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Found 3 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50195291'
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195291(4-{2-methyl-2-[4-(5-trifluoromethyl-pyridin-2-yl)-...)
Affinity DataKi:  5nMAssay Description:Inhibition of mouse truncated 11beta-HSD1 assessed as inhibition of radiolabeled cortisone to cortisol conversion by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195291(4-{2-methyl-2-[4-(5-trifluoromethyl-pyridin-2-yl)-...)
Affinity DataKi:  9nMAssay Description:Inhibition of human truncated 11beta-HSD1 assessed as inhibition of radiolabeled cortisone to cortisol conversion by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195291(4-{2-methyl-2-[4-(5-trifluoromethyl-pyridin-2-yl)-...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as inhibition of cortisol formation by fluorescent polarization immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed