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Found 14 Enz. Inhib. hit(s) with Target = '15-hydroxyprostaglandin dehydrogenase [NAD(+)]' and Ligand = 'BDBM347359'
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  0.760nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  1.23nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  1.23nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  2.53nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  2.53nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Rattus norvegicus (Rat))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  2.56nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Mus musculus (Mouse))
Board Of Regents Of The University Of Texas System

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  2.56nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Mus musculus (Mouse))
Board Of Regents Of The University Of Texas System

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  2.56nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Rattus norvegicus (Rat))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  2.74nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Rattus norvegicus (Rat))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  2.74nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Mus musculus (Mouse))
Board Of Regents Of The University Of Texas System

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  2.74nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  56.6nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  56.6nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  56.6nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair
In DepthDetails US Patent