TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 0.940nMAssay Description:Inhibition of human ALK6 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Mus musculus)
Massachusetts Institute Of Technology
Massachusetts Institute Of Technology
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human ALK3 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human ALK1 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 12.7nMAssay Description:Inhibition of human ALK6 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Mus musculus)
Massachusetts Institute Of Technology
Massachusetts Institute Of Technology
Affinity DataIC50: 17nMAssay Description:Inhibition of human ALK2 using dephosphorylated casein as substrate measured after 45 mins in presence of [gamma33P]ATP by scintillation counting met...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of ALK2 (unknown origin) using Ulight topo IIa (Thr 1342) peptide as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of ALK3 (unknown origin) using Ulight topo IIa (Thr 1342) peptide as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 19.6nMAssay Description:Inhibition of human ALK1 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 23.4nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human ALK5 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40.7nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of human ALK4 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 43.3nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of ALK6 (unknown origin)More data for this Ligand-Target Pair
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 156nMAssay Description:Inhibition of human TGFBR2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 215nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Affinity DataIC50: 297nMAssay Description:Inhibition of human ALK4 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 339nMAssay Description:Inhibition of human ALK5 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 468nMAssay Description:Inhibition of human ALK5 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 468nMAssay Description:Inhibition of human ALK5 using dephosphorylated casein as substrate measured after 45 mins in presence of [gamma33P]ATP by scintillation counting met...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human ALK5 in presence of (33P)gamma ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 565nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 565nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1/5'-AMP-activated protein kinase subunit gamma-1/Dual specificity protein kinase CLK2(Homo sapiens (Human))
Vanderbilt University
Vanderbilt University
Affinity DataIC50: 1.12E+3nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of ALK4 (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair