Compile Data Set for Download or QSAR
maximum 50k data
Found 13 of ki for monomerid = 50026612
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  3.80nMAssay Description:The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  3.80nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  5.60nMAssay Description:Inhibition of His6-tagged MELK catalytic domain (1 to 340 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using Bcl-GL as s...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  5.90nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  5.90nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  8nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  8nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  8.40nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  8.40nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  32nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  32nMAssay Description:The inhibitory activities of compounds of the invention against FGFR1 (FGFR1 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR1 prote...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  113nMAssay Description:The inhibitory activities of compounds of the invention against VEGFR1 (VEGFR1 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR1 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  113nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
In DepthDetails US Patent