Found 4 Enz. Inhib. hit(s) with Target = 'Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase' and Ligand = 'BDBM50117667'
TargetBeta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
TargetBeta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
TargetBeta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
TargetBeta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 794nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair