Found 55 of ic50 for monomerid = 50022775 
Affinity DataIC50: 0.0430nMAssay Description:Inhibition of human acetylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against human recombinant AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 18.8nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of guinea pig acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of Wistar rat brain AChE by Ellman colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37.5nMAssay Description:Inhibition of rat brain homogenate AchEMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Wistar rat brain homogenate AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human serum AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 42.1nMAssay Description:Inhibition of human serum AchEMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human serum AChE by Ellman colorimetric assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 47.5nMAssay Description:Inhibition of electric eel AChE by Ellman colorimetric assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 50nMpH: 8.0 T: 2°CAssay Description:Seven different concentrations of the synthesized compounds in the range 10^−3-10^−9 M were measured at 412 nm. All the assays were under...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of electric eel AChE using acetylcholine iodide as substrate after 10 mins by Ellman methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of AChE in rat brain HippocampusMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of equine serum BChE using butylthiocholine iodide as substrate after 10 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMpH: 8.0 T: 2°CAssay Description:Seven different concentrations of the synthesized compounds in the range 10^−3-10^−9 M were measured at 412 nm. All the assays were under...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:In vitro inhibitory activity against acetylcholinesterase from electric eelMore data for this Ligand-Target Pair
Affinity DataIC50: 91.0nMAssay Description:Inhibition acetylcholinesterase (AChE) enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:In vitro inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of AChE in rat brain cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of human plasma BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of AChE (unknown origin) using ACh chloride as substrate preincubated for 15 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.93E+3nMAssay Description:Inhibition of equine BuChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of AChE in rat brain StriatumMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of electrical eel AChE using acetylthiocholine chloride as substrate incubated for 5 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 15...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 1.93E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 2.22E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 2.22E+4nMAssay Description:Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after 15 mins by Ellman's me...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of AChE in rat brain CerebellumMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Mysore
Curated by ChEMBL
University Of Mysore
Curated by ChEMBL
Affinity DataIC50: 4.11E+4nMAssay Description:Inhibition of electric eel AchEMore data for this Ligand-Target Pair
Affinity DataIC50: 4.32E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
Affinity DataIC50: 4.91E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after 15 mins by Ellman's me...More data for this Ligand-Target Pair
Affinity DataIC50: 4.96E+4nMAssay Description:Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.96E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Affinity DataIC50: 4.96E+4nMAssay Description:Inhibition of BuChE in equine serum using butyrylthiocholine chloride as substrate preincubated with enzyme for 10 mins prior to substrate challenge ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.27E+4nMAssay Description:Inhibition of horse serum BChE incubated for 5 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
