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Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2B' and Ligand = 'BDBM472954'
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM472954((R)-4-(methoxymethyl)-6,6a,7,8,9,10-hexahydro- 5H-...)
Affinity DataKi:  126nMAssay Description:Displacement of [3H]-LSB from recombinant human 5HT2BR transfected in human HEK293 cells incubated for 45 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM472954((R)-4-(methoxymethyl)-6,6a,7,8,9,10-hexahydro- 5H-...)
Affinity DataKi:  138nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM472954((R)-4-(methoxymethyl)-6,6a,7,8,9,10-hexahydro- 5H-...)
Affinity DataEC50:  794nMAssay Description:Agonist activity at 5-HT2BR (unknown origin) transfected in human HEK293 cells by IP3 accumulation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed