R)-7-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- c]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A90	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97061	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97061&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			660194	164038305							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130712	O=C1CCC(Nc2ccc3c(c2)OC[C@H]2CN(CC4CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC4)CCN32)C(=O)N1	InChI=1S/C43H47N5O5/c49-34-11-12-35-39(23-34)53-27-36(29-4-2-1-3-5-29)42(35)30-6-9-32(10-7-30)47-18-16-28(17-19-47)24-46-20-21-48-33(25-46)26-52-40-22-31(8-14-38(40)48)44-37-13-15-41(50)45-43(37)51/h1-12,14,22-23,28,33,36-37,42,44,49H,13,15-21,24-27H2,(H,45,50,51)	AMTBEGNKSBJTOX-UHFFFAOYSA-N	97062	3-(((R)-3-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)-1,2,3,4,4a,5- hexahydrobenzo[b]pyrazino[1,2- d][1,4]oxazin-8-yl)amino)piperidine-2,6- dione hydrochloride::US20260000676, Compound A91	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97062	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97062&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			660635	164038306							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130713	O=C1CCC(N2Cc3cc(N4CCN(CC5CC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cn7)CC6)C5)CC4)ccc3C2=O)C(=O)N1	InChI=1S/C46H50N6O5/c53-35-8-10-37-40(23-35)57-29-38(31-4-2-1-3-5-31)43(37)32-6-12-41(47-26-32)51-16-14-46(15-17-51)24-30(25-46)27-49-18-20-50(21-19-49)34-7-9-36-33(22-34)28-52(45(36)56)39-11-13-42(54)48-44(39)55/h1-10,12,22-23,26,30,38-39,43,53H,11,13-21,24-25,27-29H2,(H,48,54,55)	MOXUHRVGVLTQQM-UHFFFAOYSA-N	97063	(R)-3-(5-(4-((7-(5-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)pyridin-2-yl)-7- azaspiro[3.5]nonan-2- yl)methyl)piperazin-1-yl)-1- oxoisoindolin-2-yl)piperidine-2,6-dione::US20260000676, Compound A92	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97063	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97063&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			663629	164038307							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130714	O=C1CCC(NC(=O)c2ccc3c(n2)OCC2CN(CC4CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CCN32)C(=O)N1	InChI=1S/C46H50N6O6/c53-34-10-11-35-40(22-34)57-28-36(30-4-2-1-3-5-30)42(35)31-6-8-32(9-7-31)51-18-16-46(17-19-51)23-29(24-46)25-50-20-21-52-33(26-50)27-58-45-39(52)14-12-38(48-45)43(55)47-37-13-15-41(54)49-44(37)56/h1-12,14,22,29,33,36-37,42,53H,13,15-21,23-28H2,(H,47,55)(H,49,54,56)	RRVFSYQOALYMCA-UHFFFAOYSA-N	97064	(4aR)-N-(2,6-dioxopiperidin-3-yl)-3-((7- (4-((3S,4R)-7-hydroxy-3-phenylchroman- 4-yl)phenyl)-7-azaspiro[3.5]nonan-2- yl)methyl)-1,2,3,4,4a,5- hexahydropyrazino[1,2-d]pyrido[2,3- b][1,4]oxazine-8-carboxamide::US20260000676, Compound A93	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97064	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97064&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			663797	164038308							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130715	O=C1CCC(Nc2ccc3c(c2)OC[C@H]2CN(CC4CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CCN32)C(=O)N1	InChI=1S/C46H51N5O5/c52-36-11-12-37-41(23-36)56-29-38(31-4-2-1-3-5-31)44(37)32-6-9-34(10-7-32)50-18-16-46(17-19-50)24-30(25-46)26-49-20-21-51-35(27-49)28-55-42-22-33(8-14-40(42)51)47-39-13-15-43(53)48-45(39)54/h1-12,14,22-23,30,35,38-39,44,47,52H,13,15-21,24-29H2,(H,48,53,54)	FBBKIDJZKBVIEO-UHFFFAOYSA-N	97065	3-(((R)-3-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)- 1,2,3,4,4a,5- hexahydrobenzo[b]pyrazino[1,2- d][1,4]oxazin-8-yl)amino)piperidine-2,6- dione::US20260000676, Compound A94	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97065	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97065&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2372982	164038309							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130716	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@H]2CN(CC3CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-29-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-16-14-48(15-17-51)23-30(24-48)25-50-18-19-52-35(27-50)28-58-43-22-38-33(20-41(43)52)26-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	JGUADLWFBMOXGP-UHFFFAOYSA-N	97066	(R)-3-((R)-3-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A95	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97066	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97066&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			714273	164038310							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130717	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-29-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-16-14-48(15-17-51)23-30(24-48)25-50-18-19-52-35(27-50)28-58-43-22-38-33(20-41(43)52)26-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	JGUADLWFBMOXGP-UHFFFAOYSA-N	97067	(R)-3-((S)-3-((7-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A96	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97067	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97067&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			730925	164038311							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130718	COc1nc(C(=O)NC2CCC(=O)NC2=O)ccc1N1CCN(CC2CC3(CCN(c4ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc4)CC3)C2)CC1	InChI=1S/C46H52N6O6/c1-57-45-39(15-13-38(48-45)43(55)47-37-14-16-41(54)49-44(37)56)52-23-21-50(22-24-52)28-30-26-46(27-30)17-19-51(20-18-46)33-9-7-32(8-10-33)42-35-12-11-34(53)25-40(35)58-29-36(42)31-5-3-2-4-6-31/h2-13,15,25,30,36-37,42,53H,14,16-24,26-29H2,1H3,(H,47,55)(H,49,54,56)	LOWCQNDEZXEJJP-UHFFFAOYSA-N	97068	N-(2,6-dioxopiperidin-3-yl)-5-(4-((7-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-7-azaspiro[3.5]nonan-2- yl)methyl)piperazin-1-yl)-6- methoxypicolinamide::US20260000676, Compound A97	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97068	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97068&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1155337	164038312							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130719	O=C1CCC(N2Cc3cc(N4CCN(CC5CC6(CCN(c7ccc([C@H]8c9ccc(O)cc9OC[C@H]8c8ccccc8)cn7)CC6)C5)CC4)ccc3C2=O)C(=O)N1	InChI=1S/C46H50N6O5/c53-35-8-10-37-40(23-35)57-29-38(31-4-2-1-3-5-31)43(37)32-6-12-41(47-26-32)51-16-14-46(15-17-51)24-30(25-46)27-49-18-20-50(21-19-49)34-7-9-36-33(22-34)28-52(45(36)56)39-11-13-42(54)48-44(39)55/h1-10,12,22-23,26,30,38-39,43,53H,11,13-21,24-25,27-29H2,(H,48,54,55)	MOXUHRVGVLTQQM-UHFFFAOYSA-N	97069	(R)-3-(5-(4-((7-(5-((3R,4S)-7-hydroxy-3- 3-phenylchroman-4-yl)pyridin-2-yl)-7- azaspiro[3.5]nonan-2- yl)methyl)piperazin-1-yl)-1- oxoisoindolin-2-yl)piperidine-2,6-dione::US20260000676, Compound A98	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97069	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97069&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			842058	164038313							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130720	O=C1CCC(N2Cc3cc4c(cc3C2=O)OCC42CCN(CC3CCC4(CC3)CN(c3ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc3)C4)CC2)C(=O)N1	InChI=1S/C49H52N4O6/c54-36-10-11-37-42(23-36)58-27-39(32-4-2-1-3-5-32)45(37)33-6-8-35(9-7-33)52-28-48(29-52)16-14-31(15-17-48)25-51-20-18-49(19-21-51)30-59-43-24-38-34(22-40(43)49)26-53(47(38)57)41-12-13-44(55)50-46(41)56/h1-11,22-24,31,39,41,45,54H,12-21,25-30H2,(H,50,55,56)	CMWAKGDTWQNPJP-UHFFFAOYSA-N	97070	3-(1'-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-7-oxo- 5,7-dihydro-2H,6H-spiro[furo[2,3- f]isoindole-3,4'-piperidin]-6-yl)piperidine- 2,6-dione::US20260000676, Compound A99	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97070	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97070&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1254286	164038314							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130721	O=C1CCC(NC(=O)c2ccc(N3CCN(CC4CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5F)CC4)CC3)cn2)C(=O)N1	InChI=1S/C42H45FN6O5/c43-34-22-29(40-32-9-8-31(50)23-38(32)54-26-33(40)28-4-2-1-3-5-28)6-12-37(34)49-16-14-27(15-17-49)25-47-18-20-48(21-19-47)30-7-10-35(44-24-30)41(52)45-36-11-13-39(51)46-42(36)53/h1-10,12,22-24,27,33,36,40,50H,11,13-21,25-26H2,(H,45,52)(H,46,51,53)	JJXHYLDMEUEYBJ-UHFFFAOYSA-N	97071	N-(2,6-dioxopiperidin-3-yl)-5-(4-((1-(2- fluoro-4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)piperazin-1-yl)picolinamide::US20260000676, Compound A100	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97071	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97071&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1966784	164038315							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130722	O=C1CCC(NC(=O)c2ccc(C3CCN(CC4CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5F)CC4)CC3)cn2)C(=O)N1	InChI=1S/C43H46FN5O5/c44-35-22-30(41-33-9-8-32(50)23-39(33)54-26-34(41)29-4-2-1-3-5-29)7-12-38(35)49-20-14-27(15-21-49)25-48-18-16-28(17-19-48)31-6-10-36(45-24-31)42(52)46-37-11-13-40(51)47-43(37)53/h1-10,12,22-24,27-28,34,37,41,50H,11,13-21,25-26H2,(H,46,52)(H,47,51,53)	YTEFFMGWAFHWCN-UHFFFAOYSA-N	97072	N-(2,6-dioxopiperidin-3-yl)-5-(1-((1-(2- fluoro-4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)piperidin-4-yl)picolinamide::US20260000676, Compound A101	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97072	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97072&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2464572	164038316							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130723	COc1nc(C(=O)NC2CCC(=O)NC2=O)ccc1N1CCN(CC2CCN(c3ccc([C@H]4c5ccc(O)cc5OC[C@H]4c4ccccc4)cc3F)CC2)CC1	InChI=1S/C43H47FN6O6/c1-55-43-37(13-10-35(46-43)41(53)45-34-11-14-39(52)47-42(34)54)50-21-19-48(20-22-50)25-27-15-17-49(18-16-27)36-12-7-29(23-33(36)44)40-31-9-8-30(51)24-38(31)56-26-32(40)28-5-3-2-4-6-28/h2-10,12-13,23-24,27,32,34,40,51H,11,14-22,25-26H2,1H3,(H,45,53)(H,47,52,54)	PFEFGDOFONBZBV-UHFFFAOYSA-N	97073	N-(2,6-dioxopiperidin-3-yl)-5-(4-((1-(2- fluoro-4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)piperazin-1-yl)-6- methoxypicolinamide::US20260000676, Compound A102	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97073	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97073&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2405889	164038317							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130724	O=C1CCC(NC(=O)c2ccc3c(n2)OC[C@H]2CN(CC4CCN(c5ccc([C@H]6c7ccc(O)cc7OCC6c6ccccc6)cc5F)CC4)CCN32)C(=O)N1	InChI=1S/C43H45FN6O6/c44-33-20-28(40-31-8-7-30(51)21-38(31)55-25-32(40)27-4-2-1-3-5-27)6-11-36(33)49-16-14-26(15-17-49)22-48-18-19-50-29(23-48)24-56-43-37(50)12-9-35(46-43)41(53)45-34-10-13-39(52)47-42(34)54/h1-9,11-12,20-21,26,29,32,34,40,51H,10,13-19,22-25H2,(H,45,53)(H,47,52,54)	JBUKPSGLNNCCMM-UHFFFAOYSA-N	97074	(4aR)-N-(2,6-dioxopiperidin-3-yl)-3-((1- (2-fluoro-4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)-1,2,3,4,4a,5- hexahydropyrazino[1,2-d]pyrido[2,3- b][1,4]oxazine-8-carboxamide::US20260000676, Compound A103	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97074	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97074&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			976991	164038318							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130725	O=C1CCC(NC(=O)c2ccc3c(n2)OC[C@H]2CN(CC4CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5F)CC4)CCN32)C(=O)N1	InChI=1S/C43H45FN6O6/c44-33-20-28(40-31-8-7-30(51)21-38(31)55-25-32(40)27-4-2-1-3-5-27)6-11-36(33)49-16-14-26(15-17-49)22-48-18-19-50-29(23-48)24-56-43-37(50)12-9-35(46-43)41(53)45-34-10-13-39(52)47-42(34)54/h1-9,11-12,20-21,26,29,32,34,40,51H,10,13-19,22-25H2,(H,45,53)(H,47,52,54)	JBUKPSGLNNCCMM-UHFFFAOYSA-N	97075	(4aR)-N-(2,6-dioxopiperidin-3-yl)-3-((1- (2-fluoro-4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)-1,2,3,4,4a,5- hexahydropyrazino[1,2-d]pyrido[2,3- b][1,4]oxazine-8-carboxamide::US20260000676, Compound A104	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97075	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97075&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			91899623	164038319							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130726	COc1cc(N2CCC(CN3CCN4c5ccc6c(c5OC[C@H]4C3)CN(C3CCC(=O)NC3=O)C6=O)CC2)c(F)cc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C46H48FN5O7/c1-57-40-21-39(36(47)20-33(40)43-32-8-7-30(53)19-41(32)58-26-35(43)28-5-3-2-4-6-28)50-15-13-27(14-16-50)22-49-17-18-51-29(23-49)25-59-44-34-24-52(38-11-12-42(54)48-45(38)55)46(56)31(34)9-10-37(44)51/h2-10,19-21,27,29,35,38,43,53H,11-18,22-26H2,1H3,(H,48,54,55)	ABYHVQGAUUOKSI-UHFFFAOYSA-N	97076	(R)-3-((S)-7-((1-(2-fluoro-4-((3R,4R)-7- hydroxy-3-phenylchroman-4-yl)-5- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,7-dione::US20260000676, Compound A105	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97076	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97076&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			6077070	164038320							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130727	COc1cc(N2CCC(CN3CCN4c5ccc6c(c5OC[C@@H]4C3)CN([C@@H]3CCC(=O)NC3=O)C6=O)CC2)c(F)cc1[C@@H]1c2ccc(O)cc2OC[C@@H]1c1ccccc1	InChI=1S/C46H48FN5O7/c1-57-40-21-39(36(47)20-33(40)43-32-8-7-30(53)19-41(32)58-26-35(43)28-5-3-2-4-6-28)50-15-13-27(14-16-50)22-49-17-18-51-29(23-49)25-59-44-34-24-52(38-11-12-42(54)48-45(38)55)46(56)31(34)9-10-37(44)51/h2-10,19-21,27,29,35,38,43,53H,11-18,22-26H2,1H3,(H,48,54,55)	ABYHVQGAUUOKSI-UHFFFAOYSA-N	97078	(R)-3-((S)-7-((1-(2-fluoro-4-((3S,4S)-7- hydroxy-3-phenylchroman-4-yl)-5- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A106	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97078	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97078&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			20231	164038322							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130728	O=C1CCN(c2ccc(N3CCC4(CC3)CC(CN3CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC3)C4)cc2)C(=O)N1	InChI=1S/C44H49N5O4/c50-37-14-15-38-40(26-37)53-30-39(32-4-2-1-3-5-32)42(38)33-6-8-34(9-7-33)48-24-22-46(23-25-48)29-31-27-44(28-31)17-20-47(21-18-44)35-10-12-36(13-11-35)49-19-16-41(51)45-43(49)52/h1-15,26,31,39,42,50H,16-25,27-30H2,(H,45,51,52)	RXUDRFOWCCWJCN-UHFFFAOYSA-N	97079	1-(4-(2-((4-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperazin- 1-yl)methyl)-7-azaspiro[3.5]nonan-7- yl)phenyl)dihydropyrimidine- 2,4(1H,3H)-dione::US20260000676, Compound A107	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97079	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97079&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			3695590	164038323							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130729	COc1nc(C(=O)NC2CCC(=O)NC2=O)ccc1N1CCN(CC2CCC3(CC2)CN(c2ccc([C@@H]4c5ccc(O)cc5OC[C@@H]4c4ccccc4)cc2)C3)CC1	InChI=1S/C46H52N6O6/c1-57-45-39(15-13-38(48-45)43(55)47-37-14-16-41(54)49-44(37)56)51-23-21-50(22-24-51)26-30-17-19-46(20-18-30)28-52(29-46)33-9-7-32(8-10-33)42-35-12-11-34(53)25-40(35)58-27-36(42)31-5-3-2-4-6-31/h2-13,15,25,30,36-37,42,53H,14,16-24,26-29H2,1H3,(H,47,55)(H,49,54,56)	KSMVHWVTYYBUSG-UHFFFAOYSA-N	97080	N-(2,6-dioxopiperidin-3-yl)-5-(4-((2-(4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-2-azaspiro[3.5]nonan-7- yl)methyl)piperazin-1-yl)-6- methoxypicolinamide::US20260000676, Compound A108	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97080	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97080&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2874826	164038324							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130730	COc1cc(N2CCC(CN3CCN(c4ccc(C(=O)NC5CCC(=O)NC5=O)nc4)CC3)CC2)c(F)cc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C43H47FN6O6/c1-55-38-23-37(34(44)22-32(38)41-31-9-8-30(51)21-39(31)56-26-33(41)28-5-3-2-4-6-28)50-15-13-27(14-16-50)25-48-17-19-49(20-18-48)29-7-10-35(45-24-29)42(53)46-36-11-12-40(52)47-43(36)54/h2-10,21-24,27,33,36,41,51H,11-20,25-26H2,1H3,(H,46,53)(H,47,52,54)	GDFNZUUTQPQEIV-UHFFFAOYSA-N	97081	N-(2,6-dioxopiperidin-3-yl)-5-(4-((1-(2- fluoro-4-((3R,4R)-7-hydroxy-3- phenylchroman-4-yl)-5- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)picolinamide::US20260000676, Compound A109	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97081	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97081&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			3111187	164038325							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130731	COc1cc(N2CCC(CN3CCN(c4ccc(C(=O)NC5CCC(=O)NC5=O)nc4)CC3)CC2)c(F)cc1[C@H]1c2ccc(O)cc2CC[C@H]1c1ccccc1	InChI=1S/C44H49FN6O5/c1-56-40-25-39(36(45)24-35(40)42-33(29-5-3-2-4-6-29)10-7-30-23-32(52)9-11-34(30)42)51-17-15-28(16-18-51)27-49-19-21-50(22-20-49)31-8-12-37(46-26-31)43(54)47-38-13-14-41(53)48-44(38)55/h2-6,8-9,11-12,23-26,28,33,38,42,52H,7,10,13-22,27H2,1H3,(H,47,54)(H,48,53,55)	YMILKCLHVQTTEF-UHFFFAOYSA-N	97082	N-(2,6-dioxopiperidin-3-yl)-5-(4-((1-(2- fluoro-4-((3R,4R)-7-hydroxy-3- phenylchroman-4-yl)-5- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)picolinamide::US20260000676, Compound A110	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97082	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97082&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1952659	164038326							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130732	O=C1CC[C@@H](NC(=O)c2ccc(N3CCC(CN4CC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C4)CC3)cn2)C(=O)N1	InChI=1S/C45H50N6O5/c52-35-11-12-36-40(24-35)56-27-37(31-4-2-1-3-5-31)42(36)32-6-8-33(9-7-32)51-22-18-45(19-23-51)28-49(29-45)26-30-16-20-50(21-17-30)34-10-13-38(46-25-34)43(54)47-39-14-15-41(53)48-44(39)55/h1-13,24-25,30,37,39,42,52H,14-23,26-29H2,(H,47,54)(H,48,53,55)	XVVSQCDQVGMBIT-UHFFFAOYSA-N	97083	N-((R)-2,6-dioxopiperidin-3-yl)-5-(4-((7- (4-((3R,4S)-7-hydroxy-3-phenylchroman- 4-yl)phenyl)-2,7-diazaspiro[3.5]nonan-2- yl)methyl)piperidin-1-yl)picolinamide::US20260000676, Compound A111	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97083	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97083&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1046754	164038327							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130733	O=C1CCC(N2Cc3c(ccc4c3OCC43CCN(CC4CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CC3)C2=O)C(=O)N1	InChI=1S/C49H52N4O6/c54-35-10-11-37-42(24-35)58-29-39(32-4-2-1-3-5-32)44(37)33-6-8-34(9-7-33)52-22-16-48(17-23-52)25-31(26-48)27-51-20-18-49(19-21-51)30-59-45-38-28-53(41-14-15-43(55)50-46(41)56)47(57)36(38)12-13-40(45)49/h1-13,24,31,39,41,44,54H,14-23,25-30H2,(H,50,55,56)	BUNBYWKAYABLSW-UHFFFAOYSA-N	97084	3-(1'-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-6-oxo- 6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A113	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97084	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97084&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			5517556	164038328							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130734	O=C1CCC(N2Cc3c(ccc4c3OCC43CCN(CC4CCC5(CC4)CN(c4ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc4)C5)CC3)C2=O)C(=O)N1	InChI=1S/C49H52N4O6/c54-35-10-11-37-42(24-35)58-27-39(32-4-2-1-3-5-32)44(37)33-6-8-34(9-7-33)52-28-48(29-52)18-16-31(17-19-48)25-51-22-20-49(21-23-51)30-59-45-38-26-53(41-14-15-43(55)50-46(41)56)47(57)36(38)12-13-40(45)49/h1-13,24,31,39,41,44,54H,14-23,25-30H2,(H,50,55,56)	BPZMDXPICADHQA-UHFFFAOYSA-N	97085	3-(1'-((2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-6-oxo- 6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A114	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97085	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97085&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			5613808	164038329							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130735	O=C1CC[C@H](N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCC6(CC5)CN(c5ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc5)C6)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O6/c54-35-10-11-37-42(22-35)58-27-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-28-48(29-51)18-16-30(17-19-48)23-50-20-21-52-34(24-50)26-59-45-38-25-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	VMPKZWYOZWRHDR-UHFFFAOYSA-N	97086	(S)-3-((R)-7-((2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A115	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97086	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97086&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			6906133	164038330							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130736	COc1cc(C(=O)NC2CCC(=O)NC2=O)ncc1N1CCN(CC2CC3(CCN(c4ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc4)CC3)C2)CC1	InChI=1S/C46H52N6O6/c1-57-41-24-38(45(56)48-37-13-14-42(54)49-44(37)55)47-27-39(41)52-21-19-50(20-22-52)28-30-25-46(26-30)15-17-51(18-16-46)33-9-7-32(8-10-33)43-35-12-11-34(53)23-40(35)58-29-36(43)31-5-3-2-4-6-31/h2-12,23-24,27,30,36-37,43,53H,13-22,25-26,28-29H2,1H3,(H,48,56)(H,49,54,55)	NEHPFQCGFCHTJQ-UHFFFAOYSA-N	97087	N-(2,6-dioxopiperidin-3-yl)-5-(4-((7-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-7-azaspiro[3.5]nonan-2- yl)methyl)piperazin-1-yl)-4- methoxypicolinamidc::US20260000676, Compound A116	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97087	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97087&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			4412278	164038331							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130737	COc1cc(C(=O)NC2CCC(=O)NC2=O)ncc1N1CCN(CC2CCC3(CC2)CN(c2ccc([C@H]4c5ccc(O)cc5OC[C@H]4c4ccccc4)cc2)C3)CC1	InChI=1S/C46H52N6O6/c1-57-41-24-38(45(56)48-37-13-14-42(54)49-44(37)55)47-25-39(41)51-21-19-50(20-22-51)26-30-15-17-46(18-16-30)28-52(29-46)33-9-7-32(8-10-33)43-35-12-11-34(53)23-40(35)58-27-36(43)31-5-3-2-4-6-31/h2-12,23-25,30,36-37,43,53H,13-22,26-29H2,1H3,(H,48,56)(H,49,54,55)	VTECJCSWJYJOBF-UHFFFAOYSA-N	97088	rac-N-(2,6-dioxopiperidin-3-yl)-5-(4-((2- (4-((3R,4S)-7-hydroxy-3-phenylchroman- 4-yl)phenyl)-2-azaspiro[3.5]nonan-7- yl)methyl)piperazin-1-yl)-4- methoxypicolinamide::US20260000676, Compound A117	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97088	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97088&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			4544702	164038332							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130738	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@H]2CN(CC3CCC5(CC3)CN(c3ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc3)C5)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-27-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-28-48(29-51)16-14-30(15-17-48)23-50-18-19-52-35(25-50)26-58-43-22-38-33(20-41(43)52)24-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	IKGGCVYEWPPTHT-UHFFFAOYSA-N	97089	(R)-3-((R)-3-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A118	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97089	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97089&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1321677	164038333							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130739	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@H]2CN(CC3CCC5(CC3)CN(c3ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc3)C5)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-27-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-28-48(29-51)16-14-30(15-17-48)23-50-18-19-52-35(25-50)26-58-43-22-38-33(20-41(43)52)24-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	IKGGCVYEWPPTHT-UHFFFAOYSA-N	97090	(R)-3-((R)-3-((2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A119	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97090	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97090&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2974020	164038334							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130740	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCC5(CC3)CN(c3ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc3)C5)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-27-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-28-48(29-51)16-14-30(15-17-48)23-50-18-19-52-35(25-50)26-58-43-22-38-33(20-41(43)52)24-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	IKGGCVYEWPPTHT-UHFFFAOYSA-N	97091	(R)-3-((S)-3-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A120	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97091	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97091&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1211814	164038335							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130741	COc1cc(N2CCC(CN3CCN4c5ccc6c(c5OC[C@@H]4C3)CN([C@@H]3CCC(=O)NC3=O)C6=O)CC2)ccc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C46H49N5O7/c1-56-40-21-30(7-9-34(40)43-35-10-8-32(52)22-41(35)57-27-37(43)29-5-3-2-4-6-29)49-17-15-28(16-18-49)23-48-19-20-50-31(24-48)26-58-44-36-25-51(39-13-14-42(53)47-45(39)54)46(55)33(36)11-12-38(44)50/h2-12,21-22,28,31,37,39,43,52H,13-20,23-27H2,1H3,(H,47,53,54)	KFOQSSLNXOAYPF-UHFFFAOYSA-N	97092	(R)-3-((S)-7-((1-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A121	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97092	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97092&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			787494	164038336							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130742	COc1cc(N2CCC(CN3CCN4c5cc6c(cc5OC[C@H]4C3)C(=O)N([C@@H]3CCC(=O)NC3=O)C6)CC2)ccc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C46H49N5O7/c1-56-40-20-31(7-9-34(40)44-35-10-8-33(52)21-41(35)58-27-37(44)29-5-3-2-4-6-29)49-15-13-28(14-16-49)23-48-17-18-50-32(25-48)26-57-42-22-36-30(19-39(42)50)24-51(46(36)55)38-11-12-43(53)47-45(38)54/h2-10,19-22,28,32,37-38,44,52H,11-18,23-27H2,1H3,(H,47,53,54)	FAZUJCHEBBDOGY-UHFFFAOYSA-N	97093	(R)-3-((R)-3-((1-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A122	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97093	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97093&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			5604202	164038337							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130743	O=C1CCC(N2Cc3cc4c(cc3C2=O)OCC42CCN(CC3CC4(CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cn5)CC4)C3)CC2)C(=O)N1	InChI=1S/C48H51N5O6/c54-34-7-8-35-40(21-34)58-28-37(31-4-2-1-3-5-31)44(35)32-6-10-42(49-25-32)52-18-12-47(13-19-52)23-30(24-47)26-51-16-14-48(15-17-51)29-59-41-22-36-33(20-38(41)48)27-53(46(36)57)39-9-11-43(55)50-45(39)56/h1-8,10,20-22,25,30,37,39,44,54H,9,11-19,23-24,26-29H2,(H,50,55,56)	HNPQTADTBSZCMP-UHFFFAOYSA-N	97094	3-(1'-((7-(5-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)pyridin-2-yl)-7- azaspiro[3.5]nonan-2-yl)methyl)-7-oxo- 5,7-dihydro-2H,6H-spiro[furo[2,3- f]isoindole-3,4'-piperidin]-6-yl)piperidine- 2,6-dione::US20260000676, Compound A123	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97094	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97094&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2204911	164038338							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130744	COc1cc(N2CCC(CN3CCN(c4ccc(C(=O)NC5CCC(=O)NC5=O)nc4)CC3)CC2)ccc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C43H48N6O6/c1-54-38-23-30(7-10-33(38)41-34-11-9-32(50)24-39(34)55-27-35(41)29-5-3-2-4-6-29)48-17-15-28(16-18-48)26-47-19-21-49(22-20-47)31-8-12-36(44-25-31)42(52)45-37-13-14-40(51)46-43(37)53/h2-12,23-25,28,35,37,41,50H,13-22,26-27H2,1H3,(H,45,52)(H,46,51,53)	XNSQIMMUGFTIRJ-UHFFFAOYSA-N	97095	N-(2,6-dioxopiperidin-3-yl)-5-(4-((1-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)-3-methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)picolinamide::US20260000676, Compound A124	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97095	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97095&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			934786	164038339							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130745	COc1cc(N2CCC3(CC2)CC(CN2CCN4c5ccc6c(c5OC[C@@H]4C2)CN([C@@H]2CCC(=O)NC2=O)C6=O)C3)c(F)cc1[C@@H]1c2ccc(O)cc2OC[C@@H]1c1ccccc1	InChI=1S/C49H52FN5O7/c1-60-42-21-41(38(50)20-35(42)45-34-8-7-32(56)19-43(34)61-28-37(45)30-5-3-2-4-6-30)53-15-13-49(14-16-53)22-29(23-49)24-52-17-18-54-31(25-52)27-62-46-36-26-55(40-11-12-44(57)51-47(40)58)48(59)33(36)9-10-39(46)54/h2-10,19-21,29,31,37,40,45,56H,11-18,22-28H2,1H3,(H,51,57,58)	RRPOCDMJIPJJHE-UHFFFAOYSA-N	97096	(R)-3-((S)-7-((7-(2-fluoro-4-((3S,4S)-7- hydroxy-3-phenylchroman-4-yl)-5- methoxyphenyl)-7-azaspiro[3.5]nonan-2- yl)methyl)-1-oxo-1,3,5,5a,6,7,8,9- octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A125	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97096	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97096&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2240759	164038340							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130746	COc1cc(N2CCC3(CC2)CC(CN2CCN4c5ccc6c(c5OC[C@@H]4C2)CN([C@@H]2CCC(=O)NC2=O)C6=O)C3)c(F)cc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C49H52FN5O7/c1-60-42-21-41(38(50)20-35(42)45-34-8-7-32(56)19-43(34)61-28-37(45)30-5-3-2-4-6-30)53-15-13-49(14-16-53)22-29(23-49)24-52-17-18-54-31(25-52)27-62-46-36-26-55(40-11-12-44(57)51-47(40)58)48(59)33(36)9-10-39(46)54/h2-10,19-21,29,31,37,40,45,56H,11-18,22-28H2,1H3,(H,51,57,58)	RRPOCDMJIPJJHE-UHFFFAOYSA-N	97097	(R)-3-((S)-7-((7-(2-fluoro-4-((3R,4R)-7- hydroxy-3-phenylchroman-4-yl)-5- methoxyphenyl)-7-azaspiro[3.5]nonan-2- yl)methyl)-1-oxo-1,3,5,5a,6,7,8,9- octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A126	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97097	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97097&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			951643	164038341							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130747	COc1cc(N2CCC(CN3CCN(c4cnc(C(=O)NC5CCC(=O)NC5=O)cc4OC)CC3)CC2)ccc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C44H50N6O7/c1-55-38-22-30(8-10-32(38)42-33-11-9-31(51)23-39(33)57-27-34(42)29-6-4-3-5-7-29)49-16-14-28(15-17-49)26-48-18-20-50(21-19-48)37-25-45-36(24-40(37)56-2)44(54)46-35-12-13-41(52)47-43(35)53/h3-11,22-25,28,34-35,42,51H,12-21,26-27H2,1-2H3,(H,46,54)(H,47,52,53)	OMHCGTCMFJLIGD-UHFFFAOYSA-N	97098	N-(2,6-dioxopiperidin-3-yl)-5-(4-((1-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)-3-methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)-4- methoxypicolinamide::US20260000676, Compound A127	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97098	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97098&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2238406	164038342							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130748	O=C1CCC(NC(=O)c2ccc(N3CCC(CN4CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC4)CC3)cn2)C(=O)N1	InChI=1S/C42H46N6O5/c49-33-11-12-34-38(24-33)53-27-35(29-4-2-1-3-5-29)40(34)30-6-8-31(9-7-30)48-22-20-46(21-23-48)26-28-16-18-47(19-17-28)32-10-13-36(43-25-32)41(51)44-37-14-15-39(50)45-42(37)52/h1-13,24-25,28,35,37,40,49H,14-23,26-27H2,(H,44,51)(H,45,50,52)	SAHKNDRITROFCC-UHFFFAOYSA-N	97099	N-(2,6-dioxopiperidin-3-yl)-5-(4-((4-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)piperazin-1-yl)methyl)piperidin- 1-yl)picolinamide::US20260000676, Compound A128	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97099	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97099&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1799112	164038343							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130749	O=C1CCC(NC(=O)c2ccc(N3CCC(CN4CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC4)CC3)cn2)C(=O)N1	InChI=1S/C42H46N6O5/c49-33-11-12-34-38(24-33)53-27-35(29-4-2-1-3-5-29)40(34)30-6-8-31(9-7-30)48-22-20-46(21-23-48)26-28-16-18-47(19-17-28)32-10-13-36(43-25-32)41(51)44-37-14-15-39(50)45-42(37)52/h1-13,24-25,28,35,37,40,49H,14-23,26-27H2,(H,44,51)(H,45,50,52)	SAHKNDRITROFCC-UHFFFAOYSA-N	97100	N-(2,6-dioxopiperidin-3-yl)-5-(4-((4-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)piperazin-1-yl)methyl)piperidin- 1-yl)picolinamide::US20260000676, Compound A129	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97100	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97100&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2931999	164038344							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130750	COc1cc(N2CCC3(CC2)CC(CN2CCC4(CC2)COc2c4ccc4c2CN(C2CCC(=O)NC2=O)C4=O)C3)c(F)cc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C50H53FN4O7/c1-60-42-23-41(39(51)22-35(42)45-34-8-7-32(56)21-43(34)61-28-37(45)31-5-3-2-4-6-31)54-19-13-49(14-20-54)24-30(25-49)26-53-17-15-50(16-18-53)29-62-46-36-27-55(40-11-12-44(57)52-47(40)58)48(59)33(36)9-10-38(46)50/h2-10,21-23,30,37,40,45,56H,11-20,24-29H2,1H3,(H,52,57,58)	STVVTUOREOYWID-UHFFFAOYSA-N	97101	3-(1'-((7-(2-fluoro-4-((3R,4R)-7-hydroxy- 3-phenylchroman-4-yl)-5- methoxyphenyl)-7-azaspiro[3.5]nonan-2- yl)methyl)-6-oxo-6,8-dihydro-2H,7H- spiro[furo[2,3-e]isoindole-3,4'-piperidin]- 7-yl)piperidine-2,6-dione::US20260000676, Compound A130	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97101	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97101&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1126136	164038345							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130751	COc1cc(N2CCC3(CC2)CC(CN2CCC4(CC2)COc2c4ccc4c2CN(C2CCC(=O)NC2=O)C4=O)C3)c(F)cc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C50H53FN4O7/c1-60-42-23-41(39(51)22-35(42)45-34-8-7-32(56)21-43(34)61-28-37(45)31-5-3-2-4-6-31)54-19-13-49(14-20-54)24-30(25-49)26-53-17-15-50(16-18-53)29-62-46-36-27-55(40-11-12-44(57)52-47(40)58)48(59)33(36)9-10-38(46)50/h2-10,21-23,30,37,40,45,56H,11-20,24-29H2,1H3,(H,52,57,58)	STVVTUOREOYWID-UHFFFAOYSA-N	97102	3-(1'-((7-(2-fluoro-4-((3R,4R)-7-hydroxy- 3-phenylchroman-4-yl)-5- methoxyphenyl)-7-azaspiro[3.5]nonan-2- yl)methyl)-6-oxo-6,8-dihydro-2H,7H- spiro[furo[2,3-e]isoindole-3,4'-piperidin]- 7-yl)piperidine-2,6-dione::US20260000676, Compound A131	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97102	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97102&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			548479	164038346					C04080		2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130752	O=C1CC[C@@H](N2Cc3c(ccc4c3OC[C@@H]3CN(C[C@@H]5COC6(CCN(c7ccc([C@H]8c9ccc(O)cc9OC[C@H]8c8ccccc8)cc7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O7/c54-35-10-11-37-42(22-35)58-29-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-18-16-48(17-19-51)23-30(27-60-48)24-50-20-21-52-34(25-50)28-59-45-38-26-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	NGKUCSTXXZJYFQ-UHFFFAOYSA-N	97103	(R)-3-((S)-7-(((R)-8-(4-((3R,4S)-7- hydroxy-3-phenylchroman-4-yl)phenyl)-1- oxa-8-azaspiro[4.5]dccan-3-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A132	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97103	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97103&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			4157793	164038347							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130753	O=C1CC[C@@H](N2Cc3c(ccc4c3OC[C@@H]3CN(C[C@H]5COC6(CCN(c7ccc([C@H]8c9ccc(O)cc9OC[C@H]8c8ccccc8)cc7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O7/c54-35-10-11-37-42(22-35)58-29-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-18-16-48(17-19-51)23-30(27-60-48)24-50-20-21-52-34(25-50)28-59-45-38-26-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	NGKUCSTXXZJYFQ-UHFFFAOYSA-N	97104	(R)-3-((S)-7-(((S)-8-(4-((3R,4S)-7- hydroxy-3-phenylchroman-4-yl)phenyl)-1- oxa-8-azaspiro[4.5]decan-3-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A133	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97104	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97104&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			3104736	164038348							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130754	COc1cc(N2CCC(CN3CCN4c5ccc(C(=O)NC6CCC(=O)NC6=O)nc5OC[C@H]4C3)CC2)ccc1[C@@H]1c2ccc(O)cc2OC[C@@H]1c1ccccc1	InChI=1S/C44H48N6O7/c1-55-38-21-29(7-9-32(38)41-33-10-8-31(51)22-39(33)56-26-34(41)28-5-3-2-4-6-28)49-17-15-27(16-18-49)23-48-19-20-50-30(24-48)25-57-44-37(50)13-11-36(46-44)42(53)45-35-12-14-40(52)47-43(35)54/h2-11,13,21-22,27,30,34-35,41,51H,12,14-20,23-26H2,1H3,(H,45,53)(H,47,52,54)	SVMHYDKBQVEMPG-UHFFFAOYSA-N	97105	(4aR)-N-(2,6-dioxopiperidin-3-yl)-3-((1- (4-((3S,4R)-7-hydroxy-3-phenylchroman- 4-yl)-3-methoxyphenyl)piperidin-4- yl)methyl)-1,2,3,4,4a,5- hexahydropyrazino[1,2-d]pyrido[2,3- b][1,4]oxazine-8-carboxamide::US20260000676, Compound A134	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97105	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97105&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			16193721	164038349							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130755	COc1cc(N2CCC(CN3CCC4(CC3)COc3c4ccc4c3CN(C3CCC(=O)NC3=O)C4=O)CC2)ccc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C47H50N4O7/c1-56-40-23-31(7-9-34(40)43-35-10-8-32(52)24-41(35)57-27-37(43)30-5-3-2-4-6-30)50-19-15-29(16-20-50)25-49-21-17-47(18-22-49)28-58-44-36-26-51(39-13-14-42(53)48-45(39)54)46(55)33(36)11-12-38(44)47/h2-12,23-24,29,37,39,43,52H,13-22,25-28H2,1H3,(H,48,53,54)	HWCRAIQSYXFHSR-UHFFFAOYSA-N	97106	3-(1'-((1-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-6- oxo-6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A135	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97106	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97106&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			54681625	164038350							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130756	COc1cc(N2CCC(CN3CCC4(CC3)COc3cc5c(cc34)CN(C3CCC(=O)NC3=O)C5=O)CC2)ccc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C47H50N4O7/c1-56-40-22-32(7-9-34(40)44-35-10-8-33(52)23-41(35)57-27-37(44)30-5-3-2-4-6-30)50-17-13-29(14-18-50)25-49-19-15-47(16-20-49)28-58-42-24-36-31(21-38(42)47)26-51(46(36)55)39-11-12-43(53)48-45(39)54/h2-10,21-24,29,37,39,44,52H,11-20,25-28H2,1H3,(H,48,53,54)	BLLHNCYYRIJFSD-UHFFFAOYSA-N	97107	3-(1'-((1-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-7- oxo-5,7-dihydro-2H,6H-spiro[furo[2,3- f]isoindole-3,4'-piperidin]-6-yl)piperidine- 2,6-dione::US20260000676, Compound A136	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97107	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97107&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			3548924	164038351							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130757	O=C1CCC(N2Cc3ccc4c(c3C2=O)OCC42CCN(CC3COC4(CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC4)C3)CC2)C(=O)N1	InChI=1S/C49H52N4O7/c54-36-11-12-37-41(24-36)58-29-38(32-4-2-1-3-5-32)43(37)33-6-9-35(10-7-33)52-22-18-49(19-23-52)25-31(28-60-49)26-51-20-16-48(17-21-51)30-59-45-39(48)13-8-34-27-53(47(57)44(34)45)40-14-15-42(55)50-46(40)56/h1-13,24,31,38,40,43,54H,14-23,25-30H2,(H,50,55,56)	QCJKIAQNQAZEPK-UHFFFAOYSA-N	97108	3-(1'-((8-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-1-oxa-8- azaspiro[4.5]decan-3-yl)methyl)-6-oxo- 6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A137	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97108	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97108&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2100093	164038352							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130758	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@H]2CN(CC3COC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H51N5O7/c54-36-10-11-37-42(21-36)59-29-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-16-14-48(15-17-51)23-30(27-60-48)24-50-18-19-52-35(26-50)28-58-43-22-38-33(20-41(43)52)25-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	NEVLLZDNWSSISS-UHFFFAOYSA-N	97109	(3R)-3-((4aR)-3-((8-(4-((3R,4S)-7- hydroxy-3-phenylchroman-4-yl)phenyl)-1- oxa-8-azaspiro[4.5]decan-3-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A138	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97109	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97109&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2508533	164038353							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130759	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@H]2CN(CC3COC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H51N5O7/c54-36-10-11-37-42(21-36)59-29-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-16-14-48(15-17-51)23-30(27-60-48)24-50-18-19-52-35(26-50)28-58-43-22-38-33(20-41(43)52)25-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	NEVLLZDNWSSISS-UHFFFAOYSA-N	97110	(3R)-3-((4aR)-3-((8-(4-((3S,4R)-7- hydroxy-3-phenylchroman-4-yl)phenyl)-1- oxa-8-azaspiro[4.5]decan-3-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A139	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97110	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97110&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2356907	164038354							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130760	O=C1CC[C@@H](Nc2ccc(C3CCN(CC4CCC5(CC4)CN(c4ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc4)C5)CC3)cc2)C(=O)N1	InChI=1S/C46H52N4O4/c51-38-14-15-39-42(26-38)54-28-40(34-4-2-1-3-5-34)44(39)35-8-12-37(13-9-35)50-29-46(30-50)22-18-31(19-23-46)27-49-24-20-33(21-25-49)32-6-10-36(11-7-32)47-41-16-17-43(52)48-45(41)53/h1-15,26,31,33,40-41,44,47,51H,16-25,27-30H2,(H,48,52,53)	FXZDRKDLUPUSJF-UHFFFAOYSA-N	97111	(R)-3-((4-(1-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)piperidin- 4-yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A140	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97111	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97111&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2315216	164038355							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130761	O=C1CC[C@@H](Nc2ccc(C3CCN(CC4CCC5(CC4)CN(c4ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc4)C5)CC3)cc2)C(=O)N1	InChI=1S/C46H52N4O4/c51-38-14-15-39-42(26-38)54-28-40(34-4-2-1-3-5-34)44(39)35-8-12-37(13-9-35)50-29-46(30-50)22-18-31(19-23-46)27-49-24-20-33(21-25-49)32-6-10-36(11-7-32)47-41-16-17-43(52)48-45(41)53/h1-15,26,31,33,40-41,44,47,51H,16-25,27-30H2,(H,48,52,53)	FXZDRKDLUPUSJF-UHFFFAOYSA-N	97112	(R)-3-((4-(1-((2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)piperidin- 4-yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A141	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97112	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97112&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2349797	164038356							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130762	O=C1CC[C@H](NC(=O)c2ccc3c(n2)OCC2CN(CC4CCC5(CC4)CN(c4ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc4)C5)CCN32)C(=O)N1	InChI=1S/C46H50N6O6/c53-34-10-11-35-40(22-34)57-26-36(30-4-2-1-3-5-30)42(35)31-6-8-32(9-7-31)51-27-46(28-51)18-16-29(17-19-46)23-50-20-21-52-33(24-50)25-58-45-39(52)14-12-38(48-45)43(55)47-37-13-15-41(54)49-44(37)56/h1-12,14,22,29,33,36-37,42,53H,13,15-21,23-28H2,(H,47,55)(H,49,54,56)	GKZULFGHRFBJMC-UHFFFAOYSA-N	97113	(R)-N-((S)-2,6-dioxopiperidin-3-yl)-3-((2- (4-((3S,4R)-7-hydroxy-3-phenylchroman- 4-yl)phenyl)-2-azaspiro[3.5]nonan-7- yl)methyl)-1,2,3,4,4a,5- hexahydropyrazino[1,2-d]pyrido[2,3- b][1,4]oxazine-8-carboxamide::US20260000676, Compound A142	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97113	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97113&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2368939	164038357							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130763	COc1cc(C(=O)N[C@@H]2CCC(=O)NC2=O)ncc1N1CCN(CC2CCC3(CC2)CN(c2ccc([C@H]4c5ccc(O)cc5OC[C@H]4c4ccccc4)cc2)C3)CC1	InChI=1S/C46H52N6O6/c1-57-41-24-38(45(56)48-37-13-14-42(54)49-44(37)55)47-25-39(41)51-21-19-50(20-22-51)26-30-15-17-46(18-16-30)28-52(29-46)33-9-7-32(8-10-33)43-35-12-11-34(53)23-40(35)58-27-36(43)31-5-3-2-4-6-31/h2-12,23-25,30,36-37,43,53H,13-22,26-29H2,1H3,(H,48,56)(H,49,54,55)	VTECJCSWJYJOBF-UHFFFAOYSA-N	97114	N-((R)-2,6-dioxopiperidin-3-yl)-5-(4-((2- (4-((3R,4S)-7-hydroxy-3-phenylchroman- 4-yl)phenyl)-2-azaspiro[3.5]nonan-7- yl)methyl)piperazin-1-yl)-4- methoxypicolinamide::US20260000676, Compound A144	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97114	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97114&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2327323	164038358							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130764	O=C1CC[C@@H](NC(=O)c2ccc(N3CCN(CC4COC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C4)CC3)cn2)C(=O)N1	InChI=1S/C45H50N6O6/c52-35-11-12-36-40(24-35)56-29-37(31-4-2-1-3-5-31)42(36)32-6-8-33(9-7-32)50-18-16-45(17-19-50)25-30(28-57-45)27-49-20-22-51(23-21-49)34-10-13-38(46-26-34)43(54)47-39-14-15-41(53)48-44(39)55/h1-13,24,26,30,37,39,42,52H,14-23,25,27-29H2,(H,47,54)(H,48,53,55)	ZGGLXGNUSDKTMR-UHFFFAOYSA-N	97115	N-((R)-2,6-dioxopiperidin-3-yl)-5-(4-((8- (4-((3R,4S)-7-hydroxy-3-phenylchroman- 4-yl)phenyl)-1-oxa-8-azaspiro[4.5]decan- 3-yl)methyl)piperazin-1-yl)picolinamide::US20260000676, Compound A145	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97115	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97115&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			4022518	164038359							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130765	O=C1CCC(N2Cc3c(ccc4c3OCC43CCN(CC4COC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C4)CC3)C2=O)C(=O)N1	InChI=1S/C49H52N4O7/c54-35-10-11-37-42(24-35)58-29-39(32-4-2-1-3-5-32)44(37)33-6-8-34(9-7-33)52-22-18-49(19-23-52)25-31(28-60-49)26-51-20-16-48(17-21-51)30-59-45-38-27-53(41-14-15-43(55)50-46(41)56)47(57)36(38)12-13-40(45)48/h1-13,24,31,39,41,44,54H,14-23,25-30H2,(H,50,55,56)	LFJJUGKUGCAABV-UHFFFAOYSA-N	97116	3-(1'-((8-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-1-oxa-8- azaspiro[4.5]decan-3-yl)methyl)-6-oxo- 6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A146	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97116	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97116&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			4969272	164038360							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130766	O=C1CC[C@H](NC(=O)c2ccc3c(n2)OC[C@H]2CN(C[C@H]4COC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CCN32)C(=O)N1	InChI=1S/C46H50N6O7/c53-34-10-11-35-40(22-34)57-28-36(30-4-2-1-3-5-30)42(35)31-6-8-32(9-7-31)51-18-16-46(17-19-51)23-29(26-59-46)24-50-20-21-52-33(25-50)27-58-45-39(52)14-12-38(48-45)43(55)47-37-13-15-41(54)49-44(37)56/h1-12,14,22,29,33,36-37,42,53H,13,15-21,23-28H2,(H,47,55)(H,49,54,56)	JTVVMXJVTIJQEP-UHFFFAOYSA-N	97117	(R)-N-((S)-2,6-dioxopiperidin-3-yl)-3- (((S)-8-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-1-oxa-8- azaspiro[4.5]decan-3-yl)methyl)- 1,2,3,4,4a,5-hexahydropyrazino[1,2- d]pyrido[2,3-b][1,4]oxazine-8- carboxamide::US20260000676, Compound A147	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97117	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97117&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2415722	164038361							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130767	O=C1CC[C@H](NC(=O)c2ccc3c(n2)OC[C@H]2CN(C[C@@H]4COC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CCN32)C(=O)N1	InChI=1S/C46H50N6O7/c53-34-10-11-35-40(22-34)57-28-36(30-4-2-1-3-5-30)42(35)31-6-8-32(9-7-31)51-18-16-46(17-19-51)23-29(26-59-46)24-50-20-21-52-33(25-50)27-58-45-39(52)14-12-38(48-45)43(55)47-37-13-15-41(54)49-44(37)56/h1-12,14,22,29,33,36-37,42,53H,13,15-21,23-28H2,(H,47,55)(H,49,54,56)	JTVVMXJVTIJQEP-UHFFFAOYSA-N	97118	(R)-N-((S)-2,6-dioxopiperidin-3-yl)-3- (((R)-8-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-1-oxa-8- azaspiro[4.5]decan-3-yl)methyl)- 1,2,3,4,4a,5-hexahydropyrazino[1,2- d]pyrido[2,3-b][1,4]oxazine-8- carboxamide::US20260000676, Compound A148	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97118	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97118&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2100274	164038362							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130768	COc1cc(N2CCC(CN3CCC(c4ccc(N[C@@H]5CCC(=O)NC5=O)cc4)CC3)CC2)ccc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C44H50N4O5/c1-52-40-25-34(11-13-36(40)43-37-14-12-35(49)26-41(37)53-28-38(43)32-5-3-2-4-6-32)48-23-17-29(18-24-48)27-47-21-19-31(20-22-47)30-7-9-33(10-8-30)45-39-15-16-42(50)46-44(39)51/h2-14,25-26,29,31,38-39,43,45,49H,15-24,27-28H2,1H3,(H,46,50,51)	OMYSZRUHIMRJIW-UHFFFAOYSA-N	97119	(R)-3-((4-(1-((1-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperidin-4- yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A149	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97119	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97119&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			4008642	164038363							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130769	COc1cc(N2CCC(CN3CCC(c4ccc(N[C@@H]5CCC(=O)NC5=O)cc4)CC3)CC2)ccc1[C@@H]1c2ccc(O)cc2OC[C@@H]1c1ccccc1	InChI=1S/C44H50N4O5/c1-52-40-25-34(11-13-36(40)43-37-14-12-35(49)26-41(37)53-28-38(43)32-5-3-2-4-6-32)48-23-17-29(18-24-48)27-47-21-19-31(20-22-47)30-7-9-33(10-8-30)45-39-15-16-42(50)46-44(39)51/h2-14,25-26,29,31,38-39,43,45,49H,15-24,27-28H2,1H3,(H,46,50,51)	OMYSZRUHIMRJIW-UHFFFAOYSA-N	97120	(R)-3-((4-(1-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperidin-4- yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A150	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97120	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97120&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2559619	164038364							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130770	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3COC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H51N5O7/c54-36-10-11-37-42(21-36)59-29-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-16-14-48(15-17-51)23-30(27-60-48)24-50-18-19-52-35(26-50)28-58-43-22-38-33(20-41(43)52)25-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	NEVLLZDNWSSISS-UHFFFAOYSA-N	97121	(R)-3-((S)-3-(((R)-8-(4-((3R,4S)-7- hydroxy-3-phenylchroman-4-yl)phenyl)-1- oxa-8-azaspiro[4.5]decan-3-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A151	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97121	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97121&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			6902566	164038365							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130771	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3COC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H51N5O7/c54-36-10-11-37-42(21-36)59-29-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-16-14-48(15-17-51)23-30(27-60-48)24-50-18-19-52-35(26-50)28-58-43-22-38-33(20-41(43)52)25-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	NEVLLZDNWSSISS-UHFFFAOYSA-N	97122	(R)-3-((S)-3-(((S)-8-(4-((3R,4S)-7- hydroxy-3-phenylchroman-4-yl)phenyl)-1- oxa-8-azaspiro[4.5]decan-3-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A152	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97122	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97122&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			1599306	164038366							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130772	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OCC42CCN(CC3CCC4(CC3)CN(c3ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc3)C4)CC2)C(=O)N1	InChI=1S/C49H52N4O6/c54-36-10-11-37-42(23-36)58-27-39(32-4-2-1-3-5-32)45(37)33-6-8-35(9-7-33)52-28-48(29-52)16-14-31(15-17-48)25-51-20-18-49(19-21-51)30-59-43-24-38-34(22-40(43)49)26-53(47(38)57)41-12-13-44(55)50-46(41)56/h1-11,22-24,31,39,41,45,54H,12-21,25-30H2,(H,50,55,56)	CMWAKGDTWQNPJP-UHFFFAOYSA-N	97123	(R)-3-(1'-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-7-oxo- 5,7-dihydro-2H,6H-spiro[furo[2,3- f]isoindole-3,4'-piperidin]-6-yl)piperidine- 2,6-dione::US20260000676, Compound A153	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97123	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97123&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			793865	164038367							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130773	O=C1CC[C@@H](N2Cc3c(ccc4c3OCC43CCN(CC4CCC5(CC4)CN(c4ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc4)C5)CC3)C2=O)C(=O)N1	InChI=1S/C49H52N4O6/c54-35-10-11-37-42(24-35)58-27-39(32-4-2-1-3-5-32)44(37)33-6-8-34(9-7-33)52-28-48(29-52)18-16-31(17-19-48)25-51-22-20-49(21-23-51)30-59-45-38-26-53(41-14-15-43(55)50-46(41)56)47(57)36(38)12-13-40(45)49/h1-13,24,31,39,41,44,54H,14-23,25-30H2,(H,50,55,56)	BPZMDXPICADHQA-UHFFFAOYSA-N	97124	(R)-3-(1'-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-6-oxo- 6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A154	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97124	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97124&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			646459	164038368							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130774	O=C1CC[C@@H](N2Cc3c(ccc4c3OC[C@@H]3CN(CC5COC6(CCN(c7ccc([C@H]8c9ccc(O)cc9OC[C@H]8c8ccccc8)cc7F)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H50FN5O7/c49-38-20-31(44-35-8-7-33(55)21-42(35)59-28-37(44)30-4-2-1-3-5-30)6-10-39(38)52-16-14-48(15-17-52)22-29(26-61-48)23-51-18-19-53-32(24-51)27-60-45-36-25-54(41-12-13-43(56)50-46(41)57)47(58)34(36)9-11-40(45)53/h1-11,20-21,29,32,37,41,44,55H,12-19,22-28H2,(H,50,56,57)	SSDFPGXZLUALMG-UHFFFAOYSA-N	97125	(R)-3-((S)-7-(((R)-8-(2-fluoro-4-((3R,4S)- 7-hydroxy-3-phenylchroman-4-yl)phenyl)- 1-oxa-8-azaspiro[4.5]decan-3-yl)methyl)- 1-oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A155	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97125	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97125&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			5337862	164038369							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130775	O=C1CCC(Nc2ccc(C34CCN(CC5COC6(CCN(c7ccc([C@H]8c9ccc(O)cc9OC[C@H]8c8ccccc8)cc7F)CC6)C5)CC3C4(F)F)cc2)C(=O)N1	InChI=1S/C47H49F3N4O5/c48-37-22-31(43-35-12-11-34(55)23-40(35)58-28-36(43)30-4-2-1-3-5-30)6-14-39(37)54-20-16-45(17-21-54)24-29(27-59-45)25-53-19-18-46(41(26-53)47(46,49)50)32-7-9-33(10-8-32)51-38-13-15-42(56)52-44(38)57/h1-12,14,22-23,29,36,38,41,43,51,55H,13,15-21,24-28H2,(H,52,56,57)	PCPLPJSUDQZZKV-UHFFFAOYSA-N	97126	3-((4-(7,7-difluoro-3-(((R)-8-(2-fluoro-4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-3-azabicyclo[4.1.0]heptan-6- yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A156	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97126	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97126&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2811624	164038370							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130776	O=C1CC[C@H](N2Cc3c(ccc4c3OC[C@H]3CN(C[C@@H]5COC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cc7F)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H50FN5O7/c49-38-20-31(44-35-8-7-33(55)21-42(35)59-28-37(44)30-4-2-1-3-5-30)6-10-39(38)52-16-14-48(15-17-52)22-29(26-61-48)23-51-18-19-53-32(24-51)27-60-45-36-25-54(41-12-13-43(56)50-46(41)57)47(58)34(36)9-11-40(45)53/h1-11,20-21,29,32,37,41,44,55H,12-19,22-28H2,(H,50,56,57)	SSDFPGXZLUALMG-UHFFFAOYSA-N	97127	(S)-3-((R)-7-(((R)-8-(2-fluoro-4-((3S,4R)- 7-hydroxy-3-phenylchroman-4-yl)phenyl)- 1-oxa-8-azaspiro[4.5]decan-3-yl)methyl)- 1-oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A157	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97127	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97127&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2795769	164038371							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130777	O=C1CC[C@@H](N2Cc3c(ccc4c3OC[C@@H]3CN(CC5COC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cc7F)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H50FN5O7/c49-38-20-31(44-35-8-7-33(55)21-42(35)59-28-37(44)30-4-2-1-3-5-30)6-10-39(38)52-16-14-48(15-17-52)22-29(26-61-48)23-51-18-19-53-32(24-51)27-60-45-36-25-54(41-12-13-43(56)50-46(41)57)47(58)34(36)9-11-40(45)53/h1-11,20-21,29,32,37,41,44,55H,12-19,22-28H2,(H,50,56,57)	SSDFPGXZLUALMG-UHFFFAOYSA-N	97128	(3R)-3-((5aS)-7-((8-(2-fluoro-4-((3S,4R)- 7-hydroxy-3-phenylchroman-4-yl)phenyl)- 1-oxa-8-azaspiro[4.5]decan-3-yl)methyl)- 1-oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A158	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97128	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97128&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2795678	164038372							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130778	O=C1CCC(Nc2ccc(C34CCN(CC5COC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cc7F)CC6)C5)CC3C4(F)F)cc2)C(=O)N1	InChI=1S/C47H49F3N4O5/c48-37-22-31(43-35-12-11-34(55)23-40(35)58-28-36(43)30-4-2-1-3-5-30)6-14-39(37)54-20-16-45(17-21-54)24-29(27-59-45)25-53-19-18-46(41(26-53)47(46,49)50)32-7-9-33(10-8-32)51-38-13-15-42(56)52-44(38)57/h1-12,14,22-23,29,36,38,41,43,51,55H,13,15-21,24-28H2,(H,52,56,57)	PCPLPJSUDQZZKV-UHFFFAOYSA-N	97129	3-((4-(7,7-difluoro-3-(((R)-8-(2-fluoro-4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-3-azabicyclo[4.1.0]heptan-6- yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A159	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97129	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97129&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2795668	164038373							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130779	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@H]2CN(CC3COC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6F)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H50FN5O7/c49-38-18-31(45-35-8-7-34(55)20-42(35)60-28-37(45)30-4-2-1-3-5-30)6-9-39(38)52-14-12-48(13-15-52)22-29(26-61-48)23-51-16-17-53-33(25-51)27-59-43-21-36-32(19-41(43)53)24-54(47(36)58)40-10-11-44(56)50-46(40)57/h1-9,18-21,29,33,37,40,45,55H,10-17,22-28H2,(H,50,56,57)	YSYNVCGWDVPFCV-UHFFFAOYSA-N	97130	(R)-3-((R)-3-(((R)-8-(2-fluoro-4-((3R,4S)- 7-hydroxy-3-phenylchroman-4-yl)phenyl)- 1-oxa-8-azaspiro[4.5]decan-3-yl)methyl)- 8-oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A160	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97130	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97130&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2800172	164038374							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130780	O=C1CC[C@H](N2Cc3cc4c(cc3C2)N2CCN(CC3COC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6F)CC5)C3)C[C@H]2CO4)C(=O)N1	InChI=1S/C48H52FN5O6/c49-39-18-32(46-37-8-7-36(55)21-43(37)59-29-38(46)31-4-2-1-3-5-31)6-9-40(39)52-14-12-48(13-15-52)22-30(27-60-48)23-51-16-17-54-35(26-51)28-58-44-20-34-25-53(24-33(34)19-42(44)54)41-10-11-45(56)50-47(41)57/h1-9,18-21,30,35,38,41,46,55H,10-17,22-29H2,(H,50,56,57)	WHMXQPDCLNVNDS-UHFFFAOYSA-N	97131	(S)-3-((S)-3-(((R)-8-(2-fluoro-4-((3R,4S)- 7-hydroxy-3-phenylchroman-4-yl)phenyl)- 1-oxa-8-azaspiro[4.5]decan-3-yl)methyl)- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A161	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97131	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97131&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			243725	164038375							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130781	O=C1CC[C@@H](Nc2ccc(C3CCN(C[C@@H]4COC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C4)CC3)c(F)c2)C(=O)N1	InChI=1S/C46H51FN4O5/c47-40-24-34(48-41-14-15-43(53)49-45(41)54)8-12-37(40)32-16-20-50(21-17-32)27-30-26-46(56-28-30)18-22-51(23-19-46)35-9-6-33(7-10-35)44-38-13-11-36(52)25-42(38)55-29-39(44)31-4-2-1-3-5-31/h1-13,24-25,30,32,39,41,44,48,52H,14-23,26-29H2,(H,49,53,54)	SCTCXOJSOHBDIH-UHFFFAOYSA-N	97132	(R)-3-((3-fluoro-4-(1-(((R)-8-(4-((3R,4S)- 7-hydroxy-3-phenylchroman-4-yl)phenyl)- 1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)piperidin-4- yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A162	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97132	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97132&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2738599	164038376							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130782	O=C1CC[C@@H](Nc2ccc(C3CCN(C[C@H]4COC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CC3)c(F)c2)C(=O)N1	InChI=1S/C46H51FN4O5/c47-40-24-34(48-41-14-15-43(53)49-45(41)54)8-12-37(40)32-16-20-50(21-17-32)27-30-26-46(56-28-30)18-22-51(23-19-46)35-9-6-33(7-10-35)44-38-13-11-36(52)25-42(38)55-29-39(44)31-4-2-1-3-5-31/h1-13,24-25,30,32,39,41,44,48,52H,14-23,26-29H2,(H,49,53,54)	SCTCXOJSOHBDIH-UHFFFAOYSA-N	97133	(R)-3-((3-fluoro-4-(1-(((S)-8-(4-((3S,4R)- 7-hydroxy-3-phenylchroman-4-yl)phenyl)- 1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)piperidin-4- yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A163	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97133	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97133&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			2877322	164038377							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130783	O=C1CC[C@@H](Nc2ccc(C3CCN(C[C@H]4COC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C4)CC3)c(F)c2)C(=O)N1	InChI=1S/C46H51FN4O5/c47-40-24-34(48-41-14-15-43(53)49-45(41)54)8-12-37(40)32-16-20-50(21-17-32)27-30-26-46(56-28-30)18-22-51(23-19-46)35-9-6-33(7-10-35)44-38-13-11-36(52)25-42(38)55-29-39(44)31-4-2-1-3-5-31/h1-13,24-25,30,32,39,41,44,48,52H,14-23,26-29H2,(H,49,53,54)	SCTCXOJSOHBDIH-UHFFFAOYSA-N	97134	(R)-3-((3-fluoro-4-(1-(((S)-8-(4-((3R,4S)- 7-hydroxy-3-phenylchroman-4-yl)phenyl)- 1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)piperidin-4- yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A164	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97134	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97134&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			23723905	164038378							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130784	O=C1CC[C@@H](Nc2ccc(C3CCN(C[C@@H]4COC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CC3)c(F)c2)C(=O)N1	InChI=1S/C46H51FN4O5/c47-40-24-34(48-41-14-15-43(53)49-45(41)54)8-12-37(40)32-16-20-50(21-17-32)27-30-26-46(56-28-30)18-22-51(23-19-46)35-9-6-33(7-10-35)44-38-13-11-36(52)25-42(38)55-29-39(44)31-4-2-1-3-5-31/h1-13,24-25,30,32,39,41,44,48,52H,14-23,26-29H2,(H,49,53,54)	SCTCXOJSOHBDIH-UHFFFAOYSA-N	97135	7-hydroxy-3-phenylchroman-4-yl)phenyl)- 1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)piperidin-4- yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A165	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97135	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97135&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			4573346	164038379							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
130785	O=C1CCC(N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C45H47N5O6/c51-33-10-11-35-40(22-33)55-27-37(29-4-2-1-3-5-29)42(35)30-6-8-31(9-7-30)48-18-16-28(17-19-48)23-47-20-21-49-32(24-47)26-56-43-36-25-50(39-14-15-41(52)46-44(39)53)45(54)34(36)12-13-38(43)49/h1-13,22,28,32,37,39,42,51H,14-21,23-27H2,(H,46,52,53)	PKHVPEPQVNTSRM-UHFFFAOYSA-N	96977	3-((R)-7-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)-1-oxo-1,3,5,5a,6,7,8,9- octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A8	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96977	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96977&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			16188876	164038221							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130786	O=C1CCC(N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6F)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C45H46FN5O6/c46-36-20-29(42-33-8-7-31(52)21-40(33)56-26-35(42)28-4-2-1-3-5-28)6-10-37(36)49-16-14-27(15-17-49)22-48-18-19-50-30(23-48)25-57-43-34-24-51(39-12-13-41(53)47-44(39)54)45(55)32(34)9-11-38(43)50/h1-11,20-21,27,30,35,39,42,52H,12-19,22-26H2,(H,47,53,54)	WIZNLEVXEOBIOP-UHFFFAOYSA-N	96978	3-((R)-7-((1-(2-fluoro-4-((3S,4R)-7- hydroxy-3-phenylchroman-4- yl)phenyl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A9	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96978	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96978&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			975007	164038222							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130787	O=C1CCC(N2Cc3c(ccc4c3OC[C@@H]3CN(CC5CC6(CCN(c7ccc([C@H]8c9ccc(O)cc9OC[C@H]8c8ccccc8)cc7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O6/c54-35-10-11-37-42(22-35)58-29-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-18-16-48(17-19-51)23-30(24-48)25-50-20-21-52-34(26-50)28-59-45-38-27-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	SSNYEZAYMZGQKT-UHFFFAOYSA-N	96990	3-((S)-7-((7-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A21	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96990	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96990&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			2086196	164038234							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130788	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CC3(CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC3)C2)C4)C(=O)N1	InChI=1S/C45H43N5O7/c51-32-10-11-33-38(20-32)57-24-36(27-4-2-1-3-5-27)41(33)28-6-8-31(9-7-28)48-16-14-45(15-17-48)25-49(26-45)40(53)23-47-21-29-18-34-35(19-30(29)22-47)44(56)50(43(34)55)37-12-13-39(52)46-42(37)54/h1-11,18-20,36-37,41,51H,12-17,21-26H2,(H,46,52,54)	JPEBSIKGHPZPGX-UHFFFAOYSA-N	96995	2-(2,6-dioxopiperidin-3-yl)-6-(2-(7-(4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-2,7-diazaspiro[3.5]nonan-2-yl)- 2-oxoethyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A26	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96995	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96995&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			691782	164038239							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130789	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-29-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-16-14-48(15-17-51)23-30(24-48)25-50-18-19-52-35(27-50)28-58-43-22-38-33(20-41(43)52)26-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	JGUADLWFBMOXGP-UHFFFAOYSA-N	96996	3-((S)-3-((7-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A27	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96996	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96996&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			3781132	164038240							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130790	O=C1CCC(N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCN(c6ncc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cn6)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C43H45N7O6/c51-30-6-7-32-37(18-30)55-25-34(27-4-2-1-3-5-27)39(32)28-19-44-43(45-20-28)48-14-12-26(13-15-48)21-47-16-17-49-29(22-47)24-56-40-33-23-50(36-10-11-38(52)46-41(36)53)42(54)31(33)8-9-35(40)49/h1-9,18-20,26,29,34,36,39,51H,10-17,21-25H2,(H,46,52,53)	RPFWZHFAZYZAOK-UHFFFAOYSA-N	97004	3-((R)-7-((1-(5-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)pyrimidin-2- yl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- elisoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A35	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97004	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97004&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			3453546	164038248							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130791	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CCC3(CC2)CCN(c2ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc2)CC3)C4)C(=O)N1	InChI=1S/C47H47N5O7/c53-34-10-11-35-40(24-34)59-28-38(29-4-2-1-3-5-29)43(35)30-6-8-33(9-7-30)50-18-14-47(15-19-50)16-20-51(21-17-47)42(55)27-49-25-31-22-36-37(23-32(31)26-49)46(58)52(45(36)57)39-12-13-41(54)48-44(39)56/h1-11,22-24,38-39,43,53H,12-21,25-28H2,(H,48,54,56)	YDMQYRRRRMPTJD-UHFFFAOYSA-N	97010	2-(2,6-dioxopiperidin-3-yl)-6-(2-(9-(4- ((3R,4S)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-3,9-diazaspiro[5.5]undecan-3- yl)-2-oxoethyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A40	Steroid hormone receptor ERR1 LBD	Homo sapiens		>5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97010	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97010&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			1854166	164038254							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130792	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CCC3(CC2)CCN(c2ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc2)CC3)C4)C(=O)N1	InChI=1S/C47H49N5O6/c53-36-10-11-37-41(24-36)58-29-39(30-4-2-1-3-5-30)44(37)31-6-8-35(9-7-31)50-20-16-47(17-21-50)14-18-49(19-15-47)28-43(55)51-25-32-22-34-27-52(40-12-13-42(54)48-45(40)56)46(57)38(34)23-33(32)26-51/h1-11,22-24,39-40,44,53H,12-21,25-29H2,(H,48,54,56)	WFNJFSDLQSHAAO-UHFFFAOYSA-N	97011	(R)-3-(6-(2-(9-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-3,9- diazaspiro[5.5]undecan-3-yl)acetyl)-1- oxo-3,5,6,7-tetrahydropyrrolo[3,4- f]isoindol-2(1H)-yl)piperidine-2,6-dione::US20260000676, Compound A41	Steroid hormone receptor ERR1 LBD	Homo sapiens		>5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97011	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97011&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			5454863	164038255							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130793	O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CCC3(CC2)CN(c2ccc([C@@H]5c6ccc(O)cc6OC[C@@H]5c5ccccc5)cc2)C3)C4)C(=O)N1	InChI=1S/C45H43N5O7/c51-32-10-11-33-38(20-32)57-24-36(27-4-2-1-3-5-27)41(33)28-6-8-31(9-7-28)49-25-45(26-49)14-16-48(17-15-45)40(53)23-47-21-29-18-34-35(19-30(29)22-47)44(56)50(43(34)55)37-12-13-39(52)46-42(37)54/h1-11,18-20,36-37,41,51H,12-17,21-26H2,(H,46,52,54)	BXVMSRJPFSOBKE-UHFFFAOYSA-N	97014	2-(2,6-dioxopiperidin-3-yl)-6-(2-(2-(4- ((3S,4R)-7-hydroxy-3-phenylchroman-4- yl)phenyl)-2,7-diazaspiro[3.5]nonan-7-yl)- 2-oxoethyl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260000676, Compound A44	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97014&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			2586218	164038258							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130794	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CCC3(CC2)CN(c2ccc([C@@H]5c6ccc(O)cc6OC[C@@H]5c5ccccc5)cc2)C3)C4)C(=O)N1	InChI=1S/C45H45N5O6/c51-34-10-11-35-39(20-34)56-25-37(28-4-2-1-3-5-28)42(35)29-6-8-33(9-7-29)49-26-45(27-49)14-16-47(17-15-45)24-41(53)48-21-30-18-32-23-50(38-12-13-40(52)46-43(38)54)44(55)36(32)19-31(30)22-48/h1-11,18-20,37-38,42,51H,12-17,21-27H2,(H,46,52,54)	YIVSKZUSEWEYQU-UHFFFAOYSA-N	97019	3-(6-(2-(2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2,7- diazaspiro[3.5]nonan-7-yl)acetyl)-1-oxo- 3,5,6,7-tetrahydropyrrolo[3,4-f]isoindol- 2(1H)-yl)piperidine-2,6-dione::US20260000676, Compound A49	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97019	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97019&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			2482686	164038263							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130795	O=C1CC[C@H](N2Cc3c(ccc4c3OC[C@H]3CN(CC5CC6(CCN(c7ccc([C@H]8c9ccc(O)cc9OC[C@H]8c8ccccc8)cc7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O6/c54-35-10-11-37-42(22-35)58-29-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-18-16-48(17-19-51)23-30(24-48)25-50-20-21-52-34(26-50)28-59-45-38-27-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	SSNYEZAYMZGQKT-UHFFFAOYSA-N	97021	(S)-3-((R)-7-((7-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A50	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97021&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			28803	164038265							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130796	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCC5(CC3)CN(c3ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc3)C5)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-27-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-28-48(29-51)16-14-30(15-17-48)23-50-18-19-52-35(25-50)26-58-43-22-38-33(20-41(43)52)24-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	IKGGCVYEWPPTHT-UHFFFAOYSA-N	97024	3-((S)-3-((2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A53	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97024	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97024&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			22694	164038268							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130797	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CC3(CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC3)C2)C4)C(=O)N1	InChI=1S/C45H45N5O6/c51-34-10-11-35-39(20-34)56-25-37(28-4-2-1-3-5-28)42(35)29-6-8-33(9-7-29)48-16-14-45(15-17-48)26-47(27-45)24-41(53)49-21-30-18-32-23-50(38-12-13-40(52)46-43(38)54)44(55)36(32)19-31(30)22-49/h1-11,18-20,37-38,42,51H,12-17,21-27H2,(H,46,52,54)	RNNMVVNAVASCCO-UHFFFAOYSA-N	97027	3-(6-(2-(7-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2,7- diazaspiro[3.5]nonan-2-yl)acetyl)-1-oxo- 3,5,6,7-tetrahydropyrrolo[3,4-f]isoindol- 2(1H)-yl)piperidine-2,6-dione formate::US20260000676, Compound A56	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97027&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			270861	164038271							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130798	O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCC5(CC3)CN(c3ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc3)C5)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-27-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-28-48(29-51)16-14-30(15-17-48)23-50-18-19-52-35(25-50)26-58-43-22-38-33(20-41(43)52)24-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	IKGGCVYEWPPTHT-UHFFFAOYSA-N	97030	3-((S)-3-((2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A58	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97030	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97030&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			289018	164038274							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130799	O=C1CC[C@H](N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-29-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-16-14-48(15-17-51)23-30(24-48)25-50-18-19-52-35(27-50)28-58-43-22-38-33(20-41(43)52)26-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	JGUADLWFBMOXGP-UHFFFAOYSA-N	97031	(S)-3-((S)-3-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A59	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97031&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			498990	164038275							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130800	O=C9CCC(N8Cc7cc(N6CCN(CC5CCN(c4ccc([C@@H]2c1ccc(O)cc1OC[C@@H]2c3ccccc3)cc4)CC5)CC6)ccc7C8=O)C(=O)N9	InChI=1S/C45H49N5O4/c1-30-7-16-41(44(52)46-30)50-28-34-25-36(12-14-38(34)45(50)53)49-23-21-47(22-24-49)27-31-17-19-48(20-18-31)35-10-8-33(9-11-35)43-39-15-13-37(51)26-42(39)54-29-40(43)32-5-3-2-4-6-32/h2-6,8-15,25-26,31,40-41,43,51H,1,7,16-24,27-29H2,(H,46,52)	QSRYPADAZHLZSE-UHFFFAOYSA-N	97035	3-(5-(4-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)piperazin-1-yl)-1-oxoisoindolin- 2-yl)piperidine-2,6-dione::US20260000676, Compound A62	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97035	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97035&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			280899	164038279							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130801	O=C1CCC(N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cn6)CC5)CCN43)C2=O)C(=O)N1	InChI=1S/C44H46N6O6/c51-31-7-8-33-38(20-31)55-26-35(28-4-2-1-3-5-28)41(33)29-6-12-39(45-21-29)48-16-14-27(15-17-48)22-47-18-19-49-30(23-47)25-56-42-34-24-50(37-11-13-40(52)46-43(37)53)44(54)32(34)9-10-36(42)49/h1-10,12,20-21,27,30,35,37,41,51H,11,13-19,22-26H2,(H,46,52,53)	SHCBRAIXQDZAEO-UHFFFAOYSA-N	97037	3-((R)-7-((1-(5-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)pyridin-2- yl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A64	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97037	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97037&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			49778889	164038281					C06049		1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130802	O=C1CCC(C2Cc3c(ccc4c3OC[C@H]3CN(CC5CC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cn7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O6/c54-33-7-8-36-41(20-33)58-28-39(30-4-2-1-3-5-30)44(36)31-6-12-42(49-24-31)52-16-14-48(15-17-52)22-29(23-48)25-51-18-19-53-32(26-51)27-59-46-38-21-37(35-10-13-43(55)50-47(35)57)45(56)34(38)9-11-40(46)53/h1-9,11-12,20,24,29,32,35,37,39,44,54H,10,13-19,21-23,25-28H2,(H,50,55,57)	OLIMOMUHMQFDSE-UHFFFAOYSA-N	97136	3-((R)-7-((7-(5-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)pyridin-2-yl)-7- azaspiro[3.5]nonan-2-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A66	Steroid hormone receptor ERR1 LBD	Homo sapiens		>5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97136	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97136&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			1095440	164038380							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130803	O=C1CCC(N2Cc3cc(N4CCN(CC5CC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cn7)CC6)C5)CC4)ccc3C2=O)C(=O)N1	InChI=1S/C46H50N6O5/c53-35-8-10-37-40(23-35)57-29-38(31-4-2-1-3-5-31)43(37)32-6-12-41(47-26-32)51-16-14-46(15-17-51)24-30(25-46)27-49-18-20-50(21-19-49)34-7-9-36-33(22-34)28-52(45(36)56)39-11-13-42(54)48-44(39)55/h1-10,12,22-23,26,30,38-39,43,53H,11,13-21,24-25,27-29H2,(H,48,54,55)	MOXUHRVGVLTQQM-UHFFFAOYSA-N	97137	3-(5-(4-((7-(5-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)pyridin-2-yl)-7-azaspiro [3.5]nonan-2-yl)methyl)piperazin-1-yl)-1- oxoisoindolin-2-yl)piperidine-2,6-dione::US20260000676, Compound A68	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97137	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97137&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			2139165	164038381							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130804	COc1cc(N2CCC(CN3CCN4c5ccc6c(c5OC[C@H]4C3)CN(C3CCC(=O)NC3=O)C6=O)CC2)ccc1[C@@H]1c2ccc(O)cc2OC[C@@H]1c1ccccc1	InChI=1S/C46H49N5O7/c1-56-40-21-30(7-9-34(40)43-35-10-8-32(52)22-41(35)57-27-37(43)29-5-3-2-4-6-29)49-17-15-28(16-18-49)23-48-19-20-50-31(24-48)26-58-44-36-25-51(39-13-14-42(53)47-45(39)54)46(55)33(36)11-12-38(44)50/h2-12,21-22,28,31,37,39,43,52H,13-20,23-27H2,1H3,(H,47,53,54)	KFOQSSLNXOAYPF-UHFFFAOYSA-N	97048	3-((R)-7-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A77	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97048&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			51361437	164038292							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130805	O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)C2CCN(C3CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC3)CC2)C4)C(=O)N1	InChI=1S/C47H49N5O6/c53-37-10-11-38-42(24-37)58-28-40(29-4-2-1-3-5-29)44(38)30-6-8-35(9-7-30)50-20-16-36(17-21-50)49-18-14-31(15-19-49)46(56)51-25-32-22-34-27-52(41-12-13-43(54)48-45(41)55)47(57)39(34)23-33(32)26-51/h1-11,22-24,31,36,40-41,44,53H,12-21,25-28H2,(H,48,54,55)	YJWSVXDJVCMWPI-UHFFFAOYSA-N	97052	3-(6-(1'-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-[1,4'- bipiperidine]-4-carbonyl)-1-oxo-3,5,6,7- tetrahydropyrrolo[3,4-f]isoindol-2(1H)- yl)piperidine-2,6-dione::US20260000676, Compound A81	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97052&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			53383134	164038296							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130806	COc1cc(N2CCC(CN3CCN4c5cc6c(cc5OC[C@H]4C3)C(=O)N(C3CCC(=O)NC3=O)C6)CC2)ccc1[C@@H]1c2ccc(O)cc2OC[C@@H]1c1ccccc1	InChI=1S/C46H49N5O7/c1-56-40-20-31(7-9-34(40)44-35-10-8-33(52)21-41(35)58-27-37(44)29-5-3-2-4-6-29)49-15-13-28(14-16-49)23-48-17-18-50-32(25-48)26-57-42-22-36-30(19-39(42)50)24-51(46(36)55)38-11-12-43(53)47-45(38)54/h2-10,19-22,28,32,37-38,44,52H,11-18,23-27H2,1H3,(H,47,53,54)	FAZUJCHEBBDOGY-UHFFFAOYSA-N	97055	3-((R)-3-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A84	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97055&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			646580	164038299							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130807	O=C1CCC(N2Cc3cc4c(cc3C2=O)OCC42CCN(CC3CCC4(CC3)CN(c3ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc3)C4)CC2)C(=O)N1	InChI=1S/C49H52N4O6/c54-36-10-11-37-42(23-36)58-27-39(32-4-2-1-3-5-32)45(37)33-6-8-35(9-7-33)52-28-48(29-52)16-14-31(15-17-48)25-51-20-18-49(19-21-51)30-59-43-24-38-34(22-40(43)49)26-53(47(38)57)41-12-13-44(55)50-46(41)56/h1-11,22-24,31,39,41,45,54H,12-21,25-30H2,(H,50,55,56)	CMWAKGDTWQNPJP-UHFFFAOYSA-N	97070	3-(1'-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-7-oxo- 5,7-dihydro-2H,6H-spiro[furo[2,3- f]isoindole-3,4'-piperidin]-6-yl)piperidine- 2,6-dione::US20260000676, Compound A99	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97070	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97070&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			1254286	164038314							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130808	COc1cc(N2CCC(CN3CCN4c5ccc6c(c5OC[C@@H]4C3)CN([C@@H]3CCC(=O)NC3=O)C6=O)CC2)c(F)cc1[C@@H]1c2ccc(O)cc2OC[C@@H]1c1ccccc1	InChI=1S/C46H48FN5O7/c1-57-40-21-39(36(47)20-33(40)43-32-8-7-30(53)19-41(32)58-26-35(43)28-5-3-2-4-6-28)50-15-13-27(14-16-50)22-49-17-18-51-29(23-49)25-59-44-34-24-52(38-11-12-42(54)48-45(38)55)46(56)31(34)9-10-37(44)51/h2-10,19-21,27,29,35,38,43,53H,11-18,22-26H2,1H3,(H,48,54,55)	ABYHVQGAUUOKSI-UHFFFAOYSA-N	97078	(R)-3-((S)-7-((1-(2-fluoro-4-((3S,4S)-7- hydroxy-3-phenylchroman-4-yl)-5- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A106	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97078	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97078&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			20231	164038322							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130809	COc1cc(N2CCC(CN3CCN(c4ccc(C(=O)NC5CCC(=O)NC5=O)nc4)CC3)CC2)c(F)cc1[C@H]1c2ccc(O)cc2CC[C@H]1c1ccccc1	InChI=1S/C44H49FN6O5/c1-56-40-25-39(36(45)24-35(40)42-33(29-5-3-2-4-6-29)10-7-30-23-32(52)9-11-34(30)42)51-17-15-28(16-18-51)27-49-19-21-50(22-20-49)31-8-12-37(46-26-31)43(54)47-38-13-14-41(53)48-44(38)55/h2-6,8-9,11-12,23-26,28,33,38,42,52H,7,10,13-22,27H2,1H3,(H,47,54)(H,48,53,55)	YMILKCLHVQTTEF-UHFFFAOYSA-N	97082	N-(2,6-dioxopiperidin-3-yl)-5-(4-((1-(2- fluoro-4-((3R,4R)-7-hydroxy-3- phenylchroman-4-yl)-5- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)picolinamide::US20260000676, Compound A110	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97082	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97082&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			1952659	164038326							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130810	O=C1CCC(N2Cc3c(ccc4c3OCC43CCN(CC4CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CC3)C2=O)C(=O)N1	InChI=1S/C49H52N4O6/c54-35-10-11-37-42(24-35)58-29-39(32-4-2-1-3-5-32)44(37)33-6-8-34(9-7-33)52-22-16-48(17-23-52)25-31(26-48)27-51-20-18-49(19-21-51)30-59-45-38-28-53(41-14-15-43(55)50-46(41)56)47(57)36(38)12-13-40(45)49/h1-13,24,31,39,41,44,54H,14-23,25-30H2,(H,50,55,56)	BUNBYWKAYABLSW-UHFFFAOYSA-N	97084	3-(1'-((7-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-7- azaspiro[3.5]nonan-2-yl)methyl)-6-oxo- 6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A113	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97084	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97084&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			5517556	164038328							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130811	O=C1CCC(N2Cc3c(ccc4c3OCC43CCN(CC4CCC5(CC4)CN(c4ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc4)C5)CC3)C2=O)C(=O)N1	InChI=1S/C49H52N4O6/c54-35-10-11-37-42(24-35)58-27-39(32-4-2-1-3-5-32)44(37)33-6-8-34(9-7-33)52-28-48(29-52)18-16-31(17-19-48)25-51-22-20-49(21-23-51)30-59-45-38-26-53(41-14-15-43(55)50-46(41)56)47(57)36(38)12-13-40(45)49/h1-13,24,31,39,41,44,54H,14-23,25-30H2,(H,50,55,56)	BPZMDXPICADHQA-UHFFFAOYSA-N	97085	3-(1'-((2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-6-oxo- 6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A114	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97085	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97085&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			5613808	164038329							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130812	O=C1CC[C@H](N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCC6(CC5)CN(c5ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc5)C6)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O6/c54-35-10-11-37-42(22-35)58-27-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-28-48(29-51)18-16-30(17-19-48)23-50-20-21-52-34(24-50)26-59-45-38-25-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	VMPKZWYOZWRHDR-UHFFFAOYSA-N	97086	(S)-3-((R)-7-((2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A115	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97086	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97086&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			6906133	164038330							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130813	COc1cc(C(=O)NC2CCC(=O)NC2=O)ncc1N1CCN(CC2CCC3(CC2)CN(c2ccc([C@H]4c5ccc(O)cc5OC[C@H]4c4ccccc4)cc2)C3)CC1	InChI=1S/C46H52N6O6/c1-57-41-24-38(45(56)48-37-13-14-42(54)49-44(37)55)47-25-39(41)51-21-19-50(20-22-51)26-30-15-17-46(18-16-30)28-52(29-46)33-9-7-32(8-10-33)43-35-12-11-34(53)23-40(35)58-27-36(43)31-5-3-2-4-6-31/h2-12,23-25,30,36-37,43,53H,13-22,26-29H2,1H3,(H,48,56)(H,49,54,55)	VTECJCSWJYJOBF-UHFFFAOYSA-N	97088	rac-N-(2,6-dioxopiperidin-3-yl)-5-(4-((2- (4-((3R,4S)-7-hydroxy-3-phenylchroman- 4-yl)phenyl)-2-azaspiro[3.5]nonan-7- yl)methyl)piperazin-1-yl)-4- methoxypicolinamide::US20260000676, Compound A117	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97088	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97088&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			4544702	164038332							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130814	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@H]2CN(CC3CCC5(CC3)CN(c3ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc3)C5)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-27-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-28-48(29-51)16-14-30(15-17-48)23-50-18-19-52-35(25-50)26-58-43-22-38-33(20-41(43)52)24-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	IKGGCVYEWPPTHT-UHFFFAOYSA-N	97089	(R)-3-((R)-3-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A118	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97089	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97089&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			1321677	164038333							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130815	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCC5(CC3)CN(c3ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc3)C5)CCN42)C(=O)N1	InChI=1S/C48H51N5O6/c54-36-10-11-37-42(21-36)59-27-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-28-48(29-51)16-14-30(15-17-48)23-50-18-19-52-35(25-50)26-58-43-22-38-33(20-41(43)52)24-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	IKGGCVYEWPPTHT-UHFFFAOYSA-N	97091	(R)-3-((S)-3-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A120	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97091	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97091&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			1211814	164038335							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130816	COc1cc(N2CCC(CN3CCN4c5ccc6c(c5OC[C@@H]4C3)CN([C@@H]3CCC(=O)NC3=O)C6=O)CC2)ccc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C46H49N5O7/c1-56-40-21-30(7-9-34(40)43-35-10-8-32(52)22-41(35)57-27-37(43)29-5-3-2-4-6-29)49-17-15-28(16-18-49)23-48-19-20-50-31(24-48)26-58-44-36-25-51(39-13-14-42(53)47-45(39)54)46(55)33(36)11-12-38(44)50/h2-12,21-22,28,31,37,39,43,52H,13-20,23-27H2,1H3,(H,47,53,54)	KFOQSSLNXOAYPF-UHFFFAOYSA-N	97092	(R)-3-((S)-7-((1-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A121	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97092	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97092&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			787494	164038336							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130817	COc1cc(N2CCC(CN3CCN4c5cc6c(cc5OC[C@H]4C3)C(=O)N([C@@H]3CCC(=O)NC3=O)C6)CC2)ccc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C46H49N5O7/c1-56-40-20-31(7-9-34(40)44-35-10-8-33(52)21-41(35)58-27-37(44)29-5-3-2-4-6-29)49-15-13-28(14-16-49)23-48-17-18-50-32(25-48)26-57-42-22-36-30(19-39(42)50)24-51(46(36)55)38-11-12-43(53)47-45(38)54/h2-10,19-22,28,32,37-38,44,52H,11-18,23-27H2,1H3,(H,47,53,54)	FAZUJCHEBBDOGY-UHFFFAOYSA-N	97093	(R)-3-((R)-3-((1-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A122	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97093	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97093&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			5604202	164038337							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130818	COc1cc(N2CCC3(CC2)CC(CN2CCN4c5ccc6c(c5OC[C@@H]4C2)CN([C@@H]2CCC(=O)NC2=O)C6=O)C3)c(F)cc1[C@@H]1c2ccc(O)cc2OC[C@@H]1c1ccccc1	InChI=1S/C49H52FN5O7/c1-60-42-21-41(38(50)20-35(42)45-34-8-7-32(56)19-43(34)61-28-37(45)30-5-3-2-4-6-30)53-15-13-49(14-16-53)22-29(23-49)24-52-17-18-54-31(25-52)27-62-46-36-26-55(40-11-12-44(57)51-47(40)58)48(59)33(36)9-10-39(46)54/h2-10,19-21,29,31,37,40,45,56H,11-18,22-28H2,1H3,(H,51,57,58)	RRPOCDMJIPJJHE-UHFFFAOYSA-N	97096	(R)-3-((S)-7-((7-(2-fluoro-4-((3S,4S)-7- hydroxy-3-phenylchroman-4-yl)-5- methoxyphenyl)-7-azaspiro[3.5]nonan-2- yl)methyl)-1-oxo-1,3,5,5a,6,7,8,9- octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A125	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97096	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97096&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			2240759	164038340							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130819	COc1cc(N2CCC3(CC2)CC(CN2CCC4(CC2)COc2c4ccc4c2CN(C2CCC(=O)NC2=O)C4=O)C3)c(F)cc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1	InChI=1S/C50H53FN4O7/c1-60-42-23-41(39(51)22-35(42)45-34-8-7-32(56)21-43(34)61-28-37(45)31-5-3-2-4-6-31)54-19-13-49(14-20-54)24-30(25-49)26-53-17-15-50(16-18-53)29-62-46-36-27-55(40-11-12-44(57)52-47(40)58)48(59)33(36)9-10-38(46)50/h2-10,21-23,30,37,40,45,56H,11-20,24-29H2,1H3,(H,52,57,58)	STVVTUOREOYWID-UHFFFAOYSA-N	97101	3-(1'-((7-(2-fluoro-4-((3R,4R)-7-hydroxy- 3-phenylchroman-4-yl)-5- methoxyphenyl)-7-azaspiro[3.5]nonan-2- yl)methyl)-6-oxo-6,8-dihydro-2H,7H- spiro[furo[2,3-e]isoindole-3,4'-piperidin]- 7-yl)piperidine-2,6-dione::US20260000676, Compound A130	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97101	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97101&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			1126136	164038345							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130820	O=C1CC[C@@H](N2Cc3c(ccc4c3OC[C@@H]3CN(C[C@@H]5COC6(CCN(c7ccc([C@H]8c9ccc(O)cc9OC[C@H]8c8ccccc8)cc7)CC6)C5)CCN43)C2=O)C(=O)N1	InChI=1S/C48H51N5O7/c54-35-10-11-37-42(22-35)58-29-39(31-4-2-1-3-5-31)44(37)32-6-8-33(9-7-32)51-18-16-48(17-19-51)23-30(27-60-48)24-50-20-21-52-34(25-50)28-59-45-38-26-53(41-14-15-43(55)49-46(41)56)47(57)36(38)12-13-40(45)52/h1-13,22,30,34,39,41,44,54H,14-21,23-29H2,(H,49,55,56)	NGKUCSTXXZJYFQ-UHFFFAOYSA-N	97103	(R)-3-((S)-7-(((R)-8-(4-((3R,4S)-7- hydroxy-3-phenylchroman-4-yl)phenyl)-1- oxa-8-azaspiro[4.5]dccan-3-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A132	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97103	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97103&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			4157793	164038347							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130821	O=C1CCC(N2Cc3ccc4c(c3C2=O)OCC42CCN(CC3COC4(CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC4)C3)CC2)C(=O)N1	InChI=1S/C49H52N4O7/c54-36-11-12-37-41(24-36)58-29-38(32-4-2-1-3-5-32)43(37)33-6-9-35(10-7-33)52-22-18-49(19-23-52)25-31(28-60-49)26-51-20-16-48(17-21-51)30-59-45-39(48)13-8-34-27-53(47(57)44(34)45)40-14-15-42(55)50-46(40)56/h1-13,24,31,38,40,43,54H,14-23,25-30H2,(H,50,55,56)	QCJKIAQNQAZEPK-UHFFFAOYSA-N	97108	3-(1'-((8-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-1-oxa-8- azaspiro[4.5]decan-3-yl)methyl)-6-oxo- 6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A137	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97108	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97108&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			2100093	164038352							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130822	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OC[C@H]2CN(CC3COC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C3)CCN42)C(=O)N1	InChI=1S/C48H51N5O7/c54-36-10-11-37-42(21-36)59-29-39(31-4-2-1-3-5-31)45(37)32-6-8-34(9-7-32)51-16-14-48(15-17-51)23-30(27-60-48)24-50-18-19-52-35(26-50)28-58-43-22-38-33(20-41(43)52)25-53(47(38)57)40-12-13-44(55)49-46(40)56/h1-11,20-22,30,35,39-40,45,54H,12-19,23-29H2,(H,49,55,56)	NEVLLZDNWSSISS-UHFFFAOYSA-N	97109	(3R)-3-((4aR)-3-((8-(4-((3R,4S)-7- hydroxy-3-phenylchroman-4-yl)phenyl)-1- oxa-8-azaspiro[4.5]decan-3-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260000676, Compound A138	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97109	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97109&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			2508533	164038353							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130823	O=C1CC[C@@H](Nc2ccc(C3CCN(CC4CCC5(CC4)CN(c4ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc4)C5)CC3)cc2)C(=O)N1	InChI=1S/C46H52N4O4/c51-38-14-15-39-42(26-38)54-28-40(34-4-2-1-3-5-34)44(39)35-8-12-37(13-9-35)50-29-46(30-50)22-18-31(19-23-46)27-49-24-20-33(21-25-49)32-6-10-36(11-7-32)47-41-16-17-43(52)48-45(41)53/h1-15,26,31,33,40-41,44,47,51H,16-25,27-30H2,(H,48,52,53)	FXZDRKDLUPUSJF-UHFFFAOYSA-N	97111	(R)-3-((4-(1-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)piperidin- 4-yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A140	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97111	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97111&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			2315216	164038355							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130824	O=C1CC[C@H](NC(=O)c2ccc3c(n2)OCC2CN(CC4CCC5(CC4)CN(c4ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc4)C5)CCN32)C(=O)N1	InChI=1S/C46H50N6O6/c53-34-10-11-35-40(22-34)57-26-36(30-4-2-1-3-5-30)42(35)31-6-8-32(9-7-31)51-27-46(28-51)18-16-29(17-19-46)23-50-20-21-52-33(24-50)25-58-45-39(52)14-12-38(48-45)43(55)47-37-13-15-41(54)49-44(37)56/h1-12,14,22,29,33,36-37,42,53H,13,15-21,23-28H2,(H,47,55)(H,49,54,56)	GKZULFGHRFBJMC-UHFFFAOYSA-N	97113	(R)-N-((S)-2,6-dioxopiperidin-3-yl)-3-((2- (4-((3S,4R)-7-hydroxy-3-phenylchroman- 4-yl)phenyl)-2-azaspiro[3.5]nonan-7- yl)methyl)-1,2,3,4,4a,5- hexahydropyrazino[1,2-d]pyrido[2,3- b][1,4]oxazine-8-carboxamide::US20260000676, Compound A142	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97113	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97113&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			2368939	164038357							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130825	O=C1CC[C@@H](NC(=O)c2ccc(N3CCN(CC4COC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C4)CC3)cn2)C(=O)N1	InChI=1S/C45H50N6O6/c52-35-11-12-36-40(24-35)56-29-37(31-4-2-1-3-5-31)42(36)32-6-8-33(9-7-32)50-18-16-45(17-19-50)25-30(28-57-45)27-49-20-22-51(23-21-49)34-10-13-38(46-26-34)43(54)47-39-14-15-41(53)48-44(39)55/h1-13,24,26,30,37,39,42,52H,14-23,25,27-29H2,(H,47,54)(H,48,53,55)	ZGGLXGNUSDKTMR-UHFFFAOYSA-N	97115	N-((R)-2,6-dioxopiperidin-3-yl)-5-(4-((8- (4-((3R,4S)-7-hydroxy-3-phenylchroman- 4-yl)phenyl)-1-oxa-8-azaspiro[4.5]decan- 3-yl)methyl)piperazin-1-yl)picolinamide::US20260000676, Compound A145	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97115	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97115&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			4022518	164038359							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130826	O=C1CCC(N2Cc3c(ccc4c3OCC43CCN(CC4COC5(CCN(c6ccc([C@H]7c8ccc(O)cc8OC[C@H]7c7ccccc7)cc6)CC5)C4)CC3)C2=O)C(=O)N1	InChI=1S/C49H52N4O7/c54-35-10-11-37-42(24-35)58-29-39(32-4-2-1-3-5-32)44(37)33-6-8-34(9-7-33)52-22-18-49(19-23-52)25-31(28-60-49)26-51-20-16-48(17-21-51)30-59-45-38-27-53(41-14-15-43(55)50-46(41)56)47(57)36(38)12-13-40(45)48/h1-13,24,31,39,41,44,54H,14-23,25-30H2,(H,50,55,56)	LFJJUGKUGCAABV-UHFFFAOYSA-N	97116	3-(1'-((8-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-1-oxa-8- azaspiro[4.5]decan-3-yl)methyl)-6-oxo- 6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A146	Steroid hormone receptor ERR1 LBD	Homo sapiens		>5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97116	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97116&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			4969272	164038360							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130827	O=C1CC[C@H](NC(=O)c2ccc3c(n2)OC[C@H]2CN(C[C@H]4COC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CCN32)C(=O)N1	InChI=1S/C46H50N6O7/c53-34-10-11-35-40(22-34)57-28-36(30-4-2-1-3-5-30)42(35)31-6-8-32(9-7-31)51-18-16-46(17-19-51)23-29(26-59-46)24-50-20-21-52-33(25-50)27-58-45-39(52)14-12-38(48-45)43(55)47-37-13-15-41(54)49-44(37)56/h1-12,14,22,29,33,36-37,42,53H,13,15-21,23-28H2,(H,47,55)(H,49,54,56)	JTVVMXJVTIJQEP-UHFFFAOYSA-N	97117	(R)-N-((S)-2,6-dioxopiperidin-3-yl)-3- (((S)-8-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-1-oxa-8- azaspiro[4.5]decan-3-yl)methyl)- 1,2,3,4,4a,5-hexahydropyrazino[1,2- d]pyrido[2,3-b][1,4]oxazine-8- carboxamide::US20260000676, Compound A147	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97117	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97117&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			2415722	164038361							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130828	COc1cc(N2CCC(CN3CCC(c4ccc(N[C@@H]5CCC(=O)NC5=O)cc4)CC3)CC2)ccc1[C@@H]1c2ccc(O)cc2OC[C@@H]1c1ccccc1	InChI=1S/C44H50N4O5/c1-52-40-25-34(11-13-36(40)43-37-14-12-35(49)26-41(37)53-28-38(43)32-5-3-2-4-6-32)48-23-17-29(18-24-48)27-47-21-19-31(20-22-47)30-7-9-33(10-8-30)45-39-15-16-42(50)46-44(39)51/h2-14,25-26,29,31,38-39,43,45,49H,15-24,27-28H2,1H3,(H,46,50,51)	OMYSZRUHIMRJIW-UHFFFAOYSA-N	97120	(R)-3-((4-(1-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperidin-4- yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A150	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97120	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97120&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			2559619	164038364							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130829	O=C1CC[C@@H](N2Cc3cc4c(cc3C2=O)OCC42CCN(CC3CCC4(CC3)CN(c3ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc3)C4)CC2)C(=O)N1	InChI=1S/C49H52N4O6/c54-36-10-11-37-42(23-36)58-27-39(32-4-2-1-3-5-32)45(37)33-6-8-35(9-7-33)52-28-48(29-52)16-14-31(15-17-48)25-51-20-18-49(19-21-51)30-59-43-24-38-34(22-40(43)49)26-53(47(38)57)41-12-13-44(55)50-46(41)56/h1-11,22-24,31,39,41,45,54H,12-21,25-30H2,(H,50,55,56)	CMWAKGDTWQNPJP-UHFFFAOYSA-N	97123	(R)-3-(1'-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-7-oxo- 5,7-dihydro-2H,6H-spiro[furo[2,3- f]isoindole-3,4'-piperidin]-6-yl)piperidine- 2,6-dione::US20260000676, Compound A153	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97123	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97123&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			793865	164038367							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
130830	O=C1CC[C@@H](N2Cc3c(ccc4c3OCC43CCN(CC4CCC5(CC4)CN(c4ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc4)C5)CC3)C2=O)C(=O)N1	InChI=1S/C49H52N4O6/c54-35-10-11-37-42(24-35)58-27-39(32-4-2-1-3-5-32)44(37)33-6-8-34(9-7-33)52-28-48(29-52)18-16-31(17-19-48)25-51-22-20-49(21-23-51)30-59-45-38-26-53(41-14-15-43(55)50-46(41)56)47(57)36(38)12-13-40(45)49/h1-13,24,31,39,41,44,54H,14-23,25-30H2,(H,50,55,56)	BPZMDXPICADHQA-UHFFFAOYSA-N	97124	(R)-3-(1'-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-6-oxo- 6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A154	Steroid hormone receptor ERR1 LBD	Homo sapiens		<5.00							US Patent		10.7270/Q22F7T7F			US20260000676	Xu, G; Acharyya, RK; Rej, R; Chen, Z; Hu, B; Lu, J; Wang, S	1/1/2026	5/13/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97124	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000411&target=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97124&enzyme=Steroid+hormone+receptor+ERR1+LBD&column=ki&startPg=0&Increment=50&submit=Search			646459	164038368							1	MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD	1XB7,3K6P,7E2E	Steroid hormone receptor ERR1	ERR1_HUMAN	P11474	Q14514