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Found 1 hit Enz. Inhib. hit(s) with Target = 'Aldose reductase-related protein 1' and Ligand = 'BDBM50080469'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase-related protein 1


(Rattus norvegicus)
BDBM50080469
PNG
(CHEMBL3422332)
Show SMILES CCCNC(=O)CSc1nnc2c3cc(C)ccc3n(CC(O)=O)c2n1
Show InChI InChI=1S/C17H19N5O3S/c1-3-6-18-13(23)9-26-17-19-16-15(20-21-17)11-7-10(2)4-5-12(11)22(16)8-14(24)25/h4-5,7H,3,6,8-9H2,1-2H3,(H,18,23)(H,24,25)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.96E+4n/an/an/an/an/an/a



Slovak Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Wistar rat kidney aldehyde reductase using D-glucuronate as substrate by spectrophotometry


J Med Chem 58: 2649-57 (2015)


Article DOI: 10.1021/jm5015814
BindingDB Entry DOI: 10.7270/Q2WS8VZJ
More data for this
Ligand-Target Pair