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Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM26295'
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26295(CHEMBL214849 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26295(CHEMBL214849 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of aurora B in human SW620 cells assessed as inhibition of histone H3 phosphorylationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed