Found 10 Enz. Inhib. hit(s) with Target = '3-hydroxy-3-methylglutaryl-coenzyme A reductase' and Ligand = 'BDBM50139181'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibitory constant against HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Affinity DataKi: 6.80E+4nMAssay Description:Inhibitory constant against HMG-CoA reductase with alpha asaroneMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of HMG-CoA reductase (unknown origin) using [14C]-HMG-CoA as substrate after 5 mins in presence of NADPHMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against 3-hydroxy-3-methylglutaryl-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Affinity DataIC50: 11.2nMAssay Description:Inhibitory concentration against HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human HMG-CoA reductase after 30 minsMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Universidad Nacional AutóNoma De MéXico
Curated by ChEMBL
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of human HMG-CoA reductase activity using NADPH by spectrophotometricallyMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Schizosaccharomyces pombe)
Instituto Polit£Cnico Nacional (Ipn)
Curated by ChEMBL
Instituto Polit£Cnico Nacional (Ipn)
Curated by ChEMBL
Affinity DataIC50: 9.52E+4nMAssay Description:Inhibition of Schizosaccharomyces pombe HMG-CoA reductase by spectrophotometryMore data for this Ligand-Target Pair