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Found 3 Enz. Inhib. hit(s) with Target = 'Acid ceramidase' and Ligand = 'BDBM50238566'
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238566(CHEMBL4075846)
Affinity DataIC50:  15nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238566(CHEMBL4075846)
Affinity DataIC50:  505nMAssay Description:Inhibition of acid ceramidase in human A375 cells using fluorogenic substrate Rbm-14-12 preincubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238566(CHEMBL4075846)
Affinity DataIC50:  928nMAssay Description:Inhibition of acid ceramidase in human G361 cells using fluorogenic substrate Rbm-14-12 preincubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed