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Found 1 Enz. Inhib. hit(s) with Target = 'Coagulation factor XII' and Ligand = 'BDBM476383'
TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476383(2,3-dihydro-1H-isoindol-5-yl (3S)-4- (N,3-dicycloh...)
Affinity DataIC50:  23.3nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent