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Found 2 Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM50249205'
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50249205(CHEMBL4062753)
Affinity DataIC50:  4nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50249205(CHEMBL4062753)
Affinity DataIC50:  8nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed