Compile Data Set for Download or QSAR
maximum 50k data
Found 19 of ki for monomerid = 50370595
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 60 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHOK1 cell membranes incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHOK1 cell membranes incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  30nMAssay Description:Radioligand dose-displacement binding assays for μ-opioid receptors can use 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, CT), with 5 mg mem...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  43.6nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  133nM ΔG°:  -39.2kJ/moleT: 2°CAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  325nMAssay Description:Displacement of [3H]HS-665 from KOR in guinea pig brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  487nMAssay Description:Displacement of [3H]Ile5,6-deltorphin-2 from DOR in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  1.09E+3nMAssay Description:Displacement of [3H[Ile5,6]-deltorphin II from delta opioid receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  2.66E+3nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of 3H](+)-pentazocine from human sigma1 receptor expressed in HEK293 cell membranes incubated for 120 mins by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma-1 receptor transfected in HEK293 membranes incubated for 120 mins measured by microBeta scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]JWH-018 from CB1R/CB2R in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma-1 receptor expressed in HEK293 membranes incubated for 120 mins by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]WIN-55,212-2 from CB1R/CB2R in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed