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Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50453821'
TargetAurora kinase B(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50453821(CHEMBL4206831)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant full length His-tagged human Aurora B expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50453821(CHEMBL4206831)
Affinity DataEC50:  11nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in histone H3 phosphorylation at S10 residues after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed