Compile Data Set for Download or QSAR
maximum 50k data
Found 12 of ic50 for monomerid = 50406795
TargetType-1 angiotensin II receptor B(RAT)
E. Merck

Curated by ChEMBL
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity against AT1 receptor in the presence of 0.01% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50:  5.5nMAssay Description:In vitro binding affinity of compound against Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50:  8.20nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor B(RAT)
E. Merck

Curated by ChEMBL
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50:  9.80nMAssay Description:Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50:  19nMAssay Description:Angiotensin II receptor antagonist activity was determined by 50% inhibition of specific binding of [3H]angiotensin II (2 nM) to rat adrenal cortical...More data for this Ligand-Target Pair
In DepthDetails
TargetType-1 angiotensin II receptor(Bos taurus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50:  150nMAssay Description:Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50:  8.53E+3nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro binding affinity determined against angiotensin II AT2 receptor in rat adrenal medulla preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro binding affinity of compound against angiotensin II AT-2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50:  3.41E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed