Found 2 Enz. Inhib. hit(s) with Target = 'Carbamoyl-phosphate synthase [ammonia], mitochondrial' and Ligand = 'BDBM50542023' TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine
Curated by ChEMBL
H3 Biomedicine
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine
Curated by ChEMBL
H3 Biomedicine
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of CPS1 in human pooled hepatocytes assessed as reduction in urea production measured after 16 hrs in presence of NH4Cl by tecan-plate rea...More data for this Ligand-Target Pair
