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Found 6 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2a' and Ligand = 'BDBM50051241'
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50051241(2-(furan-2-yl)-7-(3-phenylpropyl)-7H-pyrazolo[4,3-...)
Affinity DataKi:  1.20nMAssay Description:Displacement of specific [3H]-SCH- 58261 binding at human Adenosine A2A receptor expressed in HEK-293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50051241(2-(furan-2-yl)-7-(3-phenylpropyl)-7H-pyrazolo[4,3-...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50051241(2-(furan-2-yl)-7-(3-phenylpropyl)-7H-pyrazolo[4,3-...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-ZM 241385 from human adenosine A2A receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50051241(2-(furan-2-yl)-7-(3-phenylpropyl)-7H-pyrazolo[4,3-...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of [3H]-CGS- 21680 binding to Adenosine A2A receptor in rat striatal homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50051241(2-(furan-2-yl)-7-(3-phenylpropyl)-7H-pyrazolo[4,3-...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]-CGS- 21680 from rat striatal membranes Adenosine A2A receptor. Parenthesis indicate 95% confidence limits.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50051241(2-(furan-2-yl)-7-(3-phenylpropyl)-7H-pyrazolo[4,3-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of 1 uM NECA-stimulated cyclic AMP levels in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed