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Found 2 Enz. Inhib. hit(s) with Target = 'Cell division cycle 7-related protein kinase' and Ligand = 'BDBM50506350'
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50506350(Simurosertib | Tak 931 | Tak-931)
Affinity DataIC50:  17nMAssay Description:Inhibition of CDC7 in human HeLa cells assessed as inhibition of MCM2 phosphorylation at Ser40 residue in human HeLa cells after 7 hrs by Western blo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50506350(Simurosertib | Tak 931 | Tak-931)
Affinity DataKd:  0.424nMAssay Description:Binding affinity to CDC7 (unknown origin) assessed as equilibrium dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed