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Found 6 Enz. Inhib. hit(s) with Target = '4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)' and Ligand = 'BDBM50465160'
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50465160(CHEMBL4284707)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of CrtN in linezolid-resistant Staphylococcus aureus NRS271 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50465160(CHEMBL4284707)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of CrtN in vancomycin-intermediate Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophoto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50465160(CHEMBL4284707)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain MW2))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50465160(CHEMBL4284707)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of CrtN in methicillin-resistant Staphylococcus aureus LAC USA300 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain MW2))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50465160(CHEMBL4284707)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of CrtN in methicillin-resistant Staphylococcus aureus USA400 MW2 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50465160(CHEMBL4284707)
Affinity DataIC50:  258nMAssay Description:Inhibition of Staphylococcus aureus Newman Hi6-tagged CrtN expressed in Escherichia coli BL21(DE3))/pET28a::CrtN assessed as reduction in staphyloxan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed