Affinity DataIC50: 315nMAssay Description:Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Reverse Proteomics Research Institute
Curated by ChEMBL
Reverse Proteomics Research Institute
Curated by ChEMBL
Affinity DataIC50: 324nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
Solvay Duphar Research Laboratories
Curated by ChEMBL
Solvay Duphar Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Opioid receptors with [3H]naloxone binding in the absence of NaClMore data for this Ligand-Target Pair
Affinity DataIC50: 2.37E+3nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 1(Homo sapiens (Human))
University Medicine Greifswald
Curated by ChEMBL
University Medicine Greifswald
Curated by ChEMBL
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as reduction in ASP+ substrate uptake by microplate reader based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of Opioid receptors binding by inhibiting specific [3H]naloxone binding by 50% in the presence of 100 mM NaClMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Reverse Proteomics Research Institute
Curated by ChEMBL
Reverse Proteomics Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.41E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Reverse Proteomics Research Institute
Curated by ChEMBL
Reverse Proteomics Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.59E+4nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair