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Found
1
Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 12' and Ligand = 'BDBM478960'
Target
Cyclin-dependent kinase 12
(Homo sapiens)
Aurigene Discovery Technologies
US Patent
Ligand
BDBM478960
(2-(1'-cyano-1',2',3',6'-tetrahydro-[2,4'-bipyridin...)
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Affinity Data
IC50: 4nM
Assay Description:
The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...
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Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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