Found 250 of ic50 for monomerid = 1434 TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 0.338nMAssay Description:Inhibition of HIV1 3B reverse transcriptase activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 0.413nMAssay Description:Inhibition of HIV1 3B reverse transcriptase activity infected in human H9 cells assessed as level of p24 antigenMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant wild-type HIV1 3B reverse transcriptase assessed as reduction in biotin-dUTP incorporation using poly(rA)/oligo(dT)16 as te...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 2.60nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
3D Structure (crystal)TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of reverse transcriptase activity in HIV1 infected HeLa-MAGI cells at 37 deg C after 48 hrsMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (P236L)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase in 293T cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1027,P835L]/[600-1155,P835L](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 80nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 80nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 84nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:In vitro for inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of HIV1 reverse transcriptase derived from HIV patient plasma by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibitory activity against HIV-1 Reverse transcriptase(RT) was determinedMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV1 reverse transcriptase using T19-Cy5 labeled 23-mer DNA/T2-TAMRA labeled 63-mer DNA as primer/template assessed as inhibition of dN...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Jaipur National University
Jaipur National University
Affinity DataIC50: >100nMT: 2°CAssay Description:To a lysis buffer (20 μl), 4-6 ng recombinant HIV-1-RT was added in separate reaction tubes. Lysis buffer without HIV-1-RT was used as a negative ...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 101nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 125nMAssay Description:Inhibition of recombinant HIV1 His-tagged p66/p51 reverse transcriptase expressed in Escherichia coli assessed as reduction in [3H]dTTP incorporation...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 137nMAssay Description:Inhibition of HIV1 isolate R8 reverse transcriptase after 90 minsMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of HIV1 RT using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated for 10 m...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of HIV1 RT using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated for 10 m...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 170nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Compound was tested for inhibitory activity against HIV-1 wild type reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 176nMAssay Description:Inhibition of recombinant wild type HIV1 reverse transcriptase p66/p51 using poly (rA)/anoligo (dT)16 as template/primer assessed as inhibition of bi...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of HIV1 reverse transcriptase RNA-dependent DNA polymerase activity assessed as incorporation of radioactive dTTP into poly(rA)/oligo(DT)More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of HIV1 recombinant RNA-dependent DNA polymerase activity of reverse transcriptase assessed as incorporation of radioactive dTTP into poly...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of RNA dependent DNA polymerase activity of HIV1 recombinant reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV1 reverse transcriptase using poly(rA)/pligo(dT) templateMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (K103N)More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 181nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptase assessed as reduction in biotin-dUTP incorporation in to cDNA chain incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 200nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 200nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 200nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibitory effect on wild type HIV- 1 reverse transcriptase using rCdG as template and dGTP as substrate.More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptase incubated for 2 hrs by colorimetric assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibitory concentration against wild-type reverse transcriptase of HIV-1More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of HIV-1 recombinant reverse transcriptaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 270nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 300nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 300nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 300nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Jaipur National University
Jaipur National University
Affinity DataIC50: 300nMpH: 7.8 T: 2°CAssay Description:HIV-1 Reverse Transcriptase Activity was measured using the colorimetric photometric immunoassay kit provided by Roche. Estimation of RT activity is ...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn
Upjohn
Affinity DataIC50: 320nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant wild type HIV-1 His-tagged reverse transcriptase p66/p51 expressed in Escherichia coli JM109 using poly(rA)/oligo(dT)16 as ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Rome Tor Vergata
Curated by ChEMBL
University Of Rome Tor Vergata
Curated by ChEMBL
Affinity DataIC50: 323nMAssay Description:Inhibition of recombinant wild-type HIV1 GST-fused reverse transcriptase p66/p51 RNA-dependent DNA polymerase activity expressed in Escherichia coli ...More data for this Ligand-Target Pair
