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Found
1
Enz. Inhib. hit(s) with Target = 'Ataxin-1' and Ligand = 'BDBM474571'
Target
Ataxin-1
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM474571
((E)-1-[(3aS,3bR,6aS,6bR)-5-(1H- benzotriazole-5-ca...)
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Affinity Data
IC50: 8.5nM
Assay Description:
ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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