BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
136046	C[C@@H]8Cc1c([nH]c2ccccc12)[C@@H](c7cnc(N6CCC(N5CCN(c4ccc(NC3CCC(=O)NC3=O)cc4F)CC5)CC6)nc7)N8CC(F)F	InChI=1S/C38H44F3N9O2/c1-23-18-28-27-4-2-3-5-30(27)45-35(28)36(50(23)22-33(40)41)24-20-42-38(43-21-24)49-12-10-26(11-13-49)47-14-16-48(17-15-47)32-8-6-25(19-29(32)39)44-31-7-9-34(51)46-37(31)52/h2-6,8,19-21,23,26,31,33,36,44-45H,7,9-18,22H2,1H3,(H,46,51,52)	VKXBICAYRASHLV-UHFFFAOYSA-N	193080	3-((4-(4-(1-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)piperidin-4-yl)piperazin-1-yl)-3- fluorophenyl)amino)piperidine-2,6-dione::US20260007681, Compound A1	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=193080	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=193080&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			73441911	317230480							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136047	C[C@@H]8Cc1c([nH]c2ccccc12)[C@@H](c7cnc(N6CCC(N5CCN(c4ccc(NC3CCC(=O)NC3=O)cc4F)CC5)CC6)nc7)N8CC(C)(C)F	InChI=1S/C40H49F2N9O2/c1-25-20-30-29-6-4-5-7-32(29)46-36(30)37(51(25)24-40(2,3)42)26-22-43-39(44-23-26)50-14-12-28(13-15-50)48-16-18-49(19-17-48)34-10-8-27(21-31(34)41)45-33-9-11-35(52)47-38(33)53/h4-8,10,21-23,25,28,33,37,45-46H,9,11-20,24H2,1-3H3,(H,47,52,53)	ZTWCGKQCSGYWQV-UHFFFAOYSA-N	193082	3-((3-fluoro-4-(4-(1-(5-((1R,3R)-2-(2- fluoro-2-methylpropyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1- yl)pyrimidin-2-yl)piperidin-4-yl)piperazin- 1-yl)phenyl)amino)piperidine-2,6-dione::US20260007681, Compound A2	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=193082	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=193082&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			73441865	317230482							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136048	C[C@@H]8Cc1c([nH]c2ccccc12)[C@@H](c7cnc(N6CCC(N5CCC(c4ccc(NC3CCC(=O)NC3=O)cc4F)CC5)CC6)nc7)N8CC(F)F	InChI=1S/C39H45F3N8O2/c1-23-18-30-29-4-2-3-5-32(29)46-36(30)37(50(23)22-34(41)42)25-20-43-39(44-21-25)49-16-12-27(13-17-49)48-14-10-24(11-15-48)28-7-6-26(19-31(28)40)45-33-8-9-35(51)47-38(33)52/h2-7,19-21,23-24,27,33-34,37,45-46H,8-18,22H2,1H3,(H,47,51,52)	MHLAGDGKSQVFQO-UHFFFAOYSA-N	193083	3-((4-(1'-(5-((1R,3R)-2-(2,2-difluoroethyl)- 3-methyl-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)pyrimidin-2-yl)- [1,4'-bipiperidin]-4-yl)-3- fluorophenyl)amino)piperidine-2,6-dione::US20260007681, Compound A3	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=193083	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=193083&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			90073811	317230483							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136049	C[C@@H]%11Cc1c([nH]c2ccccc12)[C@@H](c%10cnc(N9C[C@@H]8[C@@H](CN7CCN6c5cc4CN(C3CCC(=O)NC3=O)C(=O)c4cc5OC[C@@H]6C7)[C@@H]8C9)nc%10)N%11CC(F)F	InChI=1S/C42H45F2N9O4/c1-22-10-28-26-4-2-3-5-32(26)47-38(28)39(52(22)20-36(43)44)24-13-45-42(46-14-24)50-18-30-29(31(30)19-50)17-49-8-9-51-25(16-49)21-57-35-12-27-23(11-34(35)51)15-53(41(27)56)33-6-7-37(54)48-40(33)55/h2-5,11-14,22,25,29-31,33,36,39,47H,6-10,15-21H2,1H3,(H,48,54,55)	XWLHEKLYOZIHSW-UHFFFAOYSA-N	193084	(S)-3-((S)-3-(((1R,5S,6S)-3-(5-((1R,3R)-2- (2,2-difluoroethyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1- yl)pyrimidin-2-yl)-3- azabicyclo[3.1.0]hexan-6-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A4	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=193084	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=193084&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			121596859	317230484							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136050	C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N8CCC(CN7CCN6c5ccc4C(=O)N(C3CCC(=O)NC3=O)Cc4c5OC[C@@H]6C7)CC8)nc9)N%10CC(F)F	InChI=1S/C42H47F2N9O4/c1-24-16-30-28-4-2-3-5-32(28)47-37(30)38(52(24)22-35(43)44)26-17-45-42(46-18-26)50-12-10-25(11-13-50)19-49-14-15-51-27(20-49)23-57-39-31-21-53(34-8-9-36(54)48-40(34)55)41(56)29(31)6-7-33(39)51/h2-7,17-18,24-25,27,34-35,38,47H,8-16,19-23H2,1H3,(H,48,54,55)	HIPYCPSIFQICFX-UHFFFAOYSA-N	193085	3-((S)-7-((1-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A5	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=193085	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=193085&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			121596860	317230485							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136051	C[C@@H]%11Cc1c([nH]c2ccccc12)[C@@H](c%10cnc(N3CCC9(CC3)CC(CN8CCN7c6ccc5C(=O)N(C4CCC(=O)NC4=O)Cc5c6OC[C@@H]7C8)C9)nc%10)N%11CC(F)F	InChI=1S/C45H51F2N9O4/c1-26-16-32-30-4-2-3-5-34(30)50-39(32)40(55(26)24-37(46)47)28-19-48-44(49-20-28)53-12-10-45(11-13-53)17-27(18-45)21-52-14-15-54-29(22-52)25-60-41-33-23-56(36-8-9-38(57)51-42(36)58)43(59)31(33)6-7-35(41)54/h2-7,19-20,26-27,29,36-37,40,50H,8-18,21-25H2,1H3,(H,51,57,58)	CJGXXJJNOAUSEF-UHFFFAOYSA-N	206000	3-((S)-7-((7-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-7-azaspiro[3.5]nonan-2-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A6	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206000	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206000&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67958363	321901569							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136052	COc7ccc(C(=O)N6CCC(CN5CCN(c4ncc([C@@H]3c2[nH]c1ccccc1c2C[C@@H](C)N3CC(F)F)cn4)CC5)CC6)cc7N8CCC(=O)NC8=O	InChI=1S/C40H47F2N9O4/c1-25-19-30-29-5-3-4-6-31(29)45-36(30)37(51(25)24-34(41)42)28-21-43-39(44-22-28)49-17-15-47(16-18-49)23-26-9-12-48(13-10-26)38(53)27-7-8-33(55-2)32(20-27)50-14-11-35(52)46-40(50)54/h3-8,20-22,25-26,34,37,45H,9-19,23-24H2,1-2H3,(H,46,52,54)	OMPNJRGJQFFFIQ-UHFFFAOYSA-N	206001	1-(5-(4-((4-(5-((1R,3R)-2- (2,2-difluoroethyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol- 1-yl)pyrimidin-2-yl)piperazin-1- yl)methyl)piperidine-1-carbonyl)- 2-methoxyphenyl) dihydropyrimidine-2,4(1H,3H)-dione::US20260007681, Compound A7	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206001	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206001&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			57387630	321901570							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136053	CS(=O)(=O)N3CCc1c([nH]c2ccccc12)C3c%10c(F)cc(N9CCC8(CCN(C(=O)CN7Cc6cc5CN(C4CCC(=O)NC4=O)C(=O)c5cc6C7)CC8)CC9)cc%10F	InChI=1S/C44H47F2N7O6S/c1-60(58,59)53-13-8-31-30-4-2-3-5-35(30)47-40(31)41(53)39-33(45)20-29(21-34(39)46)50-14-9-44(10-15-50)11-16-51(17-12-44)38(55)25-49-22-26-18-28-24-52(36-6-7-37(54)48-42(36)56)43(57)32(28)19-27(26)23-49/h2-5,18-21,36,41,47H,6-17,22-25H2,1H3,(H,48,54,56)	LWPPWLCUZBKBGQ-UHFFFAOYSA-N	206002	6-(2-(9-(3,5-difluoro-4-((R)-2- (methylsulfonyl)-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol- 1-yl)phenyl)-3,9- diazaspiro[5.5]undecan-3-yl)-2- oxoethyl)-2-(2,6-dioxopiperidin-3- yl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260007681, Compound A8	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206002	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206002&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			57387629	321901571							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136054	C[C@@H]%11Cc1c([nH]c2ccccc12)[C@@H](c%10cnc(N9CCC8(CCC(CN7CCN6c5cc4CN(C3CCC(=O)NC3=O)C(=O)c4cc5OC[C@@H]6C7)CC8)CC9)nc%10)N%11CC(C)(C)F	InChI=1S/C49H60FN9O4/c1-30-20-37-35-6-4-5-7-38(35)53-43(37)44(59(30)29-48(2,3)50)33-23-51-47(52-24-33)56-16-14-49(15-17-56)12-10-31(11-13-49)25-55-18-19-57-34(27-55)28-63-41-22-36-32(21-40(41)57)26-58(46(36)62)39-8-9-42(60)54-45(39)61/h4-7,21-24,30-31,34,39,44,53H,8-20,25-29H2,1-3H3,(H,54,60,61)	NRTUNPNKLRJYEH-UHFFFAOYSA-N	206003	(S)-3-((S)-3-((3-(5-((1R,3R)-2-(2-fluoro-2- methylpropyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1- yl)pyrimidin-2-yl)-3-azaspiro[5.5] undecan-9-yl)methyl)-8-oxo-1,2,3,4, 4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A9	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206003	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206003&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			57387632	321901572							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136055	COc7cc(N6CCC(CN5CCN4c3cc2CN(C1CCC(=O)NC1=O)C(=O)c2cc3OC[C@@H]4C5)CC6)ccc7C%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-17-34-31-5-3-4-6-35(31)48-42(34)43(53(26)24-40(46)47)32-8-7-29(19-38(32)58-2)51-13-11-27(12-14-51)21-50-15-16-52-30(23-50)25-59-39-20-33-28(18-37(39)52)22-54(45(33)57)36-9-10-41(55)49-44(36)56/h3-8,18-20,26-27,30,36,40,43,48H,9-17,21-25H2,1-2H3,(H,49,55,56)	ZHTPIQFRAPUAAQ-UHFFFAOYSA-N	206004	(S)-3-((S)-7-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A10	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206004	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206004&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			57387631	321901573							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136056	C[C@@H]%11Cc1c([nH]c2ccccc12)C(c%10cnc(N3CCC9(CC3)CC(CN8CCN7c6cc5CN(C4CCC(=O)NC4=O)C(=O)c5cc6OC[C@@H]7C8)C9)nc%10)N%11CC(F)F	InChI=1S/C45H51F2N9O4/c1-26-14-33-31-4-2-3-5-34(31)50-40(33)41(55(26)24-38(46)47)29-19-48-44(49-20-29)53-10-8-45(9-11-53)17-27(18-45)21-52-12-13-54-30(23-52)25-60-37-16-32-28(15-36(37)54)22-56(43(32)59)35-6-7-39(57)51-42(35)58/h2-5,15-16,19-20,26-27,30,35,38,41,50H,6-14,17-18,21-25H2,1H3,(H,51,57,58)	VXOVPXRYBIBHEU-UHFFFAOYSA-N	206005	(S)-3-((S)-3-((7-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyridin-2-yl)- 7-azaspiro[3.5]nonan-2-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A11	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206005	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206005&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			57387857	321901574							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136057	COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@H]1CCC(=O)NC1=O)Cc2c3OC[C@@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-19-33-30-5-3-4-6-35(30)48-41(33)42(53(26)24-39(46)47)32-8-7-28(20-38(32)58-2)51-15-13-27(14-16-51)21-50-17-18-52-29(22-50)25-59-43-34-23-54(37-11-12-40(55)49-44(37)56)45(57)31(34)9-10-36(43)52/h3-10,20,26-27,29,37,39,42,48H,11-19,21-25H2,1-2H3,(H,49,55,56)	WJHSKRHFCXEXIR-UHFFFAOYSA-N	206006	(S)-3-((S)-7-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A12	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206006	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206006&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			57387856	321901575							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136058	C[C@@H]%11Cc1c([nH]c2ccccc12)[C@@H](c%10cnc(N9C[C@H]8[C@@H](CN7CCN6c5cc4CN([C@H]3CCC(=O)NC3=O)C(=O)c4cc5OC[C@@H]6C7)[C@H]8C9)nc%10)N%11CC(C)(C)F	InChI=1S/C44H50FN9O4/c1-24-12-30-28-6-4-5-7-34(28)48-39(30)40(54(24)23-44(2,3)45)26-15-46-43(47-16-26)51-20-32-31(33(32)21-51)19-50-10-11-52-27(18-50)22-58-37-14-29-25(13-36(37)52)17-53(42(29)57)35-8-9-38(55)49-41(35)56/h4-7,13-16,24,27,31-33,35,40,48H,8-12,17-23H2,1-3H3,(H,49,55,56)	BIFISHBUJGWIFX-UHFFFAOYSA-N	206007	(S)-3-((S)-3-(((1R,5S,6R)-3-(5-((1R,3R)- 2-(2-fluoro-2-methylpropyl)-3-methyl- 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol- 1-yl)pyrimidin-2-yl)-3- azabicyclo[3.1.0]hexan-6-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A13	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206007	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206007&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			57387858	321901576							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136059	C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N8CC[C@@H](CN7CCN6c5ccc4C(=O)N(C3CCC(=O)NC3=O)Cc4c5OC[C@@H]6C7)C8)nc9)N%10CC(F)F	InChI=1S/C41H45F2N9O4/c1-23-14-29-27-4-2-3-5-31(27)46-36(29)37(51(23)21-34(42)43)25-15-44-41(45-16-25)49-11-10-24(18-49)17-48-12-13-50-26(19-48)22-56-38-30-20-52(33-8-9-35(53)47-39(33)54)40(55)28(30)6-7-32(38)50/h2-7,15-16,23-24,26,33-34,37,46H,8-14,17-22H2,1H3,(H,47,53,54)	KATCQWWFAUCYKO-UHFFFAOYSA-N	206008	3-((S)-7-(((S)-1-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)pyrrolidin-3-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A14	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206008	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206008&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968116	321901577							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136060	Cc9nn(C1CCC(=O)NC1=O)c%10ccc(N8CCN(CC7CC6(CCN(c5ncc([C@@H]4c3[nH]c2ccccc2c3C[C@@H](C)N4CC(C)(C)F)cn5)CC6)C7)CC8)cc9%10	InChI=1S/C46H57FN10O2/c1-29-21-36-34-7-5-6-8-37(34)50-41(36)42(56(29)28-45(3,4)47)32-25-48-44(49-26-32)55-15-13-46(14-16-55)23-31(24-46)27-53-17-19-54(20-18-53)33-9-10-38-35(22-33)30(2)52-57(38)39-11-12-40(58)51-43(39)59/h5-10,22,25-26,29,31,39,42,50H,11-21,23-24,27-28H2,1-4H3,(H,51,58,59)	KFHQKFNJAIXWFY-UHFFFAOYSA-N	206009	3-(5-(4-((7-(5-((1R,3R)-2-(2-fluoro-2- methylpropyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1- yl)pyrimidin-2-yl)-7-azaspiro[3.5]nonan- 2-yl)methyl)piperazin-1-yl)-3-methyl-1H- indazol-1-yl)piperidine-2,6-dione::US20260007681, Compound A15	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206009	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206009&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968114	321901578							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136061	C[C@@H]9Cc1c([nH]c2ccccc12)[C@@H](c8cnc(N3CCC7(CC3)CC(CN6CCN(c5ccc(NC4CCC(=O)NC4=O)cc5F)CC6)C7)nc8)N9CC(F)F	InChI=1S/C42H50F3N9O2/c1-26-18-31-30-4-2-3-5-33(30)49-38(31)39(54(26)25-36(44)45)28-22-46-41(47-23-28)53-12-10-42(11-13-53)20-27(21-42)24-51-14-16-52(17-15-51)35-8-6-29(19-32(35)43)48-34-7-9-37(55)50-40(34)56/h2-6,8,19,22-23,26-27,34,36,39,48-49H,7,9-18,20-21,24-25H2,1H3,(H,50,55,56)	XYQYHNIPYWHJGY-UHFFFAOYSA-N	206010	3-((4-(4-((7-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1-yl) pyrimidin-2-yl)-7-azaspiro[3.5]nonan- 2-yl)methyl)piperazin-1-yl)-3- fluorophenyl)amino)piperidine-2,6-dione::US20260007681, Compound A16	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206010	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206010&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968074	321901579							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136062	CS(=O)(=O)N3CCc1c([nH]c2ccccc12)[C@H]3c%10c(F)cc(N9CCC(CN8CCN7c6cc5CN([C@H]4CCC(=O)NC4=O)C(=O)c5cc6OC[C@@H]7C8)CC9)cc%10F	InChI=1S/C42H45F2N7O6S/c1-58(55,56)51-13-10-29-28-4-2-3-5-33(28)45-39(29)40(51)38-31(43)17-26(18-32(38)44)48-11-8-24(9-12-48)20-47-14-15-49-27(22-47)23-57-36-19-30-25(16-35(36)49)21-50(42(30)54)34-6-7-37(52)46-41(34)53/h2-5,16-19,24,27,34,40,45H,6-15,20-23H2,1H3,(H,46,52,53)	MACVXTSHPDAXKN-UHFFFAOYSA-N	206011	(S)-3-((S)-3-((1-(3,5-difluoro-4-((R)-2- (methylsulfonyl)-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)phenyl)piperidin- 4-yl)methyl)-8-oxo-1,2,3,4,4a,5,8,10- octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A17	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206011	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206011&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968112	321901580							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136063	C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(O[C@@H]8C[C@@H](C(=O)N7CCC(N6Cc5cc4c(=O)n(C3CCC(=O)NC3=O)c(=O)c4cc5C6)CC7)C8)nc9)N%10CC(F)F	InChI=1S/C43H44F2N8O6/c1-22-12-30-29-4-2-3-5-33(29)48-37(30)38(52(22)21-35(44)45)26-17-46-43(47-18-26)59-28-13-23(14-28)40(56)50-10-8-27(9-11-50)51-19-24-15-31-32(16-25(24)20-51)42(58)53(41(31)57)34-6-7-36(54)49-39(34)55/h2-5,15-18,22-23,27-28,34-35,38,48H,6-14,19-21H2,1H3,(H,49,54,55)	FHAJPMJPKQQHFW-UHFFFAOYSA-N	206012	6-(1-((1R,3r)-3-((5-((1R,3R)-2- (2,2-difluoroethyl)-3-methyl- 2,3,4,9-tetrahydro-1H-pyrido[3,4- b]indol-1-yl)pyrimidin-2- yl)oxy)cyclobutane-1- carbonyl)piperidin-4-yl)-2-(2,6- dioxopiperidin-3-yl)-6,7- dihydropyrrolo[3,4-f]isoindole- 1,3(2H,5H)-dione::US20260007681, Compound A18	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206012	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206012&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968108	321901581							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136064	COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@H]1CCC(=O)NC1=O)Cc2c3OC[C@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-19-33-30-5-3-4-6-35(30)48-41(33)42(53(26)24-39(46)47)32-8-7-28(20-38(32)58-2)51-15-13-27(14-16-51)21-50-17-18-52-29(22-50)25-59-43-34-23-54(37-11-12-40(55)49-44(37)56)45(57)31(34)9-10-36(43)52/h3-10,20,26-27,29,37,39,42,48H,11-19,21-25H2,1-2H3,(H,49,55,56)	WJHSKRHFCXEXIR-UHFFFAOYSA-N	206013	(S)-3-((R)-7-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- c]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A19	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206013	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206013&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			57387134	321901582							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136065	CS(=O)(=O)N3CCc1c([nH]c2ccccc12)[C@@H]3c%10c(F)cc(N9CCC8(CCN(C(=O)CN7Cc6cc5c(=O)n(C4CCC(=O)NC4=O)c(=O)c5cc6C7)CC8)CC9)cc%10F	InChI=1S/C44H45F2N7O7S/c1-61(59,60)52-13-8-29-28-4-2-3-5-34(28)47-39(29)40(52)38-32(45)20-27(21-33(38)46)50-14-9-44(10-15-50)11-16-51(17-12-44)37(55)24-49-22-25-18-30-31(19-26(25)23-49)43(58)53(42(30)57)35-6-7-36(54)48-41(35)56/h2-5,18-21,35,40,47H,6-17,22-24H2,1H3,(H,48,54,56)	HMZUJNRCPPDGMM-UHFFFAOYSA-N	206014	6-(2-(9-(3,5-difluoro-4-((S)-2- (methylsulfonyl)-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol- 1-yl)phenyl)-3,9- diazaspiro[5.5]undecan-3-yl)-2- oxoethyl)-2-(2,6-dioxopiperidin-3- yl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260007681, Compound A20	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206014&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			57387387	321901583							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136066	CS(=O)(=O)N3CCc1c([nH]c2ccccc12)[C@H]3c%10c(F)cc(N9CCC8(CCN(C(=O)CN7Cc6cc5c(=O)n(C4CCC(=O)NC4=O)c(=O)c5cc6C7)CC8)CC9)cc%10F	InChI=1S/C44H45F2N7O7S/c1-61(59,60)52-13-8-29-28-4-2-3-5-34(28)47-39(29)40(52)38-32(45)20-27(21-33(38)46)50-14-9-44(10-15-50)11-16-51(17-12-44)37(55)24-49-22-25-18-30-31(19-26(25)23-49)43(58)53(42(30)57)35-6-7-36(54)48-41(35)56/h2-5,18-21,35,40,47H,6-17,22-24H2,1H3,(H,48,54,56)	HMZUJNRCPPDGMM-UHFFFAOYSA-N	206015	6-(2-(9-(3,5-difluoro-4-((R)-2- (methylsulfonyl)-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol- 1-yl)phenyl)-3,9- diazaspiro[5.5]undecan-3-yl)-2- oxoethyl)-2-(2,6-dioxopiperidin-3- yl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260007681, Compound A21	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206015	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206015&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968107	321901584							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136207	C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N8CCO[C@H](CN7CCN6c5cc4CN(C3CCC(=O)NC3=O)C(=O)c4cc5OC[C@@H]6C7)C8)nc9)N%10CC(C)(C)F	InChI=1S/C43H50FN9O5/c1-25-14-32-30-6-4-5-7-33(30)47-38(32)39(53(25)24-43(2,3)44)27-17-45-42(46-18-27)50-12-13-57-29(22-50)21-49-10-11-51-28(20-49)23-58-36-16-31-26(15-35(36)51)19-52(41(31)56)34-8-9-37(54)48-40(34)55/h4-7,15-18,25,28-29,34,39,47H,8-14,19-24H2,1-3H3,(H,48,54,55)	WRXACWYBFQONAH-UHFFFAOYSA-N	206016	3-((S)-3-(((R)-4-(5- ((1R,3R)-2-(2-fluoro-2- methylpropyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1- yl)pyrimidin-2-yl)morpholin-2-yl) methyl)-8-oxo-1,2,3,4,4a,5,8,10- octahydro-9H-pyrazino[1',2':4,5][1,4] oxazino[2,3-f]isoindol-9-yl)piperidine- 2,6-dione::US20260007681, Compound A22	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206016	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206016&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968110	321901585							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136208	C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9ccc(N8CCC(CN7CCN6c5ccc4C(=O)N([C@H]3CCC(=O)NC3=O)Cc4c5OC[C@@H]6C7)CC8)nc9)N%10CC(F)F	InChI=1S/C43H48F2N8O4/c1-25-18-31-29-4-2-3-5-33(29)47-39(31)40(52(25)23-36(44)45)27-6-10-37(46-19-27)50-14-12-26(13-15-50)20-49-16-17-51-28(21-49)24-57-41-32-22-53(35-9-11-38(54)48-42(35)55)43(56)30(32)7-8-34(41)51/h2-8,10,19,25-26,28,35-36,40,47H,9,11-18,20-24H2,1H3,(H,48,54,55)	VIVOSFZQNRSSSP-UHFFFAOYSA-N	206017	(S)-3-((S)-7-((1-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyridin-2- yl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A23	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206017	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206017&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968111	321901586							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136209	C[C@@H]%11Cc1c([nH]c2ccccc12)[C@@H](c%10ccc(N3CCC9(CC3)CC(CN8CCN7c6ccc5C(=O)N([C@H]4CCC(=O)NC4=O)Cc5c6OC[C@@H]7C8)C9)nc%10)N%11CC(F)F	InChI=1S/C46H52F2N8O4/c1-27-18-33-31-4-2-3-5-35(31)50-41(33)42(55(27)25-38(47)48)29-6-10-39(49-21-29)53-14-12-46(13-15-53)19-28(20-46)22-52-16-17-54-30(23-52)26-60-43-34-24-56(37-9-11-40(57)51-44(37)58)45(59)32(34)7-8-36(43)54/h2-8,10,21,27-28,30,37-38,42,50H,9,11-20,22-26H2,1H3,(H,51,57,58)	XEFLIBOIERQNRA-UHFFFAOYSA-N	206018	(S)-3-((S)-7-((7-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyridin-2-yl)- 7-azaspiro[3.5]nonan-2-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A24	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206018	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206018&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968113	321901587							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136210	C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc([C@@H]8CC[C@@H](C(=O)N7CCC(N6Cc5cc4CN(C3CCC(=O)NC3=O)C(=O)c4cc5C6)CC7)CC8)nc9)N%10CC(F)F	InChI=1S/C45H50F2N8O4/c1-25-16-35-33-4-2-3-5-36(33)50-40(35)41(54(25)24-38(46)47)31-19-48-42(49-20-31)26-6-8-27(9-7-26)44(58)52-14-12-32(13-15-52)53-21-28-17-30-23-55(37-10-11-39(56)51-43(37)57)45(59)34(30)18-29(28)22-53/h2-5,17-20,25-27,32,37-38,41,50H,6-16,21-24H2,1H3,(H,51,56,57)	QEDOMBSYBFJQCW-UHFFFAOYSA-N	206019	3-(6-(1-((1R,4r)-4-(5-((1R,3R)-2- (2,2-difluoroethyl)-3-methyl- 2,3,4,9-tetrahydro-1H-pyrido[3,4- b]indol-1-yl)pyrimidin-2- yl)cyclohexane-1- carbonyl)piperidin-4-yl)-1-oxo- 3,5,6,7-tetrahydropyrrolo[3,4- f]isoindol-2(1H)-yl)piperidine-2,6- dione::US20260007681, Compound A25	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206019	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206019&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			57387389	321901588							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136211	C[C@@H]%11Cc1c([nH]c2ccccc12)[C@@H](c%10cnc(N3CCC9(CC3)CC(CN4CCC8(CC4)COc7cc6C(=O)N(C5CCC(=O)NC5=O)Cc6cc78)C9)nc%10)N%11CCF	InChI=1S/C46H53FN8O4/c1-28-18-34-32-4-2-3-5-36(32)50-40(34)41(54(28)17-12-47)31-23-48-44(49-24-31)53-15-8-45(9-16-53)21-29(22-45)25-52-13-10-46(11-14-52)27-59-38-20-33-30(19-35(38)46)26-55(43(33)58)37-6-7-39(56)51-42(37)57/h2-5,19-20,23-24,28-29,37,41,50H,6-18,21-22,25-27H2,1H3,(H,51,56,57)	VGDIUYRUDQZFIG-UHFFFAOYSA-N	206020	3-(1'-((7-(5-((1R,3R)-2-(2,2-difluoroethyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1-yl) pyrimidin-2-yl)-7-azaspiro[3.5]nonan- 2-yl)methyl)-7-oxo-5,7-dihydro-2H,6H- spiro[furo[2,3-f]isoindole-3,4'-piperidin]- 6-yl)piperidine-2,6-dione::US20260007681, Compound A26	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206020	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206020&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968115	321901589							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136212	COc7cc(N6CCC5(CCN(C(=O)CN4Cc3cc2c(=O)n(C1CCC(=O)NC1=O)c(=O)c2cc3C4)CC5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C47H51F2N7O6/c1-27-19-33-31-5-3-4-6-36(31)50-42(33)43(55(27)25-39(48)49)32-8-7-30(22-38(32)62-2)53-15-11-47(12-16-53)13-17-54(18-14-47)41(58)26-52-23-28-20-34-35(21-29(28)24-52)46(61)56(45(34)60)37-9-10-40(57)51-44(37)59/h3-8,20-22,27,37,39,43,50H,9-19,23-26H2,1-2H3,(H,51,57,59)	CVBVXFWOFNDQRT-UHFFFAOYSA-N	206021	6-(2-(9-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol- 1-yl)-3-methoxyphenyl)-3,9- diazaspiro[5.5]undecan-3-yl)-2- oxoethyl)-2-(2,6-dioxopiperidin-3- yl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260007681, Compound A27	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206021&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968119	321901590							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136213	COc7cc(N6CCC(CN5CCN4c3cc2CN([C@H]1CCC(=O)NC1=O)C(=O)c2cc3OC[C@@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-17-34-31-5-3-4-6-35(31)48-42(34)43(53(26)24-40(46)47)32-8-7-29(19-38(32)58-2)51-13-11-27(12-14-51)21-50-15-16-52-30(23-50)25-59-39-20-33-28(18-37(39)52)22-54(45(33)57)36-9-10-41(55)49-44(36)56/h3-8,18-20,26-27,30,36,40,43,48H,9-17,21-25H2,1-2H3,(H,49,55,56)	ZHTPIQFRAPUAAQ-UHFFFAOYSA-N	206022	(S)-3-((S)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)- 8-oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A28	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206022	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206022&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968121	321901591							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136214	COc7cc(N6CCC(CN5CCN4c3cc2CN([C@H]1CCC(=O)NC1=O)C(=O)c2cc3OC[C@@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-17-34-31-5-3-4-6-35(31)48-42(34)43(53(26)24-40(46)47)32-8-7-29(19-38(32)58-2)51-13-11-27(12-14-51)21-50-15-16-52-30(23-50)25-59-39-20-33-28(18-37(39)52)22-54(45(33)57)36-9-10-41(55)49-44(36)56/h3-8,18-20,26-27,30,36,40,43,48H,9-17,21-25H2,1-2H3,(H,49,55,56)	ZHTPIQFRAPUAAQ-UHFFFAOYSA-N	206023	(S)-3-((S)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A29	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206023	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206023&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968126	321901592							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136215	COc6cc(N5CCC(CN4CCN3c2cc(F)c(C(=O)N[C@H]1CCC(=O)NC1=O)cc2OC[C@@H]3C4)CC5)ccc6[C@@H]9c8[nH]c7ccccc7c8C[C@@H](C)N9CC(F)F	InChI=1S/C44H50F3N7O5/c1-25-17-31-29-5-3-4-6-34(29)48-41(31)42(54(25)23-39(46)47)30-8-7-27(18-37(30)58-2)52-13-11-26(12-14-52)21-51-15-16-53-28(22-51)24-59-38-19-32(33(45)20-36(38)53)43(56)49-35-9-10-40(55)50-44(35)57/h3-8,18-20,25-26,28,35,39,42,48H,9-17,21-24H2,1-2H3,(H,49,56)(H,50,55,57)	XYUGKDSHQAEBLF-UHFFFAOYSA-N	206024	(S)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)- N-((S)-2,6-dioxopiperidin-3-yl)-9-fluoro- 1,2,3,4,4a,5- hexahydrobenzo[b]pyrazino[1,2- d][1,4]oxazine-8-carboxamide::US20260007681, Compound A30	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206024	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206024&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968081	321901593							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136216	COc5cc(N4CCC(CN3CCN(c2ccc(NC1CCC(=O)NC1=O)cc2F)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F	InChI=1S/C42H50F3N7O3/c1-26-21-32-30-5-3-4-6-34(30)47-40(32)41(52(26)25-38(44)45)31-9-8-29(23-37(31)55-2)50-15-13-27(14-16-50)24-49-17-19-51(20-18-49)36-11-7-28(22-33(36)43)46-35-10-12-39(53)48-42(35)54/h3-9,11,22-23,26-27,35,38,41,46-47H,10,12-21,24-25H2,1-2H3,(H,48,53,54)	HPHUKWYNBMSJEN-UHFFFAOYSA-N	206025	3-((4-(4-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)-3- fluorophenyl)amino)piperidine-2,6-dione::US20260007681, Compound A31	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206025	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206025&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968075	321901594							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136217	C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N3CCC8(CC3)CC(CN7CCC(c4ccc5c(c4)n(C)c(=O)n5C6CCC(=O)NC6=O)CC7)C8)nc9)N%10CC(F)F	InChI=1S/C45H53F2N9O3/c1-27-19-33-32-5-3-4-6-34(32)50-40(33)41(55(27)26-38(46)47)31-23-48-43(49-24-31)54-17-13-45(14-18-54)21-28(22-45)25-53-15-11-29(12-16-53)30-7-8-35-37(20-30)52(2)44(59)56(35)36-9-10-39(57)51-42(36)58/h3-8,20,23-24,27-29,36,38,41,50H,9-19,21-22,25-26H2,1-2H3,(H,51,57,58)	KIRYOWGBLGLINP-UHFFFAOYSA-N	206026	3-(5-(1-((7-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-7-azaspiro[3.5]nonan-2- yl)methyl)piperidin-4-yl)-3-methyl-2-oxo- 2,3-dihydro-1H-benzo[d]imidazol-1- yl)piperidine-2,6-dione::US20260007681, Compound A32	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206026	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206026&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968079	321901595							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136218	COc7cc(N6CCC(CN1CCC5(CC1)COc4cc3C(=O)N(C2CCC(=O)NC2=O)Cc3cc45)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C46H52F2N6O5/c1-27-19-34-31-5-3-4-6-36(31)49-42(34)43(53(27)25-40(47)48)32-8-7-30(21-38(32)58-2)52-15-11-28(12-16-52)23-51-17-13-46(14-18-51)26-59-39-22-33-29(20-35(39)46)24-54(45(33)57)37-9-10-41(55)50-44(37)56/h3-8,20-22,27-28,37,40,43,49H,9-19,23-26H2,1-2H3,(H,50,55,56)	JIQQCYWIYSAICS-UHFFFAOYSA-N	206027	3-(1'-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-7- oxo-5,7-dihydro-2H,6H-spiro[furo[2,3- f]isoindole-3,4'-piperidin]-6-yl) piperidine-2,6-dione::US20260007681, Compound A33	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206027&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968082	321901596							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136220	COc5cc(N4CCC(CN3CCC(c2ccc(N[C@H]1CCC(=O)NC1=O)cc2F)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F	InChI=1S/C43H51F3N6O3/c1-26-21-34-32-5-3-4-6-36(32)48-41(34)42(52(26)25-39(45)46)33-10-8-30(23-38(33)55-2)51-19-13-27(14-20-51)24-50-17-15-28(16-18-50)31-9-7-29(22-35(31)44)47-37-11-12-40(53)49-43(37)54/h3-10,22-23,26-28,37,39,42,47-48H,11-21,24-25H2,1-2H3,(H,49,53,54)	HQOQXUHKLUVJIL-UHFFFAOYSA-N	206028	(S)-3-((4-(1-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperidin-4-yl)-3- fluorophenyl)amino)piperidine-2,6- dione::US20260007681, Compound A34	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206028	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206028&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968080	321901597							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136221	COc5cc(N4CCC(CN3CCN(c2ccc(NC1CCC(=O)NC1=O)cc2F)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F	InChI=1S/C42H50F3N7O3/c1-26-21-32-30-5-3-4-6-34(30)47-40(32)41(52(26)25-38(44)45)31-9-8-29(23-37(31)55-2)50-15-13-27(14-16-50)24-49-17-19-51(20-18-49)36-11-7-28(22-33(36)43)46-35-10-12-39(53)48-42(35)54/h3-9,11,22-23,26-27,35,38,41,46-47H,10,12-21,24-25H2,1-2H3,(H,48,53,54)	HPHUKWYNBMSJEN-UHFFFAOYSA-N	206029	3-(5-(1-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperidin-4-yl)-3-methyl-2-oxo- 2,3-dihydro-1H-benzo[d]imidazol-1- yl)piperidine-2,6-dione::US20260007681, Compound A35	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206029	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206029&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968077	321901598							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136222	C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N8CCC(CN3CCC7(CC3)COc6cc5C(=O)N(C4CCC(=O)NC4=O)Cc5cc67)CC8)nc9)N%10CC(F)(F)CO	InChI=1S/C44H50F2N8O5/c1-26-16-32-30-4-2-3-5-34(30)49-38(32)39(54(26)23-44(45,46)24-55)29-19-47-42(48-20-29)52-12-8-27(9-13-52)21-51-14-10-43(11-15-51)25-59-36-18-31-28(17-33(36)43)22-53(41(31)58)35-6-7-37(56)50-40(35)57/h2-5,17-20,26-27,35,39,49,55H,6-16,21-25H2,1H3,(H,50,56,57)	RNFIEXJKUWCZCC-UHFFFAOYSA-N	206030	3-(1'-((1-(5-((1R,3R)-2-(2,2-difluoro-3- hydroxypropyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1- yl)pyrimidin-2-yl)piperidin-4-yl)methyl)- 7-oxo-5,7-dihydro-2H,6H-spiro[furo[2,3- f]isoindole-3,4'-piperidin]-6-yl) piperidine-2,6-dione::US20260007681, Compound A36	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206030	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206030&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968078	321901599							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136223	COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@@H]1CCC(=O)NC1=O)Cc2c3OC[C@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-19-33-30-5-3-4-6-35(30)48-41(33)42(53(26)24-39(46)47)32-8-7-28(20-38(32)58-2)51-15-13-27(14-16-51)21-50-17-18-52-29(22-50)25-59-43-34-23-54(37-11-12-40(55)49-44(37)56)45(57)31(34)9-10-36(43)52/h3-10,20,26-27,29,37,39,42,48H,11-19,21-25H2,1-2H3,(H,49,55,56)	WJHSKRHFCXEXIR-UHFFFAOYSA-N	206031	(R)-3-((R)-7-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A37	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206031&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968076	321901600							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136224	C[C@@H]8Cc1c([nH]c2ccccc12)[C@@H](c7cnc(N6CCN(CC5CCN(c4ccc(N3CCC(=O)NC3=O)cc4)CC5)CC6)nc7)N8CC(F)F	InChI=1S/C38H45F2N9O2/c1-25-20-31-30-4-2-3-5-32(30)43-35(31)36(49(25)24-33(39)40)27-21-41-37(42-22-27)47-18-16-45(17-19-47)23-26-10-13-46(14-11-26)28-6-8-29(9-7-28)48-15-12-34(50)44-38(48)51/h2-9,21-22,25-26,33,36,43H,10-20,23-24H2,1H3,(H,44,50,51)	RABAFWIHYJUOOX-UHFFFAOYSA-N	206032	1-(4-(4-((4-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol- 1-yl)pyrimidin-2-yl)piperazin-1- yl)methyl)piperidin-1- yl)phenyl)dihydropyrimidine- 2,4(1H,3H)-dione::US20260007681, Compound A38	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206032	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206032&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968083	321901601							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136225	COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@H]1CCC(=O)NC1=O)Cc2c3OC[C@H]4C5)CC6)ccc7[C@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-19-33-30-5-3-4-6-35(30)48-41(33)42(53(26)24-39(46)47)32-8-7-28(20-38(32)58-2)51-15-13-27(14-16-51)21-50-17-18-52-29(22-50)25-59-43-34-23-54(37-11-12-40(55)49-44(37)56)45(57)31(34)9-10-36(43)52/h3-10,20,26-27,29,37,39,42,48H,11-19,21-25H2,1-2H3,(H,49,55,56)	WJHSKRHFCXEXIR-UHFFFAOYSA-N	206033	(S)-3-((R)-7-((1-(4-((1S,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A39	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206033	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206033&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			57387133	321901602							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136226	COc5cc(N4CCC(CN3CCC(c2ccc(N[C@H]1CCC(=O)NC1=O)c(F)c2)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F	InChI=1S/C43H51F3N6O3/c1-26-21-33-31-5-3-4-6-35(31)48-41(33)42(52(26)25-39(45)46)32-9-8-30(23-38(32)55-2)51-19-13-27(14-20-51)24-50-17-15-28(16-18-50)29-7-10-36(34(44)22-29)47-37-11-12-40(53)49-43(37)54/h3-10,22-23,26-28,37,39,42,47-48H,11-21,24-25H2,1-2H3,(H,49,53,54)	GYVVNFGCGAREKN-UHFFFAOYSA-N	206034	(S)-3-((4-(1-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperidin-4-yl)-2- fluorophenyl)amino)piperidine-2,6-dione::US20260007681, Compound A40	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206034	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206034&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			57387388	321901603							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136227	COc5cc(N4CCC(CN3CCN(c2ccc(NC1CCC(=O)NC1=O)c(F)c2)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F	InChI=1S/C42H50F3N7O3/c1-26-21-32-30-5-3-4-6-34(30)47-40(32)41(52(26)25-38(44)45)31-9-7-29(23-37(31)55-2)50-15-13-27(14-16-50)24-49-17-19-51(20-18-49)28-8-10-35(33(43)22-28)46-36-11-12-39(53)48-42(36)54/h3-10,22-23,26-27,36,38,41,46-47H,11-21,24-25H2,1-2H3,(H,48,53,54)	AKUMKBYUJBNBSB-UHFFFAOYSA-N	206035	3-((4-(4-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)-2- fluorophenyl)amino)piperidine-2,6-dione::US20260007681, Compound A41	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206035	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206035&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968128	321901604							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136228	COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@@H]1CCC(=O)NC1=O)Cc2c3OC[C@@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-19-33-30-5-3-4-6-35(30)48-41(33)42(53(26)24-39(46)47)32-8-7-28(20-38(32)58-2)51-15-13-27(14-16-51)21-50-17-18-52-29(22-50)25-59-43-34-23-54(37-11-12-40(55)49-44(37)56)45(57)31(34)9-10-36(43)52/h3-10,20,26-27,29,37,39,42,48H,11-19,21-25H2,1-2H3,(H,49,55,56)	WJHSKRHFCXEXIR-UHFFFAOYSA-N	206036	(R)-3-((S)-7-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A42	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206036	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206036&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968129	321901605							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136229	COc5cc(N4CCC(CN3CCN(c2ccc(C(=O)N[C@H]1CCC(=O)NC1=O)nc2)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F	InChI=1S/C42H50F2N8O4/c1-26-21-32-30-5-3-4-6-33(30)46-39(32)40(52(26)25-37(43)44)31-9-7-28(22-36(31)56-2)50-15-13-27(14-16-50)24-49-17-19-51(20-18-49)29-8-10-34(45-23-29)41(54)47-35-11-12-38(53)48-42(35)55/h3-10,22-23,26-27,35,37,40,46H,11-21,24-25H2,1-2H3,(H,47,54)(H,48,53,55)	OYMOSSFRFJBEGC-UHFFFAOYSA-N	206037	5-(4-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-methyl-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((S)-2,6- dioxopiperidin-3-yl)picolinamide::US20260007681, Compound A43	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206037	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206037&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968150	321901606							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136230	COc7cc(N6CCC(CN5CCN4c3cc2CN([C@@H]1CCC(=O)NC1=O)C(=O)c2cc3OC[C@@H]4C5)CC6)ccc7[C@H]%10c9[nH]c8ccccc8c9C[C@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-17-34-31-5-3-4-6-35(31)48-42(34)43(53(26)24-40(46)47)32-8-7-29(19-38(32)58-2)51-13-11-27(12-14-51)21-50-15-16-52-30(23-50)25-59-39-20-33-28(18-37(39)52)22-54(45(33)57)36-9-10-41(55)49-44(36)56/h3-8,18-20,26-27,30,36,40,43,48H,9-17,21-25H2,1-2H3,(H,49,55,56)	ZHTPIQFRAPUAAQ-UHFFFAOYSA-N	206038	(R)-3-((S)-3-((1-(4-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A44	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206038	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206038&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968151	321901607							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136231	COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@H]1CCC(=O)NC1=O)Cc2c3OC[C@@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-19-33-30-5-3-4-6-35(30)48-41(33)42(53(26)24-39(46)47)32-8-7-28(20-38(32)58-2)51-15-13-27(14-16-51)21-50-17-18-52-29(22-50)25-59-43-34-23-54(37-11-12-40(55)49-44(37)56)45(57)31(34)9-10-36(43)52/h3-10,20,26-27,29,37,39,42,48H,11-19,21-25H2,1-2H3,(H,49,55,56)	WJHSKRHFCXEXIR-UHFFFAOYSA-N	206041	(S)-3-((S)-7-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A45	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206041	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206041&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968132	321901608							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136232	COc5cc(N4CCC(CN3CCN(c2ccc(C1CCC(=O)NC1=O)cc2)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F	InChI=1S/C42H50F2N6O3/c1-27-23-35-33-5-3-4-6-36(33)45-40(35)41(50(27)26-38(43)44)34-12-11-31(24-37(34)53-2)48-17-15-28(16-18-48)25-47-19-21-49(22-20-47)30-9-7-29(8-10-30)32-13-14-39(51)46-42(32)52/h3-12,24,27-28,32,38,41,45H,13-23,25-26H2,1-2H3,(H,46,51,52)	JFMHDGSSQOZYFW-UHFFFAOYSA-N	206042	3-(4-(4-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol- 1-yl)-3-methoxyphenyl)piperidin-4- yl)methyl)piperazin-1- yl)phenyl)piperidine-2,6-dione::US20260007681, Compound A46	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206042	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206042&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968137	321901609							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136233	COc7cc(N6CCC(CN5CCN4c3cc2CN([C@@H]1CCC(=O)NC1=O)C(=O)c2cc3OC[C@@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-17-34-31-5-3-4-6-35(31)48-42(34)43(53(26)24-40(46)47)32-8-7-29(19-38(32)58-2)51-13-11-27(12-14-51)21-50-15-16-52-30(23-50)25-59-39-20-33-28(18-37(39)52)22-54(45(33)57)36-9-10-41(55)49-44(36)56/h3-8,18-20,26-27,30,36,40,43,48H,9-17,21-25H2,1-2H3,(H,49,55,56)	ZHTPIQFRAPUAAQ-UHFFFAOYSA-N	206043	US20260007681, Compound A47	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206043	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206043&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968138	321901610							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136234	COc7cc(N6CCC(CN5CCN4c3cc2CN([C@@H]1CCC(=O)NC1=O)C(=O)c2cc3OC[C@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-17-34-31-5-3-4-6-35(31)48-42(34)43(53(26)24-40(46)47)32-8-7-29(19-38(32)58-2)51-13-11-27(12-14-51)21-50-15-16-52-30(23-50)25-59-39-20-33-28(18-37(39)52)22-54(45(33)57)36-9-10-41(55)49-44(36)56/h3-8,18-20,26-27,30,36,40,43,48H,9-17,21-25H2,1-2H3,(H,49,55,56)	ZHTPIQFRAPUAAQ-UHFFFAOYSA-N	206046	(R)-3-((R)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A48	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206046&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968134	321901611							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136235	COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@H]1CCC(=O)NC1=O)Cc2c3OC[C@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(C)(C)F	InChI=1S/C47H56FN7O5/c1-28-21-35-32-7-5-6-8-37(32)49-42(35)43(55(28)27-47(2,3)48)34-10-9-30(22-40(34)59-4)52-17-15-29(16-18-52)23-51-19-20-53-31(24-51)26-60-44-36-25-54(39-13-14-41(56)50-45(39)57)46(58)33(36)11-12-38(44)53/h5-12,22,28-29,31,39,43,49H,13-21,23-27H2,1-4H3,(H,50,56,57)	AEBNLOFIJHRQAU-UHFFFAOYSA-N	206048	(S)-3-((R)-7-((1-(4-((1R,3R)-2-(2-fluoro- 2-methylpropyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A49	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206048&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968135	321901612							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136236	COc6cc(N5CCC4(CCN(C(=O)CN3Cc2cnc(C(=O)N[C@H]1CCC(=O)NC1=O)cc2C3)CC4)CC5)ccc6[C@@H]9c8[nH]c7ccccc7c8CCN9CC(C)F	InChI=1S/C45H53FN8O5/c1-28(46)24-54-16-11-33-32-5-3-4-6-35(32)48-41(33)42(54)34-8-7-31(22-38(34)59-2)52-17-12-45(13-18-52)14-19-53(20-15-45)40(56)27-51-25-29-21-37(47-23-30(29)26-51)44(58)49-36-9-10-39(55)50-43(36)57/h3-8,21-23,28,36,42,48H,9-20,24-27H2,1-2H3,(H,49,58)(H,50,55,57)	SLSOWOBXZVNTTI-UHFFFAOYSA-N	206050	2-(2-(9-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-methyl-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)-3,9- diazaspiro[5.5]undecan-3-yl)-2-oxoethyl)- N-((S)-2,6-dioxopiperidin-3-yl)-2,3- dihydro-1H-pyrrolo[3,4-c]pyridine-6- carboxamide::US20260007681, Compound A50	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206050	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206050&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968136	321901613							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136237	COc6cc(N5CCC(CN4CCN3c2ccc(C(=O)NC1CCC(=O)NC1=O)nc2OC[C@H]3C4)CC5)ccc6[C@@H]9c8[nH]c7ccccc7c8C[C@@H](C)N9CC(F)F	InChI=1S/C43H50F2N8O5/c1-25-19-31-29-5-3-4-6-32(29)46-39(31)40(53(25)23-37(44)45)30-8-7-27(20-36(30)57-2)51-15-13-26(14-16-51)21-50-17-18-52-28(22-50)24-58-43-35(52)11-9-34(48-43)41(55)47-33-10-12-38(54)49-42(33)56/h3-9,11,20,25-26,28,33,37,40,46H,10,12-19,21-24H2,1-2H3,(H,47,55)(H,49,54,56)	VPOZGRAOIJNXPP-UHFFFAOYSA-N	206052	(4aR)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-N- (2,6-dioxopiperidin-3-yl)-1,2,3,4,4a,5- hexahydropyrazino[1,2-d]pyrido[2,3- b][1,4]oxazine-8-carboxamide::US20260007681, Compound A51	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206052&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968133	321901614							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136238	COc5cc(N4CCC(CN3CCN(c2ccc(C(=O)NC1CCC(=O)NC1=O)nc2OC)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(C)F	InChI=1S/C44H55FN8O5/c1-27(45)25-53-28(2)23-33-31-7-5-6-8-34(31)46-40(33)41(53)32-10-9-30(24-38(32)57-3)51-17-15-29(16-18-51)26-50-19-21-52(22-20-50)37-13-11-36(48-44(37)58-4)42(55)47-35-12-14-39(54)49-43(35)56/h5-11,13,24,27-29,35,41,46H,12,14-23,25-26H2,1-4H3,(H,47,55)(H,49,54,56)	XPCHMXUOYJVUNV-UHFFFAOYSA-N	206053	5-(4-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-methyl-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-(2,6- dioxopiperidin-3-yl)-6- methoxypicolinamide::US20260007681, Compound A52	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206053	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206053&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67968073	321901615							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136239	COc5cc(N4CCC(CN3CCC(c2ccc(C(=O)NC1CCC(=O)NC1=O)nc2)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F	InChI=1S/C43H51F2N7O4/c1-26-21-33-31-5-3-4-6-34(31)47-40(33)41(52(26)25-38(44)45)32-9-8-30(22-37(32)56-2)51-19-13-27(14-20-51)24-50-17-15-28(16-18-50)29-7-10-35(46-23-29)42(54)48-36-11-12-39(53)49-43(36)55/h3-10,22-23,26-28,36,38,41,47H,11-21,24-25H2,1-2H3,(H,48,54)(H,49,53,55)	PSTKJQAXKQRKKT-UHFFFAOYSA-N	206054	5-(1-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-methyl-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperidin-4-yl)-N-(2,6- dioxopiperidin-3-yl)picolinamide::US20260007681, Compound A53	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206054	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206054&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67958891	321901616							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136240	COc6cc(N5CCC(CN4CCN3c2ccc(C(=O)NC1CCC(=O)NC1=O)nc2OC[C@H]3C4)CC5)ccc6[C@H]9c8[nH]c7ccccc7c8C[C@H](C)N9CC(F)F	InChI=1S/C43H50F2N8O5/c1-25-19-31-29-5-3-4-6-32(29)46-39(31)40(53(25)23-37(44)45)30-8-7-27(20-36(30)57-2)51-15-13-26(14-16-51)21-50-17-18-52-28(22-50)24-58-43-35(52)11-9-34(48-43)41(55)47-33-10-12-38(54)49-42(33)56/h3-9,11,20,25-26,28,33,37,40,46H,10,12-19,21-24H2,1-2H3,(H,47,55)(H,49,54,56)	VPOZGRAOIJNXPP-UHFFFAOYSA-N	206055	(4aR)-3-((1-(4-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-N- (2,6-dioxopiperidin-3-yl)-1,2,3,4,4a,5- hexahydropyrazino[1,2-d]pyrido[2,3- b][1,4]oxazine-8-carboxamide::US20260007681, Compound A54	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206055&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67958721	321901617							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136241	COc5cc(N4CCC(CN3CCN(c2ccc(C(=O)N[C@H]1CCC(=O)NC1=O)nc2)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F	InChI=1S/C42H50F2N8O4/c1-26-21-32-30-5-3-4-6-33(30)46-39(32)40(52(26)25-37(43)44)31-9-7-28(22-36(31)56-2)50-15-13-27(14-16-50)24-49-17-19-51(20-18-49)29-8-10-34(45-23-29)41(54)47-35-11-12-38(53)48-42(35)55/h3-10,22-23,26-27,35,37,40,46H,11-21,24-25H2,1-2H3,(H,47,54)(H,48,53,55)	OYMOSSFRFJBEGC-UHFFFAOYSA-N	206056	5-(4-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-methyl-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((S)-2,6- dioxopiperidin-3-yl)picolinamide::US20260007681, Compound A55	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206056&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67959973	321901618							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136242	COc5cc(N4CCC(CN3CCN(c2cnc(C(=O)NC1CCC(=O)NC1=O)cc2OC)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F	InChI=1S/C43H52F2N8O5/c1-26-20-31-29-6-4-5-7-32(29)47-40(31)41(53(26)25-38(44)45)30-9-8-28(21-36(30)57-2)51-14-12-27(13-15-51)24-50-16-18-52(19-17-50)35-23-46-34(22-37(35)58-3)43(56)48-33-10-11-39(54)49-42(33)55/h4-9,21-23,26-27,33,38,41,47H,10-20,24-25H2,1-3H3,(H,48,56)(H,49,54,55)	FYKMOMHFGMBFIP-UHFFFAOYSA-N	206057	5-(4-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-methyl-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-(2,6- dioxopiperidin-3-yl)-4- methoxypicolinamide::US20260007681, Compound A56	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		>5000							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206057	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206057&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67960216	321901619							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136243	COc5cc(N4CCC(CN3CCN(c2ccc(C(=O)N[C@@H]1CCC(=O)NC1=O)nc2)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F	InChI=1S/C42H50F2N8O4/c1-26-21-32-30-5-3-4-6-33(30)46-39(32)40(52(26)25-37(43)44)31-9-7-28(22-36(31)56-2)50-15-13-27(14-16-50)24-49-17-19-51(20-18-49)29-8-10-34(45-23-29)41(54)47-35-11-12-38(53)48-42(35)55/h3-10,22-23,26-27,35,37,40,46H,11-21,24-25H2,1-2H3,(H,47,54)(H,48,53,55)	OYMOSSFRFJBEGC-UHFFFAOYSA-N	206058	5-(4-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-methyl-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((R)-2,6- dioxopiperidin-3-yl)picolinamide formate::US20260007681, Compound A57	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		<50							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206058	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206058&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			67960058	321901620							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136244	C[C@H]%11Cc1c([nH]c2ccccc12)[C@H](c%10cnc(N3CCC9(CC3)C[C@H](CN8CCN7c6ccc5C(=O)N([C@@H]4CCC(=O)NC4=O)Cc5c6OC[C@@H]7C8)CO9)nc%10)N%11CC(F)F	InChI=1S/C45H51F2N9O5/c1-26-16-32-30-4-2-3-5-34(30)50-39(32)40(55(26)23-37(46)47)28-18-48-44(49-19-28)53-12-10-45(11-13-53)17-27(24-61-45)20-52-14-15-54-29(21-52)25-60-41-33-22-56(36-8-9-38(57)51-42(36)58)43(59)31(33)6-7-35(41)54/h2-7,18-19,26-27,29,36-37,40,50H,8-17,20-25H2,1H3,(H,51,57,58)	PLUMUKVJAXKYNF-UHFFFAOYSA-N	206763	(R)-3-((S)-7-(((R)-8-(5-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-1-oxo-1,3,5,5a,6,7,8,9- octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A58	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206763	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206763&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			76955645	322057374							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136245	C[C@H]%11Cc1c([nH]c2ccccc12)[C@H](c%10cnc(N3CCC9(CC3)C[C@@H](CN8CCN7c6ccc5C(=O)N([C@@H]4CCC(=O)NC4=O)Cc5c6OC[C@@H]7C8)CO9)nc%10)N%11CC(F)F	InChI=1S/C45H51F2N9O5/c1-26-16-32-30-4-2-3-5-34(30)50-39(32)40(55(26)23-37(46)47)28-18-48-44(49-19-28)53-12-10-45(11-13-53)17-27(24-61-45)20-52-14-15-54-29(21-52)25-60-41-33-22-56(36-8-9-38(57)51-42(36)58)43(59)31(33)6-7-35(41)54/h2-7,18-19,26-27,29,36-37,40,50H,8-17,20-25H2,1H3,(H,51,57,58)	PLUMUKVJAXKYNF-UHFFFAOYSA-N	206764	(R)-3-((S)-7-(((S)-8-(5-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-1-oxo-1,3,5,5a,6,7,8,9- octahydro-2H- pyrazino[1'2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A59	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206764	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206764&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			86729807	322057375							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136246	C[C@H]%11Cc1c([nH]c2ccccc12)[C@H](c%10cnc(N3CCC9(CC3)C[C@H](CN8CCN7c6cc5CN([C@@H]4CCC(=O)NC4=O)C(=O)c5cc6OC[C@H]7C8)CO9)nc%10)N%11CC(F)F	InChI=1S/C45H51F2N9O5/c1-26-14-33-31-4-2-3-5-34(31)50-40(33)41(55(26)23-38(46)47)29-18-48-44(49-19-29)53-10-8-45(9-11-53)17-27(24-61-45)20-52-12-13-54-30(22-52)25-60-37-16-32-28(15-36(37)54)21-56(43(32)59)35-6-7-39(57)51-42(35)58/h2-5,15-16,18-19,26-27,30,35,38,41,50H,6-14,17,20-25H2,1H3,(H,51,57,58)	ZUJQZWBFRDDBCA-UHFFFAOYSA-N	206765	(R)-3-((R)-3-(((R)-8-(5-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-8-oxo-1,2,3,4,4a,5,8,10- octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A60	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206765	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206765&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			86729808	322057376							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136247	C[C@H]%11Cc1c([nH]c2ccccc12)[C@H](c%10cnc(N3CCC9(CC3)C[C@@H](CN8CCN7c6cc5CN([C@@H]4CCC(=O)NC4=O)C(=O)c5cc6OC[C@H]7C8)CO9)nc%10)N%11CC(F)F	InChI=1S/C45H51F2N9O5/c1-26-14-33-31-4-2-3-5-34(31)50-40(33)41(55(26)23-38(46)47)29-18-48-44(49-19-29)53-10-8-45(9-11-53)17-27(24-61-45)20-52-12-13-54-30(22-52)25-60-37-16-32-28(15-36(37)54)21-56(43(32)59)35-6-7-39(57)51-42(35)58/h2-5,15-16,18-19,26-27,30,35,38,41,50H,6-14,17,20-25H2,1H3,(H,51,57,58)	ZUJQZWBFRDDBCA-UHFFFAOYSA-N	206766	(R)-3-((R)-3-(((S)-8-(5-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-8-oxo-1,2,3,4,4a,5,8,10- octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A61	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206766	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206766&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			78322374	322057377							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136248	C[C@H]%10Cc1c([nH]c2ccccc12)[C@H](c9ccc(N8CCC(CN7CCN6c5ccc4C(=O)N([C@@H]3CCC(=O)NC3=O)Cc4c5OC[C@@H]6C7)CC8)cn9)N%10CC(F)(F)F	InChI=1S/C43H47F3N8O4/c1-25-18-31-29-4-2-3-5-33(29)48-38(31)39(54(25)24-43(44,45)46)34-8-6-27(19-47-34)51-14-12-26(13-15-51)20-50-16-17-52-28(21-50)23-58-40-32-22-53(36-10-11-37(55)49-41(36)56)42(57)30(32)7-9-35(40)52/h2-9,19,25-26,28,36,39,48H,10-18,20-24H2,1H3,(H,49,55,56)	HAYVMVVVUBVUSG-UHFFFAOYSA-N	206767	(R)-3-((S)-7-((1-(6-((1R,3S)-3-methyl-2- (2,2,2-trifluoroethyl)-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyridin-3- yl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A62	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206767	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206767&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			86729810	322057378							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136249	C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N3CCC8(CC3)C[C@@H](CN7CCN6c5ccc(C(=O)N[C@H]4CCC(=O)NC4=O)nc5OC[C@H]6C7)CO8)nc9)N%10CC(F)F	InChI=1S/C43H50F2N10O5/c1-25-16-30-29-4-2-3-5-31(29)48-37(30)38(55(25)22-35(44)45)27-18-46-42(47-19-27)53-12-10-43(11-13-53)17-26(23-60-43)20-52-14-15-54-28(21-52)24-59-41-34(54)8-6-33(50-41)39(57)49-32-7-9-36(56)51-40(32)58/h2-6,8,18-19,25-26,28,32,35,38,48H,7,9-17,20-24H2,1H3,(H,49,57)(H,51,56,58)	YNHWAMPKCMEBHW-UHFFFAOYSA-N	206768	(R)-3-(((S)-8-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-N-((S)-2,6-dioxopiperidin-3- yl)-1,2,3,4,4a,5-hexahydropyrazino[1,2- d]pyrido[2,3-b][1,4]oxazine-8- carboxamide::US20260007681, Compound A63	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206768	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206768&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			78322694	322057379							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136250	C[C@H]%10Cc1c([nH]c2ccccc12)[C@H](c9ccc(N8CCC(CN7CCN6c5cc4CN([C@@H]3CCC(=O)NC3=O)C(=O)c4cc5OC[C@H]6C7)CC8)cn9)N%10CC(F)(F)F	InChI=1S/C43H47F3N8O4/c1-25-16-32-30-4-2-3-5-33(30)48-39(32)40(54(25)24-43(44,45)46)34-7-6-28(19-47-34)51-12-10-26(11-13-51)20-50-14-15-52-29(22-50)23-58-37-18-31-27(17-36(37)52)21-53(42(31)57)35-8-9-38(55)49-41(35)56/h2-7,17-19,25-26,29,35,40,48H,8-16,20-24H2,1H3,(H,49,55,56)	SVVDXJZOIJVQTJ-UHFFFAOYSA-N	226308	(R)-3-((R)-3-((1-(6-((1R,3S)-3-methyl-2- (2,2,2-trifluoroethyl)-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyridin-3- yl)piperidin-4-yl)methyl)-8-oxo- 1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A64	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=226308	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=226308&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			118497150	336293456							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136251	C[C@@H]%10Cc1c([nH]c2ccccc12)[C@H](c9cnc(N3CCC8(CC3)C[C@@H](CN7CCN6c5ccc(C(=O)N[C@H]4CCC(=O)NC4=O)nc5OC[C@H]6C7)CO8)nc9)N%10CC(F)F	InChI=1S/C43H50F2N10O5/c1-25-16-30-29-4-2-3-5-31(29)48-37(30)38(55(25)22-35(44)45)27-18-46-42(47-19-27)53-12-10-43(11-13-53)17-26(23-60-43)20-52-14-15-54-28(21-52)24-59-41-34(54)8-6-33(50-41)39(57)49-32-7-9-36(56)51-40(32)58/h2-6,8,18-19,25-26,28,32,35,38,48H,7,9-17,20-24H2,1H3,(H,49,57)(H,51,56,58)	YNHWAMPKCMEBHW-UHFFFAOYSA-N	226309	(R)-3-(((S)-8-(5-((1S,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-N-((S)-2,6-dioxopiperidin-3- yl)-1,2,3,4,4a,5-hexahydropyrazino[1,2- d]pyrido[2,3-b][1,4]oxazine-8- carboxamide::US20260007681, Compound A65	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=226309	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=226309&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			118497102	336293457					C04080		2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136252	C[C@H]9Cc1c([nH]c2ccccc12)[C@H](c8cnc(N3CCC7(CC3)C[C@@H](CN6CCC(c5ccc(N[C@@H]4CCC(=O)NC4=O)cc5)CC6)CO7)nc8)N9CC(F)F	InChI=1S/C43H52F2N8O3/c1-27-20-34-33-4-2-3-5-35(33)49-39(34)40(53(27)25-37(44)45)31-22-46-42(47-23-31)52-18-14-43(15-19-52)21-28(26-56-43)24-51-16-12-30(13-17-51)29-6-8-32(9-7-29)48-36-10-11-38(54)50-41(36)55/h2-9,22-23,27-28,30,36-37,40,48-49H,10-21,24-26H2,1H3,(H,50,54,55)	RZFDGDVHVIXWFC-UHFFFAOYSA-N	226310	(R)-3-((4-(1-(((S)-8-(5-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)piperidin-4- yl)phenyl)amino)piperidine-2,6-dione::US20260007681, Compound A66	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=226310	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=226310&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			118497066	336293458							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136253	C[C@H]9Cc1c([nH]c2ccccc12)[C@H](c8cnc(N3CCC7(CC3)C[C@H](CN6CCC(c5ccc(N[C@H]4CCC(=O)NC4=O)cc5)CC6)CO7)nc8)N9CC(F)F	InChI=1S/C43H52F2N8O3/c1-27-20-34-33-4-2-3-5-35(33)49-39(34)40(53(27)25-37(44)45)31-22-46-42(47-23-31)52-18-14-43(15-19-52)21-28(26-56-43)24-51-16-12-30(13-17-51)29-6-8-32(9-7-29)48-36-10-11-38(54)50-41(36)55/h2-9,22-23,27-28,30,36-37,40,48-49H,10-21,24-26H2,1H3,(H,50,54,55)	RZFDGDVHVIXWFC-UHFFFAOYSA-N	226311	(S)-3-((4-(1-(((R)-8-(5-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)piperidin-4- yl)phenyl)amino)piperidine-2,6-dione::US20260007681, Compound A67	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=226311	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=226311&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			118497118	336293459							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136254	C[C@H]%11Cc1c([nH]c2ccccc12)[C@H](c%10cnc(N3CCC9(CC3)C[C@@H](CN8CCN7c6cc5CN([C@@H]4CCC(=O)NC4=O)C(=O)c5cc6OC[C@@H]7C8)CO9)nc%10)N%11CC(F)F	InChI=1S/C45H51F2N9O5/c1-26-14-33-31-4-2-3-5-34(31)50-40(33)41(55(26)23-38(46)47)29-18-48-44(49-19-29)53-10-8-45(9-11-53)17-27(24-61-45)20-52-12-13-54-30(22-52)25-60-37-16-32-28(15-36(37)54)21-56(43(32)59)35-6-7-39(57)51-42(35)58/h2-5,15-16,18-19,26-27,30,35,38,41,50H,6-14,17,20-25H2,1H3,(H,51,57,58)	ZUJQZWBFRDDBCA-UHFFFAOYSA-N	226312	(R)-3-((S)-3-(((S)-8-(5-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-8-oxo-1,2,3,4,4a,5,8,10- octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A68	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 2750							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=226312	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=226312&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			118497067	336293460							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136677	C[C@H]%11Cc1c([nH]c2ccccc12)[C@H](c%10cnc(N3CCC9(CC3)C[C@H](CN8CCN7c6cc5CN([C@@H]4CCC(=O)NC4=O)C(=O)c5cc6OC[C@@H]7C8)CO9)nc%10)N%11CC(F)F	InChI=1S/C45H51F2N9O5/c1-26-14-33-31-4-2-3-5-34(31)50-40(33)41(55(26)23-38(46)47)29-18-48-44(49-19-29)53-10-8-45(9-11-53)17-27(24-61-45)20-52-12-13-54-30(22-52)25-60-37-16-32-28(15-36(37)54)21-56(43(32)59)35-6-7-39(57)51-42(35)58/h2-5,15-16,18-19,26-27,30,35,38,41,50H,6-14,17,20-25H2,1H3,(H,51,57,58)	ZUJQZWBFRDDBCA-UHFFFAOYSA-N	226314	(R)-3-((S)-3-(((R)-8-(5-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-8-oxo-1,2,3,4,4a,5,8,10- octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A69	DNA damage-binding protein 1/Protein cereblon	Homo sapiens		 275							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=226314	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=6&target=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=226314&enzyme=DNA+damage-binding+protein+1%2FProtein+cereblon&column=ki&startPg=0&Increment=50&submit=Search			118506964	336293461							2	MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH	9J6K,9W90,9W2F,9S3R,9OS2,9NGT,9NFR,9NFQ,9M0Y,9LWL,9LWJ,9LWI,9LU1,9LTZ,9LTW,9LTR,9LTO,9LTL,9LTJ,9IVD,9HNE,9H59,9DWV,9C5V,9C5U,9C5T,9BBI,9BBH,9BBG,9BBE,8WQR,8T9A,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,7V7C,7V7B,7UKN,7LPS,6ZX9,6ZUE,6XK9,6UML,6SJ7,6PAI,6DSZ,5V3O,5JK7,5HXB,3E0C,10AY,8QH5,8ZSW,8UH6,9SFM,9NYR,9FJX,9D0W,8OJH,8OIZ,6R8Y,4A0L,9U7T,6R92,6R91,6R90,6R8Z,8AJO,8AJN,8AJM,7OKQ,4A11,4A0K,6FCV,4CI3,4CI2,4CI1,3EI3,3EI2,3EI1,4TZ4,9DHD,4E5Z,4E54,9FMR,9E2U,8TL6,8G46,6Q0W,6Q0V,6Q0R,6BOY,6BNB,6BN9,6BN8,6BN7,9SAI,9SAF,9Q2D,9HPJ,9HPI,9DWW,9DQD,9DJX,9DJT,9BJZ,8U17,8U16,8U15,8TZX,8ROY,8ROX,8OV6,8DEY,8D81,7U8F,6UE5,6UD7,8BUT,8BUS,8BUR,8BUQ,8BUP,8BUO,8BUN,8BUM,8BUL,8BUK,8BUJ,8BUI,8BUH,8BUG,8BUF,8BUE,8BUD,8BUC,8BUB,8BUA,8BU9,8BU7,8BU6,8BU5,8BU4,8BU3,8BU2,8BU1,6TD3,9ZXN,9ZXM,9Q22,9OUL,9OUK,9NWT,9NWS,8TNR,8TNQ,8TNP,8G66,6H0G,6H0F,5FQD,9NR3,9OTY	DNA damage-binding protein 1	DDB1_HUMAN	Q16531	A6NG77 B2R648 B4DG00 O15176 Q13289 Q58F96							MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL	9NWT,9NWS,9DUR,8TNR,8TNQ,8TNP,9DWW,9DWV,9Q33,9OUK,9NGT,9NFR,9NFQ,8D81,8D80,8D7Z,8D7Y,8D7X,8D7W,8D7V,8D7U,8CVP,9YA9,9Q2D,9Q03,9DQD,8UH6,9SAI,9SAF,9H59,9E2U,6BOY,6BNB,6BN9,6BN8,6BN7,9OUL,9Y7D,6XK9,6UML,5V3O,5HXB,9NYR,9HNE,9D0X,9D0W,7U8F,9FJX,8OJH,8OIZ,11MR,10AY,9NR3,9HPJ,9HPI,7LPS,9SFM,9OTY,4TZ4,9W2F,9OS2,9DJX,9DJT,8U17,8U16,8U15,8TZX,8DEY,9CUO,4M91	Protein cereblon	CRBN_HUMAN	Q96SW2	B2R6H4 C9IZA9 C9JAH6 Q6AI62 Q6NVZ0 Q9UHW4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
136678	COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@H]1CCC(=O)NC1=O)Cc2c3OC[C@@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-19-33-30-5-3-4-6-35(30)48-41(33)42(53(26)24-39(46)47)32-8-7-28(20-38(32)58-2)51-15-13-27(14-16-51)21-50-17-18-52-29(22-50)25-59-43-34-23-54(37-11-12-40(55)49-44(37)56)45(57)31(34)9-10-36(43)52/h3-10,20,26-27,29,37,39,42,48H,11-19,21-25H2,1-2H3,(H,49,55,56)	WJHSKRHFCXEXIR-UHFFFAOYSA-N	206006	(S)-3-((S)-7-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A12	Estrogen receptor [282-595]			<10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206006	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206006&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			57387856	321901575							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136679	COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@H]1CCC(=O)NC1=O)Cc2c3OC[C@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-19-33-30-5-3-4-6-35(30)48-41(33)42(53(26)24-39(46)47)32-8-7-28(20-38(32)58-2)51-15-13-27(14-16-51)21-50-17-18-52-29(22-50)25-59-43-34-23-54(37-11-12-40(55)49-44(37)56)45(57)31(34)9-10-36(43)52/h3-10,20,26-27,29,37,39,42,48H,11-19,21-25H2,1-2H3,(H,49,55,56)	WJHSKRHFCXEXIR-UHFFFAOYSA-N	206013	(S)-3-((R)-7-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- c]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A19	Estrogen receptor [282-595]			<10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206013	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206013&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			57387134	321901582							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136680	COc7cc(N6CCC(CN5CCN4c3cc2CN([C@H]1CCC(=O)NC1=O)C(=O)c2cc3OC[C@@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-17-34-31-5-3-4-6-35(31)48-42(34)43(53(26)24-40(46)47)32-8-7-29(19-38(32)58-2)51-13-11-27(12-14-51)21-50-15-16-52-30(23-50)25-59-39-20-33-28(18-37(39)52)22-54(45(33)57)36-9-10-41(55)49-44(36)56/h3-8,18-20,26-27,30,36,40,43,48H,9-17,21-25H2,1-2H3,(H,49,55,56)	ZHTPIQFRAPUAAQ-UHFFFAOYSA-N	206022	(S)-3-((S)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)- 8-oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A28	Estrogen receptor [282-595]			<10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206022	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206022&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			67968121	321901591							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136681	COc7cc(N6CCC(CN5CCN4c3cc2CN([C@H]1CCC(=O)NC1=O)C(=O)c2cc3OC[C@@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-17-34-31-5-3-4-6-35(31)48-42(34)43(53(26)24-40(46)47)32-8-7-29(19-38(32)58-2)51-13-11-27(12-14-51)21-50-15-16-52-30(23-50)25-59-39-20-33-28(18-37(39)52)22-54(45(33)57)36-9-10-41(55)49-44(36)56/h3-8,18-20,26-27,30,36,40,43,48H,9-17,21-25H2,1-2H3,(H,49,55,56)	ZHTPIQFRAPUAAQ-UHFFFAOYSA-N	206023	(S)-3-((S)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A29	Estrogen receptor [282-595]			<10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206023	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206023&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			67968126	321901592							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136682	C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N8CCC(CN3CCC7(CC3)COc6cc5C(=O)N(C4CCC(=O)NC4=O)Cc5cc67)CC8)nc9)N%10CC(F)(F)CO	InChI=1S/C44H50F2N8O5/c1-26-16-32-30-4-2-3-5-34(30)49-38(32)39(54(26)23-44(45,46)24-55)29-19-47-42(48-20-29)52-12-8-27(9-13-52)21-51-14-10-43(11-15-51)25-59-36-18-31-28(17-33(36)43)22-53(41(31)58)35-6-7-37(56)50-40(35)57/h2-5,17-20,26-27,35,39,49,55H,6-16,21-25H2,1H3,(H,50,56,57)	RNFIEXJKUWCZCC-UHFFFAOYSA-N	206030	3-(1'-((1-(5-((1R,3R)-2-(2,2-difluoro-3- hydroxypropyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1- yl)pyrimidin-2-yl)piperidin-4-yl)methyl)- 7-oxo-5,7-dihydro-2H,6H-spiro[furo[2,3- f]isoindole-3,4'-piperidin]-6-yl) piperidine-2,6-dione::US20260007681, Compound A36	Estrogen receptor [282-595]			<10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206030	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206030&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			67968078	321901599							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136683	COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@@H]1CCC(=O)NC1=O)Cc2c3OC[C@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-19-33-30-5-3-4-6-35(30)48-41(33)42(53(26)24-39(46)47)32-8-7-28(20-38(32)58-2)51-15-13-27(14-16-51)21-50-17-18-52-29(22-50)25-59-43-34-23-54(37-11-12-40(55)49-44(37)56)45(57)31(34)9-10-36(43)52/h3-10,20,26-27,29,37,39,42,48H,11-19,21-25H2,1-2H3,(H,49,55,56)	WJHSKRHFCXEXIR-UHFFFAOYSA-N	206031	(R)-3-((R)-7-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A37	Estrogen receptor [282-595]			<10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206031&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			67968076	321901600							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136684	COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@H]1CCC(=O)NC1=O)Cc2c3OC[C@@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F	InChI=1S/C45H51F2N7O5/c1-26-19-33-30-5-3-4-6-35(30)48-41(33)42(53(26)24-39(46)47)32-8-7-28(20-38(32)58-2)51-15-13-27(14-16-51)21-50-17-18-52-29(22-50)25-59-43-34-23-54(37-11-12-40(55)49-44(37)56)45(57)31(34)9-10-36(43)52/h3-10,20,26-27,29,37,39,42,48H,11-19,21-25H2,1-2H3,(H,49,55,56)	WJHSKRHFCXEXIR-UHFFFAOYSA-N	206041	(S)-3-((S)-7-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A45	Estrogen receptor [282-595]			<10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206041	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206041&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			67968132	321901608							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136685	COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@H]1CCC(=O)NC1=O)Cc2c3OC[C@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(C)(C)F	InChI=1S/C47H56FN7O5/c1-28-21-35-32-7-5-6-8-37(32)49-42(35)43(55(28)27-47(2,3)48)34-10-9-30(22-40(34)59-4)52-17-15-29(16-18-52)23-51-19-20-53-31(24-51)26-60-44-36-25-54(39-13-14-41(56)50-45(39)57)46(58)33(36)11-12-38(44)53/h5-12,22,28-29,31,39,43,49H,13-21,23-27H2,1-4H3,(H,50,56,57)	AEBNLOFIJHRQAU-UHFFFAOYSA-N	206048	(S)-3-((R)-7-((1-(4-((1R,3R)-2-(2-fluoro- 2-methylpropyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A49	Estrogen receptor [282-595]			>10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206048&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			67968135	321901612							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136686	COc6cc(N5CCC(CN4CCN3c2ccc(C(=O)NC1CCC(=O)NC1=O)nc2OC[C@H]3C4)CC5)ccc6[C@@H]9c8[nH]c7ccccc7c8C[C@@H](C)N9CC(F)F	InChI=1S/C43H50F2N8O5/c1-25-19-31-29-5-3-4-6-32(29)46-39(31)40(53(25)23-37(44)45)30-8-7-27(20-36(30)57-2)51-15-13-26(14-16-51)21-50-17-18-52-28(22-50)24-58-43-35(52)11-9-34(48-43)41(55)47-33-10-12-38(54)49-42(33)56/h3-9,11,20,25-26,28,33,37,40,46H,10,12-19,21-24H2,1-2H3,(H,47,55)(H,49,54,56)	VPOZGRAOIJNXPP-UHFFFAOYSA-N	206052	(4aR)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-N- (2,6-dioxopiperidin-3-yl)-1,2,3,4,4a,5- hexahydropyrazino[1,2-d]pyrido[2,3- b][1,4]oxazine-8-carboxamide::US20260007681, Compound A51	Estrogen receptor [282-595]			<10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206052&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			67968133	321901614							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136687	COc5cc(N4CCC(CN3CCN(c2ccc(C(=O)N[C@H]1CCC(=O)NC1=O)nc2)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F	InChI=1S/C42H50F2N8O4/c1-26-21-32-30-5-3-4-6-33(30)46-39(32)40(52(26)25-37(43)44)31-9-7-28(22-36(31)56-2)50-15-13-27(14-16-50)24-49-17-19-51(20-18-49)29-8-10-34(45-23-29)41(54)47-35-11-12-38(53)48-42(35)55/h3-10,22-23,26-27,35,37,40,46H,11-21,24-25H2,1-2H3,(H,47,54)(H,48,53,55)	OYMOSSFRFJBEGC-UHFFFAOYSA-N	206056	5-(4-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-methyl-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((S)-2,6- dioxopiperidin-3-yl)picolinamide::US20260007681, Compound A55	Estrogen receptor [282-595]			<10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206056&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			67959973	321901618							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136688	C[C@H]%11Cc1c([nH]c2ccccc12)[C@H](c%10cnc(N3CCC9(CC3)C[C@@H](CN8CCN7c6ccc5C(=O)N([C@@H]4CCC(=O)NC4=O)Cc5c6OC[C@@H]7C8)CO9)nc%10)N%11CC(F)F	InChI=1S/C45H51F2N9O5/c1-26-16-32-30-4-2-3-5-34(30)50-39(32)40(55(26)23-37(46)47)28-18-48-44(49-19-28)53-12-10-45(11-13-53)17-27(24-61-45)20-52-14-15-54-29(21-52)25-60-41-33-22-56(36-8-9-38(57)51-42(36)58)43(59)31(33)6-7-35(41)54/h2-7,18-19,26-27,29,36-37,40,50H,8-17,20-25H2,1H3,(H,51,57,58)	PLUMUKVJAXKYNF-UHFFFAOYSA-N	206764	(R)-3-((S)-7-(((S)-8-(5-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-1-oxo-1,3,5,5a,6,7,8,9- octahydro-2H- pyrazino[1'2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A59	Estrogen receptor [282-595]			>10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206764	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206764&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			86729807	322057375							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136689	C[C@H]%11Cc1c([nH]c2ccccc12)[C@H](c%10cnc(N3CCC9(CC3)C[C@@H](CN8CCN7c6cc5CN([C@@H]4CCC(=O)NC4=O)C(=O)c5cc6OC[C@H]7C8)CO9)nc%10)N%11CC(F)F	InChI=1S/C45H51F2N9O5/c1-26-14-33-31-4-2-3-5-34(31)50-40(33)41(55(26)23-38(46)47)29-18-48-44(49-19-29)53-10-8-45(9-11-53)17-27(24-61-45)20-52-12-13-54-30(22-52)25-60-37-16-32-28(15-36(37)54)21-56(43(32)59)35-6-7-39(57)51-42(35)58/h2-5,15-16,18-19,26-27,30,35,38,41,50H,6-14,17,20-25H2,1H3,(H,51,57,58)	ZUJQZWBFRDDBCA-UHFFFAOYSA-N	206766	(R)-3-((R)-3-(((S)-8-(5-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-8-oxo-1,2,3,4,4a,5,8,10- octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A61	Estrogen receptor [282-595]			>10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206766	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206766&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			78322374	322057377							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136690	C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N3CCC8(CC3)C[C@@H](CN7CCN6c5ccc(C(=O)N[C@H]4CCC(=O)NC4=O)nc5OC[C@H]6C7)CO8)nc9)N%10CC(F)F	InChI=1S/C43H50F2N10O5/c1-25-16-30-29-4-2-3-5-31(29)48-37(30)38(55(25)22-35(44)45)27-18-46-42(47-19-27)53-12-10-43(11-13-53)17-26(23-60-43)20-52-14-15-54-28(21-52)24-59-41-34(54)8-6-33(50-41)39(57)49-32-7-9-36(56)51-40(32)58/h2-6,8,18-19,25-26,28,32,35,38,48H,7,9-17,20-24H2,1H3,(H,49,57)(H,51,56,58)	YNHWAMPKCMEBHW-UHFFFAOYSA-N	206768	(R)-3-(((S)-8-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-N-((S)-2,6-dioxopiperidin-3- yl)-1,2,3,4,4a,5-hexahydropyrazino[1,2- d]pyrido[2,3-b][1,4]oxazine-8- carboxamide::US20260007681, Compound A63	Estrogen receptor [282-595]			>10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=206768	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=206768&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			78322694	322057379							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136691	C[C@H]%11Cc1c([nH]c2ccccc12)[C@H](c%10cnc(N3CCC9(CC3)C[C@H](CN8CCN7c6cc5CN([C@@H]4CCC(=O)NC4=O)C(=O)c5cc6OC[C@@H]7C8)CO9)nc%10)N%11CC(F)F	InChI=1S/C45H51F2N9O5/c1-26-14-33-31-4-2-3-5-34(31)50-40(33)41(55(26)23-38(46)47)29-18-48-44(49-19-29)53-10-8-45(9-11-53)17-27(24-61-45)20-52-12-13-54-30(22-52)25-60-37-16-32-28(15-36(37)54)21-56(43(32)59)35-6-7-39(57)51-42(35)58/h2-5,15-16,18-19,26-27,30,35,38,41,50H,6-14,17,20-25H2,1H3,(H,51,57,58)	ZUJQZWBFRDDBCA-UHFFFAOYSA-N	226314	(R)-3-((S)-3-(((R)-8-(5-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-8-oxo-1,2,3,4,4a,5,8,10- octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A69	Estrogen receptor [282-595]			>10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=226314	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=226314&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			118506964	336293461							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
136692	C[C@@H]9Cc1c([nH]c2ccccc12)[C@@H](c8cnc(N3CCC7(CC3)C[C@@H](CN6CCC(c5ccc(N[C@@H]4CCC(=O)NC4=O)cc5)CC6)CO7)nc8)N9CC(F)F	InChI=1S/C43H52F2N8O3/c1-27-20-34-33-4-2-3-5-35(33)49-39(34)40(53(27)25-37(44)45)31-22-46-42(47-23-31)52-18-14-43(15-19-52)21-28(26-56-43)24-51-16-12-30(13-17-51)29-6-8-32(9-7-29)48-36-10-11-38(54)50-41(36)55/h2-9,22-23,27-28,30,36-37,40,48-49H,10-21,24-26H2,1H3,(H,50,54,55)	RZFDGDVHVIXWFC-UHFFFAOYSA-N	226315	(R)-3-((4-(1-(((S)-8-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)piperidin-4- yl)phenyl)amino)piperidine-2,6-dione::US20260007681, Compound A70	Estrogen receptor [282-595]			<10.00							US Patent		10.7270/Q2QZ2GSN			US20260007681	Rej, R; Chen, Z; Wang, M; Wu, D; Xu, G; Acharyya, RK; Hu, B; Lu, J; Wang, S	1/8/2026	5/20/2026	University Of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=226315	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1666&target=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=226315&enzyme=Estrogen+receptor+%5B282-595%5D&column=ki&startPg=0&Increment=50&submit=Search			118508010	336293462							1	SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV	3ERT,3ERD,1R5K,1L2I,2IOK,2OUZ,1ERR,1ERE,3DT3,2YJA,3L03,3HM1,3HLV,3UUC,1QKU	Estrogen receptor	ESR1_HUMAN	P03372	Q13511 Q14276 Q5T5H7 Q6MZQ9 Q9NU51 Q9UDZ7 Q9UIS7