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Found
1
Enz. Inhib. hit(s) with Target = 'Coagulation factor XII' and Ligand = 'BDBM476506'
Target
Coagulation factor XII
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM476506
((2S)-N-[(3-chloro-1H-indol-5- yl)methyl]-4-[(4S,5S...)
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Affinity Data
IC50: 8.40nM
Assay Description:
The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...
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Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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