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Found 2 Enz. Inhib. hit(s) with Target = 'Coagulation factor XII' and Ligand = 'BDBM476466'
TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476466((2S)-1-[N2-cyclohexyl-N6- (methylsulfonyl)-D-lysyl...)
Affinity DataIC50:  13.5nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476466((2S)-1-[N2-cyclohexyl-N6- (methylsulfonyl)-D-lysyl...)
Affinity DataIC50:  14.2nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent