Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Cyclin-A2/Cyclin-dependent kinase 2' and Ligand = 'BDBM35655'
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals Inc

LigandPNGBDBM35655(erk000598 | pyrimidylpyrrole, 11c)
Show SMILES Cc1cnc(Nc2cccc(F)c2C)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1
Show InChI InChI=1S/C25H23ClFN5O2/c1-14-11-29-25(31-20-8-4-7-19(27)15(20)2)32-23(14)17-10-21(28-12-17)24(34)30-22(13-33)16-5-3-6-18(26)9-16/h3-12,22,28,33H,13H2,1-2H3,(H,30,34)(H,29,31,32)/t22-/m1/s1
Affinity DataKi:  150nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair