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Found 4 Enz. Inhib. hit(s) with Target = '2-amino-3-carboxymuconate-6-semialdehyde decarboxylase' and Ligand = 'BDBM261610'
Target2-amino-3-carboxymuconate-6-semialdehyde decarboxylase(Homo sapiens (Human))
Tes Pharma

Curated by ChEMBL
LigandPNGBDBM261610(US10513499, Compound 22 | US11254644, Compound 22 ...)
Affinity DataIC50:  316nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target2-amino-3-carboxymuconate-6-semialdehyde decarboxylase(Homo sapiens (Human))
Tes Pharma

Curated by ChEMBL
LigandPNGBDBM261610(US10513499, Compound 22 | US11254644, Compound 22 ...)
Affinity DataIC50:  1.10E+3nMAssay Description:The activity of compounds 1-19 and 21-23 as inhibitors of ACMSD1 was determined by measuring the conversion of 3OH-Anthranilic Acid into product (i.e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-amino-3-carboxymuconate-6-semialdehyde decarboxylase(Homo sapiens (Human))
Tes Pharma

Curated by ChEMBL
LigandPNGBDBM261610(US10513499, Compound 22 | US11254644, Compound 22 ...)
Affinity DataIC50:  1.10E+3nMAssay Description:The pre-assay mixture consisting of 3-hydroxyanthranilic acid (30H-HA), 3-hydroxyanthranilic acid, 3,4-diOxygenase (HAO), and a dialyzed crude extrac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-amino-3-carboxymuconate-6-semialdehyde decarboxylase(Homo sapiens (Human))
Tes Pharma

Curated by ChEMBL
LigandPNGBDBM261610(US10513499, Compound 22 | US11254644, Compound 22 ...)
Affinity DataIC50:  1.10E+3nMAssay Description:The pre-assay mixture consisting of 3-hydroxyanthranilic acid (3OH-HA), 3-hydroxyanthranilic acid, 3,4-diOxygenase (HAO), and a dialyzed crude extrac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent