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Found 7 Enz. Inhib. hit(s) with Target = 'Catenin beta-1' and Ligand = 'BDBM50094510'
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of N-terminally His6-tagged human beta-catenin (residues 138-686)/C-terminally biotinylated human Tcf4 (residues 7-51) interaction after 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataKi:  7.20E+3nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of human beta-catenin V511S mutant/human wild-type Tcf4 interaction after 1.5 hrs by FP competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataKi:  8.80E+4nMAssay Description:Inhibition of human beta-catenin R469A mutant/human wild-type Tcf4 interaction after 1.5 hrs by FP competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataIC50:  5.50E+5nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein-labeled human E-cadherin (residues 819-873) interaction by FP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataIC50:  6.30E+5nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein-labeled human APC-R3 (residues 1477-1519) interaction by FP co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed