BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
1578554	CC(C)(C)OC(=O)NC12CC3CC(CC(N)(C3)C1)C2			789046	tert-butyl (3-aminoadamantan-1-yl)carbamate::US20250353833, Compound 4	Dipeptidyl peptidase 4	Homo sapiens		 10.00							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789046&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578555	CC(C)(C)OC(=O)NC12CC3CC(CC(N)(C3)C1)C2			789046	tert-butyl (3-aminoadamantan-1-yl)carbamate::US20250353833, Compound 4	Dipeptidyl peptidase 8	Homo sapiens		 2200							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789046&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578556	CC(C)(C)OC(=O)NC12CC3CC(CC(N)(C3)C1)C2			789046	tert-butyl (3-aminoadamantan-1-yl)carbamate::US20250353833, Compound 4	Dipeptidyl peptidase 9	Homo sapiens		 230							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789046&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578557	CC(C)(C)OC(=O)NC12CC3CC(CC(N)(C3)C1)C2			789046	tert-butyl (3-aminoadamantan-1-yl)carbamate::US20250353833, Compound 4	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789046&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578558	CC(C)(C)OC(=O)NC12CC3CC(CC(N)(C3)C1)C2			789046	tert-butyl (3-aminoadamantan-1-yl)carbamate::US20250353833, Compound 4	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789046&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578559	CC(C)(C)OC(=O)NC12CC3CC(CC(N)(C3)C1)C2			789046	tert-butyl (3-aminoadamantan-1-yl)carbamate::US20250353833, Compound 4	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789046&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578560	N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789047	(S)-1-((-3-(benzyloxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5a	Dipeptidyl peptidase 4	Homo sapiens		 4.80							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789047&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578561	N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789047	(S)-1-((-3-(benzyloxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5a	Dipeptidyl peptidase 8	Homo sapiens		 1320							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789047&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578562	N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789047	(S)-1-((-3-(benzyloxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5a	Dipeptidyl peptidase 9	Homo sapiens		 130							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789047&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578563	N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789047	(S)-1-((-3-(benzyloxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5a	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789047&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578564	N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789047	(S)-1-((-3-(benzyloxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5a	Prolyl endopeptidase FAP	Homo sapiens		 4000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789047&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578565	N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789047	(S)-1-((-3-(benzyloxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5a	Presequence protease, mitochondrial	Homo sapiens		 4300							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789047&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578566	N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789048	(S)-1-((-3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5b	Dipeptidyl peptidase 4	Homo sapiens		 5.00							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789048&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578567	N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789048	(S)-1-((-3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5b	Dipeptidyl peptidase 8	Homo sapiens		 540							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789048&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578568	N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789048	(S)-1-((-3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5b	Dipeptidyl peptidase 9	Homo sapiens		 52.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789048&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578569	N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789048	(S)-1-((-3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5b	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789048&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578570	N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789048	(S)-1-((-3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5b	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789048&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578571	N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789048	(S)-1-((-3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5b	Presequence protease, mitochondrial	Homo sapiens		 2200							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789048&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578572	CCCCOC12CC3CC(CC(NCC(=O)N4CCC[C@H]4C#N)(C3)C1)C2			789049	(2S)-1-((-3-butoxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5c	Dipeptidyl peptidase 4	Homo sapiens		 12.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789049	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789049&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578573	CCCCOC12CC3CC(CC(NCC(=O)N4CCC[C@H]4C#N)(C3)C1)C2			789049	(2S)-1-((-3-butoxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5c	Dipeptidyl peptidase 8	Homo sapiens		 1250							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789049	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789049&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578574	CCCCOC12CC3CC(CC(NCC(=O)N4CCC[C@H]4C#N)(C3)C1)C2			789049	(2S)-1-((-3-butoxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5c	Dipeptidyl peptidase 9	Homo sapiens		 150							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789049	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789049&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578575	CCCCOC12CC3CC(CC(NCC(=O)N4CCC[C@H]4C#N)(C3)C1)C2			789049	(2S)-1-((-3-butoxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5c	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789049	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789049&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578576	CCCCOC12CC3CC(CC(NCC(=O)N4CCC[C@H]4C#N)(C3)C1)C2			789049	(2S)-1-((-3-butoxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5c	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789049	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789049&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578577	CCCCOC12CC3CC(CC(NCC(=O)N4CCC[C@H]4C#N)(C3)C1)C2			789049	(2S)-1-((-3-butoxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5c	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789049	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789049&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578578	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2			789051	(2S,4S)-4-azido-1-((-3-hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5d	Dipeptidyl peptidase 4	Homo sapiens		 32.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789051	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789051&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578579	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2			789051	(2S,4S)-4-azido-1-((-3-hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5d	Dipeptidyl peptidase 8	Homo sapiens		 150							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789051	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789051&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578580	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2			789051	(2S,4S)-4-azido-1-((-3-hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5d	Dipeptidyl peptidase 9	Homo sapiens		 16.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789051	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789051&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578581	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2			789051	(2S,4S)-4-azido-1-((-3-hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5d	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789051	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789051&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578582	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2			789051	(2S,4S)-4-azido-1-((-3-hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5d	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789051	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789051&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578583	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2			789051	(2S,4S)-4-azido-1-((-3-hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5d	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789051	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789051&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578584	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789052	(2S,4S)-4-azido-1-((3-(benzyloxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5e	Dipeptidyl peptidase 4	Homo sapiens		 17.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789052&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578585	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789052	(2S,4S)-4-azido-1-((3-(benzyloxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5e	Dipeptidyl peptidase 8	Homo sapiens		 60.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789052&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578586	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789052	(2S,4S)-4-azido-1-((3-(benzyloxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5e	Dipeptidyl peptidase 9	Homo sapiens		 10.00							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789052&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578587	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789052	(2S,4S)-4-azido-1-((3-(benzyloxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5e	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789052&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578588	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789052	(2S,4S)-4-azido-1-((3-(benzyloxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5e	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789052&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578589	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789052	(2S,4S)-4-azido-1-((3-(benzyloxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5e	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789052&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578590	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789053	(2S,4S)-4-azido-1-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5f	Dipeptidyl peptidase 4	Homo sapiens		 24.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789053	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789053&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578591	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789053	(2S,4S)-4-azido-1-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5f	Dipeptidyl peptidase 8	Homo sapiens		 41.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789053	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789053&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578592	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789053	(2S,4S)-4-azido-1-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5f	Dipeptidyl peptidase 9	Homo sapiens		 6.00							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789053	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789053&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578593	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789053	(2S,4S)-4-azido-1-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5f	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789053	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789053&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578594	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789053	(2S,4S)-4-azido-1-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5f	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789053	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789053&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578595	N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789053	(2S,4S)-4-azido-1-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5f	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789053	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789053&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578596	CCCCOC12CC3CC(CC(NCC(=O)N4C[C@@H](N=[N+]=[N-])C[C@H]4C#N)(C3)C1)C2			789054	(2S,4S)-4-azido-1-((3-butoxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5g	Dipeptidyl peptidase 4	Homo sapiens		 13000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789054	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789054&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578597	CCCCOC12CC3CC(CC(NCC(=O)N4C[C@@H](N=[N+]=[N-])C[C@H]4C#N)(C3)C1)C2			789054	(2S,4S)-4-azido-1-((3-butoxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5g	Dipeptidyl peptidase 8	Homo sapiens		 270							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789054	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789054&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578598	CCCCOC12CC3CC(CC(NCC(=O)N4C[C@@H](N=[N+]=[N-])C[C@H]4C#N)(C3)C1)C2			789054	(2S,4S)-4-azido-1-((3-butoxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5g	Dipeptidyl peptidase 9	Homo sapiens		 35.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789054	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789054&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578599	CCCCOC12CC3CC(CC(NCC(=O)N4C[C@@H](N=[N+]=[N-])C[C@H]4C#N)(C3)C1)C2			789054	(2S,4S)-4-azido-1-((3-butoxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5g	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789054	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789054&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578600	CCCCOC12CC3CC(CC(NCC(=O)N4C[C@@H](N=[N+]=[N-])C[C@H]4C#N)(C3)C1)C2			789054	(2S,4S)-4-azido-1-((3-butoxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5g	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789054	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789054&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578601	CCCCOC12CC3CC(CC(NCC(=O)N4C[C@@H](N=[N+]=[N-])C[C@H]4C#N)(C3)C1)C2			789054	(2S,4S)-4-azido-1-((3-butoxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile::US20250353833, Compound 5g	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789054	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789054&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578602	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(CC(O)(C4)C2)C3)C1			789055	US20250353833, Compound 5h	Dipeptidyl peptidase 4	Homo sapiens		 230							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789055&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578603	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(CC(O)(C4)C2)C3)C1			789055	US20250353833, Compound 5h	Dipeptidyl peptidase 8	Homo sapiens		 1000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789055&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578604	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(CC(O)(C4)C2)C3)C1			789055	US20250353833, Compound 5h	Dipeptidyl peptidase 9	Homo sapiens		 260							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789055&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578605	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(CC(O)(C4)C2)C3)C1			789055	US20250353833, Compound 5h	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789055&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578606	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(CC(O)(C4)C2)C3)C1			789055	US20250353833, Compound 5h	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789055&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578607	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(CC(O)(C4)C2)C3)C1			789055	US20250353833, Compound 5h	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789055&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578608	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCc2ccccc2)(C4)C3)C1			789056	(S)-1-((3-(benzyloxy)adamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5i	Dipeptidyl peptidase 4	Homo sapiens		 280							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789056&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578609	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCc2ccccc2)(C4)C3)C1			789056	(S)-1-((3-(benzyloxy)adamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5i	Dipeptidyl peptidase 8	Homo sapiens		 340							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789056&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578610	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCc2ccccc2)(C4)C3)C1			789056	(S)-1-((3-(benzyloxy)adamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5i	Dipeptidyl peptidase 9	Homo sapiens		 120							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789056&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578611	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCc2ccccc2)(C4)C3)C1			789056	(S)-1-((3-(benzyloxy)adamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5i	Dipeptidyl peptidase 2	Homo sapiens		 1270							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789056&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578612	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCc2ccccc2)(C4)C3)C1			789056	(S)-1-((3-(benzyloxy)adamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5i	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789056&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578613	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCc2ccccc2)(C4)C3)C1			789056	(S)-1-((3-(benzyloxy)adamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5i	Presequence protease, mitochondrial	Homo sapiens		 8920							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789056&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578614	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCc2ccc(F)cc2F)(C4)C3)C1			789057	(2S)-1-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5j	Dipeptidyl peptidase 4	Homo sapiens		 410							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789057	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789057&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578615	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCc2ccc(F)cc2F)(C4)C3)C1			789057	(2S)-1-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5j	Dipeptidyl peptidase 8	Homo sapiens		 370							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789057	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789057&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578616	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCc2ccc(F)cc2F)(C4)C3)C1			789057	(2S)-1-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5j	Dipeptidyl peptidase 9	Homo sapiens		 130							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789057	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789057&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578617	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCc2ccc(F)cc2F)(C4)C3)C1			789057	(2S)-1-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5j	Dipeptidyl peptidase 2	Homo sapiens		 1100							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789057	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789057&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578618	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCc2ccc(F)cc2F)(C4)C3)C1			789057	(2S)-1-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5j	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789057	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789057&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578619	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCc2ccc(F)cc2F)(C4)C3)C1			789057	(2S)-1-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5j	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789057	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789057&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578620	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCCCC)(C4)C3)C1			789058	(S)-1-((-3-butoxyadamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5k	Dipeptidyl peptidase 4	Homo sapiens		 320							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789058	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789058&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578621	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCCCC)(C4)C3)C1			789058	(S)-1-((-3-butoxyadamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5k	Dipeptidyl peptidase 8	Homo sapiens		 530							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789058	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789058&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578622	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCCCC)(C4)C3)C1			789058	(S)-1-((-3-butoxyadamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5k	Dipeptidyl peptidase 9	Homo sapiens		 210							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789058	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789058&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578623	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCCCC)(C4)C3)C1			789058	(S)-1-((-3-butoxyadamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5k	Dipeptidyl peptidase 2	Homo sapiens		 1200							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789058	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789058&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578624	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCCCC)(C4)C3)C1			789058	(S)-1-((-3-butoxyadamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5k	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789058	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789058&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578625	C=C1C[C@@H](C#N)N(C(=O)CNC23CC4CC(C2)CC(OCCCC)(C4)C3)C1			789058	(S)-1-((-3-butoxyadamantan-1-yl)glycyl)-4-methylenepyrrolidine-2-carbonitrile::US20250353833, Compound 5k	Presequence protease, mitochondrial	Homo sapiens		 2200							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789058	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789058&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578626	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2			789059	US20250353833, Compound 5l	Dipeptidyl peptidase 4	Homo sapiens		 180							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789059	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789059&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578627	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2			789059	US20250353833, Compound 5l	Dipeptidyl peptidase 8	Homo sapiens		 21400							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789059	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789059&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578628	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2			789059	US20250353833, Compound 5l	Dipeptidyl peptidase 9	Homo sapiens		 1220							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789059	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789059&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578629	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2			789059	US20250353833, Compound 5l	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789059	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789059&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578630	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2			789059	US20250353833, Compound 5l	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789059	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789059&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578631	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2			789059	US20250353833, Compound 5l	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789059	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789059&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578632	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789060	(1R,2S,5S)-3-((-3-(benzyloxy)adamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5m	Dipeptidyl peptidase 4	Homo sapiens		 100.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789060	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789060&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578633	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789060	(1R,2S,5S)-3-((-3-(benzyloxy)adamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5m	Dipeptidyl peptidase 8	Homo sapiens		 5900							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789060	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789060&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578634	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789060	(1R,2S,5S)-3-((-3-(benzyloxy)adamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5m	Dipeptidyl peptidase 9	Homo sapiens		 670							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789060	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789060&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578635	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789060	(1R,2S,5S)-3-((-3-(benzyloxy)adamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5m	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789060	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789060&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578636	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789060	(1R,2S,5S)-3-((-3-(benzyloxy)adamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5m	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789060	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789060&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578637	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2			789060	(1R,2S,5S)-3-((-3-(benzyloxy)adamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5m	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789060	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789060&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578638	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789061	(1R,2S,5S)-3-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5n	Dipeptidyl peptidase 4	Homo sapiens		 200							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789061	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789061&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578639	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789061	(1R,2S,5S)-3-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5n	Dipeptidyl peptidase 8	Homo sapiens		 2000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789061	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789061&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578640	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789061	(1R,2S,5S)-3-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5n	Dipeptidyl peptidase 9	Homo sapiens		 620							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789061	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789061&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578641	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789061	(1R,2S,5S)-3-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5n	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789061	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789061&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578642	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789061	(1R,2S,5S)-3-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5n	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789061	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789061&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578643	N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2			789061	(1R,2S,5S)-3-((3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5n	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789061	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789061&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578644	CCCCOC12CC3CC(CC(NCC(=O)N4C[C@H]5C[C@H]5[C@H]4C#N)(C3)C1)C2			789062	(1R,2S,5S)-3-((-3-butoxyadamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5o	Dipeptidyl peptidase 4	Homo sapiens		 150							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789062	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789062&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578645	CCCCOC12CC3CC(CC(NCC(=O)N4C[C@H]5C[C@H]5[C@H]4C#N)(C3)C1)C2			789062	(1R,2S,5S)-3-((-3-butoxyadamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5o	Dipeptidyl peptidase 8	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789062	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789062&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578646	CCCCOC12CC3CC(CC(NCC(=O)N4C[C@H]5C[C@H]5[C@H]4C#N)(C3)C1)C2			789062	(1R,2S,5S)-3-((-3-butoxyadamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5o	Dipeptidyl peptidase 9	Homo sapiens		 990							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789062	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789062&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578647	CCCCOC12CC3CC(CC(NCC(=O)N4C[C@H]5C[C@H]5[C@H]4C#N)(C3)C1)C2			789062	(1R,2S,5S)-3-((-3-butoxyadamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5o	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789062	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789062&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578648	CCCCOC12CC3CC(CC(NCC(=O)N4C[C@H]5C[C@H]5[C@H]4C#N)(C3)C1)C2			789062	(1R,2S,5S)-3-((-3-butoxyadamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5o	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789062	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789062&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578649	CCCCOC12CC3CC(CC(NCC(=O)N4C[C@H]5C[C@H]5[C@H]4C#N)(C3)C1)C2			789062	(1R,2S,5S)-3-((-3-butoxyadamantan-1-yl)glycyl)-3-azabicyclo[3.1.0]hexane-2-carbonitrile::US20250353833, Compound 5o	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789062	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789062&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578650	O=C(CNC12CC3CC(CC(O)(C3)C1)C2)N1Cc2ccccc2C1			789063	2-((-3-hydroxyadamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5p	Dipeptidyl peptidase 4	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789063	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789063&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578651	O=C(CNC12CC3CC(CC(O)(C3)C1)C2)N1Cc2ccccc2C1			789063	2-((-3-hydroxyadamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5p	Dipeptidyl peptidase 8	Homo sapiens		 17700							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789063	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789063&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578652	O=C(CNC12CC3CC(CC(O)(C3)C1)C2)N1Cc2ccccc2C1			789063	2-((-3-hydroxyadamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5p	Dipeptidyl peptidase 9	Homo sapiens		 4100							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789063	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789063&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578653	O=C(CNC12CC3CC(CC(O)(C3)C1)C2)N1Cc2ccccc2C1			789063	2-((-3-hydroxyadamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5p	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789063	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789063&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578654	O=C(CNC12CC3CC(CC(O)(C3)C1)C2)N1Cc2ccccc2C1			789063	2-((-3-hydroxyadamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5p	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789063	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789063&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578655	O=C(CNC12CC3CC(CC(O)(C3)C1)C2)N1Cc2ccccc2C1			789063	2-((-3-hydroxyadamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5p	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789063	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789063&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578656	O=C(CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2)N1Cc2ccccc2C1			789064	2-((3-(benzyloxy)adamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5q	Dipeptidyl peptidase 4	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789064	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789064&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578657	O=C(CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2)N1Cc2ccccc2C1			789064	2-((3-(benzyloxy)adamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5q	Dipeptidyl peptidase 8	Homo sapiens		 6900							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789064	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789064&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578658	O=C(CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2)N1Cc2ccccc2C1			789064	2-((3-(benzyloxy)adamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5q	Dipeptidyl peptidase 9	Homo sapiens		 1200							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789064	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789064&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578659	O=C(CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2)N1Cc2ccccc2C1			789064	2-((3-(benzyloxy)adamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5q	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789064	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789064&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578660	O=C(CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2)N1Cc2ccccc2C1			789064	2-((3-(benzyloxy)adamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5q	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789064	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789064&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578661	O=C(CNC12CC3CC(C1)CC(OCc1ccccc1)(C3)C2)N1Cc2ccccc2C1			789064	2-((3-(benzyloxy)adamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5q	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789064	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789064&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578662	O=C(CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2)N1Cc2ccccc2C1			789065	2-((-3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5r	Dipeptidyl peptidase 4	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789065	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789065&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578663	O=C(CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2)N1Cc2ccccc2C1			789065	2-((-3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5r	Dipeptidyl peptidase 8	Homo sapiens		 1540							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789065	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789065&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578664	O=C(CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2)N1Cc2ccccc2C1			789065	2-((-3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5r	Dipeptidyl peptidase 9	Homo sapiens		 380							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789065	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789065&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578665	O=C(CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2)N1Cc2ccccc2C1			789065	2-((-3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5r	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789065	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789065&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578666	O=C(CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2)N1Cc2ccccc2C1			789065	2-((-3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5r	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789065	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789065&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578667	O=C(CNC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2)N1Cc2ccccc2C1			789065	2-((-3-((2,4-difluorobenzyl)oxy)adamantan-1-yl)amino)-1-(isoindolin-2-yl)ethan-1-one::US20250353833, Compound 5r	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789065	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789065&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578668	CCCCOC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:4:5:8:12.11.10,THB:13:5:8:12.11.10,13:11:8:27.6.5,14:11:8:27.6.5,6:7:10:27.5.13,6:5:8.7.12:10|			50629039	CHEMBL5440616::US20250353833, Compound 5s	Dipeptidyl peptidase 4	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629039&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search			172471703	505047011							1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578669	CCCCOC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:4:5:8:12.11.10,THB:13:5:8:12.11.10,13:11:8:27.6.5,14:11:8:27.6.5,6:7:10:27.5.13,6:5:8.7.12:10|			50629039	CHEMBL5440616::US20250353833, Compound 5s	Dipeptidyl peptidase 8	Homo sapiens		 3100							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629039&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172471703	505047011							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578670	CCCCOC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:4:5:8:12.11.10,THB:13:5:8:12.11.10,13:11:8:27.6.5,14:11:8:27.6.5,6:7:10:27.5.13,6:5:8.7.12:10|			50629039	CHEMBL5440616::US20250353833, Compound 5s	Dipeptidyl peptidase 9	Homo sapiens		 490							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629039&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search			172471703	505047011							1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578671	CCCCOC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:4:5:8:12.11.10,THB:13:5:8:12.11.10,13:11:8:27.6.5,14:11:8:27.6.5,6:7:10:27.5.13,6:5:8.7.12:10|			50629039	CHEMBL5440616::US20250353833, Compound 5s	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629039&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search			172471703	505047011							1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578672	CCCCOC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:4:5:8:12.11.10,THB:13:5:8:12.11.10,13:11:8:27.6.5,14:11:8:27.6.5,6:7:10:27.5.13,6:5:8.7.12:10|			50629039	CHEMBL5440616::US20250353833, Compound 5s	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629039&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search			172471703	505047011							1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578673	CCCCOC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:4:5:8:12.11.10,THB:13:5:8:12.11.10,13:11:8:27.6.5,14:11:8:27.6.5,6:7:10:27.5.13,6:5:8.7.12:10|			50629039	CHEMBL5440616::US20250353833, Compound 5s	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629039&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search			172471703	505047011							1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578674	CC(C)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789067	1-(isoindolin-2-yl)-2-((-3-isopropoxyadamantan-1-yl)amino)ethan-1-one::US20250353833, Compound 5t	Dipeptidyl peptidase 4	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789067	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789067&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578675	CC(C)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789067	1-(isoindolin-2-yl)-2-((-3-isopropoxyadamantan-1-yl)amino)ethan-1-one::US20250353833, Compound 5t	Dipeptidyl peptidase 8	Homo sapiens		 4000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789067	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789067&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578676	CC(C)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789067	1-(isoindolin-2-yl)-2-((-3-isopropoxyadamantan-1-yl)amino)ethan-1-one::US20250353833, Compound 5t	Dipeptidyl peptidase 9	Homo sapiens		 610							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789067	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789067&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578677	CC(C)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789067	1-(isoindolin-2-yl)-2-((-3-isopropoxyadamantan-1-yl)amino)ethan-1-one::US20250353833, Compound 5t	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789067	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789067&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578678	CC(C)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789067	1-(isoindolin-2-yl)-2-((-3-isopropoxyadamantan-1-yl)amino)ethan-1-one::US20250353833, Compound 5t	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789067	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789067&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578679	CC(C)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789067	1-(isoindolin-2-yl)-2-((-3-isopropoxyadamantan-1-yl)amino)ethan-1-one::US20250353833, Compound 5t	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789067	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789067&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578680	CCCCCCCCOC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789068	1-(isoindolin-2-yl)-2-((-3-(octyloxy)adamantan-1-yl)amino)ethan-1-one::US20250353833, Compound 5u	Dipeptidyl peptidase 4	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789068	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1234&target=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789068&enzyme=Dipeptidyl+peptidase+4&column=ki&startPg=0&Increment=50&submit=Search											1	MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP	9D56,9CAR,2BGR,2JID,3F8S,2QJR,3W2T,3VJM,3VJL,3VJK,1WCY,1J2E,1PFQ,8ZDX,2RIP,9JMM,9JMJ,5Y7K,5Y7J,5Y7H,4LKO,4L72,4JH0,4J3J,4DTC,4DSZ,4DSA,3OC0,3KWJ,3KWF,3H0C,3EIO,3BJM,2OQI,2OLE,2OGZ,2BUB,2BGN,2AJL,1W1I,1TKR,1TK3,1RWQ,1NU8,1NU6,1N1M,8WKU,4QZV,3SX4,3SWW,3Q0T,3NOX,2RGU,1R9N,9GOH,5KBY,4KR0,4G1F,3OPM,3O9V,3O95,3G0G,3G0D,3G0C,3G0B,3CCC,3CCB,1U8E,1R9M,3WQH,9V2P,9V2L,6B1O,6B1E,5T4H,5T4F,5T4E,5T4B,5ISM,5I7U,4PNZ,4N8E,4N8D,4A5S,3HAC,3HAB,3D4L,3C45,3C43,2QOE,2QKY,2P8S,2OPH,2IIV,2IIT,2HHA,2FJP,1X70,2ONC,8Z4T,5ZID,5J3J,2OQV,2OAG,2I78,2I03,2G63,2G5T,2G5P,3Q8W,9LBT,5LLS	Dipeptidyl peptidase 4	DPP4_HUMAN	P27487	Q53TN1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578681	CCCCCCCCOC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789068	1-(isoindolin-2-yl)-2-((-3-(octyloxy)adamantan-1-yl)amino)ethan-1-one::US20250353833, Compound 5u	Dipeptidyl peptidase 8	Homo sapiens		 3300							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789068	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789068&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578682	CCCCCCCCOC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789068	1-(isoindolin-2-yl)-2-((-3-(octyloxy)adamantan-1-yl)amino)ethan-1-one::US20250353833, Compound 5u	Dipeptidyl peptidase 9	Homo sapiens		 500							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789068	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789068&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578683	CCCCCCCCOC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789068	1-(isoindolin-2-yl)-2-((-3-(octyloxy)adamantan-1-yl)amino)ethan-1-one::US20250353833, Compound 5u	Dipeptidyl peptidase 2	Homo sapiens		>5000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789068	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5468&target=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789068&enzyme=Dipeptidyl+peptidase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL	4EBB,3N0T,3JYH	Dipeptidyl peptidase 2	DPP2_HUMAN	Q9UHL4	A8K7U7 Q5VSF1 Q969X4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578684	CCCCCCCCOC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789068	1-(isoindolin-2-yl)-2-((-3-(octyloxy)adamantan-1-yl)amino)ethan-1-one::US20250353833, Compound 5u	Prolyl endopeptidase FAP	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789068	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5699&target=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789068&enzyme=Prolyl+endopeptidase+FAP&column=ki&startPg=0&Increment=50&submit=Search											1	MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD	9DVR,9DVQ,6Y0F,1Z68	Prolyl endopeptidase FAP	SEPR_HUMAN	Q12884	O00199 Q53TP5 Q86Z29 Q99998 Q9UID4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578685	CCCCCCCCOC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789068	1-(isoindolin-2-yl)-2-((-3-(octyloxy)adamantan-1-yl)amino)ethan-1-one::US20250353833, Compound 5u	Presequence protease, mitochondrial	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789068	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006502&target=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789068&enzyme=Presequence+protease%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search											1	MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIQ	4RPU,4NGE,4L3T	Presequence protease, mitochondrial	PREP_HUMAN	Q5JRX3	B3KMJ6 B4E0J8 C9JSL2 E7ES23 O95204 Q2M2G6 Q4VBR1 Q5JRW7 Q7L5Z7 Q9BSI6 Q9BVJ5 Q9UPP8																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578686	CCCCNC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1Cc2ccccc2C1 |TLB:4:5:8:11.12.13,10:5:8.9.11:13,THB:14:5:8:11.12.13,14:12:8:6.10.5,15:12:8:6.10.5,10:9:13:6.5.14|			50628991	CHEMBL5414516::US20250353833, Compound 25	Dipeptidyl peptidase 8	Homo sapiens		>10000							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628991&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172451192	505046963							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578687	CCCCNC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1Cc2ccccc2C1 |TLB:4:5:8:11.12.13,10:5:8.9.11:13,THB:14:5:8:11.12.13,14:12:8:6.10.5,15:12:8:6.10.5,10:9:13:6.5.14|			50628991	CHEMBL5414516::US20250353833, Compound 25	Dipeptidyl peptidase 8	Homo sapiens		 477							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628991&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172451192	505046963							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578688	N#Cc1ccc(CNC23CC4CC(CC(NCC(=O)N5Cc6ccccc6C5)(C4)C2)C3)cc1			789071	UAMC-000-3916::US20250353833, Compound 26	Dipeptidyl peptidase 8	Homo sapiens		 672							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789071	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789071&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578689	N#Cc1ccc(CNC23CC4CC(CC(NCC(=O)N5Cc6ccccc6C5)(C4)C2)C3)cc1			789071	UAMC-000-3916::US20250353833, Compound 26	Dipeptidyl peptidase 8	Homo sapiens		 50.6							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789071	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789071&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578690	O=C(CNC12CC3CC(C1)CC(NCc1ccc(-c4ccccc4)cc1)(C3)C2)N1Cc2ccccc2C1			789072	UAMC-000-3929::US20250353833, Compound 27	Dipeptidyl peptidase 8	Homo sapiens		 1540							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789072	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789072&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578691	O=C(CNC12CC3CC(C1)CC(NCc1ccc(-c4ccccc4)cc1)(C3)C2)N1Cc2ccccc2C1			789072	UAMC-000-3929::US20250353833, Compound 27	Dipeptidyl peptidase 8	Homo sapiens		 93.2							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789072	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789072&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578692	CC(C)(C)OC(=O)NC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:7:8:11:15.14.13,THB:16:8:11:15.14.13,16:14:11:30.9.8,17:14:11:30.9.8,9:10:13:30.8.16,9:8:11.10.15:13|			50629021	CHEMBL5399745::US20250353833, Compound 28	Dipeptidyl peptidase 8	Homo sapiens		 1140							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629021&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605922	505046993							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578693	CC(C)(C)OC(=O)NC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:7:8:11:15.14.13,THB:16:8:11:15.14.13,16:14:11:30.9.8,17:14:11:30.9.8,9:10:13:30.8.16,9:8:11.10.15:13|			50629021	CHEMBL5399745::US20250353833, Compound 28	Dipeptidyl peptidase 8	Homo sapiens		 4.73							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629021&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605922	505046993							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578694	OCCCCNC(=O)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:8:9:12:16.15.14,THB:17:9:12:16.15.14,17:15:12:31.10.9,18:15:12:31.10.9,10:11:14:31.9.17,10:9:12.11.16:14|			50629001	CHEMBL5431471::US20250353833, Compound 29	Dipeptidyl peptidase 8	Homo sapiens		 2600							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629001	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629001&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605970	505046973							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578695	OCCCCNC(=O)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:8:9:12:16.15.14,THB:17:9:12:16.15.14,17:15:12:31.10.9,18:15:12:31.10.9,10:11:14:31.9.17,10:9:12.11.16:14|			50629001	CHEMBL5431471::US20250353833, Compound 29	Dipeptidyl peptidase 8	Homo sapiens		 243							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629001	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629001&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605970	505046973							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578696	CC(C)(C)NC(=O)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:7:8:11:15.14.13,THB:16:8:11:15.14.13,16:14:11:30.9.8,17:14:11:30.9.8,9:10:13:30.8.16,9:8:11.10.15:13|			50628998	CHEMBL5426720::US20250353833, Compound 30	Dipeptidyl peptidase 8	Homo sapiens		 2590							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628998	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628998&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172463062	505046970							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578697	CC(C)(C)NC(=O)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:7:8:11:15.14.13,THB:16:8:11:15.14.13,16:14:11:30.9.8,17:14:11:30.9.8,9:10:13:30.8.16,9:8:11.10.15:13|			50628998	CHEMBL5426720::US20250353833, Compound 30	Dipeptidyl peptidase 8	Homo sapiens		 1.98							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628998	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628998&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172463062	505046970							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578698	CCC(C)(C)OC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789078	UAMC-000-4289::US20250353833, Compound 31	Dipeptidyl peptidase 8	Homo sapiens		 4710							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789078	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789078&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578699	CCC(C)(C)OC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2			789078	UAMC-000-4289::US20250353833, Compound 31	Dipeptidyl peptidase 8	Homo sapiens		 378							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789078	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789078&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578700	Fc1ccc(cc1)C(NC(=O)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2)c1ccc(F)cc1 |TLB:11:12:15:19.18.17,THB:20:12:15:19.18.17,20:18:15:34.13.12,21:18:15:34.13.12,13:14:17:34.12.20,13:12:15.14.19:17|			50629014	CHEMBL5408720::US20250353833, Compound 32	Dipeptidyl peptidase 8	Homo sapiens		 667							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629014&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605960	505046986							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578701	Fc1ccc(cc1)C(NC(=O)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2)c1ccc(F)cc1 |TLB:11:12:15:19.18.17,THB:20:12:15:19.18.17,20:18:15:34.13.12,21:18:15:34.13.12,13:14:17:34.12.20,13:12:15.14.19:17|			50629014	CHEMBL5408720::US20250353833, Compound 32	Dipeptidyl peptidase 8	Homo sapiens		 7.66							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629014&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605960	505046986							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578702	O=C(NC(c1ccccc1)c1ccccc1)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:16:17:20:24.23.22,THB:25:17:20:24.23.22,25:23:20:39.18.17,26:23:20:39.18.17,18:19:22:39.17.25,18:17:20.19.24:22|			50629013	CHEMBL5406353::US20250353833, Compound 33	Dipeptidyl peptidase 8	Homo sapiens		 175							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629013	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629013&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605907	505046985							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578703	O=C(NC(c1ccccc1)c1ccccc1)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:16:17:20:24.23.22,THB:25:17:20:24.23.22,25:23:20:39.18.17,26:23:20:39.18.17,18:19:22:39.17.25,18:17:20.19.24:22|			50629013	CHEMBL5406353::US20250353833, Compound 33	Dipeptidyl peptidase 8	Homo sapiens		 2.52							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629013	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629013&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605907	505046985							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578704	O=C(NCCCC[C@H](NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2)C(=O)O)OCc1ccccc1			789086	UAMC-000-4060::US20250353833, Compound 34	Dipeptidyl peptidase 8	Homo sapiens		 9.06							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789086	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789086&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578705	O=C(NCCCC[C@H](NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2)C(=O)O)OCc1ccccc1			789086	UAMC-000-4060::US20250353833, Compound 34	Dipeptidyl peptidase 8	Homo sapiens		 1.74							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789086	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789086&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578706	O[C@H]1CC[C@@H](CC1)NC(=O)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |r,wU:4.7,wD:1.0,TLB:10:11:14:18.17.16,THB:19:11:14:18.17.16,19:17:14:33.12.11,20:17:14:33.12.11,12:13:16:33.11.19,12:11:14.13.18:16,(6.23,-4.67,;4.74,-5.07,;3.65,-3.98,;2.15,-4.38,;1.75,-5.87,;2.85,-6.96,;4.34,-6.56,;.26,-6.27,;-.83,-5.18,;-.43,-3.68,;-2.32,-5.58,;-3.41,-4.48,;-4.45,-4.97,;-5.16,-4.18,;-6.23,-3.98,;-5.08,-3.55,;-4.62,-2.61,;-3.63,-2.73,;-4.66,-3.18,;-2.93,-3.53,;-2.29,-1.96,;-2.29,-.42,;-.96,.35,;.38,-.42,;-.96,1.9,;.27,2.78,;-.2,4.28,;.57,5.63,;-.21,6.96,;-1.74,6.96,;-2.51,5.62,;-1.75,4.28,;-2.21,2.82,;-4.4,-4.27,)|			50629002	CHEMBL5405991::US20250353833, Compound 35	Dipeptidyl peptidase 8	Homo sapiens		 399							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629002	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629002&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605877	505046974							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578707	O[C@H]1CC[C@@H](CC1)NC(=O)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |r,wU:4.7,wD:1.0,TLB:10:11:14:18.17.16,THB:19:11:14:18.17.16,19:17:14:33.12.11,20:17:14:33.12.11,12:13:16:33.11.19,12:11:14.13.18:16,(6.23,-4.67,;4.74,-5.07,;3.65,-3.98,;2.15,-4.38,;1.75,-5.87,;2.85,-6.96,;4.34,-6.56,;.26,-6.27,;-.83,-5.18,;-.43,-3.68,;-2.32,-5.58,;-3.41,-4.48,;-4.45,-4.97,;-5.16,-4.18,;-6.23,-3.98,;-5.08,-3.55,;-4.62,-2.61,;-3.63,-2.73,;-4.66,-3.18,;-2.93,-3.53,;-2.29,-1.96,;-2.29,-.42,;-.96,.35,;.38,-.42,;-.96,1.9,;.27,2.78,;-.2,4.28,;.57,5.63,;-.21,6.96,;-1.74,6.96,;-2.51,5.62,;-1.75,4.28,;-2.21,2.82,;-4.4,-4.27,)|			50629002	CHEMBL5405991::US20250353833, Compound 35	Dipeptidyl peptidase 8	Homo sapiens		 7.31							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629002	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629002&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605877	505046974							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578708	O=C(NCc1ccccc1)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:10:11:14:18.17.16,THB:19:11:14:18.17.16,19:17:14:33.12.11,20:17:14:33.12.11,12:13:16:33.11.19,12:11:14.13.18:16|			50629007	CHEMBL5404995::US20250353833, Compound 36	Dipeptidyl peptidase 8	Homo sapiens		 1150							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629007	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629007&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605938	505046979							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578709	O=C(NCc1ccccc1)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:10:11:14:18.17.16,THB:19:11:14:18.17.16,19:17:14:33.12.11,20:17:14:33.12.11,12:13:16:33.11.19,12:11:14.13.18:16|			50629007	CHEMBL5404995::US20250353833, Compound 36	Dipeptidyl peptidase 8	Homo sapiens		 73.8							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629007	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629007&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605938	505046979							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578710	O=C(NCc1ccncc1)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:10:11:14:18.17.16,THB:19:11:14:18.17.16,19:17:14:33.12.11,20:17:14:33.12.11,12:13:16:33.11.19,12:11:14.13.18:16|			50629009	CHEMBL5438110::US20250353833, Compound 37	Dipeptidyl peptidase 8	Homo sapiens		 1110							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629009	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629009&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605878	505046981							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578711	O=C(NCc1ccncc1)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:10:11:14:18.17.16,THB:19:11:14:18.17.16,19:17:14:33.12.11,20:17:14:33.12.11,12:13:16:33.11.19,12:11:14.13.18:16|			50629009	CHEMBL5438110::US20250353833, Compound 37	Dipeptidyl peptidase 8	Homo sapiens		 90.8							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629009	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629009&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605878	505046981							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578712	O=C(NCCCc1ccccc1)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:12:13:16:20.19.18,THB:21:13:16:20.19.18,21:19:16:35.14.13,22:19:16:35.14.13,14:15:18:35.13.21,14:13:16.15.20:18|			50629012	CHEMBL5422425::US20250353833, Compound 38	Dipeptidyl peptidase 8	Homo sapiens		 1010							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629012	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629012&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172456730	505046984							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578713	O=C(NCCCc1ccccc1)OC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:12:13:16:20.19.18,THB:21:13:16:20.19.18,21:19:16:35.14.13,22:19:16:35.14.13,14:15:18:35.13.21,14:13:16.15.20:18|			50629012	CHEMBL5422425::US20250353833, Compound 38	Dipeptidyl peptidase 8	Homo sapiens		 3.79							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629012	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629012&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172456730	505046984							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578714	Fc1ccc(CNC(=O)OC23CC4CC(CC(C4)(C2)NCC(=O)N2Cc4ccccc4C2)C3)c(F)c1 |TLB:9:10:13:17.16.15,THB:18:10:13:17.16.15,18:16:13:32.11.10,19:16:13:32.11.10,11:12:15:32.10.18,11:10:13.12.17:15|			50629008	CHEMBL5401877::US20250353833, Compound 39	Dipeptidyl peptidase 8	Homo sapiens		 823							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629008	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629008&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172444496	505046980							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578715	Fc1ccc(CNC(=O)OC23CC4CC(CC(C4)(C2)NCC(=O)N2Cc4ccccc4C2)C3)c(F)c1 |TLB:9:10:13:17.16.15,THB:18:10:13:17.16.15,18:16:13:32.11.10,19:16:13:32.11.10,11:12:15:32.10.18,11:10:13.12.17:15|			50629008	CHEMBL5401877::US20250353833, Compound 39	Dipeptidyl peptidase 8	Homo sapiens		 6.03							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629008	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629008&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172444496	505046980							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578716	CC(C)(C)NC(=O)NC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:7:8:11:15.14.13,THB:16:8:11:15.14.13,16:14:11:30.9.8,17:14:11:30.9.8,9:10:13:30.8.16,9:8:11.10.15:13|			50629027	CHEMBL5403872::US20250353833, Compound 40	Dipeptidyl peptidase 8	Homo sapiens		 1050							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629027&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172444051	505046999							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578717	CC(C)(C)NC(=O)NC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:7:8:11:15.14.13,THB:16:8:11:15.14.13,16:14:11:30.9.8,17:14:11:30.9.8,9:10:13:30.8.16,9:8:11.10.15:13|			50629027	CHEMBL5403872::US20250353833, Compound 40	Dipeptidyl peptidase 8	Homo sapiens		 51.8							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629027&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172444051	505046999							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578718	O=C(CNC12CC3CC(C1)CC(C3)(C2)NC(=O)NC12CC3CC(CC(C3)C1)C2)N1Cc2ccccc2C1 |TLB:14:11:7:5.4.9,12:11:7.6.5:9,21:22:19.20.25:26,THB:13:11:7:5.4.9,13:4:7:10.12.11,23:22:19:25.24.26,23:24:19:27.21.22,3:4:7:10.12.11,12:6:9:10.11.13,21:20:26:27.22.23|			50629030	CHEMBL5400525::US20250353833, Compound 41	Dipeptidyl peptidase 8	Homo sapiens		 592							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629030	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629030&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172440017	505047002							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578719	O=C(CNC12CC3CC(C1)CC(C3)(C2)NC(=O)NC12CC3CC(CC(C3)C1)C2)N1Cc2ccccc2C1 |TLB:14:11:7:5.4.9,12:11:7.6.5:9,21:22:19.20.25:26,THB:13:11:7:5.4.9,13:4:7:10.12.11,23:22:19:25.24.26,23:24:19:27.21.22,3:4:7:10.12.11,12:6:9:10.11.13,21:20:26:27.22.23|			50629030	CHEMBL5400525::US20250353833, Compound 41	Dipeptidyl peptidase 8	Homo sapiens		 1.05							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629030	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629030&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172440017	505047002							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578720	O=C(CNC12CC3CC(C1)CC(C3)(C2)NC(=O)NCc1ccccc1)N1Cc2ccccc2C1 |TLB:14:11:7:5.4.9,12:11:7.6.5:9,THB:13:11:7:5.4.9,13:4:7:10.12.11,3:4:7:10.12.11,12:6:9:10.11.13|			50629031	CHEMBL5437013::US20250353833, Compound 42	Dipeptidyl peptidase 8	Homo sapiens		 505							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629031&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170606012	505047003							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578721	O=C(CNC12CC3CC(C1)CC(C3)(C2)NC(=O)NCc1ccccc1)N1Cc2ccccc2C1 |TLB:14:11:7:5.4.9,12:11:7.6.5:9,THB:13:11:7:5.4.9,13:4:7:10.12.11,3:4:7:10.12.11,12:6:9:10.11.13|			50629031	CHEMBL5437013::US20250353833, Compound 42	Dipeptidyl peptidase 8	Homo sapiens		 37.8							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629031&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170606012	505047003							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578722	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2)C1C2CC3CC(C2)CC1C3			789095	UAMC-000-4151::US20250353833, Compound 43	Dipeptidyl peptidase 8	Homo sapiens		 5700							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789095	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789095&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578723	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2)C1C2CC3CC(C2)CC1C3			789095	UAMC-000-4151::US20250353833, Compound 43	Dipeptidyl peptidase 8	Homo sapiens		 186							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789095	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789095&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578724	O=C(CCc1ccc(cc1)C#N)NC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:12:13:16:20.19.18,THB:21:13:16:20.19.18,21:19:16:35.14.13,22:19:16:35.14.13,14:15:18:35.13.21,14:13:16.15.20:18|			50629036	CHEMBL5401924::US20250353833, Compound 44	Dipeptidyl peptidase 8	Homo sapiens		 638							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629036	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629036&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605860	505047008							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578725	O=C(CCc1ccc(cc1)C#N)NC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccccc3C1)C2 |TLB:12:13:16:20.19.18,THB:21:13:16:20.19.18,21:19:16:35.14.13,22:19:16:35.14.13,14:15:18:35.13.21,14:13:16.15.20:18|			50629036	CHEMBL5401924::US20250353833, Compound 44	Dipeptidyl peptidase 8	Homo sapiens		 1.80							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629036	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629036&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605860	505047008							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578726	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)C1C2CC3CC(C2)CC1C3			789097	UAMC-000-4290::US20250353833, Compound 45	Dipeptidyl peptidase 8	Homo sapiens		 1176							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789097	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789097&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578727	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)C1C2CC3CC(C2)CC1C3			789097	UAMC-000-4290::US20250353833, Compound 45	Dipeptidyl peptidase 8	Homo sapiens		 38.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789097	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789097&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578728	CC(C)(C)OC(=O)NC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccc(F)cc3C1)C2 |TLB:7:8:11:15.14.13,THB:16:8:11:15.14.13,16:14:11:31.9.8,17:14:11:31.9.8,9:10:13:31.8.16,9:8:11.10.15:13|			50629022	CHEMBL5421476::US20250353833, Compound 46	Dipeptidyl peptidase 8	Homo sapiens		 824							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629022	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629022&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172455865	505046994							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578729	CC(C)(C)OC(=O)NC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccc(F)cc3C1)C2 |TLB:7:8:11:15.14.13,THB:16:8:11:15.14.13,16:14:11:31.9.8,17:14:11:31.9.8,9:10:13:31.8.16,9:8:11.10.15:13|			50629022	CHEMBL5421476::US20250353833, Compound 46	Dipeptidyl peptidase 8	Homo sapiens		 2.44							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629022	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629022&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172455865	505046994							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578730	NC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1Cc2ccc(F)cc2C1 |TLB:0:1:4:7.8.9,6:1:4.5.7:9,THB:10:1:4:7.8.9,10:8:4:2.6.1,11:8:4:2.6.1,6:5:9:2.1.10|			50628989	CHEMBL5433274::US20250353833, Compound 47	Dipeptidyl peptidase 8	Homo sapiens		 2620							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628989	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628989&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172463369	505046961							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578731	NC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1Cc2ccc(F)cc2C1 |TLB:0:1:4:7.8.9,6:1:4.5.7:9,THB:10:1:4:7.8.9,10:8:4:2.6.1,11:8:4:2.6.1,6:5:9:2.1.10|			50628989	CHEMBL5433274::US20250353833, Compound 47	Dipeptidyl peptidase 8	Homo sapiens		 259							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628989	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628989&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172463369	505046961							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578732	CC(C)(C)NC(=O)NC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccc(F)cc3C1)C2 |TLB:7:8:11:15.14.13,THB:16:8:11:15.14.13,16:14:11:31.9.8,17:14:11:31.9.8,9:10:13:31.8.16,9:8:11.10.15:13|			50629028	CHEMBL5398643::US20250353833, Compound 48	Dipeptidyl peptidase 8	Homo sapiens		 369							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629028	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629028&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172440470	505047000							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578733	CC(C)(C)NC(=O)NC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3ccc(F)cc3C1)C2 |TLB:7:8:11:15.14.13,THB:16:8:11:15.14.13,16:14:11:31.9.8,17:14:11:31.9.8,9:10:13:31.8.16,9:8:11.10.15:13|			50629028	CHEMBL5398643::US20250353833, Compound 48	Dipeptidyl peptidase 8	Homo sapiens		 4.00							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629028	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629028&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172440470	505047000							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578734	CC(C)(C)OC(=O)NC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3cc(F)c(F)cc3C1)C2 |TLB:7:8:11:15.14.13,THB:16:8:11:15.14.13,16:14:11:32.9.8,17:14:11:32.9.8,9:10:13:32.8.16,9:8:11.10.15:13|			50629023	CHEMBL5402430::US20250353833, Compound 49	Dipeptidyl peptidase 8	Homo sapiens		 613							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629023	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629023&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172439227	505046995							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578735	CC(C)(C)OC(=O)NC12CC3CC(CC(C3)(C1)NCC(=O)N1Cc3cc(F)c(F)cc3C1)C2 |TLB:7:8:11:15.14.13,THB:16:8:11:15.14.13,16:14:11:32.9.8,17:14:11:32.9.8,9:10:13:32.8.16,9:8:11.10.15:13|			50629023	CHEMBL5402430::US20250353833, Compound 49	Dipeptidyl peptidase 8	Homo sapiens		 3.40							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629023	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629023&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			172439227	505046995							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578736	O=C([O-])[C@@H]1CCCN1C(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789104	UAMC-000-4913::US20250353833, Compound 50	Dipeptidyl peptidase 8	Homo sapiens		 920							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789104	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789104&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578737	O=C([O-])[C@@H]1CCCN1C(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789104	UAMC-000-4913::US20250353833, Compound 50	Dipeptidyl peptidase 8	Homo sapiens		 8.03							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789104	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789104&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578738	CC(C)C[C@H](NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)C(=O)[O-]			789105	UAMC-000-4912::US20250353833, Compound 51	Dipeptidyl peptidase 8	Homo sapiens		 1080							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789105	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789105&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578739	CC(C)C[C@H](NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)C(=O)[O-]			789105	UAMC-000-4912::US20250353833, Compound 51	Dipeptidyl peptidase 8	Homo sapiens		 2.79							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789105	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789105&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578740	CSCC[C@H](NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)C(=O)[O-]			789106	UAMC-000-4911::US20250353833, Compound 52	Dipeptidyl peptidase 8	Homo sapiens		 504							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789106	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789106&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578741	CSCC[C@H](NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)C(=O)[O-]			789106	UAMC-000-4911::US20250353833, Compound 52	Dipeptidyl peptidase 8	Homo sapiens		 9.13							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789106	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789106&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578742	O=C([O-])CNC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789107	UAMC-000-4909::US20250353833, Compound 53	Dipeptidyl peptidase 8	Homo sapiens		 1740							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789107	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789107&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578743	O=C([O-])CNC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789107	UAMC-000-4909::US20250353833, Compound 53	Dipeptidyl peptidase 8	Homo sapiens		 4.70							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789107	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789107&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578744	NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789108	UAMC-000-4801::US20250353833, Compound 54	Dipeptidyl peptidase 8	Homo sapiens		 243							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789108	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789108&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578745	NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789108	UAMC-000-4801::US20250353833, Compound 54	Dipeptidyl peptidase 8	Homo sapiens		 8.88							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789108	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789108&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578746	O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)[O-])OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789109	UAMC-000-4910::US20250353833, Compound 55	Dipeptidyl peptidase 8	Homo sapiens		 4.37							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789109	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789109&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578747	O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)[O-])OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789109	UAMC-000-4910::US20250353833, Compound 55	Dipeptidyl peptidase 8	Homo sapiens		 6.55							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789109	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789109&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578748	CC[C@H](C)[C@H](NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)C(=O)OC			789110	UAMC-000-4798::US20250353833, Compound 56	Dipeptidyl peptidase 8	Homo sapiens		 2080							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789110	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789110&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578749	CC[C@H](C)[C@H](NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)C(=O)OC			789110	UAMC-000-4798::US20250353833, Compound 56	Dipeptidyl peptidase 8	Homo sapiens		 2.29							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789110	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789110&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578750	COC(=O)[C@@H](NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)C(C)C			789111	UAMC-000-4796::US20250353833, Compound 57	Dipeptidyl peptidase 8	Homo sapiens		 2180							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789111	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789111&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578751	COC(=O)[C@@H](NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)C(C)C			789111	UAMC-000-4796::US20250353833, Compound 57	Dipeptidyl peptidase 8	Homo sapiens		 1.72							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789111	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789111&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578752	COc1ccc2c(c1)CN(C(=O)CNC13CC4CC(C1)CC(NC(=O)OC(C)(C)C)(C4)C3)C2			789112	UAMC-000-4927::US20250353833, Compound 59	Dipeptidyl peptidase 8	Homo sapiens		 5220							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789112	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789112&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578753	COc1ccc2c(c1)CN(C(=O)CNC13CC4CC(C1)CC(NC(=O)OC(C)(C)C)(C4)C3)C2			789112	UAMC-000-4927::US20250353833, Compound 59	Dipeptidyl peptidase 8	Homo sapiens		 309							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789112	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789112&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578754	COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789115	UAMC-000-4800::US20250353833, Compound 60	Dipeptidyl peptidase 8	Homo sapiens		 689							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789115	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789115&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578755	COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789115	UAMC-000-4800::US20250353833, Compound 60	Dipeptidyl peptidase 8	Homo sapiens		 4.71							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789115	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789115&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578756	COC(=O)[C@H](CCSC)NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789116	UAMC-000-4794::US20250353833, Compound 61	Dipeptidyl peptidase 8	Homo sapiens		 705							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789116	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789116&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578757	COC(=O)[C@H](CCSC)NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789116	UAMC-000-4794::US20250353833, Compound 61	Dipeptidyl peptidase 8	Homo sapiens		 6.12							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789116	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789116&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578758	COC(=O)[C@H](C)NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789117	UAMC-000-4797::US20250353833, Compound 62	Dipeptidyl peptidase 8	Homo sapiens		 1290							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789117	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789117&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578759	COC(=O)[C@H](C)NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789117	UAMC-000-4797::US20250353833, Compound 62	Dipeptidyl peptidase 8	Homo sapiens		 93.8							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789117	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789117&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578760	CC12CC3CC(C)(C1)CC(NCC(=O)N1Cc4ccc(F)cc4C1)(C3)C2			789118	UAMC-000-4803::US20250353833, Compound 63	Dipeptidyl peptidase 8	Homo sapiens		 4780							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789118	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789118&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578761	CC12CC3CC(C)(C1)CC(NCC(=O)N1Cc4ccc(F)cc4C1)(C3)C2			789118	UAMC-000-4803::US20250353833, Compound 63	Dipeptidyl peptidase 8	Homo sapiens		 443							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789118	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789118&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578762	O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCOC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			50634823	CHEMBL5558218::US20250353833, Compound 73	Dipeptidyl peptidase 8	Homo sapiens		 457							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634823&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605934	519655226							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578763	O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCOC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			50634823	CHEMBL5558218::US20250353833, Compound 73	Dipeptidyl peptidase 8	Homo sapiens		 16.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634823&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605934	519655226							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578764	O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCNC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			50634824	CHEMBL5505931::US20250353833, Compound 74	Dipeptidyl peptidase 8	Homo sapiens		 310							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634824&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605892	519655227							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578765	O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCNC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			50634824	CHEMBL5505931::US20250353833, Compound 74	Dipeptidyl peptidase 8	Homo sapiens		 19.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634824&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605892	519655227							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578766	O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCOCCOCCNC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789126	UAMC-000-4925::US20250353833, Compound 75	Dipeptidyl peptidase 8	Homo sapiens		 495							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789126	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789126&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578767	O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCOCCOCCNC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2			789126	UAMC-000-4925::US20250353833, Compound 75	Dipeptidyl peptidase 8	Homo sapiens		 43.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789126	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789126&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578768	O=C1CCC(N2C(=O)c3cccc(NCCOCCOC(=O)NC45CC6CC(CC(NCC(=O)N7Cc8ccc(F)cc8C7)(C6)C4)C5)c3C2=O)C(=O)N1			789127	UAMC-000-4923::US20250353833, Compound 76	Dipeptidyl peptidase 8	Homo sapiens		 8.00							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789127	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789127&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578769	O=C1CCC(N2C(=O)c3cccc(NCCOCCOC(=O)NC45CC6CC(CC(NCC(=O)N7Cc8ccc(F)cc8C7)(C6)C4)C5)c3C2=O)C(=O)N1			789127	UAMC-000-4923::US20250353833, Compound 76	Dipeptidyl peptidase 8	Homo sapiens		 1.40							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789127	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789127&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578770	O=C1CCC(N2C(=O)c3cccc(NCCOCCNC(=O)NC45CC6CC(CC(NCC(=O)N7Cc8ccc(F)cc8C7)(C6)C4)C5)c3C2=O)C(=O)N1			789128	UAMC-000-4921::US20250353833, Compound 77	Dipeptidyl peptidase 8	Homo sapiens		 21.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789128	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789128&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578771	O=C1CCC(N2C(=O)c3cccc(NCCOCCNC(=O)NC45CC6CC(CC(NCC(=O)N7Cc8ccc(F)cc8C7)(C6)C4)C5)c3C2=O)C(=O)N1			789128	UAMC-000-4921::US20250353833, Compound 77	Dipeptidyl peptidase 8	Homo sapiens		 2.40							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789128	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789128&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578772	O=C1CCC(N2C(=O)c3cccc(NCCOCCOCCOCCNC(=O)NC45CC6CC(CC(NCC(=O)N7Cc8ccc(F)cc8C7)(C6)C4)C5)c3C2=O)C(=O)N1			789129	UAMC-000-4922::US20250353833, Compound 78	Dipeptidyl peptidase 8	Homo sapiens		 79.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789129	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789129&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578773	O=C1CCC(N2C(=O)c3cccc(NCCOCCOCCOCCNC(=O)NC45CC6CC(CC(NCC(=O)N7Cc8ccc(F)cc8C7)(C6)C4)C5)c3C2=O)C(=O)N1			789129	UAMC-000-4922::US20250353833, Compound 78	Dipeptidyl peptidase 8	Homo sapiens		 12.0							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789129	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789129&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578774	Cc1ccc2c(c1)CN(C(=O)CNC13CC4CC(C1)CC(NC(=O)OC(C)(C)C)(C4)C3)C2			789136	UAMC-000-5033::US20250353833, Inhibitor NF-2022-071	Dipeptidyl peptidase 8	Homo sapiens		 4.71							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789136	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789136&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578775	Cc1ccc2c(c1)CN(C(=O)CNC13CC4CC(C1)CC(NC(=O)OC(C)(C)C)(C4)C3)C2			789136	UAMC-000-5033::US20250353833, Inhibitor NF-2022-071	Dipeptidyl peptidase 9	Homo sapiens		 0.208							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789136	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789136&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578776	CC(C)(C)NC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2			789137	UAMC-000-5036::US20250353833, Inhibitor UAMC0005036	Dipeptidyl peptidase 8	Homo sapiens		 1.33							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789137	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789137&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578777	CC(C)(C)NC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2			789137	UAMC-000-5036::US20250353833, Inhibitor UAMC0005036	Dipeptidyl peptidase 9	Homo sapiens		 0.006							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789137	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789137&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578778	CC(C)(C)CC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2			789138	UAMC-000-50 37::US20250353833, Inhibitor UAMC0005037	Dipeptidyl peptidase 8	Homo sapiens		 1.30							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789138	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789138&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578779	CC(C)(C)CC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2			789138	UAMC-000-50 37::US20250353833, Inhibitor UAMC0005037	Dipeptidyl peptidase 9	Homo sapiens		 0.006							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789138	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789138&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578780	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccccc2)cc1			789139	UAMC-000-5035::US20250353833, Inhibitor UAMC0005035	Dipeptidyl peptidase 8	Homo sapiens		 0.276							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789139	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789139&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578781	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccccc2)cc1			789139	UAMC-000-5035::US20250353833, Inhibitor UAMC0005035	Dipeptidyl peptidase 9	Homo sapiens		 0.005							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789139	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789139&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578782	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2cccnc2)cc1			789140	UAMC-000-5111::US20250353833, Inhibitor UAMC0005111	Dipeptidyl peptidase 8	Homo sapiens		 0.051							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789140	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789140&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578783	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2cccnc2)cc1			789140	UAMC-000-5111::US20250353833, Inhibitor UAMC0005111	Dipeptidyl peptidase 9	Homo sapiens		 0.002							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789140	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789140&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578784	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccccc2)nc1			789141	UAMC-000-5112::US20250353833, Inhibitor NF-2023-048	Dipeptidyl peptidase 8	Homo sapiens		 0.145							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789141	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789141&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578785	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccccc2)nc1			789141	UAMC-000-5112::US20250353833, Inhibitor NF-2023-048	Dipeptidyl peptidase 9	Homo sapiens		 0.005							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789141	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789141&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578786	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccccn2)cc1			789142	UAMC-000-5113::US20250353833, Inhibitor NF-2023-069	Dipeptidyl peptidase 8	Homo sapiens		 0.127							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789142	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789142&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578787	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccccn2)cc1			789142	UAMC-000-5113::US20250353833, Inhibitor NF-2023-069	Dipeptidyl peptidase 9	Homo sapiens		 0.003							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789142	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789142&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578788	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccncc2)cc1			789143	UAMC-000-5114::US20250353833, Inhibitor UAMC-0005114	Dipeptidyl peptidase 8	Homo sapiens		 0.102							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789143	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789143&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578789	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccncc2)cc1			789143	UAMC-000-5114::US20250353833, Inhibitor UAMC-0005114	Dipeptidyl peptidase 9	Homo sapiens		 0.008							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789143	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789143&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578790	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2cccs2)cc1			789144	UAMC-000-5116::US20250353833, Inhibitor NF-2023-049	Dipeptidyl peptidase 8	Homo sapiens		 0.222							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789144	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789144&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578791	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2cccs2)cc1			789144	UAMC-000-5116::US20250353833, Inhibitor NF-2023-049	Dipeptidyl peptidase 9	Homo sapiens		 0.008							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789144	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789144&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578792	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccc(F)cc2)cc1			789146	UAMC-000-5356::US20250353833, Inhibitor NF-2023-050	Dipeptidyl peptidase 8	Homo sapiens		 0.757							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789146	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789146&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578793	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccc(F)cc2)cc1			789146	UAMC-000-5356::US20250353833, Inhibitor NF-2023-050	Dipeptidyl peptidase 9	Homo sapiens		 0.001							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789146	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789146&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578794	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccccc2F)cc1			789147	UAMC-000-5357::US20250353833, Inhibitor NF-2023-051	Dipeptidyl peptidase 8	Homo sapiens		 0.403							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789147	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789147&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578795	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccccc2F)cc1			789147	UAMC-000-5357::US20250353833, Inhibitor NF-2023-051	Dipeptidyl peptidase 9	Homo sapiens		 0.002							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789147	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789147&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578796	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(F)cc1			789149	UAMC-000-5359::US20250353833, Inhibitor NF-2023-053	Dipeptidyl peptidase 8	Homo sapiens		 0.295							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789149	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789149&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578797	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(F)cc1			789149	UAMC-000-5359::US20250353833, Inhibitor NF-2023-053	Dipeptidyl peptidase 9	Homo sapiens		 0.007							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789149	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789149&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578798	N#Cc1ccc(C(=O)NC23CC4CC(CC(NCC(=O)N5Cc6ccc(F)cc6C5)(C4)C2)C3)cc1			789155	UAMC-000-5360::US20250353833, Inhibitor NF-2023-054	Dipeptidyl peptidase 8	Homo sapiens		 0.161							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789155	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789155&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578799	N#Cc1ccc(C(=O)NC23CC4CC(CC(NCC(=O)N5Cc6ccc(F)cc6C5)(C4)C2)C3)cc1			789155	UAMC-000-5360::US20250353833, Inhibitor NF-2023-054	Dipeptidyl peptidase 9	Homo sapiens		 0.001							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789155	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789155&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578800	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccccc2)s1			789156	UAMC-000-5361::US20250353833, Inhibitor NF-2023-055	Dipeptidyl peptidase 8	Homo sapiens		 0.244							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789156	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789156&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578801	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccccc2)s1			789156	UAMC-000-5361::US20250353833, Inhibitor NF-2023-055	Dipeptidyl peptidase 9	Homo sapiens		 0.002							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789156	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789156&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578802	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1cccnc1			789159	UAMC-000-5363::US20250353833, Inhibitor NF-2023-057	Dipeptidyl peptidase 8	Homo sapiens		 0.270							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789159	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789159&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578803	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1cccnc1			789159	UAMC-000-5363::US20250353833, Inhibitor NF-2023-057	Dipeptidyl peptidase 9	Homo sapiens		 0.088							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789159	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789159&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578804	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1cnc2ccccc2c1			789160	UAMC-000-5364::US20250353833, Inhibitor NF-2023-058	Dipeptidyl peptidase 8	Homo sapiens		 0.001							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789160	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789160&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578805	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1cnc2ccccc2c1			789160	UAMC-000-5364::US20250353833, Inhibitor NF-2023-058	Dipeptidyl peptidase 9	Homo sapiens		 0.003							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789160	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789160&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578806	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2cccs2)nc1			789162	UAMC-000-5365::US20250353833, Inhibitor NF-2023-059	Dipeptidyl peptidase 8	Homo sapiens		 0.117							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789162	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789162&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578807	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2cccs2)nc1			789162	UAMC-000-5365::US20250353833, Inhibitor NF-2023-059	Dipeptidyl peptidase 9	Homo sapiens		 0.005							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789162	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789162&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578808	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1cccc(-c2ccccc2)c1			789163	UAMC-000-5366::US20250353833, Inhibitor NF-2023-060	Dipeptidyl peptidase 8	Homo sapiens		 0.006							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789163	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789163&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578809	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1cccc(-c2ccccc2)c1			789163	UAMC-000-5366::US20250353833, Inhibitor NF-2023-060	Dipeptidyl peptidase 9	Homo sapiens		 0.004							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789163	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789163&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578810	O=C(CNC12CC3CC(C1)CC(NS(=O)(=O)c1ccc(-c4ccccc4)cc1)(C3)C2)N1Cc2ccc(F)cc2C1			789164	UAMC-000-5444::US20250353833, Inhibitor UAMC-0005444	Dipeptidyl peptidase 8	Homo sapiens		 5.12							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789164	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789164&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578811	O=C(CNC12CC3CC(C1)CC(NS(=O)(=O)c1ccc(-c4ccccc4)cc1)(C3)C2)N1Cc2ccc(F)cc2C1			789164	UAMC-000-5444::US20250353833, Inhibitor UAMC-0005444	Dipeptidyl peptidase 9	Homo sapiens		 1.25							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789164	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789164&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578812	COC(=O)c1csc(-c2ccc(C(=O)NC34CC5CC(CC(NCC(=O)N6Cc7ccc(F)cc7C6)(C5)C3)C4)cc2)c1			789165	UAMC-000-5377::US20250353833, Inhibitor MFE-2022-192	Dipeptidyl peptidase 8	Homo sapiens		 0.005							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789165	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789165&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578813	COC(=O)c1csc(-c2ccc(C(=O)NC34CC5CC(CC(NCC(=O)N6Cc7ccc(F)cc7C6)(C5)C3)C4)cc2)c1			789165	UAMC-000-5377::US20250353833, Inhibitor MFE-2022-192	Dipeptidyl peptidase 9	Homo sapiens		 0.002							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789165	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789165&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578814	COC(=O)c1ccc(-c2ccc(C(=O)NC34CC5CC(CC(NCC(=O)N6Cc7ccc(F)cc7C6)(C5)C3)C4)cc2)cc1			789167	UAMC-000-5376::US20250353833, Inhibitor MFE-2022-186	Dipeptidyl peptidase 8	Homo sapiens		 0.005							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789167	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789167&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578815	COC(=O)c1ccc(-c2ccc(C(=O)NC34CC5CC(CC(NCC(=O)N6Cc7ccc(F)cc7C6)(C5)C3)C4)cc2)cc1			789167	UAMC-000-5376::US20250353833, Inhibitor MFE-2022-186	Dipeptidyl peptidase 9	Homo sapiens		 0.001							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789167	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789167&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578816	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccc(O)cc2)cc1			789168	UAMC-000-5378::US20250353833, Inhibitor MFE-2022-203	Dipeptidyl peptidase 8	Homo sapiens		 0.476							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789168	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789168&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578817	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccc(O)cc2)cc1			789168	UAMC-000-5378::US20250353833, Inhibitor MFE-2022-203	Dipeptidyl peptidase 9	Homo sapiens		 0.001							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789168	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789168&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578818	O=C(CNC12CC3CC(C1)CC(Nc1ccc(-c4ccccc4)nc1)(C3)C2)N1Cc2ccc(F)cc2C1			789169	UAMC-000-5379::US20250353833, Inhibitor MFE-2022-212	Dipeptidyl peptidase 8	Homo sapiens		 0.009							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789169	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789169&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578819	O=C(CNC12CC3CC(C1)CC(Nc1ccc(-c4ccccc4)nc1)(C3)C2)N1Cc2ccc(F)cc2C1			789169	UAMC-000-5379::US20250353833, Inhibitor MFE-2022-212	Dipeptidyl peptidase 9	Homo sapiens		 0.006							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789169	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789169&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578820	O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCNC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2			50634827	CHEMBL5558204::US20250353833, Inhibitor MFE-2022-119	Dipeptidyl peptidase 8	Homo sapiens		 0.541							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634827	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634827&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			175969780	519655230							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578821	O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCNC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2			50634827	CHEMBL5558204::US20250353833, Inhibitor MFE-2022-119	Dipeptidyl peptidase 9	Homo sapiens		 0.050							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634827	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634827&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search			175969780	519655230							1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578822	O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCOC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2			50634826	CHEMBL5555956::US20250353833, Inhibitor MFE-2022-122	Dipeptidyl peptidase 8	Homo sapiens		 0.876							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634826	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634826&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			175969840	519655229							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578823	O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCOC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2			50634826	CHEMBL5555956::US20250353833, Inhibitor MFE-2022-122	Dipeptidyl peptidase 9	Homo sapiens		 0.004							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634826	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634826&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search			175969840	519655229							1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578824	O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCOCCOCCNC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2			789172	UAMC-000-5032::US20250353833, Inhibitor MFE-2022-124	Dipeptidyl peptidase 8	Homo sapiens		 0.812							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789172	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789172&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578825	O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCOCCOCCNC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2			789172	UAMC-000-5032::US20250353833, Inhibitor MFE-2022-124	Dipeptidyl peptidase 9	Homo sapiens		 0.113							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789172	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789172&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578826	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2)OCCOCCNc1ccc([N+](=O)[O-])c2nonc12			50634819	CHEMBL5527979::US20250353833, Inhibitor MFE-2022-109	Dipeptidyl peptidase 8	Homo sapiens		 0.210							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634819&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605998	519655222							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578827	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2)OCCOCCNc1ccc([N+](=O)[O-])c2nonc12			50634819	CHEMBL5527979::US20250353833, Inhibitor MFE-2022-109	Dipeptidyl peptidase 9	Homo sapiens		 0.004							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634819&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search			170605998	519655222							1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578828	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2)OCCOCCNc1ccc([N+](=O)[O-])c2nonc12			50634819	CHEMBL5527979::US20250353833, Inhibitor MFE-2022-109	Dipeptidyl peptidase 8	Homo sapiens		 0.418							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634819&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605998	519655222							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578829	O=C(NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2)OCCOCCNc1ccc([N+](=O)[O-])c2nonc12			50634819	CHEMBL5527979::US20250353833, Inhibitor MFE-2022-109	Dipeptidyl peptidase 9	Homo sapiens		 0.002							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634819&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search			170605998	519655222							1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578830	CN(C)c1cccc2c(S(=O)(=O)NCCOCCOC(=O)NC34CC5CC(CC(NCC(=O)N6Cc7ccc(F)cc7C6)(C5)C3)C4)cccc12			50634820	CHEMBL5559023::US20250353833, Inhibitor MFE-2022-101	Dipeptidyl peptidase 8	Homo sapiens		 0.066							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634820&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			174307716	519655223							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578831	CN(C)c1cccc2c(S(=O)(=O)NCCOCCOC(=O)NC34CC5CC(CC(NCC(=O)N6Cc7ccc(F)cc7C6)(C5)C3)C4)cccc12			50634820	CHEMBL5559023::US20250353833, Inhibitor MFE-2022-101	Dipeptidyl peptidase 9	Homo sapiens		 0.004							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634820&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search			174307716	519655223							1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578832	CN(C)c1cccc2c(S(=O)(=O)NCCOCCOC(=O)NC34CC5CC(CC(NCC(=O)N6Cc7cc(F)c(F)cc7C6)(C5)C3)C4)cccc12			50634821	CHEMBL5555335::US20250353833, Inhibitor MFE-2022-114	Dipeptidyl peptidase 8	Homo sapiens		 0.007							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634821	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634821&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			170605941	519655224							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578833	CN(C)c1cccc2c(S(=O)(=O)NCCOCCOC(=O)NC34CC5CC(CC(NCC(=O)N6Cc7cc(F)c(F)cc7C6)(C5)C3)C4)cccc12			50634821	CHEMBL5555335::US20250353833, Inhibitor MFE-2022-114	Dipeptidyl peptidase 9	Homo sapiens		 0.007							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634821	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634821&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search			170605941	519655224							1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578834	CC[N+]1=C(/C=C/C=C2/N(CCCCCC(=O)NC34CC5CC(CC(NCC(=O)N6Cc7ccc(F)cc7C6)(C5)C3)C4)c3ccc(S(=O)(=O)O)cc3C2(C)C)C(C)(C)c2cc(S(=O)(=O)[O-])ccc21			789177	UAMC-000-5156::US20250353833, Inhibitor MFE-2022-126	Dipeptidyl peptidase 8	Homo sapiens		 0.835							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789177	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789177&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578835	CC[N+]1=C(/C=C/C=C2/N(CCCCCC(=O)NC34CC5CC(CC(NCC(=O)N6Cc7ccc(F)cc7C6)(C5)C3)C4)c3ccc(S(=O)(=O)O)cc3C2(C)C)C(C)(C)c2cc(S(=O)(=O)[O-])ccc21			789177	UAMC-000-5156::US20250353833, Inhibitor MFE-2022-126	Dipeptidyl peptidase 9	Homo sapiens		 0.005							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789177	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789177&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578836	CC[N+]1=C(/C=C/C=C2/N(CCCCCC(=O)NC34CC5CC(CC(NCC(=O)N6Cc7cc(F)c(F)cc7C6)(C5)C3)C4)c3ccc(S(=O)(=O)O)cc3C2(C)C)C(C)(C)c2cc(S(=O)(=O)[O-])ccc21			50634822	CHEMBL5558252::US20250353833, Inhibitor MFE-2022-136	Dipeptidyl peptidase 8	Homo sapiens		 1.12							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634822	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634822&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search			177373700	519655225							1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578837	CC[N+]1=C(/C=C/C=C2/N(CCCCCC(=O)NC34CC5CC(CC(NCC(=O)N6Cc7cc(F)c(F)cc7C6)(C5)C3)C4)c3ccc(S(=O)(=O)O)cc3C2(C)C)C(C)(C)c2cc(S(=O)(=O)[O-])ccc21			50634822	CHEMBL5558252::US20250353833, Inhibitor MFE-2022-136	Dipeptidyl peptidase 9	Homo sapiens		 0.054							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634822	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634822&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search			177373700	519655225							1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578838	Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2csc(-c3ccc(C(=O)NC45CC6CC(CC(NCC(=O)N7Cc8ccc(F)cc8C7)(C6)C4)C5)cc3)c2)C(C)(C)C)cc1			789179	UAMC-000-5381::US20250353833, Inhibitor MFE-2022-197	Dipeptidyl peptidase 8	Homo sapiens		 0.793							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789179	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789179&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578839	Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2csc(-c3ccc(C(=O)NC45CC6CC(CC(NCC(=O)N7Cc8ccc(F)cc8C7)(C6)C4)C5)cc3)c2)C(C)(C)C)cc1			789179	UAMC-000-5381::US20250353833, Inhibitor MFE-2022-197	Dipeptidyl peptidase 9	Homo sapiens		 0.070							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789179	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789179&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578840	Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccc(-c3ccc(C(=O)NC45CC6CC(CC(NCC(=O)N7Cc8ccc(F)cc8C7)(C6)C4)C5)cc3)cc2)C(C)(C)C)cc1			789180	UAMC-000-5380::US20250353833, Inhibitor MFE-2022-189	Dipeptidyl peptidase 8	Homo sapiens		 0.008							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789180	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789180&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578841	Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccc(-c3ccc(C(=O)NC45CC6CC(CC(NCC(=O)N7Cc8ccc(F)cc8C7)(C6)C4)C5)cc3)cc2)C(C)(C)C)cc1			789180	UAMC-000-5380::US20250353833, Inhibitor MFE-2022-189	Dipeptidyl peptidase 9	Homo sapiens		 0.173							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789180	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789180&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578842	Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCC(=O)NC23CC4CC(CC(NCC(=O)N5Cc6ccc(F)cc6C5)(C4)C2)C3)C(C)(C)C)cc1			789181	UAMC-000-5215::US20250353833, Inhibitor MFE-2022-147	Dipeptidyl peptidase 8	Homo sapiens		 0.094							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789181	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789181&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578843	Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCC(=O)NC23CC4CC(CC(NCC(=O)N5Cc6ccc(F)cc6C5)(C4)C2)C3)C(C)(C)C)cc1			789181	UAMC-000-5215::US20250353833, Inhibitor MFE-2022-147	Dipeptidyl peptidase 9	Homo sapiens		 0.009							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789181	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789181&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1578844	Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOc2ccc(-c3ccc(C(=O)NC45CC6CC(CC(NCC(=O)N7Cc8ccc(F)cc8C7)(C6)C4)C5)cc3)cc2)C(C)(C)C)cc1			789182	UAMC-000-5382::US20250353833, Inhibitor MFE-2022-217	Dipeptidyl peptidase 8	Homo sapiens		 0.127							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789182	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1236&target=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789182&enzyme=Dipeptidyl+peptidase+8&column=ki&startPg=0&Increment=50&submit=Search											1	MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI	7SVO,6TRX,6TRW,7SVM,7OZ7,7OR4,7AYR,7AYQ,7A3L,7A3K,7A3J,7A3I,7A3G,6QZW,6HP8,6EOT,6EOS,6EOP,6EOO	Dipeptidyl peptidase 8	DPP8_HUMAN	Q6V1X1	Q7Z4C8 Q7Z4D3 Q7Z4E1 Q8IWG7 Q8NEM5 Q96JX1 Q9HBM2 Q9HBM3 Q9HBM4 Q9HBM5 Q9NXF4			N/A	A0A024R5Z6																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1578845	Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOc2ccc(-c3ccc(C(=O)NC45CC6CC(CC(NCC(=O)N7Cc8ccc(F)cc8C7)(C6)C4)C5)cc3)cc2)C(C)(C)C)cc1			789182	UAMC-000-5382::US20250353833, Inhibitor MFE-2022-217	Dipeptidyl peptidase 9	Homo sapiens		 0.001							Curated from the literature by BindingDB						n/a	11/20/2025	3/10/2026	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=789182	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1237&target=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=789182&enzyme=Dipeptidyl+peptidase+9&column=ki&startPg=0&Increment=50&submit=Search											1	MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL	7JN7,7A3F,6X6C,6QZV,7JKQ,6X6A,7SVN,7SVL,6EOR,6EOQ,9GON,9GOD,7ZXS,7CRW	Dipeptidyl peptidase 9	DPP9_HUMAN	Q86TI2	O75273 O75868 Q1ZZB8 Q6AI37 Q6UAL0 Q6ZMT2 Q6ZNJ5 Q8N2J7 Q8N3F5 Q8WXD8 Q96NT8 Q9BVR3