TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 0.890nMAssay Description:Displacement of [3H]citalopram from SERT in rat brain stem by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]citalopram form human SRET by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H](R,S)-citalopram HBr from human SERTMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [125I]-RTI-55 from human SERT expressed in HEK293 cell membranes after 1 hr by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of wild type human SERT expressed in HEK293 GripTite cells pre-incubated for 5 mins followed by [3H]5-HT addition by [3H]5-HT uptake assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Inhibition of 5-hydroxy[3H]tryptamine uptake at human SERT expressed in African green monkey COS7 cells incubated for 10 mins prior to radioligand ad...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 8.15E+3nMAssay Description:Displacement of [3H]WIN-35428 from DAT in rat caudate-putamen by scintillation countingMore data for this Ligand-Target Pair
TargetTransporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.05E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat frontal cortex by scintillation countingMore data for this Ligand-Target Pair