BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
1572162	F/C=C\9CN1CCC[C@@]1(COc6nc7c5c(nc(c3c(C2CC2)c(Cl)cc4[nH]ncc34)c(F)c5n6)OC[C@@H]8COCCCN78)C9			785344	US12466840, Example Ex-1	GTPase KRas [G12D]	Homo sapiens		 0.670							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1006&target=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785344&enzyme=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JHL,7NY8,6YXW,6MQN,7W5R,7C41,7C40,6YR8,5UK9,5UFE,7RSE,7RSC,6W4E,9KFL,4TQ9,5OCG,4DSU,4DST,4DSO,4DSN,6W4F,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8QVU,5WPM,5WLB,6P0Z,5VQ0,5VPZ,5VPY,5VPI,5VP7,5V9O,5V9L,5V71,5KYK,6M9W,5WHB,5WHA,9BG5,6GOE,8EPW,8EBZ,7KFZ,6XGV,6OB3,7RP3,8AFC,9UOH,8X6R,8V3A,8V39	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572163	F/C=C\9CN1CCC[C@@]1(COc6nc7c5c(nc(c3c(C2CC2)c(Cl)cc4[nH]ncc34)c(F)c5n6)OC[C@@H]8COCCCN78)C9			785344	US12466840, Example Ex-1	GTPase KRas [G12V]	Homo sapiens		 1.30							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1398&target=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785344&enzyme=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8PI0,7NY8,6YXW,6MQN,5V9O,5V9L,5V71,5KYK,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GJ8,9C41,5UK9,5UFE,6YR8,6WS4,9C43,5UFQ,7ROV,9C3Q,7RP3,8STN,6P0Z,5WHE,5WHD,7F0W,7EYX,9C3R,7XKJ,9RKC,9P45,9P44,9GBJ,9C40,8AZY,6ZL5,6GJ5,4EPR,6M9W,8AFC,9BG5,9U99,9U90,9U8Z,9U8U,8FMK,8FMJ,11QE,8EPW,8EBZ,7KFZ,6XGV,6OB3,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9E9I,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3N,9C3M,9U95,9U8W,9U97,9U8Y,9U8V	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10		small monomeric GTPase	L7RSL8_HUMAN	L7RSL8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1572164	F/C=C\9CN1CCC[C@@]1(COc6nc7c5c(nc(c3c(C2CC2)c(Cl)cc4[nH]ncc34)c(F)c5n6)OC[C@@H]8COCCCN78)C9			785344	US12466840, Example Ex-1	GTPase KRas	Homo sapiens		 0.870							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006227&target=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785344&enzyme=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7VVB,8T75,8T74,8T72,8T71,6FA1,6GOM,6FA3,6ASA,6FA2,6GQX,6GQT,6GQY,6GQW,6GJ8,4TQA,7W5R,7C41,7C40,6BOF,6MBQ,9KFL,7ROV,6O36,5VQ0,5VPZ,5VPY,5VPI,5VP7,6E6G,6E6F,5UFQ,4TQ9,6O46,9C41,6WS4,9C3Q,8G4F,6H47,6H46,5V9O,5V9L,5V71,5O2T,5O2S,5MLB,5MLA,5KYK,8STN,5WPM,5WLB,7F0W,7EYX,9C43,8UN4,7XKJ,8FMK,8FMJ,9C40,9RKC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572165	F/C=C\9CN1CCC[C@@]1(COc6nc7c5c(nc(c3c(C2CC2)c(Cl)cc4[nH]ncc34)c(F)c5n6)OC[C@@H]8COCCCN78)C9			785344	US12466840, Example Ex-1	GTPase KRas [G12C]	Homo sapiens		 6.90							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=864&target=GTPase+KRas+%5BG12C%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785344&enzyme=GTPase+KRas+%5BG12C%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JGD,7W5R,7C41,7C40,9KFL,4TQ9,5WPM,5WLB,7NY8,6YXW,6MQN,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,5VQ0,5VPZ,5VPY,5VPI,5VP7,6YR8,6GJ8,5UK9,5UFE,5WHB,5WHA,6GOE,5UFQ,6WS4,9C41,9C3Q,6P0Z,7ROV,9C43,7F0W,7EYX,6M9W,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,8STN,7XKJ,8FMK,8FMJ,9BG5,9C40,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3R,9U99,9U90	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572166	F/C=C\9CN1CCC[C@@]1(COc6nc7c5c(nc(c3c(C2CC2)c(Cl)cc4[nH]ncc34)c(F)c5n6)OC[C@@H]8COCCCN78)C9			785344	US12466840, Example Ex-1	GTPase KRas [G13D]	Homo sapiens		 3.70							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1403&target=GTPase+KRas+%5BG13D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785344&enzyme=GTPase+KRas+%5BG13D%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGDVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8CPR,8BLR,8UN3,8UN5,7NY8,6YXW,6MQN,6YR8,5UK9,5UFE,8TBJ,9BHQ,8TBN,9E3S,7TLK,9BHO,6P0Z,6M9W,9USB,9U5T,9CTB,9CTA,9CT9,9CT8,9CT7,9L6F,9L6A,9E5F,9E5D,9BI1,9BGH,8WB1,8TXH,8TXG,8TXE,8R7X,8R7W,7EWB,7EWA,7EW9,7ACQ,7ACH,7ACF,7ACA,6ZLI,6QUX,6QUW,6QUV,6GJ7,6GJ6,9BGC,8TBH,5XCO,9RKN,9RKJ,9RKE,6CU6,4QL3,6QUU,9BGA,9BFV,8TBK,8G9P,8TY9,8TY8,8TY2,8TXK,8TXJ,8TVK,7MDP,5USJ,5US4,9PIZ,9N9N,9BI2,9BHP,7A47,7A1Y,7A1X,7A1W,4NMM,4LDJ,4L8G,9KPN,9KPM,8G47,8G42,9PZY	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572167	F/C=C\9CN1CCC[C@@]1(COc6nc7c5c(nc(c3c(C2CC2)c(Cl)cc4[nH]ncc34)c(F)c5n6)OC[C@@H]8COCCCN78)C9			785344	US12466840, Example Ex-1	GTPase HRas	Homo sapiens		>11060							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1541&target=GTPase+HRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785344&enzyme=GTPase+HRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS	4Q21,6Q21,1Q21,1IOZ,1AA9,7VV9,6AMB,6KYH,7L0F,6AXG,5E95,8BEA,8BE9,8BE8,8BE7,8BE6,8WWC,8OSO,8OSN,8OSM,8CNN,8CNJ,8BWG,8BOS,7OGC,7OGB,7OGA,7OG9,5P21,4RSG,4NYM,4NYJ,4G0N,4DLW,4DLU,4DLT,4DLS,3TGP,3RSO,3RSL,3RS7,3RS5,3RS4,3RS3,3RS2,3RS0,3RRZ,3RRY,3LBN,3LBI,3LBH,3L8Z,3L8Y,3KUD,3K8Y,2RGE,1XD2,1WQ1,1QRA,1P2V,1P2U,1P2T,1P2S,1NVW,1NVV,1K8R,1GNR,1GNQ,1GNP,1CTQ,1CRR,1CRQ,1CRP,1BKD,121P,8TBG,6ZL3,6V9O,6V9N,6V9M,6V9L,6V9J,6V9F,6V94,6D5W,6D5V,6D5M,6D5L,6D5J,6D5H,6D5G,6D5E,6D59,6D56,6D55,6CUR,6CUP,6CUO,6BVM,6BVL,6BVK,6BVJ,6BVI,5WFR,5WFQ,5WFP,5WFO,4NYI,5WDO,5B30,5B2Z,4EFL,4US2,4US1,4US0,4URZ,4URY,4URX,4URW,4URV,4URU	GTPase HRas	RASH_HUMAN	P01112	B5BUA0 Q14080 Q6FHV9 Q9BR65 Q9UCE2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572168	F/C=C\9CN1CCC[C@@]1(COc6nc7c5c(nc(c3c(C2CC2)c(Cl)cc4[nH]ncc34)c(F)c5n6)OC[C@@H]8COCCCN78)C9			785344	US12466840, Example Ex-1	GTPase NRas	Homo sapiens		>11060							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006303&target=GTPase+NRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785344&enzyme=GTPase+NRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQGCMGLPCVVM	8TBI,3CON,8VM2,6ZIR,6ZIO,9BG0,5UHV,6WGH,4Q21,6MQT,6E6P,6E6C,6DZH,1AGP,421P,6ZJ0,821P,1PLL,1PLJ,1JAI,1CLU,7L0G,8TLR,4L9W,4L9S,1PLK,1JAH	GTPase NRas	RASN_HUMAN	P01111	Q14971 Q15104 Q15282																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572169	F/C=C\9CN1CCC[C@@]1(COc6nc7c5c(nc(c3c(C2CC2)c(Cl)cc4[nH]ncc34)c(F)c5n6)OC[C@@H]8COCCCN78)C9			785344	US12466840, Example Ex-1	GTPase KRas [G12A]	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2069&target=GTPase+KRas+%5BG12A%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785344&enzyme=GTPase+KRas+%5BG12A%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAAGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6MQN,7W5R,7C41,7C40,7NY8,6YXW,9KFL,4TQ9,6YR8,5WPM,5WLB,5UK9,5UFE,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,5V9O,5V9L,5V71,5KYK,6GJ8,5WHB,5WHA,6GOE,9C41,6M9W,7ROV,6WS4,5UFQ,6P0Z,9C43,9BG5,9C3Q,8STN,8EPW,8EBZ,7KFZ,6XGV,6OB3,7F0W,7EYX,7RP3,9C40,7XKJ,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,9C3R,9U99,9U90,8FMK,8FMJ,11QE,9U8Z,9U8U,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,8AFC,9C3K,9C3V,9E9I,9U8X,9U8T,9C3Z,9U8V,9C3N,9C3M,9U95,9U8W,9U97,9U8Y	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572170	F/C=C\9CN1CCC[C@@]1(COc6nc7c5c(nc(c3c(C2CC2)c(Cl)cc4[nH]ncc34)c(F)c5n6)OC[C@@H]8COCCCN78)C9			785344	US12466840, Example Ex-1	GTPase KRas [G12S]	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1374&target=GTPase+KRas+%5BG12S%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785344&enzyme=GTPase+KRas+%5BG12S%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGASGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6MQN,7NY8,6YXW,7W5R,7C41,7C40,6GJ8,9KFL,4TQ9,6YR8,5UK9,5UFE,9C41,5VQ0,5VPZ,5VPY,5VPI,5VP7,5UFQ,5V9O,5V9L,5V71,5KYK,6WS4,7ROV,5WPM,5WLB,9C3Q,9C43,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8STN,7F0W,7EYX,6P0Z,5WHB,5WHA,6M9W,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,6GOE,9C3R,9C40,7XKJ,9BG5,8FMK,8FMJ,11QE,9U99,9U90,7RP3,9U8Z,9U8U,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3M,9C3N,9U8V,8AFC,9U95,9U8W,9E9I,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9U97,9U8Y	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572171	F/C=C\9CN1CCC[C@@]1(COc6nc7c5c(nc(c3c(C2CC2)c(Cl)cc4[nH]ncc34)c(F)c5n6)OC[C@@H]8COCCCN78)C9			785344	US12466840, Example Ex-1	GTPase KRas [G12R]	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2068&target=GTPase+KRas+%5BG12R%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785344&enzyme=GTPase+KRas+%5BG12R%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGARGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7W5R,7C41,7C40,6MQN,7NY8,6YXW,9KFL,6GJ8,4TQ9,9C41,6WS4,5UFQ,5UK9,5UFE,6YR8,9C3Q,7ROV,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,9C43,5WPM,5WLB,8STN,7F0W,7EYX,5WHB,5WHA,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GOE,5V9O,5V9L,5V71,5KYK,6M9W,9C40,7XKJ,6P0Z,9BG5,9C3R,9U8Z,9U8U,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,9U99,9U90,11QE,8FMK,8FMJ,9C3K,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3V,9U8X,9U8T,7RP3,9C3Z,9U95,9U8W,9U8V,9C3N,9C3M,9U97,9U8Y,8AFC,9E9I,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572172	F/C=C\9CN1CCC[C@@]1(COc6nc7c5c(nc(c3c(C2CC2)c(Cl)cc4[nH]ncc34)c(F)c5n6)OC[C@@H]8COCCCN78)C9			785344	US12466840, Example Ex-1	GTPase KRas [Q61H]	Homo sapiens		 1.40							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1404&target=GTPase+KRas+%5BQ61H%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785344&enzyme=GTPase+KRas+%5BQ61H%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGHEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6GQW,6MQN,7NY8,6YXW,8TBJ,5UK9,5UFE,6YR8,8TBN,9E3S,6P0Z,7TLK,9BHQ,9BHO,6M9W,9CTB,9CTA,9CT9,9CT8,9CT7,9BG5,9USB,9U5T,5XCO,9L6F,9L6A,9E5F,9E5D,9BI1,9BGH,8WB1,8TXH,8TXG,8TXE,8R7X,8R7W,8EPW,8EBZ,7KFZ,7EWB,7EWA,7EW9,7ACQ,7ACH,7ACF,7ACA,6ZLI,6XGV,6QUX,6QUW,6QUV,6OB3,6GJ7,6GJ6,9BGC,8TBH,6QUU,9BGA,9BFV,8TBK,8G9P,9RKN,9RKJ,9RKE,6CU6,4QL3,9PIZ,8TY9,8TY8,8TY2,8TXK,8TXJ,8TVK,7MDP,5USJ,5US4,9BI2,9BHP,7A47,7A1Y,7A1X,7A1W,4NMM,4LDJ,4L8G,9N9N,9KPN,9KPM,8G47,8G42,9PZY	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572173	CCc1c(F)cc2[nH]ncc2c1-c1nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c1F)N1CCCOC[C@H]1CO2			785345	US12466840, Example Ex-2	GTPase KRas [G12D]	Homo sapiens		 0.650							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1006&target=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785345&enzyme=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JHL,7NY8,6YXW,6MQN,7W5R,7C41,7C40,6YR8,5UK9,5UFE,7RSE,7RSC,6W4E,9KFL,4TQ9,5OCG,4DSU,4DST,4DSO,4DSN,6W4F,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8QVU,5WPM,5WLB,6P0Z,5VQ0,5VPZ,5VPY,5VPI,5VP7,5V9O,5V9L,5V71,5KYK,6M9W,5WHB,5WHA,9BG5,6GOE,8EPW,8EBZ,7KFZ,6XGV,6OB3,7RP3,8AFC,9UOH,8X6R,8V3A,8V39	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572174	CCc1c(F)cc2[nH]ncc2c1-c1nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c1F)N1CCCOC[C@H]1CO2			785345	US12466840, Example Ex-2	GTPase KRas [G12V]	Homo sapiens		 1.30							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1398&target=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785345&enzyme=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8PI0,7NY8,6YXW,6MQN,5V9O,5V9L,5V71,5KYK,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GJ8,9C41,5UK9,5UFE,6YR8,6WS4,9C43,5UFQ,7ROV,9C3Q,7RP3,8STN,6P0Z,5WHE,5WHD,7F0W,7EYX,9C3R,7XKJ,9RKC,9P45,9P44,9GBJ,9C40,8AZY,6ZL5,6GJ5,4EPR,6M9W,8AFC,9BG5,9U99,9U90,9U8Z,9U8U,8FMK,8FMJ,11QE,8EPW,8EBZ,7KFZ,6XGV,6OB3,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9E9I,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3N,9C3M,9U95,9U8W,9U97,9U8Y,9U8V	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10		small monomeric GTPase	L7RSL8_HUMAN	L7RSL8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1572175	CCc1c(F)cc2[nH]ncc2c1-c1nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c1F)N1CCCOC[C@H]1CO2			785345	US12466840, Example Ex-2	GTPase KRas	Homo sapiens		 1.10							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006227&target=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785345&enzyme=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7VVB,8T75,8T74,8T72,8T71,6FA1,6GOM,6FA3,6ASA,6FA2,6GQX,6GQT,6GQY,6GQW,6GJ8,4TQA,7W5R,7C41,7C40,6BOF,6MBQ,9KFL,7ROV,6O36,5VQ0,5VPZ,5VPY,5VPI,5VP7,6E6G,6E6F,5UFQ,4TQ9,6O46,9C41,6WS4,9C3Q,8G4F,6H47,6H46,5V9O,5V9L,5V71,5O2T,5O2S,5MLB,5MLA,5KYK,8STN,5WPM,5WLB,7F0W,7EYX,9C43,8UN4,7XKJ,8FMK,8FMJ,9C40,9RKC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572176	CCc1c(F)cc2[nH]ncc2c1-c1nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c1F)N1CCCOC[C@H]1CO2			785345	US12466840, Example Ex-2	GTPase KRas [G12C]	Homo sapiens		 3.20							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=864&target=GTPase+KRas+%5BG12C%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785345&enzyme=GTPase+KRas+%5BG12C%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JGD,7W5R,7C41,7C40,9KFL,4TQ9,5WPM,5WLB,7NY8,6YXW,6MQN,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,5VQ0,5VPZ,5VPY,5VPI,5VP7,6YR8,6GJ8,5UK9,5UFE,5WHB,5WHA,6GOE,5UFQ,6WS4,9C41,9C3Q,6P0Z,7ROV,9C43,7F0W,7EYX,6M9W,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,8STN,7XKJ,8FMK,8FMJ,9BG5,9C40,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3R,9U99,9U90	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572177	CCc1c(F)cc2[nH]ncc2c1-c1nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c1F)N1CCCOC[C@H]1CO2			785345	US12466840, Example Ex-2	GTPase KRas [G13D]	Homo sapiens		 1.000							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1403&target=GTPase+KRas+%5BG13D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785345&enzyme=GTPase+KRas+%5BG13D%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGDVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8CPR,8BLR,8UN3,8UN5,7NY8,6YXW,6MQN,6YR8,5UK9,5UFE,8TBJ,9BHQ,8TBN,9E3S,7TLK,9BHO,6P0Z,6M9W,9USB,9U5T,9CTB,9CTA,9CT9,9CT8,9CT7,9L6F,9L6A,9E5F,9E5D,9BI1,9BGH,8WB1,8TXH,8TXG,8TXE,8R7X,8R7W,7EWB,7EWA,7EW9,7ACQ,7ACH,7ACF,7ACA,6ZLI,6QUX,6QUW,6QUV,6GJ7,6GJ6,9BGC,8TBH,5XCO,9RKN,9RKJ,9RKE,6CU6,4QL3,6QUU,9BGA,9BFV,8TBK,8G9P,8TY9,8TY8,8TY2,8TXK,8TXJ,8TVK,7MDP,5USJ,5US4,9PIZ,9N9N,9BI2,9BHP,7A47,7A1Y,7A1X,7A1W,4NMM,4LDJ,4L8G,9KPN,9KPM,8G47,8G42,9PZY	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572178	CCc1c(F)cc2[nH]ncc2c1-c1nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c1F)N1CCCOC[C@H]1CO2			785345	US12466840, Example Ex-2	GTPase HRas	Homo sapiens		 2743							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1541&target=GTPase+HRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785345&enzyme=GTPase+HRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS	4Q21,6Q21,1Q21,1IOZ,1AA9,7VV9,6AMB,6KYH,7L0F,6AXG,5E95,8BEA,8BE9,8BE8,8BE7,8BE6,8WWC,8OSO,8OSN,8OSM,8CNN,8CNJ,8BWG,8BOS,7OGC,7OGB,7OGA,7OG9,5P21,4RSG,4NYM,4NYJ,4G0N,4DLW,4DLU,4DLT,4DLS,3TGP,3RSO,3RSL,3RS7,3RS5,3RS4,3RS3,3RS2,3RS0,3RRZ,3RRY,3LBN,3LBI,3LBH,3L8Z,3L8Y,3KUD,3K8Y,2RGE,1XD2,1WQ1,1QRA,1P2V,1P2U,1P2T,1P2S,1NVW,1NVV,1K8R,1GNR,1GNQ,1GNP,1CTQ,1CRR,1CRQ,1CRP,1BKD,121P,8TBG,6ZL3,6V9O,6V9N,6V9M,6V9L,6V9J,6V9F,6V94,6D5W,6D5V,6D5M,6D5L,6D5J,6D5H,6D5G,6D5E,6D59,6D56,6D55,6CUR,6CUP,6CUO,6BVM,6BVL,6BVK,6BVJ,6BVI,5WFR,5WFQ,5WFP,5WFO,4NYI,5WDO,5B30,5B2Z,4EFL,4US2,4US1,4US0,4URZ,4URY,4URX,4URW,4URV,4URU	GTPase HRas	RASH_HUMAN	P01112	B5BUA0 Q14080 Q6FHV9 Q9BR65 Q9UCE2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572179	CCc1c(F)cc2[nH]ncc2c1-c1nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c1F)N1CCCOC[C@H]1CO2			785345	US12466840, Example Ex-2	GTPase NRas	Homo sapiens		 7022							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006303&target=GTPase+NRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785345&enzyme=GTPase+NRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQGCMGLPCVVM	8TBI,3CON,8VM2,6ZIR,6ZIO,9BG0,5UHV,6WGH,4Q21,6MQT,6E6P,6E6C,6DZH,1AGP,421P,6ZJ0,821P,1PLL,1PLJ,1JAI,1CLU,7L0G,8TLR,4L9W,4L9S,1PLK,1JAH	GTPase NRas	RASN_HUMAN	P01111	Q14971 Q15104 Q15282																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572180	CCc1c(F)cc2[nH]ncc2c1-c1nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c1F)N1CCCOC[C@H]1CO2			785345	US12466840, Example Ex-2	GTPase KRas [G12A]	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2069&target=GTPase+KRas+%5BG12A%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785345&enzyme=GTPase+KRas+%5BG12A%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAAGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6MQN,7W5R,7C41,7C40,7NY8,6YXW,9KFL,4TQ9,6YR8,5WPM,5WLB,5UK9,5UFE,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,5V9O,5V9L,5V71,5KYK,6GJ8,5WHB,5WHA,6GOE,9C41,6M9W,7ROV,6WS4,5UFQ,6P0Z,9C43,9BG5,9C3Q,8STN,8EPW,8EBZ,7KFZ,6XGV,6OB3,7F0W,7EYX,7RP3,9C40,7XKJ,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,9C3R,9U99,9U90,8FMK,8FMJ,11QE,9U8Z,9U8U,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,8AFC,9C3K,9C3V,9E9I,9U8X,9U8T,9C3Z,9U8V,9C3N,9C3M,9U95,9U8W,9U97,9U8Y	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572181	CCc1c(F)cc2[nH]ncc2c1-c1nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c1F)N1CCCOC[C@H]1CO2			785345	US12466840, Example Ex-2	GTPase KRas [G12S]	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1374&target=GTPase+KRas+%5BG12S%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785345&enzyme=GTPase+KRas+%5BG12S%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGASGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6MQN,7NY8,6YXW,7W5R,7C41,7C40,6GJ8,9KFL,4TQ9,6YR8,5UK9,5UFE,9C41,5VQ0,5VPZ,5VPY,5VPI,5VP7,5UFQ,5V9O,5V9L,5V71,5KYK,6WS4,7ROV,5WPM,5WLB,9C3Q,9C43,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8STN,7F0W,7EYX,6P0Z,5WHB,5WHA,6M9W,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,6GOE,9C3R,9C40,7XKJ,9BG5,8FMK,8FMJ,11QE,9U99,9U90,7RP3,9U8Z,9U8U,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3M,9C3N,9U8V,8AFC,9U95,9U8W,9E9I,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9U97,9U8Y	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572182	CCc1c(F)cc2[nH]ncc2c1-c1nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c1F)N1CCCOC[C@H]1CO2			785345	US12466840, Example Ex-2	GTPase KRas [G12R]	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2068&target=GTPase+KRas+%5BG12R%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785345&enzyme=GTPase+KRas+%5BG12R%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGARGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7W5R,7C41,7C40,6MQN,7NY8,6YXW,9KFL,6GJ8,4TQ9,9C41,6WS4,5UFQ,5UK9,5UFE,6YR8,9C3Q,7ROV,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,9C43,5WPM,5WLB,8STN,7F0W,7EYX,5WHB,5WHA,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GOE,5V9O,5V9L,5V71,5KYK,6M9W,9C40,7XKJ,6P0Z,9BG5,9C3R,9U8Z,9U8U,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,9U99,9U90,11QE,8FMK,8FMJ,9C3K,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3V,9U8X,9U8T,7RP3,9C3Z,9U95,9U8W,9U8V,9C3N,9C3M,9U97,9U8Y,8AFC,9E9I,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572183	CCc1c(F)cc2[nH]ncc2c1-c1nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c1F)N1CCCOC[C@H]1CO2			785345	US12466840, Example Ex-2	GTPase KRas [Q61H]	Homo sapiens		 1.20							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1404&target=GTPase+KRas+%5BQ61H%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785345&enzyme=GTPase+KRas+%5BQ61H%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGHEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6GQW,6MQN,7NY8,6YXW,8TBJ,5UK9,5UFE,6YR8,8TBN,9E3S,6P0Z,7TLK,9BHQ,9BHO,6M9W,9CTB,9CTA,9CT9,9CT8,9CT7,9BG5,9USB,9U5T,5XCO,9L6F,9L6A,9E5F,9E5D,9BI1,9BGH,8WB1,8TXH,8TXG,8TXE,8R7X,8R7W,8EPW,8EBZ,7KFZ,7EWB,7EWA,7EW9,7ACQ,7ACH,7ACF,7ACA,6ZLI,6XGV,6QUX,6QUW,6QUV,6OB3,6GJ7,6GJ6,9BGC,8TBH,6QUU,9BGA,9BFV,8TBK,8G9P,9RKN,9RKJ,9RKE,6CU6,4QL3,9PIZ,8TY9,8TY8,8TY2,8TXK,8TXJ,8TVK,7MDP,5USJ,5US4,9BI2,9BHP,7A47,7A1Y,7A1X,7A1W,4NMM,4LDJ,4L8G,9N9N,9KPN,9KPM,8G47,8G42,9PZY	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572184	Fc1c(-c2c(C3CC3)c(Cl)cc3[nH]ncc23)nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc13)N1CCCOC[C@H]1CO2	InChI=1S/C31H32ClF2N7O3/c32-20-9-21-19(11-35-39-21)23(22(20)16-3-4-16)26-25(34)27-24-28(41-7-2-8-42-13-18(41)14-43-29(24)36-26)38-30(37-27)44-15-31-5-1-6-40(31)12-17(33)10-31/h9,11,16-18H,1-8,10,12-15H2,(H,35,39)	FWEYEIDZVXMPKP-UHFFFAOYSA-N	717613	(General Method A): (8aS)-5-(6-chloro-5-cyclopropyl-1H-indazol-4-yl)-4-fluoro-2-{[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}-8a,9,12,13-tetrahydro-8H,11H-7,10-dioxa-1,3,6,13a-tetraazanaphtho[1,8-ab]heptalene::US20250034173, Example 1::US12466840, Example Ex-3	GTPase KRas [G12D]	Homo sapiens		 1.30							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=717613	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1006&target=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=717613&enzyme=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search			172194330	513837665							1	MTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JHL,7NY8,6YXW,6MQN,7W5R,7C41,7C40,6YR8,5UK9,5UFE,7RSE,7RSC,6W4E,9KFL,4TQ9,5OCG,4DSU,4DST,4DSO,4DSN,6W4F,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8QVU,5WPM,5WLB,6P0Z,5VQ0,5VPZ,5VPY,5VPI,5VP7,5V9O,5V9L,5V71,5KYK,6M9W,5WHB,5WHA,9BG5,6GOE,8EPW,8EBZ,7KFZ,6XGV,6OB3,7RP3,8AFC,9UOH,8X6R,8V3A,8V39	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572185	Fc1c(-c2c(C3CC3)c(Cl)cc3[nH]ncc23)nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc13)N1CCCOC[C@H]1CO2	InChI=1S/C31H32ClF2N7O3/c32-20-9-21-19(11-35-39-21)23(22(20)16-3-4-16)26-25(34)27-24-28(41-7-2-8-42-13-18(41)14-43-29(24)36-26)38-30(37-27)44-15-31-5-1-6-40(31)12-17(33)10-31/h9,11,16-18H,1-8,10,12-15H2,(H,35,39)	FWEYEIDZVXMPKP-UHFFFAOYSA-N	717613	(General Method A): (8aS)-5-(6-chloro-5-cyclopropyl-1H-indazol-4-yl)-4-fluoro-2-{[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}-8a,9,12,13-tetrahydro-8H,11H-7,10-dioxa-1,3,6,13a-tetraazanaphtho[1,8-ab]heptalene::US20250034173, Example 1::US12466840, Example Ex-3	GTPase KRas [G12V]	Homo sapiens		 3.00							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=717613	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1398&target=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=717613&enzyme=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search			172194330	513837665							1	MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8PI0,7NY8,6YXW,6MQN,5V9O,5V9L,5V71,5KYK,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GJ8,9C41,5UK9,5UFE,6YR8,6WS4,9C43,5UFQ,7ROV,9C3Q,7RP3,8STN,6P0Z,5WHE,5WHD,7F0W,7EYX,9C3R,7XKJ,9RKC,9P45,9P44,9GBJ,9C40,8AZY,6ZL5,6GJ5,4EPR,6M9W,8AFC,9BG5,9U99,9U90,9U8Z,9U8U,8FMK,8FMJ,11QE,8EPW,8EBZ,7KFZ,6XGV,6OB3,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9E9I,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3N,9C3M,9U95,9U8W,9U97,9U8Y,9U8V	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10		small monomeric GTPase	L7RSL8_HUMAN	L7RSL8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1572186	Fc1c(-c2c(C3CC3)c(Cl)cc3[nH]ncc23)nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc13)N1CCCOC[C@H]1CO2	InChI=1S/C31H32ClF2N7O3/c32-20-9-21-19(11-35-39-21)23(22(20)16-3-4-16)26-25(34)27-24-28(41-7-2-8-42-13-18(41)14-43-29(24)36-26)38-30(37-27)44-15-31-5-1-6-40(31)12-17(33)10-31/h9,11,16-18H,1-8,10,12-15H2,(H,35,39)	FWEYEIDZVXMPKP-UHFFFAOYSA-N	717613	(General Method A): (8aS)-5-(6-chloro-5-cyclopropyl-1H-indazol-4-yl)-4-fluoro-2-{[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}-8a,9,12,13-tetrahydro-8H,11H-7,10-dioxa-1,3,6,13a-tetraazanaphtho[1,8-ab]heptalene::US20250034173, Example 1::US12466840, Example Ex-3	GTPase KRas	Homo sapiens		 2.50							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=717613	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006227&target=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=717613&enzyme=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search			172194330	513837665							1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7VVB,8T75,8T74,8T72,8T71,6FA1,6GOM,6FA3,6ASA,6FA2,6GQX,6GQT,6GQY,6GQW,6GJ8,4TQA,7W5R,7C41,7C40,6BOF,6MBQ,9KFL,7ROV,6O36,5VQ0,5VPZ,5VPY,5VPI,5VP7,6E6G,6E6F,5UFQ,4TQ9,6O46,9C41,6WS4,9C3Q,8G4F,6H47,6H46,5V9O,5V9L,5V71,5O2T,5O2S,5MLB,5MLA,5KYK,8STN,5WPM,5WLB,7F0W,7EYX,9C43,8UN4,7XKJ,8FMK,8FMJ,9C40,9RKC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572187	CCc1c(F)ccc2cc3[nH]ncc3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785347	US12466840, Example Ex-4	GTPase KRas [G12D]	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1006&target=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785347&enzyme=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JHL,7NY8,6YXW,6MQN,7W5R,7C41,7C40,6YR8,5UK9,5UFE,7RSE,7RSC,6W4E,9KFL,4TQ9,5OCG,4DSU,4DST,4DSO,4DSN,6W4F,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8QVU,5WPM,5WLB,6P0Z,5VQ0,5VPZ,5VPY,5VPI,5VP7,5V9O,5V9L,5V71,5KYK,6M9W,5WHB,5WHA,9BG5,6GOE,8EPW,8EBZ,7KFZ,6XGV,6OB3,7RP3,8AFC,9UOH,8X6R,8V3A,8V39	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572188	CCc1c(F)ccc2cc3[nH]ncc3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785347	US12466840, Example Ex-4	GTPase KRas [G12V]	Homo sapiens		 0.830							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1398&target=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785347&enzyme=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8PI0,7NY8,6YXW,6MQN,5V9O,5V9L,5V71,5KYK,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GJ8,9C41,5UK9,5UFE,6YR8,6WS4,9C43,5UFQ,7ROV,9C3Q,7RP3,8STN,6P0Z,5WHE,5WHD,7F0W,7EYX,9C3R,7XKJ,9RKC,9P45,9P44,9GBJ,9C40,8AZY,6ZL5,6GJ5,4EPR,6M9W,8AFC,9BG5,9U99,9U90,9U8Z,9U8U,8FMK,8FMJ,11QE,8EPW,8EBZ,7KFZ,6XGV,6OB3,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9E9I,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3N,9C3M,9U95,9U8W,9U97,9U8Y,9U8V	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10		small monomeric GTPase	L7RSL8_HUMAN	L7RSL8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1572189	CCc1c(F)ccc2cc3[nH]ncc3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785347	US12466840, Example Ex-4	GTPase KRas	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006227&target=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785347&enzyme=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7VVB,8T75,8T74,8T72,8T71,6FA1,6GOM,6FA3,6ASA,6FA2,6GQX,6GQT,6GQY,6GQW,6GJ8,4TQA,7W5R,7C41,7C40,6BOF,6MBQ,9KFL,7ROV,6O36,5VQ0,5VPZ,5VPY,5VPI,5VP7,6E6G,6E6F,5UFQ,4TQ9,6O46,9C41,6WS4,9C3Q,8G4F,6H47,6H46,5V9O,5V9L,5V71,5O2T,5O2S,5MLB,5MLA,5KYK,8STN,5WPM,5WLB,7F0W,7EYX,9C43,8UN4,7XKJ,8FMK,8FMJ,9C40,9RKC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572190	CCc1c(F)ccc2cc3[nH]ncc3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785347	US12466840, Example Ex-4	GTPase KRas [G12C]	Homo sapiens		 2.90							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=864&target=GTPase+KRas+%5BG12C%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785347&enzyme=GTPase+KRas+%5BG12C%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JGD,7W5R,7C41,7C40,9KFL,4TQ9,5WPM,5WLB,7NY8,6YXW,6MQN,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,5VQ0,5VPZ,5VPY,5VPI,5VP7,6YR8,6GJ8,5UK9,5UFE,5WHB,5WHA,6GOE,5UFQ,6WS4,9C41,9C3Q,6P0Z,7ROV,9C43,7F0W,7EYX,6M9W,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,8STN,7XKJ,8FMK,8FMJ,9BG5,9C40,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3R,9U99,9U90	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572191	CCc1c(F)ccc2cc3[nH]ncc3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785347	US12466840, Example Ex-4	GTPase KRas [G13D]	Homo sapiens		 0.890							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1403&target=GTPase+KRas+%5BG13D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785347&enzyme=GTPase+KRas+%5BG13D%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGDVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8CPR,8BLR,8UN3,8UN5,7NY8,6YXW,6MQN,6YR8,5UK9,5UFE,8TBJ,9BHQ,8TBN,9E3S,7TLK,9BHO,6P0Z,6M9W,9USB,9U5T,9CTB,9CTA,9CT9,9CT8,9CT7,9L6F,9L6A,9E5F,9E5D,9BI1,9BGH,8WB1,8TXH,8TXG,8TXE,8R7X,8R7W,7EWB,7EWA,7EW9,7ACQ,7ACH,7ACF,7ACA,6ZLI,6QUX,6QUW,6QUV,6GJ7,6GJ6,9BGC,8TBH,5XCO,9RKN,9RKJ,9RKE,6CU6,4QL3,6QUU,9BGA,9BFV,8TBK,8G9P,8TY9,8TY8,8TY2,8TXK,8TXJ,8TVK,7MDP,5USJ,5US4,9PIZ,9N9N,9BI2,9BHP,7A47,7A1Y,7A1X,7A1W,4NMM,4LDJ,4L8G,9KPN,9KPM,8G47,8G42,9PZY	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572192	CCc1c(F)ccc2cc3[nH]ncc3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785347	US12466840, Example Ex-4	GTPase HRas	Homo sapiens		 1275							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1541&target=GTPase+HRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785347&enzyme=GTPase+HRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS	4Q21,6Q21,1Q21,1IOZ,1AA9,7VV9,6AMB,6KYH,7L0F,6AXG,5E95,8BEA,8BE9,8BE8,8BE7,8BE6,8WWC,8OSO,8OSN,8OSM,8CNN,8CNJ,8BWG,8BOS,7OGC,7OGB,7OGA,7OG9,5P21,4RSG,4NYM,4NYJ,4G0N,4DLW,4DLU,4DLT,4DLS,3TGP,3RSO,3RSL,3RS7,3RS5,3RS4,3RS3,3RS2,3RS0,3RRZ,3RRY,3LBN,3LBI,3LBH,3L8Z,3L8Y,3KUD,3K8Y,2RGE,1XD2,1WQ1,1QRA,1P2V,1P2U,1P2T,1P2S,1NVW,1NVV,1K8R,1GNR,1GNQ,1GNP,1CTQ,1CRR,1CRQ,1CRP,1BKD,121P,8TBG,6ZL3,6V9O,6V9N,6V9M,6V9L,6V9J,6V9F,6V94,6D5W,6D5V,6D5M,6D5L,6D5J,6D5H,6D5G,6D5E,6D59,6D56,6D55,6CUR,6CUP,6CUO,6BVM,6BVL,6BVK,6BVJ,6BVI,5WFR,5WFQ,5WFP,5WFO,4NYI,5WDO,5B30,5B2Z,4EFL,4US2,4US1,4US0,4URZ,4URY,4URX,4URW,4URV,4URU	GTPase HRas	RASH_HUMAN	P01112	B5BUA0 Q14080 Q6FHV9 Q9BR65 Q9UCE2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572193	CCc1c(F)ccc2cc3[nH]ncc3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785347	US12466840, Example Ex-4	GTPase NRas	Homo sapiens		 2818							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006303&target=GTPase+NRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785347&enzyme=GTPase+NRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQGCMGLPCVVM	8TBI,3CON,8VM2,6ZIR,6ZIO,9BG0,5UHV,6WGH,4Q21,6MQT,6E6P,6E6C,6DZH,1AGP,421P,6ZJ0,821P,1PLL,1PLJ,1JAI,1CLU,7L0G,8TLR,4L9W,4L9S,1PLK,1JAH	GTPase NRas	RASN_HUMAN	P01111	Q14971 Q15104 Q15282																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572194	CCc1c(F)ccc2cc3[nH]ncc3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785347	US12466840, Example Ex-4	GTPase KRas [G12A]	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2069&target=GTPase+KRas+%5BG12A%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785347&enzyme=GTPase+KRas+%5BG12A%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAAGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6MQN,7W5R,7C41,7C40,7NY8,6YXW,9KFL,4TQ9,6YR8,5WPM,5WLB,5UK9,5UFE,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,5V9O,5V9L,5V71,5KYK,6GJ8,5WHB,5WHA,6GOE,9C41,6M9W,7ROV,6WS4,5UFQ,6P0Z,9C43,9BG5,9C3Q,8STN,8EPW,8EBZ,7KFZ,6XGV,6OB3,7F0W,7EYX,7RP3,9C40,7XKJ,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,9C3R,9U99,9U90,8FMK,8FMJ,11QE,9U8Z,9U8U,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,8AFC,9C3K,9C3V,9E9I,9U8X,9U8T,9C3Z,9U8V,9C3N,9C3M,9U95,9U8W,9U97,9U8Y	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572195	CCc1c(F)ccc2cc3[nH]ncc3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785347	US12466840, Example Ex-4	GTPase KRas [G12S]	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1374&target=GTPase+KRas+%5BG12S%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785347&enzyme=GTPase+KRas+%5BG12S%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGASGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6MQN,7NY8,6YXW,7W5R,7C41,7C40,6GJ8,9KFL,4TQ9,6YR8,5UK9,5UFE,9C41,5VQ0,5VPZ,5VPY,5VPI,5VP7,5UFQ,5V9O,5V9L,5V71,5KYK,6WS4,7ROV,5WPM,5WLB,9C3Q,9C43,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8STN,7F0W,7EYX,6P0Z,5WHB,5WHA,6M9W,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,6GOE,9C3R,9C40,7XKJ,9BG5,8FMK,8FMJ,11QE,9U99,9U90,7RP3,9U8Z,9U8U,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3M,9C3N,9U8V,8AFC,9U95,9U8W,9E9I,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9U97,9U8Y	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572196	CCc1c(F)ccc2cc3[nH]ncc3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785347	US12466840, Example Ex-4	GTPase KRas [G12R]	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2068&target=GTPase+KRas+%5BG12R%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785347&enzyme=GTPase+KRas+%5BG12R%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGARGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7W5R,7C41,7C40,6MQN,7NY8,6YXW,9KFL,6GJ8,4TQ9,9C41,6WS4,5UFQ,5UK9,5UFE,6YR8,9C3Q,7ROV,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,9C43,5WPM,5WLB,8STN,7F0W,7EYX,5WHB,5WHA,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GOE,5V9O,5V9L,5V71,5KYK,6M9W,9C40,7XKJ,6P0Z,9BG5,9C3R,9U8Z,9U8U,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,9U99,9U90,11QE,8FMK,8FMJ,9C3K,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3V,9U8X,9U8T,7RP3,9C3Z,9U95,9U8W,9U8V,9C3N,9C3M,9U97,9U8Y,8AFC,9E9I,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572197	CCc1c(F)ccc2cc3[nH]ncc3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785347	US12466840, Example Ex-4	GTPase KRas [Q61H]	Homo sapiens		 1.000							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1404&target=GTPase+KRas+%5BQ61H%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785347&enzyme=GTPase+KRas+%5BQ61H%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGHEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6GQW,6MQN,7NY8,6YXW,8TBJ,5UK9,5UFE,6YR8,8TBN,9E3S,6P0Z,7TLK,9BHQ,9BHO,6M9W,9CTB,9CTA,9CT9,9CT8,9CT7,9BG5,9USB,9U5T,5XCO,9L6F,9L6A,9E5F,9E5D,9BI1,9BGH,8WB1,8TXH,8TXG,8TXE,8R7X,8R7W,8EPW,8EBZ,7KFZ,7EWB,7EWA,7EW9,7ACQ,7ACH,7ACF,7ACA,6ZLI,6XGV,6QUX,6QUW,6QUV,6OB3,6GJ7,6GJ6,9BGC,8TBH,6QUU,9BGA,9BFV,8TBK,8G9P,9RKN,9RKJ,9RKE,6CU6,4QL3,9PIZ,8TY9,8TY8,8TY2,8TXK,8TXJ,8TVK,7MDP,5USJ,5US4,9BI2,9BHP,7A47,7A1Y,7A1X,7A1W,4NMM,4LDJ,4L8G,9N9N,9KPN,9KPM,8G47,8G42,9PZY	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572198	F/C=C1\CN2CCC[C@@]2(COc2nc3c4c(nc(-c5c(C6(F)CC6)c(Cl)cc6[nH]ncc56)c(F)c4n2)OC[C@@H]2COCCCN32)C1			785348	US12466840, Example Ex-5	GTPase KRas [G12D]	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1006&target=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785348&enzyme=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JHL,7NY8,6YXW,6MQN,7W5R,7C41,7C40,6YR8,5UK9,5UFE,7RSE,7RSC,6W4E,9KFL,4TQ9,5OCG,4DSU,4DST,4DSO,4DSN,6W4F,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8QVU,5WPM,5WLB,6P0Z,5VQ0,5VPZ,5VPY,5VPI,5VP7,5V9O,5V9L,5V71,5KYK,6M9W,5WHB,5WHA,9BG5,6GOE,8EPW,8EBZ,7KFZ,6XGV,6OB3,7RP3,8AFC,9UOH,8X6R,8V3A,8V39	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572199	F/C=C1\CN2CCC[C@@]2(COc2nc3c4c(nc(-c5c(C6(F)CC6)c(Cl)cc6[nH]ncc56)c(F)c4n2)OC[C@@H]2COCCCN32)C1			785348	US12466840, Example Ex-5	GTPase KRas [G12V]	Homo sapiens		 0.980							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1398&target=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785348&enzyme=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8PI0,7NY8,6YXW,6MQN,5V9O,5V9L,5V71,5KYK,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GJ8,9C41,5UK9,5UFE,6YR8,6WS4,9C43,5UFQ,7ROV,9C3Q,7RP3,8STN,6P0Z,5WHE,5WHD,7F0W,7EYX,9C3R,7XKJ,9RKC,9P45,9P44,9GBJ,9C40,8AZY,6ZL5,6GJ5,4EPR,6M9W,8AFC,9BG5,9U99,9U90,9U8Z,9U8U,8FMK,8FMJ,11QE,8EPW,8EBZ,7KFZ,6XGV,6OB3,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9E9I,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3N,9C3M,9U95,9U8W,9U97,9U8Y,9U8V	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10		small monomeric GTPase	L7RSL8_HUMAN	L7RSL8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1572200	F/C=C1\CN2CCC[C@@]2(COc2nc3c4c(nc(-c5c(C6(F)CC6)c(Cl)cc6[nH]ncc56)c(F)c4n2)OC[C@@H]2COCCCN32)C1			785348	US12466840, Example Ex-5	GTPase KRas	Homo sapiens		<0.690							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006227&target=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785348&enzyme=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7VVB,8T75,8T74,8T72,8T71,6FA1,6GOM,6FA3,6ASA,6FA2,6GQX,6GQT,6GQY,6GQW,6GJ8,4TQA,7W5R,7C41,7C40,6BOF,6MBQ,9KFL,7ROV,6O36,5VQ0,5VPZ,5VPY,5VPI,5VP7,6E6G,6E6F,5UFQ,4TQ9,6O46,9C41,6WS4,9C3Q,8G4F,6H47,6H46,5V9O,5V9L,5V71,5O2T,5O2S,5MLB,5MLA,5KYK,8STN,5WPM,5WLB,7F0W,7EYX,9C43,8UN4,7XKJ,8FMK,8FMJ,9C40,9RKC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572201	F/C=C1\CN2CCC[C@@]2(COc2nc3c4c(nc(-c5c(C6(F)CC6)c(Cl)cc6[nH]ncc56)c(F)c4n2)OC[C@@H]2COCCCN32)C1			785348	US12466840, Example Ex-5	GTPase KRas [G12C]	Homo sapiens		 3.30							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=864&target=GTPase+KRas+%5BG12C%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785348&enzyme=GTPase+KRas+%5BG12C%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JGD,7W5R,7C41,7C40,9KFL,4TQ9,5WPM,5WLB,7NY8,6YXW,6MQN,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,5VQ0,5VPZ,5VPY,5VPI,5VP7,6YR8,6GJ8,5UK9,5UFE,5WHB,5WHA,6GOE,5UFQ,6WS4,9C41,9C3Q,6P0Z,7ROV,9C43,7F0W,7EYX,6M9W,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,8STN,7XKJ,8FMK,8FMJ,9BG5,9C40,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3R,9U99,9U90	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572202	F/C=C1\CN2CCC[C@@]2(COc2nc3c4c(nc(-c5c(C6(F)CC6)c(Cl)cc6[nH]ncc56)c(F)c4n2)OC[C@@H]2COCCCN32)C1			785348	US12466840, Example Ex-5	GTPase KRas [G13D]	Homo sapiens		 1.20							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1403&target=GTPase+KRas+%5BG13D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785348&enzyme=GTPase+KRas+%5BG13D%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGDVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8CPR,8BLR,8UN3,8UN5,7NY8,6YXW,6MQN,6YR8,5UK9,5UFE,8TBJ,9BHQ,8TBN,9E3S,7TLK,9BHO,6P0Z,6M9W,9USB,9U5T,9CTB,9CTA,9CT9,9CT8,9CT7,9L6F,9L6A,9E5F,9E5D,9BI1,9BGH,8WB1,8TXH,8TXG,8TXE,8R7X,8R7W,7EWB,7EWA,7EW9,7ACQ,7ACH,7ACF,7ACA,6ZLI,6QUX,6QUW,6QUV,6GJ7,6GJ6,9BGC,8TBH,5XCO,9RKN,9RKJ,9RKE,6CU6,4QL3,6QUU,9BGA,9BFV,8TBK,8G9P,8TY9,8TY8,8TY2,8TXK,8TXJ,8TVK,7MDP,5USJ,5US4,9PIZ,9N9N,9BI2,9BHP,7A47,7A1Y,7A1X,7A1W,4NMM,4LDJ,4L8G,9KPN,9KPM,8G47,8G42,9PZY	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572203	F/C=C1\CN2CCC[C@@]2(COc2nc3c4c(nc(-c5c(C6(F)CC6)c(Cl)cc6[nH]ncc56)c(F)c4n2)OC[C@@H]2COCCCN32)C1			785348	US12466840, Example Ex-5	GTPase HRas	Homo sapiens		 4684							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1541&target=GTPase+HRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785348&enzyme=GTPase+HRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS	4Q21,6Q21,1Q21,1IOZ,1AA9,7VV9,6AMB,6KYH,7L0F,6AXG,5E95,8BEA,8BE9,8BE8,8BE7,8BE6,8WWC,8OSO,8OSN,8OSM,8CNN,8CNJ,8BWG,8BOS,7OGC,7OGB,7OGA,7OG9,5P21,4RSG,4NYM,4NYJ,4G0N,4DLW,4DLU,4DLT,4DLS,3TGP,3RSO,3RSL,3RS7,3RS5,3RS4,3RS3,3RS2,3RS0,3RRZ,3RRY,3LBN,3LBI,3LBH,3L8Z,3L8Y,3KUD,3K8Y,2RGE,1XD2,1WQ1,1QRA,1P2V,1P2U,1P2T,1P2S,1NVW,1NVV,1K8R,1GNR,1GNQ,1GNP,1CTQ,1CRR,1CRQ,1CRP,1BKD,121P,8TBG,6ZL3,6V9O,6V9N,6V9M,6V9L,6V9J,6V9F,6V94,6D5W,6D5V,6D5M,6D5L,6D5J,6D5H,6D5G,6D5E,6D59,6D56,6D55,6CUR,6CUP,6CUO,6BVM,6BVL,6BVK,6BVJ,6BVI,5WFR,5WFQ,5WFP,5WFO,4NYI,5WDO,5B30,5B2Z,4EFL,4US2,4US1,4US0,4URZ,4URY,4URX,4URW,4URV,4URU	GTPase HRas	RASH_HUMAN	P01112	B5BUA0 Q14080 Q6FHV9 Q9BR65 Q9UCE2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572204	F/C=C1\CN2CCC[C@@]2(COc2nc3c4c(nc(-c5c(C6(F)CC6)c(Cl)cc6[nH]ncc56)c(F)c4n2)OC[C@@H]2COCCCN32)C1			785348	US12466840, Example Ex-5	GTPase NRas	Homo sapiens		>11060							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006303&target=GTPase+NRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785348&enzyme=GTPase+NRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQGCMGLPCVVM	8TBI,3CON,8VM2,6ZIR,6ZIO,9BG0,5UHV,6WGH,4Q21,6MQT,6E6P,6E6C,6DZH,1AGP,421P,6ZJ0,821P,1PLL,1PLJ,1JAI,1CLU,7L0G,8TLR,4L9W,4L9S,1PLK,1JAH	GTPase NRas	RASN_HUMAN	P01111	Q14971 Q15104 Q15282																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572205	F/C=C1\CN2CCC[C@@]2(COc2nc3c4c(nc(-c5c(C6(F)CC6)c(Cl)cc6[nH]ncc56)c(F)c4n2)OC[C@@H]2COCCCN32)C1			785348	US12466840, Example Ex-5	GTPase KRas [G12A]	Homo sapiens		 0.830							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2069&target=GTPase+KRas+%5BG12A%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785348&enzyme=GTPase+KRas+%5BG12A%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAAGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6MQN,7W5R,7C41,7C40,7NY8,6YXW,9KFL,4TQ9,6YR8,5WPM,5WLB,5UK9,5UFE,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,5V9O,5V9L,5V71,5KYK,6GJ8,5WHB,5WHA,6GOE,9C41,6M9W,7ROV,6WS4,5UFQ,6P0Z,9C43,9BG5,9C3Q,8STN,8EPW,8EBZ,7KFZ,6XGV,6OB3,7F0W,7EYX,7RP3,9C40,7XKJ,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,9C3R,9U99,9U90,8FMK,8FMJ,11QE,9U8Z,9U8U,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,8AFC,9C3K,9C3V,9E9I,9U8X,9U8T,9C3Z,9U8V,9C3N,9C3M,9U95,9U8W,9U97,9U8Y	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572206	F/C=C1\CN2CCC[C@@]2(COc2nc3c4c(nc(-c5c(C6(F)CC6)c(Cl)cc6[nH]ncc56)c(F)c4n2)OC[C@@H]2COCCCN32)C1			785348	US12466840, Example Ex-5	GTPase KRas [G12S]	Homo sapiens		 0.770							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1374&target=GTPase+KRas+%5BG12S%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785348&enzyme=GTPase+KRas+%5BG12S%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGASGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6MQN,7NY8,6YXW,7W5R,7C41,7C40,6GJ8,9KFL,4TQ9,6YR8,5UK9,5UFE,9C41,5VQ0,5VPZ,5VPY,5VPI,5VP7,5UFQ,5V9O,5V9L,5V71,5KYK,6WS4,7ROV,5WPM,5WLB,9C3Q,9C43,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8STN,7F0W,7EYX,6P0Z,5WHB,5WHA,6M9W,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,6GOE,9C3R,9C40,7XKJ,9BG5,8FMK,8FMJ,11QE,9U99,9U90,7RP3,9U8Z,9U8U,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3M,9C3N,9U8V,8AFC,9U95,9U8W,9E9I,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9U97,9U8Y	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572207	F/C=C1\CN2CCC[C@@]2(COc2nc3c4c(nc(-c5c(C6(F)CC6)c(Cl)cc6[nH]ncc56)c(F)c4n2)OC[C@@H]2COCCCN32)C1			785348	US12466840, Example Ex-5	GTPase KRas [G12R]	Homo sapiens		 1.30							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2068&target=GTPase+KRas+%5BG12R%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785348&enzyme=GTPase+KRas+%5BG12R%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGARGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7W5R,7C41,7C40,6MQN,7NY8,6YXW,9KFL,6GJ8,4TQ9,9C41,6WS4,5UFQ,5UK9,5UFE,6YR8,9C3Q,7ROV,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,9C43,5WPM,5WLB,8STN,7F0W,7EYX,5WHB,5WHA,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GOE,5V9O,5V9L,5V71,5KYK,6M9W,9C40,7XKJ,6P0Z,9BG5,9C3R,9U8Z,9U8U,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,9U99,9U90,11QE,8FMK,8FMJ,9C3K,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3V,9U8X,9U8T,7RP3,9C3Z,9U95,9U8W,9U8V,9C3N,9C3M,9U97,9U8Y,8AFC,9E9I,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572208	F/C=C1\CN2CCC[C@@]2(COc2nc3c4c(nc(-c5c(C6(F)CC6)c(Cl)cc6[nH]ncc56)c(F)c4n2)OC[C@@H]2COCCCN32)C1			785348	US12466840, Example Ex-5	GTPase KRas [Q61H]	Homo sapiens		 0.970							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1404&target=GTPase+KRas+%5BQ61H%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785348&enzyme=GTPase+KRas+%5BQ61H%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGHEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6GQW,6MQN,7NY8,6YXW,8TBJ,5UK9,5UFE,6YR8,8TBN,9E3S,6P0Z,7TLK,9BHQ,9BHO,6M9W,9CTB,9CTA,9CT9,9CT8,9CT7,9BG5,9USB,9U5T,5XCO,9L6F,9L6A,9E5F,9E5D,9BI1,9BGH,8WB1,8TXH,8TXG,8TXE,8R7X,8R7W,8EPW,8EBZ,7KFZ,7EWB,7EWA,7EW9,7ACQ,7ACH,7ACF,7ACA,6ZLI,6XGV,6QUX,6QUW,6QUV,6OB3,6GJ7,6GJ6,9BGC,8TBH,6QUU,9BGA,9BFV,8TBK,8G9P,9RKN,9RKJ,9RKE,6CU6,4QL3,9PIZ,8TY9,8TY8,8TY2,8TXK,8TXJ,8TVK,7MDP,5USJ,5US4,9BI2,9BHP,7A47,7A1Y,7A1X,7A1W,4NMM,4LDJ,4L8G,9N9N,9KPN,9KPM,8G47,8G42,9PZY	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572209	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785349	US12466840, Example Ex-6	GTPase KRas [G12D]	Homo sapiens		 1.30							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1006&target=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785349&enzyme=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JHL,7NY8,6YXW,6MQN,7W5R,7C41,7C40,6YR8,5UK9,5UFE,7RSE,7RSC,6W4E,9KFL,4TQ9,5OCG,4DSU,4DST,4DSO,4DSN,6W4F,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8QVU,5WPM,5WLB,6P0Z,5VQ0,5VPZ,5VPY,5VPI,5VP7,5V9O,5V9L,5V71,5KYK,6M9W,5WHB,5WHA,9BG5,6GOE,8EPW,8EBZ,7KFZ,6XGV,6OB3,7RP3,8AFC,9UOH,8X6R,8V3A,8V39	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572210	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785349	US12466840, Example Ex-6	GTPase KRas [G12V]	Homo sapiens		 1.50							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1398&target=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785349&enzyme=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8PI0,7NY8,6YXW,6MQN,5V9O,5V9L,5V71,5KYK,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GJ8,9C41,5UK9,5UFE,6YR8,6WS4,9C43,5UFQ,7ROV,9C3Q,7RP3,8STN,6P0Z,5WHE,5WHD,7F0W,7EYX,9C3R,7XKJ,9RKC,9P45,9P44,9GBJ,9C40,8AZY,6ZL5,6GJ5,4EPR,6M9W,8AFC,9BG5,9U99,9U90,9U8Z,9U8U,8FMK,8FMJ,11QE,8EPW,8EBZ,7KFZ,6XGV,6OB3,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9E9I,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3N,9C3M,9U95,9U8W,9U97,9U8Y,9U8V	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10		small monomeric GTPase	L7RSL8_HUMAN	L7RSL8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1572211	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785349	US12466840, Example Ex-6	GTPase KRas	Homo sapiens		 1.60							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006227&target=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785349&enzyme=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7VVB,8T75,8T74,8T72,8T71,6FA1,6GOM,6FA3,6ASA,6FA2,6GQX,6GQT,6GQY,6GQW,6GJ8,4TQA,7W5R,7C41,7C40,6BOF,6MBQ,9KFL,7ROV,6O36,5VQ0,5VPZ,5VPY,5VPI,5VP7,6E6G,6E6F,5UFQ,4TQ9,6O46,9C41,6WS4,9C3Q,8G4F,6H47,6H46,5V9O,5V9L,5V71,5O2T,5O2S,5MLB,5MLA,5KYK,8STN,5WPM,5WLB,7F0W,7EYX,9C43,8UN4,7XKJ,8FMK,8FMJ,9C40,9RKC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572212	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785349	US12466840, Example Ex-6	GTPase KRas [G12C]	Homo sapiens		 6.50							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=864&target=GTPase+KRas+%5BG12C%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785349&enzyme=GTPase+KRas+%5BG12C%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JGD,7W5R,7C41,7C40,9KFL,4TQ9,5WPM,5WLB,7NY8,6YXW,6MQN,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,5VQ0,5VPZ,5VPY,5VPI,5VP7,6YR8,6GJ8,5UK9,5UFE,5WHB,5WHA,6GOE,5UFQ,6WS4,9C41,9C3Q,6P0Z,7ROV,9C43,7F0W,7EYX,6M9W,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,8STN,7XKJ,8FMK,8FMJ,9BG5,9C40,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3R,9U99,9U90	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572213	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785349	US12466840, Example Ex-6	GTPase KRas [G13D]	Homo sapiens		 1.90							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1403&target=GTPase+KRas+%5BG13D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785349&enzyme=GTPase+KRas+%5BG13D%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGDVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8CPR,8BLR,8UN3,8UN5,7NY8,6YXW,6MQN,6YR8,5UK9,5UFE,8TBJ,9BHQ,8TBN,9E3S,7TLK,9BHO,6P0Z,6M9W,9USB,9U5T,9CTB,9CTA,9CT9,9CT8,9CT7,9L6F,9L6A,9E5F,9E5D,9BI1,9BGH,8WB1,8TXH,8TXG,8TXE,8R7X,8R7W,7EWB,7EWA,7EW9,7ACQ,7ACH,7ACF,7ACA,6ZLI,6QUX,6QUW,6QUV,6GJ7,6GJ6,9BGC,8TBH,5XCO,9RKN,9RKJ,9RKE,6CU6,4QL3,6QUU,9BGA,9BFV,8TBK,8G9P,8TY9,8TY8,8TY2,8TXK,8TXJ,8TVK,7MDP,5USJ,5US4,9PIZ,9N9N,9BI2,9BHP,7A47,7A1Y,7A1X,7A1W,4NMM,4LDJ,4L8G,9KPN,9KPM,8G47,8G42,9PZY	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572214	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785349	US12466840, Example Ex-6	GTPase HRas	Homo sapiens		 5516							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1541&target=GTPase+HRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785349&enzyme=GTPase+HRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS	4Q21,6Q21,1Q21,1IOZ,1AA9,7VV9,6AMB,6KYH,7L0F,6AXG,5E95,8BEA,8BE9,8BE8,8BE7,8BE6,8WWC,8OSO,8OSN,8OSM,8CNN,8CNJ,8BWG,8BOS,7OGC,7OGB,7OGA,7OG9,5P21,4RSG,4NYM,4NYJ,4G0N,4DLW,4DLU,4DLT,4DLS,3TGP,3RSO,3RSL,3RS7,3RS5,3RS4,3RS3,3RS2,3RS0,3RRZ,3RRY,3LBN,3LBI,3LBH,3L8Z,3L8Y,3KUD,3K8Y,2RGE,1XD2,1WQ1,1QRA,1P2V,1P2U,1P2T,1P2S,1NVW,1NVV,1K8R,1GNR,1GNQ,1GNP,1CTQ,1CRR,1CRQ,1CRP,1BKD,121P,8TBG,6ZL3,6V9O,6V9N,6V9M,6V9L,6V9J,6V9F,6V94,6D5W,6D5V,6D5M,6D5L,6D5J,6D5H,6D5G,6D5E,6D59,6D56,6D55,6CUR,6CUP,6CUO,6BVM,6BVL,6BVK,6BVJ,6BVI,5WFR,5WFQ,5WFP,5WFO,4NYI,5WDO,5B30,5B2Z,4EFL,4US2,4US1,4US0,4URZ,4URY,4URX,4URW,4URV,4URU	GTPase HRas	RASH_HUMAN	P01112	B5BUA0 Q14080 Q6FHV9 Q9BR65 Q9UCE2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572215	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785349	US12466840, Example Ex-6	GTPase NRas	Homo sapiens		 10050							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006303&target=GTPase+NRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785349&enzyme=GTPase+NRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQGCMGLPCVVM	8TBI,3CON,8VM2,6ZIR,6ZIO,9BG0,5UHV,6WGH,4Q21,6MQT,6E6P,6E6C,6DZH,1AGP,421P,6ZJ0,821P,1PLL,1PLJ,1JAI,1CLU,7L0G,8TLR,4L9W,4L9S,1PLK,1JAH	GTPase NRas	RASN_HUMAN	P01111	Q14971 Q15104 Q15282																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572216	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785349	US12466840, Example Ex-6	GTPase KRas [G12A]	Homo sapiens		 1.000							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2069&target=GTPase+KRas+%5BG12A%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785349&enzyme=GTPase+KRas+%5BG12A%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAAGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6MQN,7W5R,7C41,7C40,7NY8,6YXW,9KFL,4TQ9,6YR8,5WPM,5WLB,5UK9,5UFE,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,5V9O,5V9L,5V71,5KYK,6GJ8,5WHB,5WHA,6GOE,9C41,6M9W,7ROV,6WS4,5UFQ,6P0Z,9C43,9BG5,9C3Q,8STN,8EPW,8EBZ,7KFZ,6XGV,6OB3,7F0W,7EYX,7RP3,9C40,7XKJ,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,9C3R,9U99,9U90,8FMK,8FMJ,11QE,9U8Z,9U8U,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,8AFC,9C3K,9C3V,9E9I,9U8X,9U8T,9C3Z,9U8V,9C3N,9C3M,9U95,9U8W,9U97,9U8Y	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572217	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785349	US12466840, Example Ex-6	GTPase KRas [G12S]	Homo sapiens		 1.20							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1374&target=GTPase+KRas+%5BG12S%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785349&enzyme=GTPase+KRas+%5BG12S%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGASGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6MQN,7NY8,6YXW,7W5R,7C41,7C40,6GJ8,9KFL,4TQ9,6YR8,5UK9,5UFE,9C41,5VQ0,5VPZ,5VPY,5VPI,5VP7,5UFQ,5V9O,5V9L,5V71,5KYK,6WS4,7ROV,5WPM,5WLB,9C3Q,9C43,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8STN,7F0W,7EYX,6P0Z,5WHB,5WHA,6M9W,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,6GOE,9C3R,9C40,7XKJ,9BG5,8FMK,8FMJ,11QE,9U99,9U90,7RP3,9U8Z,9U8U,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3M,9C3N,9U8V,8AFC,9U95,9U8W,9E9I,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9U97,9U8Y	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572218	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785349	US12466840, Example Ex-6	GTPase KRas [G12R]	Homo sapiens		 1.20							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2068&target=GTPase+KRas+%5BG12R%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785349&enzyme=GTPase+KRas+%5BG12R%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGARGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7W5R,7C41,7C40,6MQN,7NY8,6YXW,9KFL,6GJ8,4TQ9,9C41,6WS4,5UFQ,5UK9,5UFE,6YR8,9C3Q,7ROV,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,9C43,5WPM,5WLB,8STN,7F0W,7EYX,5WHB,5WHA,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GOE,5V9O,5V9L,5V71,5KYK,6M9W,9C40,7XKJ,6P0Z,9BG5,9C3R,9U8Z,9U8U,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,9U99,9U90,11QE,8FMK,8FMJ,9C3K,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3V,9U8X,9U8T,7RP3,9C3Z,9U95,9U8W,9U8V,9C3N,9C3M,9U97,9U8Y,8AFC,9E9I,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572219	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785349	US12466840, Example Ex-6	GTPase KRas [Q61H]	Homo sapiens		 1.80							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1404&target=GTPase+KRas+%5BQ61H%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785349&enzyme=GTPase+KRas+%5BQ61H%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGHEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6GQW,6MQN,7NY8,6YXW,8TBJ,5UK9,5UFE,6YR8,8TBN,9E3S,6P0Z,7TLK,9BHQ,9BHO,6M9W,9CTB,9CTA,9CT9,9CT8,9CT7,9BG5,9USB,9U5T,5XCO,9L6F,9L6A,9E5F,9E5D,9BI1,9BGH,8WB1,8TXH,8TXG,8TXE,8R7X,8R7W,8EPW,8EBZ,7KFZ,7EWB,7EWA,7EW9,7ACQ,7ACH,7ACF,7ACA,6ZLI,6XGV,6QUX,6QUW,6QUV,6OB3,6GJ7,6GJ6,9BGC,8TBH,6QUU,9BGA,9BFV,8TBK,8G9P,9RKN,9RKJ,9RKE,6CU6,4QL3,9PIZ,8TY9,8TY8,8TY2,8TXK,8TXJ,8TVK,7MDP,5USJ,5US4,9BI2,9BHP,7A47,7A1Y,7A1X,7A1W,4NMM,4LDJ,4L8G,9N9N,9KPN,9KPM,8G47,8G42,9PZY	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572220	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785350	US12466840, Example Ex-7	GTPase KRas [G12D]	Homo sapiens		 1.40							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1006&target=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785350&enzyme=GTPase+KRas+%5BG12D%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JHL,7NY8,6YXW,6MQN,7W5R,7C41,7C40,6YR8,5UK9,5UFE,7RSE,7RSC,6W4E,9KFL,4TQ9,5OCG,4DSU,4DST,4DSO,4DSN,6W4F,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8QVU,5WPM,5WLB,6P0Z,5VQ0,5VPZ,5VPY,5VPI,5VP7,5V9O,5V9L,5V71,5KYK,6M9W,5WHB,5WHA,9BG5,6GOE,8EPW,8EBZ,7KFZ,6XGV,6OB3,7RP3,8AFC,9UOH,8X6R,8V3A,8V39	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572221	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785350	US12466840, Example Ex-7	GTPase KRas [G12V]	Homo sapiens		 2.80							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1398&target=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785350&enzyme=GTPase+KRas+%5BG12V%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8PI0,7NY8,6YXW,6MQN,5V9O,5V9L,5V71,5KYK,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GJ8,9C41,5UK9,5UFE,6YR8,6WS4,9C43,5UFQ,7ROV,9C3Q,7RP3,8STN,6P0Z,5WHE,5WHD,7F0W,7EYX,9C3R,7XKJ,9RKC,9P45,9P44,9GBJ,9C40,8AZY,6ZL5,6GJ5,4EPR,6M9W,8AFC,9BG5,9U99,9U90,9U8Z,9U8U,8FMK,8FMJ,11QE,8EPW,8EBZ,7KFZ,6XGV,6OB3,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9E9I,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3N,9C3M,9U95,9U8W,9U97,9U8Y,9U8V	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10		small monomeric GTPase	L7RSL8_HUMAN	L7RSL8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1572222	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785350	US12466840, Example Ex-7	GTPase KRas	Homo sapiens		 1.40							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006227&target=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785350&enzyme=GTPase+KRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7VVB,8T75,8T74,8T72,8T71,6FA1,6GOM,6FA3,6ASA,6FA2,6GQX,6GQT,6GQY,6GQW,6GJ8,4TQA,7W5R,7C41,7C40,6BOF,6MBQ,9KFL,7ROV,6O36,5VQ0,5VPZ,5VPY,5VPI,5VP7,6E6G,6E6F,5UFQ,4TQ9,6O46,9C41,6WS4,9C3Q,8G4F,6H47,6H46,5V9O,5V9L,5V71,5O2T,5O2S,5MLB,5MLA,5KYK,8STN,5WPM,5WLB,7F0W,7EYX,9C43,8UN4,7XKJ,8FMK,8FMJ,9C40,9RKC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572223	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785350	US12466840, Example Ex-7	GTPase KRas [G12C]	Homo sapiens		 11.0							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=864&target=GTPase+KRas+%5BG12C%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785350&enzyme=GTPase+KRas+%5BG12C%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8JGD,7W5R,7C41,7C40,9KFL,4TQ9,5WPM,5WLB,7NY8,6YXW,6MQN,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,5VQ0,5VPZ,5VPY,5VPI,5VP7,6YR8,6GJ8,5UK9,5UFE,5WHB,5WHA,6GOE,5UFQ,6WS4,9C41,9C3Q,6P0Z,7ROV,9C43,7F0W,7EYX,6M9W,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,8STN,7XKJ,8FMK,8FMJ,9BG5,9C40,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3R,9U99,9U90	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572224	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785350	US12466840, Example Ex-7	GTPase KRas [G13D]	Homo sapiens		 2.40							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1403&target=GTPase+KRas+%5BG13D%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785350&enzyme=GTPase+KRas+%5BG13D%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGDVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	8CPR,8BLR,8UN3,8UN5,7NY8,6YXW,6MQN,6YR8,5UK9,5UFE,8TBJ,9BHQ,8TBN,9E3S,7TLK,9BHO,6P0Z,6M9W,9USB,9U5T,9CTB,9CTA,9CT9,9CT8,9CT7,9L6F,9L6A,9E5F,9E5D,9BI1,9BGH,8WB1,8TXH,8TXG,8TXE,8R7X,8R7W,7EWB,7EWA,7EW9,7ACQ,7ACH,7ACF,7ACA,6ZLI,6QUX,6QUW,6QUV,6GJ7,6GJ6,9BGC,8TBH,5XCO,9RKN,9RKJ,9RKE,6CU6,4QL3,6QUU,9BGA,9BFV,8TBK,8G9P,8TY9,8TY8,8TY2,8TXK,8TXJ,8TVK,7MDP,5USJ,5US4,9PIZ,9N9N,9BI2,9BHP,7A47,7A1Y,7A1X,7A1W,4NMM,4LDJ,4L8G,9KPN,9KPM,8G47,8G42,9PZY	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572225	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785350	US12466840, Example Ex-7	GTPase HRas	Homo sapiens		 2180							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1541&target=GTPase+HRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785350&enzyme=GTPase+HRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS	4Q21,6Q21,1Q21,1IOZ,1AA9,7VV9,6AMB,6KYH,7L0F,6AXG,5E95,8BEA,8BE9,8BE8,8BE7,8BE6,8WWC,8OSO,8OSN,8OSM,8CNN,8CNJ,8BWG,8BOS,7OGC,7OGB,7OGA,7OG9,5P21,4RSG,4NYM,4NYJ,4G0N,4DLW,4DLU,4DLT,4DLS,3TGP,3RSO,3RSL,3RS7,3RS5,3RS4,3RS3,3RS2,3RS0,3RRZ,3RRY,3LBN,3LBI,3LBH,3L8Z,3L8Y,3KUD,3K8Y,2RGE,1XD2,1WQ1,1QRA,1P2V,1P2U,1P2T,1P2S,1NVW,1NVV,1K8R,1GNR,1GNQ,1GNP,1CTQ,1CRR,1CRQ,1CRP,1BKD,121P,8TBG,6ZL3,6V9O,6V9N,6V9M,6V9L,6V9J,6V9F,6V94,6D5W,6D5V,6D5M,6D5L,6D5J,6D5H,6D5G,6D5E,6D59,6D56,6D55,6CUR,6CUP,6CUO,6BVM,6BVL,6BVK,6BVJ,6BVI,5WFR,5WFQ,5WFP,5WFO,4NYI,5WDO,5B30,5B2Z,4EFL,4US2,4US1,4US0,4URZ,4URY,4URX,4URW,4URV,4URU	GTPase HRas	RASH_HUMAN	P01112	B5BUA0 Q14080 Q6FHV9 Q9BR65 Q9UCE2																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572226	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785350	US12466840, Example Ex-7	GTPase NRas	Homo sapiens		 8979							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006303&target=GTPase+NRas&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785350&enzyme=GTPase+NRas&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQGCMGLPCVVM	8TBI,3CON,8VM2,6ZIR,6ZIO,9BG0,5UHV,6WGH,4Q21,6MQT,6E6P,6E6C,6DZH,1AGP,421P,6ZJ0,821P,1PLL,1PLJ,1JAI,1CLU,7L0G,8TLR,4L9W,4L9S,1PLK,1JAH	GTPase NRas	RASN_HUMAN	P01111	Q14971 Q15104 Q15282																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572227	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785350	US12466840, Example Ex-7	GTPase KRas [G12A]	Homo sapiens		 1.30							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2069&target=GTPase+KRas+%5BG12A%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785350&enzyme=GTPase+KRas+%5BG12A%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAAGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6MQN,7W5R,7C41,7C40,7NY8,6YXW,9KFL,4TQ9,6YR8,5WPM,5WLB,5UK9,5UFE,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,5V9O,5V9L,5V71,5KYK,6GJ8,5WHB,5WHA,6GOE,9C41,6M9W,7ROV,6WS4,5UFQ,6P0Z,9C43,9BG5,9C3Q,8STN,8EPW,8EBZ,7KFZ,6XGV,6OB3,7F0W,7EYX,7RP3,9C40,7XKJ,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,9C3R,9U99,9U90,8FMK,8FMJ,11QE,9U8Z,9U8U,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,8AFC,9C3K,9C3V,9E9I,9U8X,9U8T,9C3Z,9U8V,9C3N,9C3M,9U95,9U8W,9U97,9U8Y	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572228	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785350	US12466840, Example Ex-7	GTPase KRas [G12S]	Homo sapiens		 1.30							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1374&target=GTPase+KRas+%5BG12S%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785350&enzyme=GTPase+KRas+%5BG12S%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGASGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6MQN,7NY8,6YXW,7W5R,7C41,7C40,6GJ8,9KFL,4TQ9,6YR8,5UK9,5UFE,9C41,5VQ0,5VPZ,5VPY,5VPI,5VP7,5UFQ,5V9O,5V9L,5V71,5KYK,6WS4,7ROV,5WPM,5WLB,9C3Q,9C43,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,8STN,7F0W,7EYX,6P0Z,5WHB,5WHA,6M9W,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,6GOE,9C3R,9C40,7XKJ,9BG5,8FMK,8FMJ,11QE,9U99,9U90,7RP3,9U8Z,9U8U,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3K,9C3V,9U8X,9U8T,9C3Z,9C3M,9C3N,9U8V,8AFC,9U95,9U8W,9E9I,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC,9U97,9U8Y	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572229	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785350	US12466840, Example Ex-7	GTPase KRas [G12R]	Homo sapiens		 1.30							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2068&target=GTPase+KRas+%5BG12R%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785350&enzyme=GTPase+KRas+%5BG12R%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGARGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	7W5R,7C41,7C40,6MQN,7NY8,6YXW,9KFL,6GJ8,4TQ9,9C41,6WS4,5UFQ,5UK9,5UFE,6YR8,9C3Q,7ROV,8G4F,6H47,6H46,5O2T,5O2S,5MLB,5MLA,9C43,5WPM,5WLB,8STN,7F0W,7EYX,5WHB,5WHA,5VQ0,5VPZ,5VPY,5VPI,5VP7,6GOE,5V9O,5V9L,5V71,5KYK,6M9W,9C40,7XKJ,6P0Z,9BG5,9C3R,9U8Z,9U8U,9RKC,9P45,9P44,9GBJ,8AZY,6ZL5,6GJ5,4EPR,9U99,9U90,11QE,8FMK,8FMJ,9C3K,8EPW,8EBZ,7KFZ,6XGV,6OB3,9C3V,9U8X,9U8T,7RP3,9C3Z,9U95,9U8W,9U8V,9C3N,9C3M,9U97,9U8Y,8AFC,9E9I,9UOH,8X6R,8V3A,8V39,8QUG,8AZX,8AFB,7YCE,7YCC	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1572230	CCc1c(F)ccc2cc3[nH]nc(C)c3c(-c3nc4c5c(nc(OC[C@@]67CCCN6C/C(=C\F)C7)nc5c3F)N3CCCOC[C@H]3CO4)c12			785350	US12466840, Example Ex-7	GTPase KRas [Q61H]	Homo sapiens		 2.80							Curated from the literature by BindingDB						n/a	11/11/2025	3/2/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=785350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1404&target=GTPase+KRas+%5BQ61H%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=785350&enzyme=GTPase+KRas+%5BQ61H%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGHEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM	6GQW,6MQN,7NY8,6YXW,8TBJ,5UK9,5UFE,6YR8,8TBN,9E3S,6P0Z,7TLK,9BHQ,9BHO,6M9W,9CTB,9CTA,9CT9,9CT8,9CT7,9BG5,9USB,9U5T,5XCO,9L6F,9L6A,9E5F,9E5D,9BI1,9BGH,8WB1,8TXH,8TXG,8TXE,8R7X,8R7W,8EPW,8EBZ,7KFZ,7EWB,7EWA,7EW9,7ACQ,7ACH,7ACF,7ACA,6ZLI,6XGV,6QUX,6QUW,6QUV,6OB3,6GJ7,6GJ6,9BGC,8TBH,6QUU,9BGA,9BFV,8TBK,8G9P,9RKN,9RKJ,9RKE,6CU6,4QL3,9PIZ,8TY9,8TY8,8TY2,8TXK,8TXJ,8TVK,7MDP,5USJ,5US4,9BI2,9BHP,7A47,7A1Y,7A1X,7A1W,4NMM,4LDJ,4L8G,9N9N,9KPN,9KPM,8G47,8G42,9PZY	GTPase KRas	RASK_HUMAN	P01116	A8K8Z5 B0LPF9 P01118 Q96D10