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Found 2 Enz. Inhib. hit(s) with Target = '[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial' and Ligand = 'BDBM472850'
LigandPNGBDBM472850((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-1-(3-phenyl...)
Affinity DataIC50:  1.65E+3nMAssay Description:The PDC inactivation assay is performed in Greiner 384-well microtiter plates and is used for high throughput screen. 4 μl of PDHK2 (human, rec,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM472850((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-1-(3-phenyl...)
Affinity DataKd: <300nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent