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Found 5 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50202086'
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202086(CHEMBL219142 | N-[(E)-5-hydroxy-2-adamantyl]-2-{4-...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202086(CHEMBL219142 | N-[(E)-5-hydroxy-2-adamantyl]-2-{4-...)
Affinity DataKi:  8nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202086(CHEMBL219142 | N-[(E)-5-hydroxy-2-adamantyl]-2-{4-...)
Affinity DataKi:  8nMAssay Description:Inhibition of human 11beta-HSD-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202086(CHEMBL219142 | N-[(E)-5-hydroxy-2-adamantyl]-2-{4-...)
Affinity DataKi:  34nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202086(CHEMBL219142 | N-[(E)-5-hydroxy-2-adamantyl]-2-{4-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by FPIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed